Compounds > valine

valine and cmpd 167

valine has been researched along with cmpd 167 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeMartino, JA; Doms, RW; Dufour, J; Ketas, TJ; Klasse, PJ; Kuhmann, SE; Kunstman, K; Lifson, JD; Lyons, K; Marx, PA; Mefford, M; Moore, JP; Pandrea, I; Piatak, M; Reeves, JD; Siciliano, SJ; Springer, MS; Veazey, RS; Wolinsky, SM1
Dufour, J; Klasse, PJ; Kunstman, KJ; Marozsan, AJ; Moore, JP; Springer, MS; Veazey, RS; Wolinsky, SM1
Colonno, RJ; Dufour, J; Hu, Q; Ketas, TJ; Klasse, PJ; Lu, M; Marx, PA; Moore, JP; Schader, SM; Shattock, RJ; Springer, MS; Veazey, RS1
Towie, N1
Dufour, J; Klasse, PJ; Marx, PA; Moore, JP; Springer, MS; Veazey, RS1
Ketas, TJ; Klasse, PJ; Lu, M; Moore, JP; Polonis, V; Schader, SM; Teo, E; Zurita, J1
Ahuja, SK; He, W; Ketas, TJ; Klasse, PJ; Kuhmann, SE; Moore, JP; Palmer, A; Zurita, J1
Ayala, JM; Azimzadeh, AM; DeMartino, JA; Iliff, S; Kawka, DW; Lu, M; Lyons, K; Miller, GG; Mills, SG; Mudgett, JS; Nguyen, BN; Peterson, LB; Pierson, RN; Schröder, C; Siciliano, SJ; Singer, II; Springer, MS; Wu, G; Zhang, T1
Hu, Q; Huang, X; Shattock, RJ1
Frank, I; Robbiani, M1
Boyd, P; Doyle, LA; Fetherston, SM; Geer, L; Goldman, L; Ketas, TJ; Klasse, PJ; Lowry, D; Major, I; Malcolm, RK; Moore, JP; Murphy, DJ; Rasmussen, KK; Shattock, RJ; Veazey, RS1
Boyd, P; Geer, L; Goldman, L; Klasse, PJ; Lowry, D; Malcolm, RK; Moore, JP; Shattock, RJ; Veazey, RS1

Other Studies

12 other study(ies) available for valine and cmpd 167

ArticleYear
Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.
    The Journal of experimental medicine, 2003, Nov-17, Volume: 198, Issue:10

    Topics: Animals; Anti-Retroviral Agents; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Macaca mulatta; Pyrazoles; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Valine

2003
Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses.
    Virology, 2004, Oct-10, Volume: 328, Issue:1

    Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Disease Models, Animal; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Macaca mulatta; Pyrazoles; Reassortant Viruses; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Valine; Viral Load; Virus Replication

2004
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.
    Nature, 2005, Nov-03, Volume: 438, Issue:7064

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Antigens; Cell Fusion; Drug Therapy, Combination; Female; HIV; HIV Envelope Protein gp120; HIV Infections; Macaca mulatta; Membrane Fusion; Piperazines; Pyrazoles; Receptors, CCR5; Receptors, Virus; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Time Factors; Vagina; Valine

2005
Drug firms donate compounds for anti-HIV gel.
    Nature, 2005, Nov-03, Volume: 438, Issue:7064

    Topics: Administration, Intravaginal; Africa; Animals; Anti-HIV Agents; Clinical Trials as Topic; Drug Industry; Drug Therapy, Combination; Female; Gels; HIV Infections; Humans; Male; Piperazines; Pyrazoles; Valine

2005
Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor.
    Nature medicine, 2005, Volume: 11, Issue:12

    Topics: Administration, Oral; Animals; CCR5 Receptor Antagonists; Female; Macaca; Pyrazoles; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Time Factors; Vagina; Valine; Viral Load

2005
Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes.
    Virology, 2007, Aug-01, Volume: 364, Issue:2

    Topics: Animals; Anti-Infective Agents, Local; CCR5 Receptor Antagonists; Drug Evaluation, Preclinical; Drug Interactions; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; In Vitro Techniques; Male; Piperazines; Pyrazoles; Pyridines; Receptors, CXCR4; Sexual Behavior; Valine; Virus Internalization

2007
Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands.
    Virology, 2007, Aug-01, Volume: 364, Issue:2

    Topics: Animals; Antibodies, Monoclonal; CCR5 Receptor Antagonists; CD4 Antigens; Chemokines, CC; Cyclohexanes; Gene Dosage; HeLa Cells; HIV-1; Humans; In Vitro Techniques; Ligands; Lymphocytes; Macaca mulatta; Maraviroc; Piperazines; Pyrazoles; Pyrimidines; Receptors, CCR5; Simian Immunodeficiency Virus; Triazoles; Valine

2007
CCR5 blockade modulates inflammation and alloimmunity in primates.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Aug-15, Volume: 179, Issue:4

    Topics: Animals; Antibody Formation; Autoimmunity; CCR5 Receptor Antagonists; Cyclosporine; Disease Models, Animal; Graft Survival; Heart Transplantation; HIV Infections; Humans; Immunosuppressive Agents; Inflammation; Isoantibodies; Kidney Transplantation; Macaca fascicularis; Macrophages; Male; Pyrazoles; Stress, Physiological; T-Lymphocytes; Transplantation Tolerance; Transplantation, Homologous; Valine; Vascular Diseases

2007
C-C chemokine receptor type 5 (CCR5) utilization of transmitted and early founder human immunodeficiency virus type 1 envelopes and sensitivity to small-molecule CCR5 inhibitors.
    The Journal of general virology, 2010, Volume: 91, Issue:Pt 12

    Topics: Amides; Antibodies, Monoclonal; CCR5 Receptor Antagonists; Cyclohexanes; env Gene Products, Human Immunodeficiency Virus; HIV Fusion Inhibitors; HIV-1; Humans; Maraviroc; Protein Binding; Pyrazoles; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, HIV; Triazoles; Valine; Virus Internalization

2010
Attachment and fusion inhibitors potently prevent dendritic cell-driven HIV infection.
    Journal of acquired immune deficiency syndromes (1999), 2011, Mar-01, Volume: 56, Issue:3

    Topics: Anti-HIV Agents; Cells, Cultured; Coculture Techniques; Dendritic Cells; HIV; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Peptide Fragments; Pyrazoles; T-Lymphocytes; Valine; Virus Replication

2011
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Biopsy; CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Contraceptive Devices, Female; Cyclohexanes; Delayed-Action Preparations; Female; HIV Infections; HIV-1; Humans; Longitudinal Studies; Macaca mulatta; Maraviroc; Medroxyprogesterone Acetate; Pyrazoles; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tissue Distribution; Triazoles; Vagina; Valine; Virus Internalization

2012
Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5

    Topics: Administration, Intravaginal; Administration, Oral; Administration, Rectal; Animals; Anti-HIV Agents; Body Fluids; CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Female; Macaca mulatta; Male; Mass Spectrometry; Pyrazoles; Receptors, HIV; Valine

2014