valine and 2-keto-4-methylvalerate

valine has been researched along with 2-keto-4-methylvalerate in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199023 (56.10)18.7374
1990's9 (21.95)18.2507
2000's6 (14.63)29.6817
2010's2 (4.88)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Schlegel, HG; Wiegel, J1
Bensch, KG; Herman, MM; Liao, CL1
Hoerr, RA; Marks, L; Pelletier, V; Wagner, DA; Young, VR1
Shiota, T; Swain, LM; Walser, M1
Beck, K; Schadewaldt, P; Wendel, U1
Lenzen, S; Panten, U; Schmidt, W1
Kasperek, GJ1
Baker, DH; Funk, MA; Lowry, KR1
Blinder, L; Frick, GP; Goodman, HM1
Harper, AE; Miller, RH2
Herbertz, L; Langer, K; Schauder, P1
Herbertz, L; Langer, K; Schauder, P; Zavelberg, D1
Broyer, M; Dodu, C; Kamoun, PP; Kleinknecht, C; Laouari, D; Rocchiccioli, F1
Aftring, RP; Buse, MG; Manos, PN1
Schauder, P1
Henning, HV; Langenbeck, U; Matthaei, D; Schauder, P; Schröder, K1
Block, KP; Harper, AE; Miller, RH1
Goldstein, F; Norton, PM; Sansaricq, C; Snyderman, SE1
Frost, SC; Wells, MA1
Hutton, JC; Malaisse, WJ; Sener, A1
Baker, DH; Boebel, KP1
Harper, AE; Hutson, SM1
McCully, V; Roberts, CM; Sokatch, JR1
Cordewener, JH; van Hinsbergh, VW; Veerkamp, JH1
Deferrari, G; Fiorini, F; Garibotto, G; Paoletti, E; Robaudo, C; Russo, R; Tizianello, A1
Hoffer, LJ; Mamer, OA; Reimer, ML; Robitaille, L; Taveroff, A1
Drechsel, H; Jung, G; Reissbrodt, R; Thieken, A; Winkelmann, G1
Holecek, M; Skopec, F; Sprongl, L; Tilser, I1
Thompson, JR; Zhou, X1
Hamadeh, MJ; Hoffer, LJ; Mamer, OA; Robitaille, L; Taveroff, A1
Hammen, HW; Ott, AC; Schadewaldt, P; Wendel, U1
Dutra-Filho, CS; Santos, CE; Souza, DO; Tasca, CI; Tavares, RG; Wajner, M1
Holecek, M; Sprongl, L; Tilser, I1
Bungo, T; Izumi, T; Kawamura, K; Ueda, H1
Beck, HC; Hansen, AM; Lauritsen, FR1
Hirayama, S; Nagasawa, T; Sekizawa, H; Sugahara, K; Yamazaki, Y; Yoshizawa, F1
Babraj, JA; Crameri, RM; Døssing, S; Flyvbjerg, A; Hansen, M; Kjaer, M; Langberg, H; Miller, BF; Olesen, JL; Rennie, MJ; Smith, K; Welling, RJ1
Qi, L; Qiao, J; Yang, G; Zhang, H1
Duvekot, JJ; Minderman, G; Schierbeek, H; Schoonderwaldt, EM; Steegers, EA; van den Akker, CH; van Goudoever, JB; Vermes, A1
Angela, C; Runguphan, W; Siripong, W; Tanapongpipat, S1

Reviews

1 review(s) available for valine and 2-keto-4-methylvalerate

ArticleYear
Branched-chain amino acid metabolism.
    Annual review of nutrition, 1984, Volume: 4

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Chemical Phenomena; Chemistry, Physical; Cytosol; Dietary Proteins; Enzyme Activation; Hemiterpenes; Hormones; Humans; Isoenzymes; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kinetics; Leucine; Liver; Mitochondria; Multienzyme Complexes; Nitrogen; Oxidation-Reduction; Substrate Specificity; Tissue Distribution; Transaminases; Valine

1984

Trials

1 trial(s) available for valine and 2-keto-4-methylvalerate

ArticleYear
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes.
    The American journal of clinical nutrition, 1991, Volume: 54, Issue:2

    Topics: Adult; Carbon Isotopes; Humans; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Valine

1991

Other Studies

39 other study(ies) available for valine and 2-keto-4-methylvalerate

ArticleYear
Alpha-isopropylmalate synthase from Alcaligenes eutrophus H 16. III. Endproduct inhibition and its relief by valine and isoleucine.
    Archives of microbiology, 1977, Sep-28, Volume: 114, Issue:3

    Topics: 2-Isopropylmalate Synthase; Alcaligenes; Caproates; Histidine; Hydrogen-Ion Concentration; Isoleucine; Keto Acids; Kinetics; Leucine; Oxo-Acid-Lyases; Temperature; Valine

1977
Prolongation of G1 and S phase in C-6 glioma cells treated with maple syrup urine disease metabolits. Morphologic and cell cycle studies.
    Laboratory investigation; a journal of technical methods and pathology, 1978, Volume: 38, Issue:2

    Topics: Caproates; Cell Count; Cell Cycle; Cell Line; Humans; Interphase; Isoleucine; Keto Acids; Kinetics; Leucine; Maple Syrup Urine Disease; Mitosis; Neuroglia; Valine

1978
Utilization for protein synthesis of leucine and valine compared with their keto analogues.
    The American journal of clinical nutrition, 1990, Volume: 51, Issue:3

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Hemiterpenes; Intracellular Membranes; Keto Acids; Leucine; Liver; Male; Myocardium; Nutritional Requirements; Oxidation-Reduction; Protein Biosynthesis; Rats; Rats, Inbred Strains; Salivary Glands; Valine

1990
Analysis of maple syrup urine disease in cell culture: use of substrates.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Sep-15, Volume: 184, Issue:1

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Cells, Cultured; Fibroblasts; Hemiterpenes; Humans; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Maple Syrup Urine Disease; Multienzyme Complexes; Substrate Specificity; Valine

1989
Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Animals; Caproates; Cytoplasm; Glutamates; Glutamic Acid; Glutamine; Hemiterpenes; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Mice; Mice, Obese; Mitochondria; Transaminases; Valine

1985
Regulation of branched-chain 2-oxo acid dehydrogenase activity during exercise.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adenosine Triphosphate; Amino Acids, Branched-Chain; Animals; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Muscles; Physical Exertion; Rats; Rats, Inbred Strains; Valine

1989
Utilization of the L- and DL-isomers of alpha-keto-beta-methylvaleric acid by rats and comparative efficacy of the keto analogs of branched-chain amino acids provided as ornithine, lysine and histidine salts.
    The Journal of nutrition, 1987, Volume: 117, Issue:9

    Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Eating; Hemiterpenes; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Male; Ornithine; Rats; Rats, Inbred Strains; Salts; Stereoisomerism; Valine

1987
Transamination and oxidation of leucine and valine in rat adipose tissue.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adipose Tissue; Animals; Carbon Dioxide; Enzyme Activation; Glucose; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Kinetics; Leucine; Male; Multienzyme Complexes; Oxidation-Reduction; Rats; Transaminases; Valine

1988
Regulation of valine and alpha-ketoisocaproate metabolism in rat kidney mitochondria.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 1

    Topics: Animals; Calcium; Caproates; Detergents; Keto Acids; Kidney; Kinetics; Male; Mitochondria; Octoxynol; Oxidation-Reduction; Polyethylene Glycols; Rats; Valine

1988
[Plasma level of branched-chain amino and keto acids in healthy subjects after an intravenous dose of MCT/LCT or LCT].
    Beitrage zu Infusionstherapie und klinische Ernahrung, 1988, Volume: 20

    Topics: Adult; Amino Acids, Branched-Chain; Caproates; Fasting; Fat Emulsions, Intravenous; Female; Hemiterpenes; Humans; Infusions, Intravenous; Insulin; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Random Allocation; Triglycerides; Valerates; Valine

1988
Sex-specific differences in plasma branched-chain keto acid levels in obesity.
    The American journal of clinical nutrition, 1987, Volume: 46, Issue:1

    Topics: Blood Glucose; Body Composition; Female; Hemiterpenes; Humans; Insulin; Insulin Resistance; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Obesity; Sex Characteristics; Valine

1987
Efficiency of substitution of 2-ketoisocaproic acid and 2-ketoisovaleric acid in the diet of normal and uremic growing rats.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:6

    Topics: Animals; Diet; Growth; Hemiterpenes; Keto Acids; Leucine; Male; Nitrogen; Nutritive Value; Rats; Rats, Inbred Strains; Urea; Uremia; Valine

1986
Catabolism of branched-chain amino acids by diaphragm muscles of fasted and diabetic rats.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:8

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amination; Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Experimental; Diaphragm; Fasting; In Vitro Techniques; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Muscles; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Transaminases; Valine

1985
Pharmacokinetic and metabolic interrelationships among branched-chain keto and amino acids in humans.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:6

    Topics: Adult; Amino Acids, Branched-Chain; Drug Interactions; Female; Half-Life; Hemiterpenes; Humans; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Reference Values; Time Factors; Valine

1985
Influence of insulin on blood levels of branched chain keto and amino acids in man.
    Metabolism: clinical and experimental, 1983, Volume: 32, Issue:4

    Topics: Adult; Amino Acids, Branched-Chain; Blood Glucose; Female; Hemiterpenes; Hormones; Humans; Insulin; Isoleucine; Keto Acids; Leucine; Male; Valine

1983
The relationship between the branched chain amino acids and their alpha-ketoacids in maple syrup urine disease.
    Pediatric research, 1984, Volume: 18, Issue:9

    Topics: Amino Acids, Branched-Chain; Caproates; Child; Child, Preschool; Female; Hemiterpenes; Humans; Infant; Infant, Newborn; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Valerates; Valine

1984
Metabolism of valine and 3-methyl-2-oxobutanoate by the isolated perfused rat kidney.
    The Biochemical journal, 1984, Nov-15, Volume: 224, Issue:1

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Hemiterpenes; In Vitro Techniques; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kidney; Leucine; Male; Multienzyme Complexes; Oxidation-Reduction; Perfusion; Rats; Valine

1984
Metabolism of branched-chain keto acids in neonatal rat liver perfusions.
    Archives of biochemistry and biophysics, 1983, Oct-15, Volume: 226, Issue:2

    Topics: Animals; Animals, Newborn; Decanoic Acids; Hemiterpenes; Keto Acids; Kinetics; Leucine; Liver; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains; Valine

1983
The stimulus-secretion coupling of amino acid-induced insulin release. Synergistic effects of L-glutamine and 2-keto acids upon insulin secretion.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Caproates; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Rats; Valine

1981
Comparative utilization of the alpha-keto and D- and L-alpha-hydroxy analogs of leucine, isoleucine and valine by chicks and rats.
    The Journal of nutrition, 1982, Volume: 112, Issue:10

    Topics: Animals; Caproates; Chickens; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Male; Pentanoic Acids; Rats; Species Specificity; Structure-Activity Relationship; Valerates; Valine

1982
Blood and tissue branched-chain amino and alpha-keto acid concentrations: effect of diet, starvation, and disease.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:2

    Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Experimental; Diet; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Rats; Starvation; Valine

1981
Purification of a branched-chain keto acid dehydrogenase from Pseudomonas putida.
    Journal of bacteriology, 1981, Volume: 148, Issue:2

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Caproates; Coenzyme A; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Kinetics; Multienzyme Complexes; NAD; Pentanoic Acids; Pseudomonas; Substrate Specificity; Valine

1981
Degradation of branched-chain amino acids and 2-oxo acids in human and rat muscle.
    Biochemical medicine, 1980, Volume: 24, Issue:2

    Topics: Amino Acids, Branched-Chain; Animals; Carnitine; Hemiterpenes; Humans; Keto Acids; Leucine; Liver; Male; Mitochondria, Muscle; Muscles; Oxidation-Reduction; Rats; Valine

1980
Peripheral metabolism of branched-chain keto acids in patients with chronic renal failure.
    Mineral and electrolyte metabolism, 1993, Volume: 19, Issue:1

    Topics: Adult; Amino Acids, Branched-Chain; Bicarbonates; Female; Hemiterpenes; Humans; Isoleucine; Keto Acids; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Valine

1993
Alpha-keto and alpha-hydroxy branched-chain acid interrelationships in normal humans.
    The Journal of nutrition, 1993, Volume: 123, Issue:9

    Topics: Adult; Amino Acids, Branched-Chain; Dietary Proteins; Evaluation Studies as Topic; Fasting; Female; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Mass Spectrometry; Oxidation-Reduction; Protein Binding; Time Factors; Valerates; Valine

1993
Alpha-keto acids are novel siderophores in the genera Proteus, Providencia, and Morganella and are produced by amino acid deaminases.
    Journal of bacteriology, 1993, Volume: 175, Issue:9

    Topics: Amino Acids; Biological Assay; Biological Transport; Caproates; Chromatography, High Pressure Liquid; Deamination; Enterobacteriaceae; Hydroxamic Acids; Iron; Keto Acids; Lactates; Leucine; Phenylalanine; Phenylpyruvic Acids; Proteus; Providencia; Siderophores; Structure-Activity Relationship; Tryptophan; Valine

1993
Leucine metabolism in rats with cirrhosis.
    Journal of hepatology, 1996, Volume: 24, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Evaluation Studies as Topic; In Vitro Techniques; Isoleucine; Keto Acids; Leucine; Liver; Liver Cirrhosis, Experimental; Male; Oxidation-Reduction; Perfusion; Protein Biosynthesis; Rats; Rats, Wistar; Valine

1996
Regulation of glutamate dehydrogenase by branched-chain amino acids in skeletal muscle from rats and chicks.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:7

    Topics: Acidosis; Amino Acids, Branched-Chain; Ammonium Chloride; Animals; Chickens; Glutamate Dehydrogenase; Glutamine; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Valine

1996
Effects of leucine on whole body leucine, valine, and threonine metabolism in humans.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Adult; Amino Acids; Biotransformation; Carbon Isotopes; Deuterium; Female; Hemiterpenes; Humans; Keto Acids; Kinetics; Leucine; Male; Radioisotope Dilution Technique; Threonine; Time Factors; Valine

1997
Renal clearance of branched-chain L-amino and 2-oxo acids in maple syrup urine disease.
    Journal of inherited metabolic disease, 1999, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Amino Acids, Branched-Chain; Child; Child, Preschool; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Metabolic Clearance Rate; Middle Aged; Valine

1999
Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease.
    Journal of the neurological sciences, 2000, Dec-01, Volume: 181, Issue:1-2

    Topics: Animals; Brain; Glutamic Acid; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Neurons; Rats; Rats, Wistar; Synaptic Vesicles; Synaptosomes; Valine

2000
Metabolism of branched-chain amino acids in starved rats: the role of hepatic tissue.
    Physiological research, 2001, Volume: 50, Issue:1

    Topics: Alanine Transaminase; Amino Acids, Branched-Chain; Animals; Aspartate Aminotransferases; Glucose; Isoleucine; Keto Acids; Leucine; Liver; Male; Muscle, Skeletal; Organ Size; Oxidation-Reduction; Potassium; Protein Biosynthesis; Proteins; Rats; Rats, Wistar; Sodium; Starvation; Valine

2001
Central administration of leucine, but not isoleucine and valine, stimulates feeding behavior in neonatal chicks.
    Neuroscience letters, 2004, Jan-09, Volume: 354, Issue:2

    Topics: Animals; Animals, Newborn; Appetite Regulation; Brain; Chickens; Feeding Behavior; Glutamic Acid; Hyperphagia; Isoleucine; Keto Acids; Leucine; Male; Reaction Time; Valine

2004
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus.
    Journal of applied microbiology, 2004, Volume: 96, Issue:5

    Topics: Cell Membrane; Chromatography; Culture Media; Fatty Acids; Flavoring Agents; Food Microbiology; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Meat Products; Oxidation-Reduction; Pentanoic Acids; Pyruvic Acid; Staphylococcus; Valine

2004
Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate.
    Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:1

    Topics: Animals; Carrier Proteins; Food Deprivation; Intracellular Signaling Peptides and Proteins; Isoleucine; Keto Acids; Leucine; Liver; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 90-kDa; Stereoisomerism; Valine

2004
Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise.
    The Journal of physiology, 2005, Sep-15, Volume: 567, Issue:Pt 3

    Topics: Adult; Carbon Radioisotopes; Collagen; Exercise; Hemiterpenes; Humans; Keto Acids; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Nitrogen Radioisotopes; Patella; Proline; Sarcoplasmic Reticulum; Tendons; Thigh; Valine

2005
A chiral ligand exchange CE essay with zinc(II)-L-valine complex for determining enzyme kinetic constant of L-amino acid oxidase.
    Talanta, 2010, Jun-15, Volume: 81, Issue:4-5

    Topics: Animals; Biochemistry; Catalysis; Chemistry Techniques, Analytical; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Keto Acids; Kinetics; L-Amino Acid Oxidase; Ligands; Snake Venoms; Snakes; Stereoisomerism; Substrate Specificity; Valine; Zinc

2010
Amino acid metabolism in the human fetus at term: leucine, valine, and methionine kinetics.
    Pediatric research, 2011, Volume: 70, Issue:6

    Topics: Blood Flow Velocity; Carbon Isotopes; Female; Fetal Blood; Fetus; Hemiterpenes; Humans; Keto Acids; Kinetics; Leucine; Mass Spectrometry; Maternal-Fetal Exchange; Methionine; Nitrogen Isotopes; Pregnancy; Statistics, Nonparametric; Valine

2011
Metabolic engineering of Pichia pastoris for production of isopentanol (3-Methyl-1-butanol).
    Enzyme and microbial technology, 2020, Volume: 138

    Topics: Biofuels; Biosynthetic Pathways; Fungal Proteins; Gene Editing; Gene Expression; Glucose; Keto Acids; Leucine; Metabolic Engineering; Pentanols; Saccharomycetales; Valine

2020