Page last updated: 2024-09-04

valerylsalicylate and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

valerylsalicylate has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 9 studies

Compound Research Comparison

Studies
(valerylsalicylate)
Trials
(valerylsalicylate)
Recent Studies (post-2010)
(valerylsalicylate)
Studies
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Trials
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Recent Studies (post-2010) (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
24051,2203229

Protein Interaction Comparison

ProteinTaxonomyvalerylsalicylate (IC50)n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide (IC50)
Prostaglandin E synthaseHomo sapiens (human)10
Prostaglandin G/H synthase 1Ovis aries (sheep)2.1
AromataseHomo sapiens (human)0.68
Prostaglandin G/H synthase 1Mus musculus (house mouse)1.67
Prostaglandin G/H synthase 1Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)0.9037
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4333
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.1522
Carboxypeptidase B2Homo sapiens (human)1.8
Prostaglandin E synthaseMus musculus (house mouse)0.007

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's7 (77.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaminski, DL; Longo, WE; Mazuski, J; Panesar, N1
Briggs, JP; Schnermann, J; Smart, A; Traynor, TR1
Davidson, ME; Lang, RJ1
Eriksson, E; Hellstrand, M; Nilsson, CL1
Calixto, JB; El Sayah, M1
Fortier, MA; Parent, J; Villeneuve, C1
Bratz, IN; Kanagy, NL1
Feletou, M; Gluais, P; Lonchampt, M; Morrow, JD; Vanhoutte, PM1
Huang, A; Jacobson, A; Kaley, G; Liu, H; Ojaimi, C; Sun, D; Yan, C1

Other Studies

9 other study(ies) available for valerylsalicylate and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ArticleYear
Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents.
    Prostaglandins & other lipid mediators, 1998, Volume: 56, Issue:5-6

    Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Epithelial Cells; Humans; Immunoblotting; Interleukin-1; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate

1998
Inhibition of macula densa-stimulated renin secretion by pharmacological blockade of cyclooxygenase-2.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Isoenzymes; Juxtaglomerular Apparatus; Kidney Tubules, Distal; Nitrobenzenes; Osmolar Concentration; Prostaglandin-Endoperoxide Synthases; Rabbits; Renin; Salicylates; Sodium Chloride; Sulfonamides

1999
Effects of selective inhibitors of cyclo-oxygenase-1 (COX-1) and cyclo-oxygenase-2 (COX-2) on the spontaneous myogenic contractions in the upper urinary tract of the guinea-pig and rat.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Indomethacin; Isoenzymes; Kidney Pelvis; Male; Membrane Proteins; Muscle Contraction; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Sulfonamides; Ureter

2000
Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent.
    Biochemical pharmacology, 2002, Jun-15, Volume: 63, Issue:12

    Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; CHO Cells; Cricetinae; Cyclooxygenase 2; Dinoprostone; Dopamine; Dopamine Antagonists; Drug Interactions; Enzyme Inhibitors; Gallic Acid; Indomethacin; Isoenzymes; Naphthalenes; Nitrobenzenes; Phosphatidylcholines; Prostaglandin-Endoperoxide Synthases; Pyrones; Quinacrine; Receptors, Dopamine D2; Salicylamides; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection

2002
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
    European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2

    Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanethidine; Ibuprofen; Imidazoles; In Vitro Techniques; Indomethacin; Iris; Kallidin; Muscle Contraction; Muscle, Smooth; Nitrobenzenes; Propionates; Quinolines; Salicylates; Sulfonamides; Swine; Tetrodotoxin; Thromboxane-A Synthase

2003
Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium.
    Reproduction (Cambridge, England), 2003, Volume: 126, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blotting, Western; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrium; Epithelial Cells; Female; Flurbiprofen; Isoenzymes; Nitrobenzenes; Oxytocin; Prostaglandin-Endoperoxide Synthases; Salicylates; Stimulation, Chemical; Sulfonamides

2003
Nitric oxide synthase-inhibition hypertension is associated with altered endothelial cyclooxygenase function.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Isoenzymes; Male; Membrane Proteins; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Nitrobenzenes; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Salicylates; Sulfonamides; Vasoconstriction

2004
Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin.
    British journal of pharmacology, 2005, Volume: 146, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Imidazoles; In Vitro Techniques; Indomethacin; Nitrobenzenes; Prostaglandins; Prostaglandins I; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Salicylates; Sulfonamides; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents

2005
COX-2 contributes to the maintenance of flow-induced dilation in arterioles of eNOS-knockout mice.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:3

    Topics: Animals; Arterioles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Male; Membrane Proteins; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitrobenzenes; Prostaglandins; Regional Blood Flow; Salicylates; Sulfonamides; Vasodilation

2006