valerates has been researched along with ridogrel in 8 studies
| Studies (valerates) | Trials (valerates) | Recent Studies (post-2010) (valerates) | Studies (ridogrel) | Trials (ridogrel) | Recent Studies (post-2010) (ridogrel) |
|---|---|---|---|---|---|
| 2,251 | 294 | 457 | 90 | 10 | 1 |
| Protein | Taxonomy | valerates (IC50) | ridogrel (IC50) |
|---|---|---|---|
| Thromboxane A2 receptor | Homo sapiens (human) | 2.48 | |
| Thromboxane-A synthase | Homo sapiens (human) | 0.0062 | |
| Thromboxane-A synthase | Rattus norvegicus (Norway rat) | 0.006 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banić, A; Kouris, K; Nazal, M; Rajacić, N; Thulesius, O | 1 |
| Arnout, J; De Reys, S; Deckmyn, H; Falcon, C; Hoet, B; Vermylen, J | 1 |
| Beetens, J; De Clerck, F; Janssen, PA; Van de Water, A; Vercammen, E | 1 |
| Beetens, J; de Chaffoy de Courcelles, D; De Clerck, F; Freyne, E; Janssen, PA; Vercammen, E | 1 |
| Aoki, N; Johnson, G; Lefer, AM; Siegfried, MR | 1 |
| Beetens, J; de Chaffoy de Courcelles, D; De Clerck, F; Freyne, E; Janssen, PA | 1 |
| Arnout, J; Hoet, B; Vermylen, J | 1 |
| Lumley, P; Watts, IS; Wharton, KA; White, BP | 1 |
2 trial(s) available for valerates and ridogrel
| Article | Year |
|---|---|
R68070, a combined thromboxane/endoperoxide receptor antagonist and thromboxane synthase inhibitor, inhibits human platelet activation in vitro and in vivo: a comparison with aspirin.
Topics: Aspirin; Bleeding Time; Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Double-Blind Method; Humans; In Vitro Techniques; Pentanoic Acids; Phosphoproteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Valerates | 1990 |
R68070, a combined thromboxane/endoperoxide receptor antagonist (TRA) and thromboxane synthase inhibitor (TSI), prolongs the bleeding time more than aspirin in man.
Topics: Aspirin; Bleeding Time; Blood Platelets; Clinical Trials as Topic; Cyclic AMP; Double-Blind Method; Humans; In Vitro Techniques; Male; Pentanoic Acids; Prostaglandins; Pyridines; Random Allocation; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane-A Synthase; Valerates | 1989 |
6 other study(ies) available for valerates and ridogrel
| Article | Year |
|---|---|
Increased skin flap viability after treatment with forskolin or with ridogrel, a thromboxane synthesis inhibitor and receptor blocker.
Topics: Animals; Colforsin; Graft Survival; Male; Microcirculation; Pentanoic Acids; Pyridines; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Skin; Surgical Flaps; Thromboxane A2; Valerates | 1990 |
R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--II. Pharmacological effects in vivo and ex vivo.
Topics: Adult; Animals; Arrhythmias, Cardiac; Blood Coagulation; Coronary Thrombosis; Dogs; Fibrinolysis; Hemostasis; Humans; In Vitro Techniques; Male; Middle Aged; Myocardial Reperfusion Injury; Pentanoic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane-A Synthase; Valerates | 1989 |
R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade, combined in one molecule.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides; Pyridines; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase; Valerates | 1989 |
Protective effects of a combination thromboxane synthesis inhibitor-receptor antagonist, R-68070, during murine traumatic shock.
Topics: Animals; Cathepsin D; Male; Myocardial Depressant Factor; Pentanoic Acids; Pyridines; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Shock, Traumatic; Thromboxane A2; Thromboxane-A Synthase; Valerates | 1989 |
R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--I. Biochemical profile in vitro.
Topics: Animals; Arachidonic Acids; Blood Platelets; Cyclic AMP; Humans; In Vitro Techniques; Pentanoic Acids; Phosphatidylinositols; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Pyridines; Rabbits; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Sheep; Thromboxane B2; Thromboxane-A Synthase; Valerates | 1989 |
Comparison of GR32191, R68070 and CV-4151 upon U-46619- and collagen-induced platelet aggregation in vitro and ex vivo.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Collagen; Fatty Acids, Monounsaturated; Heptanoic Acids; Humans; In Vitro Techniques; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thromboxane-A Synthase; Valerates | 1989 |