valdecoxib has been researched along with ketorolac in 5 studies
| Studies (valdecoxib) | Trials (valdecoxib) | Recent Studies (post-2010) (valdecoxib) | Studies (ketorolac) | Trials (ketorolac) | Recent Studies (post-2010) (ketorolac) |
|---|---|---|---|---|---|
| 375 | 71 | 86 | 1,778 | 668 | 725 |
| Protein | Taxonomy | valdecoxib (IC50) | ketorolac (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.013 | |
| Caspase-1 | Homo sapiens (human) | 1.3025 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.282 | |
| Caspase-3 | Homo sapiens (human) | 1.3025 | |
| Caspase-4 | Homo sapiens (human) | 1.3025 | |
| Caspase-5 | Homo sapiens (human) | 1.3025 | |
| Caspase-9 | Homo sapiens (human) | 1.3025 | |
| Cell division control protein 42 homolog | Homo sapiens (human) | 2 | |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Daniels, S; Desjardins, PJ; Hubbard, RC; Mehlisch, DR | 1 |
| Al-Ghawas, M; Alkhiary, YM; Cullinane, DM; Einhorn, TA; Fitch, JL; Gerstenfeld, LC; Krall, EA; Thiede, MA; Webb, EG | 1 |
| Macedo, GM; Medeiros, BA; Nobre-e-Souza, MA; Palheta-Junior, RC; Santos, AA; Santos, CL; Souza, MH; Troncon, LE | 1 |
| Boutary, M; Dorr, LD; Long, WT; Raya, J; Sirianni, LE | 1 |
1 review(s) available for valdecoxib and ketorolac
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for valdecoxib and ketorolac
| Article | Year |
|---|---|
Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery.
Topics: Adult; Analgesics; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoenzymes; Isoxazoles; Ketorolac; Male; Membrane Proteins; Molar, Third; Pain Measurement; Pain, Postoperative; Prodrugs; Prostaglandin-Endoperoxide Synthases; Safety; Sulfonamides; Survival Analysis; Time Factors; Tooth Extraction | 2003 |
Multimodal analgesia without parenteral narcotics for total knee arthroplasty.
Topics: Administration, Oral; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Aspirin; Catheters, Indwelling; Celecoxib; Drug Administration Schedule; Drug Therapy, Combination; Femoral Nerve; Hip Joint; Humans; Injections, Intra-Articular; Isoxazoles; Ketorolac; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies; Pyrazoles; Ropivacaine; Sulfonamides | 2008 |
2 other study(ies) available for valdecoxib and ketorolac
| Article | Year |
|---|---|
Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment.
Topics: Animals; Biomechanical Phenomena; Bony Callus; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Fracture Fixation, Intramedullary; Fracture Healing; Fractures, Bone; Fractures, Ununited; Isoxazoles; Ketorolac; Male; Rats; Rats, Sprague-Dawley; Sulfonamides | 2007 |
Cyclooxygenase-2 inhibition increases gastric tone and delays gastric emptying in rats.
Topics: Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Gastric Emptying; Gastric Mucosa; Indomethacin; Isoxazoles; Ketorolac; Lactones; Male; Muscle, Smooth; Pyrazoles; Rats; Rats, Wistar; Stomach; Sulfonamides; Sulfones | 2007 |