vadocaine has been researched along with diphenhydramine hydrochloride in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karttunen, P; Mykkänen, M; Ottoila, P; Silvasti, M; Tukiainen, H | 1 |
| Hänninen, U; Karttunen, P; Mykkänen, M; Silvasti, M; Tukiainen, H; Välttilä, S | 1 |
| Kangasaho, M | 1 |
| Algate, DR; Baines, MW; Davies, JE; Karttunen, P; Lahovaara, S; Männistö, PT; Nissinen, E | 1 |
| Havas, A; Karttunen, P; Lahovaara, S; Männistö, PT | 1 |
| Salonen, RO | 1 |
| Paakkari, I; Svartström-Fraser, M | 1 |
| Ahtee, L; Etemadzadeh, E; Männistö, PT | 1 |
| Männistö, PT; Mäntylä, R; Nissinen, E; Vuorela, A | 1 |
| Männistö, PT; Mäntylä, R; Vuorela, A | 1 |
| Karttunen, P; Männistö, PT; Tukiainen, H; Uusitupa, M | 1 |
| Karttunen, P; Männistö, PT; Nissinen, E; Tukiainen, H; Uusitupa, M | 1 |
| Karttunen, P | 1 |
| Helin, M; Karttunen, P; Silvasti, M; Tukiainen, H; Uusitupa, M | 1 |
3 trial(s) available for vadocaine and diphenhydramine hydrochloride
| Article | Year |
|---|---|
The single dose and steady-state pharmacokinetics of a vadocaine tablet in healthy human volunteers.
Topics: Adult; Antitussive Agents; Humans; Male; Piperidines; Random Allocation; Solutions; Tablets | 1989 |
First human studies on the safety and antitussive activity of vadocaine hydrochloride.
Topics: Adult; Antitussive Agents; Blood Chemical Analysis; Blood Pressure; Cough; Drug Evaluation; Electrocardiography; Heart Rate; Humans; Male; Piperidines | 1988 |
Assessment of the antitussive effect of vadocaine hydrochloride using citric acid-induced cough in healthy volunteers.
Topics: Adult; Antitussive Agents; Citrates; Citric Acid; Cough; Double-Blind Method; Humans; Male; Piperidines | 1988 |
12 other study(ies) available for vadocaine and diphenhydramine hydrochloride
| Article | Year |
|---|---|
Steady state pharmacokinetics of the new antitussive compound vadocaine hydrochloride.
Topics: Adult; Antitussive Agents; Biotransformation; Electrocardiography; Humans; Male; Piperidines | 1990 |
Effects of lidocaine, codeine and vadocaine hydrochloride on platelet aggregation in human platelet-rich plasma.
Topics: Adenosine Diphosphate; Alprostadil; Antitussive Agents; Bucladesine; Codeine; Female; Humans; In Vitro Techniques; Lidocaine; Male; Piperidines; Platelet Aggregation; Thromboxane B2 | 1988 |
Vadocaine hydrochloride. A novel antitussive compound.
Topics: Animals; Antitussive Agents; Humans; Piperidines | 1988 |
Antitussive action of the new anilide derivative vadocaine hydrochloride compared with codeine phosphate in four animal models.
Topics: Anesthetics, Local; Animals; Antitussive Agents; Cats; Codeine; Cornea; Dogs; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Irritants; Male; Piperidines; Reflex | 1988 |
Studies on the nonspecific central nervous system effects of the novel antitussive compound vadocaine hydrochloride.
Topics: Analgesics; Animals; Anticonvulsants; Antitussive Agents; Barbiturates; Brain; Female; Male; Mice; Motor Activity; Piperidines; Psychomotor Performance; Rats; Rats, Inbred Strains; Reaction Time; Sleep; Time Factors | 1988 |
Comparison of the effects of two opioid antitussives, vadocaine hydrochloride, clobutinol and lidocaine on lung mechanics in guinea-pigs.
Topics: Amino Alcohols; Animals; Antitussive Agents; Blood Pressure; Female; Guinea Pigs; Heart Rate; Hemodynamics; Lidocaine; Lung; Methacholine Compounds; Piperidines; Respiratory Function Tests | 1988 |
Cardiovascular and ventilator effects of vadocaine hydrochloride in urethane-anaesthetized rats and guinea-pigs.
Topics: Anesthesia; Animals; Antitussive Agents; Blood Pressure; Electrocardiography; Guinea Pigs; Heart Rate; Hemodynamics; Injections, Intravenous; Male; Piperidines; Rats; Rats, Inbred Strains; Respiration; Urethane | 1988 |
Comparative studies on the dependence liability of morphine hydrochloride, codeine phosphate and two novel antitussive compounds vadocaine hydrochloride and N-(2',4'-dimethyl-6'-methoxyphenyl)-4-(diethylamine) butanamide hydrochloride in mice.
Topics: Animals; Antitussive Agents; Behavior, Animal; Body Temperature; Body Weight; Codeine; Female; Mice; Morphine; Piperidines; Substance Withdrawal Syndrome; Substance-Related Disorders | 1988 |
Preliminary pharmacokinetics of the new antitussive compound vadocaine hydrochloride in animals.
Topics: Administration, Oral; Animals; Antitussive Agents; Biological Availability; Dogs; Female; Half-Life; Male; Piperidines; Rabbits; Rats | 1988 |
Tissue distribution of the novel antitussive compound vadocaine hydrochloride in white female mice studied by whole-body autoradiography.
Topics: Animals; Antitussive Agents; Autoradiography; Chromatography, Thin Layer; Female; Mice; Piperidines; Tissue Distribution | 1988 |
Pharmacokinetics of graded single doses of the novel antitussive compound vadocaine hydrochloride in healthy male volunteers.
Topics: Adult; Antitussive Agents; Half-Life; Humans; Male; Piperidines; Reference Values | 1988 |
Assessment of the safety margin of vadocaine hydrochloride in man.
Topics: Adult; Antitussive Agents; Blood Pressure; Electrocardiography; Heart Rate; Humans; Male; Piperidines | 1988 |