vadimezan has been researched along with flavone acetic acid in 25 studies
| Studies (vadimezan) | Trials (vadimezan) | Recent Studies (post-2010) (vadimezan) | Studies (flavone acetic acid) | Trials (flavone acetic acid) | Recent Studies (post-2010) (flavone acetic acid) |
|---|---|---|---|---|---|
| 272 | 16 | 101 | 211 | 12 | 9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (68.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atwell, GJ; Baguley, BC; Denny, WA; Li, ZA; Rewcastle, GW | 1 |
| Belluti, F; Bisi, A; Caputo, A; Carrara, M; Gobbi, S; Piazzi, L; Rampa, A; Valenti, P; Zampiron, A | 1 |
| Chen, WH; Deng, YH; Gu, CP; Li, XF; Liu, SW; Yan, GH; Yu, L; Zhou, ZZ | 1 |
| Baguley, BC; Thomsen, LL; Wilson, WR | 1 |
| Baguley, BC; Ching, LM; Joseph, WR | 2 |
| Baguley, BC; Denny, WA; Kestell, P; McKeage, MJ | 1 |
| Baguley, BC; Ching, LM; Joseph, WR; Kestell, P; McKeage, MJ; Zwi, LJ | 1 |
| Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ | 2 |
| Ellis, AG; Kestell, P; Rewcastle, GW; Webster, LK | 1 |
| Baguley, BC; Cliffe, S; Hill, RP; Rutland, M; Taylor, ML; Wilson, WR | 1 |
| Baguley, BC; Cole, G; Li, Z; Thomsen, LL | 1 |
| Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E | 1 |
| Arnold, S; Chaplin, DJ; Watts, ME | 1 |
| Begent, RH; Boden, JA; Boden, R; Boxer, GM; Flynn, AA; Keep, PA; Pedley, RB | 1 |
| Baguley, BC; Kestell, P; Zhuang, L | 1 |
| Phillips, RM | 1 |
| Ching, LM; Eberly, K; Young, HA; Yu, CR | 1 |
| Ching, LM; Kanwar, JR; Kanwar, RK; Krissansen, GW; Pandey, S | 1 |
| Baguley, BC | 1 |
| Horsman, MR; Murata, R | 1 |
| Kovacic, P | 1 |
| Barbera, M; Bisi, A; Caputo, A; Carrara, M; Gobbi, S; Rampa, A; Zampiron, A | 1 |
| Busk, M; Horsman, MR; Iversen, AB | 1 |
2 review(s) available for vadimezan and flavone acetic acid
| Article | Year |
|---|---|
Small-molecule cytokine inducers causing tumor necrosis.
Topics: 5-Hydroxytryptophan; Animals; Antineoplastic Agents; Capillary Permeability; Cytokines; Endothelium, Vascular; Flavonoids; Humans; Interferon-alpha; Mice; Microcirculation; Necrosis; Neoplasms; NF-kappa B; Nitric Oxide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2001 |
Fundamental, electron transfer mechanism by pyrylium-type ions for the anticancer drugs 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA).
Topics: Animals; Antineoplastic Agents; Apoptosis; Electron Transport; Flavonoids; Humans; Molecular Structure; Pyrans; Signal Transduction; Structure-Activity Relationship; Xanthones | 2005 |
23 other study(ies) available for vadimezan and flavone acetic acid
| Article | Year |
|---|---|
Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Indicators and Reagents; Mice; Mice, Inbred Strains; Molecular Structure; Structure-Activity Relationship; Xanthenes; Xanthones | 1991 |
Synthesis and biological evaluation of 3-alkoxy analogues of flavone-8-acetic acid.
Topics: Animals; Drug Screening Assays, Antitumor; Flavonoids; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Macrophages; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Monocytes; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Synthesis, selective cytotoxicities and probable mechanism of action of 7-methoxy-3-arylflavone-8-acetic acids.
Topics: Acetates; Antineoplastic Agents; Cell Line, Tumor; Humans; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2014 |
Nitric oxide: its production in host-cell-infiltrated EMT6 spheroids and its role in tumour cell killing by flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Flavonoids; Mammary Neoplasms, Experimental; Nitric Oxide; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xanthenes; Xanthones | 1992 |
Stimulation of macrophage tumouricidal activity by 5,6-dimethyl-xanthenone-4-acetic acid, a potent analogue of the antitumour agent flavone-8-acetic acid.
Topics: Animals; Antineoplastic Agents; BCG Vaccine; Dose-Response Relationship, Drug; Flavonoids; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Thioglycolates; Tumor Cells, Cultured; Xanthenes; Xanthones | 1992 |
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; T-Lymphocytes; Thymectomy; Xanthenes; Xanthones | 1992 |
Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice.
Topics: Animals; Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flavonoids; Male; Mice; Mice, Inbred Strains; Protein Binding; Xanthenes; Xanthones | 1991 |
Haematological effects in mice of the antitumour agents xanthenone-4-acetic acid, 5,6-dimethyl-xanthenone-4-acetic acid [correction of 5,6-methyl-] and flavone acetic acid.
Topics: Animals; Antineoplastic Agents; Blood; Blood Cells; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Flavonoids; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Xanthenes; Xanthones | 1991 |
Necrosis in non-tumour tissues caused by flavone acetic acid and 5,6-dimethyl xanthenone acetic acid.
Topics: Animals; Antineoplastic Agents; Endometrium; Female; Flavonoids; Lymphoid Tissue; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Thrombosis; Xanthenes; Xanthones | 1990 |
Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
Topics: Animals; Antineoplastic Agents; Bile; Flavonoids; Glucuronates; Glucuronic Acid; In Vitro Techniques; Liver; Male; Perfusion; Protein Binding; Rats; Rats, Sprague-Dawley; Xanthenes; Xanthones | 1995 |
The morphological effects of the anti-tumor agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on the colon 38 mouse tumor.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Apoptosis; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Necrosis; Phosphocreatine; Xanthenes; Xanthones | 1994 |
Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid.
Topics: Aniline Mustard; Animals; Antineoplastic Agents; Drug Synergism; Female; Flavonoids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Regional Blood Flow; Tirapazamine; Triazines; Xanthenes; Xanthones | 1994 |
Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Nitrates; Nitric Oxide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1993 |
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones | 1993 |
Changes in coagulation and permeability properties of human endothelial cells in vitro induced by TNF-alpha or 5,6 MeXAA.
Topics: Antineoplastic Agents; Blood Coagulation; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Flavonoids; Humans; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1996 |
Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Carcinoembryonic Antigen; Colorectal Neoplasms; Combined Modality Therapy; Flavonoids; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radioimmunotherapy; Regional Blood Flow; Serotonin; Tissue Distribution; Transplantation, Heterologous; Xanthenes; Xanthones | 1996 |
Increased plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethylxanthenone-4-acetic acid, vinblastine, and colchicine: relation to vascular effects.
Topics: Animals; Antineoplastic Agents; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin; Time Factors; Vinblastine; Xanthenes; Xanthones | 1997 |
Inhibition of DT-diaphorase (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA): implications for bioreductive drug development.
Topics: Antineoplastic Agents; Aziridines; Cell Survival; Cytochrome Reductases; Cytochrome-B(5) Reductase; Enzyme Inhibitors; Flavonoids; Humans; Indolequinones; Indoles; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Tirapazamine; Triazines; Tumor Cells, Cultured; Vitamin K; Xanthenes; Xanthones | 1999 |
Induction of STAT and NFkappaB activation by the antitumor agents 5,6-dimethylxanthenone-4-acetic acid and flavone acetic acid in a murine macrophage cell line.
Topics: Animals; Antineoplastic Agents; Cell Line; Cycloheximide; DNA-Binding Proteins; Flavonoids; Interferon-beta; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Protein Synthesis Inhibitors; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Xanthenes; Xanthones | 1999 |
Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; B7-1 Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Female; Flavonoids; Gene Dosage; Genetic Therapy; Genetic Vectors; Immunotherapy; Killer Cells, Natural; Lymphocyte Subsets; Lymphoma; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; T-Lymphocytes, Cytotoxic; Thymus Neoplasms; Xanthenes; Xanthones | 2001 |
Combination of vascular targeting agents with thermal or radiation therapy.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Radiation; Flavonoids; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Stilbenes; Temperature; Time Factors; Tumor Cells, Cultured; X-Rays; Xanthenes; Xanthones | 2002 |
The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Screening Assays, Antitumor; Female; Flavonoids; Humans; Lipopolysaccharides; Monocytes; Nitric Oxide; Ovarian Neoplasms; Tumor Necrosis Factor-alpha; Xanthones | 2008 |
Induction of hypoxia by vascular disrupting agents and the significance for their combination with radiation therapy.
Topics: Animals; Antineoplastic Agents; Blood Vessels; Chemoradiotherapy; Diphosphates; Female; Flavonoids; Hypoxia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Oxygen; Stilbenes; X-Ray Therapy; Xanthones | 2013 |