Compounds > vadimezan
Page last updated: 2024-09-03

vadimezan and diclofenac

vadimezan has been researched along with diclofenac in 3 studies

Compound Research Comparison

Studies
(vadimezan)		Trials
(vadimezan)		Recent Studies (post-2010)
(vadimezan)		Studies
(diclofenac)		Trials
(diclofenac)		Recent Studies (post-2010) (diclofenac)
272161018,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomyvadimezan (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ching, LM; Kestell, P; Paxton, JW; Tingle, MD; Zhou, S2
Baguley, BC; Ching, LM; Kestell, P; Paxton, JW; Sutherland, R; Wang, LC; Zhuang, L1

Other Studies

3 other study(ies) available for vadimezan and diclofenac

ArticleYear
In vitro and in vivo kinetic interactions of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Diclofenac; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Protein Binding; Teratogens; Thalidomide; Xanthenes; Xanthones

2001
A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:6

    Topics: Animals; Antineoplastic Agents; Cyproheptadine; Diclofenac; Drug Interactions; Glucuronides; Hydroxylation; Male; Mice; Microsomes, Liver; Rats; Rats, Wistar; Thalidomide; Xanthenes; Xanthones

2001
Enhancement of the action of the antivascular drug 5,6-dimethylxanthenone-4-acetic acid (DMXAA; ASA404) by non-steroidal anti-inflammatory drugs.
    Investigational new drugs, 2009, Volume: 27, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Cyclooxygenase Inhibitors; Diclofenac; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Mice; Mice, Inbred C57BL; Xanthones

2009