Page last updated: 2024-08-16

usnic acid and benzofurans

usnic acid has been researched along with benzofurans in 357 studies

Research

Studies (357)

TimeframeStudies, this research(%)All Research%
pre-199046 (12.89)18.7374
1990's14 (3.92)18.2507
2000's69 (19.33)29.6817
2010's167 (46.78)24.3611
2020's61 (17.09)2.80

Authors

AuthorsStudies
Ding, D; Tan, T; Wu, J; Yan, B; Zhang, M1
Krishna, DR; Mamidi, NV; Ramana, DV1
Kinoshita, Y; Okuyama, E; Umeyama, K; Yamamoto, Y; Yamazaki, M1
Belsner, K; Lauterwein, M; Marre, R; Oethinger, M; Peters, T1
Bacchilega, R; Rafanelli, A; Rafanelli, S; Stanganelli, I1
Abo-Khatwa, AN; al-Jawhari, DA; al-Robai, AA1
Broksa, B; Liptaj, T; Prónayová, N; Sturdíková, M1
Fernandez, E; Ferreira, ME; Fournet, A; Hidalgo, ME; Inchausti, A; Quilhot, W; Rojas de Arias, A; Torres de Ortiz, S; Yaluff, G1
Alesiani, O; Campanella, L; Cardarelli, M; De Cicco Nardone, F; Ercole, P; Rossiello, F; Serino, G1
Chung, GA; Gissurarson, SR; Ingólfsdóttir, K; Skúlason, VG; Vilhelmsdóttir, M1
Kumar, KC; Müller, K1
Marcano, V; Morales Méndez, A; Rodriguez-Alcocer, V1
Battaglia, F; Foti, E; Lopez, R; Malecore, M; Mancuso, S; Masciullo, V; Scambia, G; Scirpa, P; Villa, P1
Proksa, B; Proksová, A1
Rademaker, M1
Bowers, PW; Julian, CG; Paton, JA1
Dayan, FE; Meazza, G; Nanayakkara, NP; Romagni, JG1
Kundu, AB; Parvathavarthini, S; Reddy, MK; Sukumar, E; Vijayakumar, CS; Viswanathan, S1
Enzien, M; Margulis, L1
Kreft, S; Strukelj, B1
Kinoshita, Y; Kurokawa, T; Yamamoto, Y; Yoshimura, I1
Mitchell, JC3
Cocchietto, M; Nimis, PL; Sava, G; Skert, N1
Campanella, L; Delfini, M; Ercole, P; Iacoangeli, A; Risuleo, G1
Masuda, H; Takani, M; Yajima, T; Yamauchi, O1
Ingólfsdóttir, K1
Aradóttir, HA; Ingólfsdóttir, K; Kristmundsdóttir, T; Ogmundsdóttir, HM1
Ceci, R; De Angelis, F; Di Tullio, A; Quaresima, R; Reale, S1
Hyvärinen, M; Koopmann, R; Walter, B1
Bjerke, JW; Elvebakk, A; Lerfall, K1
SODERBERG, U1
VON CZETSCH-LINDENWALD, H1
MOSE, JR2
KONIGSBAUER, H1
CZETSCH-LINDENWALD, H; JURKA, J; KONIGSBAUER, H; MOESE, J1
SHIBATA, S; TAKAHASHI, K; TANAKA, Y1
KILPIO, O1
SCHINDLER, H1
TOMASELLI, R1
PIORKOWSKI, G1
BERGER, JP1
CHIANG, HC; KANEKO, Y; SHIBATA, S; SHIMIZU, H; SHOJI, J; TOKUTAKE, N1
SHOJI, J1
ARAI, A; MIYASHITA, S; OSHIMA, K; TAKAHASHI, K; UEDA, Y1
MIYASHITA, S; TAKAHASHI, K; UEDA, Y1
HONDA, Y; MIYASHITA, S; TAKAHASHI, K1
TROITSKAIA, AD1
PATIALA, J; PATIALA, R1
PLICHET, A1
BRANDER, E; PATIALA, J1
ZATULOVS'KYI, BH2
ALVAREZ BLAZQUEZ, D1
FELDOTT, G; JOHNSON, RB; LARDY, HA1
HASSAL, CH1
BOKAREV, KS; MEL'NIKOV, NN; NAMETKIN, SS1
KALIMA, T; PATIALA, R1
PATIALA, R2
MATSUDAIRA, H; MIURA, Y; NAKAMURA, Y2
HEILALA, P; PATIALA, J; PATIALA, R; SIINTOLA, S1
FUJII, M; HEKI, M; NISHIKAWA, T1
Janthasoot, W; Phrukudom, S; Pongnimitprasert, N; Pramyothin, P; Ruangrungsi, N1
Han, D; Kaplowitz, N; Matsumaru, K; Rettori, D1
Busuttil, RW; Durazo, FA; Farmer, DG; Ghobrial, M; Goldstein, RL; Gordon, S; Han, SH; Kawano, M; Lassman, C; Lee, NP; Saab, S; Saggi, B; Yersiz, H1
KUSCHNER, M; MARSHAK, A1
KLOSA, J1
FAGER, J; MARSHAK, A1
Donelli, G; Francolini, I; Norris, P; Piozzi, A; Stoodley, P1
Alves, AJ; Gonçalves, EC; Honda, NK; Nascimento, SC; Ribeiro-Costa, RM; Santos, NP; Santos-Magalhães, NS; Silva, NH1
Durazo, FA; Kaplowitz, N; Marrero, R; Meyer, D; Neff, GW; Reddy, KR1
Andrade, PP; De Carvalho, EA; Figueiredo, RC; Pereira, EC; Silva, NH1
Bucar, F; Ingólfsdóttir, K; Ogmundsdóttir, H; Schneider, I1
Bjerke, JW; Dahlback, A; Domínguez, E; Elvebakk, A1
Correché, ER; Enriz, RD; Garbarino, J; Gómez-Lechón, MJ; Piovano, M1
Ingólfsdóttir, K; Jónsdóttir, E; Kristmundsdóttir, T; Ogmundsdóttir, HM1
Chang, FY; Hsu, LM; Huang, YS; Lee, SD1
Dong, Y; He, L; Jin, J1
Andersen, RJ; Bombuwela, K; De Silva, D; Karunaratne, V; Kathirgamanathar, S; Williams, DE1
Appleyard, VC; Carneiro-Leão, AM; Mayer, M; Murray, KE; O'Neill, MA; Santos-Magalhães, NS; Thompson, AM1
Dixon, B1
Aslan, A; Bayir, Y; Cakir, A; Halici, M; Kazaz, C; Odabasoglu, F; Suleyman, H1
Andrade, CA; de Melo, CP; Santos-Magalhães, NS1
Morehouse, K; Musser, SM; Roach, JA; Woo, JY1
Burgart, LJ; Kamath, PS; Maple, JT; Sanchez, W1
Li, MY; Liu, HJ; Wang, XP; Zhang, WD; Zhen, L; Zhou, ZT1
Behera, BC; Makhija, U; Sonone, A; Verma, N1
Law, SV; Sheu, M; Simpson, EL; Storrs, FJ1
da Silva Santos, NP; da Silva, JF; da Silva, NH; de Castro, CM; Honda, NK; Nascimento, SC; Pereira, EC; Pontes-Filho, NT; Santos-Magalhães, NS; Wanderley, MS1
Bialczyk, J; Latkowska, E; Lechowski, Z; Pilarski, J1
Elo, H; Matikainen, J; Pelttari, E1
Kytöviita, MM; Neumann, AB; Stark, S1
Koparal, AT; Türk, H; Tüylü, BA1
Ciftçi, IH; Dilek, ON; Esme, H; Solak, O1
Arif, AM; Grange, AH; Grant, DM; Harper, JK; Hess, WM; Hoffman, AM; Kelley-Swift, EG; Mayer, SG; Sovocool, GW; Strobel, GA1
Brunauer, G; Hager, A; Stocker-Wörgötter, E; Türk, R1
MARSHAK, A; RAJAGOPALAN, S; SCHAEFER, WB1
Dailey, RN; Ingram, JT; Montgomery, DL; Raisbeck, MF; Siemion, R; Vasquez, M1
Barboza, P; Falk, A; Green, TK1
Hauck, M; Jürgens, SR1
Candan, M; Cetin, H; Sumbul, H; Tay, T; Tufan-Cetin, O; Turk, AO; Yanikoglu, A2
Davis, JA; Dickmann, LJ; Foti, RS; Greene, RJ; Hill, JJ; Howard, ML; Pearson, JT; Rock, DA; Slatter, JG; Tay, JC; Wahlstrom, JL1
Lee, HK; Oh, H; Park, SM; Seo, C; Sohn, JH; Yim, JH1
Kohn, A; Mathiesen, SD; Praesteng, KE; Sundset, MA1
Bazin, MA; Boustie, J; Corbel, JC; Delcros, JG; Le Lamer, AC; Rouaud, I; Tomasi, S; Uriac, P1
HARTING, J; MARSHAK, A1
SHIBATA, S; UKITA, T1
NELSON, L1
Hauck, M; Huneck, S; Jürgens, SR; Leuschner, C; Willenbruch, K1
Jehlicka, J; Osterrothová, K1
He, LC; Jin, JQ; Li, CQ1
Chollet-Krugler, M; Tomasi, S; Toupet, L; Uriac, P; van de Weghe, P1
Endo, T; Sato, F; Takahagi, T; Yamamoto, Y1
Bondon, A; Legouin, B; Tomasi, S; Toupet, L; Uriac, P; van de Weghe, P1
Hauck, M; Leuschner, C; Willenbruch, K1
Appendino, G; Burlando, B; Pollastro, F; Ranzato, E; Verotta, L; Volante, A1
Cheng, YB; Gu, N; Li, C; Li, XQ; Si, KW; Wei, LL; Yuan, YK1
Anderson, KS; Hawranik, DJ; Simmonds, R; Sorensen, JL1
Aktepe, OC; Altindis, M; Asik, G; Cetinkaya, Z; Ciftci, IH; Kiyildi, N; Ozdemir, M; Safak, B1
Ali, AA; Allaben, WT; Branham, WS; Desai, VG; Fuscoe, JC; Joseph, A; Leakey, JE; Lee, T; Lewis, SM; Moland, CL1
Galetti, FC; Lira, MC; Rolim-Santos, HM; Santos, NP; Santos-Magalhães, NS; Silva, CL; Simioni, AR; Siqueira-Moura, MP; Tabosa Do Egito, ES; Tedesco, AC1
Cheng, YB; Gu, N; Li, C; Li, XQ; Shi, L; Si, KW; Wei, LL; Yuan, YK1
Dias, DA; Urban, S1
Behera, BC; Makhija, U; Sonone, A1
He, X; Hu, Y; Winter, J; Young, GP1
Barboza, PS; Blix, AS; Folkow, LP; Green, TK; Mathiesen, SD; Sundset, MA1
Björnsdóttir, GG; Einarsdóttir, E; Groeneweg, J; Harethardottir, G; Ingólfsdóttir, K; Ogmundsdóttir, HM; Omarsdóttir, S1
BRACK, A; RENZ, J; STOLL, A1
Backor, M; Backorová, M; Ivanova, V; Klemová, K1
Appleyard, VC; Mayer, M; Murray, KE; O'Neill, MA; Rolim-Santos, HM; Santos-Magalhães, NS; Thompson, AM1
Carretero, ME; Crespo, A; de Paz, GA; Gómez-Serranillos, MP; González-Burgos, E; Palomino, OM; Raggio, J1
Antoniolli, AR; Araújo, AA; Bomfim, RR; Estevam, Cdos S; Silva, JA; Thomazzi, SM1
Almeida da Silva, PE; Ramos, DF1
Boehm, F; Kohlhardt-Floehr, C; Lademann, J; Troppens, S; Truscott, TG1
Bačkor, M; Bačkorová, M; Fedoročko, P; Jendželovský, R; Mikeš, J1
Gough, K; Liao, C; Piercey-Normore, MD; Sorensen, JL1
Hardouin-Lerouge, M; Hudhomme, P; Sallé, M1
Backor, M; Dahse, HM; Graefe, U; Ivanova, V1
Albuquerque, RL; Araújo, AA; Bezerra, MS; Bonjardim, LR; Cardoso, JC; Cavalcante, DR; Dantas, MD; Nunes, PS; Quitans, LJ; Serafini, MR; Souza, JC1
Hur, JS; Jeon, HS; Jung, JS; Koh, YJ; Liu, YP; Luo, H; Yamamoto, Y1
Fiel, M; Grewal, P; Mittal, V; Schiano, T; Yellapu, RK1
Beger, RD; Boros, LG; Guo, L; Leakey, JE; Schmitt, TC; Shi, Q; Sonko, BJ1
Fan, X; Jin, T; Lu, X; Tian, Y; Xiao, S; Zhao, Q1
Ehrlich, G; Greenleaf, R; Kathju, S; Kim, S; Miller, MC; Post, JC; Satish, L; Sotereanos, NG; Stoodley, P1
Amankwa-Sakyi, M; O'Donnell, MW; Sahu, SC; Sprando, RL1
Lucarini, R; Mendes-Giannini, MJ; Pires, RH1
Ali, EM; Cox, R; Edwards, HG; Jehlička, J; Page, K; Vítek, P1
Angeli, CB; Katzin, AM; Kimura, EA; Peres, VJ; Sussmann, RA1
Afolayan, AJ; Sultana, N1
Amicosante, G; Bellio, P; Brisdelli, F; Celenza, G; Garbarino, JA; Nicoletti, M; Perilli, M; Piovano, M; Segatore, B; Setacci, D1
Balaure, P; Chifiriuc, MC; Grumezescu, AM; Hristu, R; Lazar, V; Mihaiescu, DE; Saviuc, C; Stanciu, G1
Araújo, AA; da Rocha, RF; dos Santos, JP; Gelain, DP; Moreira, JC; Pasquali, MA; Rabelo, TK; Rybarczyk-Filho, JL; Vasques, LM; Zeidán-Chuliá, F1
Amicosante, G; Bozzi, A; Brisdelli, F; Celenza, G; Garbarino, JA; Nicoletti, M; Perilli, M; Piovano, M; Sellitri, D1
Dai, F; Dong, Y; Liu, M; Lu, B; Luo, J; Song, Y; Yi, Z; Zhai, D; Zhang, J1
Khodyreva, S; Lavrik, O; Luzina, O; Salakhutdinov, N; Sokolov, D; Sukhanova, M; Zakharenko, A; Zakharova, O1
Fan, X; Liu, Q; Lu, X; Wang, Y; Zhao, X1
Behera, BC; Mahadik, N; Morey, M1
O'Donnell, MW; Sahu, SC; Sprando, RL1
Darokar, MP; Gupta, S; Gupta, VK; Pal, A; Singh, A; Singh, SC; Srivastava, PK; Srivastava, SK; Verma, S1
Kosanić, M; Manojlović, N; Ranković, B; Stanojković, T; Vasiljević, P2
Kiselev, OI; Komarova, NI; Luzina, OA; Polovinka, MP; Salakhutdinov, NF; Shtro, AA; Sokolov, DN; Zarubaev, VV1
Bessadottir, M; Egilsson, M; Einarsdottir, E; Magnusdottir, IH; Ogmundsdottir, HM; Ogmundsdottir, MH; Omarsdottir, S1
Bruno, M; Kaiser, M; Monti, D; Romeo, S; Trucchi, B; Verotta, L1
Crocetta, V; Di Bonaventura, G; Di Vincenzo, V; Garbarino, JA; Nicoletti, M; Piovano, M; Pompilio, A; Pomponio, S1
Boustie, J; Coiffard, L; Couteau, C; Legouin, B; Lohézic-Le Dévéhat, F1
Bracht, A; Comar, JF; Moreira, CT; Oliveira, AL; Peralta, RM1
Akkol, EK; Bruno, M; Burlando, B; Keleş, H; Martinotti, S; Ranzato, E; Süntar, I; Trucchi, B; Verotta, L1
Alves, JM; Cunha, WR; de Oliveira, AI; de Oliveira, PF; Leandro, LF; Martins, Sde P; Mastrocola, DF; Moraes, Tda S; Munari, CC; Sato, VL; Tavares, DC; Tozatti, MG1
Crisante, F; D'Ilario, L; Francolini, I; Martinelli, A; Piozzi, A; Taresco, V1
Asplund, J; Bidussi, M; Gauslaa, Y; Larsson, P; Solhaug, KA1
Kale, RK; Nambiar, D; Singh, N; Singh, RP1
Greenhaw, J; Salminen, WF; Shi, Q1
Andrei, E; Andronescu, E; Chifiriuc, MC; Constantinescu, A; Grumezescu, AM; Holban, AM; Lazar, V; Maniu, H; Mogoşanu, GD; Vasile, BS1
Imaoka, M; Jindo, T; Kiyosawa, N; Niino, N; Sayama, A; Yokouchi, Y1
Aslan, A; Aydın, E; Polat, Z; Türkez, H1
Backor, M; Brabec, V; Kasparkova, J; Kozurkova, M; Plsíkova, J; Stepankova, J1
Barboza, P; Brusetti, L; Glad, T; Mackie, RI; Mathiesen, SD; Sundset, MA; Wright, AD1
Guzow-Krzemińska, B; Maciąg-Dorszyńska, M; Węgrzyn, G1
Alan, Y; Aslan, A; Çakır, A; Dal, H; Dığrak, M; Güllüce, M; Karadayı, M; Kazaz, C; Koçer, S; Tümer, M; Uruş, S1
Feng, SC; Ge, ZH; Sun, LY; Xu, JJ; Zhang, HJ; Zhu, DQ1
da Silva, JB; Lins, RD; Nadvorny, D1
Adler, MT; Fazio, AT; Maier, MS1
Bleotu, C; Chifiriuc, CM; Ficai, A; Grumezescu, AM; Grumezescu, V; Holban, AM; Lazar, V; Mogosanu, GD; Socol, G; Truscă, R; Vasile, BS1
Bauer, R; Franzblau, SG; Kaur, A; Kopp, B; Kretschmer, N; Krupitza, G; Páchniková, G; Pauli, GF; Schinkovitz, A; Slaninová, I; Urban, E; Wang, Y; Zehl, M1
He, H; Lv, H; Miao, X; Pan, H; Shang, X; Wang, D; Yang, Z; Zhang, J1
Milovanović, V; Palić, I; Rancić, S; Stanković, M; Stojanović, GS; Stojanović, IZ1
Bakry, A; D'Ilario, L; Francolini, I; Martinelli, A; Piozzi, A; Taresco, V1
Chaleix, V; Champavier, Y; Dieu, A; Gloaguen, V; Mambu, L; Millot, M; Sol, V2
Chen, XY; Chen, ZW; Feng, XX; Lai, XP; Liang, YZ; Liao, JB; Liu, YH; Mo, ZZ; Su, ZQ; Su, ZR; Zhang, X1
Chen, S; Dobrovolsky, VN; Guo, L; Liu, F; Mei, N; Wu, Y; Zhang, Z1
Almeida, JR; Araújo, AA; Gelain, DP; Moreira, JC; Oliveira, AP; Oliveira, RC; Quintans, JS; Quintans-Junior, LJ; Santos, MR; Serafini, MR; White, PA1
El-Naggar, AM; O'Neill, KL; Shrestha, G; St Clair, LL1
Di, LH; Li, J; Liu, WX; Ren, YL1
Crişan, F; Hur, JS; Jeong, MH; Kim, H; Kim, JJ; Kim, KK; Lee, HB; Lee, KY; Moon, C; Nguyen, TT; Oh, S; Yang, Y; Yee, ST; Yoon, S1
Beema Shafreen, RM; Karutha Pandian, S; Muthamil, S; Nithyanand, P2
da Silva, NH; Falcão, EP; Lima, VL; Martins, MC; Melo, AM; Pereira, EC; Silva, LR; Silva, MC1
Kiselev, OI; Luzina, OA; Salakhutdinov, NF; Shtro, AA; Sokolov, DN; Zarubaev, VV1
Richomme, P; Schinkovitz, A1
Bylka, W; Ćwiklińska, K; Galanty, A; Hołderna-Kędzia, E; Kacprzak, K; Studzińska-Sroka, E1
Araújo, AA; de Melo, MG; Gelain, DP; Nunes, PS; Quintans-Júnior, LJ; Rabelo, TK; Santos, MR; Santos, SL; Serafini, MR1
Alves, LC; da Luz, JS; da Silva, LL; da Silva, NH; de Medeiros, PL; de Oliveira, EB; dos Santos, FA; Martins, MC; Silva, EC1
Chen, S; Guo, L; Mei, N; Shi, Q; Tolleson, WH; Wu, Y; Yan, H; Zhang, Z1
Bellusci, M; Boni, A; D'Ilario, L; Francolini, I; Innocenti, C; Martinelli, A; Padella, F; Piozzi, A; Taresco, V1
Chen, Y; Jiang, B; Li, Q; Li, S; Sun, Y; Wei, Q1
Braz-Filho, R; Moreira, AS; Mussi-Dias, V; Vieira, IJ1
Koparal, AT1
Astudillo, C; Gallardo, MJ; Jemiola-Rzeminska, M; Staforelli, JP; Strzalka, K; Suwalsky, M; Villena, F1
Cejkova, A; Kvasnickova, E; Masak, J; Matatkova, O1
Li, J; Liu, F; Sun, C; Sun, J; Wang, X1
Arsic, I; Isakovic, A; Jeremic, I; Savic, S; Tadic, V; Zugic, A1
Choi, KH; Crişan, F; Ha, HH; Hur, JS; Jeong, HG; Jeong, MH; Jeong, TC; Kim, H; Kim, KK; Lee, KY; Nguyen, TT; Yang, Y; Yu, YH1
Albu, MG; Andronescu, E; Chifiriuc, MC; Grumezescu, AM; Holban, AM; Ion, A; Iordache, F; Maniu, H; Rădulescu, D; Rădulescu, M; Surdu, AV; Vasile, BȘ1
Abdel-Hameed, M; Bertrand, RL; Piercey-Normore, MD; Sorensen, JL1
Cheng, Y; Li, C; Li, X; Si, K; Wei, L; Wu, F; Yu, X1
Luzina, OA; Salakhutdinov, NF; Shtro, AA; Sokolov, DN; Zarubaev, VV1
Eparvier, V; Eydoux, C; Guillemot, JC; Litaudon, M; Peyrat, LA; Stien, D1
Cavalcanti, IM; Ferraz-Carvalho, RS; Linhares, LA; Lira-Nogueira, MC; Montenegro, LM; Pereira, MA; Santos-Magalhães, NS1
Araújo, ES; da Costa, MM; da Silva, NH; de Oliveira, HP; Pereira, EC1
Chai, X; Guo, Q; Hu, Z; Li, R; Qu, C; Su, G; Tu, P; Wan, Z; Yang, A; Yu, X1
Chen, S; Couch, L; Guo, L; Mei, N; Ning, B; Qing, T; Ren, Z; Shi, L; Tolleson, WH; Yu, D; Zhang, Z1
Andrade e Silva, ML; Cunhaa, WR; Ferreira, DS; Flauzino, LG; Groppo, M; Januário, AH; Martins, CH; Moraes, Tda S; Pauletti, PM; Tozatti, MG1
Kapoor, S1
Cunha, WR; de Rezende, AA; Machado, NM; Nepomuceno, JC; Spanó, MA; Tavares, DC1
Angelucci, S; Barone, L; Crocetta, V; Di Bonaventura, G; Di Giulio, A; Di Giuseppe, F; Di Ilio, C; Pompilio, A; Pomponio, S; Riviello, A; Sulpizio, M1
Antreich, SJ; Bačkor, M; Goga, M; Lang, I; Weckwerth, W1
Boustie, J; Chakravarty, S; Chollet-Krugler, M; Dévéhat, FL; Maitra, S; Reddy, RG; Tomasi, S; Veeraval, L1
Dyrkheeva, N; Gushchina, I; Koval, O; Lavrik, O; Luzina, O; Nilov, D; Salakhutdinov, N; Švedas, V; Zakharenko, A1
Begemann, G; Draut, H; Rehm, T; Schobert, R1
Delves, M; Dinglasan, RR; King, JG; Mathias, DK; Pastrana-Mena, R; Rajaram, K; Trucchi, B; Verotta, L; Yee, R1
Beland, FA; Chen, T; de Conti, A; Dreval, K; Kindrat, I; Melnyk, S; Pogribny, IP; Shpyleva, S; Yan, J1
Jovanović, O; Petrović, G; Stojanović, G; Stojanović, I; Zlatanović, I; Zrnzević, I1
Borusiewicz, M; Czyż, J; Galanty, A; Karnas, E; Koczurkiewicz, P; Madeja, Z; Michalik, M; Paw, M; Podolak, I; Węgrzyn, M; Wnuk, D1
Kota, A; Sistla, R; Uppuluri, M; Vanga, NR1
Akl, MR; Ebrahim, HY; El Sayed, KA; Elsayed, HE; Hill, RA1
Chen, HM; Chen, JN; Guo, HZ; Lai, XP; Li, YC; Liu, YH; Su, ZQ; Su, ZR; Sun, CY; Xie, JH1
Favero-Longo, SE; Maffei, ME; Matteucci, E; Occhipinti, A; Piervittori, R1
Aguiar Júnior, FC; Aguiar, GM; Ferreira, DK; Marinho, KS; Martins, MC; Pereira, EC; Santos, KR; Santos, NP; Silva, CR; Silva, NH; Silva, TD1
Crespo, A; Divakar, PK; Fernández-Moriano, C; Gómez-Serranillos, MP1
Imaoka, M; Kai, K; Kiyosawa, N; Niino, N; Yokouchi, Y1
Bertrand, M; Boustie, J; Cornevin, L; Ferron, S; Le Pogam, P; Legouin, B; Lohézic-Le Dévéhat, F; Rouaud, I1
Esmaeili, A; Rajaee, S1
Akhanaev, YB; Duisembekov, BA; Glupov, VV; Kryukov, VY; Luzina, OA; Salakhutdinov, NF; Tomilova, OG; Tyurin, MV; Yaroslavtseva, ON1
Fotoran, WL; Katzin, AM; Kimura, EA; Sussmann, RAC1
An, R; Cheng, X; Kwong, S; Li, G; Liu, C; Wang, C; Wang, H; Wang, X; Yang, T1
Bai, H; Gao, L; Li, Y; Ma, T; Song, X; Zhang, Z; Zhao, J; Zheng, Y1
Du, X; Qu, C; Tu, P; Zhang, L; Zhang, X; Zhao, Y; Zheng, J1
Araújo, HDA; Fonseca, CSM; Lima, VLM; Martins, MCB; Melo, AMMA; Silva, LRS; Silva, NH; Siqueira, WN1
Filippov, EV; Filippova, GV; Prokop'ev, IA; Zhanataev, AK1
Chen, X; Gao, H; Geng, X; Pan, W; Qin, G; Tu, J; Wang, J; Zhang, C; Zhang, X; Zhou, B1
Bazarnova, Y; Lyskova, N; Politaeva, N1
Luzina, OA; Salakhutdinov, NF1
Alcaraz-Espinoza, JJ; da Costa, MM; de Oliveira, HP; Dos Santos, MR1
da Silva, PEA; Ramis, IB; Ramos, DF; Reis, AJ; Vianna, JS; Viveiros, M; von Groll, A1
Galanty, A; Koczurkiewicz, P; Pękala, E; Piska, K; Podolak, I; Potaczek, J; Żmudzki, P1
Geng, C; Hua, M; Li, C; Tian, F; Wang, Y; Yuan, X1
Chelobanov, B; Chepanova, A; Dyrkheeva, N; Eurtivong, C; Filimonov, A; Ilina, E; Ilyina, A; Klabenkova, K; Lavrik, O; Luzina, O; Reynisson, J; Salakhutdinov, N; Sokolov, D; Stetsenko, D; Volcho, K; Zafar, A; Zakharenko, A; Zakharova, O1
Cecener, G; Egeli, U; Eryilmaz, IE; Eskiler, GG; Tunca, B; Yurdacan, B1
Cecener, G; Egeli, U; Eryilmaz, IE; Guney Eskiler, G; Tunca, B; Yurdacan, B3
Dyrkheeva, N; Filimonov, A; Gushchina, I; Ilina, E; Kuprushkin, M; Lavrik, O; Luzina, O; Nilov, D; Salakhutdinov, N; Švedas, V; Zakharenko, A; Zakharova, O1
Donelli, G; Francolini, I; Piozzi, A1
Alves, TMA; Cota, BB; de Oliveira, DM; Johann, S; Junker, J; Kolloff, M; Mendes, G; Pereira, CB; Rosa, CA; Rosa, LH; Zani, CL1
Guo, S; Lei, L; Ma, X; Song, B; Song, Y; Su, Y; Yu, Z1
Bae, WK; Choi, YJ; Chung, IJ; Gamage, C; Ha, HH; Hur, JS; Kim, H; Kim, KK; Kim, SK; Lee, JH; Lee, JY; Lee, KH; Paik, MJ; Park, MS; Park, SY; Taş, İ; Yang, Y; Yu, YH; Zhou, R1
Borroni, E; Cirillo, D; Festoso, I; Mazier, D; Monti, D; Romeo, S; Verotta, L1
Büyük, İ; Cansaran-Duman, D; Gür-Dedeoğlu, B; Islakoğlu, YÖ; Kiliç, N1
Chai, XY; Gao, XL; Jiao, SG; Liu, CS; Qu, CH; Tu, PF; Wuken, SN; Yang, XY; Zhang, Q1
Aires, AL; Albuquerque, MCPA; Alves, LC; Araújo, HDA; Brayner, FA; Brito, TGS; Lima, VLM; Martins, MCB; Nascimento, WM; Silva, NH; Silva, TG; Soares, CLR1
Garg, A; Garg, S; Gupta, U; Rani, S; Sahu, NK; Yadav, AK1
Du, Y; Guan, S; Hou, L; Jin, Y; Sun, W; Wang, Q; Xu, H; Zhang, L1
Czarnota, P; Furmanek, Ł; Seaward, MRD1
Alavi, M; Karimi, N1
Antonenko, YN; Khailova, LS; Kotova, EA; Luzina, OA; Nazarov, PA; Nosikova, ES; Rokitskaya, TI; Salakhutdinov, NF1
Filippov, E; Filippova, G; Prokopiev, I; Sleptsov, I; Voronov, I; Zhanataev, A1
de Fatima, A; Fernandes, SA; Horta, LP; Lage, TCA; Modolo, LV; Montanari, RM; Silva, JG1
Beydemir, Ş; Ceylan, H; Demir, Y1
Calarco, P; Ceccarini, MR; Conte, C; Pagano, C; Perioli, L; Primavilla, S; Ricci, M; Scuota, S1
Balanco, JMF; Gabriel, HB; Katzin, AM; Kimura, EA; Sussmann, RAC; Verdaguer, IB1
Darokar, MP; Gupta, VK; Joshi, R; Kumar, P; Kumar, R; Pal, A; Sinha, S1
Cunha, WR; Furtado, RA; Guissone, APP; Lemos, ILL; Machado, NM; Nicolella, HD; Ozelin, SD; Rezende, AAA; Ribeiro, AB; Rinaldi-Neto, F; Silva, LHDD; Spanó, MA; Tavares, DC1
Boustie, J; Charrier, M; Clerc, P; Daugan, C; Fanuel, M; Gadea, A; Le Lamer, AC; Lohézic-Le Devehat, F; Rogniaux, H; Sauvager, A1
Araújo, HDA; C Barroso Martins, M; C P Azevedo Albuquerque, M; Cavalcanti Bezerra, MA; Dos Anjos, JV; Falcão, EPS; Helena M L Ribeiro, M; Lima Aires, A; Melo-Júnior, MR; Menezes Lima, VL; Pereira, EC; Pontes Filho, NT; Raposo Silva, DJ; Saturnino Oliveira, JR; Silva Júnior, JG; Silva, NH1
Guan, L; Huang, M; Liu, D; Wang, S; Xing, K; Zang, J; Zhang, J; Zhao, L1
Altieri, B; Francolini, I; Giansanti, L; Mancini, G; Mauceri, A; Piozzi, A1
Chavasiri, W; Duong, TH; Huynh, TT; Mac, DH; Nguyen, HH; Nguyen, KP; Nguyen, TP; Nguyen, VK; Nguyen, XH; Niamnont, N; Pham, DD; Sichaem, J1
Choi, H; Kang, H; Kim, GJ; Lee, J; Nam, JW; Nam, SJ; Wang, W; Yang, I1
Guo, HY; Jin, C; Jin, CM; Quan, ZS; Shen, QK; Zhang, HM1
Piercey-Normore, MD; Sveshnikova, N; Warren, JM; Yuan, T1
Aires, AL; Albuquerque, MCPA; Alves, LC; Araújo, HDA; Brayner, FA; Lima, VLM; Santos, VHB; Silva, NH1
Cansaran-Duman, D; Tanman, Ü; Yangın, S1
Ayine-Tora, DM; Chand, R; Chepanova, AA; Dyrkheeva, NS; Filimonov, AS; Ilina, ES; Khachatryan, DS; Kolotaev, AV; Kuprushkin, MS; Lavrik, OI; Leung, IKH; Luzina, OA; Patel, J; Reynisson, J; Salakhutdinov, NF; Volcho, KP; Zakharenko, AL; Zakharova, OD1
Aires, AL; Albuquerque, MCPA; Araújo, HDA; Lima, VLM; Silva, NH1
Beaudry, R; Fryday, A; Koptina, AV; LaDuca, RL; Laivenieks, M; Linz, JE; Roze, LV; Schilmiller, AL; Smith, B; Staples, R; Trail, F1
Kumar, K; Mishra, JPN; Singh, RP1
Bangalore, PK; Bollikanda, RK; Choudante, PC; Kantevari, S; Misra, S; Sridhar, B; Sriram, D; Vagolu, SK; Veeragoni, DK1
Kong, LY; Peng, W; Qu, LL; Shi, CJ; Wang, C; Wang, XB; Yang, HL; Zhao, JH1
Chung, HY; Ha, S; Hur, JS; Kim, H; Lee, J; Lee, S; Lee, Y1
Huang, H; Liu, B; Lu, C; Qi, W; Song, S; Zhang, W1
Cheng, X; Chou, G; Huang, Z; Ji, L; Kwong, SP; Lu, B; Shi, L; Wang, C; Wang, H1
Antonenko, YN; Chelombitko, MA; Chernyak, BV; Firsov, AM; Khailova, LS; Kotova, EA; Popova, LB; Rokitskaya, TI1
Hansen, PE; Samuelsen, L; Vang, O1
Cansaran-Duman, D; Değerli, E; Torun, V1
Lawrenson, SB; O'Reilly, RK; Pearce, AK; Rauschenbach, M; Taresco, V1
Battista, S; Bellio, P; Celenza, G; Franceschini, I; Galantini, L; Giansanti, L; Mancini, G1
Khan, F; Kim, YM; Yu, H1
Kan, MU; Prokop'ev, IA1
Fujimoto, K; Hashimoto, K; Kishino, H; Mori, K; Watanabe, K; Yamoto, T1
Cansaran-Duman, D; Özben, RŞ1
da Costa, BL; da Silva, FR; da Silva-Cunha, A; de Castro Oliveira, HM; de Souza Araújo, AA; Lima Santos, NG; Lima, BS; Menezes, GB; Nunes Dourado, LF; Nunes, PS; Palanch Repeke, CE; Silva, RO1
Chepanova, A; Dyrkheeva, N; Filimonov, A; Ilina, E; Lavrik, O; Likhatskaya, G; Luzina, O; Salakhutdinov, N; Zakharenko, A; Zakharova, O1
Kwong, SP; Wang, C1
Chen, D; Chen, L; Dong, J; Geng, R; Gou, H; Liu, J; Peng, H; Wu, W; Yang, X; Zhao, Y1
Boeing, T; Cazarin, CA; Corrêa, R; Dalmagro, AP; Fátima, Â; Fernandes, SA; Gonçalves, AE; Klein-Júnior, LC; Lage, TCA; Lorenzett, TS; Pinto, BC; Silva, LMD; Sobrinho, TUDC; Souza, MM1
de Almeida, GKM; de Sá, LA; de Souza Araujo, AA; Dos Passos Menezes, P; Dos Santos, PH; Lauton-Santos, S; Mesquita, T; Miguel-Dos-Santos, R1
Bousarghin, L; Clément, M; Garnier, A; Maciuk, A; Noël, A; Rouaud, I; Sauvager, A; Tomasi, S; Vásquez-Ocmín, P1
Crespo, A; Dal Grande, F; Divakar, PK; Grewe, F; Lumbsch, HT; Pizarro, D1
Avonto, C; Chittiboyina, AG; Dale, OR; Khan, IA; Khan, SI; Parcher, JF; Wang, M1
Chen, C; Jiang, Q; Li, Y; Xie, H; Xiong, X; Zha, X; Zhang, L1
Kumar, CBM; Pandian, SK; Priya, A; Selvaraj, A; Valliammai, A1
Huang, Z; Ji, L; Kwong, SP; Wang, C1
Chavasiri, W; Devi, AP; Duong, TH; Huynh, BL; Nguyen, HT; Nguyen, NH; Nguyen, TV; Nguyen, VK; Pham, DD; Sichaem, J1
Harjuliarto, R; Maulidiyah, -; Nurdin, M; Sabarwati, SH; Watoni, AH1
Ulus, G1
Baer-Dubowska, W; Kleszcz, R; Krajka-Kuźniak, V; Paluszczak, J1
Jin, CH; Jin, HL; Jin, X; Li, MY; Ma, J; Piao, LX; Ri, M; Sun, TX; Wang, JY; Xing, Y; Xu, GH; Zhang, ZH; Zuo, HX1
Elumalai, P; Lakshmi, S; Sivan, S; Varija Raghu, S1
Antonenko, YN; Kotova, EA; Rokitskaya, TI1
Dyrkheeva, NS; Filimonov, AS; Ilina, ES; Lavrik, OI; Luzina, OA; Malakhova, AA; Medvedev, SP; Reynisson, J; Salakhutdinov, NF; Volcho, KP; Zakharenko, AL; Zakian, SM1
Kaledin, VI; Lavrik, OI; Luzina, OA; Nikolin, VP; Popova, NA; Salakhutdinov, NF; Zakharenko, AL1
Bae, WK; Cho, SH; Chung, IJ; Ha, HH; Kim, DH; Kim, H; Oh, S; Park, MS; Yoo, KH1
Beydemir, Ş; Ceylan, H; Demir, Y; Türkeş, C1
Cielecka-Piontek, J; Galanty, A; Paczkowska-Walendowska, M; Paśko, P; Pękala, E; Podolak, I; Popiół, J; Studzińska-Sroka, E1
Fołta, M; Galanty, A; Krośniak, M; Podolak, I; Węgrzyn, M; Wietrzyk-Pełka, P; Zagrodzki, P1
Cajubá de Britto Lira Nogueira, M; Carvalho da Silva, MDP; Correia de Sousa, LÂ; Costa Silva, BS; da Silva Góes, AJ; da Silva, TG; de Arruda Barbosa, VS; de Siqueira Ferraz Carvalho, R; Dos Santos Aguiar, J; Dos Santos Macedo, DC; Lapa Montenegro Pimentel, LM; Lima Salviano, T; Pereira, MA; Santos Magalhães, NS; Souto, FO1
Ekiert, H; Jafernik, K; Kikowska, M; Klimek-Szczykutowicz, M; Studzińska-Sroka, E; Szopa, A; Thiem, B1
Aires, AL; Albuquerque, MCPA; Araújo, HDA; Coelho, LCBB; Silva Júnior, JGD; Silva, HAMF1
Brileya, K; Chlumsky, O; Demnerova, K; Michova, H; Parker, AE; Purkrtova, S; Smith, HJ; Ulbrich, P; Viktorova, J; Wilking, JN1
Darmawan, A; Maulidiyah, M; Musdalifah, A; Nurdin, M; Salim, OA; Wahyu, W1
Du, S; Gan, D; Gu, X; Han, Y; He, W; Hu, Y; Leng, X; Li, C; Wu, Y; Zhang, X1
Guzow-Krzemińska, B; Hać, A; Herman-Antosiewicz, A; Jąkalski, M; Malinowska, M; Pawlik, A; Pyrczak-Felczykowska, A; Reekie, TA; Ryś, K1
Jayabaskaran, C; Kamat, S; Kumari, M1
Abdelrahman, A; Andresson, OS; Christensen, EA; de Boer, HJ; Gylfason, AE; Heidmarsson, S; Jameson, CJ; Magnusson, KP; Murad, S; Oddsson, S; Olafsdottir, ES; Omarsdottir, S; Oppong-Danquah, E; Pedersen, SV; Snorradottir, BS; Szomek, M; Tasdemir, D; Thorsteinsdottir, M; Wang, X; Xu, M1
Galanty, A; Grudzińska, M; Paśko, P; Podolak, I; Wróbel-Biedrawa, D1
Chandika, P; Heo, SY; Jung, WK; Khan, F; Kim, YM; Yi, M1
Huang, C; Wang, C; Wang, H; Xuan, M1
Gardiner, MG; Gimła, M; Gunawan, GA; Herman-Antosiewicz, A; Reekie, TA1

Reviews

15 review(s) available for usnic acid and benzofurans

ArticleYear
A review on usnic acid, an interesting natural compound.
    Die Naturwissenschaften, 2002, Volume: 89, Issue:4

    Topics: Anti-Bacterial Agents; Benzofurans; Gram-Negative Bacteria; Herbicides; Humans; Lichens; Streptococcus; Tinea Pedis

2002
Usnic acid.
    Phytochemistry, 2002, Volume: 61, Issue:7

    Topics: Analgesics; Animals; Anti-Infective Agents; Antineoplastic Agents; Benzofurans; Humans; Lichens

2002
Molecular clips and tweezers hosting neutral guests.
    Chemical Society reviews, 2011, Volume: 40, Issue:1

    Topics: Acridines; Alkynes; Anthracenes; Benzofurans; Fullerenes; Imidazoles; Models, Chemical; Molecular Conformation; Porphyrins; Rotaxanes

2011
Acute liver failure caused by 'fat burners' and dietary supplements: a case report and literature review.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2011, Volume: 25, Issue:3

    Topics: Adipose Tissue; Adult; Benzofurans; Camellia sinensis; Commiphora; Dietary Supplements; Hepatic Encephalopathy; Humans; Hypolipidemic Agents; Liver Failure, Acute; Liver Transplantation; Monitoring, Physiologic; Obesity; Phytotherapy; Plant Extracts; Plant Gums; Plant Preparations; Tea; Treatment Outcome; Weight Loss

2011
Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review.
    Molecules (Basel, Switzerland), 2014, Sep-12, Volume: 19, Issue:9

    Topics: Antioxidant Response Elements; Antioxidants; Benzofurans; Biphenyl Compounds; Free Radical Scavengers; Humans; Lichens; Neoplasms; Oxidation-Reduction; Oxidative Stress; Picrates

2014
Review of the biological properties and toxicity of usnic acid.
    Natural product research, 2015, Volume: 29, Issue:23

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Benzofurans; Humans; Lichens; Molecular Structure

2015
Chemistry and biological activity of ramalina lichenized fungi.
    Molecules (Basel, Switzerland), 2015, May-19, Volume: 20, Issue:5

    Topics: Animals; Benzofurans; Depsides; Humans; Lichens

2015
Usnic acid and its derivatives for pharmaceutical use: a patent review (2000-2017).
    Expert opinion on therapeutic patents, 2018, Volume: 28, Issue:6

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Benzofurans; Drug Design; Humans; Patents as Topic

2018
Usnic Acid: Potential Role in Management of Wound Infections.
    Advances in experimental medicine and biology, 2019, Volume: 1214

    Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Humans; Lichens; Wound Infection

2019
[Chemical and pharmacological progress on usnic acid and its derivatives].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018, Volume: 43, Issue:19

    Topics: Benzofurans; Biological Products; Lichens

2018
Antifungal activity of lichen compounds against dermatophytes: a review.
    Journal of applied microbiology, 2019, Volume: 127, Issue:2

    Topics: Antifungal Agents; Arthrodermataceae; Benzofurans; Epidermophyton; Lichens; Microsporum; Trichophyton

2019
Review: Usnic acid-induced hepatotoxicity and cell death.
    Environmental toxicology and pharmacology, 2020, Volume: 80

    Topics: Animals; Autophagy; Benzofurans; Cell Death; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Humans; Inflammation; Liver; Mitochondria; Oxidative Phosphorylation; Oxidative Stress

2020
Antiangiogenic properties of lichen secondary metabolites.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:6

    Topics: Angiogenesis Inhibitors; Anti-Infective Agents; Benzofurans; Biological Products; Cyanobacteria; Emodin; Fungi; Furans; Humans; Lichens; Phenylacetates; Salicylates; Xanthones

2021
The Natural Compound Hydrophobic Usnic Acid and Hydrophilic Potassium Usnate Derivative: Applications and Comparisons.
    Molecules (Basel, Switzerland), 2021, Oct-02, Volume: 26, Issue:19

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antiparasitic Agents; Benzofurans; Hydrophobic and Hydrophilic Interactions; Lichens; Potassium

2021
Advances in Research on Bioactivity, Toxicity, Metabolism, and Pharmacokinetics of Usnic Acid In Vitro and In Vivo.
    Molecules (Basel, Switzerland), 2022, Nov-02, Volume: 27, Issue:21

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzofurans; Lichens

2022

Trials

1 trial(s) available for usnic acid and benzofurans

ArticleYear
[A zinc sulfate and usnic acid preparation used as post-surgical adjuvant therapy in genital lesions by Human Papillomavirus].
    Minerva ginecologica, 1999, Volume: 51, Issue:6

    Topics: Adult; Anti-Infective Agents; Astringents; Benzofurans; Chemotherapy, Adjuvant; Colposcopy; Female; Genital Diseases, Female; Humans; Papillomaviridae; Papillomavirus Infections; Postoperative Period; Radiosurgery; Zinc Sulfate

1999

Other Studies

341 other study(ies) available for usnic acid and benzofurans

ArticleYear
[Effect of Cladonia alpestris on Trichomonas vaginalis in vitro].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1995, Volume: 13, Issue:2

    Topics: Animals; Antitrichomonal Agents; Benzofurans; Drugs, Chinese Herbal; In Vitro Techniques; Trichomonas vaginalis

1995
In vitro protein binding and tissue distribution of D(+) usnic acid.
    Drug metabolism and drug interactions, 1995, Volume: 12, Issue:1

    Topics: Animals; Benzofurans; Blood Proteins; Dialysis; Male; Protein Binding; Rabbits; Rats; Rats, Wistar; Serum Albumin, Bovine; Tissue Distribution

1995
Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta.
    Planta medica, 1995, Volume: 61, Issue:2

    Topics: Analgesics; Analgesics, Non-Narcotic; Anisoles; Benzofurans; Chromatography, Thin Layer; Hydroxybenzoates; Magnetic Resonance Spectroscopy; Plants, Medicinal; Spectrophotometry, Infrared

1995
In vitro activities of the lichen secondary metabolites vulpinic acid, (+)-usnic acid, and (-)-usnic acid against aerobic and anaerobic microorganisms.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:11

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Benzofurans; Fungi; Furans; Humans; Lichens; Methicillin Resistance; Microbial Sensitivity Tests; Mupirocin; Phenylacetates; Stereoisomerism

1995
Contact dermatitis from usnic acid in vaginal ovules.
    Contact dermatitis, 1995, Volume: 33, Issue:4

    Topics: Administration, Intravaginal; Adult; Antitrichomonal Agents; Benzofurans; Dermatitis, Allergic Contact; Female; Humans; Patch Tests

1995
Lichen acids as uncouplers of oxidative phosphorylation of mouse-liver mitochondria.
    Natural toxins, 1996, Volume: 4, Issue:2

    Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Anti-Infective Agents; Benzofurans; Ca(2+) Mg(2+)-ATPase; Dose-Response Relationship, Drug; Furans; Hydroxybenzoates; In Vitro Techniques; Male; Mice; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Oxygen Consumption; Phenylacetates; Polarography; Uncoupling Agents

1996
(-)-Usnic acid and its derivatives. Their inhibition of fungal growth and enzyme activity.
    Die Pharmazie, 1996, Volume: 51, Issue:3

    Topics: Antifungal Agents; Benzofurans; Fungi; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests

1996
Activity of compounds isolated from Chilean lichens against experimental cutaneous leishmaniasis.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 116, Issue:1

    Topics: Animals; Antiprotozoal Agents; Benzofurans; Benzoxepins; Depsides; Female; Leishmaniasis, Cutaneous; Lichens; Male; Mice; Mice, Inbred BALB C

1997
Antimitotic effects of usnic acid on different biological systems.
    Cellular and molecular life sciences : CMLS, 1997, Volume: 53, Issue:8

    Topics: Adenocarcinoma; Antifungal Agents; Antineoplastic Agents; Benzofurans; Cell Division; Cells, Cultured; Endometrial Neoplasms; Female; Fusarium; Humans; Mitosis; Nicotiana; Oxygen Consumption; Plants, Toxic; Protoplasts; Saccharomyces cerevisiae; Tumor Cells, Cultured

1997
Antimycobacterial activity of lichen metabolites in vitro.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1998, Volume: 6, Issue:2

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Benzofurans; Depsides; Hydroxybenzoates; Lactones; Lichens; Microbial Sensitivity Tests; Mycobacterium; Salicylates

1998
Lichen metabolites. 2. Antiproliferative and cytotoxic activity of gyrophoric, usnic, and diffractaic acid on human keratinocyte growth.
    Journal of natural products, 1999, Volume: 62, Issue:6

    Topics: Anisoles; Antineoplastic Agents; Arachidonic Acid; Benzoates; Benzofurans; Cell Division; Humans; Hydroxybenzoates; Keratinocytes; L-Lactate Dehydrogenase; Lichens; Lipoxygenase; Tumor Cells, Cultured

1999
Occurrence of usnic acid in Usnea laevis Nylander (lichenized ascomycetes) from the Venezuelan Andes.
    Journal of ethnopharmacology, 1999, Volume: 66, Issue:3

    Topics: Anti-Infective Agents; Benzofurans; Chromatography; Medicine, Traditional; Plant Extracts; Species Specificity; Spectrum Analysis; Venezuela

1999
[Preparation and antineoplastic activity of acylhydrazones of R- and S-usnic acid].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 1999, Volume: 48, Issue:5

    Topics: Antineoplastic Agents; Benzofurans; Humans; Tumor Cells, Cultured

1999
Allergy to lichen acids in a fragrance.
    The Australasian journal of dermatology, 2000, Volume: 41, Issue:1

    Topics: Allergens; Benzofurans; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Humans; Hydroxybenzoates; Lichens; Middle Aged; Patch Tests; Perfume

2000
Frullania dermatitis.
    Contact dermatitis, 2000, Volume: 43, Issue:2

    Topics: Adult; Allergens; Benzofurans; Dermatitis, Allergic Contact; Dermatitis, Occupational; Eczema; Humans; Irritants; Male; Plants; Sesquiterpenes

2000
The phytotoxic lichen metabolite, usnic acid, is a potent inhibitor of plant p-hydroxyphenylpyruvate dioxygenase.
    FEBS letters, 2000, Sep-01, Volume: 480, Issue:2-3

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Benzofurans; Carotenoids; Chlorophyll; Cotyledon; Enzyme Inhibitors; Lichens; Molecular Structure

2000
Anti-inflammatory activity of (+)-usnic acid.
    Fitoterapia, 2000, Volume: 71, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fungi; Gossypium; Granuloma, Foreign-Body; Humans; Ibuprofen; Male; Plants, Medicinal; Rats; Rats, Wistar

2000
Niebla ceruchis from Laguna Figueroa: dimorphic spore morphology and secondary compounds localized in pycnidia and apothecia.
    Microbios, 1988, Volume: 55

    Topics: Benzofurans; Environmental Microbiology; Esters; Lichens; Mexico; Microscopy, Electron; Reproduction; Solanaceae; Spores, Fungal; Symbiosis; Triterpenes

1988
Reversed-polarity capillary zone electrophoretic analysis of usnic acid.
    Electrophoresis, 2001, Volume: 22, Issue:13

    Topics: Anti-Infective Agents; Benzofurans; Electrophoresis, Capillary; Molecular Structure; Time Factors

2001
Influences of nitrogen sources on usnic acid production in a cultured Mycobiont of the lichen Usnea hirta (L.) Wigg.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:8

    Topics: Amino Acids; Anti-Infective Agents; Benzofurans; Culture Media; Lichens; Nitrogen

2001
Allergy to lichens. Allergic contact dermatitis from usnic acid produced by lichenized fungi.
    Archives of dermatology, 1965, Volume: 92, Issue:2

    Topics: Adult; Benzofurans; Dermatitis, Contact; Dermatitis, Occupational; Forestry; Humans; Lichens; Male

1965
Molecular characterization and action of usnic acid: a drug that inhibits proliferation of mouse polyomavirus in vitro and whose main target is RNA transcription.
    Biochimie, 2002, Volume: 84, Issue:4

    Topics: Actins; Animals; Antiviral Agents; Benzofurans; Cell Line; DNA, Viral; Fibroblasts; Lipid Bilayers; Mice; Nuclear Magnetic Resonance, Biomolecular; Polyomavirus; RNA, Messenger; Transcription, Genetic; Transfection; Virion; Virus Replication

2002
Spectroscopic and structural characterization of copper(II) and palladium(II) complexes of a lichen substance usnic acid and its derivatives. Possible forms of environmental metals retained in lichens.
    Journal of inorganic biochemistry, 2002, Jul-25, Volume: 91, Issue:1

    Topics: Anti-Infective Agents; Benzofurans; Circular Dichroism; Copper; Environmental Monitoring; Hydrogen-Ion Concentration; Lichens; Magnetic Resonance Spectroscopy; Molecular Structure; Palladium; X-Ray Diffraction

2002
Solubilization of the lichen metabolite (+)-usnic acid for testing in tissue culture.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:11

    Topics: Analysis of Variance; Benzofurans; Cell Division; Humans; Hydrogen-Ion Concentration; K562 Cells; Lichens; Solubility; Solvents; Thymidine

2002
Investigation by solid-phase microextraction and gas chromatography/mass spectrometry of secondary metabolites in lichens deposited on stone monuments.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:6

    Topics: Benzofurans; Biosensing Techniques; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Italy; Lichens; Molecular Structure; Plant Extracts

2003
Impact of fertilisation on phenol content and growth rate of Cladina stellaris: a test of the carbon-nutrient balance hypothesis.
    Oecologia, 2003, Volume: 134, Issue:2

    Topics: Antifungal Agents; Benzofurans; Hydroxybenzoates; Lichens; Nitrogen; Phosphorus

2003
Effects of ultraviolet radiation and PAR on the content of usnic and divaricatic acids in two arctic-alpine lichens.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2002, Volume: 1, Issue:9

    Topics: Arctic Regions; Benzofurans; Kinetics; Lichens; Light; Ultraviolet Rays

2002
A note on the action of usnic acid on anaesthetized cats.
    Acta physiologica Scandinavica, 1953, Volume: 28, Issue:2-3

    Topics: Acids; Animals; Benzofurans; Blood Glucose; Cats; Cell Respiration; Humans; Metabolism; Respiration

1953
[Chemistry and galenic aspect of usnic acid].
    Arzneimittel-Forschung, 1955, Volume: 5, Issue:9

    Topics: Acids; Benzofurans; Furans

1955
[Antibacterial effects of usnic acid].
    Arzneimittel-Forschung, 1955, Volume: 5, Issue:9

    Topics: Acids; Anti-Bacterial Agents; Bacteria; Benzofurans; Furans

1955
[The treatment of bacterial skin diseases with usnic acid].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1955, Volume: 6, Issue:11

    Topics: Acids; Benzofurans; Furans; Humans; Skin Diseases; Skin Diseases, Bacterial

1955
[Usnic acid as an antibiotic].
    Wiener medizinische Wochenschrift (1946), 1955, Dec-24, Volume: 105, Issue:51-52

    Topics: Acids; Anti-Bacterial Agents; Bacteria; Benzofurans; Furans; Humans

1955
Decomposition of usnic acid. V. Pyrolysis of dihydrousnic acid. (2). Some observations on dihydrousnic acid.
    Pharmaceutical bulletin, 1956, Volume: 4, Issue:1

    Topics: Acids; Benzofurans; Furans

1956
[Antibacterial effects of an usnic acid derivative, usno, and its clinical uses with cases of pyoderma].
    Nordisk hygienisk tidskrift, 1956, Volume: 37, Issue:11-12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Benzofurans; Humans; Pyoderma

1956
[Influence of antibiotics, especially of usnic acid, on tetanus and diphtheria toxins].
    Arzneimittel-Forschung, 1957, Volume: 7, Issue:1

    Topics: Anti-Bacterial Agents; Benzofurans; Diphtheria; Diphtheria Toxin; Furans; Tetanus

1957
[Ingredients of various usnea species with special reference to usnic acid].
    Arzneimittel-Forschung, 1957, Volume: 7, Issue:1

    Topics: Benzofurans; Furans; Lichens; Usnea

1957
[New derivatives of usnic acid used in therapy].
    Il Farmaco; edizione pratica, 1957, Volume: 12, Issue:3

    Topics: Benzofurans; Furans

1957
[Usnic acid as an oral antivirotic].
    Therapie der Gegenwart, 1957, Volume: 96, Issue:8

    Topics: Benzofurans; Furans; Humans; Virus Diseases

1957
[Various bacterial dermatoses & their treatment with usnic acid].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1958, Volume: 9, Issue:11

    Topics: Anti-Bacterial Agents; Benzofurans; Dermatologic Agents; Skin Diseases; Skin Diseases, Bacterial

1958
Decomposition of usnic acid. VI. Studies on the ozonolytic products of O,O-diacetylusnic acid.
    Chemical & pharmaceutical bulletin, 1962, Volume: 10

    Topics: Acids; Benzofurans; Lichens

1962
Decomposition of usnic acid. VII. Pyrolysis of dihydrousnic acid. (3). Isodihydrousnic acid.
    Chemical & pharmaceutical bulletin, 1962, Volume: 10

    Topics: Acids; Benzofurans; Lichens

1962
Usnic acid. II. Methylusnic acid.
    Chemical & pharmaceutical bulletin, 1962, Volume: 10

    Topics: Benzofurans; Heterocyclic Compounds

1962
Usnic acid. IV. Isoanhydromethyldihydrousnic acid.
    Chemical & pharmaceutical bulletin, 1963, Volume: 11

    Topics: Acids; Benzofurans

1963
USNIC ACID. V. SOME DECOMPOSITION REACTION OF METHYL- AND METHYLDIHYDROUSNIC ACIDS. THE REVISED STRUCTURE FOR USNIC ACID ISOMETHOXIDE.
    Chemical & pharmaceutical bulletin, 1963, Volume: 11

    Topics: Acids; Anti-Infective Agents; Benzofurans; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Lichens; Research

1963
[ANTIBIOTIC PREPARATION BINAN (SODIUM SALT OF USNIC ACID) IN THE PREVENTION OF PYODERMA].
    Vestnik dermatologii i venerologii, 1965, Volume: 39

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Benzofurans; Drug Therapy; Humans; Pyoderma; Sodium

1965
ALLERGY TO LICHENS; ALLERGIC CONTACT DERMATITIS FROM USNIC ACID PRODUCED BY LICHENIZED FUNGI.
    Archives of dermatology, 1965, Volume: 92

    Topics: Benzofurans; Dermatitis, Allergic Contact; Dermatitis, Contact; Fungi; Humans; Hypersensitivity; Lichens; Occupational Diseases; Pathology

1965
1-Usnic acid and observations on its effect in human tuberculosis.
    Annales medicinae experimentalis et biologiae Fenniae, 1954, Volume: 32, Issue:8

    Topics: Benzofurans; Tuberculosis; Tuberculosis, Pulmonary

1954
[Usnic acid from lichens in therapy of tuberculosis].
    La Presse medicale, 1955, Mar-05, Volume: 63, Issue:17

    Topics: Acids; Benzofurans; Furans; Humans; Lichens; Tuberculosis; Tuberculosis, Pulmonary

1955
1-Usnic acid, dihydrostreptomycin, and their combination; therapeutic effect in guinea-pig tuberculosis as revealed by the omental index.
    Annales medicinae experimentalis et biologiae Fenniae, 1954, Volume: 32, Issue:3

    Topics: Acids; Benzofurans; Dihydrostreptomycin Sulfate; Furans; Guinea Pigs; Streptomycin; Tuberculosis

1954
[Effect of usnic acid on Mycobacterium tuberculosis and on experimental tuberculosis].
    Mikrobiolohichnyi zhurnal, 1954, Volume: 16, Issue:2

    Topics: Benzofurans; Furans; Mycobacterium tuberculosis; Tuberculosis

1954
[In vitro studies on the effect of usnic acid on causative agents of bacterioses in plants].
    Mikrobiolohichnyi zhurnal, 1954, Volume: 16, Issue:3

    Topics: Bacteria; Benzofurans; Furans; In Vitro Techniques; Plants

1954
[Intralymphatic therapy of tuberculosis].
    Medicamenta, 1950, Jul-01, Volume: 8, Issue:184

    Topics: Benzofurans; Streptomycin; Tuberculosis

1950
The mode of action of the antibiotic, usnic acid.
    Archives of biochemistry, 1950, Volume: 28, Issue:3

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzofurans; Dermatologic Agents; Humans

1950
The antibacterial activity of usnic acid and related compounds.
    Experientia, 1950, Dec-15, Volume: 6, Issue:12

    Topics: Anti-Bacterial Agents; Benzofurans

1950
[Synthesis of certain alkoxyhaloidphenoxyusnic acids and their derivatives].
    Doklady Akademii nauk SSSR, 1951, Mar-21, Volume: 77, Issue:3

    Topics: Benzofurans

1951
[On the effect of usnic acid in vivo].
    Le Progres medical, 1951, Feb-24, Volume: 79, Issue:4

    Topics: Benzofurans; Dermatology; Humans; Tuberculosis

1951
Cutaneous tuberculosis treated with usnic acid.
    Acta dermato-venereologica, 1951, Volume: 31, Issue:3

    Topics: Benzofurans; Humans; Skin; Tuberculosis; Tuberculosis, Cutaneous

1951
[Mode of action of usnic acid on bacteria].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1951, Apr-30, Volume: 232, Issue:18

    Topics: Bacteria; Benzofurans; Growth; Humans

1951
[Effect of 1-usnic acid on experimental tuberculosis of the guinea-pig; review on the antibiotic properties of lichens in general].
    Annales medicinae experimentalis et biologiae Fenniae, 1950, Volume: 28, Issue:3

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzofurans; Dermatologic Agents; Guinea Pigs; Lichens; Tuberculosis

1950
[The mode of action of usnic acid against bacteria].
    Bulletin de la Societe de chimie biologique, 1951, Volume: 33, Issue:10

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacteria; Benzofurans; Escherichia coli; Micrococcus

1951
Experimental studies in the treatment of tetanus and on a case of tetanus treated with usnic acid.
    Japanese journal of medical science & biology, 1952, Volume: 5, Issue:2

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzofurans; Dermatologic Agents; Plants; Tetanus; Tetanus Toxoid

1952
Hepatotoxic effect of (+)usnic acid from Usnea siamensis Wainio in rats, isolated rat hepatocytes and isolated rat liver mitochondria.
    Journal of ethnopharmacology, 2004, Volume: 90, Issue:2-3

    Topics: Animals; Benzofurans; Cells, Cultured; Hepatocytes; Liver; Male; Mitochondria, Liver; Rats; Rats, Wistar; Usnea

2004
Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress.
    Biochemical pharmacology, 2004, Feb-01, Volume: 67, Issue:3

    Topics: Adenosine Triphosphate; Animals; Anti-Infective Agents; Antioxidants; Benzofurans; Cell Survival; Cells, Cultured; Drug Interactions; Glutathione; Hepatocytes; Hydrogen Peroxide; Mice; Mitochondria, Liver; Necrosis; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Respiration

2004
Fulminant liver failure due to usnic acid for weight loss.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:5

    Topics: Adult; Benzofurans; Dietary Supplements; Female; Follow-Up Studies; Humans; Liver Failure; Liver Transplantation; Obesity; Risk Assessment; Weight Loss

2004
Application of usnic acid to a case of lupus vulgaris.
    Annales medicinae experimentalis et biologiae Fenniae, 1949, Volume: 27, Issue:2

    Topics: Acids; Benzofurans; Humans; Lupus Vulgaris

1949
The action of streptomycin and usnic acid on the development of tuberculosis in guinea pigs.
    Public health reports (Washington, D.C. : 1896), 1950, Feb-03, Volume: 65, Issue:5

    Topics: Acids; Animals; Benzofurans; Guinea Pigs; Streptomycin; Tuberculosis

1950
[A new lichenic antibiotic].
    Die Pharmazie, 1950, Volume: 5, Issue:6

    Topics: Anti-Bacterial Agents; Benzofurans; Dermatologic Agents; Humans; Lichens

1950
Prevention of nuclear fusion and mitosis and inhibition of desoxyribonuclease by d-usnic acid.
    Journal of cellular and comparative physiology, 1950, Volume: 35, Issue:3

    Topics: Benzofurans; Cells; Deoxyribonucleases; Mitosis; Nuclear Fusion

1950
Usnic acid, a natural antimicrobial agent able to inhibit bacterial biofilm formation on polymer surfaces.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Adhesion; Benzofurans; Biofilms; Green Fluorescent Proteins; Microscopy, Confocal; Polymers; Polyurethanes; Staphylococcus aureus; Surface Properties

2004
In vitro and in vivo properties of usnic acid encapsulated into PLGA-microspheres.
    Journal of microencapsulation, 2004, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Agents; Benzofurans; Cell Proliferation; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Lactic Acid; Liver; Male; Mice; Mice, Inbred Strains; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sarcoma 180

2004
Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid.
    Journal of hepatology, 2004, Volume: 41, Issue:6

    Topics: Adult; Benzofurans; Chemical and Drug Induced Liver Injury; Diet, Reducing; Dietary Supplements; Drugs, Chinese Herbal; Ephedra sinica; Female; Humans; Male; Middle Aged; Obesity; Plant Preparations

2004
Effect of usnic acid from the lichen Cladonia substellata on Trypanosoma cruzi in vitro: an ultrastructural study.
    Micron (Oxford, England : 1993), 2005, Volume: 36, Issue:2

    Topics: Animals; Anti-Infective Agents; Antiprotozoal Agents; Benzofurans; Lichens; Macrophages, Peritoneal; Mice; Microscopy, Electron; Mitochondria; Trypanosoma cruzi

2005
Anti-proliferative lichen compounds with inhibitory activity on 12(S)-HETE production in human platelets.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2004, Volume: 11, Issue:7-8

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4-Butyrolactone; Benzoates; Benzofurans; Blood Platelets; Depsides; Emodin; Humans; In Vitro Techniques; Lactones; Lichens; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Structure; Resorcinols; Salicylates

2004
Seasonal trends in usnic acid concentrations of Arctic, alpine and Patagonian populations of the lichen Flavocetraria nivalis.
    Phytochemistry, 2005, Volume: 66, Issue:3

    Topics: Arctic Regions; Argentina; Ascomycota; Benzofurans; Europe; Seasons; Time Factors

2005
Cytotoxic and apoptotic effects on hepatocytes of secondary metabolites obtained from lichens.
    Alternatives to laboratory animals : ATLA, 2004, Volume: 32, Issue:6

    Topics: Animals; Antarctic Regions; Apoptosis; Benzoates; Benzofurans; Carboxylic Acids; Caspase 3; Caspases; Depsides; Enzyme Activation; Flow Cytometry; Hepatocytes; Hydroxybenzoates; Lactones; Lichens; Male; Rats; Rats, Sprague-Dawley

2004
Solubilization of poorly soluble lichen metabolites for biological testing on cell lines.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2005, Volume: 24, Issue:5

    Topics: Benzofurans; Cell Line; Fumarates; Hydroxybenzoates; Lichens; Solubility; Thymidine

2005
'Fat burner' herb, usnic acid, induced acute hepatitis in a family.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:7

    Topics: Acute Disease; Adult; Anti-Infective Agents; Benzofurans; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Humans; Plants, Medicinal; Weight Loss

2005
[The study on skin wound healing promoting action of sodium usnic acid].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:2

    Topics: Administration, Topical; Animals; Benzofurans; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Female; Fibroblasts; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Skin; Usnea; Wound Healing

2005
Beta-orcinol depsidones from the lichen Usnea sp. from Sri Lanka.
    Natural product research, 2005, Volume: 19, Issue:7

    Topics: Animals; Benzofurans; Insect Control; Isoptera; Lactones; Sri Lanka; Trees; Usnea

2005
Usnic acid: a non-genotoxic compound with anti-cancer properties.
    Anti-cancer drugs, 2005, Volume: 16, Issue:8

    Topics: Antineoplastic Agents; Benzofurans; Breast Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oxidative Stress; Phosphorylation; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2005
Liking lichens.
    The Lancet. Infectious diseases, 2005, Volume: 5, Issue:9

    Topics: Animals; Anti-Infective Agents; Benzofurans; Food Chain; Food, Organic; Humans; Lichens; Probiotics

2005
Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in rats.
    Journal of ethnopharmacology, 2006, Jan-03, Volume: 103, Issue:1

    Topics: Animals; Antioxidants; Benzofurans; Cytoprotection; Gastric Mucosa; Glutathione Peroxidase; Indomethacin; Male; Neutrophil Infiltration; Nitric Oxide; Peroxidase; Rats; Rats, Wistar; Stomach Ulcer; Superoxide Dismutase

2006
Thermodynamic characterization of the prevailing molecular interactions in mixed floating monolayers of phospholipids and usnic acid.
    Journal of colloid and interface science, 2006, Jun-01, Volume: 298, Issue:1

    Topics: Benzofurans; Entropy; Membranes, Artificial; Phospholipids; Pressure; Surface Tension

2006
Determination of usnic acid in lichen toxic to elk by liquid chromatography with ultraviolet and tandem mass spectrometry detection.
    Journal of agricultural and food chemistry, 2006, Apr-05, Volume: 54, Issue:7

    Topics: Acetone; Acetonitriles; Animals; Benzofurans; Chromatography, High Pressure Liquid; Deer; Lichens; Solubility; Spectrometry, Mass, Electrospray Ionization; Wyoming

2006
Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid.
    Mayo Clinic proceedings, 2006, Volume: 81, Issue:4

    Topics: Adult; Antitrichomonal Agents; Benzofurans; Dietary Supplements; Female; Follow-Up Studies; Humans; Liver Failure, Acute; Liver Transplantation; Male

2006
[Plasmid elimination effect of usnic acid on antibiotic-resistant Staphylococcus aureus].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:1

    Topics: Anti-Bacterial Agents; Benzofurans; Drug Resistance, Bacterial; Electrophoresis, Agar Gel; R Factors; Staphylococcus aureus; Time Factors

2006
Experimental studies on the growth and usnic acid production in "lichen"Usnea ghattensis in vitro.
    Microbiological research, 2006, Volume: 161, Issue:3

    Topics: Benzofurans; Culture Media; Polyethylene Glycols; Sucrose; Symbiosis; Time Factors; Usnea

2006
Allergic contact dermatitis from a natural deodorant: a report of 4 cases associated with lichen acid mix allergy.
    Journal of the American Academy of Dermatology, 2006, Volume: 55, Issue:2

    Topics: Adult; Antifungal Agents; Benzofurans; Deodorants; Dermatitis, Allergic Contact; Humans; Lichens; Male; Middle Aged; Plant Extracts

2006
Nanoencapsulation of usnic acid: An attempt to improve antitumour activity and reduce hepatotoxicity.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2006, Volume: 64, Issue:2

    Topics: Animals; Benzofurans; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Disease Progression; Drug Compounding; Injections, Intraperitoneal; Lactic Acid; Liver; Male; Mice; Nanostructures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sarcoma 180; Survival Analysis

2006
Photosynthesis and water relations in tomato plants cultivated long-term in media containing (+)-usnic acid.
    Journal of chemical ecology, 2006, Volume: 32, Issue:9

    Topics: Benzofurans; Carotenoids; Chlorophyll; Gases; Light; Photosynthesis; Plant Leaves; Plant Transpiration; Solanum lycopersicum; Water

2006
Potent activity of the lichen antibiotic (+)-usnic acid against clinical isolates of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus.
    Die Naturwissenschaften, 2007, Volume: 94, Issue:6

    Topics: Anti-Infective Agents; Benzofurans; Drug Resistance; Enterococcus; Lichens; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Vancomycin

2007
The phenolic compounds in Cladonia lichens are not antimicrobial in soils.
    Oecologia, 2007, Volume: 152, Issue:2

    Topics: Anti-Bacterial Agents; Benzoates; Benzofurans; Lichens; Rain; Soil; Soil Microbiology; Water

2007
In vitro cytotoxic activities of (+)-usnic acid and (-)-usnic acid on V79, A549, and human lymphocyte cells and their non-genotoxicity on human lymphocytes.
    Natural product research, 2006, Volume: 20, Issue:14

    Topics: Animals; Antineoplastic Agents; Benzofurans; Cell Line; Cell Line, Tumor; Cricetinae; Fibroblasts; Formazans; Humans; Lichens; Lymphocytes; Male; Micronucleus Tests; Mutagenicity Tests; Stereoisomerism; Tetrazolium Salts

2006
[Investigation of the germicidal effect of usnic acid, betadine, savlosol, and desderman on the protoscolexes of lung hydatid cysts].
    Turkiye parazitolojii dergisi, 2007, Volume: 31, Issue:2

    Topics: Animals; Anti-Infective Agents; Benzofurans; Cetrimonium; Cetrimonium Compounds; Chlorhexidine; Echinococcosis; Echinococcus; Humans; Lung; Povidone-Iodine

2007
Purification, identification and activity of phomodione, a furandione from an endophytic Phoma species.
    Phytochemistry, 2008, Volume: 69, Issue:4

    Topics: Actinidiaceae; Ascomycota; Basidiomycota; Benzofurans; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Molecular Structure; Oomycetes; Staphylococcus

2008
Production and bioactivity of common lichen metabolites as exemplified by Heterodea muelleri (Hampe) Nyl.
    Journal of chemical ecology, 2008, Volume: 34, Issue:2

    Topics: Anisoles; Ascomycota; Benzofurans; Chlorophyta; Hydroxybenzoates; Lichens; Phthalic Acids

2008
Antibacterial activity of d-usnic acid and related compounds on M. tuberculosis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1949, Volume: 70, Issue:4

    Topics: Anti-Bacterial Agents; Bacillus; Benzofurans; Mycobacterium tuberculosis; Tuberculosis

1949
Toxicity of the lichen secondary metabolite (+)-usnic acid in domestic sheep.
    Veterinary pathology, 2008, Volume: 45, Issue:1

    Topics: Animals; Benzofurans; Female; Lichens; Muscle, Skeletal; Plant Poisoning; Sheep; Sheep Diseases

2008
Quantitative determination of secondary metabolites in Cladina stellaris and other lichens by micellar electrokinetic chromatography.
    Journal of chromatography. A, 2008, Feb-22, Volume: 1182, Issue:1

    Topics: Benzoates; Benzofurans; Chromatography, Micellar Electrokinetic Capillary; Hydroxybenzoates; Lichens; Molecular Structure; Reproducibility of Results

2008
Usnic acid controls the acidity tolerance of lichens.
    Environmental pollution (Barking, Essex : 1987), 2008, Volume: 156, Issue:1

    Topics: Air Pollutants; Benzofurans; Hydrogen-Ion Concentration; Lichens; Models, Biological; Species Specificity; Sulfur Dioxide

2008
Insecticidal activity of major lichen compounds, (-)- and (+)-usnic acid, against the larvae of house mosquito, Culex pipiens L.
    Parasitology research, 2008, Volume: 102, Issue:6

    Topics: Animals; Benzofurans; Culex; Insecticides; Larva; Lethal Dose 50; Lichens; Molecular Structure; Survival Analysis

2008
Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:3

    Topics: Benzofurans; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Liver Diseases; Microsomes, Liver; Models, Molecular; Protein Binding; Risk Factors; Substrate Specificity

2008
Usimines A-C, bioactive usnic acid derivatives from the Antarctic lichen Stereocaulon alpinum.
    Journal of natural products, 2008, Volume: 71, Issue:4

    Topics: Antarctic Regions; Benzofurans; Humans; Lichens; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Protein Tyrosine Phosphatase, Non-Receptor Type 1

2008
Eubacterium rangiferina, a novel usnic acid-resistant bacterium from the reindeer rumen.
    Die Naturwissenschaften, 2008, Volume: 95, Issue:8

    Topics: Animals; Anti-Infective Agents; Benzofurans; Clostridium; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Eubacterium; Phylogeny; Reindeer; RNA, Ribosomal; Rumen; Salicylates

2008
Synthesis and cytotoxic activities of usnic acid derivatives.
    Bioorganic & medicinal chemistry, 2008, Jul-15, Volume: 16, Issue:14

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzofurans; Carrier Proteins; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Humans; Mice; Polyamines; Structure-Activity Relationship

2008
Inhibition of cleavage and P32 uptake in Arbacia by d-usnic acid.
    Journal of cellular and comparative physiology, 1948, Volume: 31, Issue:3

    Topics: Animals; Arbacia; Benzofurans; Cytokinesis; Phosphorus; Phosphorus Compounds; Radioisotopes

1948
Relation between chemical constitutions and antibacterial effects of usnic acid and its derivatives.
    Japanese journal of medicine, 1948, Volume: 1, Issue:2

    Topics: Anti-Bacterial Agents; Benzofurans

1948
Usnic acid, an antibiotic, and sperm metabolism.
    The Biological bulletin, 1948, Volume: 95, Issue:2

    Topics: Anti-Bacterial Agents; Benzofurans; Humans; Male; Spermatozoa

1948
Dissociation and metal-binding characteristics of yellow lichen substances suggest a relationship with site preferences of lichens.
    Annals of botany, 2009, Volume: 103, Issue:1

    Topics: Anthraquinones; Benzofurans; Carboxylic Acids; Copper; Hydrogen-Ion Concentration; Iron; Lactones; Lichens; Magnesium; Manganese; Metals; Spectrophotometry, Ultraviolet; Zinc

2009
Raman spectroscopic identification of usnic acid in hydrothermal minerals as a potential Martian analogue.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 73, Issue:3

    Topics: Benzofurans; Calcium Carbonate; Calcium Sulfate; Crystallization; Exobiology; Extraterrestrial Environment; Mars; Minerals; Spectrum Analysis, Raman

2009
Down-regulatory effect of usnic acid on nuclear factor-kappaB-dependent tumor necrosis factor-alpha and inducible nitric oxide synthase expression in lipopolysaccharide-stimulated macrophages RAW 264.7.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:12

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Benzofurans; Cell Line; Cell Survival; Down-Regulation; Gene Expression Regulation; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Necrosis Factor-alpha; Usnea

2008
Preparation and characterization of copper(II) and nickel(II) complexes of a new chiral salen ligand derived from (+)-usnic acid.
    Dalton transactions (Cambridge, England : 2003), 2008, Dec-14, Issue:46

    Topics: Benzofurans; Copper; Ethylenediamines; Ligands; Nickel; Organometallic Compounds; Stereoisomerism

2008
Lichen photobionts show tolerance against lichen acids produced by lichen mycobionts.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:12

    Topics: Acids, Carbocyclic; Benzofurans; Cells, Cultured; Chlorophyll; Electron Transport; Fluorescence; Lichens; Photosynthesis; Photosystem II Protein Complex; Plant Cells; Plant Development; Plants

2008
Novel chiral molecular tweezer from (+)-usnic acid.
    Organic letters, 2009, Feb-05, Volume: 11, Issue:3

    Topics: Benzofurans; Binding Sites; Crystallography, X-Ray; Cyclohexanes; Fluorenes; Heterocyclic Compounds, 4 or More Rings; Models, Molecular; Molecular Conformation; Molecular Structure; Stereoisomerism

2009
Lichen substances prevent lichens from nutrient deficiency.
    Journal of chemical ecology, 2009, Volume: 35, Issue:1

    Topics: Benzofurans; Biological Transport; Copper; Depsides; Lichens; Manganese

2009
Antiproliferative effects on tumour cells and promotion of keratinocyte wound healing by different lichen compounds.
    Planta medica, 2009, Volume: 75, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Benzoates; Benzofurans; Cell Line, Tumor; Cell Proliferation; Female; Furans; Humans; Hydroxybenzoates; Keratinocytes; Lactones; Lichens; Neoplasms; Phenylacetates; Phytotherapy; Plant Extracts; Salicylates; Wound Healing

2009
[In vitro effect of (+)-usnic acid on Toxoplasma gondii tachyzoites].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2008, Dec-30, Volume: 26, Issue:6

    Topics: Animals; Benzofurans; Cells, Cultured; In Vitro Techniques; Mice; Mice, Inbred Strains; Rats; Spiramycin; Toxoplasma; Toxoplasmosis, Animal

2008
The chemoenzymatic synthesis of usnic acid.
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Anti-Infective Agents; Benzofurans; Chemistry, Organic; Horseradish Peroxidase; Lichens; Models, Chemical; Oxygen

2009
In vitro anti-Helicobacter pylori activity of usnic acid.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:7

    Topics: Anti-Bacterial Agents; Benzofurans; Clarithromycin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Helicobacter pylori; Humans; Microbial Sensitivity Tests; Usnea

2009
Effect of (+)-usnic acid on mitochondrial functions as measured by mitochondria-specific oligonucleotide microarray in liver of B6C3F1 mice.
    Mitochondrion, 2009, Volume: 9, Issue:2

    Topics: Animals; Benzofurans; Energy Metabolism; Female; Gene Expression Profiling; Liver; Metabolic Networks and Pathways; Mice; Mitochondria; Oligonucleotide Array Sequence Analysis; Uncoupling Agents

2009
In vitrouptake and antimycobacterial activity of liposomal usnic acid formulation.
    Journal of liposome research, 2009, Volume: 19, Issue:1

    Topics: Animals; Antitubercular Agents; Benzofurans; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Liposomes; Macrophages; Mice; Mycobacterium tuberculosis; Tuberculosis

2009
[Oral acute toxicity of (+)-usnic acid in mice and its cytotoxicity in rat cardiac fibroblasts].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:8

    Topics: Administration, Oral; Animals; Benzofurans; Fibroblasts; Lethal Dose 50; Mice; Myocardium; Rats; Stereoisomerism

2009
Phytochemical investigation of the Australian lichens Ramalina glaucescens and Xanthoria parietina.
    Natural product communications, 2009, Volume: 4, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Australia; Bacteria; Benzofurans; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Fungi; Leukemia P388; Lichens; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization

2009
Protoplast isolation from cultured lichen Usnea ghattensis, their fusion with protoplasts of Aspergillus nidulans, fusant regeneration and production of usnic acid.
    Folia microbiologica, 2009, Volume: 54, Issue:5

    Topics: Aspergillus nidulans; Benzofurans; Biomass; Cell Fusion; Cells, Cultured; Protoplasts; Regeneration; Usnea

2009
Anti-mutagenic lichen extract has double-edged effect on azoxymethane-induced colorectal oncogenesis in C57BL/6J mice.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Animals; Antimutagenic Agents; Apoptosis; Azo Compounds; Benzofurans; Body Weight; Carcinogens; Cell Proliferation; Colon; Colonic Neoplasms; DNA Damage; Intestinal Mucosa; Lichens; Longevity; Male; Mice; Mice, Inbred C57BL; Plant Extracts

2010
Microbial degradation of usnic acid in the reindeer rumen.
    Die Naturwissenschaften, 2010, Volume: 97, Issue:3

    Topics: Animal Feed; Animals; Benzofurans; Cecum; Colon; Digestion; Ecosystem; Feces; Gastrointestinal Tract; Intestine, Small; Kidney; Lichens; Liver; Male; Norway; Reindeer; Rumen; Ultraviolet Rays

2010
Cellular mechanisms of the anticancer effects of the lichen compound usnic acid.
    Planta medica, 2010, Volume: 76, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Benzimidazoles; Benzofurans; Breast Neoplasms; Carbocyanines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; Lichens; Membrane Potential, Mitochondrial; Necrosis; Pancreatic Neoplasms; Phytotherapy; Plant Extracts

2010
The antibacterial effect of usnic acid on mycobacteria and other microorganisms.
    Experientia, 1947, Mar-15, Volume: 3, Issue:3

    Topics: Anti-Infective Agents; Bacteria; Benzofurans; Humans

1947
Comparison of the phytotoxic effects of usnic acid on cultures of free-living alga Scenedesmus quadricauda and aposymbiotically grown lichen photobiont Trebouxia erici.
    Journal of chemical ecology, 2010, Volume: 36, Issue:4

    Topics: Anti-Infective Agents; Benzofurans; Biological Evolution; Lichens; Scenedesmus; Symbiosis

2010
Does usnic acid affect microtubules in human cancer cells?
    Brazilian journal of biology = Revista brasleira de biologia, 2010, Volume: 70, Issue:3

    Topics: Antimitotic Agents; Antineoplastic Agents; Benzofurans; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Lung Neoplasms; Microtubules; Paclitaxel; Vincristine

2010
HPLC isolation of antioxidant constituents from Xanthoparmelia spp.
    Journal of pharmaceutical and biomedical analysis, 2010, Oct-10, Volume: 53, Issue:2

    Topics: Antioxidants; Benzofurans; Cell Line, Tumor; Cell Survival; Chromatography, Reverse-Phase; Drug Screening Assays, Antitumor; Free Radical Scavengers; Heterocyclic Compounds, 4 or More Rings; Humans; Lactones; Lichens; Oxepins; Plant Extracts; Salicylates

2010
Pharmacological properties of lichen Cladonia clathrata.
    Pharmaceutical biology, 2010, Volume: 48, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Ascomycota; Benzofurans; Biphenyl Compounds; Carrageenan; Drug Evaluation, Preclinical; Lichens; Mice; Motor Activity; Neutrophil Infiltration; Pain Measurement; Picrates; Rats; Rats, Wistar

2010
Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria.
    Pharmaceutical biology, 2010, Volume: 48, Issue:3

    Topics: Anti-Bacterial Agents; Benzofurans; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ionophores; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Tuberculosis, Multidrug-Resistant; Verapamil

2010
Prooxidant and antioxidant behaviour of usnic acid from lichens under UVB-light irradiation--studies on human cells.
    Journal of photochemistry and photobiology. B, Biology, 2010, Oct-05, Volume: 101, Issue:1

    Topics: Antioxidants; Apoptosis; Ascomycota; Benzofurans; Humans; Jurkat Cells; Lichens; Oxidants; Reactive Oxygen Species; Ultraviolet Rays

2010
Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzoates; Benzofurans; Cell Adhesion; Cell Line, Tumor; Cell Nucleus Shape; Cell Proliferation; Cell Survival; Drug Discovery; Drug Screening Assays, Antitumor; Emodin; Humans; Hydroxybenzoates; Lichens; Neoplasms; Osmolar Concentration; S Phase

2011
In situ imaging of usnic acid in selected Cladonia spp. by vibrational spectroscopy.
    The Analyst, 2010, Volume: 135, Issue:12

    Topics: Benzofurans; Lichens; Microscopy; Molecular Structure; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman

2010
Molecular structural studies of lichen substances with antimicrobial, antiproliferative, and cytotoxic effects from Parmelia subrudecta.
    Preparative biochemistry & biotechnology, 2010, Volume: 40, Issue:4

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Benzofurans; Cell Line, Tumor; Cell Proliferation; Humans; Lichens; Magnetic Resonance Spectroscopy; Molecular Structure; Neoplasms; Resorcinols; Salicylates; Spectrometry, Mass, Electrospray Ionization

2010
Collagen-based films containing liposome-loaded usnic acid as dressing for dermal burn healing.
    Journal of biomedicine & biotechnology, 2011, Volume: 2011

    Topics: Actins; Animals; Benzofurans; Biological Dressings; Burns; Collagen; Collagen Type I; Collagen Type III; Immunohistochemistry; Inflammation; Liposomes; Male; Myofibroblasts; Rats; Rats, Wistar; Wound Healing

2011
Production of anti-Helicobacter pylori metabolite by the lichen-forming fungus Nephromopsis pallescens.
    Journal of microbiology (Seoul, Korea), 2011, Volume: 49, Issue:1

    Topics: Anti-Bacterial Agents; Ascomycota; Benzofurans; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Helicobacter pylori; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Temperature

2011
Larvicidal activity of some secondary lichen metabolites against the mosquito Culiseta longiareolata Macquart (Diptera: Culicidae).
    Natural product research, 2012, Volume: 26, Issue:4

    Topics: Animals; Benzoates; Benzofurans; Culicidae; Dibenzoxepins; Hydroxybenzoates; Insecticides; Larva; Lethal Dose 50; Lichens; Molecular Structure

2012
Assessment of usnic acid toxicity in rat primary hepatocytes using ¹³C isotopomer distribution analysis of lactate, glutamate and glucose.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:11

    Topics: Animals; Benzofurans; Carbon; Carbon Isotopes; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hepatocytes; Lactic Acid; Lichens; Mitochondria, Liver; Rats; Rats, Sprague-Dawley

2011
A metabonomic characterization of (+)-usnic acid-induced liver injury by gas chromatography-mass spectrometry-based metabolic profiling of the plasma and liver in rat.
    International journal of toxicology, 2011, Volume: 30, Issue:5

    Topics: Administration, Oral; Animals; Benzofurans; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Hepatocytes; Lipid Metabolism; Liver; Male; Metabolome; Metabolomics; Oxidative Stress; Plasma; Rats; Rats, Wistar; Reproducibility of Results

2011
Mechanical effects, antimicrobial efficacy and cytotoxicity of usnic acid as a biofilm prophylaxis in PMMA.
    Journal of materials science. Materials in medicine, 2011, Volume: 22, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Barium Sulfate; Benzofurans; Biofilms; Bone Cements; Compressive Strength; Fibroblasts; Microscopy, Confocal; Polymethyl Methacrylate; Rabbits; Staphylococcus aureus; Stress, Mechanical; Surface Properties; Zirconium

2011
Effects of usnic acid exposure on human hepatoblastoma HepG2 cells in culture.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:9

    Topics: Anti-Infective Agents; Anti-Obesity Agents; Benzofurans; Biomarkers; Cell Survival; Cytochrome P-450 Enzyme System; Gene Expression; Hep G2 Cells; Hepatoblastoma; Hepatocytes; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Diseases; Oxidative Stress

2012
Effect of usnic acid on Candida orthopsilosis and C. parapsilosis.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Antifungal Agents; Benzofurans; Biofilms; Candida; Candidiasis; Humans; Microbial Sensitivity Tests; Plankton

2012
Evaluation of portable Raman spectrometer with 1064 nm excitation for geological and forensic applications.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 86

    Topics: Amber; Benzoates; Benzofurans; beta Carotene; Calcium Oxalate; Explosive Agents; Forensic Sciences; Fossils; Geology; Illicit Drugs; Mercury Compounds; Minerals; Polystyrenes; Spectrum Analysis, Raman

2012
Intraerythrocytic stages of Plasmodium falciparum biosynthesize vitamin E.
    FEBS letters, 2011, Dec-15, Volume: 585, Issue:24

    Topics: alpha-Tocopherol; Animals; Benzofurans; Erythrocytes; gamma-Tocopherol; Gas Chromatography-Mass Spectrometry; Life Cycle Stages; Lipid Peroxidation; Plasmodium falciparum; Schizonts; Vitamin E

2011
A new depsidone and antibacterial activities of compounds from Usnea undulata Stirton.
    Journal of Asian natural products research, 2011, Volume: 13, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Bacillus cereus; Bacillus subtilis; Benzofurans; Cattle; Depsides; Escherichia coli; Humans; Lactones; Microbial Sensitivity Tests; Salicylates; South Africa; Staphylococcus aureus; Usnea

2011
In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Feb-15, Volume: 19, Issue:3-4

    Topics: Anti-Bacterial Agents; Benzofurans; Clindamycin; Culture Media; Drug Resistance, Multiple, Bacterial; Drug Synergism; Erythromycin; Gentamicins; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Oxacillin

2012
Inhibitory activity of Fe(3) O(4)/oleic acid/usnic acid-core/shell/extra-shell nanofluid on S. aureus biofilm development.
    IEEE transactions on nanobioscience, 2011, Volume: 10, Issue:4

    Topics: Anti-Infective Agents; Benzofurans; Biocompatible Materials; Biofilms; Ferrosoferric Oxide; Microscopy, Confocal; Nanoconjugates; Nanoparticles; Oleic Acid; Oleic Acids; Staphylococcus aureus

2011
Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y).
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2

    Topics: Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Hydrogen Peroxide; Hydroxyl Radical; Nitric Oxide; Oxidation-Reduction; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2012
Cytotoxic activity and antioxidant capacity of purified lichen metabolites: an in vitro study.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:3

    Topics: 4-Butyrolactone; Anisoles; Antioxidants; Apoptosis; Benzofurans; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Depsides; Free Radical Scavengers; Humans; Hydroxybenzoates; Lactones; Lichens; Oxidative Stress; Reactive Oxygen Species; Salicylates

2013
Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.
    Angiogenesis, 2012, Volume: 15, Issue:3

    Topics: Animals; Apoptosis; Benzofurans; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cells, Cultured; Chick Embryo; Female; Humans; Immunohistochemistry; MAP Kinase Signaling System; Mice; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Signal Transduction; Transplantation, Heterologous; Vascular Endothelial Growth Factor Receptor-2

2012
Influence of usnic acid and its derivatives on the activity of mammalian poly(ADP-ribose)polymerase 1 and DNA polymerase β.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2012, Volume: 8, Issue:5

    Topics: Animals; Benzofurans; Cell Line; Cell Survival; DNA; DNA Polymerase beta; Enzyme Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Mice; Molecular Structure; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Recombinant Proteins

2012
Proteomic study on usnic-acid-induced hepatotoxicity in rats.
    Journal of agricultural and food chemistry, 2012, Jul-25, Volume: 60, Issue:29

    Topics: Animals; Benzofurans; Chemical and Drug Induced Liver Injury; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum; Hepatocytes; Liver Diseases; Male; Mitochondria, Liver; Oxidative Stress; Proteins; Proteomics; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transcriptome

2012
Antioxidative and cardiovascular-protective activities of metabolite usnic acid and psoromic acid produced by lichen species Usnea complanata under submerged fermentation.
    Pharmaceutical biology, 2012, Volume: 50, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Benzofurans; Benzoxepins; Biological Products; Bioreactors; Carboxylic Acids; Culture Media, Conditioned; Drug Discovery; Ethnopharmacology; Fermentation; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Kinetics; Lipid Peroxidation; Nitric Oxide; Osmolar Concentration; Solubility; Solvents; Usnea

2012
Interactive toxicity of usnic acid and lipopolysaccharides in human liver HepG2 cells.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:9

    Topics: Anti-Obesity Agents; Benzofurans; Cell Survival; Dietary Supplements; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Gene Expression; Hep G2 Cells; Hepatocytes; Humans; Lipopolysaccharides; Mitochondria, Liver; Mitochondrial Diseases; Oxidative Stress; Transcriptome

2012
Membrane-damaging potential of natural L-(-)-usnic acid in Staphylococcus aureus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012, Volume: 31, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Benzofurans; Cell Membrane; Colony Count, Microbial; Disease Models, Animal; Female; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Microbial Viability; Spleen; Staphylococcal Infections; Usnea

2012
Chemical composition of three Parmelia lichens and antioxidant, antimicrobial and cytotoxic activities of some their major metabolites.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Oct-15, Volume: 19, Issue:13

    Topics: Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Benzofurans; Cell Line, Tumor; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 3-Ring; Humans; Lactones; Lichens; Microbial Sensitivity Tests; Salicylates

2012
Anti-viral activity of (-)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009.
    Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23

    Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Benzofurans; Cell Line; Cell Survival; Dogs; Humans; Influenza A Virus, H1N1 Subtype; Macrophages; Madin Darby Canine Kidney Cells; Mice; Nitric Oxide Synthase Type II; Stereoisomerism; Structure-Activity Relationship; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2012
Biological activities of Toninia candida and Usnea barbata together with their norstictic acid and usnic acid constituents.
    International journal of molecular sciences, 2012, Nov-12, Volume: 13, Issue:11

    Topics: Anti-Infective Agents; Antioxidants; Ascomycota; Bacteria; Benzofurans; Biphenyl Compounds; Cell Cycle; Cell Line, Tumor; Cell Survival; Fungi; Humans; Inhibitory Concentration 50; Lactones; Lichens; Microbial Sensitivity Tests; Molecular Structure; Phenols; Picrates; Salicylates; Usnea

2012
Proton-shuttling lichen compound usnic acid affects mitochondrial and lysosomal function in cancer cells.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Adenosine Triphosphate; Adenylate Kinase; Benzofurans; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Lichens; Lysosomes; Microtubule-Associated Proteins; Mitochondria; Neoplasms; Phagosomes; Protons; Signal Transduction; Vacuoles

2012
Synthesis of a potent antimalarial agent through natural products conjugation.
    ChemMedChem, 2013, Volume: 8, Issue:2

    Topics: Animals; Antimalarials; Artemisinins; Benzofurans; Biological Products; Cell Line; Drug Discovery; Female; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats

2013
Antimicrobial and antibiofilm activity of secondary metabolites of lichens against methicillin-resistant Staphylococcus aureus strains from cystic fibrosis patients.
    Future microbiology, 2013, Volume: 8, Issue:2

    Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Biological Products; Colony Count, Microbial; Cystic Fibrosis; Fumarates; Humans; Hydroxybenzoates; Lichens; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Plant Extracts; Staphylococcal Infections

2013
Lichenic extracts and metabolites as UV filters.
    Journal of photochemistry and photobiology. B, Biology, 2013, Mar-05, Volume: 120

    Topics: Antioxidants; Ascomycota; Benzoates; Benzofurans; Cell Line; Fumarates; Humans; Lactones; Salicylates; Sun Protection Factor; Ultraviolet Rays; Usnea

2013
Harmful effects of usnic acid on hepatic metabolism.
    Chemico-biological interactions, 2013, Apr-25, Volume: 203, Issue:2

    Topics: Adenine Nucleotides; Alanine; Animals; Anti-Obesity Agents; Benzofurans; Fatty Acids; Fructose; Glucose; Glycogen; Glycolysis; Lactic Acid; Liver; Male; Rats; Rats, Wistar

2013
(+)-Usnic acid enamines with remarkable cicatrizing properties.
    Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

    Topics: Animals; Anti-Infective Agents; Antioxidants; Benzofurans; Cell Line; Cell Survival; Humans; Keratinocytes; Lichens; Male; Mice; Rats; Rats, Sprague-Dawley; Wound Healing

2013
Assessment of the genotoxicity and antigenotoxicity of (+)-usnic acid in V79 cells and Swiss mice by the micronucleus and comet assays.
    Mutation research, 2013, May-15, Volume: 753, Issue:2

    Topics: Animals; Antimutagenic Agents; Antioxidants; Benzofurans; Bone Marrow; Cell Line; Comet Assay; Dose-Response Relationship, Drug; Male; Methyl Methanesulfonate; Mice; Micronucleus Tests

2013
Water soluble usnic acid-polyacrylamide complexes with enhanced antimicrobial activity against Staphylococcus epidermidis.
    International journal of molecular sciences, 2013, Apr-02, Volume: 14, Issue:4

    Topics: Acrylic Resins; Anti-Infective Agents; Benzofurans; Solubility; Staphylococcus epidermidis

2013
Seasonal and spatial variation in carbon based secondary compounds in green algal and cyanobacterial members of the epiphytic lichen genus Lobaria.
    Phytochemistry, 2013, Volume: 94

    Topics: Benzofurans; Biomass; Carbon; Chlorophyta; Cyanobacteria; Ecosystem; Lichens; Light; Seasons; Trees

2013
Usnic acid inhibits growth and induces cell cycle arrest and apoptosis in human lung carcinoma A549 cells.
    Nutrition and cancer, 2013, Volume: 65 Suppl 1

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p21; G1 Phase; Gene Expression Regulation; Humans; Lichens; Lung Neoplasms; Poly(ADP-ribose) Polymerases

2013
Inhibition of cytochrome P450s enhances (+)-usnic acid cytotoxicity in primary cultured rat hepatocytes.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:8

    Topics: Animals; Benzoflavones; Benzofurans; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Enzyme Inhibitors; Hepatocytes; Ketoconazole; Liver; Male; Mitochondria; Proadifen; Rats; Rats, Sprague-Dawley; Ticlopidine

2014
Anionic polymers and 10 nm Fe₃O₄@UA wound dressings support human foetal stem cells normal development and exhibit great antimicrobial properties.
    International journal of pharmaceutics, 2014, Mar-25, Volume: 463, Issue:2

    Topics: Alginates; Anti-Infective Agents; Bandages; Benzofurans; Biofilms; Carboxymethylcellulose Sodium; Cell Line; Cells, Cultured; Fetal Stem Cells; Glucuronic Acid; Hexuronic Acids; Humans; Magnetite Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; X-Ray Diffraction

2014
(+)-Usnic acid-induced myocardial toxicity in rats.
    Toxicologic pathology, 2015, Volume: 43, Issue:3

    Topics: Amino Acids; Animals; Anti-Infective Agents; Benzofurans; Endoplasmic Reticulum Stress; Female; Gene Expression; Heart Diseases; Microarray Analysis; Myocardium; Oxidative Stress; Rats; Rats, Inbred F344; RNA

2015
In vitro risk assessment of usnic acid.
    Toxicology and industrial health, 2016, Volume: 32, Issue:3

    Topics: Adult; Benzofurans; Cells, Cultured; Chromosome Aberrations; DNA Damage; Humans; Lichens; Lymphocytes; Micronucleus Tests; Oxidative Stress; Turkey; Young Adult

2016
Lichen secondary metabolites as DNA-interacting agents.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:2

    Topics: Animals; Benzoates; Benzofurans; Cattle; Circular Dichroism; DNA; Emodin; Humans; Hydroxybenzoates; Intercalating Agents; Kinetics; Lichens; Nucleic Acid Conformation; Spectrophotometry, Ultraviolet; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2014
Dietary supplementation of usnic acid, an antimicrobial compound in lichens, does not affect rumen bacterial diversity or density in reindeer.
    Current microbiology, 2014, Volume: 68, Issue:6

    Topics: Animals; Anti-Infective Agents; Archaea; Bacteria; Benzofurans; Biota; Denaturing Gradient Gel Electrophoresis; Dietary Supplements; Molecular Sequence Data; Reindeer; Rumen; Sequence Analysis, DNA

2014
Antibacterial activity of lichen secondary metabolite usnic acid is primarily caused by inhibition of RNA and DNA synthesis.
    FEMS microbiology letters, 2014, Volume: 353, Issue:1

    Topics: Anti-Bacterial Agents; Benzofurans; DNA; Gram-Positive Bacteria; Lichens; Microbial Sensitivity Tests; RNA

2014
The synthesis, characterization, antimicrobial and antimutagenic activities of hydroxyphenylimino ligands and their metal complexes of usnic acid isolated from Usnea longissima.
    Dalton transactions (Cambridge, England : 2003), 2014, Apr-28, Volume: 43, Issue:16

    Topics: Aminophenols; Anti-Infective Agents; Antimutagenic Agents; Bacteria; Benzofurans; Coordination Complexes; Ligands; Metals, Heavy; Mutagens; Usnea; Yeasts

2014
[Study on the chemical constituents of two lichen plants from Meng Mountain].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:9

    Topics: Benzofurans; China; Chromatography, High Pressure Liquid; Hydroxybenzoates; Lactones; Lichens; Molecular Structure; Resorcinols; Salicylates; Solvents

2013
Anionic form of usnic acid promotes lamellar to nonlamellar transition in DPPC and DOPC membranes.
    The journal of physical chemistry. B, 2014, Apr-10, Volume: 118, Issue:14

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Anions; Benzofurans; Hydrogen Bonding; Liposomes; Molecular Dynamics Simulation; Phosphatidylcholines

2014
Usnic acid and triacylglycerides production by the cultured lichen mycobiont of Ramalina celastri.
    Natural product communications, 2014, Volume: 9, Issue:2

    Topics: Benzofurans; Lichens; Symbiosis; Triglycerides

2014
Usnic acid-loaded biocompatible magnetic PLGA-PVA microsphere thin films fabricated by MAPLE with increased resistance to staphylococcal colonization.
    Biofabrication, 2014, Volume: 6, Issue:3

    Topics: Benzofurans; Biocompatible Materials; Biofilms; Drug Carriers; Drug Delivery Systems; Drug Resistance, Bacterial; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus

2014
Cytotoxic constituents from Lobaria scrobiculata and a comparison of two bioassays for their evaluation.
    Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4

    Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Benzofurans; Drug Screening Assays, Antitumor; France; HL-60 Cells; Humans; Lichens; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Trypan Blue

2014
Acaricidal activity of usnic acid and sodium usnic acid against Psoroptes cuniculi in vitro.
    Parasitology research, 2014, Volume: 113, Issue:6

    Topics: Acaricides; Animals; Benzofurans; Dose-Response Relationship, Drug; Heterocyclic Compounds, 3-Ring; Molecular Structure; Psoroptidae

2014
Clastogenic effect of atranorin, evernic acid, and usnic acid on human lymphocytes.
    Natural product communications, 2014, Volume: 9, Issue:4

    Topics: Benzofurans; Cell Proliferation; Humans; Hydroxybenzoates; Lymphocytes; Molecular Structure

2014
Release behavior and antibiofilm activity of usnic acid-loaded carboxylated poly(L-lactide) microparticles.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:2

    Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Calorimetry, Differential Scanning; Carboxylic Acids; Microscopy, Electron, Scanning; Polyesters; Staphylococcus epidermidis

2014
Uncommon chlorinated xanthone and other antibacterial compounds from the lichen Cladonia incrassata.
    Planta medica, 2014, Volume: 80, Issue:11

    Topics: Anti-Bacterial Agents; Aspergillus; Benzofurans; Candida albicans; Halogenation; Lichens; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Xanthenes; Xanthones

2014
Usnic acid protects LPS-induced acute lung injury in mice through attenuating inflammatory responses and oxidative stress.
    International immunopharmacology, 2014, Volume: 22, Issue:2

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Benzofurans; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Glutathione; Hydrogen Peroxide; Lipopolysaccharides; Lung; Male; Mice; Oxidative Stress; Peroxidase; Superoxide Dismutase

2014
The role of autophagy in usnic acid-induced toxicity in hepatic cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 142, Issue:1

    Topics: Apoptosis; Autophagy; Benzofurans; Caspase 3; Caspase 7; Cell Culture Techniques; Cell Cycle; Cell Survival; Hep G2 Cells; Humans; Liver; MAP Kinase Kinase 4; MAP Kinase Signaling System

2014
Anticancer activities of selected species of North American lichen extracts.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:1

    Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Lactones; Lichens; Lymphocytes; Molecular Structure; Salicylates; Thymidine Kinase; Tumor Suppressor Protein p53; United States

2015
Usnic acid inhibits ER stress activation through AMPK signaling pathway in rat cardiomyocytes.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:17

    Topics: AMP-Activated Protein Kinases; Animals; Benzofurans; Cells, Cultured; Endoplasmic Reticulum Stress; Enzyme Activation; Gene Expression; Myocytes, Cardiac; Phosphorylation; Rats; Signal Transduction

2014
Lichen secondary metabolites in Flavocetraria cucullata exhibit anti-cancer effects on human cancer cells through the induction of apoptosis and suppression of tumorigenic potentials.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzofurans; Carcinogenesis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; G1 Phase; Humans; Lichens; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins c-akt; Secondary Metabolism

2014
Usnic acid, a lichen secondary metabolite inhibits Group A Streptococcus biofilms.
    Antonie van Leeuwenhoek, 2015, Volume: 107, Issue:1

    Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Biomass; Cytosol; Fatty Acids; Humans; Lichens; Microscopy, Confocal; Pharyngitis; Secondary Metabolism; Spectroscopy, Fourier Transform Infrared; Streptococcal Infections; Streptococcus pyogenes

2015
Usnic acid potassium salt: an alternative for the control of Biomphalaria glabrata (Say, 1818).
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Animals; Benzofurans; Biomphalaria; Molluscacides; Schistosoma mansoni; Schistosomiasis

2014
Novel derivatives of usnic acid effectively inhibiting reproduction of influenza A virus.
    Bioorganic & medicinal chemistry, 2014, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Antiviral Agents; Benzofurans; Cell Survival; Dogs; Humans; Influenza A virus; Madin Darby Canine Kidney Cells; Stereoisomerism; Structure-Activity Relationship; Virus Replication

2014
Usnic acid and its versatility as MALDI matrix.
    Journal of mass spectrometry : JMS, 2015, Volume: 50, Issue:1

    Topics: Benzofurans; Cytochromes c; Depsides; Gramicidin; Insulin, Regular, Pork; Lichens; Myoglobin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Yohimbine

2015
Absence of psoralen--type phototoxicity from usnic acid, some lichens, and lichen substances.
    The Journal of investigative dermatology, 1966, Volume: 47, Issue:1

    Topics: Benzofurans; Dermatitis, Phototoxic; Lichens

1966
In vitro antimicrobial activity of extracts and compounds isolated from Cladonia uncialis.
    Natural product research, 2015, Volume: 29, Issue:24

    Topics: Anti-Infective Agents; Ascomycota; Benzofurans; Candida albicans; Escherichia coli; Lichens; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus aureus

2015
Ultrastructural analysis of Leishmania infantum chagasi promastigotes forms treated in vitro with usnic acid.
    TheScientificWorldJournal, 2015, Volume: 2015

    Topics: Animals; Benzofurans; In Vitro Techniques; Leishmania infantum

2015
Endoplasmic Reticulum Stress and Store-Operated Calcium Entry Contribute to Usnic Acid-Induced Toxicity in Hepatic Cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 146, Issue:1

    Topics: Benzofurans; Calcium; Endoplasmic Reticulum; Hep G2 Cells; Humans; Stress, Physiological

2015
Design and characterization of antimicrobial usnic acid loaded-core/shell magnetic nanoparticles.
    Materials science & engineering. C, Materials for biological applications, 2015, Volume: 52

    Topics: Anti-Infective Agents; Benzofurans; Magnetics; Magnetite Nanoparticles; Staphylococcus epidermidis

2015
Development of Fe-based bulk metallic glasses as potential biomaterials.
    Materials science & engineering. C, Materials for biological applications, 2015, Volume: 52

    Topics: Benzofurans; Biocompatible Materials; Materials Testing; Microscopy, Electron, Transmission; Nanocomposites; Staphylococcus epidermidis

2015
Anti-angiogenic and antiproliferative properties of the lichen substances (-)-usnic acid and vulpinic acid.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2015, Volume: 70, Issue:5-6

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Benzofurans; Cell Line, Tumor; Furans; Human Umbilical Vein Endothelial Cells; Humans; Lichens; Phenylacetates

2015
An in vitro study on the antioxidant capacity of usnic acid on human erythrocytes and molecular models of its membrane.
    Biochimica et biophysica acta, 2015, Volume: 1848, Issue:11 Pt A

    Topics: Antioxidants; Benzofurans; Cell Shape; Cells, Cultured; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Hypochlorous Acid; Lipid Bilayers; Microscopy; Microscopy, Electron, Scanning; Models, Molecular; Molecular Structure; Phosphatidylethanolamines; X-Ray Diffraction

2015
Evaluation of baicalein, chitosan and usnic acid effect on Candida parapsilosis and Candida krusei biofilm using a Cellavista device.
    Journal of microbiological methods, 2015, Volume: 118

    Topics: Amphotericin B; Anti-Infective Agents; Benzofurans; Biofilms; Candida; Chitosan; Flavanones; Humans; Image Processing, Computer-Assisted; Microbial Sensitivity Tests; Microscopy

2015
Usnic acid inhibits biofilm formation and virulent morphological traits of Candida albicans.
    Microbiological research, 2015, Volume: 179

    Topics: Antifungal Agents; Benzofurans; Biofilms; Candida albicans; Hyphae; Lichens; Microscopy, Confocal; Spectroscopy, Fourier Transform Infrared; Virulence

2015
Optimisation and establishment of separation conditions of organic acids from Usnea longissima Ach. by pH-zone-refining counter-current chromatography: Discussion of the eluotropic sequence.
    Journal of chromatography. A, 2016, Jan-04, Volume: 1427

    Topics: Anisoles; Benzofurans; Chromatography, High Pressure Liquid; Countercurrent Distribution; Hydrogen-Ion Concentration; Hydroxybenzoates; Phthalic Acids; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Usnea

2016
Evaluation of Anticancer and Antioxidant Activity of a Commercially Available CO2 Supercritical Extract of Old Man's Beard (Usnea barbata).
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Autophagy; Benzofurans; Biphenyl Compounds; Carbon Dioxide; Cell Cycle; Cell Line, Tumor; Chromatography, Supercritical Fluid; Mice; Oxidation-Reduction; Picrates; Rats; Usnea

2016
Inhibitory Activity of (+)-Usnic Acid against Non-Small Cell Lung Cancer Cell Motility.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Benzofurans; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Inhibitory Concentration 50; Lichens; Lung Neoplasms; Mass Spectrometry; Neoplasm Invasiveness; Neoplasm Metastasis; Real-Time Polymerase Chain Reaction; Romania

2016
Biocompatible 3D Matrix with Antimicrobial Properties.
    Molecules (Basel, Switzerland), 2016, Jan-20, Volume: 21, Issue:1

    Topics: Anti-Infective Agents; Benzofurans; Biocompatible Materials; Cell Line; Cell Survival; Collagen; Durapatite; Humans; Materials Testing; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Spectroscopy, Fourier Transform Infrared; Tissue Engineering; Tissue Scaffolds; X-Ray Diffraction

2016
Putative identification of the usnic acid biosynthetic gene cluster by de novo whole-genome sequencing of a lichen-forming fungus.
    Fungal biology, 2016, Volume: 120, Issue:3

    Topics: Ascomycota; Benzofurans; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Gene Expression Profiling; Genome, Fungal; Ligases; Multigene Family; Oxidoreductases; Phylogeny; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2016
Effects of (+)-usnic acid and (+)-usnic acid-liposome on Toxoplasma gondii.
    Experimental parasitology, 2016, Volume: 166

    Topics: Animals; Antiprotozoal Agents; Benzofurans; Cells, Cultured; Female; Fibroblasts; Liposomes; Male; Mice; Microscopy, Electron, Transmission; Myocytes, Cardiac; Random Allocation; Rats; Rats, Sprague-Dawley; Toxoplasma; Toxoplasmosis, Animal; Usnea

2016
Derivatives of usnic acid inhibit broad range of influenza viruses and protect mice from lethal influenza infection.
    Antiviral chemistry & chemotherapy, 2015, Volume: 24, Issue:3-4

    Topics: Animals; Antiviral Agents; Benzofurans; Cell Survival; Dogs; Dose-Response Relationship, Drug; Female; Hepatocytes; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Orthomyxoviridae; Orthomyxoviridae Infections; Structure-Activity Relationship

2015
Chemical diversity and antiviral potential in the pantropical Diospyros genus.
    Fitoterapia, 2016, Volume: 112

    Topics: Animals; Antiviral Agents; Benzofurans; Chlorocebus aethiops; COS Cells; Dengue Virus; Diospyros; Metabolome; Plant Bark; Plant Extracts; Triterpenes; Virus Replication

2016
Effects of the encapsulation of usnic acid into liposomes and interactions with antituberculous agents against multidrug-resistant tuberculosis clinical isolates.
    Memorias do Instituto Oswaldo Cruz, 2016, Volume: 111, Issue:5

    Topics: Antibiotics, Antitubercular; Benzofurans; Capsules; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Isoniazid; Liposomes; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin

2016
Bactericidal Activity of Usnic Acid-Loaded Electrospun Fibers.
    Recent patents on nanotechnology, 2016, Volume: 10, Issue:3

    Topics: Anti-Bacterial Agents; Benzofurans; Patents as Topic; Polymethacrylic Acids; Staphylococcus aureus

2016
Usnic Acid Derivatives with Cytotoxic and Antifungal Activities from the Lichen Usnea longissima.
    Journal of natural products, 2016, 05-27, Volume: 79, Issue:5

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Apoptosis; Benzofurans; Candida; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Methotrexate; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Trichophyton; Usnea

2016
Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells.
    Archives of toxicology, 2017, Volume: 91, Issue:3

    Topics: Antioxidant Response Elements; Benzofurans; DNA Damage; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Hep G2 Cells; Humans; NF-E2-Related Factor 2; Reactive Oxygen Species; S Phase Cell Cycle Checkpoints; Signal Transduction

2017
Activity of the Lichen Usnea steineri and its Major Metabolites against Gram-positive, Multidrug-resistant Bacteria.
    Natural product communications, 2016, Volume: 11, Issue:4

    Topics: Anti-Bacterial Agents; Benzofurans; Depsides; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Usnea

2016
Usnic Acid and Its Evolving Role as a Potent Antineoplastic Agent.
    Toxicologic pathology, 2016, Volume: 44, Issue:6

    Topics: Antineoplastic Agents; Benzofurans; Humans

2016
Evaluation of mutagenic, recombinogenic and carcinogenic potential of (+)-usnic acid in somatic cells of Drosophila melanogaster.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 96

    Topics: Animals; Anti-Infective Agents; Benzofurans; Carcinogenesis; Carcinogens; Drosophila melanogaster; Larva; Mutagenesis; Mutagens; Recombination, Genetic; Wings, Animal

2016
Evaluation of antibacterial and antibiofilm mechanisms by usnic acid against methicillin-resistant Staphylococcus aureus.
    Future microbiology, 2016, Volume: 11

    Topics: Adhesins, Bacterial; Anti-Bacterial Agents; Bacterial Proteins; Benzofurans; Biofilms; Carrier Proteins; Cell Membrane; Cell Survival; Colony Count, Microbial; Cystic Fibrosis; DNA, Bacterial; Down-Regulation; Lipase; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Peptidoglycan; Propidium; Protein Interaction Maps; Proteomics; Real-Time Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staphylococcal Infections; Time Factors; Virulence

2016
Lichen secondary metabolites affect growth of Physcomitrella patens by allelopathy.
    Protoplasma, 2017, Volume: 254, Issue:3

    Topics: Allelopathy; Benzofurans; Bryopsida; Cell Division; Cell Size; Germ Cells, Plant; Heterocyclic Compounds, 3-Ring; Hydroxybenzoates; Lichens; Plant Extracts; Salicylates; Secondary Metabolism

2017
Lichen-derived compounds show potential for central nervous system therapeutics.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Nov-15, Volume: 23, Issue:12

    Topics: Acetylcholinesterase; Animals; Benzoates; Benzofurans; Biological Products; Brain-Derived Neurotrophic Factor; Cell Line; Central Nervous System; Central Nervous System Diseases; Cholinesterase Inhibitors; Depsides; Dibenzoxepins; Gene Expression; Hydroxybenzoates; Lactones; Lichens; Mice; Nerve Growth Factor; Neural Stem Cells; Neurogenesis

2016
Tyrosyl-DNA Phosphodiesterase 1 Inhibitors: Usnic Acid Enamines Enhance the Cytotoxic Effect of Camptothecin.
    Journal of natural products, 2016, 11-23, Volume: 79, Issue:11

    Topics: Benzofurans; Camptothecin; DNA Topoisomerases, Type I; Humans; MCF-7 Cells; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases

2016
Antiangiogenic and Toxic Effects of Genistein, Usnic Acid, and Their Copper Complexes in Zebrafish Embryos at Different Developmental Stages.
    Chemistry & biodiversity, 2017, Volume: 14, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Axitinib; Benzofurans; Cell Line, Tumor; Cell Movement; Cell Survival; Coordination Complexes; Copper; Embryo, Nonmammalian; Embryonic Development; Genistein; Humans; Imidazoles; Indazoles; Matrix Metalloproteinases; Microscopy, Fluorescence; Neovascularization, Physiologic; Zebrafish

2017
A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut.
    ACS chemical biology, 2016, 12-16, Volume: 11, Issue:12

    Topics: Animals; Anopheles; Antimalarials; Benzofurans; Cell Line; Drug Discovery; Female; Insect Vectors; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Zygote

2016
Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, 03-01, Volume: 156, Issue:1

    Topics: Acetylation; Administration, Oral; Animals; Benzofurans; Carcinogens; Chromatin Assembly and Disassembly; Dose-Response Relationship, Drug; Epigenesis, Genetic; Hepatocyte Nuclear Factor 1-alpha; Histones; Homeodomain Proteins; Kidney; Liver; Lysine; Male; Methapyrilene; Methylation; Organ Specificity; PPAR alpha; Protein Processing, Post-Translational; Random Allocation; Rats, Inbred F344; Tumor Suppressor Proteins

2017
Constituents of Ramalina capitata (Ach.) Nyl. extracts.
    Natural product research, 2017, Volume: 31, Issue:7

    Topics: Ascomycota; Benzofurans; Chromatography, Gas; Flame Ionization; Gas Chromatography-Mass Spectrometry; Methanol; Resorcinols; Solvents

2017
Usnic acid and atranorin exert selective cytostatic and anti-invasive effects on human prostate and melanoma cancer cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40

    Topics: Actins; Antineoplastic Agents; Apoptosis; Benzofurans; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cytostatic Agents; Fibroblasts; Humans; Hydroxybenzoates; Male; Melanoma; Prostatic Neoplasms

2017
Synthesis and anti-inflammatory activity of novel triazole hybrids of (+)-usnic acid, the major dibenzofuran metabolite of the lichen Usnea longissima.
    Molecular diversity, 2017, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents; Benzofurans; Click Chemistry; Humans; Interleukin-1beta; Triazoles; Tumor Necrosis Factor-alpha; U937 Cells; Usnea

2017
Usnic Acid Benzylidene Analogues as Potent Mechanistic Target of Rapamycin Inhibitors for the Control of Breast Malignancies.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: Animals; Apoptosis; Autophagy; Benzofurans; Benzylidene Compounds; Breast Neoplasms; Cell Proliferation; Crystallography, X-Ray; Disease Models, Animal; Female; Humans; Lichens; Mice; Mice, Nude; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Kinase Inhibitors; Sirolimus; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2017
Effect-enhancing and toxicity-reducing activity of usnic acid in ascitic tumor-bearing mice treated with bleomycin.
    International immunopharmacology, 2017, Volume: 46

    Topics: Adjuvants, Pharmaceutic; Animals; Antineoplastic Agents; Apoptosis; Ascites; Benzofurans; Bleomycin; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Drug-Related Side Effects and Adverse Reactions; Humans; Lichens; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pulmonary Fibrosis; Smad Proteins

2017
Morphological, Secondary Metabolite and ITS (rDNA) Variability within Usnic Acid-Containing Lichen Thalli of Xanthoparmelia Explored at the Local Scale of Rock Outcrop in W-Alps.
    Chemistry & biodiversity, 2017, Volume: 14, Issue:6

    Topics: Benzofurans; Chromatography, High Pressure Liquid; DNA, Ribosomal; Europe; Haplotypes; Italy; Lichens; Parmeliaceae; Secondary Metabolism; Tandem Mass Spectrometry

2017
Teratogenic Effect of Usnic Acid from
    BioMed research international, 2017, Volume: 2017

    Topics: Animals; Ascomycota; Benzofurans; Body Weight; Female; Fetal Development; Fetus; Male; Organ Size; Organogenesis; Pregnancy; Rats; Teratogenesis

2017
Protective effects of lichen metabolites evernic and usnic acids against redox impairment-mediated cytotoxicity in central nervous system-like cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 105

    Topics: Antioxidants; Apoptosis; Benzofurans; Caspase 3; Cell Line, Tumor; Central Nervous System; Humans; Hydrogen Peroxide; Hydroxybenzoates; Lichens; Oxidation-Reduction; Oxidative Stress; Protective Agents

2017
Comprehensive Evaluation of (+)-Usnic Acid-induced Cardiotoxicity in Rats by Sequential Cross-omics Analysis.
    Toxicologic pathology, 2017, Volume: 45, Issue:4

    Topics: Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Benzofurans; Bile Acids and Salts; Cardiotoxicity; Creatine Kinase; Endoplasmic Reticulum Stress; Female; Heart; L-Lactate Dehydrogenase; Liver; Metabolomics; Methylenetetrahydrofolate Dehydrogenase (NADP); Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Inbred F344; Up-Regulation

2017
Specialized Metabolites of the Lichen Vulpicida pinastri Act as Photoprotective Agents.
    Molecules (Basel, Switzerland), 2017, Jul-12, Volume: 22, Issue:7

    Topics: Antioxidants; Benzofurans; Furans; Humans; Keratinocytes; Lichens; Phenylacetates; Plant Extracts; Radiation-Protective Agents; Ultraviolet Rays

2017
The Preparation of Hyaluronic Acid Nanoparticles from Aspicilia lichens Using Bifido Bacteria for Help in the Treatment of Diabetes in Rats In Vivo.
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:10

    Topics: Animals; Ascomycota; Benzofurans; Bifidobacterium; Biological Products; Blood Glucose; Diabetes Mellitus, Experimental; Fruit; Humans; Hyaluronic Acid; Nanoparticles; Rats; Sheep; Spectroscopy, Fourier Transform Infrared

2017
Effects of fluorine-containing usnic acid and fungus Beauveria bassiana on the survival and immune-physiological reactions of Colorado potato beetle larvae.
    Pest management science, 2018, Volume: 74, Issue:3

    Topics: Animal Shells; Animals; Beauveria; Benzofurans; Coleoptera; Fluorine; Hemolymph; Immunity, Innate; Insect Control; Insecticides; Larva; Longevity; Pest Control, Biological

2018
Plasmodium falciparum uses vitamin E to avoid oxidative stress.
    Parasites & vectors, 2017, Oct-10, Volume: 10, Issue:1

    Topics: Animals; Antimalarials; Benzofurans; Chloroquine; Erythrocytes; Humans; Malaria, Falciparum; Microscopy, Fluorescence; Oxidative Stress; Perylene; Plasmodium falciparum; Protozoan Proteins; Reactive Oxygen Species; Vitamin E

2017
Simultaneous determination of usnic, diffractaic, evernic and barbatic acids in rat plasma by ultra-high-performance liquid chromatography-quadrupole exactive Orbitrap mass spectrometry and its application to pharmacokinetic studies.
    Biomedical chromatography : BMC, 2018, Volume: 32, Issue:3

    Topics: Animals; Anisoles; Benzofurans; Chromatography, High Pressure Liquid; Female; Hydroxybenzoates; Linear Models; Male; Mass Spectrometry; Phthalic Acids; Rats; Reproducibility of Results; Sensitivity and Specificity

2018
The effects of sodium usnic acid by topical application on skin wound healing in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Benzofurans; Male; Rats; Rats, Wistar; Skin; Sodium; Treatment Outcome; Wound Healing

2018
Preparation and evaluation of wet-milled usnic acid nanocrystal suspension for better bioaffinity.
    Drug development and industrial pharmacy, 2018, Volume: 44, Issue:5

    Topics: Animals; Benzofurans; Biological Availability; Caco-2 Cells; Humans; Mass Spectrometry; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Rats; Solubility; Suspensions

2018
Toxicity of Usnic Acid from Cladonia substellata (Lichen) to embryos and adults of Biomphalaria glabrata.
    Acta tropica, 2018, Volume: 179

    Topics: Animals; Artemia; Benzofurans; Biomphalaria; Embryo, Nonmammalian; Larva; Lichens; Molluscacides

2018
Pro/Antigenotoxic Activity of Usnic Acid Enantiomers In Vitro.
    Bulletin of experimental biology and medicine, 2018, Volume: 164, Issue:3

    Topics: Benzofurans; Comet Assay; DNA Fragmentation; Hormesis; Humans; Leukocytes, Mononuclear; Lichens; Methyl Methanesulfonate; Mutagens; Protective Agents; Quinoxalines; Stereoisomerism

2018
Usnic Acid Induces Cycle Arrest, Apoptosis, and Autophagy in Gastric Cancer Cells In Vitro and In Vivo.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Jan-28, Volume: 24

    Topics: Animals; Apoptosis; Autophagy; Benzofurans; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Shape; Female; Mice; Mice, Inbred BALB C; Mice, Nude; Stomach Neoplasms

2018
Research for the lichen Usnea barbata metabolites.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2018, Jul-26, Volume: 73, Issue:7-8

    Topics: Anti-Bacterial Agents; Antioxidants; Bacillus subtilis; Benzofurans; Biological Factors; Microbial Sensitivity Tests; Phenols; Pseudomonas fluorescens; Solvents; Usnea

2018
Usnic acid-loaded polyaniline/polyurethane foam wound dressing: preparation and bactericidal activity.
    Materials science & engineering. C, Materials for biological applications, 2018, Aug-01, Volume: 89

    Topics: Aniline Compounds; Anti-Bacterial Agents; Bandages; Benzofurans; Biofilms; Disk Diffusion Antimicrobial Tests; Drug Carriers; Escherichia coli; Microscopy, Electron, Scanning; Polyurethanes; Staphylococcus aureus

2018
Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus.
    Planta medica, 2018, Volume: 84, Issue:17

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Benzofurans; Drug Interactions; Ethidium; Microbial Sensitivity Tests; Mycobacterium abscessus

2018
Usnic acid reactive metabolites formation in human, rat, and mice microsomes. Implication for hepatotoxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 120

    Topics: Animals; Benzofurans; Biotransformation; Chromatography, Liquid; Glutathione; Humans; Liver; Mice; Microsomes, Liver; Rats; Stereoisomerism; Tandem Mass Spectrometry

2018
Identification of a putative polyketide synthase gene involved in usnic acid biosynthesis in the lichen Nephromopsis pallescens.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Amino Acid Sequence; Base Sequence; Benzofurans; Lichens; Parmeliaceae; Phylogeny; Polyketide Synthases; Sequence Analysis, DNA

2018
Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors.
    Bioorganic & medicinal chemistry, 2018, 08-15, Volume: 26, Issue:15

    Topics: Allosteric Regulation; Antineoplastic Agents; Benzofurans; Binding Sites; Cell Survival; DNA; Furans; HEK293 Cells; Humans; Molecular Docking Simulation; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity

2018
The role of usnic acid-induced apoptosis and autophagy in hepatocellular carcinoma.
    Human & experimental toxicology, 2019, Volume: 38, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Benzofurans; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Humans; Liver Neoplasms

2019
In vitro cytotoxic and antiproliferative effects of usnic acid on hormone-dependent breast and prostate cancer cells.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Female; G1 Phase; Humans; Inhibitory Concentration 50; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Resting Phase, Cell Cycle

2018
Inhibitory Effect of New Semisynthetic Usnic Acid Derivatives on Human Tyrosyl-DNA Phosphodiesterase 1.
    Planta medica, 2019, Volume: 85, Issue:2

    Topics: Benzofurans; Cell Line, Tumor; Escherichia coli; HEK293 Cells; Humans; MCF-7 Cells; Microorganisms, Genetically-Modified; Molecular Docking Simulation; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases

2019
Two new usnic acid derivatives from the endophytic fungus Mycosphaerella sp.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2018, Nov-27, Volume: 73, Issue:11-12

    Topics: Antifungal Agents; Ascomycota; Benzofurans; Cryptococcus; Eugenia

2018
Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Benzofurans; Cell Line; Cicatrix; Disease Models, Animal; Female; Human Umbilical Vein Endothelial Cells; Humans; Male; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Rabbits

2018
Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer.
    Scientific reports, 2018, 11-02, Volume: 8, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzofurans; Biological Availability; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Neoplasm Invasiveness; Potassium; Selenic Acid; Treatment Outcome

2018
Synthesis and antimycobacterial activity of (+)-usnic acid conjugates.
    Archiv der Pharmazie, 2018, Volume: 351, Issue:12

    Topics: Anti-Bacterial Agents; Benzofurans; Cell Line; Cell Survival; Drug Design; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Mycobacterium tuberculosis

2018
Determination of Usnic Acid Responsive miRNAs in Breast Cancer Cell Lines.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:12

    Topics: Antineoplastic Agents; Benzofurans; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; MicroRNAs; Molecular Docking Simulation; Molecular Structure; Oligonucleotide Array Sequence Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

2019
Usnic acid potassium salt from Cladonia substellata (Lichen): Synthesis, cytotoxicity and in vitro anthelmintic activity and ultrastructural analysis against adult worms of Schistosoma mansoni.
    Acta tropica, 2019, Volume: 192

    Topics: Animals; Anthelmintics; Benzofurans; Cell Survival; Dose-Response Relationship, Drug; Female; Leukocytes, Mononuclear; Lichens; Male; Microscopy, Electron, Scanning; Schistosoma mansoni

2019
Heparin appended ADH-anionic polysaccharide nanoparticles for site-specific delivery of usnic acid.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: A549 Cells; Adipates; Animals; Antineoplastic Agents; Apoptosis; Benzofurans; Cell Cycle; Drug Carriers; Drug Liberation; Erythrocytes; Hematologic Tests; Hemolysis; Heparin; Humans; Male; Nanoparticles; Polysaccharides, Bacterial; Rats

2019
Metabolites identification of (+)-usnic acid in vivo by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
    Fitoterapia, 2019, Volume: 133

    Topics: Animals; Benzofurans; Bile; Chromatography, High Pressure Liquid; Male; Molecular Structure; Plasma; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Urine

2019
Antibacterial activity of the lichens
    Natural product research, 2020, Volume: 34, Issue:23

    Topics: Acetone; Anti-Bacterial Agents; Anti-Infective Agents; Aspergillus; Benzofurans; Candida albicans; Heterocyclic Compounds, 3-Ring; Lichens; Microbial Sensitivity Tests; Molecular Structure; Parmeliaceae; Secondary Metabolism; Staphylococcus aureus

2020
Biosynthesis of Ag and Cu NPs by secondary metabolites of usnic acid and thymol with biological macromolecules aggregation and antibacterial activities against multi drug resistant (MDR) bacteria.
    International journal of biological macromolecules, 2019, May-01, Volume: 128

    Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Chemistry Techniques, Synthetic; Copper; Drug Resistance, Multiple, Bacterial; Metal Nanoparticles; Microbial Sensitivity Tests; Silver; Thymol

2019
Mechanism of action of an old antibiotic revisited: Role of calcium ions in protonophoric activity of usnic acid.
    Biochimica et biophysica acta. Bioenergetics, 2019, 04-01, Volume: 1860, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Bacillus subtilis; Benzofurans; Calcimycin; Calcium; Ion Transport; Lipid Bilayers; Membrane Potential, Mitochondrial; Mitochondria, Liver; Rats

2019
Genotoxicity of (+)- and (-)-usnic acid in mice.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2019, Volume: 839

    Topics: Animals; Anti-Infective Agents; Benzofurans; DNA Damage; Kidney; Lichens; Liver; Male; Mice; Oxidative Stress; Stereoisomerism

2019
Structural Elucidation and Free Radical Scavenging Activity of a new o-Orsellinic Acid Derivative Isolated from the Lichen Cladonia rappii.
    Natural product communications, 2016, Volume: 11, Issue:9

    Topics: Benzofurans; Brazil; Free Radical Scavengers; Lichens; Molecular Structure; Resorcinols; Resveratrol

2016
Inhibitory Effects of Usnic and Carnosic Acid on Some Metabolic Enzymes: An In vitro Study.
    Protein and peptide letters, 2019, Volume: 26, Issue:5

    Topics: Abietanes; Antioxidants; Aryldialkylphosphatase; Benzofurans; Enzyme Inhibitors; Glutathione Reductase; Glutathione Transferase; Humans; Oxidation-Reduction; Rosmarinus

2019
Bioadhesive polymeric films based on usnic acid for burn wound treatment: Antibacterial and cytotoxicity studies.
    Colloids and surfaces. B, Biointerfaces, 2019, Jun-01, Volume: 178

    Topics: Animals; Anti-Bacterial Agents; Bacillus cereus; Benzofurans; Burns; Cell Survival; Enterococcus faecalis; Humans; Keratinocytes; Polymers; Staphylococcus epidermidis; Streptococcus pyogenes; Swine; Wound Healing

2019
Synergistic effects of hormone therapy drugs and usnic acid on hormone receptor-positive breast and prostate cancer cells.
    Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzofurans; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Humans; Male; Prostatic Neoplasms; Receptors, Cell Surface

2019
Tocopherol biosynthesis in
    FEBS open bio, 2019, Volume: 9, Issue:4

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Benzofurans; Cyclohexanones; Enzyme Inhibitors; Leishmania; Nitrobenzoates; Tocopherols

2019
Investigation of new treatment option for hepatocellular carcinoma: a combination of sorafenib with usnic acid.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:7

    Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Benzofurans; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; Hep G2 Cells; Humans; Liver Neoplasms; Protein-Tyrosine Kinases; Sorafenib

2019
Usnic acid modifies MRSA drug resistance through down-regulation of proteins involved in peptidoglycan and fatty acid biosynthesis.
    FEBS open bio, 2019, Volume: 9, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Benzofurans; Drug Resistance; Drug Synergism; Fatty Acids; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Norfloxacin; Peptidoglycan; Staphylococcal Infections; Staphylococcus aureus

2019
Usnic acid attenuates genomic instability in Chinese hamster ovary (CHO) cells as well as chemical-induced preneoplastic lesions in rat colon.
    Journal of toxicology and environmental health. Part A, 2019, Volume: 82, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Benzofurans; CHO Cells; Colonic Neoplasms; Cricetinae; Cricetulus; Genomic Instability; Mutagenicity Tests; Precancerous Conditions

2019
Overcoming deterrent metabolites by gaining essential nutrients: A lichen/snail case study.
    Phytochemistry, 2019, Volume: 164

    Topics: Animals; Benzofurans; Chromatography, High Pressure Liquid; Mass Spectrometry; Snails; Sugar Alcohols; Usnea

2019
Usnic Acid Potassium Salt: Evaluation of the Acute Toxicity and Antinociceptive Effect in Murine Model.
    Molecules (Basel, Switzerland), 2019, May-28, Volume: 24, Issue:11

    Topics: Analgesics; Animals; Behavior, Animal; Benzofurans; Disease Models, Animal; Drinking Behavior; Feeding Behavior; Female; Mice; Molecular Conformation; Organ Specificity; Toxicity Tests, Acute

2019
Discovery of novel (+)-Usnic acid derivatives as potential anti-leukemia agents with pan-Pim kinases inhibitory activity.
    Bioorganic chemistry, 2019, Volume: 89

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Benzofurans; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Molecular Docking Simulation; Phosphorylation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-pim-1; Signal Transduction; Stereoisomerism

2019
Glucosylated liposomes as drug delivery systems of usnic acid to address bacterial infections.
    Colloids and surfaces. B, Biointerfaces, 2019, Sep-01, Volume: 181

    Topics: Anti-Bacterial Agents; Bacterial Infections; Benzofurans; Biofilms; Drug Delivery Systems; Glycosylation; Liposomes; Microbial Sensitivity Tests; Molecular Structure; Particle Size; Staphylococcus epidermidis; Surface Properties

2019
Synthesis and cytotoxic evaluation of usnic acid benzylidene derivatives as potential anticancer agents.
    Natural product research, 2021, Volume: 35, Issue:7

    Topics: Antineoplastic Agents; Benzofurans; Benzylidene Compounds; Carbon-13 Magnetic Resonance Spectroscopy; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; HEK293 Cells; Humans; K562 Cells; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship

2021
Mycousfurans A and B, Antibacterial Usnic Acid Congeners from the Fungus
    Marine drugs, 2019, Jul-19, Volume: 17, Issue:7

    Topics: Anti-Bacterial Agents; Ascomycota; Benzofurans; Furans; Geologic Sediments; Heterocyclic Compounds, 3-Ring; Microbial Sensitivity Tests; Micrococcaceae; Molecular Structure; Staphylococcus aureus

2019
Synthesis and Biological Evaluation of (+)-Usnic Acid Derivatives as Potential Anti-
    Journal of agricultural and food chemistry, 2019, Aug-28, Volume: 67, Issue:34

    Topics: Animals; Antiprotozoal Agents; Benzofurans; Drug Evaluation, Preclinical; Female; HeLa Cells; Humans; Mice; Molecular Structure; Toxoplasma; Toxoplasmosis

2019
Development and validation of a reliable LC-MS/MS method for quantitative analysis of usnic acid in Cladonia uncialis.
    BMC research notes, 2019, Aug-30, Volume: 12, Issue:1

    Topics: Benzofurans; Biological Assay; Chromatography, Liquid; Lichens; Reference Standards; Tandem Mass Spectrometry

2019
In vitro activity of usnic acid potassium salt against different developmental stages of Schistosoma mansoni: An ultrastructural study.
    Acta tropica, 2020, Volume: 201

    Topics: Animals; Benzofurans; Cell Survival; Microscopy, Electron, Scanning; Schistosoma mansoni

2020
Determination of Dysregulated miRNA Expression Levels by qRT-PCR after the Application of Usnic Acid to Breast Cancer.
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:5

    Topics: Antineoplastic Agents; Benzofurans; Breast Neoplasms; Cell Proliferation; Computational Biology; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; MicroRNAs; Molecular Structure; Real-Time Polymerase Chain Reaction; Structure-Activity Relationship; Tumor Cells, Cultured

2020
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
    Molecules (Basel, Switzerland), 2019, Oct-15, Volume: 24, Issue:20

    Topics: Benzofurans; Cell Survival; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; Structure-Activity Relationship; Thiazoles

2019
Potassium usnate, a water-soluble usnic acid salt, shows enhanced activity against Schistosoma mansoni in vitro.
    Experimental parasitology, 2020, Volume: 208

    Topics: Analysis of Variance; Animals; Anthelmintics; Benzofurans; Dose-Response Relationship, Drug; Female; Fertility; Male; Mice; Movement; Photomicrography; Schistosoma mansoni; Schistosomiasis mansoni; Time Factors

2020
Structure and Chemical Analysis of Major Specialized Metabolites Produced by the Lichen Evernia prunastri.
    Chemistry & biodiversity, 2020, Volume: 17, Issue:1

    Topics: Benzofurans; Hydroxybenzoates; Lichens; Models, Molecular; Salicylates

2020
Usnic acid induces apoptosis in human gastric cancer cells through ROS generation and DNA damage and causes up-regulation of DNA-PKcs and γ-H2A.X phosphorylation.
    Chemico-biological interactions, 2020, Jan-05, Volume: 315

    Topics: Animals; Apoptosis; Benzofurans; Cell Line; Cell Line, Tumor; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Female; HEK293 Cells; Histones; Humans; Mice; Mice, Inbred C57BL; Phosphorylation; Reactive Oxygen Species; Stomach Neoplasms; Up-Regulation

2020
Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents.
    Journal of natural products, 2020, 01-24, Volume: 83, Issue:1

    Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacillus subtilis; Benzofurans; Lichens; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Triazoles

2020
Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors.
    European journal of medicinal chemistry, 2020, Feb-01, Volume: 187

    Topics: Alzheimer Disease; Animals; Benzofurans; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Lipopolysaccharides; Male; Maze Learning; Mice; Models, Molecular; Molecular Structure; Nitric Oxide; Protein Aggregates; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; tau Proteins

2020
Anti-inflammatory effects of usnic acid in an MPTP-induced mouse model of Parkinson's disease.
    Brain research, 2020, 03-01, Volume: 1730

    Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Brain; Disease Models, Animal; Dopaminergic Neurons; Encephalitis; Male; Mice, Inbred C57BL; Neuroglia; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Rotarod Performance Test

2020
(+)-Usnic Acid Induces ROS-dependent Apoptosis via Inhibition of Mitochondria Respiratory Chain Complexes and Nrf2 Expression in Lung Squamous Cell Carcinoma.
    International journal of molecular sciences, 2020, Jan-29, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzofurans; Carcinoma, Squamous Cell; Cell Line, Tumor; Electron Transport Chain Complex Proteins; Humans; Lung Neoplasms; Mice; Mitochondria; NF-E2-Related Factor 2; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Transplantation, Heterologous

2020
Identification of photodegraded derivatives of usnic acid with improved toxicity profile and UVA/UVB protection in normal human L02 hepatocytes and epidermal melanocytes.
    Journal of photochemistry and photobiology. B, Biology, 2020, Volume: 205

    Topics: Benzofurans; Cell Line; Cell Survival; Hepatocytes; Humans; Melanocytes; Monophenol Monooxygenase; Photolysis; Ultraviolet Rays

2020
Usnic acid as calcium ionophore and mast cells stimulator.
    Biochimica et biophysica acta. Biomembranes, 2020, 09-01, Volume: 1862, Issue:9

    Topics: 2,4-Dinitrophenol; Animals; Benzofurans; Calcimycin; Calcium Ionophores; Cell Line, Tumor; Erythrocytes; Humans; Ion Transport; Lichens; Mitochondria; Oxidative Phosphorylation; Protons; Rats

2020
Derivatives of usnic acid cause cytostatic effect in Caco-2 cells.
    Natural product research, 2021, Volume: 35, Issue:23

    Topics: Benzofurans; Caco-2 Cells; Cell Cycle; Cytostatic Agents; Humans

2021
miR-185-5p response to usnic acid suppresses proliferation and regulating apoptosis in breast cancer cell by targeting Bcl2.
    Biological research, 2020, May-04, Volume: 53, Issue:1

    Topics: Apoptosis; Benzofurans; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection

2020
Antimicrobial Hyperbranched Polymer-Usnic Acid Complexes through a Combined ROP-RAFT Strategy.
    Macromolecular rapid communications, 2020, Volume: 41, Issue:18

    Topics: Anti-Infective Agents; Benzofurans; Polymerization; Polymers

2020
Correlation of Physicochemical and Antimicrobial Properties of Liposomes Loaded with (+)-Usnic Acid.
    ChemPlusChem, 2020, Volume: 85, Issue:5

    Topics: Anti-Infective Agents; Benzofurans; Dimyristoylphosphatidylcholine; Drug Liberation; Liposomes; Microbial Sensitivity Tests; Staphylococcus aureus; Thermodynamics

2020
Bactericidal Activity of Usnic Acid-Chitosan Nanoparticles against Persister Cells of Biofilm-Forming Pathogenic Bacteria.
    Marine drugs, 2020, May-20, Volume: 18, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Benzofurans; Biofilms; Chitosan; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Nanoparticles

2020
Cytotoxicity of Potassium Salts of (+)- and (-) Usnic Acid for Paramecium caudatum.
    Bulletin of experimental biology and medicine, 2020, Volume: 169, Issue:1

    Topics: Animals; Benzofurans; Dose-Response Relationship, Drug; Molecular Conformation; Oxidative Stress; Paramecium caudatum; Potassium; Salts; Structure-Activity Relationship; Toxicity Tests

2020
Biochemical profiles of rat primary cultured hepatocytes following treatment with rotenone, FCCP, or (+)-usnic acid.
    The Journal of toxicological sciences, 2020, Volume: 45, Issue:6

    Topics: Animals; Benzofurans; Bile Acids and Salts; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Chromatography, Liquid; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glycogen; Glycolysis; Hepatocytes; Metabolomics; Mitochondria, Liver; Oxidative Stress; Rats, Inbred F344; Rotenone

2020
The expression profiles of apoptosis-related genes induced usnic acid in SK-BR-3 breast cancer cell.
    Human & experimental toxicology, 2020, Volume: 39, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Breast Neoplasms; Caspase 3; Caspase 9; Cell Line; Cell Proliferation; Cell Survival; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Proto-Oncogene Proteins c-bcl-2

2020
Gelatin-based membrane containing usnic acid-loaded liposomes: A new treatment strategy for corneal healing.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 130

    Topics: Administration, Ophthalmic; Animals; Benzofurans; Chickens; Cicatrix; Cornea; Drug Delivery Systems; Female; Gelatin; Liposomes; Neovascularization, Physiologic; Ophthalmic Solutions; Wound Healing

2020
Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.
    Journal of natural products, 2020, 08-28, Volume: 83, Issue:8

    Topics: Benzofurans; Crystallography, X-Ray; HeLa Cells; Humans; Hydrogen Bonding; Models, Molecular; Molecular Structure; Monoterpenes; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Spectrum Analysis; Structure-Activity Relationship

2020
Usnic Acid Inhibits Proliferation and Migration through ATM Mediated DNA Damage Response in RKO Colorectal Cancer Cell.
    Current pharmaceutical biotechnology, 2021, Volume: 22, Issue:8

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Autophagy; Benzofurans; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; DNA Damage; Drug Therapy, Combination; Humans; Hydrogen Peroxide; MicroRNAs; Signal Transduction; Up-Regulation; Wound Healing

2021
Usnic acid enantiomers restore cognitive deficits and neurochemical alterations induced by Aβ
    Behavioural brain research, 2021, 01-15, Volume: 397

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Benzofurans; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Inflammation; Injections, Intraventricular; Interleukin-1beta; Mice; Molecular Docking Simulation; Nootropic Agents; Peptide Fragments

2021
Inclusion complex with β-cyclodextrin is a key determining factor for the cardioprotection induced by usnic acid.
    Chemico-biological interactions, 2020, Dec-01, Volume: 332

    Topics: Animals; Benzofurans; beta-Cyclodextrins; Cardiotonic Agents; Male; Myocardial Reperfusion Injury; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Thermogravimetry

2020
Lichen-associated bacteria transform antibacterial usnic acid to products of lower antibiotic activity.
    Phytochemistry, 2021, Volume: 181

    Topics: Anti-Bacterial Agents; Benzofurans; Lichens; Streptomyces

2021
Genome-Wide Analysis of Biosynthetic Gene Cluster Reveals Correlated Gene Loss with Absence of Usnic Acid in Lichen-Forming Fungi.
    Genome biology and evolution, 2020, 10-01, Volume: 12, Issue:10

    Topics: Benzofurans; Evolution, Molecular; Gene Rearrangement; Genome, Fungal; Lichens; Multigene Family; Parmeliaceae; Phylogeny; Polyketide Synthases

2020
Are atranols the only skin sensitizers in oakmoss? A systematic investigation using non-animal methods.
    Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 70

    Topics: Animal Testing Alternatives; Benzaldehydes; Benzofurans; Cell Line; Haptens; Humans; Resins, Plant; Resorcinols; Terpenes

2021
Usnic-Acid-Functionalized Silk Fibroin Composite Scaffolds for Cutaneous Wounds Healing.
    Macromolecular bioscience, 2021, Volume: 21, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Benzofurans; Biocompatible Materials; Fibroins; Keratin-10; Male; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Skin; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Tensile Strength; Tissue Scaffolds; Vascular Endothelial Growth Factor A; Wound Healing

2021
Usnic acid deteriorates acidogenicity, acidurance and glucose metabolism of Streptococcus mutans through downregulation of two-component signal transduction systems.
    Scientific reports, 2021, 01-14, Volume: 11, Issue:1

    Topics: Bacterial Proteins; Benzofurans; Dental Caries; Down-Regulation; Gene Expression Regulation, Bacterial; Glucose; Humans; Oxidative Stress; Signal Transduction; Streptococcus mutans

2021
PORIMIN: The key to (+)-Usnic acid-induced liver toxicity and oncotic cell death in normal human L02 liver cells.
    Journal of ethnopharmacology, 2021, Apr-24, Volume: 270

    Topics: Animals; Anti-Infective Agents; Benzofurans; Caspase Inhibitors; Caspases; Cell Death; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Gene Knockdown Techniques; Glutathione; Hepatocytes; Humans; Intracellular Signaling Peptides and Proteins; Ischemia; JNK Mitogen-Activated Protein Kinases; Liver; Mice, Inbred ICR; Necrosis; Oxidative Stress; Phosphate-Binding Proteins; Receptors, Cell Surface

2021
α-Glucosidase Inhibition by Usnic Acid Derivatives.
    Chemistry & biodiversity, 2021, Volume: 18, Issue:4

    Topics: alpha-Glucosidases; Benzofurans; Glycoside Hydrolase Inhibitors; Humans; Molecular Docking Simulation; Molecular Structure

2021
Antibacterial activity of usnic acid from Usnea longissima Ach.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:4

    Topics: Anti-Bacterial Agents; Benzofurans; Escherichia coli; Parmeliaceae; Salmonella typhi; Staphylococcus aureus

2020
(+)-Usnic acid modulates the Nrf2-ARE pathway in FaDu hypopharyngeal carcinoma cells.
    Molecular and cellular biochemistry, 2021, Volume: 476, Issue:6

    Topics: Antioxidant Response Elements; Benzofurans; Cell Line, Tumor; Humans; Hypopharyngeal Neoplasms; Neoplasm Proteins; NF-E2-Related Factor 2; Signal Transduction

2021
Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD-L1 expression and enhancing T-lymphocyte tumor-killing activity.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:7

    Topics: B7-H1 Antigen; Benzofurans; Cell Line, Tumor; Cell Proliferation; HeLa Cells; Humans; Parmeliaceae; T-Lymphocytes

2021
Alkoxy glycerol enhanced activity of Oxyresveratrol in Alzheimer's disease by rescuing Tau protein.
    Neuroscience letters, 2021, 08-10, Volume: 759

    Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Behavior, Animal; Benzofurans; Drosophila melanogaster; Glycerol; Humans; Learning; Memory; Neuroprotective Agents; Plant Extracts; Stilbenes; tau Proteins

2021
Anomalous potentials on bilayer lipid membranes in the presence of usnic acid: Markin-Sokolov versus Nernst-Donnan equilibrium.
    Bioelectrochemistry (Amsterdam, Netherlands), 2021, Volume: 141

    Topics: Benzofurans; Calcium; Cations, Divalent; Ionophores; Lipid Bilayers; Magnesium; Membrane Potentials

2021
New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.
    Biomolecules, 2021, 07-01, Volume: 11, Issue:7

    Topics: Benzofurans; HEK293 Cells; Humans; Monoterpenes; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases

2021
The influence of an enamine usnic acid derivative (a tyrosyl-DNA phosphodiesterase 1 inhibitor) on the therapeutic effect of topotecan against transplanted tumors in vivo.
    Clinical & experimental metastasis, 2021, Volume: 38, Issue:5

    Topics: Animals; Benzofurans; Carcinoma, Lewis Lung; Female; Male; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Topotecan

2021
Transcriptome analysis upon potassium usnate exposure reveals ATF3-induced apoptosis in human gastric and colon cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 91

    Topics: Activating Transcription Factor 3; Animals; Apoptosis; Benzofurans; Cell Line, Tumor; Colonic Neoplasms; Endoplasmic Reticulum Stress; Gene Expression Profiling; Humans; Mice; Potassium; Stomach Neoplasms

2021
Molecular docking and inhibition studies of vulpinic, carnosic and usnic acids on polyol pathway enzymes.
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:22

    Topics: Animals; Benzofurans; L-Iditol 2-Dehydrogenase; Molecular Docking Simulation; Polymers; Sheep

2022
(+)-Usnic Acid as a Promising Candidate for a Safe and Stable Topical Photoprotective Agent.
    Molecules (Basel, Switzerland), 2021, Aug-28, Volume: 26, Issue:17

    Topics: Acrylates; Benzofurans; Fibroblasts; Humans; Keratinocytes; Melanocytes; Radiation-Protective Agents; Skin; Ultraviolet Rays

2021
Quantitative variations of usnic acid and selected elements in terricolous lichen Cladonia mitis Sandst., with respect to different environmental factors - A chemometric approach.
    Phytochemistry, 2021, Volume: 192

    Topics: Ascomycota; Benzofurans; Lichens; Metals, Heavy

2021
Fucoidan-Coated Liposomes: A Target System to Deliver the Antimicrobial Drug Usnic Acid to Macrophages Infected with
    Journal of biomedical nanotechnology, 2021, 08-01, Volume: 17, Issue:8

    Topics: Anti-Infective Agents; Benzofurans; Liposomes; Macrophages; Mycobacterium tuberculosis; Polysaccharides

2021
Effect of Elicitation with (+)-Usnic Acid on Accumulation of Phenolic Acids and Flavonoids in Agitated Microshoots of
    Molecules (Basel, Switzerland), 2021, Sep-12, Volume: 26, Issue:18

    Topics: 3,4-Dihydroxyphenylacetic Acid; Benzofurans; Biomass; Caffeic Acids; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Eryngium; Flavonoids; Hydroxybenzoates; Plant Growth Regulators; Plant Shoots; Quercetin; Rosmarinic Acid

2021
Evaluation of the Antimicrobial Efficacy of
    International journal of molecular sciences, 2021, Oct-20, Volume: 22, Issue:21

    Topics: Acetylcysteine; Anti-Bacterial Agents; Anti-Infective Agents; Benzofurans; Biofilms; Cell Line; Escherichia coli; Food Contamination; Food Microbiology; Foodborne Diseases; Glycolipids; Humans; Listeria monocytogenes; Microbial Sensitivity Tests; Salmonella enterica; Staphylococcus aureus

2021
Potential of Usnic Acid Compound from Lichen Genus Usnea sp. as Antidiabetic Agents.
    Journal of oleo science, 2022, Volume: 71, Issue:1

    Topics: Benzofurans; Biological Products; Crystallization; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Usnea

2022
Anti-ageing and Anti-lung Carcinoma Effects of Vulpinic Acid and Usnic Acid Compounds and Biological Investigations with Molecular Modeling Study.
    Journal of oleo science, 2022, Volume: 71, Issue:2

    Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Collagenases; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Furans; Geroscience; Humans; Lung Neoplasms; Models, Molecular; Pancreatic Elastase; Phenylacetates; Skin Aging

2022
The Isoxazole Derivative of Usnic Acid Induces an ER Stress Response in Breast Cancer Cells That Leads to Paraptosis-like Cell Death.
    International journal of molecular sciences, 2022, Feb-04, Volume: 23, Issue:3

    Topics: Animals; Apoptosis; Benzofurans; Breast Neoplasms; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum Stress; Female; Humans; Isoxazoles; Mice; Mice, Nude

2022
Usnic acid induced changes in biomolecules and their association with apoptosis in squamous carcinoma (A-431) cells: A flow cytometry, FTIR and DLS spectroscopic study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, Jun-05, Volume: 274

    Topics: Amides; Apoptosis; Benzofurans; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA; Flow Cytometry; Humans; Spectroscopy, Fourier Transform Infrared

2022
Novel methods to characterise spatial distribution and enantiomeric composition of usnic acids in four Icelandic lichens.
    Phytochemistry, 2022, Volume: 200

    Topics: Anti-Bacterial Agents; Benzofurans; Iceland; Lichens

2022
Antimelanoma Potential of Cladonia mitis Acetone Extracts - Comparative in Vitro Studies in Relation to Usnic Acid Content.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:7

    Topics: Acetone; Antineoplastic Agents; Ascomycota; Benzofurans; Humans; Lichens; Melanoma

2022
Enhanced wound-healing capability with inherent antimicrobial activities of usnic acid incorporated poly(ε-caprolactone)/decellularized extracellular matrix nanofibrous scaffold.
    Biomaterials advances, 2022, Volume: 140

    Topics: Anti-Bacterial Agents; Benzofurans; Decellularized Extracellular Matrix; Humans; Nanofibers; Polyesters; Tissue Scaffolds; Wound Healing; Wound Infection

2022
Toxicity studies of (+)-usnic acid administered in feed to F344/N Nctr rats and B6C3F1/Nctr mice.
    Toxicity report series, 2022, Issue:104

    Topics: Animals; Anti-Obesity Agents; Benzofurans; Female; Male; Mice; Mice, Inbred Strains; Protons; Rats; Rats, Inbred F344; Usnea

2022
Toxicity studies of Usnea lichens containing (+/-)-usnic acid administered in feed to F344/N Nctr rats and B6C3F1/Nctr mice.
    Toxicity report series, 2022, Issue:105

    Topics: Animals; Anti-Obesity Agents; Benzofurans; Female; Lichens; Male; Mice; Mice, Inbred Strains; Protons; Rats; Rats, Inbred F344; Usnea

2022
Divergent reactivity of usnic acid and evaluation of its derivatives for antiproliferative activity against cancer cells.
    Bioorganic & medicinal chemistry, 2023, 02-01, Volume: 79

    Topics: Benzofurans; HeLa Cells; Humans; Lichens; Neoplasms

2023