ursolic acid has been researched along with glycyrrhetinic acid in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 15 (68.18) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, K; Bastow, KF; Itokawa, H; Lee, KH; Morris-Natschke, SL; Nakagawa-Goto, K; Taniguchi, M; Tatsuzaki, J | 1 |
| Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE | 1 |
| Barda, Y; Kisselev, OG; Marshall, GR; Taylor, CM | 1 |
| Hong, D; Hu, LH; Li, J; Li, JY; Shen, Q; Shi, L; Zhang, W; Zhang, YN | 1 |
| Amano, F; Hamashima, Y; Hasegawa, J; Kajimoto, T; Katoh, K; Node, M; Takebe, Y; Tanaka, R; Tsujii, H; Yamada, T | 1 |
| El-Kabbani, O; Endo, S; Hara, A; Iinuma, M; Matsunaga, T; Soda, M; Tajima, K; Takemura, M; Zhao, HT | 1 |
| Gatbonton-Schwager, TN; Letterio, JJ; Tochtrop, GP | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Chen, K; Huang, X; Peng, Y; Qiu, Y; Shi, Y; Sun, D; Wang, H; Wang, Q; Xiao, S; Yu, F; Yu, M; Zhang, C; Zhang, L; Zhang, Z; Zhao, C; Zheng, Y; Zhou, D; Zhu, L | 1 |
| Csuk, R; Heller, L; Köwitsch, A; Perl, V; Schwarz, S; Siewert, B | 1 |
| Fan, Z; Han, X; Jiao, P; Peng, Y; Wan, C; Wang, H; Wang, Q; Xiao, S; Xu, R; Yu, F; Zhang, L; Zhang, Y; Zhou, D; Zhou, X | 1 |
| Feng, B; Hou, XY; Shi, JJ; Zhang, CL; Zhao, CH; Zhao, LX | 1 |
| Csuk, R; Heller, L; Kerzig, C; Kramell, AE; Sommerwerk, S | 1 |
| Dong, YS; Sun, WL; Wen, C; Xing, Y; Xiu, ZL; Yu, XX; Zhang, BW | 1 |
| Huang, H; Li, Z; Liu, R; Min, Q; Zhu, Q; Zhu, Y | 1 |
| Efdi, M; Itoh, T; Katsurayama, K; Koketsu, M; Ninomiya, M | 1 |
| Appendino, G; Bellido, ML; Calzado, MA; Caprioglio, D; Cruz, C; Galera, N; Jinénez, C; Minassi, A; Muñoz, E; Prados, ME; Rogati, F | 1 |
| Gao, X; Kang, H; Li, B; Liu, N; Liu, S; Liu, T; Liu, X; Long, X; Lu, C; Peng, J; Qi, M; Qin, S; Sun, T; Wei, M; Wei, Y; Xie, M; Xu, Z; Yang, C; Yang, G; Zhang, Z; Zhao, R; Zhou, H; Zhu, L | 1 |
| Cheng, KG; Huang, JY; Liu, CM; Sheng, LX; Wen, XA | 1 |
| Brandes, B; Csuk, R; Fischer, L; Hoenke, S | 1 |
| Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ | 1 |
| Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H | 1 |
22 other study(ies) available for ursolic acid and glycyrrhetinic acid
| Article | Year |
|---|---|
Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.
Topics: Antineoplastic Agents; Cytotoxins; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Styrenes; Tumor Cells, Cultured | 2007 |
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2008 |
Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening.
Topics: Animals; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Heterotrimeric GTP-Binding Proteins; Humans; Receptors, G-Protein-Coupled; Rhodopsin; Signal Transduction; Transducin | 2008 |
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Insulin; Obesity; Oleanolic Acid; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Structure-Activity Relationship; T-Lymphocytes | 2008 |
Novel 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2)-curcumin, kojic acid, quercetin, and baicalein conjugates as HIV agents.
Topics: Antiviral Agents; Cell Line; Cell Survival; Curcumin; Flavanones; HIV Infections; HIV-1; Humans; Molecular Structure; Pyrones; Quercetin; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; T-Lymphocytes; Triterpenes; Viral Proteins | 2009 |
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; HeLa Cells; HT29 Cells; Humans; Mitomycin; Models, Molecular; Molecular Structure; Mutation; Oleanolic Acid; Pentacyclic Triterpenes | 2011 |
Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Heme Oxygenase-1; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 1; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Triterpenes | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cytotoxins; HEK293 Cells; Hemolytic Agents; Hepacivirus; Humans; Oleanolic Acid; Rabbits; Structure-Activity Relationship; Virus Internalization | 2013 |
Incorporation of a Michael acceptor enhances the antitumor activity of triterpenoic acids.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured | 2015 |
Synthesis and biological evaluation of ring A and/or C expansion and opening echinocystic acid derivatives for anti-HCV entry inhibitors.
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Structure-Activity Relationship | 2015 |
Design, synthesis, and biofunctional evaluation of novel pentacyclic triterpenes bearing O-[4-(1-piperazinyl)-4-oxo-butyryl moiety as antiproliferative agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pentacyclic Triterpenes; Piperazines; Structure-Activity Relationship | 2015 |
Rhodamine B conjugates of triterpenoic acids are cytotoxic mitocans even at nanomolar concentrations.
Topics: Animals; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mitochondria; NIH 3T3 Cells; Rhodamines; Structure-Activity Relationship; Triterpenes | 2017 |
Pentacyclic triterpenes as α-glucosidase and α-amylase inhibitors: Structure-activity relationships and the synergism with acarbose.
Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Drug Synergism; Inhibitory Concentration 50; Kinetics; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2017 |
Design, synthesis and biological evaluation of seco-A-pentacyclic triterpenoids-3,4-lactone as potent non-nucleoside HBV inhibitors.
Topics: Antiviral Agents; DNA Replication; Dose-Response Relationship, Drug; Drug Design; Hepatitis B Surface Antigens; Hepatitis B virus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triterpenes | 2018 |
Sentulic acid isolated from Sandoricum koetjape Merr attenuates lipopolysaccharide and interferon gamma co-stimulated nitric oxide production in murine macrophage RAW264 cells.
Topics: Animals; Cyclooxygenase 2; Down-Regulation; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Macrophages; Meliaceae; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptors; Triterpenes; Tumor Necrosis Factor-alpha | 2018 |
Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors.
Topics: Enzyme Inhibitors; HEK293 Cells; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; NF-kappa B; Triterpenes | 2018 |
Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.
Topics: Antineoplastic Agents; Apoptosis; Biological Products; Caspases; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chemistry Techniques, Synthetic; Drug Design; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Neoplastic Stem Cells; Reactive Oxygen Species; Triterpenes | 2018 |
Synthesis and antitumor activity of fluorouracil - oleanolic acid/ursolic acid/glycyrrhetinic acid conjugates.
Topics: | 2019 |
Design, synthesis and cytotoxicity of BODIPY FL labelled triterpenoids.
Topics: Antineoplastic Agents; Boron Compounds; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Triterpenes | 2020 |
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship | 2019 |
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha | 2021 |