Page last updated: 2024-08-23

ursodeoxycholic acid and transforming growth factor beta

ursodeoxycholic acid has been researched along with transforming growth factor beta in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Fan, G; Kren, BT; Ma, X; Rodrigues, CM; Steer, CJ1
Fan, G; Kren, BT; Linehan-Stieers, C; Ma, X; Rodrigues, CM; Steer, CJ1
Angulo, P; Dickson, ER; Haber, J; Jorgensen, R; Katz, G; Lindor, K; Malkiewicz, I; Neuman, M; Shear, N1
Castro, RE; Kren, BT; Ma, X; Rodrigues, CM; Sola, S; Steer, CJ1
Castro, RE; Kren, BT; Rodrigues, CM; Solá, S; Steer, CJ1
Amaral, JD; Borralho, PM; Castro, RE; Kren, BT; Ramalho, RM; Rodrigues, CM; Solá, S; Steer, CJ; Tanaka, H1
Cai, Z; Chen, J; Chen, T; Guo, J; Li, X; Lin, A; Lu, C; Ma, Z; Qiao, C; Shen, Y; Song, Z; Wang, J; Zeng, X; Zhang, C1
Chen, R; Chen, Y; Fang, J; Gershwin, ME; Helleday, T; Huang, B; Li, B; Li, Y; Lian, M; Lian, Z; Liang, J; Liu, Q; Lyu, Z; Ma, X; Miao, Q; Qian, Q; Tang, R; Wang, Q; Xiao, X; You, Z; Zhang, J1

Trials

1 trial(s) available for ursodeoxycholic acid and transforming growth factor beta

ArticleYear
Tumor necrosis factor-alpha and transforming growth factor-beta reflect severity of liver damage in primary biliary cirrhosis.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:2

    Topics: Adult; Biomarkers; Biopsy; Cholagogues and Choleretics; Cholangitis, Sclerosing; Double-Blind Method; Female; Hepatitis C; Humans; Liver; Liver Cirrhosis, Biliary; Liver Diseases, Alcoholic; Male; Middle Aged; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2002

Other Studies

7 other study(ies) available for ursodeoxycholic acid and transforming growth factor beta

ArticleYear
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation.
    The Journal of clinical investigation, 1998, Jun-15, Volume: 101, Issue:12

    Topics: Animals; Apoptosis; Cell Membrane; Cholagogues and Choleretics; Deoxycholic Acid; Ethanol; Fas Ligand Protein; Liver; Male; Membrane Glycoproteins; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ursodeoxycholic Acid

1998
Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation.
    Cell death and differentiation, 1999, Volume: 6, Issue:9

    Topics: Animals; Apoptosis; Caspases; Cell Polarity; Cytochrome c Group; Deoxycholic Acid; Enzyme Activation; Intracellular Membranes; Liver; Male; Mitochondria, Liver; Okadaic Acid; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ursodeoxycholic Acid

1999
Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes.
    The Journal of biological chemistry, 2003, Dec-05, Volume: 278, Issue:49

    Topics: Animals; Apoptosis; Base Sequence; Caspases; Cell Cycle Proteins; Cells, Cultured; DNA Primers; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Hepatocytes; Male; Rats; Rats, Sprague-Dawley; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Protein p53; Ursodeoxycholic Acid

2003
Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes.
    Biochemistry, 2004, Jul-06, Volume: 43, Issue:26

    Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Caspases; Cell Cycle Proteins; Cell Nucleus; Cytosol; Densitometry; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Activation; Hepatocytes; Immunoblotting; Male; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Transcription Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Protein p53; Ursodeoxycholic Acid

2004
Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes.
    Hepatology (Baltimore, Md.), 2005, Volume: 42, Issue:4

    Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Cells, Cultured; Gene Expression; Hepatocytes; HSP90 Heat-Shock Proteins; Male; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ursodeoxycholic Acid

2005
Ursodeoxycholic acid reduces antitumor immunosuppression by inducing CHIP-mediated TGF-β degradation.
    Nature communications, 2022, 06-14, Volume: 13, Issue:1

    Topics: Animals; Cell Line, Tumor; Humans; Immunosuppression Therapy; Mice; Neoplasms; Retrospective Studies; Transforming Growth Factor beta; Ursodeoxycholic Acid

2022
NUDT1 promotes the accumulation and longevity of CD103
    Journal of hepatology, 2022, Volume: 77, Issue:5

    Topics: Animals; Autoantigens; CD8-Positive T-Lymphocytes; Immunodominant Epitopes; Liver Cirrhosis, Biliary; Mice; Oxidoreductases; Pyruvates; Transforming Growth Factor beta; Ursodeoxycholic Acid

2022