Page last updated: 2024-08-23

ursodeoxycholic acid and acetylcysteine

ursodeoxycholic acid has been researched along with acetylcysteine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's5 (25.00)29.6817
2010's10 (50.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Niu, N; Smith, BF1
Salmerón Escobar, FJ1
Giostra, E; Malè, PJ1
Attali, M; Borchardt, J; Mahlab, K; Malnick, SD; Sokolowski, N1
Al-Osaimi, AM; Argo, CK; Caldwell, SH; Chang, CY1
Dhawan, A; Dziechciarz, P; Horvath, A; Socha, P; Szajewska, H; Vajro, P1
Cooper, J; Webster, CR1
Akkiz, H; Cosar, A; Kece, C; Ozdil, B; Sandikci, M1
Li, YC; Zhou, TF1
Abakumov, VZ; Belonovskaia, EB; Buko, VU; Lukivskaia, OIa; Naruta, EE1
Clemens, DL; Dey, A; Kumar, SM; Swaminathan, K1
Abdel-Latif, HA; Ali, MH; Messiha, BA1
Cotrim, HP; Oliveira, CP; Parise, ER; Salgado, ALA; Siqueira, ACG; Stefano, JT1
Björklund, A; El-Serafi, I; Mattsson, J; Remberger, M; Ringdèn, O; Sundin, M; Törlén, J; Winiarski, J1
Aithal, GP; Alvarez-Alvarez, I; Andrade, RJ; Arikan, C; Atallah, E; Lucena, MI; Medina-Caliz, I; Niu, H1

Reviews

7 review(s) available for ursodeoxycholic acid and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Alternative treatment to interferon therapy in chronic viral hepatitis].
    Gastroenterologia y hepatologia, 1995, Volume: 18, Issue:8

    Topics: Acetylcysteine; Adjuvants, Immunologic; Antisense Elements (Genetics); Antiviral Agents; Cholagogues and Choleretics; Hepatitis B; Hepatitis C; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Interferon Inducers; Poly A-U; RNA, Catalytic; Ursodeoxycholic Acid

1995
[Treatment of viral hepatitis C: what are the perspectives?].
    Revue medicale de la Suisse romande, 1994, Volume: 114, Issue:9

    Topics: Acetylcysteine; Adult; Age Factors; Drug Therapy, Combination; Female; Hepatitis C; Humans; Interferon-alpha; Ketoprofen; Male; Middle Aged; Prognosis; Ribavirin; Sex Factors; Time Factors; Ursodeoxycholic Acid

1994
Therapy of NAFLD: antioxidants and cytoprotective agents.
    Journal of clinical gastroenterology, 2006, Volume: 40 Suppl 1

    Topics: Acetylcysteine; Antioxidants; Betaine; Cholagogues and Choleretics; Disease Progression; Fatty Liver; Humans; Lipid Peroxidation; S-Adenosylmethionine; Ursodeoxycholic Acid; Vitamin E

2006
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review.
    Journal of pediatric gastroenterology and nutrition, 2009, Volume: 48, Issue:5

    Topics: Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fatty Liver; Humans; Hypoglycemic Agents; Liver; Metformin; Pioglitazone; Probucol; Randomized Controlled Trials as Topic; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E

2009
Therapeutic use of cytoprotective agents in canine and feline hepatobiliary disease.
    The Veterinary clinics of North America. Small animal practice, 2009, Volume: 39, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Biliary Tract Diseases; Cat Diseases; Cats; Cholagogues and Choleretics; Cryoprotective Agents; Dog Diseases; Dogs; Free Radical Scavengers; Liver Diseases; S-Adenosylmethionine; Silymarin; Ursodeoxycholic Acid; Vitamin E

2009
Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review.
    Drug safety, 2022, Volume: 45, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adrenal Cortex Hormones; Adult; Carnitine; Chemical and Drug Induced Liver Injury; Child; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glycyrrhizic Acid; Humans; Infant, Newborn; Liver; Liver Failure, Acute; Retrospective Studies; S-Adenosylmethionine; Ursodeoxycholic Acid

2022

Trials

1 trial(s) available for ursodeoxycholic acid and acetylcysteine

ArticleYear
N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL.
    Arquivos de gastroenterologia, 2019, Aug-13, Volume: 56, Issue:2

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Treatment Outcome; Ursodeoxycholic Acid; Young Adult

2019

Other Studies

12 other study(ies) available for ursodeoxycholic acid and acetylcysteine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Addition of N-acetylcysteine to aqueous model bile systems accelerates dissolution of cholesterol gallstones.
    Gastroenterology, 1990, Volume: 98, Issue:2

    Topics: Acetylcysteine; Animals; Bile; Cattle; Cholelithiasis; Cholesterol; Expectorants; Humans; In Vitro Techniques; Taurocholic Acid; Ursodeoxycholic Acid

1990
Acute cholestatic hepatitis after exposure to isoflurane.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:2

    Topics: Acetylcysteine; Acute Disease; Aged; Anesthetics, Inhalation; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Isoflurane; Liver; Liver Function Tests; Ursodeoxycholic Acid

2002
New therapeutic option with N-acetylcysteine for primary sclerosing cholangitis: two case reports.
    American journal of therapeutics, 2011, Volume: 18, Issue:3

    Topics: Acetylcysteine; Adult; Cholagogues and Choleretics; Cholangitis, Sclerosing; Female; Free Radical Scavengers; Humans; Liver; Male; Ursodeoxycholic Acid; Young Adult

2011
[Three schistosomiasis patients combined with acute hepatitis E].
    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 2011, Volume: 23, Issue:6

    Topics: Acetylcysteine; Drug Therapy, Combination; Drugs, Chinese Herbal; Hepatitis E; Humans; Male; Middle Aged; Schistosomiasis; Ursodeoxycholic Acid

2011
[Preventive administration of new UDCA derivatives in experimental alcoholic steatohepatitis].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:1

    Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Cholagogues and Choleretics; Diet; Ethanol; Fatty Liver, Alcoholic; Female; gamma-Glutamyltransferase; Liver; Protective Agents; Rats; Rats, Wistar; Triglycerides; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2013
GSH protects against oxidative stress and toxicity in VL-17A cells exposed to high glucose.
    European journal of nutrition, 2015, Volume: 54, Issue:2

    Topics: Acetylcysteine; Alcohol Dehydrogenase; Antimetabolites; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Survival; Clone Cells; Cytochrome P-450 CYP2E1; Glucose; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Hyperglycemia; Lactoylglutathione Lyase; Maleates; Oxidative Stress; Reactive Oxygen Species; Recombinant Proteins; Ursodeoxycholic Acid

2015
Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.
    Pharmaceutical biology, 2016, Volume: 54, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Choline Deficiency; Cytoprotection; Disease Models, Animal; Hypolipidemic Agents; Lipids; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Ursodeoxycholic Acid

2016
Reduced Risk of Sinusoidal Obstruction Syndrome of the Liver after Busulfan-Cyclophosphamide Conditioning Prior to Allogeneic Hematopoietic Stem Cell Transplantation.
    Clinical and translational science, 2020, Volume: 13, Issue:2

    Topics: Acetylcysteine; Adolescent; Adult; Busulfan; Capillaries; Child; Child, Preschool; Cholagogues and Choleretics; Cyclophosphamide; Drug Monitoring; Female; Free Radical Scavengers; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Incidence; Infant; Liver; Male; Middle Aged; Myeloablative Agonists; Retrospective Studies; Risk Assessment; Transplantation Conditioning; Ursodeoxycholic Acid; Young Adult

2020