ursocholic acid has been researched along with ursodeoxycholic acid in 12 studies
| Studies (ursocholic acid) | Trials (ursocholic acid) | Recent Studies (post-2010) (ursocholic acid) | Studies (ursodeoxycholic acid) | Trials (ursodeoxycholic acid) | Recent Studies (post-2010) (ursodeoxycholic acid) |
|---|---|---|---|---|---|
| 36 | 4 | 2 | 4,592 | 626 | 1,561 |
| Protein | Taxonomy | ursocholic acid (IC50) | ursodeoxycholic acid (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Sodium/bile acid cotransporter | Homo sapiens (human) | 3.6 | |
| M1-family alanyl aminopeptidase | Plasmodium falciparum 3D7 | 2.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gilmer, JF; Keaveney, R; Kelleher, D; Long, A; Majer, F; Peta, VK; Sharma, R; Wang, J | 1 |
| Akiyoshi, T; Igimi, H; Ishihara, S; Nomura, Y; Takase, H; Uchida, K | 1 |
| Angellotti, MA; Fini, A; Minutello, A; Roda, A | 1 |
| Gurley, EC; Heuman, DM; Hylemon, PB; Kubaska, WM; Mosbach, EH; Vlahcevic, ZR | 1 |
| Holdeman, LV; Macdonald, IA; Sutherland, JD; Williams, CN | 1 |
| Forrest, TP; Hutchison, DM; Macdonald, IA | 1 |
| Aldini, R; Cerrè, C; Montagnani, M; Pellicciari, R; Roda, A; Roda, E | 1 |
| Abroon, J; Batta, AK; Salen, G | 1 |
| Inaba, K; Ishikawa, H; Kashima, K; Mitsuyoshi, H; Nakajima, Y; Nakashima, T; Sakai, M; Sakamoto, Y; Shima, T | 1 |
| Kakisaka, Y; Mitsuyoshi, H; Nakashima, T; Sumida, Y; Yoh, T | 1 |
| Batta, AK; Salen, G; Tint, GS | 1 |
| Poša, M | 1 |
3 trial(s) available for ursocholic acid and ursodeoxycholic acid
| Article | Year |
|---|---|
Ursocholic acid, a hydrophilic bile acid, fails to improve liver function parameters in primary biliary cirrhosis: comparison with ursodeoxycholic acid.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Fasting; Female; Humans; Liver; Liver Cirrhosis, Biliary; Placebos; Taurocholic Acid; Ursodeoxycholic Acid | 1997 |
A paucity of unusual trihydroxy bile acids in the urine of patients with severe liver diseases.
Topics: Acute Disease; Adolescent; Adult; Aged; Cholagogues and Choleretics; Cholic Acids; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged; Reference Values; Severity of Illness Index; Ursodeoxycholic Acid | 1999 |
Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis.
Topics: Adult; Anticholesteremic Agents; Bile; Bile Acids and Salts; Case-Control Studies; Chenodeoxycholic Acid; Cholestanols; Cholesterol; Cholestyramine Resin; Cholic Acids; Homozygote; Humans; Lovastatin; Male; Middle Aged; Ursodeoxycholic Acid; Xanthomatosis, Cerebrotendinous | 2004 |
9 other study(ies) available for ursocholic acid and ursodeoxycholic acid
| Article | Year |
|---|---|
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
Topics: Bile Acids and Salts; Cell Line; Cell Survival; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Esophagus; Humans; Hydrophobic and Hydrophilic Interactions; Structure-Activity Relationship | 2010 |
Differential effects of ursodeoxycholic acid and ursocholic acid on the formation of biliary cholesterol crystals in mice.
Topics: Animals; Bile; Cholelithiasis; Cholesterol; Cholic Acids; Crystallization; Male; Mice; Mice, Inbred ICR; Ursodeoxycholic Acid | 1991 |
Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC.
Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Deoxycholic Acid; Hydrogen-Ion Concentration; Lipids; Octanols; Structure-Activity Relationship; Ursodeoxycholic Acid | 1990 |
Effects of ursodeoxycholic acid, analogues of ursodeoxycholic acid and combination of bile acids on bile acid synthesis in cultured rat hepatocytes.
Topics: Animals; Bile Acids and Salts; Cell Survival; Cells, Cultured; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol Esters; Cholic Acids; Deoxycholic Acid; Feedback; Hydroxy Acids; L-Lactate Dehydrogenase; Liver; Phosphatidylcholines; Rats; Ursodeoxycholic Acid | 1987 |
Formation of urso- and ursodeoxy-cholic acids from primary bile acids by a Clostridium limosum soil isolate.
Topics: Bile Acids and Salts; Cholic Acid; Cholic Acids; Chromatography, Thin Layer; Clostridium; Deoxycholic Acid; Soil Microbiology; Stereoisomerism; Ursodeoxycholic Acid | 1984 |
Formation of urso- and ursodeoxy-cholic acids from primary bile acids by Clostridium absonum.
Topics: Bile Acids and Salts; Carbon Radioisotopes; Cholic Acids; Clostridium; Deoxycholic Acid; Hydroxysteroid Dehydrogenases; Kinetics; Mass Spectrometry; Ursodeoxycholic Acid | 1981 |
Relationship between structure and intestinal absorption of bile acids with a steroid or side-chain modification.
Topics: Animals; Bile Acids and Salts; Biological Transport; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Ileum; Intestinal Absorption; Kinetics; Methylation; Perfusion; Rabbits; Steroids; Structure-Activity Relationship; Taurine; Ursodeoxycholic Acid | 1996 |
Differences in the efficacy of ursodeoxycholic acid and bile acid metabolism between viral liver diseases and primary biliary cirrhosis.
Topics: Adult; Aged; Aspartate Aminotransferases; Bile Acids and Salts; Cholic Acids; Female; gamma-Glutamyltransferase; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid | 2001 |
Heuman indices of hydrophobicity of bile acids and their comparison with a newly developed and conventional molecular descriptors.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, Reverse-Phase; Deoxycholic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Conformation; Principal Component Analysis; Regression Analysis; Ursodeoxycholic Acid | 2014 |