uroporphyrinogen iii and heme

uroporphyrinogen iii has been researched along with heme in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199010 (29.41)18.7374
1990's11 (32.35)18.2507
2000's5 (14.71)29.6817
2010's6 (17.65)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Gidari, AS; Levere, RD1
Walsh, JR1
Beale, SI; Granick, S1
Battersby, AR1
Goldberg, A; Ippen, H; Moore, MR; Seubert, A; Seubert, S; Thompson, GG1
Bestervelt, LL; Christenson, WR; Piper, WN1
Ku, WW; Piper, WN1
Bickers, DR1
Balk, JL; Christenson, WR; Kohashi, M; Piper, WN; Sadler, EM; Tse, J1
Bernstein, M; Shivji, A1
Brodie, MJ; Goldberg, A; Kehoe, B; McGuire, G; Meissner, PN; Moore, MR; Yeung Laiwah, AC1
Bock, W; Bringmann, G; Fels, G; Franck, B; Grubenbecher, F; Marsmann, M; Pietschmann, R; Schäpers, K; Spiegel, U; Steinkamp, R; Ufer, G; Wegner, C1
Urata, G1
Hardin, SH; Harris-Haller, LW; Hashimoto, Y; Murooka, Y; Roessner, CA; Sattler, I; Scott, AI; Stolowich, NJ; Yokubaitis, NT1
Bolt, EL; Roessner, CA; Scott, AI; Spencer, JB; Warren, MJ; Woodcock, SC1
Roessner, CA; Scott, AI; Spencer, JB; Stolowich, NJ1
Hungerer, C; Jahn, D; Troup, B1
Elder, GH; Roberts, AG1
Ando, M; Hanioka, N; Jinno, H; Nishimura, T; Onodera, S1
Kafala, B; Sasarman, A1
Hederstedt, L; Johansson, P1
Majumdar, D; Ndivo, V; Xu, K1
Buchenau, B; Heinemann, IU; Jahn, D; Kahnt, J; Thauer, RK1
Arch, DD; Bergeron, M; Franklin, MR; Hathaway, L; Kushner, JP; Phillips, JD1
Dülcks, T; Kemken, D; Layer, G; Müller, J; Parmar, V; Schiebel, HM; Storbeck, S; Walther, J; Warren, MJ1
Arnold, S; Bali, S; Brindley, AA; Ferguson, SJ; Warren, MJ; Zajicek, RS1
Heinz, DW; Klink, BU; Krausze, J; Layer, G; Saha, S; Storbeck, S1
Agarwal, AK; Chen, K; Clark, AM; Huang, Z; Li, W; Li, Y; Pan, X; Phillips, JD; Xu, T; Zhang, J1
Bali, S; Ferguson, SJ; Palmer, DJ; Schroeder, S; Warren, MJ1
Bulusu, G; Bung, N; Pradhan, M; Srinivasan, H1
Haufschildt, K; Kühner, M; Layer, G; Neumann, A; Storbeck, S; Streif, J1
Chen, M; Funamizu, T; Ishimori, K; Tanaka, Y; Uchida, T1
Deery, E; Lawrence, AD; Scott, AF; Warren, MJ1
Cao, K; Gao, Z; Li, J; Li, S; Liu, H; Shao, Y; Sun, F; Wang, A; Xiong, P; Yang, S1

Reviews

5 review(s) available for uroporphyrinogen iii and heme

ArticleYear
Enzymatic formation and cellular regulation of heme synthesis.
    Seminars in hematology, 1977, Volume: 14, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coenzyme A; Coproporphyrinogens; Enzyme Induction; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrins; Uroporphyrinogens

1977
Hepatic porphyrias. Current concepts.
    Postgraduate medicine, 1977, Volume: 62, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Coproporphyrinogens; Female; Genetic Diseases, Inborn; Heme; Humans; Liver Diseases; Male; Nervous System Diseases; Porphobilinogen; Porphyrias; Uroporphyrinogens

1977
Hemes, chlorophylls, and related compounds: biosynthesis and metabolic regulation.
    Advances in enzymology and related areas of molecular biology, 1978, Volume: 46

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Bacteria; Chlorophyll; Fungi; Heme; Hemin; Humans; Lead Poisoning; Liver; Methods; Oxygen; Plants; Porphyrias; Porphyrins; Protein Biosynthesis; Protoporphyrins; Uroporphyrinogens

1978
[The chemistry of porphyrins and their precursors on the heme biosynthetic chain].
    Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53, Issue:6

    Topics: Aminolevulinic Acid; Heme; Humans; Porphobilinogen; Porphyrins; Uroporphyrinogens

1995
[Unusual pathways and environmentally regulated genes of bacterial heme biosynthesis].
    Die Naturwissenschaften, 1996, Volume: 83, Issue:9

    Topics: Aminolevulinic Acid; Animals; Archaea; Bacteria; Gene Expression Regulation, Bacterial; Heme; Hydroxymethylbilane Synthase; Mammals; Plants; Pyrroles; Saccharomyces cerevisiae; Tetrapyrroles; Uroporphyrinogens

1996

Other Studies

29 other study(ies) available for uroporphyrinogen iii and heme

ArticleYear
The discovery of nature's biosynthetic pathways.
    Experientia, 1978, Jan-15, Volume: 34, Issue:1

    Topics: Chlorophyll; Desulfovibrio; Heme; Porphyrinogens; Propionibacterium; Protoporphyrins; Uroporphyrinogens; Vitamin B 12

1978
The biosynthesis of haem in congenital (erythropoietic) porphyria.
    The International journal of biochemistry, 1978, Volume: 9, Issue:12

    Topics: 5-Aminolevulinate Synthetase; Adult; Child; Child, Preschool; Coproporphyrinogens; Erythrocytes; Erythropoiesis; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphobilinogen; Porphyrias; Porphyrins; Uroporphyrinogens

1978
Evidence for pteridine regulation of lead-mediated inhibition of uroporphyrinogen and heme formation in rat bone marrow.
    Toxicology and applied pharmacology, 1992, Volume: 113, Issue:1

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Bone Marrow; Drug Synergism; Heme; Heme Oxygenase (Decyclizing); Injections, Intraperitoneal; Lead; Male; Microsomes; Nitrous Oxide; Protoporphyrins; Pteridines; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; Uroporphyrinogen III Synthetase; Uroporphyrinogens

1992
Pteridine modulation of lead inhibition of uroporphyrinogen synthesis in erythroid precursor cells.
    Toxicology letters, 1990, Volume: 51, Issue:1

    Topics: Animals; Cell Line; Dialysis; Folic Acid; Hematopoietic Stem Cells; Heme; Lead; Leukemia, Erythroblastic, Acute; Mice; Porphyrinogens; Pteridines; Uroporphyrinogens

1990
Porphyria. Basic science aspects.
    Dermatologic clinics, 1986, Volume: 4, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Bone Marrow; Complement Activation; Heme; Humans; Lipid Metabolism; Liver; Models, Biological; Porphyrias; Porphyrinogens; Porphyrins; Skin Diseases; Uroporphyrinogens

1986
Inhibition of the biosynthesis of uroporphyrinogen and heme in rat liver during obstructive jaundice produced by bile duct ligation.
    Archives of biochemistry and biophysics, 1986, Volume: 246, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cholestasis, Extrahepatic; Common Bile Duct; Cytochrome P-450 Enzyme System; Heme; Hydroxymethylbilane Synthase; Hyperbilirubinemia; Liver; Male; Microsomes, Liver; Porphyrinogens; Rats; Rats, Inbred Strains; Uroporphyrinogens

1986
Stimulation of 5-aminolevulinic acid metabolism by uroporphyrinogen I in rat liver homogenate.
    Clinical biochemistry, 1985, Volume: 18, Issue:2

    Topics: Aminolevulinic Acid; Animals; Cell-Free System; Heme; In Vitro Techniques; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrinogens; Porphyrins; Rats; Rats, Inbred Strains; Uroporphyrinogens

1985
Carbamazepine and haem biosynthesis.
    Lancet (London, England), 1983, Oct-08, Volume: 2, Issue:8354

    Topics: Carbamazepine; Child; Heme; Humans; Porphobilinogen Synthase; Uroporphyrinogens

1983
Chemistry of porphyrin biosynthesis: results and applications.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Animals; Carbon Radioisotopes; Ducks; Heme; Molecular Conformation; Porphobilinogen; Porphyrins; Radioisotope Dilution Technique; Structure-Activity Relationship; Tritium; Uroporphyrinogens

1980
Cloning, sequencing, and expression of the uroporphyrinogen III methyltransferase cobA gene of Propionibacterium freudenreichii (shermanii).
    Journal of bacteriology, 1995, Volume: 177, Issue:6

    Topics: Amino Acid Sequence; Base Sequence; Carbon Isotopes; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Heme; Magnetic Resonance Spectroscopy; Methyltransferases; Molecular Sequence Data; Propionibacterium; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Uroporphyrinogens; Uroporphyrins; Vitamin B 12

1995
Gene dissection demonstrates that the Escherichia coli cysG gene encodes a multifunctional protein.
    The Biochemical journal, 1994, Sep-15, Volume: 302 ( Pt 3)

    Topics: Amino Acid Sequence; Base Sequence; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Genes, Bacterial; Heme; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Sequence Data; NADP; Recombinant Proteins; S-Adenosylmethionine; Uroporphyrinogens; Uroporphyrins

1994
The Escherichia coli cysG gene encodes the multifunctional protein, siroheme synthase.
    FEBS letters, 1993, Nov-29, Volume: 335, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Escherichia coli; Genes, Bacterial; Heme; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Molecular Sequence Data; Multienzyme Complexes; NAD; Sequence Homology, Amino Acid; Uroporphyrinogens

1993
Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes.
    Methods in enzymology, 1997, Volume: 281

    Topics: Coproporphyrinogens; Enzyme Inhibitors; Erythrocytes; Heme; Humans; Kinetics; Metals; Molecular Weight; Uroporphyrinogen Decarboxylase; Uroporphyrinogens; Uroporphyrins

1997
Irgasan DP 300 (5-chloro-2-(2,4-dichlorophenoxy)-phenol) induces cytochrome P450s and inhibits haem biosynthesis in rat hepatocytes cultured on Matrigel.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:7

    Topics: Aminolevulinic Acid; Animals; Anti-Infective Agents, Local; Carbanilides; Cells, Cultured; Chromatography, High Pressure Liquid; Collagen; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Combinations; Enzyme Induction; Extracellular Matrix; Heme; Laminin; Liver; Male; Proteoglycans; Rats; Rats, Wistar; Uroporphyrinogen III Synthetase; Uroporphyrinogens; Uroporphyrins

1997
Isolation of the Staphylococcus aureus hemCDBL gene cluster coding for early steps in heme biosynthesis.
    Gene, 1997, Oct-15, Volume: 199, Issue:1-2

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Escherichia coli Proteins; Genes, Bacterial; Genetic Complementation Test; Heme; Hydroxymethylbilane Synthase; Intramolecular Transferases; Molecular Sequence Data; Molecular Weight; Multigene Family; Open Reading Frames; Porphobilinogen Synthase; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus aureus; Uroporphyrinogen III Synthetase; Uroporphyrinogens

1997
Organization of genes for tetrapyrrole biosynthesis in gram--positive bacteria.
    Microbiology (Reading, England), 1999, Volume: 145 ( Pt 3)

    Topics: Amino Acid Sequence; Bacillaceae; Bacillus; Bacterial Proteins; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Gram-Positive Bacteria; Heme; Methyltransferases; Molecular Sequence Data; Multigene Family; Pyrroles; RNA, Transfer, Amino Acyl; Sequence Homology, Amino Acid; Tetrapyrroles; Uroporphyrinogens; Uroporphyrins

1999
Cloning and expression of Chlorobium vibrioforme uroporphyrinogen decarboxylase gene in a Salmonella heme auxotroph.
    Current microbiology, 2002, Volume: 45, Issue:6

    Topics: Chlorobi; Cloning, Molecular; Coproporphyrinogens; Culture Media; Heme; Salmonella; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

2002
Heme biosynthesis in Methanosarcina barkeri via a pathway involving two methylation reactions.
    Journal of bacteriology, 2006, Volume: 188, Issue:24

    Topics: Archaeal Proteins; Culture Media; Heme; Methanosarcina barkeri; Methionine; Methylation; Uroporphyrinogens; Uroporphyrins

2006
Longitudinal study of a mouse model of familial porphyria cutanea tarda.
    Cellular and molecular biology (Noisy-le-Grand, France), 2009, Jul-01, Volume: 55, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Genotype; Glutathione Transferase; Heme; Hemochromatosis Protein; Histocompatibility Antigens Class I; Liver; Longitudinal Studies; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Proteins; Porphyria Cutanea Tarda; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrinogens

2009
The Pseudomonas aeruginosa nirE gene encodes the S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase required for heme d(1) biosynthesis.
    The FEBS journal, 2009, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Bacterial Proteins; Genetic Complementation Test; Heme; Methyltransferases; Molecular Sequence Data; Protein Binding; Pseudomonas aeruginosa; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity; Uroporphyrinogens; Uroporphyrins

2009
d(1) haem biogenesis - assessing the roles of three nir gene products.
    The FEBS journal, 2009, Volume: 276, Issue:21

    Topics: Anion Transport Proteins; Bacteria; Cytochromes; Escherichia coli Proteins; Heme; Nitrite Reductases; Paracoccus pantotrophus; Uroporphyrinogens; Uroporphyrins

2009
Crystal structure of the heme d1 biosynthesis enzyme NirE in complex with its substrate reveals new insights into the catalytic mechanism of S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferases.
    The Journal of biological chemistry, 2011, Jul-29, Volume: 286, Issue:30

    Topics: Bacterial Proteins; Catalysis; Crystallography, X-Ray; Heme; Methyltransferases; Mutagenesis, Site-Directed; Mutation, Missense; Protein Structure, Tertiary; Pseudomonas aeruginosa; Uroporphyrinogens

2011
Sampangine inhibits heme biosynthesis in both yeast and human.
    Eukaryotic cell, 2011, Volume: 10, Issue:11

    Topics: Alkaloids; ATP-Dependent Proteases; Cell Line, Tumor; Cell Proliferation; Heme; Heterocyclic Compounds, 4 or More Rings; Humans; Jurkat Cells; Mitochondrial Proteins; Mitochondrial Proton-Translocating ATPases; Naphthyridines; Plant Extracts; Protoporphyrinogen Oxidase; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Uroporphyrinogen III Synthetase; Uroporphyrinogens

2011
Recent advances in the biosynthesis of modified tetrapyrroles: the discovery of an alternative pathway for the formation of heme and heme d 1.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:15

    Topics: Animals; Biosynthetic Pathways; Heme; Humans; Models, Molecular; Tetrapyrroles; Uroporphyrinogens

2014
Structural insights into E. coli porphobilinogen deaminase during synthesis and exit of 1-hydroxymethylbilane.
    PLoS computational biology, 2014, Volume: 10, Issue:3

    Topics: Catalysis; Catalytic Domain; Computational Biology; Diffusion; Escherichia coli; Heme; Hydroxymethylbilane Synthase; Molecular Conformation; Molecular Dynamics Simulation; Mutation; Pyrroles; Uroporphyrinogens

2014
The alternative route to heme in the methanogenic archaeon Methanosarcina barkeri.
    Archaea (Vancouver, B.C.), 2014, Volume: 2014

    Topics: Archaeal Proteins; Biosynthetic Pathways; Heme; Methanosarcina barkeri; Protein Multimerization; Uroporphyrinogens

2014
Heme Binding to Porphobilinogen Deaminase from Vibrio cholerae Decelerates the Formation of 1-Hydroxymethylbilane.
    ACS chemical biology, 2018, 03-16, Volume: 13, Issue:3

    Topics: Crystallography, X-Ray; Escherichia coli; Heme; Hydroxymethylbilane Synthase; Protein Binding; Spectrum Analysis, Raman; Uroporphyrinogens; Vibrio cholerae

2018
    Microbiology (Reading, England), 2021, Volume: 167, Issue:10

    Topics: Biosynthetic Pathways; Escherichia coli; Genetic Complementation Test; Heme; Hydroxymethylbilane Synthase; Mutation; Plasmodium falciparum; Protozoan Proteins; Uroporphyrinogen III Synthetase; Uroporphyrinogens

2021
Improved biosynthesis of heme in Bacillus subtilis through metabolic engineering assisted fed-batch fermentation.
    Microbial cell factories, 2023, May-18, Volume: 22, Issue:1

    Topics: Bacillus subtilis; Fermentation; Heme; Metabolic Engineering; Uroporphyrinogens

2023