Compounds > uridine triphosphate
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uridine triphosphate and psi 6130

uridine triphosphate has been researched along with psi 6130 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T1
Ali, S; Cammack, N; Jiang, WR; Klumpp, K; Lara-Jaime, T; Leveque, V; Ma, H; Masjedizadeh, M; Robledo, N; Smith, DB; Symons, J1
Bao, H; Furman, PA; Micolochick Steuer, HM; Murakami, E; Nachman, T; Niu, C; Otto, MJ; Sofia, MA; Wang, P; Whitaker, T1

Other Studies

3 other study(ies) available for uridine triphosphate and psi 6130

ArticleYear
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication

2007
Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.
    The Journal of biological chemistry, 2007, Oct-12, Volume: 282, Issue:41

    Topics: Antiviral Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxycytidine; DNA-Directed RNA Polymerases; Hepacivirus; Hepatocytes; Humans; Inhibitory Concentration 50; Models, Biological; Models, Chemical; Phosphates; Phosphorylation; RNA-Dependent RNA Polymerase; Virus Replication

2007
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Hepacivirus; Humans; Microbial Sensitivity Tests; Phosphorylation; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Uridine Triphosphate

2008