Page last updated: 2024-08-17

uridine triphosphate and deoxycytidine

uridine triphosphate has been researched along with deoxycytidine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (33.33)	18.2507
2000's	9 (60.00)	29.6817
2010's	1 (6.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T	1
Hertel, L; Reynolds, KK; Shewach, DS	1
Eriksson, S; Kierdaszuk, B; Krawiec, K; Munch-Petersen, B; Shugar, D	1
Peters, G; Pinedo, HM; van Haperen, VW; Veerman, G; Vermorken, JB	1
Hahn, TM; Hughes, TL; Reynolds, KK; Shewach, DS	1
Awad, R; Björk, I; Eriksson, S; Turk, B; Usova, EV	1
Bergman, AM; Jensen, PB; Munch-Petersen, B; Peters, GJ; Pinedo, HM; Sehested, M; Smid, K; Veerman, G; Voorn, DA	1
Cinatl, J; Doerr, HW; Gröschel, B; Höver, G; Kaufmann, A; Loves, WJ; Noordhuis, P; Peters, GJ	1
Parker, WB; Secrist, JA; Shaddix, SC; Someya, H; Tiwari, KN	1
Cass, CE; Eriksson, S; Mani, RS; Usova, EV	2
Bao, H; Furman, PA; Micolochick Steuer, HM; Murakami, E; Nachman, T; Niu, C; Otto, MJ; Sofia, MA; Wang, P; Whitaker, T	1
Iams, TA; McKee, EE; Morris, GW; Slepchenko, KG	1
Saada, A	1
Beijnen, JH; Derissen, EJB; Huitema, ADR; Rosing, H; Schellens, JHM	1

Trials

1 trial(s) available for uridine triphosphate and deoxycytidine

Article	Year
Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2',2'-difluorodeoxyuridine and their nucleotides. British journal of clinical pharmacology, 2018, Volume: 84, Issue:6 Topics: Activation, Metabolic; Antimetabolites, Antineoplastic; Breast Neoplasms; Cytidine Triphosphate; Deamination; Deoxycytidine; Female; Floxuridine; Gemcitabine; Humans; Leukocytes, Mononuclear; Phosphorylation; Uridine Triphosphate	2018

Article

Year

Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2',2'-difluorodeoxyuridine and their nucleotides.

British journal of clinical pharmacology, 2018, Volume: 84, Issue:6

Topics: Activation, Metabolic; Antimetabolites, Antineoplastic; Breast Neoplasms; Cytidine Triphosphate; Deamination; Deoxycytidine; Female; Floxuridine; Gemcitabine; Humans; Leukocytes, Mononuclear; Phosphorylation; Uridine Triphosphate

2018

Other Studies

14 other study(ies) available for uridine triphosphate and deoxycytidine

Article	Year
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication	2007
Nucleotide specificity of human deoxycytidine kinase. Molecular pharmacology, 1992, Volume: 42, Issue:3 Topics: Adenosine Triphosphate; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Guanosine Triphosphate; Humans; Kinetics; Nucleotides; Phosphates; Phosphorylation; Substrate Specificity; T-Lymphocytes; Uridine Triphosphate	1992
Nucleoside triphosphate donors for nucleoside kinases: donor properties of UTP with human deoxycytidine kinase. Biochemical and biophysical research communications, 1995, Nov-02, Volume: 216, Issue:1 Topics: Adenosine Triphosphate; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Humans; Kinetics; Leukemia; Phosphorus Radioisotopes; Radioisotope Dilution Technique; Spleen; Substrate Specificity; Tritium; Uridine Triphosphate	1995
Regulation of phosphorylation of deoxycytidine and 2',2'-difluorodeoxycytidine (gemcitabine); effects of cytidine 5'-triphosphate and uridine 5'-triphosphate in relation to chemosensitivity for 2',2'-difluorodeoxycytidine. Biochemical pharmacology, 1996, Apr-12, Volume: 51, Issue:7 Topics: Cytidine Deaminase; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Kinase; Enzyme Inhibitors; Female; Gemcitabine; Humans; Kinetics; Nucleoside Deaminases; Ovarian Neoplasms; Phosphorylation; Tumor Cells, Cultured; Uridine Triphosphate	1996
Kinetic analysis of human deoxycytidine kinase with the true phosphate donor uridine triphosphate. Biochemistry, 1997, Jun-17, Volume: 36, Issue:24 Topics: Adenosine Triphosphate; Binding, Competitive; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxycytidine Kinase; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Phosphates; Phosphorylation; Uridine Triphosphate	1997
A pre-steady-state kinetic analysis of substrate binding to human recombinant deoxycytidine kinase: a model for nucleoside kinase action. Biochemistry, 1999, Jun-29, Volume: 38, Issue:26 Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Binding Sites; Deoxycytidine; Deoxycytidine Kinase; Enzyme Activation; Genetic Vectors; Humans; Kinetics; Models, Chemical; Recombinant Fusion Proteins; Substrate Specificity; Uridine Triphosphate	1999
Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines. Biochemical pharmacology, 2001, Jun-01, Volume: 61, Issue:11 Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Carcinoma, Small Cell; Cell Survival; Cytarabine; Cytidine Deaminase; Daunorubicin; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Guanosine Triphosphate; Humans; Lung Neoplasms; Nucleoside Deaminases; Teniposide; Thymidine Kinase; Tumor Cells, Cultured; Uridine Triphosphate	2001
3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells. Biochemical pharmacology, 2002, Jul-15, Volume: 64, Issue:2 Topics: Adenosine Triphosphate; Anti-HIV Agents; Blotting, Western; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Microbial; Gemcitabine; HIV-1; Humans; RNA, Messenger; T-Lymphocytes; Thymidine Kinase; Uridine Triphosphate; Zidovudine	2002
Phosphorylation of 4'-thio-beta-D-arabinofuranosylcytosine and its analogs by human deoxycytidine kinase. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3 Topics: Adenosine Triphosphate; Arabinonucleosides; Cell Division; Cell Extracts; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Humans; Phosphoric Monoester Hydrolases; Phosphorylation; Tumor Cells, Cultured; Uridine Triphosphate	2003
Hydrodynamic and spectroscopic studies of substrate binding to human recombinant deoxycytidine kinase. Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:2 Topics: Adenosine Triphosphate; Binding Sites; Chromatography, Gel; Circular Dichroism; Deoxycytidine; Deoxycytidine Kinase; Dimerization; DNA, Complementary; Humans; Ligands; Protein Structure, Secondary; Recombinant Proteins; Spectrophotometry, Ultraviolet; Substrate Specificity; Ultracentrifugation; Uridine Triphosphate	2003
Fluorescence studies of substrate binding to human recombinant deoxycytidine kinase. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Deoxycytidine; Deoxycytidine Kinase; Gemcitabine; Humans; Kinetics; Ligands; Microscopy, Fluorescence; Neoplasms; Phosphates; Phosphorylation; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Substrate Specificity; Uridine Triphosphate	2004
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Hepacivirus; Humans; Microbial Sensitivity Tests; Phosphorylation; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Uridine Triphosphate	2008
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity. The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; In Vitro Techniques; Male; Perfusion; Phosphorylation; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine	2009
Fishing in the (deoxyribonucleotide) pool. The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3 Topics: Animals; Antimetabolites; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; Humans; Mitochondria; Mitochondrial Diseases; Models, Biological; Phosphorylation; Pyrimidine Nucleotides; Rats; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine	2009