Page last updated: 2024-08-17

uridine monophosphate and uracil

uridine monophosphate has been researched along with uracil in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199024 (32.43)18.7374
1990's14 (18.92)18.2507
2000's10 (13.51)29.6817
2010's24 (32.43)24.3611
2020's2 (2.70)2.80

Authors

AuthorsStudies
Hartmann, MD; Heim, C; Hernandez Alvarez, B; Maiwald, S1
Chevallier, MR; Jund, R; Lacroute, F1
Moner, JG; Plunkett, W1
Currier, TC; Wolk, CP1
Shambaugh, GE1
Dalke, P; Magill, JM1
Blocker, R; Roth, JS1
Ferris, JP; Joshi, PC1
Blasi, F; Bruni, CB; Colantuoni, V; Cortese, R; Sbordone, L1
Fast, R; Sköld, O1
Chen, ZH; Chu, E; Chu, MY; Chu, SH; Darnowski, JW; Pan, BC1
Karnahl, U; Wasternack, C1
Bourd, GI; Garibyan, AG; Nudler, AA1
de Montigny, J; Jund, R; Kern, L; Lacroute, F1
Engelbrecht, C; Yngner, T1
Jyssum, S1
Fujimoto, S; Kaneko, M; Kikugawa, M; Mizota, C; Tamaki, N1
Bronk, JR; Hastewell, JG1
Kelln, RA; Neuhard, J; Stauning, L1
Basappa, SC; Murthy, VS; Vishwanath, P1
Gero, AM; O'Sullivan, WJ; Scott, HV1
Blackmore, JA; Parry, TE1
Chirikjian, JG; Davis, FF; Matsushita, T; Remsen, JF1
Lindahl, T1
Deeble, DJ; von Sonntag, C1
Davis, CH; Putnam, MD; Thwaites, WM1
McIvor, RS; Plagemann, PG; Wohlhueter, RM1
Ketley, K; O'Sullivan, WJ1
Görner, H; Gurzadyan, GG1
Clark, MG; Colquhoun, EQ; Dora, KA; Rattigan, S; Richards, SM1
Jones, ME; Traut, TW1
Bârzu, O; Cristea, I; Gilles, AM; Hilden, I; Jensen, KF; Namane, A; Palibroda, N; Sarfati, RS; Ughetto-Monfrin, J1
D'Enfert, C; Debeaupuis, JP; Delit, A; Diaquin, M; Huerre, M; Latge, JP; Wuscher, N1
Beigelman, L; Deng, L; Gershon, PD; Karpeisky, A; Matulic-Adamic, J1
Clifford, AJ; Ho, YK1
Kanavarioti, A1
Miller, SL; Stribling, R1
Kozlov, IA; Orgel, LE1
Cygler, M; Larocque, R; Matte, A; Sauvé, V; Schrag, JD; Sivaraman, J; Stura, EA1
Ashihara, H; Katahira, R1
Sievers, A; Wolfenden, R1
HANDSCHUMACHER, RE; PASTERNAK, CA1
West, TP1
Carmeli, S; Reisner, M; Sukenik, A; Werman, M1
Castro, P; Kantardjieff, KA; Kim, CY; Lekin, T; Rho, BS; Rupp, B; Segelke, BW; Terwilliger, TC; Vasquez, C; Warfel, NM1
Arsène-Ploetze, F; Bringel, F; Kammerer, B; Martinussen, J; Nicoloff, H1
Hoskins, J; Scott Butler, J1
Iams, TA; McKee, EE; Morris, GW; Slepchenko, KG1
Saada, A1
Guillaumont, S; Maître, P; Ortiz, D; Salpin, JY; Tortajada, J1
Garavaglia, M; Landini, P; Rossi, E1
Angelico, R; Ceglie, A; Introna, B; Losito, I; Palmisano, F1
Bao, L; Harris, SD; Hu, C; Jin, C; Li, S; Liu, H; Sun, X; Zhu, J1
Hosios, AM; Rabinowitz, JD; Reaves, ML; Xu, YF; Young, BD1
Fairlamb, AH; Ong, HB; Patterson, S; Sienkiewicz, N; Wyllie, S1
Ray, K1
Borgia, G; Buonomo, AR; Gentile, I; Zappulo, E1
Cornberg, M; Höner zu Siederdissen, C1
Halász, T; Horváth, G; Hunyady, B; Makara, M1
Bailly, F; Pradat, P; Virlogeux, V; Zoulim, F1
Bastian, ND; Griffin, PM; Zhang, S1
Buti, M; Esteban, R; Riveiro-Barciela, M1
Berry, K; Beste, LA; Chang, MF; Green, PK; Ioannou, GN; Lowy, E; Su, F; Tsui, JI1
Bryce, CL; Chidi, AP; Donohue, JM; Fine, MJ; Landsittel, DP; Myaskovsky, L; Rogal, SS; Smith, KJ; Switzer, GE; Tsung, A1
De Weggheleire, A; Dorlo, TP; Francque, S; Lynen, L; Meessen, B; Newton, PN; Pouget, C; Ravinetto, R; Sokkab, A; Tabernero, P1
Aichelburg, MC; Bucsics, T; Ferenci, P; Grabmeier-Pfistershammer, K; Mandorfer, M; Peck-Radosavljevic, M; Reiberger, T; Scheiner, B; Schwabl, P; Steiner, S; Trauner, M1
Albillos, A; Ampuero, J; Arenas, J; Bañares, R; Calleja, JL; Crespo, J; Diago, M; Fernandez, I; García-Eliz, M; García-Samaniego, J; Gea, F; Jorquera, F; Lens, S; Llaneras, J; Llerena, S; Mariño, Z; Morillas, RM; Muñoz, R; Navascues, CA; Pascasio, JM; Perelló, C; Rincón, D; Rodriguez, CF; Ruiz-Antorán, B; Sacristán, B; Serra, MA; Simon, MA; Torras, X; Turnes, J1
Alston, S; Di Bisceglie, AM; Evon, DM; Fried, MW; Golin, CE; Lim, JK; Lok, AS; Nelson, DR; Reau, N; Reddy, KR; Reeve, B; Sarkar, S; Sterling, RK; Stewart, P1
Bou-Nader, C; Cornu, D; Fogeron, T; Fontecave, M; Guerineau, V; Hamdane, D1
Cerban, R; Ester, C; Gheorghe, C; Gheorghe, L; Iacob, R; Iacob, S; Pietrareanu, C; Popescu, I1
Adamek, B; Baka-Ćwierz, B; Belica-Wdowik, T; Berak, H; Białkowska-Warzecha, J; Buczyńska, I; Citko, J; Czauż-Andrzejuk, A; Deroń, Z; Dobracki, W; Dybowska, D; Flisiak, R; Garlicki, A; Gietka, A; Halota, W; Horban, A; Janczewska, E; Jaroszewicz, J; Laurans, Ł; Lorenc, B; Mazur, W; Piekarska, A; Simon, K; Sitko, M; Socha, Ł; Tomasiewicz, K; Tronina, O; Tudrujek-Zdunek, M; Wawrzynowicz-Syczewska, M; Zarębska-Michaluk, D1
Brister, MM; Crespo-Hernández, CE1
Berg, T; Boeker, KHW; Buggisch, P; C-Registry, GH; Günther, R; Hinrichsen, H; Klinker, H; Manns, MP; Mauss, S; Müller, T; Serfert, Y; Wiegand, J; Zeuzem, S1
Gupta, M; Levine, SR; Spitale, RC1

Reviews

6 review(s) available for uridine monophosphate and uracil

ArticleYear
Pyrimidine biosynthesis.
    The American journal of clinical nutrition, 1979, Volume: 32, Issue:6

    Topics: Animals; Aspartate Carbamoyltransferase; Bicarbonates; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Dihydroorotase; Dihydroorotate Oxidase; Glutamine; Humans; Lesch-Nyhan Syndrome; Lymphocytes; Models, Biological; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Purines; Pyrimidines; Uracil; Uridine Kinase; Uridine Monophosphate; Uridine Phosphorylase

1979
Uracil metabolism--UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs.
    Progress in nucleic acid research and molecular biology, 1996, Volume: 53

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; beta-Alanine; Biological Evolution; DNA, Complementary; Humans; Molecular Sequence Data; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Peptide Synthases; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate

1996
Interferon-free therapies for chronic hepatitis C: toward a hepatitis C virus-free world?
    Expert review of anti-infective therapy, 2014, Volume: 12, Issue:7

    Topics: 2-Naphthylamine; Amides; Anilides; Antiviral Agents; Benzofurans; Carbamates; Clinical Trials as Topic; Cyclopropanes; Disease Eradication; Drug Combinations; Hepacivirus; Hepatitis C; Humans; Imidazoles; Isoquinolines; Lactams, Macrocyclic; Macrocyclic Compounds; Proline; Pyrrolidines; Quinoxalines; Ribavirin; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine

2014
[All-oral, interferon-free therapies for patients with chronic genotype 1 hepatitis C virus infection].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:47

    Topics: 2-Naphthylamine; Administration, Oral; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Drug Combinations; Fluorenes; Genotype; Germany; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Proline; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine

2014
[New era in the treatment of chronic hepatitis C - novel direct acting antivirals].
    Orvosi hetilap, 2015, May-24, Volume: 156, Issue:21

    Topics: 2-Naphthylamine; Administration, Oral; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Interferons; Isoquinolines; Lactams, Macrocyclic; Liver Neoplasms; Macrocyclic Compounds; Nucleic Acid Synthesis Inhibitors; Proline; Protease Inhibitors; Pyrrolidines; Simeprevir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine; Viral Load; Viral Nonstructural Proteins; Virus Replication

2015
Management of direct-acting antiviral agent failures.
    Journal of hepatology, 2015, Volume: 63, Issue:6

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Clinical Trials as Topic; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Interferons; Lactams, Macrocyclic; Macrocyclic Compounds; Proline; Protease Inhibitors; Pyrrolidines; Ribavirin; Simeprevir; Sofosbuvir; Sulfonamides; Treatment Failure; Uracil; Uridine Monophosphate; Valine

2015

Other Studies

68 other study(ies) available for uridine monophosphate and uracil

ArticleYear
Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay.
    ACS medicinal chemistry letters, 2021, Jan-14, Volume: 12, Issue:1

    Topics:

2021
Uracil transport in Saccharomyces cerevisiae.
    The Journal of membrane biology, 1977, Sep-14, Volume: 36, Issue:2-3

    Topics: Azides; Biological Transport, Active; Cell-Free System; Dinitrophenols; Hydrogen-Ion Concentration; Mutation; N-Glycosyl Hydrolases; Pentosyltransferases; Pyrimidines; Saccharomyces cerevisiae; Uracil; Uridine Kinase; Uridine Monophosphate

1977
UMP pyrophosphorylase of Tetrahymena pyriformis. Partial purification and properties.
    Archives of biochemistry and biophysics, 1978, Apr-15, Volume: 187, Issue:1

    Topics: Animals; Enzyme Induction; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Pyrimidines; Temperature; Tetrahymena pyriformis; Uracil; Uridine Monophosphate

1978
Regulation of uridylic acid biosynthesis in the cyanobacterium Anabaena variabilis.
    Journal of bacteriology, 1978, Volume: 136, Issue:2

    Topics: Aspartate Carbamoyltransferase; Cyanobacteria; Dihydroorotase; Dihydroorotate Oxidase; Nucleotides; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Uracil; Uracil Nucleotides; Uridine Monophosphate

1978
Specificity of uracil uptake in Neurospora crassa.
    Journal of bacteriology, 1979, Volume: 139, Issue:1

    Topics: Biological Transport, Active; Chemical Phenomena; Chemistry; Kinetics; Neurospora; Neurospora crassa; Pentosyltransferases; Structure-Activity Relationship; Uracil; Uridine Monophosphate

1979
The reduction of uridine 5'-diphosphate and uridine 5'-triphosphate in some transplantable rat hepatomas.
    Cancer research, 1977, Volume: 37, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleosides; Deoxyribonucleotides; Hydrolysis; Hydroxyurea; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Oxidation-Reduction; Rats; Ribonucleotide Reductases; Uracil; Uracil Nucleotides; Uridine; Uridine Diphosphate Glucose; Uridine Monophosphate

1977
Chemical evolution from hydrogen cyanide: photochemical decarboxylation of orotic acid and orotate derivatives.
    Science (New York, N.Y.), 1978, Jul-28, Volume: 201, Issue:4353

    Topics: Decarboxylation; Hydrogen Cyanide; Orotic Acid; Photochemistry; Ribonucleotides; Uracil; Uridine; Uridine Monophosphate

1978
Biochemical and regulatory properties of Escherichia coli K-12 hisT mutants.
    Journal of bacteriology, 1977, Volume: 130, Issue:1

    Topics: Adenine; Anticodon; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes, Regulator; Histidine; Hydro-Lyases; Isoleucine; Mutation; Operon; Pentosyltransferases; Pseudouridine; Uracil; Uridine Monophosphate

1977
Biochemical mechanism of uracil uptake regulation in Escherichia coli B. Allosteric effects on uracil phosphoribosyltransferase under stringent conditions.
    The Journal of biological chemistry, 1977, Nov-10, Volume: 252, Issue:21

    Topics: Adenine; Allosteric Regulation; Biological Transport, Active; Chloramphenicol; Coliphages; Escherichia coli; Guanosine Tetraphosphate; Guanosine Triphosphate; Kinetics; Pentosyltransferases; Species Specificity; Uracil; Uridine Monophosphate

1977
Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7

    Topics: Antimetabolites, Antineoplastic; Cell Division; Cell Line; Colonic Neoplasms; Deoxyuridine; DNA Replication; Drug Synergism; Floxuridine; Humans; Kinetics; Recombinant Proteins; Thymidylate Synthase; Uracil; Uridine Monophosphate

1992
Half-life of cytoplasmic rRNA and tRNA, of plastid rRNA and of uridine nucleotides in heterotrophically and photoorganotrophically grown cells of Euglena gracilis and its apoplastic mutant W3BUL.
    The International journal of biochemistry, 1992, Volume: 24, Issue:3

    Topics: Animals; Cytoplasm; Euglena gracilis; Half-Life; RNA, Ribosomal; RNA, Transfer; Uracil; Uracil Nucleotides; Uridine Monophosphate; Uridine Triphosphate

1992
The derepression of enzymes of de novo pyrimidine biosynthesis pathway in Brevibacterium ammoniagenes producing uridine-5-monophosphate and uracil.
    FEMS microbiology letters, 1991, Aug-15, Volume: 66, Issue:3

    Topics: Brevibacterium; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Mutation; Pyrimidines; Uracil; Uridine Monophosphate

1991
The FUR1 gene of Saccharomyces cerevisiae: cloning, structure and expression of wild-type and mutant alleles.
    Gene, 1990, Apr-16, Volume: 88, Issue:2

    Topics: Alleles; Amino Acid Sequence; Base Sequence; Chromosome Deletion; Cloning, Molecular; DNA Mutational Analysis; DNA, Recombinant; Fluorouracil; Genes, Fungal; Molecular Sequence Data; Orotate Phosphoribosyltransferase; Pentosyltransferases; Plasmids; Saccharomyces cerevisiae; Uracil; Uridine Monophosphate

1990
Metabolism of uridine and determination of liver ribonucleic acid synthesis in developing and adult mice.
    The International journal of biochemistry, 1985, Volume: 17, Issue:4

    Topics: Aging; Alanine; Animals; beta-Alanine; Liver; Male; Mice; Orotic Acid; RNA; Tritium; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate

1985
Pyrimidine 5'-nucleosidase in Neisseria meningitidis. An enzyme specific for uridine 5'-monophosphate.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1989, Volume: 97, Issue:4

    Topics: N-Glycosyl Hydrolases; Neisseria meningitidis; Ribosemonophosphates; Streptomyces; Uracil; Uridine Monophosphate

1989
Inhibitory effect of 6-azauracil on beta-alanine metabolism in rat.
    Journal of nutritional science and vitaminology, 1989, Volume: 35, Issue:5

    Topics: Alanine; Amidohydrolases; Animals; Dihydrouracil Dehydrogenase (NAD+); Liver; Male; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Rats, Inbred Strains; Uracil; Uridine Monophosphate

1989
The transport and metabolism of the uridine mononucleotides by rat jejunum in vitro.
    The Journal of physiology, 1989, Volume: 408

    Topics: Animals; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Time Factors; Uracil; Uracil Nucleotides; Uridine; Uridine Monophosphate

1989
Isolation and characterization of pyrimidine mutants of Salmonella typhimurium altered in expression of pyrC, pyrD, and pyrE.
    Canadian journal of microbiology, 1985, Volume: 31, Issue:11

    Topics: Alleles; beta-Galactosidase; Cytidine; DNA Transposable Elements; DNA, Recombinant; Gene Expression Regulation; Genes, Bacterial; Genetic Linkage; Lac Operon; Mutation; Pyrimidines; Salmonella typhimurium; Transcription, Genetic; Uracil; Uracil Nucleotides; Uridine Monophosphate

1985
Mechanism of counteraction of aflatoxin toxicity by thymine and folic acid in Bacillus megaterium.
    Folia microbiologica, 1986, Volume: 31, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Aminopterin; Aspartic Acid; Bacillus megaterium; DNA, Bacterial; Drug Synergism; Folic Acid; Orotic Acid; Thymine; Uracil; Uridine Monophosphate

1986
In vitro inhibition of Plasmodium falciparum by pyrazofurin, an inhibitor of pyrimidine biosynthesis de novo.
    Molecular and biochemical parasitology, 1986, Volume: 18, Issue:1

    Topics: Amides; Chloroquine; Culture Media; Erythrocytes; Humans; Malaria; Male; Middle Aged; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Plasmodium falciparum; Pyrazoles; Ribonucleosides; Ribose; Uracil; Uridine; Uridine Monophosphate

1986
Serum 'uracil plus uridine' levels in normal subjects and their possible significance.
    Journal of clinical pathology, 1974, Volume: 27, Issue:10

    Topics: Age Factors; Bacteriological Techniques; Base Sequence; Biological Assay; Culture Media; Female; Humans; Kinetics; Lactococcus lactis; Male; Mutagens; Sex Factors; Uracil; Uridine; Uridine Monophosphate

1974
Enzymatic synthesis of deoxypseudouridylic acid and a study of certain of its properties.
    Biochimica et biophysica acta, 1972, Nov-09, Volume: 281, Issue:4

    Topics: Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Deoxyribonucleosides; Deoxyribonucleotides; DNA, Bacterial; Electrophoresis, Paper; Escherichia coli; L Cells; Pentosephosphates; Pentosyltransferases; Pseudouridine; Rhizobium; Spectrophotometry, Ultraviolet; Uracil; Uracil Nucleotides; Uridine Monophosphate

1972
An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:9

    Topics: Binding Sites; Chromatography, Paper; Cytosine; Deoxycytidine Monophosphate; Deoxyuridine; DNA; DNA, Single-Stranded; Escherichia coli; Glucosidases; Magnesium; RNA; Thymine; Uracil; Uracil Nucleotides; Uridine Monophosphate

1974
Gamma-radiolysis of poly(U) in aqueous solution. The role of primary sugar and base radicals in the release of undamaged uracil.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1984, Volume: 46, Issue:3

    Topics: Cobalt Radioisotopes; Gamma Rays; Poly U; Radiochemistry; Solutions; Tetranitromethane; Uracil; Uridine Monophosphate; Water

1984
Metabolism of dihydrouracil in Rhodosporidium toruloides.
    Journal of bacteriology, 1984, Volume: 158, Issue:1

    Topics: Basidiomycota; Carbon Dioxide; Mutation; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Uracil; Uridine Monophosphate; Ustilaginales

1984
Uridine phosphorylase from Acholeplasma laidlawii: purification and kinetic properties.
    Journal of bacteriology, 1983, Volume: 156, Issue:1

    Topics: Acholeplasma laidlawii; Kinetics; Molecular Weight; Pentosyltransferases; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate; Uridine Phosphorylase

1983
Biosynthesis of uridine monophosphate in Plasmodium berghei.
    Annals of tropical medicine and parasitology, 1980, Volume: 74, Issue:2

    Topics: Animals; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxonic Acid; Plasmodium berghei; Potassium; Uracil; Uracil Nucleotides; Uridine Monophosphate

1980
Damage to uracil- and adenine-containing bases, nucleosides, nucleotides and polynucleotides: quantum yields on irradiation at 193 and 254 nm.
    Photochemistry and photobiology, 1994, Volume: 60, Issue:4

    Topics: Adenine; Adenosine; Adenosine Monophosphate; DNA Damage; Dose-Response Relationship, Radiation; Lasers; Polydeoxyribonucleotides; Polyribonucleotides; Quantum Theory; Structure-Activity Relationship; Ultraviolet Rays; Uracil; Uridine; Uridine Monophosphate

1994
Role of extracellular UTP in the release of uracil from vasoconstricted hindlimb.
    The American journal of physiology, 1993, Volume: 264, Issue:1 Pt 2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Blood Pressure; Extracellular Space; Hindlimb; Male; Muscle, Smooth, Vascular; Nucleotides; Oxygen Consumption; Rats; Rats, Wistar; Uracil; Uridine Monophosphate; Uridine Triphosphate; Vasoconstriction

1993
Chemienzymatic synthesis of uridine nucleotides labeled with [15N] and [13C].
    Analytical biochemistry, 1995, Dec-10, Volume: 232, Issue:2

    Topics: Adenosine Triphosphate; Bacterial Proteins; Carbon Isotopes; Enzymes; Fungal Proteins; Glucose; Isotope Labeling; Magnetic Resonance Spectroscopy; NADP; Nitrogen Isotopes; Phosphorylation; Recombinant Proteins; Ribulosephosphates; Uracil; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

1995
Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus.
    Infection and immunity, 1996, Volume: 64, Issue:10

    Topics: Animals; Aspergillus fumigatus; Female; Mice; Uracil; Uridine; Uridine Monophosphate; Virulence

1996
Specific recognition of an rU2-N15-rU motif by VP55, the vaccinia virus poly(A) polymerase catalytic subunit.
    The Journal of biological chemistry, 1997, Dec-12, Volume: 272, Issue:50

    Topics: Binding Sites; Models, Chemical; Polynucleotide Adenylyltransferase; Protein Conformation; Ribose; RNA; RNA, Messenger; RNA, Viral; Uracil; Uridine Monophosphate; Vaccinia virus

1997
Development and survival of Drosophila melanogaster fed a diet containing pyrimidine analogs.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1997, Volume: 118, Issue:1

    Topics: Animals; Bromouracil; Cytosine; Diet; Drosophila melanogaster; Female; Larva; Male; Orotic Acid; Pupa; Pyrimidines; Thymine; Uracil; Uridine Monophosphate

1997
Preference for internucleotide linkages as a function of the number of constituents in a mixture.
    Journal of molecular evolution, 1998, Volume: 46, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cytidine Monophosphate; Cytosine; Dimerization; Evolution, Chemical; Guanine; Guanosine Monophosphate; Hydrolysis; Nucleotides; Solutions; Uracil; Uridine Monophosphate

1998
Attempted nonenzymatic template-directed oligomerizations on a polyadenylic acid template: implications for the nature of the first genetic material.
    Journal of molecular evolution, 1991, Volume: 32

    Topics: Evolution, Molecular; Hydrogen-Ion Concentration; Oligonucleotides; Origin of Life; Phosphorylation; Poly A; Purines; Pyrimidines; Quinazolines; Ribonucleotides; Temperature; Templates, Genetic; Uracil; Uridine Monophosphate; Xanthine

1991
Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues.
    Helvetica chimica acta, 1999, Volume: 82, Issue:11

    Topics: 2-Aminopurine; Adenine; Adenosine; Adenosine Monophosphate; Base Pairing; Cytidine Monophosphate; Cytosine; DNA Primers; Evolution, Chemical; Evolution, Molecular; Exobiology; Guanine; Inosine Monophosphate; RNA; Templates, Genetic; Uracil; Uridine Monophosphate

1999
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
    Nature structural biology, 2002, Volume: 9, Issue:5

    Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Intramolecular Transferases; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; RNA, Ribosomal, 16S; Sequence Alignment; Substrate Specificity; Uracil; Uridine Monophosphate

2002
Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.
    Planta, 2002, Volume: 215, Issue:5

    Topics: Carbon Radioisotopes; Culture Techniques; Cytidine; Cytidine Deaminase; Cytosine; Cytosine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleosides; Enzymes; Multienzyme Complexes; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Phosphotransferases; Plant Stems; Pyrimidine Nucleosides; Pyrimidine Phosphorylases; Pyrimidines; Pyrimidinones; Solanum tuberosum; Thymidine; Thymidine Kinase; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate; Uridine Phosphorylase

2002
Equilibrium of formation of the 6-carbanion of UMP, a potential intermediate in the action of OMP decarboxylase.
    Journal of the American Chemical Society, 2002, Nov-27, Volume: 124, Issue:47

    Topics: Deuterium; Hot Temperature; Kinetics; Orotidine-5'-Phosphate Decarboxylase; Uracil; Uridine Monophosphate

2002
Inhibition of orotidylic acid decarboxylase, a primary site of carcinostasis by 6-azauracil.
    Biochimica et biophysica acta, 1958, Volume: 30, Issue:2

    Topics: Antineoplastic Agents; Carboxy-Lyases; Lyases; Uracil; Uridine Monophosphate

1958
Regulation of pyrimidine nucleotide formation in Pseudomonas reptilivora.
    Letters in applied microbiology, 2004, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Aspartic Acid; Dihydroorotase; Dihydroorotate Dehydrogenase; Diphosphates; Enzyme Inhibitors; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases Acting on CH-CH Group Donors; Pseudomonas; Pyrimidine Nucleotides; Uracil; Uridine Monophosphate

2004
The cyanobacterial toxin cylindrospermopsin inhibits pyrimidine nucleotide synthesis and alters cholesterol distribution in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 82, Issue:2

    Topics: Alkaloids; Anemia; Anemia, Hypochromic; Animals; Bacterial Toxins; Cholesterol; Cyanobacteria; Cyanobacteria Toxins; Enzyme Inhibitors; Erythrocytes; Hematocrit; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; Multienzyme Complexes; Organ Size; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Pyrimidine Nucleotides; Tissue Distribution; Uracil; Uridine Monophosphate

2004
Structure of pyrR (Rv1379) from Mycobacterium tuberculosis: a persistence gene and protein drug target.
    Acta crystallographica. Section D, Biological crystallography, 2005, Volume: 61, Issue:Pt 4

    Topics: Amino Acid Sequence; Antitubercular Agents; Bacterial Proteins; Binding Sites; Crystallization; Crystallography, X-Ray; Genes, Bacterial; Genes, Regulator; Ligands; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Protein Structure, Quaternary; Repressor Proteins; Sequence Alignment; Uracil; Uridine Monophosphate

2005
Uracil salvage pathway in Lactobacillus plantarum: Transcription and genetic studies.
    Journal of bacteriology, 2006, Volume: 188, Issue:13

    Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactobacillus plantarum; Multigene Family; Operon; Pentosyltransferases; Pyrimidines; Repressor Proteins; Transcription, Genetic; Uracil; Uridine Monophosphate

2006
Evidence for distinct DNA- and RNA-based mechanisms of 5-fluorouracil cytotoxicity in Saccharomyces cerevisiae.
    Yeast (Chichester, England), 2007, Volume: 24, Issue:10

    Topics: Antimetabolites, Antineoplastic; DNA; DNA Repair; Fluorouracil; RNA; Saccharomyces cerevisiae; Uracil; Uridine Monophosphate

2007
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
    The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; In Vitro Techniques; Male; Perfusion; Phosphorylation; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine

2009
Fishing in the (deoxyribonucleotide) pool.
    The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3

    Topics: Animals; Antimetabolites; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; Humans; Mitochondria; Mitochondrial Diseases; Models, Biological; Phosphorylation; Pyrimidine Nucleotides; Rats; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine

2009
Direct evidence for tautomerization of the uracil moiety within the Pb2+/uridine-5'-monophosphate complex: a combined tandem mass spectrometry and IRMPD study.
    Inorganic chemistry, 2011, Aug-15, Volume: 50, Issue:16

    Topics: Coordination Complexes; Gases; Ions; Lead; Models, Molecular; Molecular Structure; Phase Transition; Solutions; Spectrophotometry, Infrared; Tandem Mass Spectrometry; Uracil; Uridine Monophosphate

2011
The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Biofilms; Biosynthetic Pathways; Cellulose; Escherichia coli; Escherichia coli Proteins; Extracellular Matrix; Gene Expression Regulation, Bacterial; Pyrimidine Nucleotides; Uracil; Uridine Monophosphate

2012
Cytosine to uracil conversion through hydrolytic deamination of cytidine monophosphate hydroxy-alkylated on the amino group: a liquid chromatography--electrospray ionization--mass spectrometry investigation.
    Journal of mass spectrometry : JMS, 2012, Volume: 47, Issue:10

    Topics: Alkylation; Chromatography, High Pressure Liquid; Cytidine Monophosphate; Cytosine; Models, Molecular; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Uracil; Uridine Monophosphate

2012
PyrG is required for maintaining stable cellular uracil level and normal sporulation pattern under excess uracil stress in Aspergillus nidulans.
    Science China. Life sciences, 2013, Volume: 56, Issue:5

    Topics: Aspergillus nidulans; Chromatography, High Pressure Liquid; Fungal Proteins; Gene Expression Profiling; Gene Expression Regulation, Fungal; Microscopy, Electron, Scanning; Mutation; Orotidine-5'-Phosphate Decarboxylase; Spores, Fungal; Uracil; Uridine Monophosphate

2013
Pyrimidine homeostasis is accomplished by directed overflow metabolism.
    Nature, 2013, Aug-08, Volume: 500, Issue:7461

    Topics: Carbon; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Enzymologic; Genes, Suppressor; Homeostasis; Nucleoside-Phosphate Kinase; Pyrimidines; Transferases; Uracil; Uridine Monophosphate

2013
Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
    Molecular microbiology, 2013, Volume: 90, Issue:2

    Topics: Amides; Animals; Biological Transport; Cell Line; Deoxyuridine; Fluorouracil; Gene Knockout Techniques; Mice; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Transfection; Trypanocidal Agents; Trypanosoma brucei brucei; Uracil; Uridine; Uridine Monophosphate; Virulence

2013
Viral hepatitis: new hepatitis C therapies-a medical pick and mix.
    Nature reviews. Gastroenterology & hepatology, 2014, Volume: 11, Issue:6

    Topics: Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Macrocyclic Compounds; Male; Ribavirin; Ritonavir; Sulfonamides; Uracil; Uridine Monophosphate

2014
Antiviral Therapy in Patients with Hepatitis C Virus-Induced Cirrhosis.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Interferon-alpha; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Proline; Protease Inhibitors; Pyrrolidines; Ribavirin; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine

2015
Cost-effectiveness of sofosbuvir-based treatments for chronic hepatitis C in the US.
    BMC gastroenterology, 2015, Aug-05, Volume: 15

    Topics: Antiviral Agents; Benzimidazoles; Cost-Benefit Analysis; Drug Combinations; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Macrocyclic Compounds; Male; Markov Chains; Middle Aged; Polyethylene Glycols; Quality-Adjusted Life Years; Ribavirin; Ritonavir; Simeprevir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate

2015
Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Health Care System.
    Gastroenterology, 2016, Volume: 151, Issue:3

    Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C; Humans; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Proline; Retrospective Studies; Ritonavir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; United States; United States Department of Veterans Affairs; Uracil; Uridine Monophosphate; Valine

2016
Economic and Public Health Impacts of Policies Restricting Access to Hepatitis C Treatment for Medicaid Patients.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2016, Volume: 19, Issue:4

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cost-Benefit Analysis; Cyclopropanes; Drug Combinations; Female; Fluorenes; Health Services Accessibility; Hepacivirus; Hepatitis C; HIV Protease Inhibitors; Humans; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Markov Chains; Medicaid; Middle Aged; Proline; Ritonavir; Severity of Illness Index; Sofosbuvir; Sulfonamides; United States; Uracil; Uridine Monophosphate; Valine

2016
Predictable threats to public health through delaying universal access to innovative medicines for hepatitis C: a pharmaceutical standpoint.
    Tropical medicine & international health : TM & IH, 2016, Volume: 21, Issue:12

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Drug Industry; Drug Therapy, Combination; Fees, Pharmaceutical; Fluorenes; Health Services Accessibility; Hepatitis C, Chronic; Humans; Imidazoles; Lactams, Macrocyclic; Macrocyclic Compounds; Proline; Public Health; Pyrrolidines; Quality Assurance, Health Care; Quality Control; Ritonavir; Simeprevir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine

2016
Progress in eradication of HCV in HIV positive patients with significant liver fibrosis in Vienna.
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:15-16

    Topics: 2-Naphthylamine; Adult; AIDS-Related Opportunistic Infections; Anilides; Anti-HIV Agents; Antiviral Agents; Austria; Benzimidazoles; Carbamates; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Hepatitis C, Chronic; HIV Seropositivity; Humans; Lactams, Macrocyclic; Liver; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Proline; Retrospective Studies; Ritonavir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine

2017
Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort.
    Journal of hepatology, 2017, Volume: 66, Issue:6

    Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Genotype; Glomerular Filtration Rate; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Neoplasms; Macrocyclic Compounds; Male; Middle Aged; Neoplasm Recurrence, Local; Proline; Retrospective Studies; Ribavirin; Ritonavir; Sofosbuvir; Spain; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Uridine Monophosphate; Valine; Young Adult

2017
Patient engagement and study design of PROP UP: A multi-site patient-centered prospective observational study of patients undergoing hepatitis C treatment.
    Contemporary clinical trials, 2017, Volume: 57

    Topics: Adult; Antiviral Agents; Benzimidazoles; Benzofurans; Carbamates; Drug Combinations; Female; Fluorenes; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Macrocyclic Compounds; Male; Patient Participation; Patient-Centered Care; Prospective Studies; Pyrrolidines; Quinoxalines; Ritonavir; Sofosbuvir; Sulfonamides; Treatment Outcome; Uracil; Uridine Monophosphate; Valine

2017
Enzyme Activation with a Synthetic Catalytic Co-enzyme Intermediate: Nucleotide Methylation by Flavoenzymes.
    Angewandte Chemie (International ed. in English), 2017, 10-02, Volume: 56, Issue:41

    Topics: Bacillus subtilis; Enzyme Activation; Flavins; Methylation; Models, Molecular; RNA, Transfer; Thermotoga maritima; Thymidylate Synthase; tRNA Methyltransferases; Uracil; Uridine Monophosphate

2017
100% sustained virological response and fibrosis improvement in real-life use of direct acting antivirals in genotype-1b recurrent hepatitis C following liver transplantation.
    Journal of gastrointestinal and liver diseases : JGLD, 2018, Volume: 27, Issue:2

    Topics: 2-Naphthylamine; Adult; Aged; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Cirrhosis; Liver Transplantation; Macrocyclic Compounds; Male; Middle Aged; Proline; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Uracil; Uridine Monophosphate; Valine

2018
The efficacy of paritaprevir/ritonavir/ombitasvir+dasabuvir and ledipasvir/sofosbuvir is comparable in patients who failed interferon-based treatment with first generation protease inhibitors - a multicenter cohort study.
    BMC infectious diseases, 2018, Nov-16, Volume: 18, Issue:1

    Topics: 2-Naphthylamine; Adult; Aged; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cohort Studies; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Poland; Proline; Protease Inhibitors; Ritonavir; Sofosbuvir; Sulfonamides; Treatment Outcome; Uracil; Uridine Monophosphate; Valine; Young Adult

2018
Excited-State Dynamics in the RNA Nucleotide Uridine 5'-Monophosphate Investigated Using Femtosecond Broadband Transient Absorption Spectroscopy.
    The journal of physical chemistry letters, 2019, May-02, Volume: 10, Issue:9

    Topics: Electrons; Models, Molecular; Molecular Conformation; Photochemical Processes; Quantum Theory; RNA; Spectrophotometry; Thermodynamics; Ultraviolet Rays; Uracil; Uridine Monophosphate; Vibration; Water

2019
Hepatitis C therapy with direct antiviral agents in patients with advanced chronic kidney disease: real-world experience of the German Hepatitis C-Registry (Deutsches Hepatitis C-Register).
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:11

    Topics: 2-Naphthylamine; Acute Disease; Adult; Aged; Anemia; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Female; Fluorenes; Germany; Glomerular Filtration Rate; Hepatitis C, Chronic; Humans; Hypertension; Imidazoles; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Pleural Effusion; Proline; Pyrrolidines; Registries; Renal Insufficiency, Chronic; Ribavirin; Ritonavir; RNA, Viral; Severity of Illness Index; Simeprevir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Uridine Monophosphate; Valine

2019
Probing Nascent RNA with Metabolic Incorporation of Modified Nucleosides.
    Accounts of chemical research, 2022, 09-20, Volume: 55, Issue:18

    Topics: Nucleosides; RNA; Transferases; Uracil; Uridine Monophosphate

2022