Page last updated: 2024-08-17

uridine monophosphate and ledipasvir

uridine monophosphate has been researched along with ledipasvir in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's33 (84.62)24.3611
2020's6 (15.38)2.80

Authors

AuthorsStudies
Ding, X; Hyland, RH; Lawitz, E; McHutchison, JG; Membreno, FE; Mo, H; Pang, PS; Poordad, FF; Symonds, WT1
Ding, X; Gane, EJ; Hyland, RH; McHutchison, JG; Pang, PS; Stedman, CA; Subramanian, GM; Svarovskaia, E; Symonds, WT1
An, D; Bernstein, DE; Chojkier, M; Di Bisceglie, AM; Fried, MW; Ghalib, R; Gordon, SC; Herring, R; Hyland, RH; Kowdley, KV; Lawitz, E; McHutchison, JG; Muir, AJ; Pang, PS; Pockros, PJ; Pound, D; Reddy, KR; Rossaro, L; Rustgi, V; Ryan, M; Schiff, E; Shiffman, ML; Subramanian, GM; Svarovskaia, E; Symonds, WT1
Hoofnagle, JH; Sherker, AH1
Afdhal, N; Arora, S; Di Bisceglie, AM; Dvory-Sobol, H; Ghalib, R; Gitlin, N; Gordon, SC; Herring, R; Kwo, P; Lalezari, J; Lawitz, E; McHutchison, JG; Muir, AJ; Nahass, R; Nelson, DR; Pang, PS; Pockros, PJ; Reddy, KR; Schiff, E; Subramanian, GM; Sulkowski, M; Symonds, WT; Yang, JC; Younes, ZH; Zhu, Y1
Afdhal, N; Agarwal, K; Bräu, N; Buggisch, P; Buti, M; Chojkier, M; Ding, X; Foster, GR; Gitlin, N; Jacobson, IM; Kwo, P; Mangia, A; Marcellin, P; McHutchison, JG; Mo, H; Muir, AJ; Pang, PS; Puoti, M; Romero-Gomez, M; Subramanian, GM; Symonds, WT; Yang, JC; Zarski, JP; Zeuzem, S1
Feld, JJ1
Sofia, MJ1
German, P; Mathias, A; Moorehead, L; Pang, P; Vimal, M1
Delaney, W; Dvory-Sobol, H; Lawitz, EJ; Mabery, E; McHutchison, J; Miller, MD; Mo, H; Skurnac, T; Svarovskaia, ES; Voitenleitner, C1
Carroll, J1
Fauci, AS; Kohli, A; Kottilil, S; Marti, MM; Masur, H; McHutchison, JG; Meissner, EG; Nelson, A; Osinusi, A; Pang, PS; Silk, R; Subramanian, GM; Townsend, K; Zhang, X1
Firpi, RJ; Hilgenfeldt, E1
Cornberg, M; Höner zu Siederdissen, C1
Chan, J; Mohammad, RA; Smith, MA1
Nelson, DR; Peter, J1
Foster, GR1
Abbott, S; Barrett, LL; Bon, D; Chavez, J; Diaz, G; Egerson, D; Fauci, AS; Gross, C; Herrmann, E; Jolley, TA; Kapoor, R; Kleiner, DE; Kohli, A; Kotb, C; Kottilil, S; Kwan, R; Marti, MM; Masur, H; McHutchison, J; Meissner, EG; Nelson, A; Osinusi, A; Pang, PS; Petersen, T; Polis, MA; Proschan, M; Sidharthan, S; Silk, R; Sims, Z; Sneller, M; Spurlin, E; Subramanian, GM; Symonds, WT; Talwani, R; Teferi, G; Townsend, K; Wood, BJ1
Kumari, R; Nguyen, MH1
Beckerman, R; Jiang, Y; Smith, NJ; Stepanova, M; Younossi, ZM1
Floreani, A1
Chhatwal, J; Dunn, MA; Kanwal, F; Roberts, MS1
Betular, J; Enomoto, H; Gao, B; Garrison, K; Genda, T; Ide, T; Ikeda, F; Ishizaki, A; Izumi, N; Knox, SJ; Korenaga, M; McHutchison, JG; Mizokami, M; Mo, H; Mochizuki, H; Nakane, K; Nirei, K; Nishigaki, Y; Omata, M; Omote, M; Pang, PS; Sakamoto, N; Symonds, WT; Takehara, T; Toda, N; Toyoda, H; Ueno, Y; Umemura, T; Yanase, M; Yatsuhashi, H; Yokosuka, O1
Halász, T; Horváth, G; Hunyady, B; Makara, M1
Kmietowicz, Z1
Baden, RP; Bräu, N; Colson, AE; Cooper, C; Dieterich, D; Dvory-Sobol, H; Gane, E; German, P; Jayaweera, D; Luetkemeyer, A; Marks, K; McHutchison, JG; Morales-Ramirez, JO; Naggie, S; Ni, L; Pang, PS; Ruane, P; Saag, M; Santana-Bagur, J; Sax, PE; Stamm, LM; Stedman, CA; Sulkowski, M; Tebas, P; Towner, WJ; Wong, DK; Workowski, K; Yang, JC1
Kohli, A; Kottilil, S; Masur, H; Meissner, EG; Osinusi, A; Remaley, AT; Sampson, M; Sidharthan, S; Tang, L; Townsend, K1
Abo-Talib, NF; El-Ghobashy, MR; Tammam, MH1
Goda, Y; Hakamatsuka, T; Hosoe, J; Kamakura, H; Maruyama, T; Masada, S; Tokumoto, H; Tsujimoto, T; Uchiyama, N1
Guedj, J; Kohli, A; Kottilil, S; Nguyen, THT; Perelson, AS; Uprichard, SL1
Brown, AN; Drusano, GL; Li, E; Liu, L; Neely, MN; Rodriquez, JL; Schuster, L; Wang, GP; Yamada, W; Zhao, L1
El-Shorbagy, HI; Elbrashy, AM; Elsebaei, F; Hammad, SF1
Amarsanaa, J; Baatarkhuu, O; Enkhtuya, D; Enkhzaya, S; Hsu, SJ; Ivshinkhorol, D; Jargalsaikhan, B; Kao, JH; Khosbayar, T; Lin, YY; Naranzul, N; Tsai, CH; Tseng, TC; Wang, TS1
Abd-Elsalam, S; Abdellatif, RS; Abo-Amer, YE; Elbedewy, TA; Elsebaey, MA; Fouad, A; Mostafa, SM; Youssef, M1
Abbassi, MM; Ebeid, FS; El-Baraky, IA; El-Sayed, MH; Hassany, M; Sabry, NA1
Bair, MJ; Chang, CC; Chang, TS; Chen, CH; Chen, CT; Chen, CY; Chen, GY; Cheng, PN; Chong, LW; Chuang, WL; Dai, CY; Hsieh, TY; Hsiung, CK; Hu, JT; Huang, CF; Huang, CS; Huang, JF; Huang, YH; Hung, CH; Kao, CN; Kao, JH; Kuo, HT; Lee, MH; Lee, PL; Lee, TH; Lin, CL; Lin, CW; Lin, CY; Lin, HC; Liu, CH; Liu, CJ; Lo, CC; Mo, LR; Peng, CY; Su, WW; Tai, CM; Tsai, PC; Tsai, WL; Tseng, KC; Wang, CC; Wang, SJ; Wu, WC; Yang, CC; Yang, SS; Yeh, ML; Yu, ML1
AlBayati, SM; Faraj, OA1
Abd-Aal, MS; Abdel-Hafez, AS; Abdel-Hamid, TM; Abdel-Rahman, RZ; Abdelsalam, MFA; Elaatar, MB; Elgohary, MA; Elkady, AO; Elnagar, MT; Elnagdy, TR; Elsaied, MA; Emam, ME; Fatoh, AR; Hamada, MM; Hasan, EM; Helmy, S; Ibrahim, AA; Lotfy, HH; Mubark, MA; Nawar, OM; Sakr, MA; Seadawy, MG; Selem, MA; Shehata, MM; Zaki, AI1

Reviews

7 review(s) available for uridine monophosphate and ledipasvir

ArticleYear
Interferon-free strategies with a nucleoside/nucleotide analogue.
    Seminars in liver disease, 2014, Volume: 34, Issue:1

    Topics: Animals; Antiviral Agents; Benzimidazoles; Drug Design; Drug Resistance, Viral; Fluorenes; Hepacivirus; Hepatitis C; Humans; Interferons; Molecular Targeted Therapy; Nucleosides; Nucleotides; Protease Inhibitors; Sofosbuvir; Treatment Outcome; Uridine Monophosphate; Viral Nonstructural Proteins

2014
Hepatitis C management in post-transplant patients.
    Minerva gastroenterologica e dietologica, 2015, Volume: 61, Issue:1

    Topics: Antiviral Agents; Benzimidazoles; Carbamates; Drug Therapy, Combination; Fluorenes; Hepatitis C; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Liver Transplantation; Oligopeptides; Polyethylene Glycols; Proline; Pyrrolidines; Recombinant Proteins; Recurrence; Ribavirin; Risk Factors; Simeprevir; Sofosbuvir; Sulfonamides; Treatment Outcome; Uridine Monophosphate; Valine; Viral Load

2015
[All-oral, interferon-free therapies for patients with chronic genotype 1 hepatitis C virus infection].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:47

    Topics: 2-Naphthylamine; Administration, Oral; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Drug Combinations; Fluorenes; Genotype; Germany; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Proline; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine

2014
Ledipasvir-sofosbuvir: interferon-/ribavirin-free regimen for chronic hepatitis C virus infection.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:3

    Topics: Adult; Animals; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Fluorenes; Genotype; Headache; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Nausea; Ribavirin; Sofosbuvir; Uridine Monophosphate

2015
Optimal interferon-free therapy in treatment-experienced chronic hepatitis C patients.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35 Suppl 1

    Topics: Antiviral Agents; Benzimidazoles; Carbamates; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Precision Medicine; Pyrrolidines; Sofosbuvir; Uridine Monophosphate; Valine

2015
Fixed-dose combination of sofosbuvir and ledipasvir for the treatment of chronic hepatitis C genotype 1.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:5

    Topics: Antiviral Agents; Benzimidazoles; Clinical Trials as Topic; Drug Combinations; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Liver Cirrhosis; Meta-Analysis as Topic; Recurrence; Sofosbuvir; Uridine Monophosphate; Viral Nonstructural Proteins

2015
[New era in the treatment of chronic hepatitis C - novel direct acting antivirals].
    Orvosi hetilap, 2015, May-24, Volume: 156, Issue:21

    Topics: 2-Naphthylamine; Administration, Oral; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Interferons; Isoquinolines; Lactams, Macrocyclic; Liver Neoplasms; Macrocyclic Compounds; Nucleic Acid Synthesis Inhibitors; Proline; Protease Inhibitors; Pyrrolidines; Simeprevir; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine; Viral Load; Viral Nonstructural Proteins; Virus Replication

2015

Trials

13 trial(s) available for uridine monophosphate and ledipasvir

ArticleYear
Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial.
    Lancet (London, England), 2014, Feb-08, Volume: 383, Issue:9916

    Topics: Antiviral Agents; Benzimidazoles; Drug Administration Schedule; Drug Combinations; Female; Fluorenes; Genotype; Hepatitis C, Chronic; Humans; Male; Middle Aged; Protease Inhibitors; Ribavirin; RNA, Viral; Sofosbuvir; Treatment Outcome; Uridine Monophosphate; Viral Nonstructural Proteins

2014
Efficacy of nucleotide polymerase inhibitor sofosbuvir plus the NS5A inhibitor ledipasvir or the NS5B non-nucleoside inhibitor GS-9669 against HCV genotype 1 infection.
    Gastroenterology, 2014, Volume: 146, Issue:3

    Topics: Adult; Aged; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Enzyme Inhibitors; Fatigue; Female; Fluorenes; Furans; Genotype; Headache; Hepacivirus; Hepatitis C; Humans; Incidence; Male; Middle Aged; Nausea; Sofosbuvir; Thiophenes; Treatment Outcome; Uridine Monophosphate; Viral Nonstructural Proteins

2014
Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis.
    The New England journal of medicine, 2014, May-15, Volume: 370, Issue:20

    Topics: Adult; Aged; Antiviral Agents; Benzimidazoles; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Ribavirin; RNA, Viral; Sofosbuvir; Uridine Monophosphate; Viral Load; Young Adult

2014
Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.
    The New England journal of medicine, 2014, Apr-17, Volume: 370, Issue:16

    Topics: Adult; Aged; Antiviral Agents; Benzimidazoles; Drug Combinations; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Nucleotidyltransferases; RNA-Dependent RNA Polymerase; Sofosbuvir; Uridine Monophosphate; Viral Load; Viral Nonstructural Proteins

2014
Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection.
    The New England journal of medicine, 2014, May-15, Volume: 370, Issue:20

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Benzimidazoles; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Ribavirin; RNA, Viral; Sofosbuvir; Uridine Monophosphate; Viral Load; Young Adult

2014
Clinical and in vitro resistance to GS-9669, a thumb site II nonnucleoside inhibitor of the hepatitis C virus NS5B polymerase.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:11

    Topics: Adult; Antiviral Agents; Base Sequence; Benzimidazoles; Cell Line; Drug Resistance, Viral; Female; Fluorenes; Furans; Genetic Variation; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Binding; Quinolines; Ribavirin; Sequence Analysis, RNA; Sofosbuvir; Thiophenes; Treatment Outcome; Uridine Monophosphate; Viral Nonstructural Proteins

2014
Re-treatment of chronic hepatitis C virus genotype 1 infection after relapse: an open-label pilot study.
    Annals of internal medicine, 2014, Nov-04, Volume: 161, Issue:9

    Topics: Aged; Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Mutation; Recurrence; Ribavirin; RNA, Viral; Sofosbuvir; Uridine Monophosphate

2014
Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study.
    Lancet (London, England), 2015, Mar-21, Volume: 385, Issue:9973

    Topics: Aged; Antiviral Agents; Benzimidazoles; Cohort Studies; Drug Therapy, Combination; Female; Fluorenes; Furans; Hepacivirus; Hepatitis C, Chronic; Humans; Intention to Treat Analysis; Male; Middle Aged; Quinolines; Ribavirin; RNA, Viral; Sofosbuvir; Thiophenes; Treatment Outcome; Uridine Monophosphate; Viral Load

2015
Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiviral Agents; Asian People; Benzimidazoles; Drug-Related Side Effects and Adverse Reactions; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Japan; Male; Middle Aged; Ribavirin; Sofosbuvir; Time Factors; Treatment Outcome; Uridine Monophosphate; Young Adult

2015
Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1.
    The New England journal of medicine, 2015, Aug-20, Volume: 373, Issue:8

    Topics: Anti-Retroviral Agents; Antiviral Agents; Benzimidazoles; Drug Resistance, Viral; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Male; Middle Aged; RNA, Viral; Sofosbuvir; Uridine Monophosphate; Viral Load

2015
Interferon-Free Treatment of Hepatitis C Virus in HIV/Hepatitis C Virus-Coinfected Subjects Results in Increased Serum Low-Density Lipoprotein Concentration.
    AIDS research and human retroviruses, 2016, Volume: 32, Issue:5

    Topics: Antiviral Agents; Benzimidazoles; Cardiovascular Diseases; Cholesterol, LDL; Coinfection; Drug Therapy, Combination; Dyslipidemias; Female; Fluorenes; Furans; Hepacivirus; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Male; Middle Aged; Prospective Studies; Quinolines; Ribavirin; Sofosbuvir; Thiophenes; Uridine Monophosphate

2016
The paradox of highly effective sofosbuvir-based combination therapy despite slow viral decline: can we still rely on viral kinetics?
    Scientific reports, 2017, 08-31, Volume: 7, Issue:1

    Topics: Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Female; Fluorenes; Furans; Hepacivirus; Hepatitis C, Chronic; Humans; Kinetics; Male; Models, Theoretical; Quinolines; Sofosbuvir; Sustained Virologic Response; Thiophenes; Treatment Outcome; Uridine Monophosphate; Viral Load

2017
Efficacy of Sofosbuvir plus Ledipasvir in Egyptian patients with COVID-19 compared to standard treatment: a randomized controlled trial.
    Journal of medicine and life, 2022, Volume: 15, Issue:3

    Topics: Antiviral Agents; Benzimidazoles; COVID-19 Drug Treatment; Drug Therapy, Combination; Egypt; Fluorenes; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Ribavirin; SARS-CoV-2; Sofosbuvir; Treatment Outcome; Uridine Monophosphate

2022

Other Studies

19 other study(ies) available for uridine monophosphate and ledipasvir

ArticleYear
Therapy for hepatitis C--the costs of success.
    The New England journal of medicine, 2014, Apr-17, Volume: 370, Issue:16

    Topics: Antiviral Agents; Benzimidazoles; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Sofosbuvir; Uridine Monophosphate

2014
Beyond sofosbuvir: what opportunity exists for a better nucleoside/nucleotide to treat hepatitis C?
    Antiviral research, 2014, Volume: 107

    Topics: Antiviral Agents; Benzimidazoles; Drug Approval; Drug Discovery; Fluorenes; Hepatitis C, Chronic; Humans; Nucleosides; Nucleotides; Sofosbuvir; Uridine Monophosphate

2014
Lack of a clinically important pharmacokinetic interaction between sofosbuvir or ledipasvir and hormonal oral contraceptives norgestimate/ethinyl estradiol in HCV-uninfected female subjects.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:11

    Topics: Adult; Antiviral Agents; Area Under Curve; Benzimidazoles; Contraceptives, Oral, Combined; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Fluorenes; Half-Life; Hepacivirus; Humans; Norgestrel; Sofosbuvir; Uridine Monophosphate

2014
Sovaldi dilemma likely to get worse.
    Managed care (Langhorne, Pa.), 2014, Volume: 23, Issue:9

    Topics: Antiviral Agents; Benzimidazoles; Drug Combinations; Fluorenes; Hepatitis C; Humans; Prescription Fees; Sofosbuvir; United States; Uridine Monophosphate

2014
A combination of ledipasvir and sofosbuvir (Harvoni) for hepatitis C.
    The Medical letter on drugs and therapeutics, 2014, Nov-10, Volume: 56, Issue:1455

    Topics: Antiviral Agents; Benzimidazoles; Drug Approval; Drug Combinations; Drug Interactions; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Sofosbuvir; United States; United States Food and Drug Administration; Uridine Monophosphate

2014
Shorter treatments for hepatitis C: another step forward?
    Lancet (London, England), 2015, Mar-21, Volume: 385, Issue:9973

    Topics: Antiviral Agents; Benzimidazoles; Female; Fluorenes; Furans; Hepatitis C, Chronic; Humans; Male; Quinolines; Ribavirin; RNA, Viral; Sofosbuvir; Thiophenes; Uridine Monophosphate

2015
Ledipasvir/sofosbuvir regimens for chronic hepatitis C infection: Insights from a work productivity economic model from the United States.
    Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:5

    Topics: Antiviral Agents; Benzimidazoles; Costs and Cost Analysis; Efficiency; Fluorenes; Hepatitis C, Chronic; Humans; Models, Economic; Sofosbuvir; United States; Uridine Monophosphate

2015
Perspectives of fixed daily dose of sofosbuvir and ledipasvir for the treatment of chronic hepatitis C.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:6

    Topics: Antiviral Agents; Benzimidazoles; Coinfection; Drug Combinations; Fluorenes; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Randomized Controlled Trials as Topic; Recurrence; Sofosbuvir; Uridine Monophosphate

2015
Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States.
    Annals of internal medicine, 2015, Mar-17, Volume: 162, Issue:6

    Topics: Antiviral Agents; Benzimidazoles; Budgets; Cost-Benefit Analysis; Drug Costs; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insurance, Health, Reimbursement; Interferon-alpha; Markov Chains; Patient-Specific Modeling; Quality-Adjusted Life Years; Sofosbuvir; United States; Uridine Monophosphate

2015
Thousands of patients in England to get new hepatitis C drugs.
    BMJ (Clinical research ed.), 2015, Jun-12, Volume: 350

    Topics: Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; England; Fluorenes; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Lactams, Macrocyclic; Macrocyclic Compounds; Proline; Public Health; Pyrrolidines; Simeprevir; Sofosbuvir; Sulfonamides; Uridine Monophosphate; Valine

2015
Spectrophotometric Methods for Simultaneous Determination of Sofosbuvir and Ledipasvir (HARVONI Tablet): Comparative Study with Two Generic Products.
    Journal of AOAC International, 2017, Jul-01, Volume: 100, Issue:4

    Topics: Benzimidazoles; Drugs, Generic; Fluorenes; Sofosbuvir; Tablets; Therapeutic Equivalency; Uridine Monophosphate

2017
Chemical Analysis of Counterfeit Hepatitis C Drug Found in Japan.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, 10-01, Volume: 137, Issue:10

    Topics: Antiviral Agents; Benzimidazoles; Chromatography, Liquid; Counterfeit Drugs; Drugs, Chinese Herbal; Ephedrine; Fluorenes; Gas Chromatography-Mass Spectrometry; Glycyrrhizic Acid; Hepatitis C; Japan; Magnetic Resonance Spectroscopy; Mass Spectrometry; Sofosbuvir; Tablets; Uridine Monophosphate; Vitamins

2017
Sofosbuvir (SOF) Suppresses Ledipasvir (LDV)-resistant Mutants during SOF/LDV Combination Therapy against Genotype 1b Hepatitis C Virus (HCV).
    Scientific reports, 2017, 10-31, Volume: 7, Issue:1

    Topics: Antiviral Agents; Benzimidazoles; Cell Line; Combined Modality Therapy; Drug Interactions; Drug Resistance, Viral; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Models, Theoretical; Sofosbuvir; Uridine Monophosphate

2017
Earth-friendly spectrophotometric methods for simultaneous determination of ledipasvir and sofosbuvir: Application to average content and uniformity of dosage unit testing.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2018, Dec-05, Volume: 205

    Topics: Benzimidazoles; Fluorenes; Green Chemistry Technology; Limit of Detection; Linear Models; Reproducibility of Results; Sofosbuvir; Spectrophotometry; Tablets; Uridine Monophosphate

2018
Resistance-associated substitution and ledipasvir/sofosbuvir therapy in Mongolian chronic hepatitis C patients.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2020, Volume: 119, Issue:3

    Topics: Adult; Aged; Antiviral Agents; Benzimidazoles; Drug Resistance, Viral; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepatitis C, Chronic; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Mongolia; Sofosbuvir; Treatment Failure; Treatment Outcome; Uridine Monophosphate

2020
Sofosbuvir/Ledipasvir for Treatment of Chronic Hepatitis C Infection in Adult Patients with β- Thalassemia Major: A Real-Life Study.
    Endocrine, metabolic & immune disorders drug targets, 2022, Volume: 22, Issue:3

    Topics: Adult; Antiviral Agents; Benzimidazoles; beta-Thalassemia; Drug Therapy, Combination; Fluorenes; Genotype; Hepatitis C, Chronic; Humans; Retrospective Studies; Sofosbuvir; Thalassemia; Treatment Outcome; Uridine Monophosphate

2022
Beta-thalassemia major alters sofosbuvir/ledipasvir exposure in Hepatitis C virus infected adolescent patients.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Antiviral Agents; Benzimidazoles; beta-Thalassemia; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Pharmaceutical Preparations; Prospective Studies; Sofosbuvir; Treatment Outcome; Uridine Monophosphate

2021
Ledipasvir/sofosbuvir for HCV genotype 1, 2, 4-6 infection: Real-world evidence from a nationwide registry in Taiwan.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2022, Volume: 121, Issue:8

    Topics: Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Registries; Ribavirin; Sofosbuvir; Taiwan; Uridine Monophosphate

2022
Assessment of outcome for sample of Iraqi patients with chronic hepatitis C virus infection treated by Ledipasvir/sofosbuvir drug.
    JPMA. The Journal of the Pakistan Medical Association, 2021, Volume: 71(Suppl 8), Issue:12

    Topics: Antiviral Agents; Benzimidazoles; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Pharmaceutical Preparations; Prospective Studies; Ribavirin; Sofosbuvir; Treatment Outcome; Uridine Monophosphate

2021