Page last updated: 2024-08-17

uridine diphosphate and uridine triphosphate

uridine diphosphate has been researched along with uridine triphosphate in 150 studies

Research

Studies (150)

TimeframeStudies, this research(%)All Research%
pre-199012 (8.00)18.7374
1990's37 (24.67)18.2507
2000's72 (48.00)29.6817
2010's25 (16.67)24.3611
2020's4 (2.67)2.80

Authors

AuthorsStudies
Boeynaems, JM; Communi, D; Parmentier, M1
Dougherty, RW; Douglass, JG; Pendergast, W; Redick, CC; Rideout, JL; Shaver, SR; Sims, IF; Yerxa, BR1
Boyer, JL; Erlinge, D; Harden, TK; Jacobson, KA; Kim, HS; Maddileti, S; Malmsjö, M; Marquez, VE; Ravi, RG; Wihlborg, AK1
Jacobson, KA; Jarvis, MF; Williams, M1
El-Tayeb, A; Müller, CE; Qi, A1
Besada, P; Cappellacci, L; Carter, RL; Cosyn, L; de Castro, S; Franchetti, P; Grifantini, M; Harden, TK; Jacobson, KA; Ko, H; Petrelli, R; Van Calenbergh, S; Zhou, Y1
Camden, J; Eliahu, SE; Fischer, B; Gélinas, S; Lecka, J; Sévigny, J; Weisman, GA1
Fischer, B; Ginsburg-Shmuel, T; Haas, M; Kalid, O; Reiser, G; Schumann, M; Stern, N1
Balasubramanian, R; Barrett, MO; Berk, B; Burianek, LE; Costanzi, S; Harden, TK; Jacobson, KA; Ko, H; Maruoka, H; Melman, A; Tosh, DK1
El-Tayeb, A; Müller, CE; Nicholas, RA; Qi, A1
Camden, J; Fischer, B; Weisman, GA; Yelovitch, S1
Barrett, MO; Jacobson, KA; Kendall Harden, T; Martins, JC; Santhosh Kumar, T; Sinnaeve, D; Van Calenbergh, S; Van Poecke, S1
Arguin, G; Fischer, B; Gendron, FP; Ginsburg-Shmuel, T; Grbic, D; Haas, M; Nadel, Y; Reiser, G1
Gillard, M; Köse, M; Kostenis, E; Müller, CE; Ritter, K; Thiemke, K1
Arguin, G; Fischer, B; Gendron, FP; Pelletier, J; Sela, A; Senderowitz, H; Sévigny, J; Simhaev, L; Zelikman, V1
O'Brien, PJ1
Ingoglia, NA; Politis, MJ1
de Brito, R; Hallinan, T; Pohl, KR1
Cheung, CP; Suhadolnik, RJ1
Torrance, JD; Whittaker, D1
Carlberg, E; Engelbrecht, C; Lewan, L; Yngner, T1
Fischer, R; Nauck, M; Pavenstädt, H; Schlunck, G; Schollmeyer, P; Späth, M; Wanner, C1
Fukui, T; Kazuta, Y; Nakano, K; Omura, Y; Tagaya, M1
Heyworth, PG; Hutchinson, WL; Mowbray, J1
Hardebo, JE; Kåhrström, J; Owman, C; Salford, LG1
Cortes, P; Dumler, F; Levin, NW1
Epstein, J; Harkrader, RJ; Jackson, RC; Ross, DA1
Anukarahanonta, T; Holstege, A; Kattermann, R; Keppler, D; Koch, HK; Lesch, R; Yamamoto, M1
Aussedat, J; Grably, S; Rossi, A; Verdetti, J1
Dixon, SJ; Feldman, RD; Kaplan, AD; Reimer, WJ1
Enomoto, K; Furuya, K; Maeno, T; Oka, T; Yamagishi, S2
Fassy, F; Hervagault, JF1
Knop, RH; Miller, WM; Pederson, NV; Zanghi, JA1
Harden, TK; Lazarowski, ER1
Boehm, S; Huck, S; Illes, P1
Harden, K; Lazarowski, ER; Li, Q; Nicholas, RA; Watt, WC1
Barnard, EA; Bateson, AN; Burnstock, G; Henderson, D; King, BF; Simon, J; Wang, S; Webb, TE1
Bârzu, O; Cristea, I; Gilles, AM; Hilden, I; Jensen, KF; Namane, A; Palibroda, N; Sarfati, RS; Ughetto-Monfrin, J1
Boeynaems, JM; Motte, S; Swillens, S1
Cozzone, PJ; Fantini, J; Lutz, NW; Yahi, N1
Boucher, RC; Harden, TK; Lazarowski, ER; Paradiso, AM; Watt, WC1
Boyer, J; Harden, TK; Lazarowski, ER; Li, Q; Nicholas, RA; Watt, WC1
Braun, N; Zimmermann, H1
Fujio, T; Maruyama, A1
Boucher, RC; Harden, TK; Homolya, L; Lazarowski, ER1
Chen, BC; Lin, WW1
Anderson, CM; Parkinson, FE1
Enyeart, JA; Enyeart, JJ; Gomora, JC; Xu, L1
Chiba, S; Matsumoto, T; Nakane, T1
Carrey, EA; Zhu, LM1
Allen, EA; Khan, ZE; Ko, WH; Law, VW; Pediani, JD; Wilson, G; Wilson, SM1
Horio, Y; Iijima, T; Kondo, C; Kurachi, Y; Repunte, VP; Satoh, E; Yamada, M1
Boehm, S1
Langley, D; Pearce, B1
Hartley, SA; Kato, K; Kozlowski, RZ; Salter, KJ1
Järv, J; Kelve, M; Sak, K; Uri, A1
Barnard, EA; Brown, DA; Filippov, AK; Webb, TE1
Burnstock, G; Rubino, A; Ziabary, L1
Järv, J; Kelve, M; Sak, K; Samuel, K; Webb, TE1
Gallagher, M; Ko, WH; Rakhit, S; Remsbury, AL; Wilson, SM1
Bergdahl, A; Edvinsson, L; Erlinge, D; Hedner, T; Malmsjö, M; Möller, S; Sun, XY; Zhao, XH1
Collett, A; Inglis, SK; McAlroy, HL; Olver, RE; Wilson, SM1
Dijkema, C; Hugenholtz, J; Looijesteijn, E; Starrenburg, M1
Illes, P; Meyer, A; Nörenberg, W; Starke, K; von Kügelgen, I1
Dixon, CJ; Green, AK; Webb, TE; Woods, NM1
Badimon, JJ; Chesebro, JH; Fallon, JT; Fuster, V; Gallo, R; Helft, G; Osende, JI; Padurean, A; Rodriguez, OX; Worthley, SG; Zaman, AG1
Bagot, JC; Bouchie, JL; Carney, R; Chen, HC; Feener, EP; Wilden, PA1
Edvinsson, L; Erlinge, D; Harden, TK; Hou, M; Malmsjö, M; Pantev, E; Pendergast, W1
Boucher, RC; Harden, TK; Lazarowski, ER1
Adner, M; Edvinsson, L; Erlinge, D; Harden, TK; Malmsjö, M; Pendergast, W1
Dacey, RG; Dietrich, HH; Horiuchi, T; Tsugane, S1
Eliseev, VV; Rodionova, OM; Sapronov, NS1
Ekokoski, E; Simon, J; Törnquist, K; Webb, TE1
Kelve, M; Sak, K; Samuel, K; Webb, TE1
Boeynaems, JM; Bruyns, C; Duhant, X; Robaye, B; Suarez-Huerta, N; Wilkin, F1
Marcus, DC; Scofield, MA1
Nicholas, RA1
Chaulet, H; Desgranges, C; Dupuch, F; Ezan, G; Gadeau, AP; Loirand, G; Pacaud, P; Peiretti, F; Renault, MA1
Chiba, T; Lee, JH; Marcus, DC1
Insel, PA; Nicholas, RA; Qi, AD; Zambon, AC1
Ko, WH; Wong, CH1
Baldetorp, B; Edvinsson, L; Erlinge, D; Harden, TK; Hou, M; Kuhn, CM; Lazarowski, E; Möller, S; Pendergast, W1
Belloc, I; Chaulet, H; Desgranges, C; Dupuch, F; Gadeau, AP; Pillois, X1
Kaulich, M; Müller, CE; Qurishi, R1
Minami, M; Nakagawa, T; Okada, M; Satoh, M1
Edvinsson, L; Erlinge, D; Hou, M; Malmsjö, M; Pendergast, W1
Meng, H; Nakazawa, H; Sakakibara, M; Tokimasa, T1
Edwards, FA; Price, GD; Robertson, SJ1
Garvey, KA; Keirstead, SA; Reifel Saltzberg, JM1
Choi, BH; Kim, KT; Lee, H; Lee, SK; Suh, BC1
Boucsein, C; Färber, K; Hanisch, UK; Kettenmann, H; Pavlovic, S; Zacharias, R1
Bernardi, A; Horn, AP; Jacques-Silva, MC; Lenz, G; Morrone, FB; Rodnight, R; Schwartsmann, G1
Dranoff, JA; Gaça, MD; Kruglov, EA; Ogawa, M; Robson, SC; Sévigny, J; Wells, RG1
Choi, SJ; Kim, JH; Kim, MH; Kim, SJ; Koh, DS; Lee, JE; Min, KM; Nam, JH; Uhm, DY1
Adinolfi, E; Baricordi, OR; Chiozzi, P; Di Virgilio, F; Morelli, A; Rizzo, R; Solini, A1
West, TP1
Feng, F; Monde, K; Niikura, K; Nishimura, S; Noguchi, T; Ohta, T; Okuyama, K; Sadamoto, R1
Biederbick, A; Elsässer, HP; Rösser, R; Storre, J1
Habara, Y; Takahashi-Iwanaga, H1
Berod, L; Elsner, P; Geissler, M; Girolomoni, G; Herouy, Y; Idzko, M; Mockenhaupt, M; Norgauer, J; Panther, E; Sorichter, S1
Atterbury-Thomas, AE; Calvert, JA; Evans, RJ; Forsythe, ID; Gachet, C; Leon, C1
Dixon, SJ; Du, X; Korcok, J; Raimundo, LN; Sims, SM1
Jacobson, KA; Shainberg, A; Shneyvays, V; Yitzhaki, S1
Assairi, L; Barzu, O; Briozzo, P; Evrin, C; Gilles, AM; Joly, N; Meyer, P1
Kunzelmann, K; Schreiber, R1
Chootip, K; Gurney, AM; Kennedy, C1
Dale, L; Devader, C; Thomas, GM; Webb, RJ1
Chen, YW; Erlinge, D; Gomez, MF; Molkentin, JD; Nilsson, J; Nilsson, LM1
Arner, A; Balogh, J; Borna, C; Dou, Y; Erlinge, D; Jacobson, KA; Joshi, BV; Lazarowski, E; Wang, L; Wihlborg, AK1
Arnett, TR; Burnstock, G; Knight, GE; Orriss, IR; Ranasinghe, S1
Horowitz, B; Koh, SD; Monaghan, KP; Ro, S; Sanders, KM; Yeom, J1
de la Blanca, EP; Jiménez, E; Montiel, M1
Arthur, DB; Insel, PA; Taupenot, L1
Alexander, SP; Latif, ML; Ralevic, V; Rayment, SJ1
Housley, GD; Soeller, C; Thorne, PR; Vlajkovic, SM; Wang, CJ; Zimmermann, H1
Boarder, MR; Dixon, CJ; Hall, JF; Luo, Y; White, PJ1
Gohlke, M; Grunow, D; Renner, AB; Reutter, W; Rieger, K; Zimmermann-Kordmann, M1
Jang, SH; Lee, SY; Maniak, PJ; O'Grady, SM; Palmer, ML; Ryu, PD1
Crooke, A; Guzmán-Aranguez, AI; Markovskaya, A; Peral, A; Pintor, J; Ziganshin, AU1
Gui, Y; Jankowski, J; Jankowski, V; Walsh, MP; Zheng, XL1
Degagné, E; Dupuis, AA; Gendron, FP; Grbic, DM; Langlois, C1
Blanchard, F; Cacan, R; Chirat, F; Goergen, JL; Guedon, E; Kochanowski, N; Marc, A1
Blero, D; Boeynaems, JM; Bouffioux, C; Bruyns, C; Caspers, L; Communi, D; Horckmans, M; Makhoul, M; Marcet, B; Relvas, LJ; Willermain, F1
Alonso, GL; Egido, P; Gonzalez, DA; Lacapere, JJ; Ostuni, MA; Peranzi, G1
Csernoch, L; Fodor, J; Gergely, P; Gönczi, M; Juhász, T; Matta, C; Oláh, T; Szíjgyártó, Z; Zákány, R1
Chen, X; Jou, MJ; Yoon, J1
Carter, RL; Cosyn, L; Jacobson, KA; Joshi, BV; Kendall Harden, T; Ko, H; Van Calenbergh, S1
Benikhlef, N; Ciudad, M; Droin, N; Ducoroy, P; Dufour, E; Fenaux, P; Fontenay, M; Guery, L; Hendra, JB; Jacquel, A; Jooste, V; Kosmider, O; Pecqueur, D; Quesnel, B; Racoeur, C; Solary, E; Truntzer, C1
Damerow, S; Führing, J; Haselhorst, T; Lamerz, AC; Routier, FH; von Itzstein, M; Zarnovican, P1
Haynes, JM; Khaira, SK; Pouton, CW1
Arellano, RO; Garay, E; Vázquez-Cuevas, FG; Zárate-Díaz, EP1
Adams, SD; Pécsi, I; Sellers, JR; Simon, I; Szabó, JE; Tóth, J; Vértessy, BG1
Correia-de-Sá, P; Costa, MA; Ferreirinha, F; Freitas, R; Magalhães-Cardoso, MT; Neves, JM; Noronha-Matos, JB; Pelletier, J; Sévigny, J1
Matsumoto, T; Tostes, RC; Webb, RC1
Grählert, J; Mastropaolo, M; Mulè, F; Serio, R; Zizzo, MG1
An, HJ; Ji, YG; Kim, OJ; Ko, T; Lee, DH1
Gurney, AM; Kennedy, C; Mitchell, C; Syed, NI1
Fry, CH; Ikeda, Y; Jabr, RI; Kanai, AJ; McCarthy, C; Young, JS1
Aydin, S; Cansev, M; Coskun, N; Gumus, A; Isik, E; Orhan, F; Sevinc, C; Turkyilmaz, M; Ulus, IH; Wurtman, RJ; Yaylagul, EO1
Correa, G; Coutinho, CM; Coutinho-Silva, R; Marinho, Y; Moreira-Souza, AC; Santoro, GF; Vommaro, RC1
Bekhite, MM; Figulla, HR; Mazrouei, S; Sauer, H; Sharifpanah, F; Wartenberg, M1
Kowal, JM; Novak, I; Yegutkin, GG1
Aburakawa, S; Ito, K; Kasai, K; Nakamura, T; Nakano, M; Soma, N; Takami, H; Yuno, T1
Bäurer, S; Kramer, M; Lämmerhofer, M; Polnick, S; Sánchez-Muñoz, OL1
Ali, S; Fountain, SJ; Turner, J1
Katome, T; Kobayashi, T; Kojima, M; Matsumoto, T; Taguchi, K; Takayanagi, K1
Belosludtseva, NV; Bulion, VV; Evdokimova, NR; Krylova, IB; Mironova, GD; Rodionova, OM; Selina, EN; Shigaeva, MI1
Dales, MO; Drummond, RM; Gurney, AM; Kennedy, C; Mitchell, C1
Arı, M; Cansev, M; Kılınç, E; Özlük, K; Sağdilek, E1

Reviews

4 review(s) available for uridine diphosphate and uridine triphosphate

ArticleYear
Purine and pyrimidine (P2) receptors as drug targets.
    Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19

    Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate

2002
Extracellular metabolism of nucleotides in the nervous system.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:6

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Hydrolysis; Nervous System; Uridine Diphosphate; Uridine Triphosphate

1996
Potential signalling roles for UTP and UDP: sources, regulation and release of uracil nucleotides.
    Trends in pharmacological sciences, 1997, Volume: 18, Issue:10

    Topics: Animals; Humans; Signal Transduction; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate

1997
Identification of the P2Y(12) receptor: a novel member of the P2Y family of receptors activated by extracellular nucleotides.
    Molecular pharmacology, 2001, Volume: 60, Issue:3

    Topics: Adenosine Triphosphate; Animals; Guanosine Triphosphate; Humans; Inosine Triphosphate; Membrane Proteins; Nucleotides; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate

2001

Other Studies

146 other study(ies) available for uridine diphosphate and uridine triphosphate

ArticleYear
Cloning, functional expression and tissue distribution of the human P2Y6 receptor.
    Biochemical and biophysical research communications, 1996, May-15, Volume: 222, Issue:2

    Topics: Adenine Nucleotides; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; DNA, Complementary; Female; Gene Library; Humans; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; Leukocytes; Molecular Sequence Data; Open Reading Frames; Organ Specificity; Placenta; Pregnancy; Rats; Receptors, Purinergic P2; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Spleen; Thymus Gland; Transfection

1996
Synthesis and P2Y receptor activity of a series of uridine dinucleoside 5'-polyphosphates.
    Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2

    Topics: Calcium; Dinucleoside Phosphates; Humans; Protein Binding; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Spectrometry, Fluorescence; Structure-Activity Relationship; Transduction, Genetic; Tumor Cells, Cultured; Uracil Nucleotides

2001
Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.
    Journal of medicinal chemistry, 2002, Jan-03, Volume: 45, Issue:1

    Topics: Adenine Nucleotides; Animals; Bridged Bicyclo Compounds; Erythrocyte Membrane; Humans; In Vitro Techniques; Inositol Phosphates; Molecular Conformation; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Turkey; Uracil Nucleotides

2002
Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors.
    Journal of medicinal chemistry, 2006, Nov-30, Volume: 49, Issue:24

    Topics: Bridged Bicyclo Compounds; Cell Line, Tumor; Humans; Inositol Phosphates; Purinergic P2 Receptor Agonists; Purines; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Structure-Activity Relationship; Uracil Nucleotides; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2006
Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.
    Bioorganic & medicinal chemistry, 2008, Jun-15, Volume: 16, Issue:12

    Topics: Humans; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Structure-Activity Relationship; Uracil Nucleotides

2008
Identification of hydrolytically stable and selective P2Y(1) receptor agonists.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Biomimetics; Cell Line, Tumor; Drug Design; Gastric Juice; Humans; Hydrogen-Ion Concentration; Hydrolysis; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y1; Substrate Specificity; Temperature

2009
5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist.
    Journal of medicinal chemistry, 2010, Feb-25, Volume: 53, Issue:4

    Topics: Calcium; Cell Line, Tumor; Humans; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Structure-Activity Relationship; Transfection; Uridine Diphosphate

2010
Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications.
    Journal of medicinal chemistry, 2010, Jun-10, Volume: 53, Issue:11

    Topics: Cell Line, Tumor; Dinucleoside Phosphates; Esters; Humans; Imines; Models, Molecular; Polyphosphates; Protein Conformation; Purinergic P2 Receptor Agonists; Pyrimidines; Receptors, Purinergic P2; Ribonucleotides; Structure-Activity Relationship; Substrate Specificity

2010
Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors.
    Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8

    Topics: Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Purinergic Agonists; Spectrometry, Mass, Electrospray Ionization; Uracil Nucleotides

2011
Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Boranes; Calcium; Cell Line, Tumor; Dinucleoside Phosphates; Drug Stability; Humans; Hydrolysis; Models, Molecular; Molecular Conformation; Phosphoric Diester Hydrolases; Purinergic P2Y Receptor Agonists; Pyrophosphatases; Receptors, Purinergic P2Y; Stereoisomerism; Structure-Activity Relationship; Turkey

2012
Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues.
    Bioorganic & medicinal chemistry, 2012, Apr-01, Volume: 20, Issue:7

    Topics: Cell Line; Cell Proliferation; Humans; Organophosphonates; Purinergic P2Y Receptor Agonists; Receptors, Purinergic P2Y2; Uracil Nucleotides; Uridine Triphosphate

2012
UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety.
    Bioorganic & medicinal chemistry, 2012, Sep-15, Volume: 20, Issue:18

    Topics: Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Receptors, Purinergic P2; Structure-Activity Relationship; Uridine Triphosphate

2012
Development of [(3)H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([(3)H]PSB-12150): A Useful Tool for Studying GPR17.
    ACS medicinal chemistry letters, 2014, Apr-10, Volume: 5, Issue:4

    Topics:

2014
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-P
    Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9

    Topics: Drug Design; Drug Stability; Enzyme Inhibitors; Humans; Hydrolysis; Inhibitory Concentration 50; Molecular Docking Simulation; Phosphoric Diester Hydrolases; Protein Conformation; Pyrophosphatases; Structure-Activity Relationship; Substrate Specificity; Uracil Nucleotides

2018
Characteristics of galactosyl and fucosyl transfer to bovine rhodopsin.
    Experimental eye research, 1978, Volume: 26, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cattle; Fucose; Galactose; Galactosyltransferases; Hexosyltransferases; Hydrogen-Ion Concentration; In Vitro Techniques; Nucleotides; Photoreceptor Cells; Polyethylene Glycols; Retinal Pigments; Rhodopsin; Stimulation, Chemical; Uridine Diphosphate; Uridine Triphosphate

1978
Axonal transport of nucleosides, nucleotides and 4S RNA in the neonatal rat visual system.
    Brain research, 1979, Jun-22, Volume: 169, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Axonal Transport; Dominance, Cerebral; Electrophoresis, Polyacrylamide Gel; Geniculate Bodies; Male; Nucleosides; Nucleotides; Optic Nerve; Rats; RNA; Uridine; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate; Visual Pathways

1979
Studies on the inhibition of hepatic microsomal glucuronidation by uridine nucleotides or adenosine triphosphate.
    Medical biology, 1979, Volume: 57, Issue:5

    Topics: Adenosine Triphosphate; Animals; Estradiol; Glucuronosyltransferase; Guinea Pigs; Male; Mice; Microsomes, Liver; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Diphosphate Glucuronic Acid; Uridine Diphosphate Sugars; Uridine Triphosphate

1979
A rapid quantitative method for measuring UTP, UDP, and UMP in the picomole range.
    Analytical biochemistry, 1977, Volume: 83, Issue:1

    Topics: Microchemistry; Nucleoside-Diphosphate Kinase; Pyrophosphatases; Uracil Nucleotides; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate; UTP-Glucose-1-Phosphate Uridylyltransferase

1977
Distribution of erythrocyte nucleotides in pyrimidine 5'-nucleotidase deficiency.
    British journal of haematology, 1979, Volume: 43, Issue:3

    Topics: Adenosine Triphosphate; Anemia, Hemolytic, Congenital Nonspherocytic; Anemia, Pernicious; Cytidine Diphosphate; Cytidine Monophosphate; Erythrocytes; Humans; Infant; Nucleotidases; Pyrimidine Nucleotides; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

1979
Concentration of uracil nucleotides and UDP-glucose in mouse liver after partial hepatectomy.
    The International journal of biochemistry, 1978, Volume: 9, Issue:7

    Topics: Animals; Hepatectomy; Liver; Liver Regeneration; Male; Mice; Uracil Nucleotides; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars; Uridine Monophosphate; Uridine Triphosphate

1978
Effect of nucleotides on the cytosolic free calcium activity and inositol phosphate formation in human glomerular epithelial cells.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Adenosine Triphosphate; Calcium; Cells, Cultured; Cytosol; Down-Regulation; Epithelium; Fura-2; Inosine Triphosphate; Inositol Phosphates; Kidney Glomerulus; Nucleotides; Protein Kinase C; Spectrometry, Fluorescence; Suramin; Tetradecanoylphorbol Acetate; Uridine Diphosphate; Uridine Triphosphate

1992
Identification of lysyl residues located at the substrate-binding site in UDP-glucose pyrophosphorylase from potato tuber: affinity labeling with uridine di- and triphosphopyridoxals.
    Biochemistry, 1991, Sep-03, Volume: 30, Issue:35

    Topics: Affinity Labels; Amino Acid Sequence; Binding Sites; Enzyme Activation; Lysine; Molecular Sequence Data; Pyridoxal Phosphate; Solanum tuberosum; Substrate Specificity; Uridine Diphosphate; Uridine Triphosphate; UTP-Glucose-1-Phosphate Uridylyltransferase

1991
A comparison of rapid adenine nucleotide incorporation into phosphoglyceroyl-ATP and into RNA-like species in perfused rat heart.
    Biochimica et biophysica acta, 1987, Feb-18, Volume: 927, Issue:2

    Topics: Adenosine Triphosphate; Animals; Dactinomycin; Glycerophosphates; Myocardium; Rats; RNA; Transcription, Genetic; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Triphosphate

1987
Endothelium-dependent relaxation by uridine tri- and diphosphate in isolated human pial vessels.
    Blood vessels, 1987, Volume: 24, Issue:3

    Topics: Blood Vessels; Endothelium; Humans; In Vitro Techniques; Pia Mater; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasodilation

1987
De novo pyrimidine nucleotide biosynthesis in isolated rat glomeruli.
    Kidney international, 1986, Volume: 30, Issue:1

    Topics: Animals; Basement Membrane; Buffers; In Vitro Techniques; Kidney Glomerulus; Male; Orotic Acid; Pyrimidine Nucleotides; Rats; Rats, Inbred F344; Uracil Nucleotides; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Diphosphate Glucuronic Acid; Uridine Triphosphate

1986
Biochemical approaches to enhancement of antitumor drug selectivity: selective protection of cells from 6-thioguanine and 6-mercaptopurine by adenosine.
    Cancer treatment reports, 1980, Volume: 64, Issue:12

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Count; Cell Line; Drug Interactions; Drug Resistance; Liver Neoplasms, Experimental; Mercaptopurine; Phosphoribosyl Pyrophosphate; Rats; Thioguanine; Uridine Diphosphate; Uridine Triphosphate

1980
Preventive effects of 5-fluorouridine and uridine on d-galactosamine-induced liver injury.
    Experimental and molecular pathology, 1981, Volume: 34, Issue:2

    Topics: Animals; Cell Nucleolus; Chemical and Drug Induced Liver Injury; Female; Galactosamine; Liver; Rats; RNA; Uridine; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars; Uridine Triphosphate

1981
[Cardiac uracil nucleotides and glycogen: effect of uridine and ribose administration in the rat].
    Journal de physiologie, 1982, Volume: 78, Issue:3

    Topics: Animals; Female; Glycogen; Isoproterenol; Myocardium; Rats; Rats, Inbred Strains; Ribose; Uracil Nucleotides; Uridine; Uridine Diphosphate; Uridine Triphosphate

1982
Extracellular nucleotides potentiate the cytosolic Ca2+, but not cyclic adenosine 3', 5'-monophosphate response to parathyroid hormone in rat osteoblastic cells.
    Endocrinology, 1995, Volume: 136, Issue:4

    Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cell Line; Cyclic AMP; Cytosol; Drug Synergism; Kinetics; Nucleotides; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Rats; Receptors, Purinergic P2; Signal Transduction; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate

1995
The increase in the intracellular Ca2+ concentration induced by mechanical stimulation is propagated via release of pyrophosphorylated nucleotides in mammary epithelial cells.
    Pflugers Archiv : European journal of physiology, 1994, Volume: 427, Issue:5-6

    Topics: Adenosine Triphosphate; Animals; Calcium; Epithelial Cells; Epithelium; Female; Fura-2; Mammary Neoplasms, Experimental; Mice; Nucleotides; Phosphorylation; Physical Stimulation; Suramin; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

1994
An approach to the in vitro study of the UTP/UDPglucose/UDP moiety-conserved cycle.
    Biochimica et biophysica acta, 1994, Aug-18, Volume: 1200, Issue:3

    Topics: Animals; Glycogen Synthase; Kinetics; Models, Chemical; Nucleoside-Diphosphate Kinase; Rabbits; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Triphosphate; UTP-Glucose-1-Phosphate Uridylyltransferase

1994
Discrimination of fluorinated uridine metabolites in N-417 small cell lung cancer cell extracts via 19F- and 31P-NMR.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:2

    Topics: Carcinoma, Small Cell; Fluorine; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Phosphorus; Tumor Cells, Cultured; Uridine; Uridine Diphosphate; Uridine Diphosphate Glucose; Uridine Diphosphate Glucuronic Acid; Uridine Diphosphate N-Acetylgalactosamine; Uridine Diphosphate N-Acetylglucosamine; Uridine Diphosphate Sugars; Uridine Triphosphate

1994
Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C.
    The Journal of biological chemistry, 1994, Apr-22, Volume: 269, Issue:16

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Cell Line; Colonic Neoplasms; Enzyme Activation; Glioma; GTP-Binding Proteins; Humans; Inositol Phosphates; Kinetics; Pertussis Toxin; Phospholipases A; Phospholipases A2; Rats; Receptors, Cell Surface; Ribonucleotides; Time Factors; Tumor Cells, Cultured; Type C Phospholipases; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate; Virulence Factors, Bordetella

1994
Release of arachidonic acid via Ca2+ increase stimulated by pyrophosphonucleotides and bradykinin in mammary tumour cells.
    Cell biochemistry and function, 1995, Volume: 13, Issue:4

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Bradykinin; Calcium; Female; Mammary Neoplasms, Experimental; Mice; Nucleotides, Cyclic; Receptors, Bradykinin; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

1995
UTP- and ATP-triggered transmitter release from rat sympathetic neurones via separate receptors.
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; In Vitro Techniques; Neurons; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Superior Cervical Ganglion; Sympathetic Nervous System; Uridine Diphosphate; Uridine Triphosphate

1995
Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.
    Molecular pharmacology, 1996, Volume: 50, Issue:2

    Topics: Adenosine Triphosphate; Animals; Humans; Rats; Receptors, Purinergic P2; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

1996
A novel G protein-coupled P2 purinoceptor (P2Y3) activated preferentially by nucleoside diphosphates.
    Molecular pharmacology, 1996, Volume: 50, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Calcium; Chick Embryo; DNA, Complementary; GTP-Binding Proteins; Humans; Molecular Sequence Data; Receptors, Purinergic P2; RNA, Messenger; Transfection; Uridine Diphosphate; Uridine Triphosphate; Xenopus laevis

1996
Chemienzymatic synthesis of uridine nucleotides labeled with [15N] and [13C].
    Analytical biochemistry, 1995, Dec-10, Volume: 232, Issue:2

    Topics: Adenosine Triphosphate; Bacterial Proteins; Carbon Isotopes; Enzymes; Fungal Proteins; Glucose; Isotope Labeling; Magnetic Resonance Spectroscopy; NADP; Nitrogen Isotopes; Phosphorylation; Recombinant Proteins; Ribulosephosphates; Uracil; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

1995
Evidence that most high-affinity ATP binding sites on aortic endothelial cells and membranes do not correspond to P2 receptors.
    European journal of pharmacology, 1996, Jun-27, Volume: 307, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Binding Sites; Binding, Competitive; Cattle; Cell Membrane; Cells, Cultured; Cytidine Triphosphate; Endothelium; In Vitro Techniques; Inositol Phosphates; Kinetics; Models, Biological; Osmolar Concentration; Phosphorus Radioisotopes; Protein Binding; Receptors, Purinergic; Receptors, Purinergic P2; Sulfur Radioisotopes; Uridine Diphosphate; Uridine Triphosphate

1996
Analysis of individual purine and pyrimidine nucleoside di- and triphosphates and other cellular metabolites in PCA extracts by using multinuclear high resolution NMR spectroscopy.
    Magnetic resonance in medicine, 1996, Volume: 36, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cytidine Diphosphate; Cytidine Triphosphate; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Magnetic Resonance Spectroscopy; Purine Nucleotides; Pyrimidine Nucleotides; Uridine Diphosphate; Uridine Triphosphate

1996
UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y2 receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-18, Volume: 94, Issue:6

    Topics: Calcium; Cells, Cultured; Chlorides; Hexokinase; Humans; Inositol Phosphates; Kinetics; Nasal Mucosa; Nucleoside-Diphosphate Kinase; Receptors, Cell Surface; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Turbinates; Uridine Diphosphate; Uridine Triphosphate

1997
Pharmacological and second messenger signalling selectivities of cloned P2Y receptors.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:6

    Topics: Adenosine Triphosphate; Animals; Astrocytoma; Cloning, Molecular; Enzyme Activation; Glioma; Humans; Inositol Phosphates; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Second Messenger Systems; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

1996
Enzymatic production of pyrimidine nucleotides using Corynebacterium ammoniagenes cells and recombinant Escherichia coli cells: enzymatic production of CDP-choline from orotic acid and choline chloride (Part I).
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:6

    Topics: Carbon-Nitrogen Ligases; Choline; Chromatography, High Pressure Liquid; Corynebacterium; Cytidine Diphosphate Choline; Cytidine Triphosphate; Escherichia coli; Gene Expression Regulation, Enzymologic; Ligases; Orotic Acid; Phosphoribosyl Pyrophosphate; Plasmids; Pyrimidine Nucleotides; Saccharomyces cerevisiae; Substrate Specificity; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

1997
Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists.
    The Journal of biological chemistry, 1997, Aug-15, Volume: 272, Issue:33

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Humans; Nucleoside-Diphosphate Kinase; Purinergic P2 Receptor Agonists; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

1997
Involvement of protein kinase C in the UTP-mediated potentiation of cyclic AMP accumulation in mouse J774 macrophages.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cells, Cultured; Cyclic AMP; Ionomycin; Isoenzymes; Macrophages; Mice; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Uridine Diphosphate; Uridine Triphosphate; Virulence Factors, Bordetella

1997
Adenosine triphosphate activates a noninactivating K+ current in adrenal cortical cells through nonhydrolytic binding.
    The Journal of general physiology, 1997, Volume: 110, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cattle; Cells, Cultured; Chelating Agents; Edetic Acid; Electric Conductivity; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Ion Channel Gating; Patch-Clamp Techniques; Potassium; Potassium Channels; Uridine Diphosphate; Uridine Triphosphate

1997
UTP induces vascular responses in the isolated and perfused canine epicardial coronary artery via UTP-preferring P2Y receptors.
    British journal of pharmacology, 1997, Volume: 122, Issue:8

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antinematodal Agents; Coronary Vessels; Diltiazem; Dogs; Female; Hexokinase; Indomethacin; Male; Protein Synthesis Inhibitors; Receptors, Purinergic P2; Saponins; Suramin; Triazines; Uridine Diphosphate; Uridine Triphosphate

1997
Activation of carbamoyl phosphate synthetase II by UDP-pyridoxal, an analogue of the inhibitor UTP.
    Biochemical Society transactions, 1997, Volume: 25, Issue:4

    Topics: Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Enzyme Activation; Enzyme Inhibitors; Kinetics; Pyridoxal Phosphate; Structure-Activity Relationship; Uridine Diphosphate; Uridine Triphosphate

1997
Nucleotide-evoked calcium signals and anion secretion in equine cultured epithelia that express apical P2Y2 receptors and pyrimidine nucleotide receptors.
    British journal of pharmacology, 1998, Volume: 124, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anions; Calcium; Cell Polarity; Cells, Cultured; Epithelial Cells; Horses; Nucleotides; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Sweat Glands; Uridine Diphosphate; Uridine Triphosphate

1998
Intracellular nucleotide-mediated gating of SUR/Kir6.0 complex potassium channels expressed in a mammalian cell line and its modification by pinacidil.
    The Journal of physiology, 1998, Sep-15, Volume: 511 ( Pt 3)

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Electrophysiology; Humans; Ion Channel Gating; Kidney; Kinetics; Mammals; Mixed Function Oxygenases; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Uridine Diphosphate; Uridine Triphosphate; Vasodilator Agents

1998
Selective inhibition of M-type potassium channels in rat sympathetic neurons by uridine nucleotide preferring receptors.
    British journal of pharmacology, 1998, Volume: 124, Issue:6

    Topics: Adenine Nucleotides; Animals; Calcium Channels; Guanine Nucleotides; Hydrolysis; Ion Channel Gating; Neurons; Potassium Channel Blockers; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Suramin; Sympathetic Nervous System; Triazines; Uridine Diphosphate; Uridine Triphosphate

1998
Pyrimidine nucleotide-stimulated thromboxane A2 release from cultured glia.
    Cellular and molecular neurobiology, 1998, Volume: 18, Issue:5

    Topics: Aminobenzoates; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cerebral Cortex; Chlorobenzoates; Cinnamates; Culture Media, Serum-Free; Cytidine Triphosphate; Drug Interactions; Ionomycin; Ionophores; Leucine; Neuroglia; ortho-Aminobenzoates; Phospholipases A; Phospholipases A2; Rats; Thromboxane A2; Thymine Nucleotides; Uridine Diphosphate; Uridine Triphosphate

1998
Functional evidence for a novel suramin-insensitive pyrimidine receptor in rat small pulmonary arteries.
    Circulation research, 1998, Nov-02, Volume: 83, Issue:9

    Topics: Animals; Chloride Channels; Male; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

1998
Pyrimidinoceptor potentiation by ATP in NG108-15 cells.
    FEBS letters, 1998, Nov-13, Volume: 439, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Edetic Acid; Inositol Phosphates; Mice; Rats; Tumor Cells, Cultured; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

1998
Dual coupling of heterologously-expressed rat P2Y6 nucleotide receptors to N-type Ca2+ and M-type K+ currents in rat sympathetic neurones.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Animals; Calcium Channels; Dose-Response Relationship, Drug; Pertussis Toxin; Potassium Channels; Rats; Receptors, Purinergic P2; Superior Cervical Ganglion; Uridine Diphosphate; Uridine Triphosphate; Virulence Factors, Bordetella

1999
Regulation of vascular tone by UTP and UDP in isolated rat intrapulmonary arteries.
    European journal of pharmacology, 1999, Apr-09, Volume: 370, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Drug Interactions; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation

1999
Only pyrimidinoceptors are functionally expressed in mouse neuroblastoma cell lines.
    Molecular cell biology research communications : MCBRC, 1999, Volume: 1, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Humans; Mice; Neuroblastoma; Rats; Receptors, Purinergic P2; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

1999
Pyrimidine nucleotide-evoked inhibition of cyclic AMP accumulation in equine epithelial cells.
    Experimental physiology, 1999, Volume: 84, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Calcium; Cell Line, Transformed; Cyclic AMP; Enzyme Inhibitors; Epinephrine; Epithelial Cells; Horses; Pertussis Toxin; Receptors, Purinergic P2; Sweat Glands; Thapsigargin; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate; Virulence Factors, Bordetella

1999
Congestive heart failure induces downregulation of P2X1-receptors in resistance arteries.
    Cardiovascular research, 1999, Volume: 43, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Gene Expression Regulation; Heart Failure; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uridine Diphosphate; Uridine Triphosphate; Vascular Resistance; Vasoconstriction

1999
Effect of luminal nucleotides on Cl- secretion and Na+ absorption in distal bronchi.
    Pflugers Archiv : European journal of physiology, 1999, Volume: 438, Issue:5

    Topics: Absorption; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bronchi; Calcium; Chelating Agents; Chlorides; Egtazic Acid; Electric Conductivity; Microelectrodes; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sodium; Swine; Thapsigargin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate

1999
Analysis of sugar metabolism in an EPS producing Lactococcus lactis by 31P NMR.
    Journal of biotechnology, 2000, Jan-28, Volume: 77, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Food Microbiology; Fructosediphosphates; Genes, Bacterial; Lactococcus lactis; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Plasmids; Polysaccharides, Bacterial; Uridine Diphosphate; Uridine Triphosphate

2000
M-type K+ currents in rat cultured thoracolumbar sympathetic neurones and their role in uracil nucleotide-evoked noradrenaline release.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Adenosine Triphosphate; Animals; Barium; Cells, Cultured; Female; Ganglia, Sympathetic; Male; Membrane Potentials; Muscarinic Agonists; Neurons; Norepinephrine; Oxotremorine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium; Uridine Diphosphate; Uridine Triphosphate

2000
Evidence that rat hepatocytes co-express functional P2Y1 and P2Y2 receptors.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; DNA, Complementary; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Uridine Diphosphate; Uridine Triphosphate

2000
In vivo dynamic real-time monitoring and quantification of platelet-thrombus formation: use of a local isotope detector.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anticoagulants; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Computer Systems; Fibrinolytic Agents; Gene Expression; Heparin; Indium Radioisotopes; Partial Thromboplastin Time; Plasminogen Activator Inhibitor 1; Radionuclide Imaging; RNA, Messenger; Swine; Thrombosis; Ultrasonography, Doppler; Uridine Diphosphate; Uridine Triphosphate

2000
P2Y receptor regulation of PAI-1 expression in vascular smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:3

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Gene Expression; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstrictor Agents

2000
Characterization of contractile P2 receptors in human coronary arteries by use of the stable pyrimidines uridine 5'-O-thiodiphosphate and uridine 5'-O-3-thiotriphosphate.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: Adenosine Triphosphate; Adolescent; Adult; Coronary Vessels; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Middle Aged; Polymerase Chain Reaction; Receptors, Purinergic P2; RNA, Messenger; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2000
Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations.
    The Journal of biological chemistry, 2000, Oct-06, Volume: 275, Issue:40

    Topics: Adenosine Triphosphate; Animals; Cell Line; Chromatography, High Pressure Liquid; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Luciferases; Nucleoside-Diphosphate Kinase; Phosphates; Phosphorylation; Pyrophosphatases; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2; Time Factors; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

2000
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery.
    British journal of pharmacology, 2000, Volume: 131, Issue:1

    Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation

2000
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Arterioles; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Suramin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation

2001
Effect of uridine derivatives on myocardial stunning during postischemic reperfusion of rat heart.
    Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:10

    Topics: Animals; Animals, Outbred Strains; Coronary Circulation; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Rats; Uridine; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2000
Mechanisms of P2 receptor-evoked DNA synthesis in thyroid FRTL-5 cells.
    Journal of cellular physiology, 2001, Volume: 187, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; DNA; DNA Primers; DNA Replication; Enzyme Inhibitors; Flavonoids; Gene Expression; Genes, Immediate-Early; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Receptors, Purinergic P2; Thymidine; Thyroid Gland; Transcription, Genetic; Tritium; Uridine Diphosphate; Uridine Triphosphate

2001
Pharmacological characterisation of pyrimidinoceptor responses in NG108-15 cells.
    European journal of pharmacology, 2001, Volume: 415, Issue:2-3

    Topics: Adenosine; Analgesics; Animals; Antineoplastic Agents; Cell Line; Inositol Phosphates; Mice; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Suramin; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

2001
The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jun-15, Volume: 166, Issue:12

    Topics: Adenosine Triphosphate; Antigens, CD; CD83 Antigen; Cell Differentiation; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendritic Cells; Dose-Response Relationship, Immunologic; Drug Synergism; Humans; Immunoglobulins; Interleukin-12; Lipopolysaccharides; Membrane Glycoproteins; Monocytes; Receptors, Purinergic P2; RNA, Messenger; Signal Transduction; Thionucleotides; Tumor Necrosis Factor-alpha; Uridine Diphosphate; Uridine Triphosphate

2001
Apical P2Y4 purinergic receptor controls K+ secretion by vestibular dark cell epithelium.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Ear, Inner; Epithelium; Female; Gerbillinae; Humans; Membrane Potentials; Molecular Sequence Data; Potassium; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Suramin; Uridine Diphosphate; Uridine Triphosphate

2001
Extracellular nucleotides induce arterial smooth muscle cell migration via osteopontin.
    Circulation research, 2001, Oct-26, Volume: 89, Issue:9

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Calcium; Cell Movement; Cells, Cultured; Chemotaxis; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nucleotides; Oligopeptides; Osteopontin; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Sialoglycoproteins; Uridine Diphosphate; Uridine Triphosphate

2001
P2X2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Dec-01, Volume: 21, Issue:23

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Cochlea; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Flufenamic Acid; Gadolinium; Gerbillinae; Hearing; In Vitro Techniques; Ion Channels; Ion Transport; Microelectrodes; Physical Stimulation; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin; Uridine Diphosphate; Uridine Triphosphate; Vestibule, Labyrinth; Vibration

2001
An arginine/glutamine difference at the juxtaposition of transmembrane domain 6 and the third extracellular loop contributes to the markedly different nucleotide selectivities of human and canine P2Y11 receptors.
    Molecular pharmacology, 2001, Volume: 60, Issue:6

    Topics: Adenine Nucleotides; Amino Acid Substitution; Animals; Arginine; Cyclic AMP; Dogs; Glutamine; Humans; Hydrolysis; Inositol; Lipid Metabolism; Membrane Proteins; Protein Conformation; Protein Structure, Tertiary; Receptors, Purinergic P2; Uridine Diphosphate; Uridine Triphosphate

2001
Stimulation of Cl- secretion via membrane-restricted Ca2+ signaling mediated by P2Y receptors in polarized epithelia.
    The Journal of biological chemistry, 2002, Mar-15, Volume: 277, Issue:11

    Topics: Adenosine Triphosphate; Animals; Calcium Signaling; Cell Line; Cell Polarity; Chlorides; Dose-Response Relationship, Drug; Epithelium; Horses; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thapsigargin; Uridine Diphosphate; Uridine Triphosphate

2002
UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y(6) receptors.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Animals; Aorta; Cell Survival; Cells, Cultured; Cyclic AMP; DNA; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Growth Substances; Inositol Phosphates; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Protein Kinases; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Thymidine; Tritium; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

2002
Nucleotide receptors involved in UTP-induced rat arterial smooth muscle cell migration.
    Circulation research, 2002, Apr-05, Volume: 90, Issue:6

    Topics: Animals; Cell Movement; Cells, Cultured; Gene Expression Regulation; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Uridine Diphosphate; Uridine Triphosphate

2002
Fast, efficient capillary electrophoresis method for measuring nucleotide degradation and metabolism.
    Journal of chromatography. A, 2002, Apr-05, Volume: 952, Issue:1-2

    Topics: Adenosine Triphosphate; Electrophoresis, Capillary; Hexokinase; Hydrolysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

2002
Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: Adenosine Triphosphate; Analgesics; Animals; Disease Models, Animal; Hot Temperature; Injections, Spinal; Male; Neuralgia; Pain; Posture; Pressure; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Time Factors; Uridine; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2002
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between contractile cerebrovascular P2 receptors.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Basilar Artery; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2003
Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid can antagonize the purinoceptor-mediated inhibition of M-current in bullfrog sympathetic neurons.
    Neuroscience letters, 2003, Feb-06, Volume: 337, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amyloid beta-Protein Precursor; Animals; Guanosine Triphosphate; Membrane Potentials; Neurons; Potassium Channels; Purinergic Antagonists; Pyridoxal Phosphate; Rana catesbeiana; Receptors, Purinergic; Sympathetic Nervous System; Uridine Diphosphate; Uridine Triphosphate

2003
Long-term potentiation of glutamatergic synaptic transmission induced by activation of presynaptic P2Y receptors in the rat medial habenula nucleus.
    The European journal of neuroscience, 2003, Volume: 17, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Habenula; In Vitro Techniques; Long-Term Potentiation; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Synaptic Transmission; Triazines; Uridine Diphosphate; Uridine Triphosphate

2003
Pharmacological characterization of P2Y receptor subtypes on isolated tiger salamander Müller cells.
    Glia, 2003, Apr-15, Volume: 42, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ambystoma; Animals; Calcium; Calcium Signaling; Cell Communication; Cells, Cultured; Fura-2; Neuroglia; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Retina; Signal Transduction; Uridine Diphosphate; Uridine Triphosphate

2003
Attenuation of signal flow from P2Y6 receptor by protein kinase C-alpha in SK-N-BE(2)C human neuroblastoma cells.
    Journal of neurochemistry, 2003, Volume: 85, Issue:4

    Topics: Bradykinin; Calcium; Cell Differentiation; Cholinergic Agonists; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Neuroblastoma; Nucleotides; Pertussis Toxin; Protein Kinase C; Protein Kinase C-alpha; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

2003
Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro.
    The European journal of neuroscience, 2003, Volume: 17, Issue:11

    Topics: Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Brain; Calcium; Cell Survival; Cells, Cultured; Chloride Channels; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Lipopolysaccharides; Magnesium; Membrane Potentials; Mice; Mice, Inbred C57BL; Microglia; Neural Conduction; Nitric Oxide; Patch-Clamp Techniques; Potassium Channels; Receptors, Purinergic; Time Factors; Uridine Diphosphate; Uridine Triphosphate; Vasodilator Agents

2003
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.
    Journal of neuro-oncology, 2003, Volume: 64, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Brain Neoplasms; Cell Division; DNA; Extracellular Space; Glioma; Humans; Nucleosides; Nucleotides; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purines; Pyrimidines; Receptors, Purinergic P1; Receptors, Purinergic P2; Signal Transduction; Thymidine; Tumor Cells, Cultured; Uridine Diphosphate; Uridine Triphosphate

2003
Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Collagen Type I; Cytosol; Liver; Male; Nucleoside-Triphosphatase; Nucleotidases; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Uridine Diphosphate; Uridine Triphosphate

2004
Purinergic receptors coupled to intracellular Ca2+ signals and exocytosis in rat prostate neuroendocrine cells.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Membrane; Electric Capacitance; Electrophysiology; Exocytosis; Male; Microscopy, Fluorescence; Neurosecretory Systems; Prostate; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Uridine Diphosphate; Uridine Triphosphate

2004
Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Autocrine Communication; Cell Shape; Cytidine Triphosphate; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fibroblasts; Fibronectins; Gene Expression Regulation; Humans; Interleukin-6; Membrane Potentials; Paracrine Communication; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Uridine Diphosphate; Uridine Triphosphate

2004
Regulation of pyrimidine nucleotide formation in Pseudomonas taetrolens ATCC 4683.
    Microbiological research, 2004, Volume: 159, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspartate Carbamoyltransferase; Dihydroorotase; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Guanosine Triphosphate; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases Acting on CH-CH Group Donors; Pseudomonas; Pyrimidine Nucleotides; Transcription, Genetic; Uridine Diphosphate; Uridine Triphosphate

2004
Chemo-enzymatic synthesis of fluorinated 2-N-acetamidosugar nucleotides using UDP-GlcNAc pyrophosphorylase.
    Organic & biomolecular chemistry, 2004, Jun-07, Volume: 2, Issue:11

    Topics: Acetylgalactosamine; Acetylglucosamine; Carbohydrate Conformation; Escherichia coli; Nucleotidyltransferases; Uridine Diphosphate; Uridine Triphosphate

2004
The VSFASSQQ motif confers calcium sensitivity to the intracellular apyrase LALP70.
    BMC biochemistry, 2004, Jun-16, Volume: 5

    Topics: Amino Acid Motifs; Animals; Apyrase; Calcium; Chlorocebus aethiops; COS Cells; Lysosomes; Pyrophosphatases; Substrate Specificity; Uridine Diphosphate; Uridine Triphosphate

2004
Oscillatory calcium responses mediated by P2Y2 purinergic receptors in terminal Schwann cells of longitudinal lanceolate endings isolated from rat vibrissae.
    The Journal of comparative neurology, 2004, Jul-26, Volume: 475, Issue:3

    Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Calcium; Calcium Signaling; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Confocal; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Schwann Cells; Suramin; Time Factors; Triazines; Uridine Diphosphate; Uridine Triphosphate; Vibrissae; Xanthenes

2004
Characterization of the biological activities of uridine diphosphate in human dendritic cells: Influence on chemotaxis and CXCL8 release.
    Journal of cellular physiology, 2004, Volume: 201, Issue:2

    Topics: Actins; Calcium; Chemokines, CXC; Chemotaxis; Dendritic Cells; GTP-Binding Proteins; Humans; Intracellular Fluid; Receptors, Purinergic P2; Signal Transduction; Uridine Diphosphate; Uridine Triphosphate

2004
Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia.
    British journal of pharmacology, 2004, Volume: 143, Issue:5

    Topics: Animals; Calcium; Cells, Cultured; Female; Fluorescent Dyes; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Superior Cervical Ganglion; Suramin; Uridine Diphosphate; Uridine Triphosphate

2004
P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Active Transport, Cell Nucleus; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Bone and Bones; Calcium; Cell Nucleus; Cell Survival; Cells, Cultured; Cytosol; DNA Primers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoproteins; Inflammation; Ligands; Microscopy, Fluorescence; NF-kappa B; Osteoclasts; Osteoprotegerin; Proteasome Inhibitors; Purinergic P2 Receptor Agonists; Rabbits; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Transcription Factor RelA; Uridine Diphosphate; Uridine Triphosphate

2005
Involvement of uracil nucleotides in protection of cardiomyocytes from hypoxic stress.
    Biochemical pharmacology, 2005, Apr-15, Volume: 69, Issue:8

    Topics: Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Calcium Signaling; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Immunohistochemistry; L-Lactate Dehydrogenase; Myocytes, Cardiac; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Stress, Physiological; Suramin; Time Factors; Triazines; Type C Phospholipases; Uracil Nucleotides; Uridine; Uridine Diphosphate; Uridine Triphosphate

2005
Structure of Escherichia coli UMP kinase differs from that of other nucleoside monophosphate kinases and sheds new light on enzyme regulation.
    The Journal of biological chemistry, 2005, Jul-08, Volume: 280, Issue:27

    Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Crystallography; Enzyme Activation; Escherichia coli; Guanosine Triphosphate; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Phosphate Kinase; Phosphates; Protein Folding; Protein Structure, Quaternary; Threonine; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2005
Purinergic P2Y6 receptors induce Ca2+ and CFTR dependent Cl- secretion in mouse trachea.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2005, Volume: 16, Issue:1-3

    Topics: Adenosine Diphosphate; Amiloride; Animals; Base Sequence; Calcium; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; In Vitro Techniques; Ion Transport; Mice; Potassium; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; RNA, Messenger; Sodium; Trachea; Uridine Diphosphate; Uridine Triphosphate

2005
Multiple P2Y receptors couple to calcium-dependent, chloride channels in smooth muscle cells of the rat pulmonary artery.
    Respiratory research, 2005, Oct-26, Volume: 6

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cells, Cultured; Chloride Channels; Chlorine; Male; Membrane Potentials; Muscle Contraction; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2005
Xenopus apyrase (xapy), a secreted nucleotidase that is expressed during early development.
    Gene, 2006, Feb-15, Volume: 367

    Topics: Amino Acid Sequence; Animals; Apyrase; Base Sequence; Bedbugs; Cell Line; Codon; Codon, Initiator; Conserved Sequence; Culture Media, Conditioned; DNA, Complementary; Embryo, Nonmammalian; Endoplasmic Reticulum; Fluorescein; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Gene Expression Regulation, Developmental; Humans; In Situ Hybridization; Metamorphosis, Biological; Microscopy, Fluorescence; Molecular Sequence Data; Nucleotidases; Protein Structure, Tertiary; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, RNA; Sequence Homology, Amino Acid; Tissue Distribution; Transcription, Genetic; Uridine Diphosphate; Uridine Triphosphate; Xenopus

2006
High glucose activates nuclear factor of activated T cells in native vascular smooth muscle.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:4

    Topics: Animals; Aorta; Calcium Signaling; Cerebral Arteries; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Mice; Mice, Transgenic; Microscopy, Confocal; Muscle, Smooth, Vascular; NFATC Transcription Factors; Pyrazoles; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Transcriptional Activation; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2006
Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction.
    Circulation research, 2006, Apr-14, Volume: 98, Issue:7

    Topics: Aged; Animals; Anticoagulants; Cardiotonic Agents; Chest Pain; Female; Humans; Male; Mice; Mice, Inbred Strains; Middle Aged; Muscle Cells; Myocardial Contraction; Myocardial Infarction; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Uridine Diphosphate; Uridine Triphosphate

2006
Osteoblast responses to nucleotides increase during differentiation.
    Bone, 2006, Volume: 39, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Calcium; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Nucleotides; Osteoblasts; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; RNA, Messenger; Skull; Time Factors; Uridine Diphosphate; Uridine Triphosphate

2006
Nucleotide regulation of the voltage-dependent nonselective cation conductance in murine colonic myocytes.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channels, L-Type; Colon; Gene Expression Regulation; Ion Channel Gating; Mice; Mice, Inbred BALB C; Muscle Cells; Nucleotides; Protein Kinase C; Pyridoxal Phosphate; Receptors, Purinergic P2; RNA, Messenger; Second Messenger Systems; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

2006
P2Y receptors activate MAPK/ERK through a pathway involving PI3K/PDK1/PKC-zeta in human vein endothelial cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2006, Volume: 18, Issue:1-3

    Topics: Adenosine Triphosphate; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Mitogen-Activated Protein Kinases; Models, Biological; Pertussis Toxin; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Purinergic P2; Signal Transduction; Time Factors; Uridine Diphosphate; Uridine Triphosphate

2006
Nerve growth factor-stimulated neuronal differentiation induces changes in P2 receptor expression and nucleotide-stimulated catecholamine release.
    Journal of neurochemistry, 2007, Volume: 100, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Nerve Growth Factor; Neurons; Norepinephrine; Nucleotides; PC12 Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; RNA, Messenger; Sympathetic Nervous System; Uridine Diphosphate; Uridine Triphosphate

2007
Evidence for the expression of multiple uracil nucleotide-stimulated P2 receptors coupled to smooth muscle contraction in porcine isolated arteries.
    British journal of pharmacology, 2007, Volume: 150, Issue:5

    Topics: Animals; Blotting, Western; Coronary Vessels; Dose-Response Relationship, Drug; Ear; Gene Expression; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Swine; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2007
Activation-dependent trafficking of NTPDase2 in Chinese hamster ovary cells.
    The international journal of biochemistry & cell biology, 2007, Volume: 39, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Green Fluorescent Proteins; Hydrolysis; Intracellular Fluid; Microscopy, Confocal; Protein Transport; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Time Factors; Transfection; Uridine Diphosphate; Uridine Triphosphate

2007
A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenoviridae; Animals; Cell Cycle; Cell Proliferation; Cell Survival; Epidermal Growth Factor; Glycogen Phosphorylase; Hepatocytes; Inositol Phosphates; Insulin; Male; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; S Phase; Thionucleotides; TOR Serine-Threonine Kinases; Transfection; Uridine Diphosphate; Uridine Triphosphate

2007
Liver-specific increase of UTP and UDP-sugar concentrations in rats induced by dietary vitamin B6-deficiency and its relation to complex N-glycan structures of liver membrane-proteins.
    Glycoconjugate journal, 2007, Volume: 24, Issue:9

    Topics: Animals; Carbohydrates; Female; Lipids; Liver; Male; Membranes; Nucleotides; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Polysaccharides; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution; Uridine Diphosphate; Uridine Triphosphate; Vitamin B 6 Deficiency

2007
P2Y receptor regulation of sodium transport in human mammary epithelial cells.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:5

    Topics: Adenosine Triphosphate; Amiloride; Biological Transport; Calcium; Cells, Cultured; Charybdotoxin; Chelating Agents; Clotrimazole; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Epithelial Cells; Epithelial Sodium Channels; Humans; Hydrocortisone; Intermediate-Conductance Calcium-Activated Potassium Channels; Mammary Glands, Human; Membrane Potentials; Potassium Channel Blockers; Receptor, Adenosine A2B; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; RNA, Messenger; Sodium; Sodium Channel Blockers; Time Factors; Uridine Diphosphate; Uridine Triphosphate

2007
Hypotensive effect of UDP on intraocular pressure in rabbits.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Animals; Ciliary Body; Dose-Response Relationship, Drug; Glaucoma; Intraocular Pressure; Male; Ocular Hypertension; Rabbits; Receptors, Purinergic P2; Uridine Diphosphate; Uridine Triphosphate

2008
Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 294, Issue:4

    Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Endothelium, Vascular; In Vitro Techniques; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Uridine Diphosphate; Uridine Triphosphate; Vasodilation; Vasodilator Agents

2008
Intestinal inflammation increases the expression of the P2Y6 receptor on epithelial cells and the release of CXC chemokine ligand 8 by UDP.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Feb-15, Volume: 180, Issue:4

    Topics: Animals; Caco-2 Cells; Cell Line; Colitis; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; Interleukin-8; Intestinal Mucosa; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Phosphorylation; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Up-Regulation; Uridine Diphosphate; Uridine Triphosphate

2008
Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-gamma glycosylation during batch and fed-batch cultures of CHO cells.
    Biotechnology and bioengineering, 2008, Jul-01, Volume: 100, Issue:4

    Topics: Animals; Carbohydrate Metabolism; Cell Culture Techniques; Cell Line, Transformed; CHO Cells; Cricetinae; Cricetulus; Culture Media, Serum-Free; Galactose; Glycosylation; Interferon-gamma; Recombinant Proteins; Serum; Sialyltransferases; Uridine Diphosphate; Uridine Triphosphate

2008
Extracellular nucleotides and interleukin-8 production by ARPE cells: potential role of danger signals in blood-retinal barrier activation.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:3

    Topics: Adenosine Triphosphate; Blood-Retinal Barrier; Blotting, Western; Cell Line; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gene Expression; Humans; Interleukin-8; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Receptors, Purinergic P2; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Uridine Diphosphate; Uridine Triphosphate

2009
Characterization of a functional NTPDase in the endoplasmic reticulum of rat submandibular salivary gland.
    Physiological research, 2009, Volume: 58, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Endoplasmic Reticulum; Enzyme Inhibitors; Hydrolysis; Immunohistochemistry; Kinetics; Magnesium; Male; Manganese; Microscopy, Electron; Microsomes; Nucleotidases; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Submandibular Gland; Uridine Diphosphate; Uridine Triphosphate

2009
Ionotropic purinergic receptor P2X4 is involved in the regulation of chondrogenesis in chicken micromass cell cultures.
    Cell calcium, 2009, Volume: 45, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Culture Techniques; Cell Differentiation; Cell Membrane; Cells, Cultured; Chick Embryo; Chondrogenesis; Culture Media; Extracellular Matrix; Mesoderm; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Uridine Diphosphate; Uridine Triphosphate

2009
An "Off-On" type UTP/UDP selective fluorescent probe and its application to monitor glycosylation process.
    Organic letters, 2009, May-21, Volume: 11, Issue:10

    Topics: Fluorescent Dyes; Glycosylation; Molecular Structure; Organometallic Compounds; Perylene; Uridine Diphosphate; Uridine Triphosphate; Zinc

2009
Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.
    Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Line, Tumor; Humans; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Recombinant Proteins; Uridine Diphosphate; Uridine Triphosphate

2009
Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.
    Blood, 2010, Jan-07, Volume: 115, Issue:1

    Topics: alpha-Defensins; CD24 Antigen; Cell Differentiation; Cytokines; Granulocytes; Humans; Leukemia, Myelomonocytic, Chronic; Lipopolysaccharide Receptors; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Receptors, Purinergic P2; Uridine Diphosphate; Uridine Triphosphate

2010
Leishmania UDP-sugar pyrophosphorylase: the missing link in galactose salvage?
    The Journal of biological chemistry, 2010, Jan-08, Volume: 285, Issue:2

    Topics: Amino Acid Sequence; Animals; Evolution, Molecular; Galactosephosphates; Glucosephosphates; Glycocalyx; Leishmania major; Molecular Sequence Data; Nucleotidyltransferases; Protozoan Proteins; Substrate Specificity; Uridine Diphosphate; Uridine Triphosphate

2010
P2X2, P2X4 and P2Y1 receptors elevate intracellular Ca2+ in mouse embryonic stem cell-derived GABAergic neurons.
    British journal of pharmacology, 2009, Volume: 158, Issue:8

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cell Line; Embryonic Stem Cells; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Mice; Neurons; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; Uridine Diphosphate; Uridine Triphosphate; Zinc

2009
Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells.
    Reproductive biology and endocrinology : RB&E, 2010, Jul-14, Volume: 8

    Topics: Animals; Calcium; Cells, Cultured; Female; Gene Expression; Intracellular Space; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Theca Cells; Uridine Diphosphate; Uridine Triphosphate

2010
Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-30, Volume: 108, Issue:35

    Topics: Amino Acid Motifs; Catalysis; Evolution, Chemical; Hydrolysis; Pyrophosphatases; Uridine Diphosphate; Uridine Triphosphate

2011
Role of ecto-NTPDases on UDP-sensitive P2Y(6) receptor activation during osteogenic differentiation of primary bone marrow stromal cells from postmenopausal women.
    Journal of cellular physiology, 2012, Volume: 227, Issue:6

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adolescent; Adult; Aged; Alkaline Phosphatase; Antigens, CD; Apyrase; Bone Marrow Cells; Calcium; Calcium Signaling; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Middle Aged; Osteogenesis; Phenotype; Postmenopause; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Stromal Cells; Time Factors; Uridine Diphosphate; Uridine Triphosphate; Young Adult

2012
Alterations in vasoconstrictor responses to the endothelium-derived contracting factor uridine adenosine tetraphosphate are region specific in DOCA-salt hypertensive rats.
    Pharmacological research, 2012, Volume: 65, Issue:1

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Arteries; Basilar Artery; Desoxycorticosterone; Dinucleoside Phosphates; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Femoral Artery; Hypertension; Male; Mesenteric Arteries; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Sodium Chloride, Dietary; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasoconstrictor Agents

2012
Pharmacological characterization of uracil nucleotide-preferring P2Y receptors modulating intestinal motility: a study on mouse ileum.
    Purinergic signalling, 2012, Volume: 8, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Motility; Ileum; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Receptors, Purinergic P2; Uridine Diphosphate; Uridine Triphosphate

2012
P2Y receptors regulate proliferation of human pancreatic duct epithelial cells.
    Pancreas, 2012, Volume: 41, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blotting, Western; Boron Compounds; Cell Line, Tumor; Cell Proliferation; Deoxyadenine Nucleotides; Epithelial Cells; Estrenes; Gene Expression Regulation, Neoplastic; Humans; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Isothiocyanates; Maleimides; Pancreatic Ducts; Protein Kinase C; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiourea; Type C Phospholipases; Uridine Diphosphate; Uridine Triphosphate

2012
A Ca²⁺-dependent chloride current and Ca²⁺ influx via Ca(v)1.2 ion channels play major roles in P2Y receptor-mediated pulmonary vasoconstriction.
    British journal of pharmacology, 2012, Volume: 166, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calcium Channels, L-Type; Calcium Signaling; Chloride Channels; Endothelium, Vascular; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Membrane Transport Modulators; Myography; Pulmonary Artery; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X1; Receptors, Purinergic P2Y; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2012
Modulation of spontaneous activity in the overactive bladder: the role of P2Y agonists.
    American journal of physiology. Renal physiology, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Algorithms; Animals; Calcium Signaling; Data Interpretation, Statistical; Electric Stimulation; Electrophysiological Phenomena; Fluorescent Antibody Technique; Microscopy, Confocal; Mucous Membrane; Muscle Contraction; Muscle, Smooth, Vascular; Purinergic P2Y Receptor Agonists; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries; Uridine Diphosphate; Uridine Triphosphate; Urinary Bladder; Urinary Bladder, Overactive; Urothelium

2012
Evidence for the existence of pyrimidinergic transmission in rat brain.
    Neuropharmacology, 2015, Volume: 91

    Topics: Acetylcholine; Animals; Brain Chemistry; Choline; Corpus Striatum; Extracellular Fluid; Male; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y; Uridine; Uridine Diphosphate; Uridine Triphosphate

2015
Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Apoptosis; Cells, Cultured; Female; Host-Parasite Interactions; Macrophages; Macrophages, Peritoneal; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nitric Oxide; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P2Y; Suramin; Toxoplasma; Uridine Diphosphate; Uridine Triphosphate

2015
Cardiomyogenesis of embryonic stem cells upon purinergic receptor activation by ADP and ATP.
    Purinergic signalling, 2015, Volume: 11, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Differentiation; Embryonic Stem Cells; Female; Gene Expression; Membrane Potentials; Mice; Muscle Development; Myocardial Contraction; Myocytes, Cardiac; Pregnancy; Purinergic P2X Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Uridine Diphosphate; Uridine Triphosphate

2015
ATP release, generation and hydrolysis in exocrine pancreatic duct cells.
    Purinergic signalling, 2015, Volume: 11, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Bile Acids and Salts; Cell Line; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Osmolar Concentration; Pancreas, Exocrine; Pancreatic Ducts; Receptors, Purinergic P2X; Receptors, Purinergic P2Y; Stress, Physiological; Uridine Diphosphate; Uridine Triphosphate

2015
UDP/P2Y6 receptor signaling regulates IgE-dependent degranulation in human basophils.
    Allergology international : official journal of the Japanese Society of Allergology, 2017, Volume: 66, Issue:4

    Topics: Adult; Basophils; Calcium; Cell Degranulation; Cell Survival; Gene Expression; Healthy Volunteers; Humans; Immunoglobulin E; Isothiocyanates; Pyrophosphatases; Receptors, Purinergic P2; Signal Transduction; Thiourea; Uridine Diphosphate; Uridine Triphosphate; Young Adult

2017
N-Propyl-N'-2-pyridylurea-modified silica as mixed-mode stationary phase with moderate weak anion exchange capacity and pH-dependent surface charge reversal.
    Journal of chromatography. A, 2018, Jul-27, Volume: 1560

    Topics: Anion Exchange Resins; Anions; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pyridines; Silicon Dioxide; Surface Properties; Urea; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2018
P2Y
    Purinergic signalling, 2018, Volume: 14, Issue:4

    Topics: Adenosine Diphosphate; Calcium; Humans; Mesenchymal Stem Cells; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Uridine Diphosphate; Uridine Triphosphate

2018
Extracellular Uridine Nucleotides-Induced Contractions Were Increased in Femoral Arteries of Spontaneously Hypertensive Rats.
    Pharmacology, 2021, Volume: 106, Issue:7-8

    Topics: Animals; Endothelium, Vascular; Extracellular Space; Femoral Artery; Hypertension; Male; Peripheral Arterial Disease; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2021
Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel.
    Scientific reports, 2021, 08-20, Volume: 11, Issue:1

    Topics: Acute Disease; Adenosine Triphosphate; Animals; Antioxidants; Arrhythmias, Cardiac; Disease Models, Animal; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Rats, Wistar; Tachycardia; Uridine; Uridine Diphosphate; Uridine Triphosphate; Ventricular Fibrillation

2021
Characterisation of P2Y receptor subtypes mediating vasodilation and vasoconstriction of rat pulmonary artery using selective antagonists.
    Purinergic signalling, 2022, Volume: 18, Issue:4

    Topics: Adenosine Triphosphate; Animals; Diphosphates; Pulmonary Artery; Rats; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Uridine; Uridine Diphosphate; Uridine Triphosphate; Vasodilation

2022
Effects of uridine and nucleotides on hemostasis parameters.
    Journal of thrombosis and thrombolysis, 2023, Volume: 55, Issue:4

    Topics: Adenosine Triphosphate; Collagen; Humans; Nucleotides; Platelet Aggregation; Uridine; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2023