uridine has been researched along with phenyl acetate in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (69.53) | 18.7374 |
| 1990's | 2 (1.56) | 18.2507 |
| 2000's | 12 (9.38) | 29.6817 |
| 2010's | 21 (16.41) | 24.3611 |
| 2020's | 4 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Goodman, DB; Lien, EL; Rasmussen, H | 1 |
| Kostellow, AB; Morrill, GA; Poupko, JM | 1 |
| Bronzert, D; Huff, K; Kahn, CR; Lippman, ME; Monaco, ME; Osborne, CK | 1 |
| Isono, K; Suhadolnik, RJ | 1 |
| Isono, K; Uzawa, J | 1 |
| Gray, S; Lopez, I; Matthews, E; Melnykovych, G | 1 |
| Brun, G; Goodgame, DM; Skapski, AC | 1 |
| Bulla, LA; De Pinto, J; Nickerson, KW | 1 |
| Ryan, JM | 1 |
| D'Alessio, G; Di Donato, A; Donadio, S; Piccoli, R; Tamburrini, M | 1 |
| Iwasaki, K; Komiyama, K; Miura, M; Nozawa, Y; Umezawa, I; Yamamoto, H | 1 |
| Macgregor, HC | 1 |
| Chambers, TC; Wolanski, BS | 1 |
| Reutter, W; Reynolds, RD | 1 |
| Bolund, L; Gahrton, G; Killander, D; Rigler, R; Wahren, B | 1 |
| Archetti, I; Bereczky, E; Rosati-Valente, F; Steve-Bocciarelli, D | 1 |
| Ohman, R; Walther, B | 1 |
| Jezyk, PF; Liberti, JP | 1 |
| Kowal, J | 1 |
| Corbascio, AN; Ishii, DN | 1 |
| Kole, R; Shugar, D; Sierakowska, H | 1 |
| Rubin, H | 1 |
| Formoso, C | 1 |
| Birchall, K; Halkerston, ID | 1 |
| Honda, A; Morioka, S; Otsuka, E; Shigyo, H; Sugiyama, T | 1 |
| Hall, RH; Monahan, JJ | 1 |
| Barbey, S; Despres, S; Nezelof, C; Rousseau, MF | 1 |
| Stjernholm, RL; Warren, KS | 1 |
| Atkins, LM; Gadsden, RH; Gale, GR; Walker, EM | 1 |
| Bernstein, R; Cohen, MM; Mukherjee, AB; Waite, RG | 1 |
| McLellan, WL; Vogel, HJ | 1 |
| Iitaka, Y; Morikawa, K; Nishimura, S; Torii, K; Tsuboi, M | 1 |
| Beebe, JL | 1 |
| Cashman, TM; Chou, SC; Conklin, KA | 1 |
| Ivanovics, GA; Robins, RK; Rousseau, RJ; Wilson, HR | 1 |
| Sutherland, RM; Whitney, RB | 1 |
| Clark, HF; György, E; Sokol, F; Tomassini, N | 1 |
| Hayes, SJ; Lis, AW | 1 |
| Saenger, W; Suck, D | 1 |
| Brandt, EJ; MacGillivray, MH | 1 |
| Naimy, NK; Scribner, JD | 1 |
| Baker, J; Jarman, M; Stock, JA | 1 |
| Koshihara, H; Yukawa, O | 1 |
| Beliaev, SD; Kolomiĭtseva, IK; Kuzin, AM; Strazhevskaia, NB; Struchkov, VA | 1 |
| Benjamin, W; Gellhorn, A | 1 |
| Mizuno, S; Shirahata, S; Tano, S | 1 |
| Harada, F; Murao, K; Nishimura, S; Saneyoshi, M | 1 |
| Lin, FH; Thormar, H | 1 |
| Hiasa, Y; Ito, N; Konishi, Y; Sugihara, R; Yasuzumi, G | 1 |
| Rajabalee, FJ | 1 |
| Chou, SC; Conklin, KA; Heu, P; Ramanathan, S | 1 |
| Hashimoto, Y; Oshima, H; Yuki, H | 1 |
| Dawson, KM | 1 |
| Oberhausen-Braun, H | 1 |
| Franke, HD | 1 |
| Bertermann, H; Kusche, B; Schirmer, A | 1 |
| Lawrence, S; Trachewsky, D | 1 |
| Hotta, S; Yoshinaka, Y | 1 |
| Elis, J; Jankú, I; Rasková, H | 1 |
| Burrell, AD; Dean, CJ; Feldschreiber, P | 1 |
| Bensch, KG; Creasey, WA; Malawista, SE | 1 |
| Allfrey, VG; Mirsky, AE; Pogo, BG | 1 |
| Borek, E; Srinivasan, PR | 1 |
| Allfrey, VG; Pogo, AO; Pogo, BG | 1 |
| Nakao, K; Ono, T; Takaku, F; Terayama, H | 1 |
| Falor, WH; Stjernholm, RL | 1 |
| MacGillivray, AJ; Monjardino, JP | 1 |
| Carty, RP; Pincus, M | 1 |
| Ledinko, N | 1 |
| Estrada, S; Gomez-Lojero, C | 1 |
| Ishikawa, H; Newburgh, RW | 1 |
| Allfrey, VG; Gershey, EL; Littau, VC; Mirsky, AE; Pogo, BG | 1 |
| Bollack, C; Ebel, JP | 1 |
| Johnston, GA | 1 |
| Pogo, BG | 1 |
| Creasey, WA | 1 |
| Batt, RD; Thomas, TD | 1 |
| Keup, U; Schneider, F; Seeber, S | 1 |
| Alfert, M; Das, NK | 1 |
| Bolund, L; Darzynkiewicz, Z; Ringertz, NR | 1 |
| Itoh, T; Mizuno, Y; Tagawa, H | 1 |
| Brown, EG; Mangat, BS | 1 |
| Romano, AH; Sjogren, RE | 1 |
| Ellgaard, EG | 1 |
| Cameron, CM; Rillema, JA | 2 |
| Chou, SC; Hokama, Y; Okano, CK | 1 |
| Allegra, JC; Lippman, ME | 1 |
| Bertino, J; Kelsen, DP; Martin, D; O'Neil, J; Saltz, L; Schwartz, G; Sung, MT; von Borstel, R | 1 |
| Bartlett, MG; Teng, Q; Tumbula, DL; Whitman, WB | 1 |
| Campbell, E; Davidson, K; Diab, SG; Drengler, RL; Eckhardt, SG; Garner, AM; Hammond, LA; Hidalgo, M; Louie, A; O'Neil, JD; Rodriguez, G; Rowinsky, EK; Villalona-Calero, MA; von Borstel, R; Von Hoff, DD; Weiss, G | 1 |
| Al Safarjalani, ON; Ashour, OM; el Kouni, MH; Naguib, FN; Panzica, RP | 1 |
| Ashour, OM; el Kouni, MH; Goudgaon, NM; Naguib, FN; Schinazi, RF | 1 |
| Barbe, J; Castilla, JJ; Mesa, C; Moraleda-Lindez, V; Osuna, A; Rodriguez-Cabezas, N; Sanchez-Moreno, M | 1 |
| DAVIDSON, EA; OLAVESEN, AH | 1 |
| Garcia, RA; Hu, Z; Li, D; Liu, LS; Saydoff, JA; von Borstel, RW | 1 |
| Beal, MF; Browne, SE; Calingasan, NY; Gardian, G; Klivenyi, P; Saydoff, J; von Borstel, R; Yang, L | 1 |
| Saif, MW; von Borstel, R | 1 |
| Garcia, RA; Gonzalez, A; Hu, Z; Liu, L; Saydoff, JA; von Borstel, RW | 1 |
| Kemeny, NE; Leonard, GD | 1 |
| Abbruzzese, JL; Cobb, PW; Doroshow, JH; Issell, BF; Macdonald, JS; McCoy, S; Patel, T; Yost, KJ | 1 |
| Beal, MF; Brenneman, D; Browne, SE; Burr, H; Cardin, S; Garcia, RA; Gonzalez, A; Gregorio, J; Hu, Z; Liu, L; Saydoff, JA; Sheng, J; von Borstel, RW | 1 |
| Bolo, NR; Cohen, BM; Daniels, M; Haws, C; Jensen, JE; Lyoo, IK; Renshaw, PF; Rusche, JR; Stoll, AL; Yoon, SJ | 1 |
| Cheung, P; Jacob, P; Mulligan, K; Roman, MC; Schambelan, M; Walker, UA; Weinberg, ME; Wen, M | 1 |
| Ferreira, ML; Gudiño, ED; Iglesias, LE | 1 |
| Garcia, R; Hu, Z; Li, Q; Olariu, A; Pei, J; Saydoff, JA; Sheng, J; Sun, GY; von Borstel, R | 1 |
| Traynor, K | 1 |
| Diasio, RB; Saif, MW | 1 |
| Bai, G; Beaver, JA; Charlab, R; Chen, XH; Cheng, J; Dinin, J; Dorff, SE; Ibrahim, A; Ison, G; Jin, R; Kim, G; Liu, Q; Marathe, A; McGuinn, WD; McKee, AE; Palmby, TR; Pazdur, R; Pierce, W; Sridhara, R; Stephens, O; Tang, S; Wang, Y; Ysern, X | 1 |
| Bamat, MK; Cartwright, TH; El-Rayes, BF; Fakih, MG; King, TR; Ma, WW; Posey, JA; Saif, MW; von Borstel, RW | 1 |
| Wilkinson, E | 1 |
| Galuski, K; Gil, B; Nugent, FW; Vaudo, CE; Zarwan, C | 1 |
| Geller, RJ; Morgan, BW; Santos, C | 1 |
| Cisterna, B; Costanzo, M; Malatesta, M; Mannina, L; Sobolev, AP; Zancanaro, C | 1 |
| Hall, AJ; Holdsworth, CI; Lettieri, S; Lim, KF | 1 |
| Duffy, AP; Hausner, PF; Oliver, WD | 1 |
| Hu, EH; Keung, YK; Yu, D; Zurayk, M | 1 |
| Aglietta, M; Bonzano, A; Cagnazzo, C; Depetris, I; Filippi, R; Leone, F; Marino, D | 1 |
| Bamat, MK; Garcia, RAG; Saydoff, JA; von Borstel, RW | 1 |
| Brutcher, E; Christensen, D; Hennessey Smith, M; Koutlas, JB; Sellers, JB; Thompson, J; Timmons, T | 1 |
| Berrío Escobar, JF; Castelli, F; Giordani, C; Márquez Fernández, DM; Sarpietro, MG | 1 |
| Robert, J | 1 |
| Amylidi, AL; Angelaki, A; Aravantinos, G; Boumpoucheropoulos, S; Fildissis, G; Lampropoulou, DI; Laschos, K; Nanou, E; Nasioulas, G; Papadopoulou, E; Soupos, N; Zidianakis, V | 1 |
| Badea, A; Garcia, E; Gintjee, TJ; Goodnough, R; Li, K; Lynch, KL; Repplinger, D | 1 |
| Ali, S; Bui, J; Frederick, A; Garg, A; Haas, R; Nguyen, L; Sahagian, M; Sherer, K | 1 |
| Leung, M; Rogers, JE; Shureiqi, I | 1 |
8 review(s) available for uridine and phenyl acetate
| Article | Year |
|---|---|
Fatty acid biosynthesis and RNA function in fasting, aging and diabetes.
Topics: Acetates; Adipose Tissue; Aging; Alkenes; Animals; Biological Transport; Blood Glucose; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Diabetes Mellitus, Experimental; Diet Therapy; Fasting; Fatty Acids; Glucose; In Vitro Techniques; Insulin; Lipids; Liver Glycogen; Male; Microsomes; Nucleotides; Oleic Acids; Phosphates; Phosphorus Isotopes; Puromycin; Rats; RNA; RNA, Messenger; Stearic Acids; Tritium; Uridine | 1966 |
Enzymatic alteration of macromolecular structure.
Topics: Acetates; Alkylation; Amino Acids; Coliphages; Collagen; Escherichia coli; Hypoxanthines; Nucleic Acids; Proteins; RNA, Transfer; Uridine | 1966 |
FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs.
Topics: Acetates; Animals; Antineoplastic Agents; Capecitabine; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; Fluorouracil; Humans; Neoplasms; Prescription Drug Overuse; Research Design; Treatment Outcome; United States; United States Food and Drug Administration; Uridine | 2016 |
Successful use of uridine triacetate (Vistogard) three weeks after capecitabine in a patient with homozygous dihydropyrimidine dehydrogenase mutation: A case report and review of the literature.
Topics: Acetates; Antidotes; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Female; Humans; Middle Aged; Mutation; Uridine | 2019 |
Fluoropyrimidine-induced cardiotoxicity.
Topics: Acetates; Capecitabine; Cardiotoxicity; Cardiovascular Diseases; Drug Combinations; Fluorouracil; Humans; Neoplasms; Pyrimidines; Pyrrolidines; Quinazolines; Thiophenes; Thymine; Trifluridine; Uracil; Uridine | 2018 |
5-Fluorouracil and Capecitabine: Assessment and Treatment of Uncommon Early-Onset Severe Toxicities Associated With Administration.
Topics: Acetates; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Patient Safety; Risk Assessment; Severity of Illness Index; Survival Analysis; Uridine | 2018 |
Fluoropyrimidine-induced toxicity and DPD deficiency.. A case report of early onset, lethal capecitabine-induced toxicity and mini review of the literature. Uridine triacetate: Efficacy and safety as an antidote. Is it accessible outside USA?
Topics: Acetates; Aged; Antidotes; Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Female; Humans; Neoplasms; Uridine | 2020 |
Triacetyluridine treats epileptic encephalopathy from CAD mutations: a case report and review.
Topics: Acetates; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Child; Dihydroorotase; Epilepsy, Generalized; Female; Humans; Mutation, Missense; Uridine | 2021 |
5 trial(s) available for uridine and phenyl acetate
| Article | Year |
|---|---|
Phase I trial of PN401, an oral prodrug of uridine, to prevent toxicity from fluorouracil in patients with advanced cancer.
Topics: Acetates; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Prodrugs; Uridine | 1997 |
Phase I and pharmacologic study of PN401 and fluorouracil in patients with advanced solid malignancies.
Topics: Acetates; Adult; Antimetabolites, Antineoplastic; Cytoprotection; Diarrhea; Dose-Response Relationship, Drug; Female; Fluorouracil; Hematologic Diseases; Humans; Male; Maximum Tolerated Dose; Neutropenia; Prodrugs; Statistics, Nonparametric; Uridine | 2000 |
Phase II trial of PN401, 5-FU, and leucovorin in unresectable or metastatic adenocarcinoma of the stomach: a Southwest Oncology Group study.
Topics: Acetates; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Stomach Neoplasms; Survival Analysis; Uridine | 2006 |
Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients.
Topics: Acetates; Adult; Antidepressive Agents; Bipolar Disorder; Brain Chemistry; Depressive Disorder; Female; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Neuropsychological Tests; Phosphocreatine; Psychiatric Status Rating Scales; Uridine | 2008 |
Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement.
Topics: Acetates; Adult; Biological Availability; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Male; Middle Aged; Models, Biological; Osmolar Concentration; Up-Regulation; Uridine; Young Adult | 2011 |
115 other study(ies) available for uridine and phenyl acetate
| Article | Year |
|---|---|
Effects of an acetyl-coenzyme A carboxylase inhibitor and a sodium-sparing diuretic on aldosterone-stimulated sodium transport, lipid synthesis, and phospholipid fatty acid composition in the toad urinary bladder.
Topics: Acetates; Acetyl-CoA Carboxylase; Aldosterone; Amiloride; Animals; Biological Transport, Active; Bufo marinus; Fatty Acids; Female; Leucine; Ligases; Lipids; Nafenopin; Phospholipids; Propionates; Protein Biosynthesis; Pyrazines; RNA; Sodium; Uridine; Urinary Bladder | 1975 |
Histone acetylation associated with gastrulation in Rana pipiens.
Topics: Acetates; Acetylation; Acetyltransferases; Animals; Anura; Chromatin; Cycloheximide; Genes; Germ Layers; Histones; In Vitro Techniques; Lysine; Nucleoproteins; Rana pipiens; Uridine | 1977 |
Direct inhibition of growth and antagonism of insulin action by glucocorticoids in human breast cancer cells in culture.
Topics: Acetates; Breast Neoplasms; Cell Division; Cells, Cultured; Dexamethasone; Female; Glucocorticoids; Humans; Insulin Antagonists; Receptor, Insulin; Thymidine; Thymidine Kinase; Uridine | 1979 |
Biosynthesis of the C-nucleoside, minimycin: asymmetric incorporation of glutamate and acetate into the oxazine ring.
Topics: Acetates; Anti-Bacterial Agents; Carbon Radioisotopes; Glutamates; Oxazines; Streptomyces; Tritium; Uridine | 1977 |
13C-NMR evidence for the biosynthetic incorporation of acetate into minimycin and compounds related to Krebs cycle.
Topics: Acetates; Anti-Bacterial Agents; Bacterial Proteins; Carbon Isotopes; Carbon Radioisotopes; Citric Acid Cycle; Glutamates; Isotope Labeling; Magnetic Resonance Spectroscopy; Streptomyces; Succinates; Uridine | 1977 |
Inhibition of cholesterol biosynthesis in HeLa cells by glucocorticoids.
Topics: Acetates; Cholesterol; Culture Media; Dexamethasone; Glucocorticoids; HeLa Cells; Kinetics; Leucine; Mevalonic Acid; Protein Biosynthesis; Transcription, Genetic; Uridine | 1976 |
Reaction of ribonucleosides and deoxynucleosides with copper(II) acetate.
Topics: Acetates; Chemical Phenomena; Chemistry; Copper; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Ribonucleosides; Spectrum Analysis; Thymidine; Uridine | 1975 |
Lipid metabolism during bacterial growth, sporulation, and germination: kinetics of fatty acid and macromolecular synthesis during spore germination and outgrowth of Bacillus thuringiensis.
Topics: Acetates; Bacillus; Bacterial Proteins; Carbon Dioxide; Carbon Radioisotopes; Cell Division; DNA, Bacterial; Fatty Acids; Glutamates; Glycerol; Kinetics; Lipid Metabolism; Phenylalanine; RNA, Bacterial; Spores, Bacterial; Thymidine; Time Factors; Tritium; Uridine | 1975 |
Alterations in chromatin functions during aging in vitro.
Topics: Acetates; Acetylation; Adenosine Monophosphate; Carbon Radioisotopes; Cell Biology; Cell Line; Cell Survival; Chromatin; Histones; Humans; In Vitro Techniques; Lung; Mitosis; RNA; Transcription, Genetic; Tritium; Uridine | 1975 |
Site-directed alkylation and site-site interactions in bovine seminal ribonuclease.
Topics: Acetates; Alkylation; Animals; Binding Sites; Cattle; Histidine; Hydroxyprostaglandin Dehydrogenases; Kinetics; Male; Pancreas; Ribonucleases; Seminal Vesicles; Uridine | 1986 |
Mechanism of action of antitumor antibiotic stubomycin.
Topics: Acetates; Acetic Acid; Antibiotics, Antineoplastic; Polyenes; Saccharomyces cerevisiae; Uridine | 1985 |
Pattern of incorporation of (3H)uridine into RNA of amphibian oocyte nucleoli.
Topics: Acetates; Animals; Autoradiography; Cell Nucleolus; Chromosomes; DNA; Female; Histocytochemistry; Methods; Microscopy, Electron; Nucleoproteins; Ovum; Quaternary Ammonium Compounds; RNA; Staining and Labeling; Time Factors; Tritium; Uridine; Urodela | 1967 |
The multiplication of lettuce necrotic yellows virus.
Topics: Acetates; Autoradiography; Cell Nucleus; Citrates; Cytoplasm; Dactinomycin; Lead; Microscopy, Electron; Nicotiana; Plant Viruses; Plants, Edible; Plants, Toxic; Staining and Labeling; Time Factors; Tritium; Uranium; Uridine; Viral Proteins; Virus Replication | 1971 |
Inhibition of induction of rat liver tyrosine aminotransferase by D-galactosamine.
Topics: Acetates; Animals; Butyrates; Cyclic AMP; Dexamethasone; Enzyme Induction; Galactosamine; Galactose; Glucagon; Glucosamine; Glucose; Hexosamines; Kinetics; Liver; Male; Rats; Tyrosine Transaminase; Uracil Nucleotides; Uridine; Uridine Diphosphate Sugars | 1973 |
Structural changes in the deoxyribonucleoprotein (DNP) complex of leukocytes from patients with infectious mononucleosis.
Topics: Acetates; Acridines; Adolescent; Adult; Blood Proteins; Culture Techniques; DNA; Female; Fluorometry; Histocytochemistry; Humans; Infectious Mononucleosis; Leukocytes; Male; Middle Aged; Nucleoproteins; Protein Binding; Pyridines; RNA; Staining and Labeling; Tritium; Uridine | 1970 |
Elongated structures present in cells infected with influenza viruses.
Topics: Acetates; Aldehydes; Animals; Antibodies; Autoradiography; Cell Nucleus; Chick Embryo; Culture Techniques; Extraembryonic Membranes; Ferritins; Haplorhini; Hydrogen Peroxide; Kidney; Lead Poisoning; Microscopy, Electron; Orthomyxoviridae; Osmium; Oxides; RNA, Viral; Staining and Labeling; Tritium; Uranium; Uridine | 1970 |
Cell layer assay.
Topics: Acetates; Animals; Carbon Radioisotopes; Cell Aggregation; Cell Line; Chelating Agents; Cricetinae; Culture Techniques; Edetic Acid; Kidney; Kinetics; Leucine; Palmitic Acids; Phosphorus Radioisotopes; Thymidine; Tritium; Uridine | 1974 |
Metabolic activities of mechanically and enzymatically prepared rat liver cells.
Topics: Acetates; Animals; Carbon Dioxide; Carbon Isotopes; Hyaluronoglucosaminidase; Isoleucine; Kinetics; Lipids; Liver; Male; Methods; Microbial Collagenase; Oxygen Consumption; Palmitic Acids; Rats; RNA; Tritium; Uridine | 1969 |
Adrenal cells in tissue culture. VII. The effect of inhibitors of protein synthesis on steroidogenesis and glycolysis.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Glycolysis; Leucine; Lysine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1970 |
Some metabolic effects of halothane on mammalian tissue culture cells in vitro.
Topics: Acetates; Animals; Autoradiography; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Fatty Acids; Halothane; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phospholipids; Protein Biosynthesis; Rats; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1971 |
A ribonuclease substrate resistant to phosphodiesterase II: 5'-O-benzyluridine-3'-(alpha-naphthylphosphate).
Topics: Acetates; Benzyl Compounds; Chemical Phenomena; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Coliphages; Naphthalenes; Pancreas; Phosphoric Monoester Hydrolases; Pyrans; Pyridinium Compounds; Ribonucleases; Spleen; Uridine | 1971 |
Inhibition of DNA synthesis in animal cells by ethylene diamine tetraacetate, and its reversal by zinc.
Topics: Acetates; Animals; Avian Sarcoma Viruses; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; DNA; Edetic Acid; Glycols; Kinetics; Leucine; Protein Biosynthesis; RNA; Thymidine; Time Factors; Tritium; Uridine; Zinc | 1972 |
Circular dichroism study of the effects of magnesium perchlorate and temperature on the solution conformation of uridine 5'-monophosphate, uridine 3'-monophosphate, uridine, and uridylyl-(3' leads to 5')-uridine.
Topics: Acetates; Circular Dichroism; Magnesium; Magnetic Resonance Spectroscopy; Molecular Conformation; Perchlorates; Temperature; Ultraviolet Rays; Uracil Nucleotides; Uridine | 1972 |
Effect of antihistamines on ribonucleic acid synthesis in the uterus of the ovariectomized rat.
Topics: Acetates; Adrenal Glands; Animals; Castration; Depression, Chemical; Diphenhydramine; Female; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Intestine, Small; Phenylalanine; Protein Biosynthesis; Rats; RNA; Tritium; Uridine; Uterus | 1969 |
Studies on transfer ribonucleic acids and related compounds. 8(1). Further studies on aromatic phosphoramidates as a protecting group for phosphomonoesters.
Topics: Acetates; Amides; Anilides; Benzoates; Binding Sites; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Dicyclohexylcarbodiimide; Drug Stability; Electrophoresis, Paper; Half-Life; Hydrogen-Ion Concentration; Kinetics; Nucleic Acid Conformation; Organophosphates; Organophosphorus Compounds; Pyridines; RNA, Transfer; Spectrophotometry, Ultraviolet; Time Factors; Uridine | 1974 |
Magnesium acetate treatment of roller bottles for the preparation of uniform cell monolayers.
Topics: Acetates; Carcinoma; Cell Adhesion; Cell Line; Culture Techniques; Evaluation Studies as Topic; Glass; HeLa Cells; Leucine; Magnesium; Methods; Mouth Neoplasms; Phosphates; Phosphorus Radioisotopes; Tritium; Uridine | 1974 |
[Histocytosis-X. Histochemical and autoradiographic elements proving lipid synthesis in in vitro culture].
Topics: Acetates; Autoradiography; Carbon Radioisotopes; Cell Membrane; Choline; Culture Techniques; Eosinophilic Granuloma; Esterases; Fibroblasts; Glycerol; Glycine; Histiocytes; Histocytochemistry; Humans; Leucyl Aminopeptidase; Lipids; Lymphatic Diseases; Mevalonic Acid; Palmitates; Serine; Thymidine; Tritium; Uridine | 1974 |
Schistosoma mansoni: utilization of exogenous metabolites by eggs in vitro.
Topics: Acetates; Animals; Arginine; Autoradiography; Butyrates; Carbon Radioisotopes; Culture Media; DNA; Female; Glucose; Glycine; In Vitro Techniques; Isoleucine; Lactates; Lipids; Liver; Mice; Microscopy, Electron; Ovum; Parasite Egg Count; Protein Biosynthesis; RNA; Schistosoma mansoni; Schistosomiasis; Thymidine; Uridine | 1974 |
Some effects of 2,4-D and 2,4,5-T on Ehrlich ascites tumor cells in vivo and in vitro.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Culture Techniques; Depression, Chemical; DNA; Guanine Nucleotides; Herbicides; Mice; Mice, Inbred Strains; Phenols; RNA; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Incorporation of uridine- 3 H and sodium acetate- 14 C in lymphocytes derived from normal and leukemic individuals.
Topics: Acetates; Acetylation; Autoradiography; Carbon Isotopes; Cell Nucleus; Cells, Cultured; Culture Media; Histones; Humans; Lectins; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocytes; RNA; RNA, Neoplasm; Sodium; Tritium; Uridine | 1972 |
Stability of argECBH messenger RNA under arginine excess or restriction.
Topics: Acetates; Arginine; Escherichia coli; Half-Life; Kinetics; Nucleic Acid Hybridization; Ornithine; Rifampin; RNA, Messenger; Tritium; Uridine | 1973 |
Crystal and molecular structure of the methyl ester of uridin-5-oxyacetic acid: a minor constituent of Escherichia coli tRNAs.
Topics: Acetates; Anticodon; Crystallography; Escherichia coli; Keto Acids; Models, Molecular; Molecular Conformation; Molecular Weight; RNA, Bacterial; RNA, Transfer; Uridine; X-Ray Diffraction | 1974 |
Transport alterations in a phosphatidylethanolamine-deficient mutant of Bacillus subtilis.
Topics: Acetates; Adenosine; Amino Acids; Aspartic Acid; Bacillus subtilis; Biological Transport, Active; Carbon Isotopes; Cell Membrane; Culture Media; Genetics, Microbial; Glucose; Lysine; Mutation; Phosphatidylethanolamines; Pyruvates; Stereoisomerism; Thymine; Time Factors; Uracil; Uridine | 1972 |
The effect of emetine on macromolecular synthesis in synchronized tetrahymena pyriformis.
Topics: Acetates; Amino Acids; Animals; Carbon Isotopes; Cell Division; Emetine; Macromolecular Substances; Protein Biosynthesis; Tetrahymena pyriformis; Thymidine; Uridine | 1972 |
Nucleoside peptides. 5. Synthesis of certain N-(5-uridineacetyl)amino acids from 5-uridineacetic acid.
Topics: Acetates; Bacillus subtilis; Enterococcus faecalis; Escherichia coli; Microbial Sensitivity Tests; Peptide Biosynthesis; Peptides; Phenylalanine; Pseudomonas aeruginosa; Serratia marcescens; Staphylococcus; Structure-Activity Relationship; Uridine | 1973 |
Requirement for calcium ions in lymphocyte transformation stimulated by phytohemagglutinin.
Topics: Acetates; Calcium; Chelating Agents; DNA; Edetic Acid; Humans; Lectins; Lymphocyte Activation; Methods; RNA; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Heterogeneity in the phospholipid content of purified rabies virus (ERA strain) particles.
Topics: Acetates; Amino Acids; Animals; Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, Gel; Cricetinae; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Kidney; Microscopy, Electron; Phospholipids; Phosphorus Isotopes; Rabies virus; RNA, Viral; Sucrose; Tritium; Uridine; Viral Proteins; Virus Cultivation; Zinc | 1972 |
Studies on 5-hydroxyuridine (isobarbituridine): VIII. Instability in partition chromatography solvent ethylacetate-1-butanol-ligroin-water.
Topics: Acetates; Butanols; Candida; Chromatography; Drug Stability; Ethanol; RNA, Bacterial; RNA, Ribosomal; Snake Venoms; Solvents; Uridine | 1972 |
The relationship between hydrogen bonding and base stacking in crystalline 4-thiouridine derivatives.
Topics: Acetates; Arabinose; Binding Sites; Chemical Phenomena; Chemistry; Hydrogen; Methylthiouracil; Oxygen; RNA, Transfer; Sulfides; Thiouracil; Thiouridine; Thymidine; Uridine; X-Ray Diffraction | 1973 |
14 C-acetate incorporation and nucleic acid synthesis in human lymphocytes stimulated by PHA and tuberculin in vitro.
Topics: Acetates; Carbon Isotopes; Cell Membrane Permeability; Culture Techniques; DNA; Histones; Lectins; Lymphocytes; RNA; Templates, Genetic; Thymidine; Tritium; Tuberculin; Uridine | 1973 |
Reactions of esters of N-hydroxy-2-acetamidophenanthrene with cellular nucleophiles and the formation of free radicals upon decomposition of N-acetoxy-N-arylacetamides.
Topics: Acetamides; Acetates; Carbon Isotopes; Chemical Phenomena; Chemistry; Cytidine; Esters; Free Radicals; Guanosine; Hydrazines; Hydroxamic Acids; Magnetic Resonance Spectroscopy; Methionine; Methods; Phenanthrenes; Picrates; Ribonucleosides; Sulfates; Sulfides; Sulfuric Acids; Thymidine; Uridine | 1973 |
Synthesis of 2'- and 3'-O-acyluridines.
Topics: Acetates; Acylation; Benzyl Compounds; Methods; Oligonucleotides; Uridine | 1973 |
Acetylation of proteins in the course of sea urchin development.
Topics: Acetates; Acetylation; Animals; Carbon Radioisotopes; Lysine; Peptide Biosynthesis; Proteins; Puromycin; Sea Urchins; Tritium; Uridine; Valine | 1973 |
[Lipids in a high molecular weight complex of rat thymus and liver DNA].
Topics: Acetates; Animals; Carbon Radioisotopes; Cholesterol; DNA; Fatty Acids, Nonesterified; In Vitro Techniques; Lipids; Liver; Male; Phospholipids; Rats; Thymidine; Thymus Gland; Triglycerides; Uridine | 1974 |
Detection of an organ-specific population of RNA in the salmon brain.
Topics: Acetates; Aluminum Silicates; Animals; Brain; Centrifugation, Density Gradient; Deoxyribonucleases; DNA; Escherichia coli; Heart; Liver; Orotic Acid; Quinolines; Ribonucleases; RNA; Salmonidae; Sucrose; Tritium; Uridine | 1969 |
Uridin-5-oxy acetic acid: a new minor constituent from E. coli valine transfer RNA I.
Topics: Acetates; Chromatography, Thin Layer; Electrophoresis; Escherichia coli; Genetic Code; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nucleosides; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Ultraviolet Rays; Uridine; Valine | 1970 |
On visna virus: purification and nucleic acid content.
Topics: Acetates; Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chemical Precipitation; Choroid Plexus; Culture Techniques; Cytopathogenic Effect, Viral; Dialysis; Methods; Prions; RNA, Viral; Sheep; Sucrose; Thymidine; Tritium; Uridine; Zinc | 1970 |
Fine structure of nuclei as revealed by electron microscopy. VII. Hyperplastic liver nodules in rat induced by 3'-methyl-4-dimethylaminoazobenzene, 2-fluorenylacetamide and DL-ethionine.
Topics: Acetates; Animals; Autoradiography; Cell Nucleolus; Cell Nucleus; Chemical and Drug Induced Liver Injury; DNA; Ethionine; Fluorenes; Hyperplasia; Liver; Male; Microscopy, Electron; p-Dimethylaminoazobenzene; Rats; RNA; Tritium; Uridine | 1970 |
A convenient synthesis of 2',3',5'-tri-O-acetyladenosine and -uridine.
Topics: Acetates; Methods; Nucleosides; Uridine | 1971 |
Chlorpromazine effects on macromolecular syntheses in synchronized tetrahymena.
Topics: Acetates; Amino Acids; Animals; Carbon Isotopes; Cell Division; Chlorpromazine; DNA; Hot Temperature; Kinetics; Lipids; Protein Biosynthesis; RNA; Tetrahymena pyriformis; Thymidine; Time Factors; Tritium; Uridine | 1971 |
Metaphase-arresting action of carcinostatic tenuazonic acid.
Topics: Acetates; Animals; Antineoplastic Agents; Cells, Cultured; Colchicine; DNA, Neoplasm; Leucine; Mitosis; Neoplasm Proteins; Neoplasm Transplantation; Pyrrolidinones; Rats; Rats, Inbred Strains; RNA, Neoplasm; Sarcoma, Yoshida; Thymidine; Tritium; Uridine | 1972 |
Time course of the effect of AAF on mouse liver nucleic acid synthesis and its modification by inhibitors.
Topics: Acetates; Animals; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA; Fluorenes; Hydroxyurea; Leucine; Liver; Male; Mice; Orotic Acid; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; RNA, Ribosomal; RNA, Transfer; Thymidine; Time Factors; Tritium; Uridine; Urinary Bladder | 1972 |
[Experimental findings in animals concerning radiation sensitization in partial and whole body irradiation].
Topics: Acetates; Animals; Antibiotics, Antineoplastic; Dogs; Fluorouracil; Glyoxylates; Hydrazines; Hydroquinones; Hydroxymercuribenzoates; Iron; Maleimides; Mice; Oxygen; Procarbazine; Radiation Effects; Radiation-Sensitizing Agents; Rats; Uridine; Vitamin K | 1972 |
[Use of radiation sensitizing agents in radiotherapy].
Topics: Acetates; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Choline; Cysteine; Fluorouracil; Hematoporphyrins; Humans; Hydrogen Peroxide; Mitosis; Nitrogen Oxides; Oxygen; Periodicity; Quinones; Radiation-Sensitizing Agents; Radiotherapy; Steroids; Thyroid Hormones; Trypan Blue; Urethane; Uridine; Vitamins | 1972 |
CO 2 production from 14 C -labelled substrates by isolated kidney cells.
Topics: Acetates; Animals; Carbon Dioxide; Carbon Isotopes; Glucose; Glutamates; Kidney; Lactates; Malates; Oleic Acids; Oxidation-Reduction; Palmitic Acids; Propionates; Pyruvates; Uridine | 1972 |
Aldosterone-induced alterations in the synthesis of renal cortical chromatin components and acetylation of histones.
Topics: Acetates; Acylation; Adrenal Glands; Adrenalectomy; Aldosterone; Amino Acids; Animals; Carbon Isotopes; Chromatin; Histones; Kidney; Kinetics; Male; Protein Biosynthesis; Rats; RNA; Tritium; Uridine | 1972 |
Infectivity of virus-specific RNA's of a group A arbovirus, Chikungunya.
Topics: Acetates; Animals; Cell Line; Centrifugation, Density Gradient; Chemical Precipitation; Chikungunya virus; Chromatography, Gel; Cricetinae; Dextrans; Ethylamines; Kidney; Phenols; Ribonucleases; RNA, Viral; Sodium; Sucrose; Sulfates; Tritium; Uridine; Zinc | 1971 |
Time-response curves in the evaluation of the clinical efficacy of drugs.
Topics: Acetates; Administration, Oral; Antimetabolites; Azauridine; Evaluation Studies as Topic; Humans; Models, Biological; Psoriasis; Time Factors; Uridine | 1971 |
DNA-membrane association and the repair of double breaks in x-irradiated Micrococcus radiodurans.
Topics: Acetates; Carbon Isotopes; Cell Membrane; Centrifugation, Density Gradient; DNA Repair; DNA, Bacterial; Kinetics; Leucine; Methionine; Micrococcus; Molecular Weight; Protein Binding; Radiation Dosage; Radiation Effects; Streptomyces; Thymidine; Tritium; Uridine | 1971 |
Colchicine, vinblastine and griseofulvin. Pharmacological studies with human leukocytes.
Topics: Acetates; Alkaloids; Blood Proteins; Carbon Isotopes; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Cell-Free System; Chromatography, Gel; Chromatography, Thin Layer; Colchicine; Cytoplasm; Depression, Chemical; Drug Interactions; Glutamates; Griseofulvin; Humans; In Vitro Techniques; Inclusion Bodies; Kinetics; Leukocytes; Lipids; Lysosomes; Microscopy, Electron; Microtubules; Nucleic Acids; Protein Binding; RNA; Thymidine; Tritium; Uridine; Valine; Vinblastine; Vincristine | 1971 |
RNA synthesis and histone acetylation during the course of gene activation in lymphocytes.
Topics: Acetates; Alanine; Animals; Culture Techniques; Histones; Horses; Humans; Lectins; Lymphocytes; Molecular Biology; Puromycin; RNA; Uridine | 1966 |
Histone acetylation and RNA synthesis in rat liver regeneration.
Topics: Acetates; Animals; Carbon Isotopes; Chromosomes; Hepatectomy; Histones; Kinetics; Liver; Liver Regeneration; Lysine; Male; Rats; RNA; RNA Nucleotidyltransferases; Templates, Genetic; Time Factors; Tritium; Uridine | 1969 |
Changes in histone acetylation and RNA synthesis in the spleen of polycythemic mouse after erythropoietin injection.
Topics: Acetates; Anemia, Aplastic; Animals; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Nucleus; Erythrocytes; Erythropoietin; Female; Hematopoiesis; Histones; Mice; Polycythemia; RNA; Spleen; Stimulation, Chemical; Time Factors; Tritium; Uridine | 1969 |
Early biochemical changes in phytohemagglutinin-stimulated human lymphocytes of blood and lymph.
Topics: Acetates; Carbon Isotopes; Citric Acid Cycle; DNA; Glucose; Humans; Isoleucine; Lectins; Leucine; Leukocytes; Lipids; Lymphatic System; Lymphocyte Activation; Lymphocytes; Lysine; Oxidative Phosphorylation; Pentoses; Protein Biosynthesis; Thoracic Duct; Thymidine; Uridine | 1970 |
RNA and histone metabolism in small lymphocytes stimulated by phytohaemagglutinin.
Topics: Acetates; Carbon Isotopes; Centrifugation, Density Gradient; Culture Techniques; DNA; Histones; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Methionine; Methylation; RNA; Stimulation, Chemical; Thymidine; Tritium; Uridine | 1970 |
The reaction of 2'(3')-O-bromoacetyluridine with ribonuclease A.
Topics: Acetates; Alkylation; Amino Acids; Animals; Binding Sites; Cattle; Histidine; Iodoacetates; Kinetics; Nucleosides; Pancreas; Ribonucleases; Spectrophotometry; Ultraviolet Rays; Uridine | 1970 |
Transient stimulation of deoxyribonucleic acid-dependent ribonucleic acid polymerase and histone acetylation in human embryonic kidney cultures infected with adenovirus 2 or 12: apparent induction of host ribonucleic acid synthesis.
Topics: Acetates; Adenoviridae; Carbon Isotopes; Culture Techniques; DNA; Enzyme Activation; Genetics, Microbial; Histones; Humans; Hybridization, Genetic; Ions; Kidney; Magnesium; Manganese; Puromycin; RNA; RNA Nucleotidyltransferases; Tritium; Uridine | 1970 |
Effect of nucleotides on the transport of alkali metal cations catalyzed by ionophorous antibiotics across mitochondrial membranes.
Topics: Acetates; Adenine Nucleotides; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Biological Transport; Glutamates; In Vitro Techniques; Lithium; Male; Membranes; Mitochondria; Nucleosides; Nucleotides; Organophosphonates; Oxidative Phosphorylation; Phosphates; Potassium; Rats; Succinates; Thymidine; Uridine | 1970 |
A DNA-like RNA fraction in the posterior silkgland of the wax moth, Galleria mellonella (L.).
Topics: Acetates; Animals; Bombyx; Centrifugation, Density Gradient; Detergents; DNA; Drug Stability; Electrophoresis; Fibroins; Larva; Methylation; Nucleic Acid Hybridization; Nucleotides; Phosphates; Phosphorus Isotopes; Ribosomes; RNA; RNA, Messenger; RNA, Ribosomal; Sulfuric Acids; Time Factors; Tritium; Uridine | 1971 |
Histone acetylation in insect chromosomes.
Topics: Acetates; Animals; Arginine; Autoradiography; Cattle; Cell Nucleus; Chromosomes; Diptera; Histones; Hydrochloric Acid; Liver; Rats; RNA; Salivary Glands; Thymus Gland; Tritium; Uridine | 1968 |
[Alkylation of nucleic acids. II. Study of alkylation of ribonucleic acids].
Topics: Acetates; Alkenes; Alkylation; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Gel; Dimethylformamide; Nucleosides; Potassium; Ribosomes; RNA; RNA, Transfer; Saccharomyces; Solvents; Spectrum Analysis; Temperature; Ultraviolet Rays; Uridine | 1968 |
Acetylation of nucleosides and acetyl migration.
Topics: Acetates; Chemical Phenomena; Chemistry; Nucleosides; Uridine | 1968 |
The effect of N-acetyl-D-galactosamine and amantadine hydrochloride on equine lymphocytes stimulated with phytohemagglutinin.
Topics: Acetates; Alanine; Amantadine; Animals; Carbon Isotopes; Cell Membrane Permeability; Culture Techniques; Galactose; Hexosamines; Horses; Lectins; Lipid Metabolism; Lymphocytes; Proteins; RNA; Time Factors; Uridine | 1969 |
Biochemical effects of the Vinca alkaloids. IV. Studies with vinleurosine.
Topics: Acetates; Alkaloids; Animals; Antineoplastic Agents; Carbon Isotopes; Cell Division; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Glutamates; Indoles; Lipids; Mice; Neoplasm Proteins; Nucleosides; RNA, Neoplasm; Sarcoma 180; Tritium; Uridine | 1969 |
A new method for the assay of glycolytic activity with special reference to microorganisms.
Topics: Acetates; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Fermentation; Formates; Glucose; Glycerol; Glycolysis; Lactates; Methods; Streptococcus; Time Factors; Uridine | 1969 |
[Cytostatically active N-acyloxymethyl compounds].
Topics: Acetates; Animals; Antineoplastic Agents; Benzoates; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cinnamates; Depression, Chemical; DNA, Neoplasm; Esters; Imidazoles; Imides; In Vitro Techniques; Leucine; Mice; Morpholines; Neoplasm Proteins; Oxazoles; Piperidines; Pyrrolidinones; RNA, Neoplasm; Thymidine; Uridine | 1969 |
Binding of labeled ribonucleic acid to basic proteins, a major diffic- ulty in ribonucleic acid-deoxyribonucleic acid hybridization in fixed cells in situ.
Topics: Acetates; Animals; Annelida; Ethanol; Germ Cells; Hybridization, Genetic; In Vitro Techniques; Insecta; Liver; Magnesium Sulfate; Male; Mice; Plant Proteins; Polyvinyls; Protein Binding; Proteins; Ribonucleases; Sodium Chloride; Sulfates; Testis; Trichloroacetic Acid; Tritium; Uridine; Vegetables | 1969 |
Nucleoprotein changes and initiation of RNA synthesis in PHA stimulated lymphocytes.
Topics: Acetates; Acridines; Autoradiography; Binding Sites; Carbon Isotopes; Culture Media; Culture Techniques; Dactinomycin; DNA; Histones; Humans; Lectins; Lymphocytes; RNA; Time Factors; Tritium; Uridine | 1969 |
New acetylating agents for nucleosides: acetylated cyclohydroxamic acids.
Topics: Acetates; Hydroxamic Acids; Nucleosides; Uridine | 1965 |
Anomalous electrophoretic behavior of purine and pyrimidine derivatives in triethylammonium buffers.
Topics: Acetates; Adenine; Bicarbonates; Buffers; Carbonates; Cytosine; Formates; Guanine; Purines; Pyrimidines; Quaternary Ammonium Compounds; Thymine; Uracil; Uracil Nucleotides; Uridine; Xanthines | 1966 |
Evidence for multiple forms of isocitrate lyase in Neurospora crassa.
Topics: Acetates; Chromatography; Enzyme Repression; Glucose; Hot Temperature; Lyases; Molecular Biology; Mutation; Neurospora; Pyruvates; Uridine | 1967 |
Gene activation without histone acetylation in Drosophila melanogaster.
Topics: Acetates; Animals; Autoradiography; Chromosomes; Drosophila; Genes; Histones; RNA; Salivary Glands; Tritium; Uridine | 1967 |
Extracellular calcium ion concentration required for prolactin to express its actions on casein, ribonucleic acid, and lipid biosynthesis in mouse mammary gland explants.
Topics: Acetates; Animals; Calcium; Caseins; Egtazic Acid; Female; Leucine; Lipids; Mammary Glands, Animal; Mice; Pregnancy; Prolactin; RNA; Uridine | 1983 |
Early action of prolactin on ornithine decarboxylase activity is not essential for the subsequent actions of prolactin on casein and lipid biosynthesis.
Topics: Acetates; Animals; Caseins; Cells, Cultured; Female; Leucine; Lipids; Mammary Glands, Animal; Ornithine Decarboxylase; Pregnancy; Prolactin; RNA; Uridine | 1983 |
The effects of aspirin and acetaminophen on tetrahymena pyriformis GL growth and macromolecular synthesis.
Topics: Acetaminophen; Acetates; Acetic Acid; Animals; Aspirin; DNA; Lipids; RNA; Tetrahymena pyriformis; Thymidine; Time Factors; Uridine | 1984 |
The effects of 17 beta estradiol and tamoxifen on the ZR-75-1 human breast cancer cell line in defined medium.
Topics: Acetates; Breast Neoplasms; Cell Division; Cell Line; Culture Media; Estradiol; Female; Humans; Leucine; Tamoxifen; Thymidine; Thymidine Kinase; Time Factors; Uridine | 1980 |
Ribose biosynthesis and evidence for an alternative first step in the common aromatic amino acid pathway in Methanococcus maripaludis.
Topics: Acetates; Amino Acids; Culture Media; Cytidine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanococcus; Pentose Phosphate Pathway; Ribose; Sugar Phosphates; Uridine | 1997 |
Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2',3',5'-tri-O-acetyluridine, a prodrug of uridine.
Topics: Acetates; Animals; Antimetabolites, Antineoplastic; Barbiturates; Drug Interactions; Enzyme Inhibitors; Female; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Prodrugs; Tumor Cells, Cultured; Uridine; Uridine Phosphorylase | 2000 |
Effect of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on plasma concentration of uridine released from 2',3',5'-tri-O-acetyluridine, a prodrug of uridine: relevance to uridine rescue in chemotherapy.
Topics: Acetates; Animals; Biological Availability; Drug Synergism; Enzyme Inhibitors; Female; Mice; Organoselenium Compounds; Prodrugs; Uracil; Uridine; Uridine Phosphorylase | 2000 |
In vitro and in vivo activities of three acridine thioethers against Leishmania donovani.
Topics: Acetates; Acridines; Animals; Antiprotozoal Agents; Cell Division; Cell Line; Dose-Response Relationship, Drug; Ethanol; Lactic Acid; Leishmania donovani; Leishmaniasis, Visceral; Leucine; Macrophages; Mice; Microscopy, Electron; Pyruvates; Rats; Rats, Wistar; Spleen; Structure-Activity Relationship; Succinic Acid; Thymidine; Time Factors; Tritium; Uridine | 2002 |
THE CHEMICAL SYNTHESIS OF THE 1-PHOSPHATE AND THE URIDINE DIPHOSPHATE DERVATIVE OF N-ACETYLCHONDROSINE (O-(BETA-D-GLUCOPYRANOSYLURONIC ACID) (1---3)-2-ACETAMIDO-2-DEOXY-D-GALACTOSE).
Topics: Acetates; Acetylgalactosamine; Alkylation; Chemical Phenomena; Chemistry; Chromatography; Disaccharides; Galactose; Nucleosides; Phosphates; Pyridines; Research; Uracil Nucleotides; Uridine; Uridine Diphosphate; Uronic Acids | 1965 |
Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease.
Topics: Acetates; Administration, Oral; Animals; Huntington Disease; Male; Mice; Mitochondria; Motor Activity; Nerve Degeneration; Nitro Compounds; Prodrugs; Propionates; Uridine; Weight Loss | 2003 |
Neuroprotective effects of oral administration of triacetyluridine against MPTP neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acetates; Animals; Dietary Supplements; Disease Models, Animal; Dopamine; Homovanillic Acid; Mice; MPTP Poisoning; Neuroprotective Agents; Neurotoxins; Uridine | 2004 |
5-Fluorouracil dose escalation enabled with PN401 (triacetyluridine): toxicity reduction and increased antitumor activity in mice.
Topics: Acetates; Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Survival Rate; Tumor Burden; Uridine; Xenograft Model Antitumor Assays | 2006 |
Severe cytochrome c oxidase inhibition in vivo does not induce a pyrimidine deficiency; neuroprotective action of oral uridine prodrug PN401 requires supraphysiological levels of uridine.
Topics: Acetates; Animals; Apoptosis; Aspartic Acid; Azides; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex IV; Enzyme Inhibitors; Fibroblasts; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Phosphonoacetic Acid; Prodrugs; Pyrimidines; Uridine | 2005 |
Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases.
Topics: Acetates; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Humans; Immunologic Factors; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Remission Induction; Uridine; Vitamin B Complex | 2006 |
Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease.
Topics: Acetates; Administration, Oral; Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Female; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity; Neostriatum; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Prodrugs; Rotarod Performance Test; Uridine | 2006 |
A rational approach to the regioselective deacetylation of 2',3',5'-tri-O-acetyluridine by Novozym 435 catalysed alcoholysis.
Topics: Acetates; Acetylation; Amino Acid Motifs; Biocatalysis; Candida; Catalytic Domain; Computer Simulation; Enzymes, Immobilized; Ethanol; Fungal Proteins; Hydrogen Bonding; Hydrolysis; Kinetics; Lipase; Models, Molecular; Protein Binding; Uridine; Water | 2012 |
Uridine prodrug improves memory in Tg2576 and TAPP mice and reduces pathological factors associated with Alzheimer's disease in related models.
Topics: Acetates; Alzheimer Disease; Animals; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Female; Gerbillinae; Humans; Male; Maze Learning; Memory; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Prodrugs; Stroke; Uridine | 2013 |
FDA approves therapy to treat overdose of fluorouracil, capecitabine.
Topics: Acetates; Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Chemistry, Pharmaceutical; Drug Approval; Drug Overdose; Fluorouracil; Humans; United States; United States Food and Drug Administration; Uridine | 2016 |
In brief: Uridine triacetate (Xuriden) for hereditary orotic aciduria.
Topics: Acetates; Administration, Oral; Biomarkers; Drug Costs; Humans; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine-Pyrimidine Metabolism, Inborn Errors; Treatment Outcome; Uridine | 2016 |
Benefit of uridine triacetate (Vistogard) in rescuing severe 5-fluorouracil toxicity in patients with dihydropyrimidine dehydrogenase (DPYD) deficiency.
Topics: Acetates; Aged; Antidotes; Antimetabolites, Antineoplastic; Dihydropyrimidine Dehydrogenase Deficiency; Female; Fluorouracil; Humans; Male; Pancreatic Neoplasms; Severity of Illness Index; Time Factors; Uridine | 2016 |
In brief: uridine triacetate (Vistogard) for fluorouracil overdose.
Topics: Acetates; Antidotes; Antimetabolites, Antineoplastic; Drug Overdose; Fluorouracil; Humans; Treatment Outcome; Uridine | 2016 |
Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity.
Topics: Acetates; Antimetabolites, Antineoplastic; Capecitabine; Drug Overdose; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Uridine | 2017 |
An antidote to fluorouracil and capecitabine toxicity.
Topics: Acetates; Antidotes; Antineoplastic Agents; Capecitabine; Drug Costs; Drug Overdose; Fluorouracil; Humans; Treatment Outcome; Uridine | 2016 |
Early-Onset 5-Fluorouracil Toxicity in a Patient Negative for Dihydropyrimidine Dehydrogenase Mutations: The Clinical Course of Reversal with Uridine Triacetate.
Topics: Acetates; Aged; Antidotes; Antimetabolites, Antineoplastic; Anus Neoplasms; Dihydrouracil Dehydrogenase (NADP); Fatigue; Fluorouracil; Follow-Up Studies; Humans; Male; Mucositis; Mutation; Neutrophils; Time Factors; Uridine | 2016 |
The successful treatment of 5-fluorouracil (5-FU) overdose in a patient with malignancy and HIV/AIDS with uridine triacetate.
Topics: Acetates; Antimetabolites, Antineoplastic; Anus Neoplasms; Depression; Drug Overdose; Emergency Medicine; Fluorouracil; HIV Infections; Humans; Male; Middle Aged; Toxoplasmosis, Cerebral; Treatment Outcome; Uridine | 2017 |
Age-related changes in skeletal muscle composition: A pilot nuclear magnetic resonance spectroscopy study in mice.
Topics: Acetates; Aging; Animals; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Pilot Projects; Principal Component Analysis; Quadriceps Muscle; Taurine; Uridine | 2017 |
Assessment of the imprinting efficiency of an imide with a "stoichiometric" pyridine-based functional monomer in precipitation polymerisation.
Topics: Acetates; Hydrogen Bonding; Imides; Macromolecular Substances; Molecular Imprinting; Polymerization; Polymers; Pyridines; Uridine | 2018 |
Case report of capecitabine toxicity and use of uridine triacetate.
Topics: Acetates; Aged; Antimetabolites, Antineoplastic; Capecitabine; Diarrhea; Drug Eruptions; Fatal Outcome; Humans; Liver Neoplasms; Male; Mucositis; Uridine | 2019 |
Prompt treatment with uridine triacetate improves survival and reduces toxicity due to fluorouracil and capecitabine overdose or dihydropyrimidine dehydrogenase deficiency.
Topics: Acetates; Animals; Antidotes; Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Dose-Response Relationship, Drug; Drug Overdose; Female; Fluorouracil; Mice; Survival Analysis; Uridine | 2018 |
Anomalous interaction of tri-acyl ester derivatives of uridine nucleoside with a l-α-dimyristoylphosphatidylcholine biomembrane model: a differential scanning calorimetry study.
Topics: Acetates; Calorimetry, Differential Scanning; Dimyristoylphosphatidylcholine; Esters; Fatty Acids; Membranes; Models, Theoretical; Nucleosides; Phospholipids; Uridine | 2019 |
[5-FU: At last!]
Topics: Acetates; Antidotes; Antimetabolites, Antineoplastic; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Humans; Neoplasms; Practice Guidelines as Topic; Pyrimidines; Uracil; Uridine | 2019 |
Real-time comprehensive toxicology testing in the clinical management of accidental pediatric capecitabine ingestion.
Topics: Acetates; Antidotes; Antimetabolites, Antineoplastic; Capecitabine; Child, Preschool; Humans; Male; Uridine | 2020 |
Use of Uridine Triacetate to Reverse Severe Persistent Myelosuppression Following 5-fluorouracil Exposure in a Patient With a c.557A>G Heterozygous DPYD Variant.
Topics: Acetates; Fluorouracil; Humans; Neoplasms; Uridine | 2021 |