Page last updated: 2024-08-17

uridine and gemcitabine

uridine has been researched along with gemcitabine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's6 (46.15)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T1
Hong, J; Johnson, ZL; Kwon, DY; Lee, JH; Lee, K; Lee, M; Lee, SY1
Wiley, JS1
Burke, T; Ferguson, PJ; Hammond, JR; Lee, S1
Ferguson, PJ; Hammond, JR; Lee, S1
Baldwin, SA; Cass, CE; Karpinski, E; Mackey, JR; Smith, KM; Yao, SY; Young, JD1
Casado, FJ; Inzillo, SM; Larrayoz, IM; Lostao, MP; Mata, JF; Pastor-Anglada, M1
Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD1
Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K1
Bouffard, DY; Cass, CE; Clarke, ML; Damaraju, VL; Gourdeau, H; Grey, M; Leblond, L; Mackey, JR; Wong, CK1
Carbó, N; Casado, FJ; García-Manteiga, J; Mazo, A; Mercadé, E; Pastor-Anglada, M; Pérez-Torras, S1
Cass, CE; Damaraju, VL; Kuzma, M; Mowles, D; Ryan, AJ; Sawyer, MB; Scriver, T1
Bugde, P; Hawkins, BC; Li, Y; Paxton, JW; Revalde, JL; Rosengren, RJ; Wijeratne, TS1

Other Studies

13 other study(ies) available for uridine and gemcitabine

ArticleYear
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication

2007
Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
    eLife, 2014, Jul-31, Volume: 3

    Topics: Animals; Bacterial Proteins; Binding Sites; Biological Transport; Crystallography, X-Ray; Deoxycytidine; Female; Gemcitabine; Gene Expression; Humans; Kinetics; Membrane Transport Proteins; Molecular Docking Simulation; Nucleoside Transport Proteins; Oocytes; Protein Binding; Quantitative Structure-Activity Relationship; Recombinant Proteins; Ribavirin; Substrate Specificity; Thermodynamics; Uridine; Vibrio cholerae; Xenopus laevis

2014
Seeking the nucleoside transporter.
    Nature medicine, 1997, Volume: 3, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Membrane; Cladribine; Cloning, Molecular; Cytarabine; Deoxycytidine; Erythrocytes; Gemcitabine; Glucose Transporter Type 1; Humans; Leukemia; Lymphoma; Membrane Proteins; Monosaccharide Transport Proteins; Nucleosides; Oocytes; Recombinant Proteins; Uridine; Vidarabine; Xenopus

1997
Interaction of 2',2'-difluorodeoxycytidine (gemcitabine) and formycin B with the Na+-dependent and -independent nucleoside transporters of Ehrlich ascites tumor cells.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Carrier Proteins; Deoxycytidine; Formycins; Gemcitabine; Male; Membrane Proteins; Mice; Nucleoside Transport Proteins; Sodium; Thioinosine; Uridine

1998
[3H]gemcitabine uptake by nucleoside transporters in a human head and neck squamous carcinoma cell line.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Carrier Proteins; Deoxycytidine; Drug Resistance; Formycins; Gemcitabine; Head and Neck Neoplasms; Humans; Membrane Proteins; Nucleoside Transport Proteins; Time Factors; Tritium; Tumor Cells, Cultured; Uridine

1999
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters.
    Journal of the National Cancer Institute, 1999, Nov-03, Volume: 91, Issue:21

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Cell Membrane; Deoxycytidine; Electrophysiology; Gemcitabine; Membrane Proteins; Neoplasms; Nucleosides; Oocytes; Recombinant Proteins; Sodium Channels; Uridine; Xenopus laevis

1999
Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes.
    FEBS letters, 2000, Sep-15, Volume: 481, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Carrier Proteins; Cytidine; Deoxycytidine; Electric Conductivity; Gemcitabine; Gene Expression; Humans; Membrane Potentials; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Oocytes; Sodium; Substrate Specificity; Uridine; Vidarabine; Xenopus laevis

2000
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Male; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Prostatic Neoplasms; Sequence Homology, Amino Acid; Sodium; Stereoisomerism; Tritium; Tumor Cells, Cultured; Uridine

2001
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
    Biochemical and biophysical research communications, 2006, Aug-25, Volume: 347, Issue:2

    Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine

2006
Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer.
    BMC cancer, 2007, Jul-03, Volume: 7

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytosine; Deoxycytidine; Dioxolanes; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Nude; Mice, SCID; Pancreatic Neoplasms; Treatment Outcome; Tritium; Tumor Cells, Cultured; Uridine; Xenograft Model Antitumor Assays

2007
Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer.
    Biochemical pharmacology, 2008, Aug-01, Volume: 76, Issue:3

    Topics: Adenocarcinoma; Adenoviridae; Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Survival; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Female; Gemcitabine; Genetic Vectors; Humans; Injections, Intralesional; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Protein Biosynthesis; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Uridine; Xenograft Model Antitumor Assays

2008
Erlotinib, gefitinib, and vandetanib inhibit human nucleoside transporters and protect cancer cells from gemcitabine cytotoxicity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jan-01, Volume: 20, Issue:1

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Screening Assays, Antitumor; Drug Synergism; Erlotinib Hydrochloride; Gefitinib; Gemcitabine; Humans; Inhibitory Concentration 50; Nucleoside Transport Proteins; Piperidines; Quinazolines; Saccharomyces cerevisiae; Uridine

2014
Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells.
    European journal of pharmacology, 2017, May-15, Volume: 803

    Topics: Antineoplastic Agents; Cell Line, Tumor; Curcumin; Cyclohexanones; Deoxycytidine; Drug Interactions; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Pancreatic Neoplasms; Uridine

2017