uridine has been researched along with deoxycytidine in 102 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (67.65) | 18.7374 |
| 1990's | 10 (9.80) | 18.2507 |
| 2000's | 15 (14.71) | 29.6817 |
| 2010's | 4 (3.92) | 24.3611 |
| 2020's | 4 (3.92) | 2.80 |
| Authors | Studies |
|---|---|
| Chawla, RR; Hampton, A; Kappler, F | 2 |
| Bloomer, LC; Patil, VD; Townsend, LB; Wise, DS; Wotring, LL | 1 |
| Baker, BJ; McClintock, JB; Moon, B | 1 |
| Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T | 1 |
| Harano, A; Hatano, A; Nakagomi, Y; Naramoto, Y; Takigawa, Y; Toda, K; Yamada, H | 1 |
| Clements, GB | 1 |
| Abbasi, MM; Beisler, JA; Voytek, P; Wolpert-DeFilippes, MK | 1 |
| Chan, TS | 1 |
| de Bree, PK; Grift, J; Stoop, JW; van Gennip, AH; Wadman, SK; Zegers, BJ | 1 |
| Shall, S | 1 |
| Brockman, RW; Nelson, JA; Rose, LM; Schabel, FM; Shaddix, SC; Williams, M | 1 |
| Eckstein, F; Hobbs, J | 1 |
| Hoshi, A; Riesz, P; Rustgi, S | 1 |
| van Rooijen, N | 1 |
| Roy-Burman, S; Visser, DW; von Dippe, PJ | 1 |
| Rima, BK; Takahashi, I | 2 |
| Edelman, IS; Inciardi, JF; Rossier, BC; Wilce, PA; Yoshimura, FK | 1 |
| Ariga, H; Shimojo, H | 1 |
| Momparler, LF; Momparler, RL; Rivard, GE; Veselý, J | 1 |
| Fujimura, S; Shimizu, M | 1 |
| Mygind, B | 1 |
| Baguley, BC; Falkenhaug, EM | 1 |
| Furner, RL; Herren, TC; Mellett, LB | 1 |
| Leung, K; Roy-Burman, S; Visser, DW; von Dippe, PJ | 1 |
| Kato, S; Mantani, M | 1 |
| Brun, G; Goodgame, DM; Skapski, AC | 1 |
| Clements, GB; Subak-Sharpe, JH | 1 |
| Fischer, GA; Theiss, JC | 1 |
| Mejer, J | 1 |
| August, EM; Marongiu, ME; Prusoff, WH | 1 |
| Boothman, DA; Briggle, TV; Greer, S | 3 |
| Davis, MA; Lawrence, TS | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Schols, D; Van Aerschot, A | 1 |
| Chu, EH; Li, IC; Wu, CL | 1 |
| Boothman, DA; Greer, SB; Mekras, JA | 1 |
| Binnie, C; Coote, JG | 1 |
| Greer, S; Perez, LM | 1 |
| Ayers, O; Malinowski, N; Moyer, JD | 1 |
| Bertinchamps, AJ; Mathur-De Vré, R | 1 |
| Blandin, M; Catlin, JC; Guschlbauer, W | 1 |
| Komatsu, Y; Tanaka, K | 1 |
| Durham, JP; Galanti, N | 1 |
| Cory, JG; George, CB; Mansell, MM; Wilkinson, DS | 1 |
| Swetly, P; Watanabe, Y | 1 |
| Sato, K; Shiomi, T | 1 |
| Bloch, A; McPartland, RP; Wang, MC; Weinfeld, H | 1 |
| Ho, DH | 1 |
| Durham, JP; Hay, J; Howard, DK; Melvin, WT | 1 |
| Hofert, JF | 1 |
| Taketo, A; Taketo, Y | 1 |
| Berger, AE; Kuentzel, SL; Neil, GL | 1 |
| Loeb, LA; Williams, RO | 1 |
| Cooper, GM; Greer, S | 1 |
| Jekunen, A; Puukka, M; Vilpo, J | 1 |
| Briggle, TV; Greer, S; Mekras, JA; Perez, LM | 1 |
| Hudson, JB | 1 |
| Mathews, CK; North, TW | 1 |
| Böhmer, FD; Graetz, H; Grosse, R; Langen, P; Lehmann, W | 1 |
| Evans, DI; Layward, L; Simmonds, HA; Watson, AR; Webster, DR | 1 |
| Duran, M; Kuis, W; Rijkers, GT; Rijksen, G; Roord, JJ; Spaapen, LJ; Staal, GE; Stoop, JW; Wadman, SK; Zegers, BJ | 1 |
| Boothman, DA; Greer, S; Mekras, JA; Perez, LM | 1 |
| Evans, WE; Sinkule, JA | 1 |
| Jekunen, A; Vilpo, JA | 1 |
| Bismuth, G; Cartier, PH; Perignon, JL; Thuillier, L | 1 |
| Jarvis, SM; McBride, D; Young, JD | 1 |
| Braun, TJ; Burchenal, JH; Chou, TC; Fox, JJ; Philips, FS; Schmid, FA; Su, TL; Watanabe, KA | 1 |
| Katz, DJ; Townsend, LB; Wise, DS | 1 |
| Deveski, WB; Dudman, NP; Tattersall, MH | 1 |
| Sasvari-Szekely, M; Solymossy, M; Staub, M; Szikla, K | 1 |
| Andersen, PS; Hammer, K; Martinussen, J | 1 |
| Wiley, JS | 1 |
| Burke, T; Ferguson, PJ; Hammond, JR; Lee, S | 1 |
| Ferguson, PJ; Hammond, JR; Lee, S | 1 |
| Erbs, P; Exinger, F; Jund, R; Kurtz, JE | 1 |
| Baldwin, SA; Cass, CE; Karpinski, E; Mackey, JR; Smith, KM; Yao, SY; Young, JD | 1 |
| Casado, FJ; Inzillo, SM; Larrayoz, IM; Lostao, MP; Mata, JF; Pastor-Anglada, M | 1 |
| Kodama, T; Matsuda, A; Nomura, M; Shuto, S | 1 |
| Evans, VJ; Price, FM; Rotherham, J | 2 |
| Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD | 1 |
| Kobori, A; Miyata, K; Seio, K; Sekine, M; Ushioda, M | 1 |
| Ashihara, H; Katahira, R | 1 |
| Li, NS; Piccirilli, JA | 2 |
| Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K | 1 |
| Bouffard, DY; Cass, CE; Clarke, ML; Damaraju, VL; Gourdeau, H; Grey, M; Leblond, L; Mackey, JR; Wong, CK | 1 |
| Beumer, JH; Doroshow, JH; Egorin, MJ; Lenz, HJ; Newman, EM; Parise, RA; Synold, TW | 1 |
| Carbó, N; Casado, FJ; García-Manteiga, J; Mazo, A; Mercadé, E; Pastor-Anglada, M; Pérez-Torras, S | 1 |
| Iams, TA; McKee, EE; Morris, GW; Slepchenko, KG | 1 |
| Saada, A | 1 |
| Cass, CE; Damaraju, VL; Kuzma, M; Mowles, D; Ryan, AJ; Sawyer, MB; Scriver, T | 1 |
| Hong, J; Johnson, ZL; Kwon, DY; Lee, JH; Lee, K; Lee, M; Lee, SY | 1 |
| Berridge, G; Goldin, R; Kessler, BM; Kriaucionis, S; Pugh, KM; Thézénas, ML; Zauri, M | 1 |
| Bugde, P; Hawkins, BC; Li, Y; Paxton, JW; Revalde, JL; Rosengren, RJ; Wijeratne, TS | 1 |
| Dellafiore, M; Iribarren, AM; Montserrat, JM | 1 |
| Chakrapani, A; Hocek, M; Krásný, L; Pohl, R; Ruiz-Larrabeiti, O; Vaňková Hausnerová, V | 1 |
| Gasparavičiūtė, R; Jauniškis, V; Lapinskaitė, R; Meškienė, R; Meškys, R; Skrodenytė, E; Sūdžius, J; Tamulaitienė, G; Tauraitė, D; Tiškus, M; Urbelienė, N; Urbelis, G; Vaitekūnas, J | 1 |
| Gao, H; Pang, GZ; Rong, SQ; Wang, YX; Zhao, YH; Zhou, D | 1 |
2 review(s) available for uridine and deoxycytidine
| Article | Year |
|---|---|
Selection of biochemically variant, in some cases mutant, mammalian cells in culture.
Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Base Sequence; Carbohydrates; Cell Fusion; Cell Separation; Cells, Cultured; Cricetinae; Dactinomycin; Deoxycytidine; Drug Resistance; Epitopes; Folic Acid; Genes; Genes, Regulator; Guinea Pigs; Hot Temperature; Humans; Immunoglobulins; Mice; Mutation; Nucleosides; Phenotype; Purines; Puromycin; Rabbits; Rats; Temperature; Thymidine; Time Factors; Uracil; Uridine | 1975 |
Labelling of lymphocytes with various radiosotopes for in vivo tracer studies; a review.
Topics: Amino Acids; Carbon Radioisotopes; Chromium Radioisotopes; Deoxycytidine; DNA; Idoxuridine; Isotope Labeling; Lymphocytes; Protein Biosynthesis; Radioisotopes; RNA; Technetium; Thymidine; Tritium; Uridine | 1977 |
2 trial(s) available for uridine and deoxycytidine
| Article | Year |
|---|---|
The effect of deoxycytidine and tetrahydrouridine in purine nucleoside phosphorylase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Clinical Trials as Topic; Deoxycytidine; Erythrocytes; Humans; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Ribonucleotides; Tetrahydrouridine; Uracil; Uridine | 1984 |
Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Deoxycytidine; DNA Modification Methylases; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Reproducibility of Results; Tandem Mass Spectrometry; Tetrahydrouridine; Uridine | 2008 |
98 other study(ies) available for uridine and deoxycytidine
| Article | Year |
|---|---|
Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site.
Topics: Animals; Binding Sites; Cricetinae; Cytoplasm; Escherichia coli; Kinetics; Species Specificity; Structure-Activity Relationship; Thymidine; Thymidine Kinase | 1979 |
Synthesis and biological activity of a novel adenosine analogue, 3-beta-D-ribofuranosylthieno[2,3-d]pyrimidin-4-one.
Topics: Adenosine; Adenosine Kinase; Animals; Antineoplastic Agents; Biotransformation; In Vitro Techniques; Leukemia L1210; Mice; Pyrimidine Nucleosides | 1985 |
Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes.
Topics: Animals; Cytoplasm; In Vitro Techniques; Isoenzymes; Kinetics; Mitochondria; Pyrimidine Nucleosides; Rats; Thymidine; Thymidine Kinase; Tissue Distribution | 1982 |
Purine and nucleoside metabolites from the Antarctic sponge Isodictya erinacea.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Behavior, Animal; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Nucleosides; Porifera; Purines; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Starfish; Tumor Cells, Cultured | 1998 |
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2007 |
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
Topics: Kinetics; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase | 2008 |
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.
Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Synergism; Kinetics; Leukemia L1210; Oxidative Phosphorylation; Tetrahydrouridine; Thymidine; Uridine | 1977 |
Deoxyguanosine toxicity on lymphoid cells as a cause for immunosuppression in purine nucleoside phosphorylase deficiency.
Topics: Cell Division; Cell Line; Cytidine Diphosphate; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanosine; Hypoxanthines; Immunosuppression Therapy; Oxidation-Reduction; Pentosyltransferases; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Ribonucleotides; T-Lymphocytes; Uridine | 1978 |
Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleoside phosphorylase deficiency.
Topics: Allopurinol; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deoxycytidine; Humans; Infant; Ornithine Carbamoyltransferase Deficiency Disease; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; Respiratory Tract Infections; Uracil; Uridine | 1979 |
Proceedings: Experimental manipulation of the specific activity of poly(ADP-ribose) polymerase.
Topics: Animals; Cell Division; Cell Line; Cell Nucleus; Cytidine; Deoxycytidine; Fibroblasts; Kinetics; Male; Mice; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Spermatogenesis; Testis; Time Factors; Trout; Uridine | 1975 |
The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine.
Topics: 3-Deazauridine; Adenocarcinoma; Animals; Cell Line; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Drug Resistance; Leukemia L1210; Liver; Mice; Neoplasms, Experimental; Orotic Acid; Phosphotransferases; Pyrimidine Nucleotides; Ribonucleotide Reductases; Ribonucleotides; RNA, Neoplasm; Uracil Nucleotides; Uridine | 1975 |
Hydrolysis in 2'-chloro-2'-deoxy nucleosides, -nucleotides and -polynucleotides to arabinose-derivatives.
Topics: Alkaline Phosphatase; Arabinose; Chemical Phenomena; Chemistry; Chlorine; Deoxycytidine; Deoxyribonucleosides; Deoxyribonucleotides; Hydrolysis; Kinetics; Phosphoric Diester Hydrolases; Polynucleotides; Tromethamine; Uridine | 1975 |
E.s.r. of spin-trapped radicals in gamma-irradiated aqueous solutions of nucleic acids and their constituents.
Topics: Cobalt Radioisotopes; Cytidine Monophosphate; Cytosine; Deoxycytidine; DNA; Electron Spin Resonance Spectroscopy; Gamma Rays; Poly U; Thymidine; Thymidine Monophosphate; Thymine; Uracil; Uridine | 1976 |
Mechanism of energy coupling for transport of deoxycytidine, uridine, uracil, adenine and hypoxanthine in Escherichia coli.
Topics: Adenine; Biological Transport, Active; Deoxycytidine; Electron Transport; Energy Metabolism; Escherichia coli; Hypoxanthines; Oxidative Phosphorylation; Uracil; Uridine | 1978 |
Metabolism of pyrimidine bases and nucleosides in Bacillus subtilis.
Topics: Bacillus subtilis; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxyuridine; DNA, Bacterial; Mutation; Nucleoside Deaminases; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Uracil; Uridine | 1977 |
Effects of 3'-deoxycytidine on rRNA synthesis in toad bladder: analysis of response to aldosterone.
Topics: Aldosterone; Animals; Biological Transport; Bufo marinus; Cell Nucleus; Cytoplasm; Deoxycytidine; Drug Interactions; Female; In Vitro Techniques; Poly A; RNA, Messenger; RNA, Ribosomal; Sodium; Uridine; Urinary Bladder | 1977 |
Incorporation of uracil into the growing strand of adenovirus 12 DNA.
Topics: Adenoviruses, Human; Deoxycytidine; DNA Repair; DNA Replication; DNA, Viral; Hydroxyurea; Molecular Weight; Uracil; Uridine; Virus Replication | 1979 |
Synergistic action of 5-aza-2'-deoxycytidine and 3-deazauridine on L1210 leukemic cells and EMT6 tumor cells.
Topics: 3-Deazauridine; Animals; Cell Division; Cell Survival; Cells, Cultured; Deoxycytidine; DNA, Neoplasm; Drug Synergism; Leukemia L1210; Male; Mammary Neoplasms, Experimental; Mice; Uridine | 1979 |
Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.
Topics: Animals; Cytidine; Deoxycytidine; Liver; Male; Neoplasm Transplantation; Orotic Acid; Pseudouridine; Pyrimidine Nucleosides; Rats; Sarcoma, Yoshida; Uridine | 1978 |
Transport of pyrimidine nucleosides in cells of Escherichia coli K 12.
Topics: Biological Transport, Active; Culture Media; Cytidine; Deoxycytidine; Dinitrophenols; Escherichia coli; Ethylmaleimide; Genotype; Kinetics; Mercuribenzoates; Methylnitronitrosoguanidine; Mutation; Pyrimidine Nucleosides; Radiation Effects; Species Specificity; Ultraviolet Rays; Uridine | 1975 |
Plasma half-life of cytosine arabinoside in patients with leukaemia--the effect of uridine.
Topics: Administration, Oral; Aminohydrolases; Animals; Cell Count; Cytarabine; Deoxycytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Mice; Uridine | 1975 |
Influence of tetrahydrouridine on the phosphorylation of 1-beta-D-arabinofuranosyl-cytosine (ara-C) by enzymes from solid tumors in vitro.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Cytarabine; Cytidine Deaminase; Deoxycytidine; Female; In Vitro Techniques; Kinetics; L Cells; Liver; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Phosphorus; Phosphotransferases; Sarcoma 180; Spleen; Tetrahydrouridine; Uridine | 1975 |
Deoxycytidine transport in the presence of a cytidine deaminase inhibitor and the transport of uracil in Escherichia coli B.
Topics: Adenine Phosphoribosyltransferase; Anti-Bacterial Agents; Arsenates; Biological Transport; Cyanides; Cytidine; Cytidine Deaminase; Deoxyadenosines; Deoxycytidine; Escherichia coli; Guanosine; Kinetics; Nucleoside Deaminases; Pentosyltransferases; Tetrahydrouridine; Time Factors; Uracil; Uridine | 1975 |
Relationship between virus multiplication and culture cells synchronized by excess thymidine treatment. V. Effect of chikungunya virus infection upon the host cell cycle.
Topics: Amnion; Antigens, Viral; Autoradiography; Cell Line; Chikungunya virus; Clone Cells; Colchicine; Deoxycytidine; DNA, Viral; Fluorescent Antibody Technique; Humans; Mitosis; RNA, Viral; Thymidine; Tritium; Uridine | 1975 |
Reaction of ribonucleosides and deoxynucleosides with copper(II) acetate.
Topics: Acetates; Chemical Phenomena; Chemistry; Copper; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Ribonucleosides; Spectrum Analysis; Thymidine; Uridine | 1975 |
Reactivation of chick erythrocyte nuclei in BHK derived cells with multiple biochemical lesions.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Fusion; Cell Line; Cell Nucleolus; Cell Nucleus; Deoxycytidine; DNA; Erythrocytes; Guanosine; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; RNA; Thymidine; Uridine | 1975 |
Inhibition of intracellular pyrimidine ribonucleotide reduction by deoxycytidine, arabinosylcytosine and hydroxyurea.
Topics: Cell Line; Cytarabine; Deoxycytidine; Hydroxyurea; Oxidation-Reduction; Pyrimidine Nucleotides; Uridine | 1976 |
The impact of selected nucleosides on the cytotoxicity of Ara-C in HL60 cells.
Topics: Cell Line; Cell Survival; Cytarabine; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Interactions; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nucleosides; Tetrahydrouridine; Uridine | 1991 |
Effect of 3'-deoxythymidin-2'-ene (d4T) on nucleoside metabolism in H9 cells.
Topics: Amino Acids; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; Dideoxynucleosides; Humans; Nucleosides; Stavudine; Thymidine; Thymidine Kinase; Uridine | 1990 |
Protective, tumor-selective dual pathway activation of 5-fluoro-2'-deoxycytidine provided by tetrahydrouridine in mice bearing mammary adenocarcinoma-755.
Topics: Animals; Antimetabolites; Chromatography, High Pressure Liquid; Cytidine Deaminase; DCMP Deaminase; Deoxycytidine; DNA; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; RNA; Tetrahydrouridine; Uridine | 1987 |
Metabolic channeling of 5-fluoro-2'-deoxycytidine utilizing inhibitors of its deamination in cell culture.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cytidine Deaminase; Deamination; Deoxycytidine; DNA; Liver Neoplasms, Experimental; Nucleoside Deaminases; RNA; Tetrahydrouridine; Uridine | 1985 |
Selective radiosensitization and cytotoxicity of human melanoma cells using halogenated deoxycytidines and tetrahydrouridine.
Topics: Antineoplastic Agents; Bromodeoxycytidine; Cell Line; Deoxycytidine; Fibroblasts; Humans; In Vitro Techniques; Melanoma; Radiation-Sensitizing Agents; Tetrahydrouridine; Tumor Cells, Cultured; Uridine | 1989 |
5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine.
Topics: Antiviral Agents; Cell Transformation, Viral; Deoxycytidine; Dideoxynucleosides; Halogens; HIV; Phosphorylation; Thymidine; Uridine | 1989 |
Single-step selection of mammalian cell mutants deficient in CTP synthetase.
Topics: Animals; Carbon-Nitrogen Ligases; Cell Line; Cell Separation; Cricetinae; Cytidine; Deoxycytidine; DNA; Ligases; Mutation; Thymidine; Uridine | 1989 |
Use of 5-trifluoromethyldeoxycytidine and tetrahydrouridine to circumvent catabolism and exploit high levels of cytidine deaminase in tumors to achieve DNA- and target-directed therapies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cytidine Deaminase; Deoxycytidine; DNA; Female; Floxuridine; Fluorouracil; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Nucleoside Deaminases; Tetrahydrouridine; Thymidylate Synthase; Trifluridine; Uridine | 1985 |
Tumor-selective metabolism of 5-fluoro-2'-deoxycytidine coadministered with tetrahydrouridine compared to 5-fluorouracil in mice bearing Lewis lung carcinoma.
Topics: Animals; Antimetabolites; Deoxycytidine; Female; Floxuridine; Fluorouracil; Lung Neoplasms; Mice; Tetrahydrouridine; Uridine | 1987 |
Inhibition of sporulation in Bacillus subtilis by bromodeoxyuridine and the effect on DNA replication.
Topics: Bacillus subtilis; Bromodeoxyuridine; Chloramphenicol; Deoxycytidine; DNA Replication; Genetic Markers; Hydroxyphenylazouracil; Spores, Bacterial; Uridine | 1986 |
Sensitization to X ray by 5-chloro-2'-deoxycytidine co-administered with tetrahydrouridine in several mammalian cell lines and studies of 2'-chloro derivatives.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Survival; Deoxycytidine; Drug Combinations; Humans; In Vitro Techniques; Radiation-Sensitizing Agents; Tetrahydrouridine; Uridine | 1986 |
Salvage of circulating pyrimidine nucleosides by tissues of the mouse.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Half-Life; Male; Metabolic Clearance Rate; Mice; Pyrimidine Nucleosides; Thymidine; Tissue Distribution; Uracil; Uridine | 1985 |
The synthesis of nucleic acids in Bacillus subtilis infected with phage PBS 1.
Topics: Bacillus subtilis; Bacteriophages; Dactinomycin; Deoxycytidine; DNA, Bacterial; DNA, Viral; Isotope Labeling; Mutation; Nucleic Acid Hybridization; Rifamycins; RNA, Bacterial; RNA, Viral; Time Factors; Tritium; Uridine | 1973 |
An NMR study of the relative interaction abilities of different pyrimidine nucleosides with serotonin.
Topics: Bromodeoxyuridine; Cytidine; Deoxycytidine; Floxuridine; Idoxuridine; Magnetic Resonance Spectroscopy; Pyrimidine Nucleosides; Serotonin; Thymidine; Uridine | 1974 |
Nucleoside conformations. 16. Nuclear magnetic resonance and circular dichroism studies on pyrimidine-2'-fluoro-2'-deoxyribonucleosides.
Topics: Chromatography, Paper; Chromatography, Thin Layer; Circular Dichroism; Crystallization; Deoxycytidine; Deoxyribonucleosides; Floxuridine; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyrimidine Nucleosides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thiouracil; Uridine | 1974 |
Deoxycytidine uptake by isolated membrane vesicles from Escherichia coli K 12.
Topics: Ascorbic Acid; Azides; Biological Transport; Carbon Isotopes; Cell Fractionation; Cell Membrane; Chloromercuribenzoates; Deoxycytidine; Deoxyribonucleosides; Electron Transport; Escherichia coli; Iodoacetates; Lactates; Mutation; NAD; Nucleosides; Organoids; Proline; Succinates; Thymidine; Time Factors; Uridine | 1973 |
The effect of isoproterenol upon the activity and intracellular distribution of pyrimidine nucleoside kinases in the mouse parotid gland.
Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Cytosol; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; DNA; Female; Isoproterenol; Mice; Microsomes; Mitochondria; Molecular Weight; Parotid Gland; Phosphotransferases; Pyrimidine Nucleosides; Structure-Activity Relationship; Subcellular Fractions; Time Factors; Tritium; Uridine | 1974 |
Inhibition of nucleic acid synthesis in Ehrlich tumor cells by periodate-oxidized adenosine and adenylic acid.
Topics: Adenosine; Adenosine Monophosphate; Animals; Borohydrides; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, Ion Exchange; Chromatography, Paper; Cytidine; Deoxycytidine; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Mice; Oxidation-Reduction; Periodic Acid; Ribonucleotide Reductases; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Time Factors; Tritium; Uridine | 1974 |
Cell cycle dependent transcription of SV40 DNA in SV40-transformed cells.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromatin; Demecolcine; Deoxycytidine; DNA-Directed RNA Polymerases; DNA, Viral; Epithelium; Escherichia coli; Isotope Labeling; Liver; Mitosis; Nucleic Acid Hybridization; Rats; RNA, Viral; Simian virus 40; Thymidine; Time Factors; Transcription, Genetic; Tritium; Uridine | 1974 |
Isolation of temperature-sensitive mutants from murine leukemic cells (L5178Y).
Topics: Agar; Animals; Cell Line; Cell Separation; Cell Survival; Cytarabine; Deoxycytidine; DNA, Neoplasm; Leucine; Leukemia, Lymphoid; Mesylates; Mice; Mutagens; Mutation; Neoplasm Proteins; RNA, Neoplasm; Temperature; Tritium; Uridine | 1974 |
Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.
Topics: Animals; Cells, Cultured; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyuridine; Enzyme Inhibitors; Leukemia L1210; Ligases; Liver; Mice; Thymidine; Uracil Nucleotides; Uridine | 1974 |
Distribution of kinase and deaminase of 1-beta-D-arabinofuranosylcytosine in tissues of man and mouse.
Topics: Aminohydrolases; Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; Humans; Kidney; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Liver; Mice; Phosphotransferases; Spleen; Uridine | 1973 |
Changes in DNA and RNA synthesis and associated enzyme activities after the stimulation of serum-depleted BHK21-C13 cells by the addition of serum.
Topics: Animals; Blood; Carbon Radioisotopes; Carboxy-Lyases; Cell Division; Cell Line; Centrifugation, Density Gradient; Cricetinae; Deoxyadenosines; Deoxycytidine; DNA; DNA Nucleotidyltransferases; DNA Replication; Guanosine; Kidney; Ornithine; Phosphotransferases; RNA; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1974 |
An acute effect of high oxygen tension on the uptake of 3H-deoxycytidine into thymocyte deoxyribonucleic acid.
Topics: Animals; Cells, Cultured; Cytidine; Deoxycytidine; DNA; Oxygen; Rats; T-Lymphocytes; Thymidine; Time Factors; Tritium; Uridine | 1974 |
Nucleoside catabolism in Streptococcus hemolyticus.
Topics: Biodegradation, Environmental; Cell-Free System; Chromatography, Gel; Cytidine; Deoxycytidine; Escherichia coli; Guanosine; Hemolysin Proteins; Nucleosides; Phosphotransferases; Streptococcus; Thymidine; Uridine | 1974 |
A microbiological assay for cyclocytidine--disposition studies in mice.
Topics: Animals; Biological Assay; Cytarabine; Cytidine; Deoxycytidine; Enterococcus faecalis; Female; Mice; Nucleosides; Uridine | 1973 |
Zinc requirement for DNA replication in stimulated human lymphocytes.
Topics: Blood Proteins; Cations, Divalent; Cells, Cultured; Deoxycytidine; DNA Replication; Humans; Lectins; Leucine; Lymphocyte Activation; Lymphocytes; Nickel; Phenanthrolines; RNA; Thymidine; Time Factors; Tritium; Uridine; Zinc | 1973 |
The effect of inhibition of cytidine deaminase by tetrahydrouridine on the utilization of deoxycytidine and 5-bromodeoxycytidine for deoxyribonucleic acid synthesis.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Bone Marrow; Bromine; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; DNA, Neoplasm; Female; Fluorine; Intestine, Small; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Spleen; Testis; Tritium; Uridine | 1973 |
Exclusion of exogenous 5-methyl-2'-deoxycytidine from DNA in human leukemic cells. A study with [2(-14)C]- and [methyl-14C]5-methyl-2'-deoxycytidine.
Topics: 5-Methylcytosine; Cell Line; Cytosine; Deoxycytidine; DNA; Humans; Leucine; Leukemia, Lymphoid; RNA; Thymidine; Uridine | 1983 |
Marked radiosensitization of cells in culture to X ray by 5-chlorodeoxycytidine coadministered with tetrahydrouridine, and inhibitors of pyrimidine biosynthesis.
Topics: Animals; Aspartic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Radiation; Floxuridine; Humans; Laryngeal Neoplasms; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Tetrahydrouridine; Uridine | 1984 |
The problem of host DNA synthesis in murine cytomegalovirus-infected cells.
Topics: Animals; Cell Line; Cell Nucleus; Cytomegalovirus; Cytoplasm; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; Mice; Phosphates; Thymidine; Uridine | 1980 |
Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA.
Topics: Cytarabine; Deoxycytidine; DNA, Viral; HeLa Cells; Simplexvirus; Tetrahydrouridine; Uridine | 1981 |
Is ribonucleotide reductase in Ehrlich ascites mammary tumour cells the target of a growth inhibitor purified from bovine mammary gland?
Topics: Animals; Carcinoma, Ehrlich Tumor; Cattle; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyuridine; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Female; Growth Inhibitors; Hydroxyurea; Insulin; Mammary Glands, Animal; Mice; Nucleosides; Ribonucleotide Reductases; Uracil; Uridine | 1984 |
Purine nucleoside phosphorylase (PNP) deficiency: a therapeutic challenge.
Topics: B-Lymphocytes; Deoxycytidine; Erythrocytes; Follow-Up Studies; Guanine; Humans; Infant, Newborn; Lymphocyte Activation; Male; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; Ribonucleotides; T-Lymphocytes; Tetrahydrouridine; Uridine | 1984 |
Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cricetinae; Cricetulus; DCMP Deaminase; Deoxycytidine; DNA Replication; Drug Evaluation, Preclinical; Female; Humans; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Nucleotide Deaminases; Ovary; Tetrahydrouridine; Uridine | 1984 |
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine | 1983 |
Reversal of deamination-related cytotoxicity of 5-methyl-2'-deoxycytidine by tetrahydrouridine in human leukemia cells.
Topics: Biotransformation; Cell Line; Cell Survival; Deoxycytidine; Humans; Kinetics; Neoplasms; Tetrahydrouridine; Uridine | 1984 |
Uridine as the only alternative to pyrimidine de novo synthesis in rat T lymphocytes.
Topics: Amides; Animals; Concanavalin A; Cytidine Deaminase; Deoxycytidine; DNA; Lymphocyte Activation; Pyrazoles; Pyrimidines; Rats; Ribonucleosides; Ribose; T-Lymphocytes; Uridine | 1982 |
Erythrocyte nucleoside transport: asymmetrical binding of nitrobenzylthioinosine to nucleoside permeation sites.
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Cell Membrane Permeability; Deoxycytidine; Dipyridamole; Erythrocytes; Humans; Inosine; Kinetics; Nucleosides; Sheep; Thioinosine; Uridine | 1982 |
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Uridine | 1982 |
Synthesis of pyridazine analogues of the naturally occurring nucleosides cytidine, uridine, deoxycytidine, and deoxyuridine.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytidine; Deoxycytidine; Deoxyuridine; Hydrolysis; In Vitro Techniques; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Pyridazines; Pyrimidine Nucleosides; Uridine | 1982 |
Radioimmunoassays of plasma thymidine, uridine, deoxyuridine, and cytidine/deoxycytidine.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Immune Sera; Radioimmunoassay; Thymidine; Uridine | 1981 |
Nucleoside transport and metabolism in lymphocytes, polymorphonuclear cells and cerebral synaptosomes.
Topics: Adenosine; Animals; Biological Transport; Cerebral Cortex; Child; Deoxycytidine; Dilazep; Dipyridamole; DNA; Humans; Kinetics; Lymphocytes; Neutrophils; Nucleosides; Palatine Tonsil; Papaverine; Rats; Synaptosomes; Thioinosine; Thymidine; Uridine | 1994 |
Nucleotide metabolism in Lactococcus lactis: salvage pathways of exogenous pyrimidines.
Topics: Cytidine; Deoxycytidine; Deoxyuridine; Enzymes; Escherichia coli; Kinetics; Lactococcus lactis; Pyrimidines; Species Specificity; Uracil; Uridine | 1994 |
Seeking the nucleoside transporter.
Topics: Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Membrane; Cladribine; Cloning, Molecular; Cytarabine; Deoxycytidine; Erythrocytes; Gemcitabine; Glucose Transporter Type 1; Humans; Leukemia; Lymphoma; Membrane Proteins; Monosaccharide Transport Proteins; Nucleosides; Oocytes; Recombinant Proteins; Uridine; Vidarabine; Xenopus | 1997 |
Interaction of 2',2'-difluorodeoxycytidine (gemcitabine) and formycin B with the Na+-dependent and -independent nucleoside transporters of Ehrlich ascites tumor cells.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Carrier Proteins; Deoxycytidine; Formycins; Gemcitabine; Male; Membrane Proteins; Mice; Nucleoside Transport Proteins; Sodium; Thioinosine; Uridine | 1998 |
[3H]gemcitabine uptake by nucleoside transporters in a human head and neck squamous carcinoma cell line.
Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Carrier Proteins; Deoxycytidine; Drug Resistance; Formycins; Gemcitabine; Head and Neck Neoplasms; Humans; Membrane Proteins; Nucleoside Transport Proteins; Time Factors; Tritium; Tumor Cells, Cultured; Uridine | 1999 |
New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism.
Topics: Amino Acid Sequence; Chromatography; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Resistance; Models, Biological; Molecular Sequence Data; Phenotype; Phosphorylation; Point Mutation; Pyrimidines; Saccharomyces cerevisiae; Sequence Analysis, DNA; Substrate Specificity; Uridine; Uridine Kinase | 1999 |
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Cell Membrane; Deoxycytidine; Electrophysiology; Gemcitabine; Membrane Proteins; Neoplasms; Nucleosides; Oocytes; Recombinant Proteins; Sodium Channels; Uridine; Xenopus laevis | 1999 |
Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Carrier Proteins; Cytidine; Deoxycytidine; Electric Conductivity; Gemcitabine; Gene Expression; Humans; Membrane Potentials; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Oocytes; Sodium; Substrate Specificity; Uridine; Vidarabine; Xenopus laevis | 2000 |
An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.
Topics: Cyclization; Cytarabine; Cytidine; Deoxycytidine; Glycosylation; Molecular Structure; Organoselenium Compounds; Pyrimidine Nucleosides; Ribonucleosides; Selenium; Silicon; Stereoisomerism; Structure-Activity Relationship; Uridine; Vinyl Compounds | 2001 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. II. Incorporation of precursors.
Topics: Adenine; Animals; Carbon Radioisotopes; Cytidine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Mice; Nucleic Acid Precursors; Nucleosides; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Male; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Prostatic Neoplasms; Sequence Homology, Amino Acid; Sodium; Stereoisomerism; Tritium; Tumor Cells, Cultured; Uridine | 2001 |
A new method for the synthesis of oligodeoxyribonucleotides containing 4-N-alkoxycarbonyldeoxycytidine derivatives and their hybridization properties.
Topics: Adenosine; Alkaline Phosphatase; Animals; Base Sequence; Catalysis; Cattle; Chromatography, High Pressure Liquid; Deoxycytidine; DNA; Intestines; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Phosphodiesterase I; Phosphoric Diester Hydrolases; RNA; Snake Venoms; Thymidine; Uridine | 2002 |
Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.
Topics: Carbon Radioisotopes; Culture Techniques; Cytidine; Cytidine Deaminase; Cytosine; Cytosine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleosides; Enzymes; Multienzyme Complexes; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Phosphotransferases; Plant Stems; Pyrimidine Nucleosides; Pyrimidine Phosphorylases; Pyrimidines; Pyrimidinones; Solanum tuberosum; Thymidine; Thymidine Kinase; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate; Uridine Phosphorylase | 2002 |
Synthesis of the phosphoramidite derivative of 2'-deoxy-2'-C-beta-methylcytidine.
Topics: Cytidine; Deoxycytidine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Uridine | 2003 |
Synthesis of the phosphoramidite derivatives of 2'-deoxy-2'-C-alpha-methylcytidine and 2'-deoxy-2'-C-alpha-hydroxymethylcytidine: analogues for chemical dissection of RNA's 2'-hydroxyl group.
Topics: Cytidine; Deoxycytidine; Hydroxyl Radical; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; RNA; Uridine | 2004 |
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine | 2006 |
Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytosine; Deoxycytidine; Dioxolanes; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Nude; Mice, SCID; Pancreatic Neoplasms; Treatment Outcome; Tritium; Tumor Cells, Cultured; Uridine; Xenograft Model Antitumor Assays | 2007 |
Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer.
Topics: Adenocarcinoma; Adenoviridae; Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Survival; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Female; Gemcitabine; Genetic Vectors; Humans; Injections, Intralesional; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Protein Biosynthesis; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Uridine; Xenograft Model Antitumor Assays | 2008 |
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; In Vitro Techniques; Male; Perfusion; Phosphorylation; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine | 2009 |
Fishing in the (deoxyribonucleotide) pool.
Topics: Animals; Antimetabolites; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; Humans; Mitochondria; Mitochondrial Diseases; Models, Biological; Phosphorylation; Pyrimidine Nucleotides; Rats; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine | 2009 |
Erlotinib, gefitinib, and vandetanib inhibit human nucleoside transporters and protect cancer cells from gemcitabine cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Screening Assays, Antitumor; Drug Synergism; Erlotinib Hydrochloride; Gefitinib; Gemcitabine; Humans; Inhibitory Concentration 50; Nucleoside Transport Proteins; Piperidines; Quinazolines; Saccharomyces cerevisiae; Uridine | 2014 |
Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
Topics: Animals; Bacterial Proteins; Binding Sites; Biological Transport; Crystallography, X-Ray; Deoxycytidine; Female; Gemcitabine; Gene Expression; Humans; Kinetics; Membrane Transport Proteins; Molecular Docking Simulation; Nucleoside Transport Proteins; Oocytes; Protein Binding; Quantitative Structure-Activity Relationship; Recombinant Proteins; Ribavirin; Substrate Specificity; Thermodynamics; Uridine; Vibrio cholerae; Xenopus laevis | 2014 |
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer.
Topics: 5-Methylcytosine; Animals; Cell Death; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Nucleotides; Oxidation-Reduction; Phosphotransferases; Substrate Specificity; Up-Regulation; Uridine | 2015 |
Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Curcumin; Cyclohexanones; Deoxycytidine; Drug Interactions; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Pancreatic Neoplasms; Uridine | 2017 |
Core modified 8-17 DNAzymes with 2'-deoxy-2'-C-methylpyrimidine nucleosides.
Topics: Biocatalysis; Deoxycytidine; DNA, Catalytic; Molecular Structure; Uridine | 2020 |
Photocaged 5-(Hydroxymethyl)pyrimidine Nucleoside Phosphoramidites for Specific Photoactivatable Epigenetic Labeling of DNA.
Topics: 5-Methylcytosine; Deoxycytidine; DNA; Epigenesis, Genetic; Epigenomics; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Pyrimidine Nucleosides; Uracil; Uridine | 2020 |
Cytidine deaminases catalyze the conversion of
Topics: Cytidine; Cytidine Deaminase; Deoxycytidine; Pyrimidine Nucleosides; Uridine | 2023 |
Mycoplasma infection of cancer cells enhances anti-tumor effect of oxidized methylcytidines.
Topics: Cytidine Deaminase; Deoxycytidine; Humans; Mycoplasma Infections; Neoplasms; Tetrahydrouridine; Uridine | 2023 |