Page last updated: 2024-08-17

uridine and aspartic acid

uridine has been researched along with aspartic acid in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	53 (69.74)	18.7374
1990's	10 (13.16)	18.2507
2000's	9 (11.84)	29.6817
2010's	1 (1.32)	24.3611
2020's	3 (3.95)	2.80

Authors

Authors	Studies
Nakayama, H; Weser, E	1
Graff, JC; Plagemann, PG	1
Handschumacher, RE; Moyer, JD	1
Johnson, RK	1
Edmunds, NH; Kwong, LK; Tsuboi, KK	1
Chan, TC; Kuczek, T	1
Dröge, W; Gmünder, H; Roth, S	1
Martin, DS	1
Kemeny, NE; Martin, DS; Schneider, A	1
Chisena, CA; Cowan, KH; Cysyk, RL; Karle, JM	1
Chalmers, RA; Duffy, S; Harkness, RA; Jones, M; Purkiss, P	1
Cassady, JM; Jacobsen, LB; Morré, DJ; Putnam, JE; Sawick, DP	1
Chan, TC; Cleary, S; Howell, SB; Markman, M	2
Chan, TC; Howell, SB; King, ME; Taetle, R; Young, B	1
Chan, TC; Howell, SB	1
Handmaker, SD; Kay, JE	1
DeBusk, AG; Rao, TK	1
Plagemann, PG	1
Olszowy, J; Switzer, RL; White, MN	1
Olszowy, J; Switzer, RL	1
Gülen, S; Smith, PC; Tremblay, GC	1
Seaver, SS; Stark, GR; Swyryd, EA	1
Davis, JR; Hollinger, MA	1
Moscona, AA; Sarkar, PK	1
Gerhart, JC; O'Donovan, GA	1
Beebe, JL	1
Dunn, JH; Herrmann, EC; Schmidt, RR	1
Ito, K; Uchino, H	1
Green, H; Ishii, K	1
Knott, CE; Smith, PC; Tremblay, GC	1
Atkinson, PH; Ceccarini, C; Muramatsu, T; Nathenson, SG	1
Herbert, JA; Teekell, RA; Watts, AB	1
Bourget, PA; Tremblay, GC	1
Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N	1
Galofré, A; Kretchmer, N	1
Bresnick, E; Burleson, SS	1
Frost, P; Giegel, JL; Stolfi, LM; Weinstein, GD	1
Hempstead, KW; Kopp, LE; Miech, RP; Santos, JN	1
Atkins, LM; Gale, GR; Ostrander, WE	1
Gale, GR; Schmidt, GB	1
Appel, SH; Silberberg, DH	1
Groth, DP; Jiang, N	1
Burns, VW	1
Cadman, E; Grant, S; Jakubowski, A; Rauscher, F	1
Anukarahanonta, T; Holstege, A; Keppler, DO	1
Anderson, LW; Cysyk, RL; Dietrick, DD; Karle, JM	1
Briggle, TV; Greer, S; Mekras, JA; Perez, LM	1
de Saint Vincent, BR; Delbrück, S; Eckhart, W; Meinkoth, J; Vitto, L; Wahl, G	1
Anderson, LW; Cysyk, RL; Karle, JM	1
Lankelma, J; Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM	1
Martin, DS; Sawyer, RC; Spiegelman, S; Stolfi, RL; Young, CW	1
Golovinsky, E; Spassova, M	1
Casper, ES; Gralla, RJ; Kemeny, N; Wiley, RG	1
Handschumacher, RE; Moyer, JD; Oliver, JT	1
Brinster, RL; Troike, DE	1
Anderson, LW; Cysyk, RL; Erlichman, C; Karle, JM	1
Allegra, CJ; Grogan, L; Sotos, GA	1
Bodlaender, JM; Slingerland, RJ; Van Gennip, AH; Van Kuilenburg, AB; Voûte, PA	1
Colofiore, J; Kemeny, N; Martin, D; Sawyer, R; Schneider, A; Seiter, K; Williams, L	1
Blough, HA; Grem, JL; Katsafanas, GC; Moss, B	1
Davidson, JN; Qiu, Y	1
Huang, Q; Lau, SS; Monks, TJ	1
Foster, PG; Huang, L; Santi, DV; Stroud, RM	1
Aertsen, A; Balzarini, J; Camarasa, MJ; De Clercq, E; Pelemans, H; Pérez-Pérez, MJ; San-Félix, A; Van Laethem, K; Vandamme, AM; Velázquez, S	1
Rana, TM; Shah, K; Wang, Z	1
Behm-Ansmant, I; Branlant, C; Grosjean, H; Massenet, S; Motorin, Y	1
Ginter, JM; Hamilton, CS; Johnston, MV; Mueller, EG; Spedaliere, CJ	1
Sievers, A; Wolfenden, R	1
Garcia, RA; Gonzalez, A; Hu, Z; Liu, L; Saydoff, JA; von Borstel, RW	1
Kemeny, NE; Leonard, GD	1
Chan, CM; Huang, RH	1
Chen, J; McDonald, MK; Miracco, EJ; Mueller, EG; Xie, Y	1
Kagra, D; Preethi, SP; Sharma, P	1
Bangarbale, S; Bansal, S; Ecelbarger, CM; Jayatilake, MM; Kurtz, R; Levi, M; Shepard, BD	1
Wang, Z; Wu, X; Zhang, Y; Zhou, T	1

Reviews

3 review(s) available for uridine and aspartic acid

Article	Year
Analogs of pyrimidine and purine mononucleotide precursors as metabolic inhibitors. Pharmacology & therapeutics, 1981, Volume: 13, Issue:3 Topics: Animals; Antimetabolites; Aspartic Acid; Imidazoles; Orotic Acid; Purine Nucleosides; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Triazoles; Uridine	1981
Preclinical and clinical aspects of biomodulation of 5-fluorouracil. Cancer treatment reviews, 1994, Volume: 20, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine	1994
The roles of the essential Asp-48 and highly conserved His-43 elucidated by the pH dependence of the pseudouridine synthase TruB. Archives of biochemistry and biophysics, 2005, Jan-01, Volume: 433, Issue:1 Topics: Aspartic Acid; Base Pairing; Binding Sites; Catalysis; Escherichia coli; Escherichia coli Proteins; Genetic Variation; Histidine; Hydrogen-Ion Concentration; Intramolecular Lyases; Intramolecular Transferases; Kinetics; Models, Molecular; Models, Structural; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Substrate Specificity; Tyrosine; Uridine	2005

Other Studies

73 other study(ies) available for uridine and aspartic acid

Article	Year
Pyrimidine biosynthetic enzymes in rat intestine after small bowel resection. Gastroenterology, 1975, Volume: 68, Issue:3 Topics: Adaptation, Physiological; Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Radioisotopes; DNA; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Orotic Acid; Phosphotransferases; Pyrimidines; Rats; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine	1975
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate. Cancer research, 1976, Volume: 36, Issue:4 Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Glucose; Hypoxanthines; Inosine Nucleotides; Liver Neoplasms; Mengovirus; Neoplasm Proteins; Neoplasms, Experimental; Nitroso Compounds; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Neoplasm; Succinates; Uracil Nucleotides; Uridine	1976
Selective inhibition of pyrimidine synthesis and depletion of nucleotide pools by N-(phosphonacetyl)-L-aspartate. Cancer research, 1979, Volume: 39, Issue:8 Topics: Animals; Aspartic Acid; Cells, Cultured; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Pyrimidines; Ribonucleosides; Uridine	1979
Reversal of toxicity and antitumor activity of N-(phosphonacetyl)-L-aspartate by uridine or carbamyl-DL-asparate in vivo. Biochemical pharmacology, 1977, Jan-01, Volume: 26, Issue:1 Topics: Animals; Antineoplastic Agents; Aspartic Acid; Body Weight; Carbamates; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine	1977
Selective inhibition of pyrimidine biosynthesis and effect on proliferative growth of colonic cancer cells. Cancer research, 1977, Volume: 37, Issue:9 Topics: Animals; Aspartic Acid; Cell Division; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Humans; Kinetics; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrimidines; Transplantation, Isogeneic; Uridine	1977
Mechanism-based model for tumor drug resistance. Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5 Topics: Animals; Aspartic Acid; Cell Cycle; Cell Survival; Dipyridamole; Dose-Response Relationship, Drug; Drug Resistance; Models, Biological; Models, Statistical; Phosphonoacetic Acid; Pyrimidines; Tumor Cells, Cultured; Uridine	1992
Regulation of intracellular glutathione levels and lymphocyte functions by lactate. Cellular immunology, 1991, Volume: 136, Issue:1 Topics: Animals; Aspartic Acid; DNA; Glutathione; Interleukin-2; Lactates; Lactic Acid; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Uridine	1991
Introduction to 5-fluorouracil modulation. Cancer investigation, 1990, Volume: 8, Issue:2 Topics: Antimetabolites, Antineoplastic; Aspartic Acid; Drug Interactions; Fluorouracil; Humans; Leucovorin; Methotrexate; Phosphonoacetic Acid; Uridine	1990
Phase I trial of PALA, methotrexate, fluorouracil, leucovorin, and uridine rescue in patients with advanced cancer. The use of uridine to decrease fluorouracil toxicity. Cancer investigation, 1990, Volume: 8, Issue:2 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms; Phosphonoacetic Acid; Uridine	1990
Uracil nucleotide synthesis in a human breast cancer cell line (MCF-7) and in two drug-resistant sublines that contain increased levels of enzymes of the de novo pyrimidine pathway. Molecular pharmacology, 1986, Volume: 30, Issue:2 Topics: Amides; Aspartate Carbamoyltransferase; Aspartic Acid; Breast Neoplasms; Carbamoyl-Phosphate Synthase (Ammonia); Cell Line; Dihydroorotase; Drug Resistance; Female; Humans; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Uracil Nucleotides; Uridine	1986
The effects of fetal energy depletion on amniotic fluid concentrations of amino acids, organic acids and related metabolites. Journal of inherited metabolic disease, 1988, Volume: 11, Issue:1 Topics: Adenosine Triphosphate; Amino Acids; Amniotic Fluid; Arginine; Aspartic Acid; Asphyxia Neonatorum; Diagnosis, Differential; Female; Fetus; Humans; Hypoxanthine; Hypoxanthines; Infant, Newborn; Metabolism, Inborn Errors; Ornithine; Pregnancy; Uridine	1988
Pyrimidine nucleosides enhance the efficacy of inhibitors of pyrimidine biosynthesis in cultured hepatocellular carcinoma cells. Life sciences, 1988, Volume: 42, Issue:8 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aspartic Acid; Cell Division; Cytidine; Liver Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrimidine Nucleosides; Pyrimidines; Rats; Tumor Cells, Cultured; Uridine	1988
Plasma uridine changes in cancer patients treated with the combination of dipyridamole and N-phosphonacetyl-L-aspartate. Cancer research, 1986, Volume: 46, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Dipyridamole; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine	1986
Phase I trial of combination therapy of cancer with N-phosphonacetyl-L-aspartic acid and dipyridamole. Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Dipyridamole; Drug Evaluation; Drug Synergism; Female; Gastrointestinal Diseases; Headache; Humans; Male; Middle Aged; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine	1987
Modulation of the activity of PALA by dipyridamole. Cancer treatment reports, 1985, Volume: 69, Issue:4 Topics: Animals; Aspartic Acid; Biological Transport; Cell Line; Colonic Neoplasms; Dipyridamole; Drug Interactions; Humans; In Vitro Techniques; Lethal Dose 50; Leukemia, Myeloid; Melanoma; Mice; Mice, Nude; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrimidine Nucleosides; Tritium; Uridine	1985
Mechanism of synergy between N-phosphonacetyl-L-aspartate and dipyridamole in a human ovarian carcinoma cell line. Cancer research, 1985, Volume: 45, Issue:8 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cell Line; Dipyridamole; Drug Synergism; Female; Humans; Nucleotides; Organophosphorus Compounds; Ovarian Neoplasms; Phosphonoacetic Acid; Uridine	1985
Uridine incorporation and RNA synthesis during stimulation of lymphocytes by PHA. Experimental cell research, 1970, Volume: 63, Issue:2 Topics: Aspartic Acid; Cycloheximide; Dactinomycin; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Orotic Acid; Phosphotransferases; Prostaglandins; RNA; Stimulation, Chemical; Time Factors; Tritium; Uridine	1970
Characteristics of a transport-deficient mutant (nap) of Neurospora crassa. Biochimica et biophysica acta, 1973, Nov-16, Volume: 323, Issue:4 Topics: Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport, Active; Carbon Radioisotopes; Chromatography, Affinity; Cyanogen Bromide; Glucose; Glycoproteins; Kinetics; Membrane Transport Proteins; Methionine; Mutation; Neurospora; Neurospora crassa; Phenylalanine; Protein Binding; Time Factors; Uridine	1973
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle. Journal of cellular physiology, 1971, Volume: 77, Issue:2 Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Culture Media; Culture Techniques; Diffusion; DNA; Electrophoresis; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium; Uracil; Uridine	1971
Regulation and mechanism of phosphoribosylpyrophosphate synthetase: repression by end products. Journal of bacteriology, 1971, Volume: 108, Issue:1 Topics: Adenine; Adenosine; Adenosine Triphosphate; Aspartic Acid; Cell-Free System; Culture Media; Enzyme Repression; Fluorometry; Histidine; Nucleotides; Oxidoreductases; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Phosphotransferases; Salmonella typhimurium; Transferases; Tryptophan; Uridine	1971
Specific repression of phosphoribosylpyrophosphate synthetase by uridine compounds in Salmonella typhimurium. Journal of bacteriology, 1972, Volume: 110, Issue:1 Topics: Adenosine Triphosphate; Aspartic Acid; Carbamates; Cytidine; Enzyme Repression; Genetics, Microbial; Mutation; Pentosephosphates; Phosphoric Acids; Phosphotransferases; Salmonella typhimurium; Transferases; Uridine	1972
Evidence from the control of pyrimidine biosynthesis in tissue minces by purines. Biochemical and biophysical research communications, 1974, Feb-27, Volume: 56, Issue:4 Topics: Adenosine; Animals; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Chickens; Guanosine; In Vitro Techniques; Male; Mammary Glands, Animal; Organ Specificity; Organophosphorus Compounds; Orotic Acid; Oviducts; Phosphotransferases; Rats; Time Factors; Uridine	1974
N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture. The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21 Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Ion Exchange; Fibroblasts; Haplorhini; Kidney; Kinetics; Mice; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Simian virus 40; Species Specificity; Time Factors; Tritium; Uridine	1974
Aerobic metabolism of uniformly labelled [14C]glucose in tissue slices of rat testis. Journal of reproduction and fertility, 1968, Volume: 17, Issue:2 Topics: Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Chromatography, Ion Exchange; Cryptorchidism; Culture Techniques; Glucose; Glutamates; Glutamine; Ketoglutaric Acids; Lactates; Male; Oxygen; Protein Biosynthesis; Rats; Spermatozoa; Testis; Uridine	1968
Changes in macromolecular synthesis associated with the induction of glutamine synthetase in embryonic retina. Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:9 Topics: Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Chick Embryo; Cytarabine; Enzyme Induction; Glutamate-Ammonia Ligase; Hydrocortisone; Macromolecular Substances; Protein Biosynthesis; Proteins; Retina; Ribosomes; Tritium; Uridine	1971
Isolation and partial characterization of regulatory mutants of the pyrimidine pathway in Salmonella typhimurium. Journal of bacteriology, 1972, Volume: 109, Issue:3 Topics: Aspartic Acid; Centrifugation, Density Gradient; Chromosome Mapping; Culture Media; Cytosine Nucleotides; Drug Resistance, Microbial; Feedback; Fluorine; Fluorouracil; Genetics, Microbial; Mutation; Nucleotides; Orotic Acid; Oxidoreductases; Phosphorus; Phosphorus Isotopes; Pyrimidines; Salmonella typhimurium; Transduction, Genetic; Transferases; Uridine	1972
Transport alterations in a phosphatidylethanolamine-deficient mutant of Bacillus subtilis. Journal of bacteriology, 1972, Volume: 109, Issue:2 Topics: Acetates; Adenosine; Amino Acids; Aspartic Acid; Bacillus subtilis; Biological Transport, Active; Carbon Isotopes; Cell Membrane; Culture Media; Genetics, Microbial; Glucose; Lysine; Mutation; Phosphatidylethanolamines; Pyruvates; Stereoisomerism; Thymine; Time Factors; Uracil; Uridine	1972
DEAE paper chromatography to separate intermediates of the pyrimidine biosynthetic pathway and to assay asparatate transcarbamylase and dihydroorotase activities. Analytical biochemistry, 1973, Volume: 53, Issue:2 Topics: Amidohydrolases; Aspartate Carbamoyltransferase; Aspartic Acid; Autoradiography; Carbamates; Carbon Isotopes; Chlorella; Chlorophyta; Chromatography, DEAE-Cellulose; Chromatography, Paper; Kinetics; Methods; Nucleotides; Orotic Acid; Uridine	1973
Control of pyrimidine biosynthesis in human lymphocytes. Inhibition of pyrimidine biosynthesis de novo in phytohemagglutinin-stimulated lymphocytes by external uridine and its inhibition mechanism. The Journal of biological chemistry, 1973, Jul-10, Volume: 248, Issue:13 Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Azauridine; Bicarbonates; Carbamates; Carbon Dioxide; Carbon Isotopes; Humans; Lectins; Lymphocytes; Nucleic Acids; Phosphoric Acids; Phosphotransferases; Pyrimidines; Tritium; Uracil Nucleotides; Uridine	1973
Lethality of adenosine for cultured mammalian cells by interference with pyrimidine biosynthesis. Journal of cell science, 1973, Volume: 13, Issue:2 Topics: Adenosine; Animals; Aspartic Acid; Carbon Radioisotopes; Cattle; Cell Line; Cells, Cultured; Chromatography; Nucleotides; Pyrimidines; Uridine	1973
Detection of the feedback control of pyrimidine biosynthesis in slices of several rat tissues. Biochemical and biophysical research communications, 1973, Dec-19, Volume: 55, Issue:4 Topics: Animals; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Depression, Chemical; Feedback; Female; Kidney; Liver; Mammary Glands, Animal; Organophosphorus Compounds; Orotic Acid; Pyrimidines; Rats; Spleen; Uridine	1973
Cell-surface glycopeptides: growth-dependent changes in the carbohydrate-peptide linkage region. Journal of molecular biology, 1973, Nov-15, Volume: 80, Issue:4 Topics: Aspartic Acid; Binding Sites; Carbon Radioisotopes; Cell Count; Cell Membrane; Cells, Cultured; Chromatography; Electrophoresis; Fucose; Galactose; Glucosidases; Glycopeptides; Hexosamines; Humans; In Vitro Techniques; Mannose; Molecular Weight; Pronase; Tritium; Uridine	1973
Effect of amino acids on liver RNA synthesis in the chick. The Journal of nutrition, 1972, Volume: 102, Issue:8 Topics: Amino Acids; Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Chickens; Diet; Folic Acid; Glutamine; Glycine; Liver; Protein Biosynthesis; RNA; Tritium; Tryptophan; Uridine	1972
Control of pyrimidine biosynthesis in rat liver by feedback inhibition of aspartate carbamoyltransferase. Biochemical and biophysical research communications, 1972, Jan-31, Volume: 46, Issue:2 Topics: Animals; Aspartic Acid; Bicarbonates; Carbamates; Carbon Isotopes; Feedback; Kinetics; Liver; Orotic Acid; Phosphoric Acids; Pyrimidines; Rats; Transferases; Uridine	1972
Serine requirement in leukemic and normal blood cells. Science (New York, N.Y.), 1969, Mar-28, Volume: 163, Issue:3874 Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine	1969
Biosynthesis of pyrimidines by various organs of the chick during embryogenesis. Pediatric research, 1970, Volume: 4, Issue:1 Topics: Amidohydrolases; Animals; Aspartic Acid; Brain; Chick Embryo; DNA; Intestines; Liver; Myocardium; Orotic Acid; Phosphotransferases; Pyrimidines; Transferases; Uridine	1970
Rates of turnover of deoxythymidine kinase and of its template RNA in Novikoff hepatoma and neonatal liver. Cancer research, 1970, Volume: 30, Issue:4 Topics: Animals; Animals, Newborn; Ascitic Fluid; Aspartic Acid; Carbon Isotopes; Cycloheximide; Dactinomycin; Deoxyribonucleosides; Hematoma; Liver; Male; Neoplasms, Experimental; Phosphotransferases; Protein Biosynthesis; Puromycin; Rats; RNA; Templates, Genetic; Thymidine; Time Factors; Uridine	1970
Androgenic regulation of nucleic acid and protein synthesis in the hamster flank organ and other tissues. Endocrinology, 1971, Volume: 89, Issue:3 Topics: Amino Acids; Androgens; Animals; Aspartic Acid; Carbon Isotopes; Castration; Cricetinae; DNA; Male; Methionine; Prostate; Protein Biosynthesis; Proteins; RNA; Sebaceous Glands; Seminal Vesicles; Stimulation, Chemical; Testosterone; Thymidine; Tritium; Uridine	1971
Nucleotide metabolism in rat brain. Journal of neurochemistry, 1968, Volume: 15, Issue:5 Topics: Adenine; Animals; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Chromatography, Paper; DNA; Glucosyltransferases; Glycine; Guanine; Hypoxanthines; In Vitro Techniques; Nerve Tissue Proteins; Nucleosides; Nucleotides; Orotic Acid; Oxidoreductases; Phosphotransferases; Rats; RNA; Uridine; Xanthine Oxidase; Xanthines	1968
Effects of alanosine on purine and pyrimidine synthesis. Biochemical pharmacology, 1968, Volume: 17, Issue:9 Topics: Aspartic Acid; Candida; Carbon Isotopes; Formates; Propionates; Purines; Pyrimidines; RNA; Tritium; Uridine	1968
Mode of action of alanosine. Biochemical pharmacology, 1968, Volume: 17, Issue:3 Topics: Adenine; Animals; Antifungal Agents; Antiviral Agents; Aspartic Acid; Azaserine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Depression, Chemical; Formates; Glutamine; Glycine; Guanine; Leucine; Nitrosamines; Nucleotides; Propionates; RNA, Neoplasm; Thymidine; Tritium; Uridine	1968
Pyrimidine synthesis in tissue culture. Journal of neurochemistry, 1968, Volume: 15, Issue:12 Topics: Animals; Aspartic Acid; Bicarbonates; Brain; Carbon Isotopes; Cerebellum; Chromatography, Thin Layer; Citrulline; Culture Techniques; Ligases; Liver; Orotic Acid; Pyrimidines; Rats; RNA; Sodium; Spectrum Analysis; Triazines; Tritium; Uridine	1968
The role of deoxyribose 5-phosphate aldolase in the synthesis of deoxyribonucleotide in mammalian cells. Biochemical and biophysical research communications, 1966, Jan-04, Volume: 22, Issue:1 Topics: Adenine; Aldehyde-Lyases; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA; Glycine; In Vitro Techniques; Liver; Liver Regeneration; Mice; Nucleotides; Orotic Acid; Protein Biosynthesis; Rats; RNA; Subcellular Fractions; Threonine; Thymidine; Uridine	1966
Effects of sonic irradiation on yeast. Radiation research. Supplement, 1967, Volume: 7 Topics: Aspartic Acid; Carbon Isotopes; Cell Membrane Permeability; Histidine; Saccharomyces; Succinates; Temperature; Ultrasonics; Uridine; Viscosity	1967
Effect of N-(phosphonacetyl)-L-aspartate on 5-azacytidine metabolism in P388 and L1210 cells. Cancer research, 1981, Volume: 41, Issue:2 Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Azacitidine; Cell Division; Cytidine; DNA, Neoplasm; Leukemia L1210; Leukemia, Experimental; Mice; Neoplasm Proteins; Organophosphorus Compounds; Phosphonoacetic Acid; RNA, Neoplasm; Uridine	1981
Selective enhancement of 5-fluorouridine uptake and action in rat hepatomas in vivo following pretreatment with D-galactosamine and 6-azauridine or N-(phosphonacetyl)-L-aspartate. European journal of cancer, 1980, Volume: 16, Issue:9 Topics: Animals; Aspartic Acid; Azauridine; DNA, Neoplasm; Drug Therapy, Combination; Female; Galactosamine; Liver; Liver Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Rats; RNA, Neoplasm; Stimulation, Chemical; Uracil Nucleotides; Uridine	1980
Effect of inhibitors of the de novo pyrimidine biosynthetic pathway on serum uridine levels in mice. Cancer research, 1981, Volume: 41, Issue:12 Pt 1 Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Azauridine; Galactosamine; Liver; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Uridine	1981
Marked radiosensitization of cells in culture to X ray by 5-chlorodeoxycytidine coadministered with tetrahydrouridine, and inhibitors of pyrimidine biosynthesis. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Aspartic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Radiation; Floxuridine; Humans; Laryngeal Neoplasms; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Tetrahydrouridine; Uridine	1984
The cloning and reintroduction into animal cells of a functional CAD gene, a dominant amplifiable genetic marker. Cell, 1981, Volume: 27, Issue:2 Pt 1 Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Cloning, Molecular; Cricetinae; Cricetulus; Dihydroorotase; DNA, Recombinant; Drug Resistance; Female; Gene Amplification; Genes, Dominant; Genetic Markers; Genetic Vectors; Multienzyme Complexes; Ovary; Phosphonoacetic Acid; Proteins; Transformation, Genetic; Uridine	1981
Effect of plasma concentrations of uridine on pyrimidine biosynthesis in cultured L1210 cells. The Journal of biological chemistry, 1984, Jan-10, Volume: 259, Issue:1 Topics: Animals; Aspartic Acid; Bicarbonates; Culture Media; Leukemia L1210; Mice; Phosphonoacetic Acid; Pyrimidines; Sodium Bicarbonate; Uracil Nucleotides; Uridine	1984
Separation of several 5-fluorouracil metabolites in various melanoma cell lines. Evidence for the synthesis of 5-fluorouracil-nucleotide sugars. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:11 Topics: Animals; Aspartic Acid; Cell Line; Cells, Cultured; Chromatography; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Humans; Melanoma; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil Nucleotides; Uridine; Uridine Triphosphate	1984
Improved therapeutic index with sequential N-phosphonacetyl-L-aspartate plus high-dose methotrexate plus high-dose 5-fluorouracil and appropriate rescue. Cancer research, 1983, Volume: 43, Issue:10 Topics: Animals; Antineoplastic Agents; Aspartic Acid; Drug Therapy, Combination; Female; Fluorouracil; Leucovorin; Male; Methotrexate; Mice; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine	1983
Neurotoxicity of the pyrimidine synthesis inhibitor N-phosphonoacetyl-L-aspartate. Annals of neurology, 1982, Volume: 12, Issue:2 Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Brain Diseases; Disease Models, Animal; Epilepsy; Female; Humans; Male; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Rats; Rats, Inbred Strains; Seizures; Uridine	1982
Salvage of circulating pyrimidine nucleosides in the rat. Cancer research, 1981, Volume: 41, Issue:8 Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cytidine; Male; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Rats; Ribonucleosides; Ribose; Tissue Distribution; Uridine	1981
De novo pyrimidine nucleotide synthesis in the preimplantation mouse embryo. Experimental cell research, 1981, Volume: 134, Issue:2 Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Blastocyst; Mice; Morula; Orotic Acid; Phosphonoacetic Acid; Pyrimidine Nucleotides; Uridine	1981
Serum uridine levels in patients receiving N-(phosphonacetyl)-L-aspartate. Cancer research, 1980, Volume: 40, Issue:8 Pt 1 Topics: Antimetabolites, Antineoplastic; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Humans; Melanoma; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine	1980
Quantitative analysis of the pyrimidine metabolism in pheochromocytoma PC-12 cells. European journal of biochemistry, 1995, Oct-15, Volume: 233, Issue:2 Topics: Animals; Aspartic Acid; Cytidine; PC12 Cells; Rats; Uridine	1995
Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin. Cancer, 1993, Mar-01, Volume: 71, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasms; Phosphonoacetic Acid; Stomatitis; Uridine	1993
Inhibition of vaccinia virus replication by N-(phosphonoacetyl)-L-aspartate: differential effects on viral gene expression result from a reduced pyrimidine nucleotide pool. Virology, 1997, Sep-15, Volume: 236, Issue:1 Topics: Antiviral Agents; Aspartic Acid; Cell Survival; Cytidine Triphosphate; DNA-Directed RNA Polymerases; Gene Expression Regulation, Viral; HeLa Cells; Humans; Kinetics; Macromolecular Substances; Phosphonoacetic Acid; Pyrimidine Nucleotides; RNA, Messenger; Transcription, Genetic; Uridine; Uridine Triphosphate; Vaccinia virus; Virus Replication	1997
CAD overexpression in mammalian cells. Advances in experimental medicine and biology, 1998, Volume: 431 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Division; Cell Line; Cloning, Molecular; Cricetinae; Dihydroorotase; Molecular Sequence Data; Multienzyme Complexes; Phosphonoacetic Acid; Recombinant Proteins; Transfection; Uridine	1998
Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine. The Biochemical journal, 1999, Jul-01, Volume: 341 ( Pt 1) Topics: Animals; Aspartic Acid; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Culture Media; Cytidine; Cytidine Triphosphate; Diazooxonorleucine; DNA Damage; DNA-Binding Proteins; Epithelial Cells; Gene Expression Regulation; Glutamine; Isoxazoles; Ketoglutaric Acids; Kidney Tubules, Proximal; RNA, Messenger; Salts; Swine; Transcription Factor CHOP; Transcription Factors; Uridine	1999
The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I. Nature structural biology, 2000, Volume: 7, Issue:1 Topics: Amino Acid Sequence; Anticodon; Aspartic Acid; Binding Sites; Conserved Sequence; Crystallization; Crystallography, X-Ray; Dimerization; Escherichia coli; Hydro-Lyases; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudouridine; RNA-Binding Proteins; RNA, Transfer; Substrate Specificity; Uridine	2000
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138. Virology, 2001, Feb-01, Volume: 280, Issue:1 Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine	2001
Probing Tat peptide-TAR RNA interactions by psoralen photo-cross-linking. Biochemistry, 2001, May-29, Volume: 40, Issue:21 Topics: Amino Acid Sequence; Aspartic Acid; Cross-Linking Reagents; Cysteine; Ficusin; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Humans; Molecular Sequence Data; Peptide Fragments; Photochemistry; Pyrones; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus; Threonine; Uridine	2001
Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae. The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51 Topics: Amino Acid Sequence; Aminohydrolases; Aspartic Acid; Catalysis; Cell-Free System; Cytoplasm; Dose-Response Relationship, Drug; Gene Deletion; Genetic Complementation Test; Intramolecular Transferases; Mitochondria; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Open Reading Frames; Plasmids; Protein Structure, Tertiary; Recombinant Proteins; RNA; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Uridine	2004
The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase. Bioorganic chemistry, 2005, Volume: 33, Issue:1 Topics: Alanine; Aspartic Acid; Binding, Competitive; Decarboxylation; Molecular Structure; Mutation; Orotidine-5'-Phosphate Decarboxylase; Phosphates; Saccharomyces cerevisiae; Substrate Specificity; Time Factors; Uridine	2005
Severe cytochrome c oxidase inhibition in vivo does not induce a pyrimidine deficiency; neuroprotective action of oral uridine prodrug PN401 requires supraphysiological levels of uridine. Brain research, 2005, Dec-20, Volume: 1066, Issue:1-2 Topics: Acetates; Animals; Apoptosis; Aspartic Acid; Azides; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex IV; Enzyme Inhibitors; Fibroblasts; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Phosphonoacetic Acid; Prodrugs; Pyrimidines; Uridine	2005
Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases. Diseases of the colon and rectum, 2006, Volume: 49, Issue:3 Topics: Acetates; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Humans; Immunologic Factors; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Remission Induction; Uridine; Vitamin B Complex	2006
Enzymatic characterization and mutational studies of TruD--the fifth family of pseudouridine synthases. Archives of biochemistry and biophysics, 2009, Volume: 489, Issue:1-2 Topics: Aspartic Acid; Catalysis; Escherichia coli; Escherichia coli Proteins; Hydro-Lyases; Intramolecular Transferases; Isomerism; Mutation; Tyrosine; Uridine	2009
The handling of the mechanistic probe 5-fluorouridine by the pseudouridine synthase TruA and its consistency with the handling of the same probe by the pseudouridine synthases TruB and RluA. Biochemistry, 2011, Jan-25, Volume: 50, Issue:3 Topics: Aspartic Acid; Escherichia coli Proteins; Esters; Hydrolysis; Intramolecular Transferases; Molecular Probes; Nucleosides; RNA; Uridine	2011
Interaction of aspartic acid and asparagine with RNA nucleobases: a quantum chemical view. Journal of biomolecular structure & dynamics, 2020, Volume: 38, Issue:3 Topics: Adenosine; Asparagine; Aspartic Acid; Binding Sites; Cytidine; Guanidine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Quantum Theory; RNA; Thermodynamics; Uridine	2020
Renal Metabolome in Obese Mice Treated with Empagliflozin Suggests a Reduction in Cellular Respiration. Biomolecules, 2022, 08-25, Volume: 12, Issue:9 Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Cell Respiration; Flavin Mononucleotide; Glucosides; Kidney; Male; Metabolome; Mice; Mice, Obese; Phosphatidic Acids; Phosphatidylcholines; Phosphoenolpyruvate; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Spermidine; Spermine; Succinates; Urea; Uridine	2022
N-carbamoyl aspartate reduced body weight by stimulating the thermogenesis of iBAT. Biochemical and biophysical research communications, 2023, 07-12, Volume: 665 Topics: Adipose Tissue, Brown; Animals; Aspartic Acid; Body Weight; Diet, High-Fat; Mice; Pyrimidines; Thermogenesis; Uridine	2023