Compounds > uridine
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uridine and 1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)

uridine has been researched along with 1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balzarini, J; Bohman, C; Camarasa, MJ; De Clercq, E; Naesens, L; Pérez-Pérez, MJ; San-Félix, A1
Alvarez, R; Balzarini, J; Camarasa, MJ; Gago, F; Jimeno, ML; Pérez-Pérez, MJ1
Aertsen, A; Balzarini, J; Camarasa, MJ; De Clercq, E; Pelemans, H; Pérez-Pérez, MJ; San-Félix, A; Van Laethem, K; Vandamme, AM; Velázquez, S1
Anderson, JN; Balzarini, J; Camarasa, MJ; De Clercq, E; Karlsson, A; Pérez-Pérez, MJ; Perno, CF; San-Félix, A; Velázquez, S1
Camarasa, MJ; Pérez-Pérez, MJ; San-Félix, A; Velázquez, S1

Reviews

1 review(s) available for uridine and 1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)

ArticleYear
TSAO derivatives the first non-peptide inhibitors of HIV-1 RT dimerization.
    Antiviral chemistry & chemotherapy, 2005, Volume: 16, Issue:3

    Topics: Anti-HIV Agents; Dimerization; HIV Reverse Transcriptase; Humans; Organosilicon Compounds; Reverse Transcriptase Inhibitors; Spiro Compounds; Thymidine; Uridine

2005

Other Studies

4 other study(ies) available for uridine and 1-(2',5'-bis-o-(tert-butyldimethylsilylribofuranosyl)-3-n-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)

ArticleYear
Metabolism and pharmacokinetics of the anti-HIV-1-specific inhibitor [1-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3-N- methyl-thymine]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dio xide).
    Biochemical pharmacology, 1993, Jul-06, Volume: 46, Issue:1

    Topics: Animals; Antiviral Agents; CD4-Positive T-Lymphocytes; Cell Line; Half-Life; HIV-1; Humans; Metabolic Clearance Rate; Mice; Models, Chemical; Spiro Compounds; Thymidine; Thymidine Kinase; Thymidine Phosphorylase; Tissue Distribution; Tritium; Uridine

1993
Novel 3'-spiro nucleoside analogues of TSAO-T. Part II. A comparative study based on NMR conformational analysis in solution and theoretical calculations.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:4

    Topics: Anti-HIV Agents; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Nucleosides; Reverse Transcriptase Inhibitors; Spiro Compounds; Static Electricity; Thymidine; Uridine

1998
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
    Virology, 2001, Feb-01, Volume: 280, Issue:1

    Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine

2001
Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV.
    Journal of virology, 2001, Volume: 75, Issue:13

    Topics: Anti-HIV Agents; Antimetabolites; Deoxycytosine Nucleotides; Drug Resistance, Microbial; Genome, Viral; HIV Reverse Transcriptase; HIV-1; Reverse Transcriptase Inhibitors; Spiro Compounds; Thymidine; Thymine Nucleotides; Uridine

2001