uric acid has been researched along with triazoles in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.14) | 18.7374 |
| 1990's | 1 (2.38) | 18.2507 |
| 2000's | 3 (7.14) | 29.6817 |
| 2010's | 32 (76.19) | 24.3611 |
| 2020's | 3 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Chance, B; Oshino, N | 1 |
| Baer, JE; Baldwin, JJ; Duggan, DE; Noll, RM; Novello, FC | 1 |
| Bergmann, F; Kwietny-Govrin, H; Ungar-Waron, H | 1 |
| Egido, J; González, E; Gutierrez, S; Herrero-Beaumont, G; Miguélez, R; Navarro, F; Palacios, I; Sanchez-Pernaute, O | 1 |
| Cendrowska-Pinkosz, M; Krauze, M; Truchliński, J | 1 |
| Ashizawa, N; Inoue, T; Iwanaga, T; Matsumoto, K; Nagata, O; Nakamura, H; Sato, T | 1 |
| Antunes, C; Böhmer, AE; Elisabetsky, E; Lara, DR; Porciúncula, LO; Schallenberger, C; Schmidt, AP; Souza, DO | 1 |
| John, SA; Revin, SB | 2 |
| Baumgartner, S; Fleischmann, R; Hingorani, V; Kerr, B; Manhard, K; Miner, JN; Polvent, E; Quart, B; Shen, Z; Suster, M; Yeh, LT | 1 |
| Hingorani, V; Kerr, B; Manhard, K; Quart, B; Rowlings, C; Shen, Z; Storgard, C; Yeh, LT | 1 |
| Kumagai, H; Matsubara, H; Nishida, Y; Onimaru, H; Oshima, N; Takechi, H; Uchida, T; Watanabe, A | 1 |
| Gillen, M; Kerr, B; Shen, Z; Wallach, K; Yeh, LT; Zhu, N | 1 |
| Girardet, JL; Hagerty, DT; Hyndman, D; Iverson, C; Liu, S; Manhard, K; Miner, JN; Nanavati, P; Quart, B; Shen, Z; Tan, PK; Terkeltaub, R; Yeh, LT | 1 |
| Adler, S; Bardin, T; Baumgartner, S; Bhakta, N; Fung, M; Keenan, RT; Khanna, PP; Kopicko, J; So, A; Storgard, C | 1 |
| Gillen, M; Harmon, E; Kerr, B; Lee, CA; Nguyen, M; Shen, Z; Tieu, K; Wilson, DM | 1 |
| Gillen, M; Kerr, B; Lee, CA; Shen, Z; Valdez, S; Zhou, D | 1 |
| Deeks, ED | 1 |
| Adler, S; Baumgartner, S; Bhakta, N; Dalbeth, N; Fung, M; Jones, G; Khanna, D; Kopicko, J; Perez-Ruiz, F; Storgard, C; Terkeltaub, R | 1 |
| Bábíčková, J; Borbélyová, V; Celec, P; Domonkos, E; Hodosy, J; Kačmárová, M; Ostatníková, D; Tóthová, Ľ; Uličná, O | 1 |
| Bai, X; He, J; Li, T; Qiao, H; Xu, J; Ye, X; Zhang, J; Zhang, W | 1 |
| Hill-McManus, D; Hughes, D; Lane, S; Marshall, S; Soto, E | 2 |
| Day, R; Jones, G; Panova, E | 1 |
| Abhishek, A | 1 |
| Cai, W; Liu, W; Liu, Y; Tang, L; Wang, J; Wu, J; Xie, Y; Xu, W; Zhang, S; Zhao, G | 1 |
| Aksenov, S; Eriksson, UG; Peck, CC; Stanski, DR | 1 |
| Kuehn, BM | 1 |
| Baumgartner, S; Kerr, B; Manhard, K; Quart, B; Shen, Z; Yeh, LT | 1 |
| Chen, R; Du, Z; Jia, Z; Liu, J; Sun, J; Wang, K; Xin, Y; Xu, Q; Xu, T; Zhang, C | 1 |
| Gillen, M; Hall, J; Ito, Y; Liu, S; Shen, Z; Shiramoto, M; Yamamoto, A; Yan, X | 1 |
| Gillen, M; Hall, J; Kerr, BM; Lee, CA; Shah, V; Shen, Z; Tieu, K; Wilson, DM; Yang, C | 1 |
| Baumgartner, S; Goldfarb, DS; Jalal, D; Pillinger, M; Saag, KG; Schechter, BM; Terkeltaub, R; Valiyil, R; White, WB | 1 |
| Robinson, PC | 1 |
| Girardet, JL; Lee, CA; Miner, JN; Renner, M; Shen, Z; Wilson, DM; Yang, C; Zhou, D | 1 |
| Fields, TR | 1 |
| Bartsch, LA; Castillo-Rodriguez, E; Fernandez-Prado, R; Kanbay, M; Ortiz, A; Perez-Gomez, MV | 1 |
| Gupta, MK; Singh, JA | 1 |
| Lee, YH; Song, GG | 1 |
| Alghamdi, YS; Nassan, MA; Soliman, MM | 1 |
| Chen, TT; Cheng, FM; Lin, CC; Tien, JZ; Yeh, SP | 1 |
| Guo, S; Hu, SS; Lu, PF; Meng, FH; Wang, ZR; Zhang, TJ; Zhang, X; Zhang, Y; Zhang, ZH | 1 |
8 review(s) available for uric acid and triazoles
| Article | Year |
|---|---|
Lesinurad: A Review in Hyperuricaemia of Gout.
Topics: Adult; Allopurinol; Drug Therapy, Combination; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Kidney; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase | 2017 |
Guideline development for the management of gout: role of combination therapy with a focus on lesinurad.
Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Patient Selection; Practice Guidelines as Topic; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents | 2017 |
New urate-lowing therapies.
Topics: Acetamides; Drug Interactions; Enzyme Inhibitors; Gout; Gout Suppressants; Humans; Phenylacetates; Probenecid; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents | 2018 |
Gout - An update of aetiology, genetics, co-morbidities and management.
Topics: Allopurinol; Chronic Disease; Comorbidity; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thioglycolates; Triazoles; Uric Acid | 2018 |
The Challenges of Approaching and Managing Gout.
Topics: Acetamides; Allopurinol; Antibodies, Monoclonal, Humanized; Colchicine; Diet Therapy; Febuxostat; Gout; Gout Suppressants; Humans; Medication Adherence; Patient Education as Topic; Phenylacetates; Polyethylene Glycols; Quality of Health Care; Rheumatology; Thioglycolates; Triazoles; Urate Oxidase; Uric Acid | 2019 |
Potential Dangers of Serum Urate-Lowering Therapy.
Topics: Cardiovascular Diseases; Gout Suppressants; Humans; Oxidative Stress; Polyethylene Glycols; Thioglycolates; Triazoles; Urate Oxidase; Uric Acid; Xanthine Oxidase | 2019 |
Cardiovascular Disease in Gout and the Protective Effect of Treatments Including Urate-Lowering Therapy.
Topics: Allopurinol; Anti-Inflammatory Agents; Cardiovascular Diseases; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid | 2019 |
Comparative efficacy and safety of lesinurad 200 mg and 400 mg combined with a xanthine oxidase inhibitor in hyperuricemic patients with gout: A Bayesian network meta-analysis of randomized controlled trials
.
Topics: Bayes Theorem; Drug Therapy, Combination; Gout; Humans; Network Meta-Analysis; Randomized Controlled Trials as Topic; Thioglycolates; Triazoles; Uric Acid; Xanthine Oxidase | 2019 |
11 trial(s) available for uric acid and triazoles
| Article | Year |
|---|---|
Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Blood Chemical Analysis; Blood Glucose; Blood Proteins; Dose-Response Relationship, Drug; Female; Triazoles; Triglycerides; Turkeys; Uric Acid | 2007 |
Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
Topics: Adult; Aged; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Thioglycolates; Triazoles; Uric Acid | 2014 |
Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Capsules; Cross-Over Studies; Double-Blind Method; Gastrointestinal Absorption; Healthy Volunteers; Humans; Male; Organic Anion Transporters; Organic Cation Transport Proteins; Pharmaceutical Solutions; Renal Elimination; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents; Young Adult | 2015 |
Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney.
Topics: Cell Line; Gout; Humans; Kidney; Male; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents | 2016 |
Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Cardiovascular Diseases; Creatinine; Double-Blind Method; Drug Therapy, Combination; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Renal Insufficiency; Retreatment; Symptom Flare Up; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents; Young Adult | 2017 |
Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Biological Availability; Biomarkers; Creatinine; Female; Glomerular Filtration Rate; Gout Suppressants; Humans; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; Renal Elimination; Severity of Illness Index; Thioglycolates; Triazoles; Uric Acid | 2016 |
Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial.
Topics: Creatinine; Double-Blind Method; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid | 2017 |
The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout.
Topics: Adult; Allopurinol; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Thioglycolates; Triazoles; Uric Acid | 2018 |
Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study.
Topics: Administration, Oral; Adult; Aged; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Time Factors; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Young Adult | 2018 |
Metabolism and disposition of lesinurad, a uric acid reabsorption inhibitor, in humans.
Topics: Adult; Biological Availability; Cytochrome P-450 CYP2C9; Humans; Infusions, Intravenous; Male; Renal Elimination; Thioglycolates; Triazoles; Uric Acid | 2019 |
Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers.
Topics: Administration, Oral; Adult; Gout; Healthy Volunteers; HEK293 Cells; Humans; Kidney; Male; Microsomes, Liver; Middle Aged; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Renal Reabsorption; Stereoisomerism; Structure-Activity Relationship; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents; Young Adult | 2019 |
23 other study(ies) available for uric acid and triazoles
| Article | Year |
|---|---|
Properties of glutathione release observed during reduction of organic hydroperoxide, demethylation of aminopyrine and oxidation of some substances in perfused rat liver, and their implications for the physiological function of catalase.
Topics: Aminopyrine; Animals; Benzylamines; Catalase; Cell Separation; Glutathione; Glutathione Peroxidase; Glycolates; Liver; Male; Mitochondria, Liver; NADP; Nucleotides; Oxidation-Reduction; Perfusion; Peroxides; Phenobarbital; Rats; Triazoles; Uric Acid | 1977 |
3,5-disubstituted 1,2,3,4-triazoles, 1 new class of xanthine oxidase inhibitor.
Topics: Aerobiosis; Allantoin; Anaerobiosis; Animals; Dogs; Enterohepatic Circulation; Ferritins; Haplorhini; Hylobates; Hypoxanthines; Kinetics; Oxidation-Reduction; Polynucleotides; Rats; Saimiri; Species Specificity; Triazoles; Uric Acid; Xanthine Oxidase | 1975 |
Action of 8-azaguanine and 8-azaxanthine on Pseudomonas aeruginosa.
Topics: Antimetabolites; Azaguanine; In Vitro Techniques; Pseudomonas aeruginosa; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines | 1964 |
Anti-inflammatory effect of a PAF receptor antagonist and a new molecule with antiproteinase activity in an experimental model of acute urate crystal arthritis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Azepines; C-Reactive Protein; Dinoprostone; Disease Models, Animal; Indenes; Interleukin-6; Joints; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protease Inhibitors; Rabbits; Random Allocation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synovial Fluid; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha; Uric Acid | 1996 |
Design, synthesis, and pharmacological and pharmacokinetic evaluation of 3-phenyl-5-pyridyl-1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors.
Topics: Animals; Cattle; Cytochrome P-450 CYP3A Inhibitors; Drug Design; Drug Interactions; Enzyme Inhibitors; Nitriles; Pharmacokinetics; Rats; Structure-Activity Relationship; Triazoles; Uric Acid; Xanthine Dehydrogenase | 2009 |
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Allopurinol; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamic Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrimidines; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines | 2009 |
Selective determination of inosine in the presence of uric acid and hypoxanthine using modified electrode.
Topics: Biosensing Techniques; Electrochemical Techniques; Electrodes; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Inosine; Microscopy, Atomic Force; Oxidation-Reduction; Triazoles; Uric Acid | 2012 |
Highly sensitive determination of uric acid in the presence of major interferents using a conducting polymer film modified electrode.
Topics: Ascorbic Acid; Carbon; Dopamine; Electric Conductivity; Electrodes; Humans; Methionine; Microscopy, Atomic Force; Polymers; Reproducibility of Results; Triazoles; Tyrosine; Uric Acid | 2012 |
Uric acid, indoxyl sulfate, and methylguanidine activate bulbospinal neurons in the RVLM via their specific transporters and by producing oxidative stress.
Topics: Animals; Anion Transport Proteins; Benzoxazoles; Enzyme Inhibitors; Indican; Medulla Oblongata; Membrane Glycoproteins; Membrane Potentials; Methylguanidine; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neurons; Neuroprotective Agents; Neurotoxins; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Patch-Clamp Techniques; Rats, Wistar; Renal Insufficiency, Chronic; Sympathetic Nervous System; Triazoles; Uric Acid | 2015 |
In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters.
Topics: Adolescent; Adult; Aged; Atorvastatin; Carrier Proteins; Cell Line; Diuretics; Drug Interactions; Furosemide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Kidney; Liver; Liver-Specific Organic Anion Transporter 1; Male; Metformin; Middle Aged; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents; Young Adult | 2016 |
Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study.
Topics: Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Europe; Female; Heart Rate; Humans; Male; Statistics as Topic; Thioglycolates; Triazoles; Uric Acid; Xanthine Oxidase | 2016 |
Does long-term androgen deficiency lead to metabolic syndrome in middle-aged rats?
Topics: Age Factors; Andropause; Animals; Aromatase Inhibitors; Biomarkers; Blood Glucose; Blood Pressure; Cholesterol; Disease Models, Animal; Estradiol; Female; Hormone Replacement Therapy; Hypogonadism; Letrozole; Liver; Liver Diseases; Male; Metabolic Syndrome; Nitriles; Orchiectomy; Ovariectomy; Rats, Inbred Lew; Sex Factors; Sexual Development; Testosterone; Triazoles; Uric Acid | 2017 |
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobarbital; Pyrimidines; Rats; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazoles; Uric Acid; Xanthines | 2017 |
Impact of non-adherence on the safety and efficacy of uric acid-lowering therapies in the treatment of gout.
Topics: Computer Simulation; Drug Therapy, Combination; Febuxostat; Gout; Gout Suppressants; Humans; Male; Medication Adherence; Models, Biological; Risk Assessment; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid; Xanthine Oxidase | 2018 |
Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor.
Topics: Benzbromarone; Biological Transport, Active; Carbon Radioisotopes; Drug Design; Gene Expression; HEK293 Cells; Humans; Methane; Organic Anion Transporters; Organic Cation Transport Proteins; Structure-Activity Relationship; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents | 2018 |
Individualized treatment strategies for hyperuricemia informed by a semi-mechanistic exposure-response model of uric acid dynamics.
Topics: Allopurinol; Clinical Trials as Topic; Febuxostat; Humans; Hyperuricemia; Models, Theoretical; Precision Medicine; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents | 2018 |
Chronic Disease Approaches Needed to Curb Gout's Growing Burden.
Topics: Allopurinol; Chronic Disease; Diet; Drug Combinations; Febuxostat; Gout; Gout Suppressants; Healthy Lifestyle; Humans; Patient Education as Topic; Practice Guidelines as Topic; Purines; Thioglycolates; Triazoles; Uric Acid | 2018 |
Zurampic Protects Pancreatic β-Cells from High Uric Acid Induced-Damage by Inhibiting URAT1 and Inactivating the ROS/AMPK/ERK Pathways.
Topics: AMP-Activated Protein Kinases; Animals; Anion Transport Proteins; Extracellular Signal-Regulated MAP Kinases; Insulin-Secreting Cells; MAP Kinase Signaling System; Rats; Reactive Oxygen Species; Thioglycolates; Triazoles; Uric Acid | 2018 |
Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gout; Gout Suppressants; Humans; Kidney Diseases; Male; Middle Aged; Randomized Controlled Trials as Topic; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid; Xanthine Oxidase; Young Adult | 2019 |
Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model.
Topics: Allopurinol; Cohort Studies; Cost-Benefit Analysis; Drug Therapy, Combination; Economics, Pharmaceutical; Febuxostat; Gout; Gout Suppressants; Health Care Costs; Humans; Medication Adherence; Models, Biological; Models, Economic; Quality of Life; Quality-Adjusted Life Years; Thioglycolates; Treatment Outcome; Triazoles; United Kingdom; Uric Acid | 2018 |
Impact of Lesinurad and allopurinol on experimental Hyperuricemia in mice: biochemical, molecular and Immunohistochemical study.
Topics: Allopurinol; Animals; Blood Urea Nitrogen; Catalase; Drug Synergism; Glutathione Peroxidase; Gout Suppressants; Hyperuricemia; Interleukin-1beta; Kidney; Liver; Male; Mice; Thioglycolates; Triazoles; Tumor Necrosis Factor-alpha; Uric Acid; Xanthine Oxidase | 2020 |
Venetoclax plus cytochrome P450 inhibitors without ramp-up strategy led to low risk of tumor lysis syndrome in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Child; Creatinine; Cytochrome P-450 Enzyme Inhibitors; Drug Administration Schedule; Drug Synergism; Female; Humans; Hyperuricemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Sulfonamides; Triazoles; Tumor Lysis Syndrome; Urate Oxidase; Uric Acid; Young Adult | 2020 |
Discovery of 4-(phenoxymethyl)-1H-1,2,3-triazole derivatives as novel xanthine oxidase inhibitors.
Topics: Animals; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Hyperuricemia; Ligands; Models, Molecular; Molecular Structure; Oxonic Acid; Rats; Structure-Activity Relationship; Triazoles; Uric Acid; Xanthine Oxidase | 2022 |