uric acid and theobromine

uric acid has been researched along with theobromine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199014 (37.84)18.7374
1990's6 (16.22)18.2507
2000's6 (16.22)29.6817
2010's7 (18.92)24.3611
2020's4 (10.81)2.80

Authors

AuthorsStudies
Cameron, IL; Lyles, MB; Rawls, HR1
Bearne, SL; Lunn, FA; Roy, AC1
Shoyab, M1
Desiraju, RK; Mayock, RL; Sugita, ET1
Kihlman, BA; Sturelid, S1
Birkett, DJ; Lelo, A; Miners, JO1
Hafkenscheid, JC; Hekster, YA; Nouws, JF; Vree, JB; Vree, TB1
Brunk, SF; Ferguson, RK; Leaverton, PE; Nordschow, CD; Toubes, DB; Wilson, WR1
Cornish, HH; Khanna, KL; Rao, GS2
Riegelman, S; Shah, VP1
Allam, AM; Elzainy, TA1
Gehl, A; Rink, M1
Kela, U; Trivedi, CP; Vijayvargiya, R1
Bonati, M; Garattini, S; Latini, R; Marzi, E1
Andersson, T; Birkett, DJ; McManus, ME; Miners, JO; Tassaneeyakul, W; Tukey, RH; Veronese, ME1
Benchekroun, Y; Brazier, JL; Dautraix, S; Désage, M1
Lunte, CE; Zhao, Y1
Gates, S; Miners, JO1
Madhavi, YS; Madyastha, KM; Sridhar, GR; Vadiraja, BB1
Azam, S; Hadi, N; Hadi, SM; Khan, NU1
JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ1
SIMON, MI; VANVUNAKIS, H1
Baranowska, I; Baranowski, J; Zydroń, M1
Miyazaki, K; Mochizuki, T; Sugawara, M; Takekuma, Y1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Yu, CL1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL1
Gong, P; He, RR; Hu, HH; Kurihara, H; Li, SB; Li, YF; Mao, ZF; Ouyang, SH; Tsoi, B; Wu, YP1
Costa-Bauza, A; Grases, F; Rodriguez, A1
Camandola, S; Cutler, RG; Edelhauser, MA; Malott, KF; Mattson, MP1
Dong, ZB; Liang, YR; Lu, J; Ma, YX; Wu, HS; Wu, XH; Ye, JH; Zheng, XQ1
Calvó, P; Costa-Bauza, A; Grases, F; Prieto, RM; Rodriguez, A1
Chattaraj, KG; Paul, S1
Benejam, J; Calvó, P; Costa-Bauza, A; Grases, F; Hernandez, Y; Sanchis, P1
Kertys, M; Kmeťová, K; Maráková, K; Mokrý, J; Pršo, K; Žideková, N1
Berga, F; Costa-Bauza, A; Grases, F; Julià, F1
Calvó, P; Costa-Bauzá, A; Grases, F; Hernández, Y1

Reviews

1 review(s) available for uric acid and theobromine

ArticleYear
The Role of Uric Acid and Methyl Derivatives in the Prevention of Age-Related Neurodegenerative Disorders.
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:21

    Topics: Aging; Animals; Caffeine; Dietary Supplements; Humans; Mammals; Neurodegenerative Diseases; Theobromine; Theophylline; Uric Acid

2015

Trials

2 trial(s) available for uric acid and theobromine

ArticleYear
A teaching format in clinical pharmacology. Comparison of two xanthines and a placebo.
    The Journal of clinical pharmacology and new drugs, 1973, Volume: 13, Issue:4

    Topics: Adult; Blood Glucose; Blood Pressure; Caffeine; Education, Medical, Undergraduate; Humans; Pharmacology; Placebos; Pulse; Respiration; Stimulation, Chemical; Teaching; Theobromine; Uric Acid; Xanthines

1973
Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine.
    Nutrients, 2020, Jul-07, Volume: 12, Issue:7

    Topics: Aged; Citric Acid; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Male; Middle Aged; Nephrolithiasis; Recurrence; Theobromine; Treatment Outcome; Uric Acid

2020

Other Studies

34 other study(ies) available for uric acid and theobromine

ArticleYear
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
    Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

    Topics: Acridine Orange; Intercalating Agents; Methylation; Nonlinear Dynamics; Spectrophotometry; Structure-Activity Relationship; Xanthines

2001
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines

2010
The stimulation of murine hepatic aryl hydrocarbon hydroxylase activity in vitro by caffeine.
    Cancer letters, 1979, Volume: 8, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Binding Sites; Caffeine; DNA; Hypoxanthines; In Vitro Techniques; Mice; Microsomes, Liver; Stimulation, Chemical; Theobromine; Theophylline; Uric Acid

1979
Determination of theophylline and its metabolites by liquid chromatography.
    Journal of chromatographic science, 1977, Volume: 15, Issue:12

    Topics: Chromatography, High Pressure Liquid; Humans; Saliva; Theobromine; Theophylline; Uric Acid; Xanthines

1977
Enhancement by methylated oxypurines of the frequency of induced chromosomal aberrations.
    Hereditas, 1975, Volume: 79, Issue:1

    Topics: Animals; Caffeine; Cell Line; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cricetinae; Drug Synergism; Methylation; Mutation; Plants; Purines; Theobromine; Theophylline; Thiotepa; Uric Acid

1975
Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:8

    Topics: Acetylcysteine; Animals; Cimetidine; Cysteine; Cytochrome P-450 Enzyme System; Dithiothreitol; Glutathione; Kinetics; Male; Metyrapone; Microsomes, Liver; Pyridines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theobromine; Uracil; Uric Acid

1990
Excretion and metabolism of a series of xanthines by the turtle Pseudemys scripta elegans.
    The veterinary quarterly, 1989, Volume: 11, Issue:1

    Topics: Animals; Caffeine; Theobromine; Theophylline; Turtles; Uric Acid; Xanthine; Xanthines

1989
Metabolism of caffeine- 3 H in the rat.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:4

    Topics: Animals; Caffeine; Chromatography, Thin Layer; Male; Mass Spectrometry; Rats; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Tritium; Uric Acid; Xanthines

1972
Mass spectrometric identification of methylxanthines and methyluric acids, the possible metabolites of caffeine.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:11

    Topics: Caffeine; Chromatography, Gas; Mass Spectrometry; Methods; Methylation; Theobromine; Theophylline; Uric Acid; Xanthines

1972
GLC determination of theophylline in biological fluids.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:8

    Topics: Barbiturates; Chromatography, Gas; Indicators and Reagents; Methods; Quaternary Ammonium Compounds; Saliva; Solvents; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Uric Acid; Xanthines

1974
Purine catabolism in Fusarium moniliforme.
    Journal of general microbiology, 1970, Volume: 63, Issue:2

    Topics: Allantoin; Amidohydrolases; Ammonia; Caffeine; Cell-Free System; Culture Media; Fusarium; Glyoxylates; Hydantoins; Hypoxanthines; Purines; Theobromine; Time Factors; Urate Oxidase; Urea; Urease; Ureohydrolases; Uric Acid; Xanthenes

1970
[Thin-layer chromatographic separation of some purine derivatives, including uric acid].
    Journal of chromatography, 1966, Volume: 21, Issue:1

    Topics: Adenine; Caffeine; Chromatography, Thin Layer; Guanine; Hypoxanthines; Purines; Theobromine; Theophylline; Uric Acid; Xanthines

1966
Inhibitory effects of methylxanthines on the activity of xanthine oxidase.
    Life sciences, 1980, Dec-01, Volume: 27, Issue:22

    Topics: Animals; Brain; Buffaloes; Caffeine; Female; In Vitro Techniques; Kidney; Kinetics; Lung; Milk; Myocardium; Rats; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase; Xanthines

1980
Urinary excretion of an uracilic metabolite from caffeine by rat, monkey and man.
    Toxicology letters, 1981, Volume: 7, Issue:3

    Topics: Adult; Animals; Biotransformation; Caffeine; Humans; Macaca fascicularis; Male; Rats; Species Specificity; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines

1981
Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms.
    Biochemical pharmacology, 1994, May-18, Volume: 47, Issue:10

    Topics: Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Oxidoreductases; Theobromine; Theophylline; Uric Acid

1994
Isotopic effects on retention times of caffeine and its metabolites 1,3,7-trimethyluric acid, theophylline, theobromine and paraxanthine.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jan-24, Volume: 688, Issue:2

    Topics: Animals; Caffeine; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Kidney; Male; Rats; Rats, Wistar; Theobromine; Theophylline; Uric Acid

1997
Determination of caffeine and its metabolites by micellar electrokinetic capillary electrophoresis.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jan-24, Volume: 688, Issue:2

    Topics: Animals; Beverages; Buffers; Caffeine; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Rats; Sodium Dodecyl Sulfate; Tablets; Theobromine; Theophylline; Uric Acid

1997
Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism.
    British journal of clinical pharmacology, 1999, Volume: 47, Issue:3

    Topics: Animals; COS Cells; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2E1; DNA, Complementary; Enzyme Inhibitors; Gene Expression; Humans; Kinetics; Microsomes, Liver; Recombinant Fusion Proteins; Substrate Specificity; Theobromine; Uric Acid; Xanthines

1999
Purification and partial characterization of caffeine oxidase--A novel enzyme from a mixed culture consortium.
    Biochemical and biophysical research communications, 1999, Sep-24, Volume: 263, Issue:2

    Topics: Caffeine; Klebsiella; Oxidation-Reduction; Oxygenases; Rhodococcus; Substrate Specificity; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase

1999
Antioxidant and prooxidant properties of caffeine, theobromine and xanthine.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:9

    Topics: Animals; Antioxidants; Caffeine; Cattle; Copper; DNA; DNA Damage; Hydroxyl Radical; Oxidants; Plasmids; Theobromine; Uric Acid; Xanthine

2003
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines

1963
THE DYE-SENSITIZED PHOTOOXIDATION OF PURINE AND PYRIMIDINE DERIVATIVES.
    Archives of biochemistry and biophysics, 1964, Volume: 105

    Topics: Caffeine; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Infrared Rays; Light; Manometry; Methylene Blue; Nucleosides; Oxidation-Reduction; Purines; Research; Theobromine; Theophylline; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uric Acid; Xanthines

1964
Separation, pre-concentration, and HPLC analysis of methylxanthines in urine samples.
    Journal of separation science, 2004, Volume: 27, Issue:14

    Topics: Caffeine; Calibration; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Theobromine; Uric Acid; Urine; Xanthines

2004
Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites.
    Biochimica et biophysica acta, 2005, Aug-15, Volume: 1714, Issue:2

    Topics: Animals; Biological Transport; Caffeine; CHO Cells; Cricetinae; Cricetulus; Humans; Molecular Structure; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Theobromine; Theophylline; Uric Acid; Xanthines

2005
A novel caffeine dehydrogenase in Pseudomonas sp. strain CBB1 oxidizes caffeine to trimethyluric acid.
    Journal of bacteriology, 2008, Volume: 190, Issue:2

    Topics: Bacterial Proteins; Caffeine; Oxidoreductases; Pseudomonas; Substrate Specificity; Theobromine; Ubiquinone; Uric Acid; Xanthine

2008
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
    Journal of bacteriology, 2009, Volume: 191, Issue:14

    Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2009
Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats.
    Journal of the science of food and agriculture, 2015, Volume: 95, Issue:6

    Topics: Animals; Blood Pressure; Caffeine; Camellia sinensis; Epinephrine; Hypertension; Male; Norepinephrine; Plant Extracts; Rats, Inbred SHR; Rats, Wistar; Species Specificity; Tea; Theobromine; Uric Acid; Xanthines

2015
Theobromine inhibits uric acid crystallization. A potential application in the treatment of uric acid nephrolithiasis.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Caffeine; Crystallization; Humans; Microscopy, Electron, Scanning; Nephrolithiasis; Oxalates; Theobromine; Uric Acid

2014
Different Catabolism Pathways Triggered by Various Methylxanthines in Caffeine-Tolerant Bacterium
    Journal of microbiology and biotechnology, 2018, Jul-28, Volume: 28, Issue:7

    Topics: Biodegradation, Environmental; Caffeine; Drug Tolerance; Gardens; Metabolic Networks and Pathways; Pseudomonas putida; Soil; Soil Microbiology; Substrate Specificity; Tea; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2018
Effect of Consumption of Cocoa-Derived Products on Uric Acid Crystallization in Urine of Healthy Volunteers.
    Nutrients, 2018, Oct-16, Volume: 10, Issue:10

    Topics: Adult; Aged; Caffeine; Chocolate; Coffee; Creatinine; Crystallization; Diet; Eating; Female; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Oxalates; Theobromine; Uric Acid; Young Adult

2018
Inclusion of Theobromine Modifies Uric Acid Aggregation with Possible Changes in Melamine-Uric Acid Clusters Responsible for Kidney Stones.
    The journal of physical chemistry. B, 2019, 12-12, Volume: 123, Issue:49

    Topics: Kidney Calculi; Molecular Dynamics Simulation; Theobromine; Triazines; Uric Acid

2019
Simultaneous determination of caffeine and its metabolites in rat plasma by UHPLC-MS/MS.
    Journal of separation science, 2021, Volume: 44, Issue:23

    Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry; Theobromine; Theophylline; Uric Acid

2021
Effect of theobromine on dissolution of uric acid kidney stones.
    World journal of urology, 2022, Volume: 40, Issue:8

    Topics: Acetylcysteine; Humans; Kidney Calculi; Solubility; Theobromine; Uric Acid

2022
Efficacy of Theobromine and Its Metabolites in Reducing the Risk of Uric Acid Lithiasis.
    International journal of molecular sciences, 2023, Jun-29, Volume: 24, Issue:13

    Topics: Humans; Lithiasis; Nephrolithiasis; Pharmaceutical Preparations; Theobromine; Uric Acid

2023