uric acid has been researched along with pyrazines in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (83.33) | 18.7374 |
| 1990's | 1 (2.08) | 18.2507 |
| 2000's | 1 (2.08) | 29.6817 |
| 2010's | 1 (2.08) | 24.3611 |
| 2020's | 5 (10.42) | 2.80 |
| Authors | Studies |
|---|---|
| Weinman, EJ | 1 |
| Cadenhead, A; Cameron, JS; Hatfield, PJ; Simmonds, HA | 1 |
| Bohn, DL; Fanelli, GM; Zacchei, AG | 1 |
| Mikkelsen, E; Pedersen, OL | 1 |
| Simpson, FO; Waal-Manning, HJ | 1 |
| Benvenuti, C; Sanguigni, D | 1 |
| Fanelli, GM; Weiner, IM | 3 |
| Roch-Ramel, F; Weiner, IM | 1 |
| Prasad, DR; Steele, TH; Weiner, IM | 1 |
| Gougoux, A; Kiss, A; Lemieux, G; Vinay, P | 1 |
| Ellard, GA; Haslam, RM | 1 |
| Dirks, JH; Roch-Ramel, F; Wong, NL | 1 |
| Bühring, KU; Leopold, G; Pabst, J; Simane, Z; Ungethüm, W | 1 |
| Degaute, JP; Demanet, JC; Fichefet, JP; Hubert, C; Paduart, P | 1 |
| Kennedy, RD; MacFarlane, JP | 1 |
| Tinker, JP; Weiner, IM | 1 |
| Wawrzeńczyk, B; Zaruski, A | 1 |
| Falase, AO; Salako, LA | 1 |
| Bohn, D; Fanelli, GM; Stafford, S | 1 |
| Croxson, MS; John, MB; Neutze, JM | 1 |
| Antcliff, AC; Beevers, DG; Hamilton, M; Harpur, JE | 1 |
| Foulkes, EC; Nolan, RP | 1 |
| Kropp, R | 1 |
| Bohn, DL; Fanelli, GM; Reilly, SS | 1 |
| Lant, AF; Wilson, GM | 1 |
| Berndt, WO; McAlary, B; Mudge, GH | 1 |
| Berndt, WO; Cucchi, J; Mudge, GH; O'Connell, JM; Platts, M | 1 |
| Mariani, B | 1 |
| Freis, ED; Gombos, EA; Moghadam, A | 1 |
| Berlind, S; Lundvall, O | 1 |
| Bolzano, K; Krempler, F; Sandhofer, F | 1 |
| Ferrara, LA; Galletti, F; Siani, A; Strazzullo, P | 1 |
| Pittaway, D | 1 |
| Gillies, A; Morgan, TO; Myers, JB; Waga, S | 1 |
| Aroldi, A; Colussi, G; D'Angelo, A; Fabris, A; Graziani, G; Mandressi, A; Maschio, G; Minetti, L; Pagano, F; Ponticelli, C; Rocco, F; Surian, M; Tasca, A; Tessitore, N; Trinchieri, A | 1 |
| Ambrosioni, E; Bassein, L; Lusa, AM; Magnani, B; Tartagni, F | 1 |
| Alcazar, JM; Diaz, VP; Jarillo, MD; Millet, VG; Rodicio, JL; Ruilope, L | 1 |
| Balogh, Z; Boda, J; Kárpáti, L; Kovács, P; Leövey, A; Paragh, G; Szabó, J | 1 |
| BEECHWOOD, EC; BERNDT, WO; MUDGE, GH | 1 |
| Behera, S; Raj, CR | 1 |
| Afify, HG; Attia, MS; El-Kemary, M; Elsaady, MM; Hashem, SG; Omer, WE; Youssef, AO | 1 |
| Abe, T; Anzai, N; Mishima, E; Miyazaki, M | 1 |
| Hase, R; Ishida, K; Kurata, R; Kurita, T; Mito, H; Muranaka, E | 1 |
| Chiaki, T; Kinjo, T; Kondo, D; Kubota, K; Minami, S; Moriiwa, Y; Morikawa, G; Okazawa, K; Takanashi, Y; Yanagida, A | 1 |
| Doi, Y; Iwasaki, H; Koseki, T; Mizuno, T; Nakajima, K; Takahashi, K; Yamada, S | 1 |
| Hanai, Y; Ishii, Y; Mabuchi, T; Matsuo, K; Miyazaki, T; Nishimura, K; Nishizawa, K; Ohashi, H; Tateda, K; Uekusa, S; Yoshio, T; Yoshizawa, S | 1 |
1 review(s) available for uric acid and pyrazines
| Article | Year |
|---|---|
Uric Acid Elevation by Favipiravir, an Antiviral Drug.
Topics: Aldehyde Oxidase; Amides; Antiviral Agents; Biotransformation; Coronavirus Infections; COVID-19; Drug Interactions; Humans; Hyperuricemia; Kidney; Kidney Diseases; Molecular Structure; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Pandemics; Pneumonia, Viral; Pyrazines; Uric Acid; Xanthine Oxidase | 2020 |
11 trial(s) available for uric acid and pyrazines
| Article | Year |
|---|---|
Beta-blockers and uric-acid excretion.
Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol; Uric Acid | 1978 |
One year follow-up of hyperuricaemic hypertensive patients treated with tienilic acid or a diuretic with or without uric acid-lowering drugs.
Topics: Alkaline Phosphatase; Amiloride; Aspartate Aminotransferases; Bilirubin; Blood Pressure; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Female; Follow-Up Studies; Glycolates; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Pyrazines; Sodium Chloride Symporter Inhibitors; Ticrynafen; Uric Acid | 1979 |
[Esmaloride--a new potassium neutral diuretic combination. Clinical pharmacologic properties].
Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Body Weight; Creatinine; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Male; Potassium; Pyrazines; Trichlormethiazide; Triglycerides; Uric Acid; Water-Electrolyte Balance | 1985 |
The effects of amiloride during diuretic therapy in elderly subjects.
Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinations; Edema; Female; Humans; Hydrochlorothiazide; Hypokalemia; Male; Potassium; Pyrazines; Sodium; Urea; Uric Acid | 1972 |
Amiloride hydrochloride combined with hydrochlorothiazide in the control of hypertension and plasma potassium levels.
Topics: Alanine Transaminase; Amiloride; Aspartate Aminotransferases; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Pyrazines; Urea; Uric Acid | 1972 |
Long-term therapy of diabetes insipidus with oral benzothiadiazine and phthalimidine diuretics.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Benzothiadiazines; Blood Glucose; Child; Diabetes Insipidus; Diuretics; Drug Synergism; Female; Humans; Hydroflumethiazide; Hypokalemia; Indoles; Male; Middle Aged; Polythiazide; Potassium; Pyrazines; Sodium; Time Factors; Triamterene; Uric Acid; Water-Electrolyte Balance | 1971 |
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension].
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Posture; Pulse; Pyrazines; Urea; Uric Acid | 1984 |
Long term treatment with tienilic acid or thiazides: comparison of antihypertensive and metabolic effects.
Topics: Adult; Amiloride; Blood Pressure; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Liver Function Tests; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Ticrynafen; Uric Acid | 1983 |
Evaluation of a fixed combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A long-term multicentre trial.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diastole; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Potassium; Propanolamines; Pulse; Pyrazines; Systole; Time Factors; Timolol; Uric Acid | 1980 |
Effect of tienilic acid and amiloride in healthy volunteers and in hypertensives with normal renal function.
Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Electrolytes; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged; Pyrazines; Ticrynafen; Uric Acid | 1980 |
Effects of tienilic acid used alone and in association with triamterene or amiloride on urinary excretion of electrolytes.
Topics: Amiloride; Diuresis; Drug Interactions; Electrolytes; Female; Glycolates; Humans; Male; Middle Aged; Pyrazines; Ticrynafen; Triamterene; Uric Acid | 1981 |
36 other study(ies) available for uric acid and pyrazines
| Article | Year |
|---|---|
Uric acid and the kidney.
Topics: Acute Kidney Injury; Ammonia; Animals; Glomerular Filtration Rate; Glutamine; Gout; Humans; Hydrogen-Ion Concentration; Kidney; Kidney Calculi; Kidney Diseases; Kidney Failure, Chronic; Kidney Tubules; Metabolic Diseases; Pyrazines; Uric Acid | 1976 |
Uric acid excretion by the pig kidney.
Topics: Animals; Blood Proteins; Diuresis; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Kidney; Male; Probenecid; Pyrazinamide; Pyrazines; Swine; Uric Acid; Urine | 1976 |
Renal excretion of a slauretic-uricosuric agent (MK-196) and interaction with a urate-retaining drug, pyrazinoate, in the chimpanzee.
Topics: Acetazolamide; Animals; Diuresis; Drug Interactions; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Indans; Indenes; Kidney; Male; p-Aminohippuric Acid; Pan troglodytes; Probenecid; Pyrazinamide; Pyrazines; Sodium Chloride; Time Factors; Uric Acid; Uricosuric Agents | 1977 |
[Comparison of spironolactone and amiloride combined with hydrochlorothiazide in the treatment of slight or moderate hypertension].
Topics: Amiloride; Blood Glucose; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Spironolactone; Uric Acid | 1978 |
Renal urate excretion in animal models.
Topics: Allopurinol; Animals; Carboxylic Acids; Dogs; Goats; Haplorhini; Humans; Kidney; Kidney Tubules, Proximal; Male; Mersalyl; Pan troglodytes; Probenecid; Pyrazines; Uric Acid | 1975 |
Inhibition of urate excretion by pyrazinoate: a micropuncture study.
Topics: Animals; Carbon Radioisotopes; Female; Haplorhini; Infusions, Parenteral; Inulin; Kidney Tubules; Male; Mannitol; Probenecid; Pyrazines; Uric Acid | 1975 |
Diuretic-induced uricosuria: interaction with pyrazinoate transport in man.
Topics: Adult; Biological Transport, Active; Diuretics; Drug Interactions; Glomerular Filtration Rate; Glycolates; Humans; Kidney Tubules; Male; Phenoxyacetates; Pyrazines; Sodium; Thiophenes; Time Factors; Uric Acid; Uricosuric Agents | 1977 |
Nature of the uricosuric effect of tienilic acid, a new diuretic.
Topics: Animals; Chickens; Creatinine; Diuretics; Dogs; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Glycolates; Guinea Pigs; Kidney Glomerulus; Kidney Tubules; Mannitol; p-Aminohippuric Acid; Phenoxyacetates; Potassium; Pyrazines; Rabbits; Rats; Sodium; Thiophenes; Uric Acid; Uricosuric Agents | 1977 |
Observations on the reduction of the renal elimination of urate in man caused by the administration of pyrazinamide.
Topics: Humans; Male; Pyrazinamide; Pyrazines; Time Factors; Uric Acid | 1976 |
Renal excretion of urate in mongrel and Dalmatian dogs: a micropuncture study.
Topics: Animals; Bicarbonates; Dogs; Female; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Potassium; Pyrazines; Sodium; Species Specificity; Uric Acid | 1976 |
Bidirectional renal urate transport in the chimpanzee. Effects of drugs on secretory and reabsorptive fluxes.
Topics: Aminohippuric Acids; Animals; Biological Transport; Glomerular Filtration Rate; Kidney Tubules; Kidney Tubules, Distal; Male; Mersalyl; Pan troglodytes; Probenecid; Pyrazinamide; Pyrazines; Salicylates; Uric Acid; Uricosuric Agents | 1974 |
Tolerance and side-effects of the association hydrochlorothiazide-amiloride in long-term treatment of arterial hypertension.
Topics: Adult; Aged; Amiloride; Calcium; Creatinine; Drug Combinations; Drug Tolerance; Humans; Hydrochlorothiazide; Hypercalcemia; Hypertension; Hypocalcemia; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors; Urea; Uric Acid | 1974 |
Pharmacology of pyrazinamide: metabolic and renal function studies related to the mechanism of drug-induced urate retention.
Topics: Adsorption; Allopurinol; Animals; Biological Transport, Active; Biotransformation; Carboxylic Acids; Colorimetry; Dogs; Female; Filtration; Haplorhini; Humans; Inulin; Kidney; Kidney Function Tests; Kidney Tubules; Male; Metabolism; Pyrazinamide; Pyrazines; Uric Acid; Uricosuric Agents | 1972 |
[Level of blood serum level of uric acid in tuberculous patients treated with morphazinamide].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Humans; Male; Middle Aged; Morpholines; Pyrazines; Tuberculosis, Pulmonary; Uric Acid | 1973 |
Pyrazinoate excretion in the chimpanzee. Relation to urate disposition and the actions of uricosuric drugs.
Topics: Allopurinol; Aminohippuric Acids; Animals; Biological Transport; Carboxylic Acids; Chlorothiazide; Depression, Chemical; Glomerular Filtration Rate; Insulin; Iodopyracet; Kidney Tubules; Male; Organomercury Compounds; Pan troglodytes; Probenecid; Protein Binding; Pyrazines; Salicylates; Stimulation, Chemical; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 1973 |
A comparison of moduretic and hydrochlorothiazide in the treatment of hypertension in African patients.
Topics: Adult; Aged; Amiloride; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium Chloride; Pyrazines; Urea; Uric Acid | 1973 |
Functional characteristics of renal urate transport in the Cebus monkey.
Topics: Absorption; Aminohippuric Acids; Animals; Biological Transport; Dinitrophenols; Female; Glomerular Filtration Rate; Haplorhini; Hydroxybutyrates; Inulin; Kidney; Kidney Tubules; Lactates; Male; Probenecid; Pyrazines; Regional Blood Flow; Stimulation, Chemical; Uric Acid | 1970 |
Exchangeable potassium in heart disease: long-term effects of potassium supplements and amiloride.
Topics: Adult; Aged; Amiloride; Coronary Disease; Diuretics; Erythrocytes; Female; Furosemide; Heart Diseases; Heart Valve Diseases; Humans; Male; Middle Aged; Potassium; Potassium Isotopes; Pyrazines; Uric Acid | 1972 |
Studies on renal urate secretion in the dog.
Topics: Aminohippuric Acids; Animals; Carbon Isotopes; Chlormerodrin; Chlorothiazide; Dogs; Ethacrynic Acid; Female; Furosemide; Inulin; Kidney; Lactates; Male; Probenecid; Pyrazines; Renal Artery; Time Factors; Tritium; Uric Acid | 1971 |
[Uricosuric effect of benzbromaronum on a model of pyrazine amide-induced hyperuricemia].
Topics: Adult; Benzofurans; Female; Humans; Ketones; Kidney; Male; Middle Aged; Models, Biological; Pyrazines; Uremia; Uric Acid; Uricosuric Agents | 1970 |
Renal urate transport in the chimpanzee.
Topics: Aminohippuric Acids; Animals; Creatinine; Diuresis; Glomerular Filtration Rate; Hominidae; Inulin; Kidney; Kidney Function Tests; Kidney Tubules; Male; Osmolar Concentration; Phlorhizin; Probenecid; Pyrazines; Spectrophotometry; Uric Acid | 1971 |
Renal transport of uric acid in the guinea pig.
Topics: Absorption; Animals; Biological Transport; Chlorothiazide; Depression, Chemical; Female; Guinea Pigs; Inulin; Kidney Tubules; Lactates; Male; Ouabain; Probenecid; Pyrazines; Uric Acid | 1968 |
Renal excretion of uric acid in the dog.
Topics: Animals; Biological Transport, Active; Creatinine; Dogs; Female; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Inulin; Kidney; Kidney Tubules; Probenecid; Pyrazines; Species Specificity; Uric Acid | 1968 |
[Latest observations in man experimental animals on hepatic function, gastric secretion and blood uric acid in the course of therapy with morphazinamide].
Topics: Animals; Antitubercular Agents; Blood; Gastric Juice; Guinea Pigs; Humans; Liver; Pyrazines; Tuberculosis, Pulmonary; Uric Acid | 1965 |
Effects of MK-870 in normal subjects and hypertensive patients.
Topics: Adult; Aged; Amidines; Blood Urea Nitrogen; Creatine; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Sodium; Uric Acid | 1966 |
Clinical trial of a potassium-sparing saluretic pyrazine derivative (MK-870).
Topics: Adult; Aged; Carbon Dioxide; Chlorides; Creatine; Diuretics; Edema; Female; Heart Failure; Humans; Liver Cirrhosis; Male; Middle Aged; Potassium; Pyrazines; Sodium; Uric Acid | 1967 |
Prevention of calcium nephrolithiasis with low-dose thiazide, amiloride and allopurinol.
Topics: Adult; Allopurinol; Amiloride; Calcium; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Pyrazines; Uric Acid | 1981 |
A fixed combination of hydrochlorothiazide and amiloride for the treatment of essential hypertension.
Topics: Adolescent; Adult; Aged; Amiloride; Blood Chemical Analysis; Blood Pressure; Body Weight; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Male; Middle Aged; Pyrazines; Uric Acid | 1980 |
Treatment possibility of hypercholesterolaemia associated with hypertriglyceridaemia.
Topics: Apolipoprotein A-I; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemias; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins, LDL; Male; Middle Aged; Pyrazines; Time Factors; Triglycerides; Uric Acid | 1997 |
STOP-FLOW ANALYSIS OF TUBULAR TRANSPORT OF URIC ACID IN RABBITS.
Topics: Animals; Biological Transport; Body Fluids; Chlorothiazide; Creatine; Creatinine; Glomerular Filtration Rate; Inulin; Kidney Tubules; Lactates; Metabolism; Pharmacology; Physiology; Probenecid; Pyrazines; Rabbits; Research; Salicylates; Uric Acid; Urine | 1964 |
Mercaptoethylpyrazine promoted electrochemistry of redox protein and amperometric biosensing of uric acid.
Topics: Biosensing Techniques; Electrochemistry; Electrodes; Enzymes, Immobilized; Gold; Hydrogen Peroxide; Models, Molecular; Molecular Structure; Oxidation-Reduction; Peroxidases; Polymers; Pyrazines; Sulfhydryl Compounds; Uric Acid | 2007 |
Determination of uric acid in serum using an optical sensor based on binuclear Pd(II) 2-pyrazinecarboxamide-bipyridine doped in a sol gel matrix.
Topics: 2,2'-Dipyridyl; Carcinoma, Hepatocellular; Cardiovascular Diseases; Coordination Complexes; Gels; Humans; Liver Neoplasms; Optical Devices; Optical Imaging; Palladium; Pyrazines; Uric Acid | 2019 |
Acute Gouty Arthritis During Favipiravir Treatment for Coronavirus Disease 2019.
Topics: Adult; Amides; Antiviral Agents; Arthritis, Gouty; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Hyperuricemia; Lung; Male; Pandemics; Pneumonia, Viral; Pyrazines; SARS-CoV-2; Uric Acid | 2020 |
Elevated blood favipiravir levels are inversely associated with ferritin levels and induce the elevation of uric acid levels in COVID-19 treatment: A retrospective single-center study.
Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; Ferritins; Humans; Pyrazines; Retrospective Studies; SARS-CoV-2; Uric Acid | 2022 |
Baseline uric acid levels and steady-state favipiravir concentrations are associated with occurrence of hyperuricemia among COVID-19 patients.
Topics: Amides; COVID-19; Humans; Hyperuricemia; Pyrazines; SARS-CoV-2; Uric Acid | 2022 |
Evaluation of risk factors for uric acid elevation in COVID-19 patients treated with favipiravir.
Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Pyrazines; Retrospective Studies; Risk Factors; SARS-CoV-2; Treatment Outcome; Uric Acid | 2022 |