uric acid and peroxynitrous acid

uric acid has been researched along with peroxynitrous acid in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.79)	18.2507
2000's	44 (78.57)	29.6817
2010's	10 (17.86)	24.3611
2020's	1 (1.79)	2.80

Authors

Authors	Studies
Anjos, EI; Augusto, O; Santos, CX	1
Cueto, R; Pryor, WA; Splenser, AE; Squadrito, GL; Uppu, RM; Valavanidis, A; Zhang, H	1
Bette, M; Dietzschold, B; Hooper, DC; Kean, RB; Mikheeva, T; Morimoto, K; Röhrenbeck, AM; Scott, GS; Spitsin, SV; Weihe, E	1
Hooper, DC; Koprowskil, H; Leist, T; Mikheeva, T; Spitsin, S; Streletz, LJ	1
Halliwell, B; Ketsawatsakul, U; Whiteman, M	1
Bryner, KD; Christie, I; Ganser, G; Hobbs, GR; Hoeldtke, RD; McNeill, DR; Riggs, JE; Van Dyke, K; Warehime, SS	1
Laude, K; Richard, V; Thuillez, C	1
Garthwaite, J; Griffiths, C; Keynes, RG	1
Beckman, JS; Parks, DA; Teng, RJ; Ye, YZ	1
Brimer, CM; Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV; Zborek, A	1
Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV	1
Golfetti, R; Merrill, G; Rork, T; Spiler, N; VanDyke, K	1
Buoncristiani, U; Canestrari, F; Davenport, A; Ferraro, B; Frei, B; Galli, F; Kingdon, E; Moore, KP; Rice-Evans, C	1
Abou-Mohamed, G; Behzadian, MA; Caldwell, RB; Caldwell, RW; El-Remessy, AB; Franklin, T	1
Gounarides, JS; Lee, WH; Roos, ES; Wolin, MS	1
Devaraj, S; Jialal, I; Venugopal, SK	1
Kanzýk, Y; Tecder-Unal, M	1
Batinić-Haberle, I; Batthyány, C; Botti, H; Ferrer-Sueta, G; Radi, R; Rubbo, H; Trostchansky, A	1
Bezerra, MM; Brain, SD; da Rocha, FA; de Melo, LB; Greenacre, S; Jerônimo, SM; Keeble, J	1
Hisatomi, T; Ishibashi, T; Ito, S; Kimoto, T; Rao, NA; Wu, GS	1
Deen, WM; Wang, C	1
Beckman, JS; Morré, JT; Robinson, KM	1
Millar, TM	1
Bubolz, A; Gutterman, DD; Li, H; Liu, Y; Rusch, NJ	1
Brimer, CM; Fabis, MJ; Hooper, DC; Kean, RB; Mikheeva, T; Phares, TW; Scott, GS; Spitsin, SV	1
Ayala, DE; Bremner, WF; Foley, S; Hermida, RC; Hooper, DC; Johnson, MC; Kanabrocki, EL; Murray, D; Nemchausky, BA; Ryan, MD; Scott, GS; Shah, F; Shirazi, P; Third, JL; Van Cauteren, J	1
Cuzzocrea, S; Genovese, T; Hooper, DC; Koprowski, H; Scott, GS	1
Dikalov, S; Harrison, DG; Kuzkaya, N; Weissmann, N	1
Faraci, F; Heistad, D; Ohashi, M	1
Gertzberg, N; Johnson, A; Lambert, W; Neumann, P; Vaughan, E; Weisbrot, J; Woodburn, R	1
Chang, KH; Jeon, EJ; Lee, SK; Park, SN; Park, YS; Yeo, SW	1
Doke, N; Kawakita, K; Saito, S; Yamamoto-Katou, A; Yoshioka, H	1
Christopher, TA; Gao, F; Guo, WY; Li, QX; Lopez, BL; Ma, XL; Su, H; Wang, HC; Yan, W; Zhang, HF; Zhang, KR	1
Chen, JG; Liu, YH; Shu, BH; Wang, JZ; Xu, YF; Yin, J; Zhang, YJ	1
Demiryürek, AT; Turan, NN	1
Colantuono, G; Khan, M; Kumbala, D; Kuppusamy, P; Kutala, VK; Mandal, R; Potaraju, V	1
Bezerra, MM; Brain, SD; Girão, VC; Greenacre, S; Keeble, J; Rocha, FA	1
Alves-Filho, JC; Celes, MR; Cunha, FQ; Dal-Secco, D; Dalto, VF; Ferreira, SH; Freitas, A; Rossi, MA; Spiller, F; Torres-Dueñas, D	1
Firestein, BL; Kutzing, MK	1
Demiryurek, AT; Gumusel, B; Turan, NN; Yildiz, G	1
Fatokun, AA; Smith, RA; Stone, TW	1
Angerhofer, A; Gersch, C; Henderson, GN; Johnson, RJ; Kim, KM; Palii, SP	1
Angerhofer, A; Gersch, C; Henderson, GN; Imaram, W; Johnson, RJ; Karumanchi, SA; Kim, KM; Palii, SP	1
Bolton, C; Flower, RJ; Scott, GS; Wood, EG	1
Duan, H; Li, Y; Liu, H; Liu, Q; Liu, S; Shi, Y; Wang, H; Wang, XM	1
Berson, A; Fromenty, B; Huang, TT; Larosche, I; Lettéron, P; Mansouri, A; Moreau, R; Pessayre, D	1
Bisana, S; Chatterjee, S; Illavazagan, G; Kolluru, GK; Mahajan, S; Majumder, S; Muley, A; Seerapu, Hb; Siamwala, JH; Sinha, S; Subramaniam, GP	1
Angerhofer, A; Gersch, C; Henderson, GN; Imaram, W; Johnson, RJ; Kim, KM	1
Delledonne, M; Gaupels, F; Spiazzi-Vandelle, E; Yang, D	1
Juhász, L; Kaszaki, J; Kiss, A; Kovács, M; Nyeso, E; Seprényi, G; Végh, A	1
Chen, Y; Cheng, R; Hu, Y; Lee, K; Li, J; Liu, Q; Liu, Z; Ma, JX; Yi, J	1
Hao, MW; Hu, ZT; Qin, XL; Sun, L; Zhang, QS	1
Miyazaki, Y; Nagase, M; Yamamoto, Y; Yoshino, H	1
Fujisawa, A; Yamamoto, Y	1
Lee, CT; Wang, JY; Yu, LE	1
Ozawa-Tamura, A; Sasabe, Y; Suzuki, T; Takeuchi, M	1

Reviews

1 review(s) available for uric acid and peroxynitrous acid

Article	Year
Altered uric acid levels and disease states. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:1 Topics: Animals; Cardiovascular Diseases; Gout; Humans; Hypertension; Hyperuricemia; Inflammation; Kidney Diseases; Neurons; Peroxynitrous Acid; Uric Acid	2008

Trials

2 trial(s) available for uric acid and peroxynitrous acid

Article	Year
Inactivation of peroxynitrite in multiple sclerosis patients after oral administration of inosine may suggest possible approaches to therapy of the disease. Multiple sclerosis (Houndmills, Basingstoke, England), 2001, Volume: 7, Issue:5 Topics: Administration, Oral; Adult; Female; Gadolinium; Humans; Inosine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Peroxynitrous Acid; Uric Acid	2001
Increased oxidative stress in patients with amyotrophic lateral sclerosis and the effect of edaravone administration. Redox report : communications in free radical research, 2016, Volume: 21, Issue:3 Topics: Aged; Amyotrophic Lateral Sclerosis; Antipyrine; Biomarkers; Edaravone; Fatty Acids, Nonesterified; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Ubiquinone; Uric Acid	2016

Article

Year

Inactivation of peroxynitrite in multiple sclerosis patients after oral administration of inosine may suggest possible approaches to therapy of the disease.

Multiple sclerosis (Houndmills, Basingstoke, England), 2001, Volume: 7, Issue:5

Topics: Administration, Oral; Adult; Female; Gadolinium; Humans; Inosine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Peroxynitrous Acid; Uric Acid

2001

Increased oxidative stress in patients with amyotrophic lateral sclerosis and the effect of edaravone administration.

Redox report : communications in free radical research, 2016, Volume: 21, Issue:3

Topics: Aged; Amyotrophic Lateral Sclerosis; Antipyrine; Biomarkers; Edaravone; Fatty Acids, Nonesterified; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Ubiquinone; Uric Acid

2016

Other Studies

53 other study(ies) available for uric acid and peroxynitrous acid

Article	Year
Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation. Archives of biochemistry and biophysics, 1999, Dec-15, Volume: 372, Issue:2 Topics: Allantoin; Alloxan; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lipid Metabolism; Lipid Peroxides; Lipoproteins, LDL; Liposomes; Nitrates; Nitrous Acid; Oxidants; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Thiobarbituric Acid Reactive Substances; Uric Acid	1999
Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid. Archives of biochemistry and biophysics, 2000, Apr-15, Volume: 376, Issue:2 Topics: Bicarbonates; Carbon Dioxide; Free Radical Scavengers; Free Radicals; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Neuroprotective Agents; Nitrates; Nitrogen Dioxide; Nitrous Acid; Oxidants; Peroxynitrous Acid; Temperature; Uric Acid	2000
The central nervous system inflammatory response to neurotropic virus infection is peroxynitrite dependent. Journal of immunology (Baltimore, Md. : 1950), 2001, Sep-15, Volume: 167, Issue:6 Topics: Acute Disease; Animals; Antigens, Viral; Blood-Brain Barrier; Borna Disease; Borna disease virus; Brain; Brain Chemistry; Chemotaxis, Leukocyte; Encephalitis, Viral; Female; Free Radical Scavengers; Free Radicals; Gene Expression Profiling; Immunocompetence; Inflammation; Lymphocyte Count; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Peroxynitrous Acid; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; T-Lymphocyte Subsets; Tyrosine; Uric Acid; Virus Replication	2001
A reassessment of the peroxynitrite scavenging activity of uric acid. Annals of the New York Academy of Sciences, 2002, Volume: 962 Topics: alpha 1-Antitrypsin; Antioxidants; Ascorbic Acid; Benzothiazoles; Bicarbonates; Chromans; Coloring Agents; Glutathione; Guanine; Humans; Indicators and Reagents; Peroxynitrous Acid; Pyrogallol; Reactive Nitrogen Species; Serine Proteinase Inhibitors; Sulfonic Acids; Tyrosine; Uric Acid	2002
Nitrosative stress, uric Acid, and peripheral nerve function in early type 1 diabetes. Diabetes, 2002, Volume: 51, Issue:9 Topics: Adolescent; Adult; Autonomic Nervous System; Child; Diabetes Mellitus, Type 1; Dinoprost; F2-Isoprostanes; Female; Heart Conduction System; Humans; Male; Motor Neurons; Neural Conduction; Nitrates; Nitrites; Peripheral Nerves; Peroxynitrous Acid; Reference Values; Sweating; Time Factors; Tyrosine; Uric Acid	2002
Peroxynitrite triggers a delayed resistance of coronary endothelial cells against ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4 Topics: Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Ischemic Preconditioning, Myocardial; Male; Methionine; Molsidomine; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Peroxynitrous Acid; Rats; Rats, Wistar; Selenomethionine; Uric Acid	2002
Superoxide-dependent consumption of nitric oxide in biological media may confound in vitro experiments. The Biochemical journal, 2003, Jan-15, Volume: 369, Issue:Pt 2 Topics: Animals; Azo Compounds; Cells, Cultured; Chelating Agents; Culture Media; HEPES; Light; Nitric Oxide; Peroxynitrous Acid; Riboflavin; Signal Transduction; Superoxide Dismutase; Superoxides; Uric Acid	2003
Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration. Free radical biology & medicine, 2002, Nov-01, Volume: 33, Issue:9 Topics: Animals; Ascorbic Acid; Brain; Heart; Hypoxanthine; Hypoxia; In Vitro Techniques; Myocardium; Nitric Oxide; Nitrosation; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tyrosine; Urate Oxidase; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase	2002
Comparison of uric acid and ascorbic acid in protection against EAE. Free radical biology & medicine, 2002, Nov-15, Volume: 33, Issue:10 Topics: Albumins; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Cell Line; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Immunohistochemistry; Iron; Lipid Peroxidation; Mice; Molsidomine; Myelin Sheath; Nitric Oxide; Oxygen; Peroxynitrous Acid; Rhodamines; Time Factors; Tyrosine; Uric Acid	2002
Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors. Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-10, Volume: 99, Issue:25 Topics: Administration, Oral; Animals; Biotransformation; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inosine; Inosine Monophosphate; Mice; Molsidomine; Monocytes; Multiple Sclerosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Oxonic Acid; Peroxynitrous Acid; Urate Oxidase; Uric Acid; Xanthines	2002
Acetaminophen in the post-ischemia reperfused myocardium. Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:11 Topics: Acetaminophen; Animals; Creatine Kinase; Female; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Peroxynitrous Acid; Uric Acid	2002
Peroxynitrite-induced oxidation of plasma lipids is enhanced in stable hemodialysis patients. Kidney international, 2003, Volume: 63, Issue:6 Topics: Adult; Aged; Aged, 80 and over; F2-Isoprostanes; Female; Humans; Kidney Failure, Chronic; Lipids; Male; Membranes, Artificial; Middle Aged; Molsidomine; Nitric Oxide Donors; Oxidation-Reduction; Peroxynitrous Acid; Renal Dialysis; Tocopherols; Uric Acid	2003
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor. The American journal of pathology, 2003, Volume: 162, Issue:6 Topics: Animals; Blood-Retinal Barrier; Body Weight; Diabetes Mellitus, Experimental; Endothelial Growth Factors; Enzyme Inhibitors; Gene Expression; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Lymphokines; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Retina; RNA, Messenger; Tyrosine; Uric Acid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2003
Influence of peroxynitrite on energy metabolism and cardiac function in a rat ischemia-reperfusion model. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:4 Topics: Animals; beta-Galactosidase; Cardiotonic Agents; Cell Membrane; Creatine Kinase; Energy Metabolism; Heart; In Vitro Techniques; Lactase; Magnetic Resonance Spectroscopy; Male; Myocardium; Nitric Oxide; Nitroarginine; Oxygen Consumption; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Uric Acid	2003
C-reactive protein decreases prostacyclin release from human aortic endothelial cells. Circulation, 2003, Oct-07, Volume: 108, Issue:14 Topics: Aorta; Ascorbic Acid; C-Reactive Protein; Cells, Cultured; Coronary Vessels; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Epoprostenol; Free Radical Scavengers; Humans; Intramolecular Oxidoreductases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Prostaglandins F; Tyrosine; Uric Acid	2003
Peroxynitrite in reperfusion arrhythmias and its whole blood chemiluminescence results. Pharmacological research, 2004, Volume: 49, Issue:1 Topics: Animals; Blood Pressure; Catalase; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Free Radical Scavengers; Heart Rate; Infusions, Intravenous; Luminescent Measurements; Male; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tachycardia, Ventricular; Uric Acid; Ventricular Fibrillation; Vision, Ocular	2004
Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid. Free radical biology & medicine, 2003, Nov-15, Volume: 35, Issue:10 Topics: alpha-Tocopherol; gamma-Tocopherol; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Manganese; Metalloporphyrins; Nitrogen Dioxide; Oxidation-Reduction; Peroxynitrous Acid; Uric Acid	2003
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis. British journal of pharmacology, 2004, Volume: 141, Issue:1 Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycosaminoglycans; Guanidines; Injections, Intra-Articular; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Synovial Membrane; Synovitis; Tyrosine; Uric Acid; Zymosan	2004
Peroxynitrite-induced apoptosis in photoreceptor cells. Current eye research, 2004, Volume: 28, Issue:1 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; DNA; Immunohistochemistry; In Situ Nick-End Labeling; Molsidomine; Nitric Oxide Donors; Peroxynitrous Acid; Photoreceptor Cells, Vertebrate; Rats; Rats, Inbred Lew; Uric Acid	2004
Peroxynitrite delivery methods for toxicity studies. Chemical research in toxicology, 2004, Volume: 17, Issue:1 Topics: Animals; Cells, Cultured; Dimerization; Drug Delivery Systems; Humans; Hypoxanthine; Models, Chemical; Nitrates; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Toxicity Tests; Tyrosine; Uric Acid; Xanthine Oxidase	2004
Triuret: a novel product of peroxynitrite-mediated oxidation of urate. Archives of biochemistry and biophysics, 2004, Mar-01, Volume: 423, Issue:1 Topics: Mass Spectrometry; Oxidation-Reduction; Peroxynitrous Acid; Urea; Uric Acid	2004
Peroxynitrite formation from the simultaneous reduction of nitrite and oxygen by xanthine oxidase. FEBS letters, 2004, Mar-26, Volume: 562, Issue:1-3 Topics: Animals; Cattle; Enzyme Inhibitors; Milk; Nitric Oxide; Nitrites; Onium Compounds; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Rhodamines; Superoxide Dismutase; Uric Acid; Xanthine Oxidase	2004
Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose. Diabetes, 2004, Volume: 53, Issue:9 Topics: Animals; Azoles; Coronary Vessels; Free Radical Scavengers; Glucose; Isoindoles; Male; Membrane Potentials; Microcirculation; Nitrogen; Organoselenium Compounds; Patch-Clamp Techniques; Peroxynitrous Acid; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Uric Acid; Vasodilation	2004
ICAM-1 upregulation in the spinal cords of PLSJL mice with experimental allergic encephalomyelitis is dependent upon TNF-alpha production triggered by the loss of blood-brain barrier integrity. Journal of neuroimmunology, 2004, Volume: 155, Issue:1-2 Topics: Animals; Blood-Brain Barrier; Chemotaxis, Leukocyte; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Endothelium, Vascular; Female; Free Radical Scavengers; Free Radicals; Intercellular Adhesion Molecule-1; Mice; Myelin Basic Protein; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Spinal Cord; Tumor Necrosis Factor-alpha; Up-Regulation; Uric Acid	2004
Altered circadian relationship between serum nitric oxide, carbon dioxide, and uric acid in multiple sclerosis. Chronobiology international, 2004, Volume: 21, Issue:4-5 Topics: Adult; Aged; Carbon Dioxide; Case-Control Studies; Circadian Rhythm; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Nitric Oxide; Peroxynitrous Acid; Reference Values; Uric Acid	2004
Uric acid protects against secondary damage after spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America, 2005, Mar-01, Volume: 102, Issue:9 Topics: Animals; Cells, Cultured; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Neurons; Neutrophils; Peroxidase; Peroxynitrous Acid; Spinal Cord Injuries; Uric Acid	2005
Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase. Biochemical pharmacology, 2005, Aug-01, Volume: 70, Issue:3 Topics: Animals; Ascorbic Acid; Cattle; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Sulfhydryl Compounds; Uncoupling Agents; Uric Acid	2005
Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid artery in rabbit via ATP-sensitive K+ channels. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:5 Topics: Animals; Antioxidants; Azoles; Carotid Artery, Internal; Catalase; Charybdotoxin; Glyburide; Hydrogen Peroxide; Hypoglycemic Agents; In Vitro Techniques; Isoindoles; Male; Membrane Potentials; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Organoselenium Compounds; Peroxynitrous Acid; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Rabbits; Reactive Oxygen Species; Superoxide Dismutase; Tetraethylammonium Compounds; Uric Acid	2005
Peroxynitrite mediates TNF-alpha-induced endothelial barrier dysfunction and nitration of actin. American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:4 Topics: Actins; Albumins; Animals; Capillary Permeability; Cattle; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Lung; Microcirculation; Nitrates; Peroxynitrous Acid; Protein Isoforms; Rats; Tissue Distribution; Tumor Necrosis Factor-alpha; Tyrosine; Uric Acid	2006
Effect of nitric oxide and peroxynitrite on mucociliary transport function of experimental otitis media. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 134, Issue:1 Topics: Animals; Disease Models, Animal; Free Radical Scavengers; Guinea Pigs; Lipopolysaccharides; Mucociliary Clearance; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Otitis Media with Effusion; Peroxynitrous Acid; Pseudomonas aeruginosa; Uric Acid	2006
Peroxynitrite generation and tyrosine nitration in defense responses in tobacco BY-2 cells. Plant & cell physiology, 2006, Volume: 47, Issue:6 Topics: Algal Proteins; Aniline Compounds; Antibodies, Anti-Idiotypic; Cells, Cultured; Cyclic GMP; Fluoresceins; Fungal Proteins; Molsidomine; Nicotiana; Nitric Oxide; Peroxynitrous Acid; Phytophthora; Proteins; Reactive Oxygen Species; Superoxides; Tyrosine; Uric Acid	2006
Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: role of peroxynitrite formation. Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:8 Topics: Animals; Apoptosis; Cell Survival; Hypoxia; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxygen; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Uric Acid	2006
Melatonin arrests peroxynitrite-induced tau hyperphosphorylation and the overactivation of protein kinases in rat brain. Journal of pineal research, 2006, Volume: 41, Issue:2 Topics: Animals; Glycogen Synthase Kinase 3; Hippocampus; Male; Melatonin; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Phosphorylation; Rats; Rats, Wistar; Superoxide Dismutase; tau Proteins; Uric Acid	2006
Preconditioning effects of peroxynitrite in the rat lung. Pharmacological research, 2006, Volume: 54, Issue:5 Topics: Animals; Benzamides; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning; Lung; Male; Malondialdehyde; Niacinamide; Peroxynitrous Acid; Phenylephrine; Poly(ADP-ribose) Polymerase Inhibitors; Potassium Chloride; Rats; Rats, Wistar; Reperfusion Injury; Uric Acid	2006
Prevention of postischemic myocardial reperfusion injury by the combined treatment of NCX-4016 and Tempol. Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:3 Topics: Animals; Aspirin; Creatine Kinase; Cyclic N-Oxides; L-Lactate Dehydrogenase; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxide Dismutase; Superoxides; Uric Acid	2006
Neutrophils-derived peroxynitrite contributes to acute hyperalgesia and cell influx in zymosan arthritis. Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 374, Issue:4 Topics: Acute Disease; Animals; Arthritis, Experimental; Hindlimb; Hyperalgesia; Injections, Intra-Articular; Knee Joint; Male; Neutrophils; Nitric Oxide; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Tyrosine; Uric Acid; Zymosan	2007
Peroxynitrite mediates the failure of neutrophil migration in severe polymicrobial sepsis in mice. British journal of pharmacology, 2007, Volume: 152, Issue:3 Topics: Animals; Antioxidants; Cecum; Cell Adhesion; Cell Movement; Cytokines; Disease Models, Animal; Ligation; Male; Mesentery; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Peroxynitrous Acid; Punctures; Sepsis; Severity of Illness Index; Survival Rate; Uric Acid	2007
Ischemic and peroxynitrite preconditioning effects in chronic hypoxic rat lung. Experimental lung research, 2008, Volume: 34, Issue:6 Topics: Animals; Chronic Disease; Drug Antagonism; Drug Therapy, Combination; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Ischemic Preconditioning; Lung; Organ Size; Perfusion; Peroxynitrous Acid; Poly(ADP-ribose) Polymerase Inhibitors; Potassium Chloride; Rats; Reperfusion Injury; Uric Acid	2008
Prolonged exposures of cerebellar granule neurons to S-nitroso-N-acetylpenicillamine (SNAP) induce neuronal damage independently of peroxynitrite. Brain research, 2008, Sep-16, Volume: 1230 Topics: Animals; Cell Death; Cell Survival; Cerebellum; Cyclosporine; Cytoplasmic Granules; Data Interpretation, Statistical; Free Radical Scavengers; Hemoglobins; Hydroquinones; Melatonin; Mitochondrial Membranes; Neurons; Nitric Oxide Donors; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Uric Acid	2008
Inactivation of nitric oxide by uric acid. Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:8 Topics: Cardiovascular Diseases; Chromatography, Liquid; Endothelial Cells; Glutathione; Humans; Hydrogen Peroxide; Mass Spectrometry; Molecular Structure; Nitric Oxide; Peroxynitrous Acid; Uracil; Uric Acid	2008
Reactions of peroxynitrite with uric acid: formation of reactive intermediates, alkylated products and triuret, and in vivo production of triuret under conditions of oxidative stress. Nucleosides, nucleotides & nucleic acids, 2009, Volume: 28, Issue:2 Topics: Antioxidants; Female; Humans; Hyperuricemia; Oxidants; Oxidative Stress; Peroxynitrous Acid; Pre-Eclampsia; Pregnancy; Urea; Uric Acid	2009
A comparative evaluation of the response to peroxynitrite by a brain endothelial cell line and control of the effects by drug targeting. Cellular and molecular neurobiology, 2009, Volume: 29, Issue:5 Topics: Animals; Brain; Cell Adhesion; Cell Adhesion Molecules; Cell Death; Cell Line; Drug Delivery Systems; Drug Resistance; Endothelial Cells; Metalloporphyrins; Mice; Peroxynitrous Acid; Phenanthrenes; T-Lymphocytes; Tumor Necrosis Factor-alpha; Uric Acid	2009
Peroxynitrite mediates glomerular lesion of diabetic rat via JAK/STAT signaling pathway. Journal of endocrinological investigation, 2009, Volume: 32, Issue:10 Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Immunohistochemistry; Janus Kinase 2; Kidney Glomerulus; Male; Microscopy, Electron, Transmission; Peroxynitrous Acid; Phosphorylation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Transforming Growth Factor beta; Tyrosine; Uric Acid	2009
Hepatic mitochondrial DNA depletion after an alcohol binge in mice: probable role of peroxynitrite and modulation by manganese superoxide dismutase. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:3 Topics: Animals; Caspase 3; Cyclic N-Oxides; DNA-Binding Proteins; DNA, Mitochondrial; Electron Transport Complex I; Ethanol; Free Radical Scavengers; Glutathione Peroxidase; High Mobility Group Proteins; Iron; Liver; Mice; Mice, Knockout; Mitochondria, Liver; Mitochondrial Proton-Translocating ATPases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Reactive Oxygen Species; Spin Labels; Superoxide Dismutase; Transcription Factors; Uric Acid	2010
Inhibition of dynamin-2 confers endothelial barrier dysfunctions by attenuating nitric oxide production. Cell biology international, 2010, Volume: 34, Issue:7 Topics: Antioxidants; Capillary Permeability; Cell Line; Dynamin II; Endothelial Cells; Endothelium, Vascular; Humans; Hypoxia; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroprusside; Peroxynitrous Acid; Uric Acid	2010
Radicals in the reaction between peroxynitrite and uric acid identified by electron spin resonance spectroscopy and liquid chromatography mass spectrometry. Free radical biology & medicine, 2010, Jul-15, Volume: 49, Issue:2 Topics: Chemical Phenomena; Chromatography, Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; In Vitro Techniques; Mass Spectrometry; Models, Chemical; Oxidation-Reduction; Peroxynitrous Acid; Protein Carbonylation; Uric Acid	2010
Detection of peroxynitrite accumulation in Arabidopsis thaliana during the hypersensitive defense response. Nitric oxide : biology and chemistry, 2011, Aug-01, Volume: 25, Issue:2 Topics: Aniline Compounds; Arabidopsis; Bacterial Proteins; Boron Compounds; Fluoresceins; Molsidomine; Nitric Oxide; Peroxynitrous Acid; Photometry; Plant Diseases; Plant Leaves; Protein Processing, Post-Translational; Pseudomonas syringae; Signal Transduction; Tyrosine; Uric Acid	2011
Is there a trigger role of peroxynitrite in the anti-arrhythmic effect of ischaemic preconditioning and peroxynitrite infusion? European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Vessels; Dogs; Female; Heart Ventricles; Hemodynamics; Hydrogen-Ion Concentration; Infusions, Intra-Arterial; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Nitrates; Nitrites; Peroxynitrous Acid; Superoxides; Time Factors; Tyrosine; Uric Acid	2011
Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy. Antioxidants & redox signaling, 2013, Apr-01, Volume: 18, Issue:10 Topics: Aldehydes; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Glucose; Peroxynitrous Acid; Signal Transduction; Uric Acid; Wnt Signaling Pathway	2013
Lower Serum Bilirubin and Uric Acid Concentrations in Patients with Parkinson's Disease in China. Cell biochemistry and biophysics, 2015, Volume: 72, Issue:1 Topics: Aged; Aged, 80 and over; Antioxidants; Asian People; Bilirubin; Case-Control Studies; China; Dopamine; Dose-Response Relationship, Drug; Female; Free Radicals; Humans; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Peroxynitrous Acid; Substantia Nigra; Uric Acid	2015
Edaravone, a potent free radical scavenger, reacts with peroxynitrite to produce predominantly 4-NO-edaravone. Redox report : communications in free radical research, 2016, Volume: 21, Issue:3 Topics: Antipyrine; Edaravone; Free Radical Scavengers; Lipid Peroxidation; Neuroprotective Agents; Oxidation-Reduction; Peroxynitrous Acid; Uric Acid	2016
Nitroxide antioxidant as a potential strategy to attenuate the oxidative/nitrosative stress induced by hydrogen peroxide plus nitric oxide in cultured neurons. Nitric oxide : biology and chemistry, 2016, Apr-01, Volume: 54 Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cyclic N-Oxides; Hydrogen Peroxide; L-Lactate Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Thiourea; Uric Acid	2016
Uric Acid as a Photosensitizer in the Reaction of Deoxyribonucleosides with UV Light of Wavelength Longer than 300 nm: Identification of Products from 2'-Deoxycytidine. Chemical & pharmaceutical bulletin, 2021, Volume: 69, Issue:11 Topics: Bromates; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; DNA; Ethanol; Free Radical Scavengers; Hypochlorous Acid; Kinetics; Peroxynitrous Acid; Photochemical Processes; Photosensitizing Agents; Singlet Oxygen; Sodium Azide; Thymidine; Ultraviolet Rays; Uric Acid	2021