uric acid has been researched along with mercaptopurine in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (64.15) | 18.7374 |
| 1990's | 10 (18.87) | 18.2507 |
| 2000's | 4 (7.55) | 29.6817 |
| 2010's | 5 (9.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuchs, D; Hermann, J; Plenert, W; Zintl, F | 1 |
| Salemnick, G; Stöhrer, G | 1 |
| Chalmers, AH | 1 |
| Iven, H; Kurowski, V | 1 |
| Leclerc, JM; Lin, KT; Rivard, GE; Varin, F | 1 |
| Canafax, DM; Chan, GL; Erdmann, GR; Gruber, SA; Matas, AJ | 1 |
| Ascher, NL; Canafax, DM; Chan, GL; Chen, S; Erdmann, GR; Gruber, SA; Stock, P | 1 |
| Bruunshuus, I; Schmiegelow, K | 1 |
| Diadyk, AI; Nikolenko, IuI; Shpilevaia, NI; Siniachenko, OV; Vasilenko, IV | 1 |
| Johnson, CA; Porter, WR; Vanscoik, KG | 1 |
| Krakoff, IH | 1 |
| Burry, HC | 1 |
| Lampkin, B; Mauer, AM; McWilliams, NB | 1 |
| Jezewska, MM | 1 |
| Greenwald, ES | 1 |
| Armata, J | 1 |
| Burrs, AT; Dennis, MJ; Lewis, RW | 1 |
| Brune, K; Floersheim, GL; Seiler, K | 1 |
| Atkinson, MR; Chalmers, AH; Knight, PR | 2 |
| Dano, K; Nissen, NI | 1 |
| Hitchings, GH | 1 |
| Gault, MH; Hebert, MA; Singh, HP | 1 |
| Benke, PJ; Herrick, N | 1 |
| Elion, GB | 1 |
| Maher, JF; Rath, CE; Schreiner, GE | 1 |
| al-Rashid, RA; Call, JE | 1 |
| Friedman, PA | 1 |
| Freireich, EJ | 1 |
| Hirose, S; Takeshima, S; Tawa, R | 1 |
| Bronk, JR; Pennington, AM | 1 |
| Downs, SM | 1 |
| Jeebhay, M; Mbuli, S; Uebel, R | 1 |
| Elfarra, AA; Hwang, IY | 1 |
| Gossmann, J; Rietbrock, N; Scheuermann, EH; Thürmann, P; Weller, S | 1 |
| Evans, WE; Harrison, PL; Lascombes, F; Mahmoud, HH; Mondesir, JM; Pui, CH; Relling, MV; Ribeiro, RC; Rivera, GK; Sandlund, JT; Struxiano, A | 1 |
| Balogh, A; Bruckner, G; Kósa, E; Medveczky, I; Szabó, J | 1 |
| Hsia, SH; Hsueh, C; Hung, IJ; Jaing, TH; Kao, CC; Tain, YL | 1 |
| BRASCHI, A; CERRI, O | 1 |
| DUGGAN, DE; TITUS, E | 1 |
| MEYERS, MC; PENNER, JA; WEINTRAUB, LR | 1 |
| JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
| KORNACKA, L; MALEC, J; WOJNAROWSKA, M; ZAKRZEWSKI, K | 1 |
| Jena, G; Kalra, S; Mukhopadhyay, AK; Tikoo, K | 1 |
| Ansari, A; Aslam, Z; De Sica, A; Duley, J; Fairbanks, L; Gilshenan, K; Marinaki, A; Sanderson, J; Smith, M | 1 |
| Cairns, C; Collier, PS; Dempsey, S; Hawwa, AF; McCarthy, A; McElnay, JC; Millership, JS | 1 |
| Cao, H; Hille, R; Pauff, JM | 1 |
| Ensafi, AA; Karimi-Maleh, H | 1 |
| Barnaba, C; Choughule, KV; Jones, JP; Joswig-Jones, CA | 1 |
| Dreyer, ZE; Heikamp, E | 1 |
| Krijt, J; Pavelcova, K; Petru, L; Stiburkova, B | 1 |
5 review(s) available for uric acid and mercaptopurine
| Article | Year |
|---|---|
Treatment of acute leukemia.
Topics: Asparaginase; Bacterial Infections; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Hemorrhage; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mitosis; Neoplasms, Nerve Tissue; Prednisone; Remission, Spontaneous; Testicular Neoplasms; Uric Acid; Vincristine | 1972 |
Cancer chemotherapy. 3.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Allopurinol; Alopecia; Antimetabolites; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Drug Synergism; Female; Fetus; Humans; Kidney Calculi; Kidney Diseases; Kidney Tubules; Mechlorethamine; Mercaptopurine; Neoplasms; Pregnancy; Pregnancy Complications; Uric Acid; Vincristine | 1972 |
[Danger of hyperuricemia in the treatment of acute leukemia, lymphosarcoma and reticulosarcoma].
Topics: Acute Disease; Allopurinol; Antineoplastic Agents; Child; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Mercaptopurine; Methotrexate; Prednisone; Uric Acid; Xanthine Oxidase | 1974 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine | 1970 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; Enzyme Precursors; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Leukemia, Myeloid; Liver; Mercaptopurine; Methotrexate; Mice; Molecular Weight; Neoplasms; Nucleic Acids; Proteus; Purines; Research; Species Specificity; Thymine; Transferases; Uric Acid; Xanthine Oxidase | 1969 |
2 trial(s) available for uric acid and mercaptopurine
| Article | Year |
|---|---|
HPLC analysis of azathioprine metabolites in red blood cells, plasma and urine in renal transplant recipients.
Topics: Administration, Oral; Anemia; Antihypertensive Agents; Azathioprine; Drug Interactions; Enalapril; Erythrocytes; Hemoglobins; Humans; Immunosuppressive Agents; Kidney Transplantation; Mercaptopurine; Prospective Studies; Spectrophotometry, Ultraviolet; Uric Acid | 1995 |
Urate oxidase in prevention and treatment of hyperuricemia associated with lymphoid malignancies.
Topics: Allopurinol; Antimetabolites; Antineoplastic Agents; Child; Child, Preschool; Female; Humans; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Urate Oxidase; Uric Acid | 1997 |
46 other study(ies) available for uric acid and mercaptopurine
| Article | Year |
|---|---|
[Basic therapy in children with leukemia and a malignant tumors. II].
Topics: Allopurinol; Anaphylaxis; Anemia; Antibiotics, Antineoplastic; Bicarbonates; Blood Transfusion; Child; Child, Preschool; Cystitis; Disseminated Intravascular Coagulation; Erythrocytes; Female; Furosemide; Heart Arrest; Heparin; Humans; Hydrogen-Ion Concentration; Kidney; Leukemia; Lung Diseases; Male; Mercaptopurine; Mutation; Neoplasms; Phospholipids; Renal Dialysis; Thrombocytopenia; Uric Acid | 1978 |
Oxidizing action of purine N-oxide esters.
Topics: Acetylation; Acetylcysteine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclic N-Oxides; Cysteine; Esters; Guanine; Hydrogen-Ion Concentration; Iodides; Iodine; Mercaptopurine; Methionine; Oxidation-Reduction; Purines; Pyridines; Sulfates; Sulfhydryl Compounds; Tryptophan; Tyrosine; Uric Acid; Xanthines | 1975 |
A spectrophotometric method for the estimation of urinary azathioprine, 6-mercaptopurine, and 6-thiouric acid.
Topics: Animals; Azathioprine; Chemical Precipitation; Chlorides; Chromatography, Ion Exchange; Dogs; Female; Glutathione; Humans; Male; Mercaptopurine; Mercury; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Uric Acid | 1975 |
Plasma concentrations and organ distribution of thiopurines after oral application of azathioprine in mice.
Topics: Administration, Oral; Animals; Azathioprine; Chromatography, High Pressure Liquid; Erythrocytes; Male; Mercaptopurine; Mice; Mice, Inbred Strains; Purines; Thioguanine; Time Factors; Tissue Distribution; Uric Acid | 1991 |
Isolation of 6-mercaptopurine in human plasma by aluminum ion complexation for high-performance liquid chromatographic analysis.
Topics: Aluminum; Cations; Chelating Agents; Chromatography, High Pressure Liquid; Humans; Mercaptopurine; Spectrophotometry, Ultraviolet; Thioguanine; Uric Acid | 1991 |
Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients.
Topics: Administration, Oral; Adult; Azathioprine; Chromatography, High Pressure Liquid; Data Collection; Female; Humans; Kidney Transplantation; Male; Mercaptopurine; Middle Aged; Thioguanine; Time Factors; Uric Acid | 1990 |
Pharmacokinetics of 6-thiouric acid and 6-mercaptopurine in renal allograft recipients after oral administration of azathioprine.
Topics: Adult; Azathioprine; Female; Humans; Kidney Transplantation; Lymphocyte Culture Test, Mixed; Male; Mercaptopurine; Middle Aged; Time Factors; Transplantation, Homologous; Uric Acid | 1989 |
Analysis of 6-mercaptopurine, 6-thioguanine nucleotides, and 6-thiouric acid in biological fluids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Mercaptopurine; Thioguanine; Uric Acid | 1989 |
[Substantiation and effectiveness of the use of purine antagonists in gouty nephropathy].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Gout; Humans; Kidney Diseases; Mercaptopurine; Middle Aged; Time Factors; Uric Acid | 1987 |
Sensitive and specific high-performance liquid chromatographic assay for 6-thiouric acid.
Topics: Animals; Azathioprine; Chromatography, High Pressure Liquid; Indicators and Reagents; Kinetics; Male; Mercaptopurine; Mice; Mice, Inbred C57BL; Thioguanine; Thiouracil; Uric Acid | 1987 |
Increase in uric acid biosynthesis produced by 2-substituted thiadiazoles.
Topics: Azaserine; Azoles; Diazooxonorleucine; Mercaptopurine; Methotrexate; Niacinamide; Nicotinic Acids; Tryptophan; Uric Acid | 1965 |
Monilial septicaemia in acute leukaemia. Successful treatment in a case complicated by acute uric acid nephropathy.
Topics: Acetazolamide; Adolescent; Amphotericin B; Candidiasis; Humans; Infectious Mononucleosis; Kidney Diseases; Leukemia; Male; Mercaptopurine; Methotrexate; Nystatin; Penicillins; Peripheral Nervous System Diseases; Prednisone; Rolitetracycline; Sepsis; Uric Acid | 1966 |
Effect of allopurinol (4-hydroxyprazolo(3,4-d)pyrimidine) on xanthine accumulation by milk xanthine oxidase in vitro.
Topics: Adenine; Allopurinol; Animals; Antimetabolites; Aza Compounds; Azaguanine; Hypoxanthines; In Vitro Techniques; Mercaptopurine; Milk; Oxidoreductases; Purines; Spectrophotometry; Uric Acid; Xanthine Oxidase; Xanthines | 1974 |
Effect of 6-MP and 6-MP-palladium complex on serum uric acid levels in the chick.
Topics: Administration, Oral; Animals; Chickens; Drug Combinations; Mercaptopurine; Palladium; Time Factors; Uric Acid | 1973 |
Cytotoxic drugs in an avian urate microcrystal arthritis.
Topics: Animals; Antineoplastic Agents; Arthritis; Chickens; Columbidae; Cyclophosphamide; Cytarabine; Dactinomycin; Hybridization, Genetic; Inflammation; Male; Mercaptopurine; Nitrosourea Compounds; Procarbazine; Uric Acid; Vinblastine; Vincristine | 1973 |
Gout.
Topics: Allopurinol; Blood Cell Count; Cell Movement; Colchicine; Diet; Drug Synergism; Gastrointestinal Diseases; Gout; Hemorrhage; Humans; Indomethacin; Leukocytes; Mercaptopurine; Phenylbutazone; Probenecid; Purines; Uric Acid | 1974 |
Conversion of azathioprine into mercaptopurine and mercaptoimidazole derivatives in vitro and during immunosuppressive therapy.
Topics: Adult; Azathioprine; Chromatography, Gel; Glutathione; Humans; Imidazoles; In Vitro Techniques; Kidney Transplantation; Male; Mercaptopurine; Spectrophotometry; Sulfhydryl Compounds; Transplantation Immunology; Transplantation, Homologous; Uric Acid | 1967 |
Effect of some drugs on clinical laboratory values as determined by the Technicon SMA 12-60.
Topics: Acetaminophen; Alkaline Phosphatase; Aminosalicylic Acids; Ascorbic Acid; Aspartate Aminotransferases; Autoanalysis; Bilirubin; Blood Chemical Analysis; Blood Glucose; Chemical Phenomena; Chemistry; Cholesterol; Clinical Laboratory Techniques; Dihydroxyphenylalanine; Evaluation Studies as Topic; Humans; Isoniazid; L-Lactate Dehydrogenase; Mercaptopurine; Methyldopa; Pharmaceutical Preparations; Spectrophotometry; Sulfathiazoles; Uric Acid | 1972 |
Azaguanine-resistance as a manifestation of a new form of metabolic overproduction of uric acid.
Topics: Adenine; Adolescent; Aminopterin; Azaguanine; Blood Urea Nitrogen; Carbon Isotopes; Cell Line; Creatinine; Drug Resistance; Electrophoresis, Starch Gel; Erythrocytes; Fibroblasts; Gout; Guanine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Mercaptopurine; Pentosyltransferases; Purines; Uric Acid | 1972 |
Significance of azathioprine metabolites.
Topics: Azathioprine; Binding Sites, Antibody; Carbon Isotopes; Chromatography, Ion Exchange; Humans; Imidazoles; Immune Adherence Reaction; Intestinal Absorption; Liver Diseases; Lymphocytes; Mass Spectrometry; Mercaptopurine; Sulfates; Sulfur Isotopes; Uric Acid | 1972 |
Hyperuricemia complicating leukemia: treatment with allopurinol and dialysis.
Topics: Acetazolamide; Acute Kidney Injury; Adult; Allopurinol; Anuria; Bicarbonates; Blood Gas Analysis; Blood Urea Nitrogen; Carbon Dioxide; Cystoscopy; Electroencephalography; Eye Manifestations; Female; Humans; Leukemia, Lymphoid; Leukocytosis; Mannitol; Mercaptopurine; Methotrexate; Peritoneal Dialysis; Prednisone; Splenomegaly; Thrombocytopenia; Uric Acid; Urinary Catheterization; Vincristine; Water-Electrolyte Balance | 1969 |
Hyperuricemia complicating acute leukemia. Case reports and comments on therapy.
Topics: Adolescent; Allopurinol; Child; Child, Preschool; Female; Humans; Leukemia; Male; Mercaptopurine; Prednisone; Uric Acid; Vincristine | 1970 |
Studies on the photodynamic reaction of purines and purine analogues with methylene blue.
Topics: Anti-Bacterial Agents; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Light; Manometry; Mercaptopurine; Methylene Blue; Nucleosides; Oxygen Consumption; Purines; Spectrophotometry; Theophylline; Uric Acid; Xanthines | 1968 |
Allopurinol and the control of hyperuricemia in neoplastic disease.
Topics: Allopurinol; Humans; Leukemia; Mercaptopurine; Uric Acid | 1968 |
6-thiopurines as substrates and inhibitors of purine oxidases: a pathway for conversion of azathioprine into 6-thiouric acid without release of 6-mercaptopurine.
Topics: Alkanes; Animals; Azathioprine; Cattle; Chemical Phenomena; Chemistry; Glutathione; Humans; Liver; Mercaptopurine; Milk; Oxidoreductases; Rabbits; Uric Acid; Xanthine Oxidase | 1969 |
The management of acute leukemia.
Topics: Adult; Anti-Bacterial Agents; Child; Cyclophosphamide; Hemorrhage; Humans; Infections; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Uric Acid; Vincristine | 1967 |
The use of xanthine oxidase for a specific and sensitive fluorimetric determination of 6-mercaptopurine in serum.
Topics: Chromatography, High Pressure Liquid; Humans; Kinetics; Mercaptopurine; Oxidation-Reduction; Spectrometry, Fluorescence; Uric Acid; Xanthine Oxidase | 1984 |
The absorption of 6-mercaptopurine from 6-mercaptopurine riboside in rat small intestine: effect of phosphate.
Topics: Animals; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Jejunum; Kinetics; Male; Mercaptopurine; Perfusion; Prodrugs; Rats; Rats, Wistar; Regional Blood Flow; Thioinosine; Time Factors; Uric Acid | 1995 |
High performance liquid chromatography analysis of hypoxanthine metabolism in mouse oocyte-cumulus cell complexes: effects of purine metabolic perturbants.
Topics: Adenylosuccinate Synthase; Alanine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Meiosis; Mercaptopurine; Mice; Mycophenolic Acid; Oocytes; Purine-Nucleoside Phosphorylase; Purines; Uric Acid; Xanthine Oxidase | 1994 |
Assessment of exposure to chloramphenicol and azathioprine among workers in a South African pharmaceutical plant.
Topics: Adult; Air Pollutants, Occupational; Azathioprine; Blood Cell Count; Case-Control Studies; Chloramphenicol; Drug Industry; Environmental Monitoring; Humans; Male; Mercaptopurine; Occupational Exposure; South Africa; Uric Acid | 1993 |
Detection and mechanisms of formation of S-(6-purinyl)glutathione and 6-mercaptopurine in rats given 6-chloropurine.
Topics: Animals; Bile; Biliary Tract; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione; Glutathione Transferase; Kidney; Liver; Male; Mercaptopurine; Microsomes; Proteins; Purines; Rats; Rats, Sprague-Dawley; Time Factors; Uric Acid | 1993 |
Ethanol's effect on rat pituitary adrenal axis is prevented by purine metabolic pathway inhibitors.
Topics: Adenosine; Adrenocorticotropic Hormone; Animals; Benzocycloheptenes; Corticosterone; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; In Vitro Techniques; Male; Mercaptopurine; Pituitary-Adrenal System; Purines; Rats; Rats, Wistar; Uric Acid; Xanthine Dehydrogenase | 1999 |
Tumor lysis syndrome in an infant with Langerhans cell histiocytosis successfully treated using continuous arteriovenous hemofiltration.
Topics: Acute Kidney Injury; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Blood Transfusion; Combined Modality Therapy; Disease Progression; Etoposide; Fatal Outcome; Female; Fluid Therapy; Hemofiltration; Histiocytosis, Langerhans-Cell; Humans; Infant; L-Lactate Dehydrogenase; Lymph Nodes; Mercaptopurine; Multiple Organ Failure; Neck; Orbital Diseases; Prednisolone; Sodium Bicarbonate; Temporal Bone; Tumor Lysis Syndrome; Uric Acid; Vinblastine; Vincristine | 2001 |
[Spectrophotometric determination of a mixture of hypoxanthine, xanthine, uric acid & 6-mercaptopurine].
Topics: Humans; Hypoxanthine; Hypoxanthines; Mercaptopurine; Spectrophotometry; Uric Acid; Xanthine; Xanthines | 1957 |
6-Chloropurine and 6-chlorouric acid as substrates and inhibitors of purine-oxidizing enzymes.
Topics: Mercaptopurine; Metabolic Networks and Pathways; Purines; Uric Acid | 1959 |
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA. REPORT OF A CASE TREATED WITH PERITONEAL DIALYSIS.
Topics: Acute Kidney Injury; Adolescent; Blood; Dialysis; Humans; Kidney Diseases; Leukemia; Mercaptopurine; Metabolism; Methotrexate; Peritoneal Dialysis; Renal Dialysis; Renal Insufficiency; Toxicology; Uric Acid; Urine | 1964 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
EFFECT OF PURINES AND SOME OF THEIR ANALOGUES ON PROTEIN AND RNA SYNTHESIS IN ISOLATED NUCLEI.
Topics: Antibody Formation; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Cell Nucleus; Cytosine; Guanine; Leucine; Leukocytes; Lysine; Mercaptopurine; Metabolism; Orotic Acid; Pharmacology; Proteins; Purines; Research; RNA; Thioguanine; Uracil; Uric Acid; Xanthines | 1964 |
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
Topics: Adenine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Kinetics; Mercaptopurine; Models, Chemical; Molecular Structure; Substrate Specificity; Thioguanine; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 2007 |
Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease.
Topics: Adult; Biological Availability; Case-Control Studies; Crohn Disease; Female; Humans; Immunosuppressive Agents; Intestine, Small; Mercaptopurine; Methyltransferases; Uric Acid; Xanthine Oxidase | 2008 |
The development of an objective methodology to measure medication adherence to oral thiopurines in paediatric patients with acute lymphoblastic leukaemia--an exploratory study.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Humans; Male; Medication Adherence; Mercaptopurine; Parents; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Uric Acid | 2009 |
Substrate orientation and catalytic specificity in the action of xanthine oxidase: the sequential hydroxylation of hypoxanthine to uric acid.
Topics: Animals; Biocatalysis; Catalytic Domain; Cattle; Crystallography, X-Ray; Hydroxylation; Hypoxanthine; Kinetics; Mercaptopurine; Models, Molecular; Oxidation-Reduction; Substrate Specificity; Uric Acid; Xanthine Oxidase | 2010 |
Determination of 6-mercaptopurine in the presence of uric acid using modified multiwall carbon nanotubes-TiO2 as a voltammetric sensor.
Topics: Catalysis; Dielectric Spectroscopy; Drug Monitoring; Electrodes; Equipment Design; Humans; Hydrogen-Ion Concentration; Kinetics; Limit of Detection; Linear Models; Mercaptopurine; Microscopy, Electron, Scanning; Nanotubes, Carbon; Oxidation-Reduction; Potentiometry; Surface Properties; Titanium; Uric Acid | 2012 |
In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase.
Topics: Adult; Aged; Aldehyde Oxidase; Cytosol; Escherichia coli; Female; Humans; Liver; Male; Mercaptopurine; Metabolic Detoxication, Phase I; Middle Aged; Recombinant Proteins; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase; Young Adult | 2014 |
50 Years Ago in The Journal of Pediatrics: Prevention and Management of Acute Hyperuricemia in Childhood Leukemia.
Topics: Acute Disease; Allopurinol; Child; DNA, Neoplasm; History, 20th Century; Humans; Hyperuricemia; Mercaptopurine; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Lysis Syndrome; Uric Acid | 2017 |
Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II).
Topics: Adult; Aldehyde Oxidase; Female; Humans; Mercaptopurine; Methyltransferases; Polymorphism, Genetic; Purine-Pyrimidine Metabolism, Inborn Errors; Sulfurtransferases; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 2018 |