uric acid and isoxazoles

uric acid has been researched along with isoxazoles in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dan, T; Koga, H; Onuma, E; Tanaka, H1
Dan, T; Koga, H1
Dan, T; Koga, H; Tanaka, H1
Aoki, B; Dan, T; Koga, H; Onuma, E; Sato, H; Tanaka, H1
Dan, T; Onoma, M; Onuma, E; Ozawa, K; Yoneya, T1
Joo, HJ; Kim, KA; Park, JY1
Dhaun, N; Goddard, J; Johnston, NR; Webb, DJ1
Arida, D; Silva, L; Skare, TL1
Benza, RL; Dhaun, N; Hwang, LJ; Liu, X; Naeije, R; Teal, S; Vachiery, JL; Webb, DJ1
Choe, JY; Kim, SK1
Cai, GY; Chen, XM; Duan, SW; Huang, W; Jia, Q; Li, JJ; Li, WG; Li, XM; Liu, SW; Liu, WH; Lun, LD; Ma, L; Sun, XF; Wang, YP; Wu, H; Wu, J; Xie, YS; Zhang, JR; Zhou, CH1
Alfieri, DF; Costa, NT; de Medeiros, FA; de Sá, MC; Dichi, I; Iriyoda, TMV; Lozovoy, MAB; Maes, M; Micheletti, PL; Reiche, EMV; Scavuzzi, BM; Sekiguchi, BA; Simão, ANC1

Trials

3 trial(s) available for uric acid and isoxazoles

ArticleYear
Chronic selective endothelin A receptor antagonism reduces serum uric acid in hypertensive chronic kidney disease.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:2

    Topics: Cross-Over Studies; Double-Blind Method; Endothelin A Receptor Antagonists; Hypertension; Hyperuricemia; Isoxazoles; Kidney Failure, Chronic; Thiophenes; Treatment Outcome; Uric Acid

2011
Endothelin antagonism and uric acid levels in pulmonary arterial hypertension: clinical associations.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2014, Volume: 33, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Bosentan; Child; Dose-Response Relationship, Drug; Double-Blind Method; Endothelin Receptor Antagonists; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Isoxazoles; Male; Middle Aged; Prospective Studies; Sulfonamides; Survival Rate; Thiophenes; Time Factors; Treatment Outcome; United States; Uric Acid; Young Adult

2014
Efficacy of Leflunomide, Telmisartan, and Clopidogrel for Immunoglobulin A Nephropathy: A Randomized Controlled Trial.
    Chinese medical journal, 2016, Aug-20, Volume: 129, Issue:16

    Topics: Adolescent; Adult; Benzimidazoles; Benzoates; Blood Pressure; China; Clopidogrel; Creatinine; Female; Glomerular Filtration Rate; Glomerulonephritis, IGA; Humans; Isoxazoles; Kidney Function Tests; Leflunomide; Male; Middle Aged; Prospective Studies; Telmisartan; Ticlopidine; Treatment Outcome; Uric Acid; Young Adult

2016

Other Studies

9 other study(ies) available for uric acid and isoxazoles

ArticleYear
A selective uricosuric action of AA-193 in rats. Comparison with its effect on PAH secretion in vivo and in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:5

    Topics: Animals; In Vitro Techniques; Isoxazoles; Kidney; Male; Microvilli; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Renal Circulation; Ticrynafen; Uric Acid; Uricosuric Agents

1991
Uricosurics inhibit urate transporter in rat renal brush border membrane vesicles.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Hydroxides; In Vitro Techniques; Intracellular Membranes; Ion Exchange; Isoxazoles; Kidney; Kinetics; Male; Microvilli; Rats; Rats, Inbred Strains; Uric Acid; Uricosuric Agents

1990
Mechanism of uricosuric action of AA-193 in DBA/2N mice.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: Animals; Inulin; Isoxazoles; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Oxazoles; Pyrazinamide; Species Specificity; Uric Acid; Uricosuric Agents

1990
The activity of AA-193, a new uricosuric agent, in animals.
    Advances in experimental medicine and biology, 1989, Volume: 253A

    Topics: Animals; Cebus; Dose-Response Relationship, Drug; Gout Suppressants; Isoxazoles; Male; Metabolic Clearance Rate; Mice; Pyrazinamide; Rats; Rats, Inbred Strains; Species Specificity; Uric Acid; Uricosuric Agents; Urinary Bladder

1989
Hypouricemic and uricosuric actions of AA-193 in a hyperuricemic rat model.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:1

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Isoxazoles; Kidney; Liver; Male; Oxonic Acid; Rats; Rats, Wistar; Time Factors; Urate Oxidase; Uric Acid; Uricosuric Agents; Xanthine Dehydrogenase

1994
Effect of ABCG2 genotypes on the pharmacokinetics of A771726, an active metabolite of prodrug leflunomide, and association of A771726 exposure with serum uric acid level.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:2

    Topics: Aniline Compounds; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Crotonates; Genotype; Humans; Hydroxybutyrates; Isoxazoles; Leflunomide; Neoplasm Proteins; Nitriles; Polymorphism, Single Nucleotide; Prodrugs; Protein Transport; Toluidines; Uric Acid

2011
The hypouricemiant effect of leflunomide.
    Joint bone spine, 2014, Volume: 81, Issue:3

    Topics: Adult; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Uric Acid

2014
Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomide.
    Clinica chimica acta; international journal of clinical chemistry, 2015, Jan-01, Volume: 438

    Topics: Aged; Arthritis, Rheumatoid; Female; Glomerular Filtration Rate; Humans; Inflammation; Isoxazoles; Leflunomide; Male; Middle Aged; Uric Acid

2015
Metabolic syndrome and the decreased levels of uric acid by leflunomide favor redox imbalance in patients with rheumatoid arthritis.
    Clinical and experimental medicine, 2018, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Advanced Oxidation Protein Products; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Case-Control Studies; Disease Progression; Female; Gene Expression; Humans; Isoxazoles; Leflunomide; Lipid Peroxides; Male; Metabolic Syndrome; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Sex Factors; Uric Acid

2018