uric acid and inosine

uric acid has been researched along with inosine in 152 studies

Research

Studies (152)

TimeframeStudies, this research(%)All Research%
pre-199065 (42.76)18.7374
1990's29 (19.08)18.2507
2000's26 (17.11)29.6817
2010's19 (12.50)24.3611
2020's13 (8.55)2.80

Authors

AuthorsStudies
Magill, CW; Magill, JM; Sabina, RL1
Hanks, AR; Magill, CW; Magill, JM; Sabina, RL1
Buhl, L; Buhl, MR1
Ballieux, RE; de Bree, PK; Hendrickx, GF; Staal, GE; Stoop, JW; van Heukelom, LH; Wadman, SK; Zegers, BJ1
Biggar, D; Edwards, NL; Fox, IH; Gelfand, EW1
Edwards, NL; Fox, IH; Recker, D1
Hashimoto, M; Matsunaga, Y; Miyazaki, H1
Ammann, AJ; Cohen, A; Doyle, D; Martin, DW1
Schatz, RA; Sellinger, OZ; Vunnam, CR1
Haeckel, R1
Karasawa, Y1
Badenoch-Jones, P; Buttery, PJ1
Saugstad, OD1
Glew, RH; Ihler, G; Lantzy, A; Purpura, J1
Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S1
Elsayed, NM; Ferraris, SP; Lew, H1
García Neito, V; García Puig, J; López Jiménez, M; Mateos Antón, F; Ramos Hernández, T; Sebastián Melián, J1
Gardiner, EE; Keng, JY; Newberry, RC1
Hada, T; Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T; Yokoyama, H1
Eklof, B; Jabs, CM; Neglen, P; Thomas, EJ1
Becker, MA; Jiménez, ML; Mateos, FA; Melián, JS; Nieto, VG; Puig, JG; Ramos, TH1
Barraco, RA; Phillis, JW; Polasek, PM; Thorderson, J; Walter, GA1
Castroviejo, IP; Jiménez, ML; Mateos, FA; Puig, JG; Ramos, TH; Vázquez, JO1
Hara, N; Kawachi, M; Kiyokawa, H; Kono, N; Kuwajima, M; Mineo, I; Nakajima, H; Shimizu, T; Wang, YL; Yamada, Y1
O'Reagan, MH; Phillis, JW; Walter, GA1
Hara, N; Kono, N; Mineo, I; Nonaka, K; Shimizu, T; Tarui, S; Yamada, Y1
McCaman, MW1
Iigo, M; Ishitsuka, H; Miwa, M; Nitta, K1
Wheeler, CP; Yudilevich, DL1
O'Regan, MH; Phillis, JW; Walter, GA1
Gavin, JB; Humphrey, SM; Vanderwee, MA1
Dorigo, P; Gaion, RM; Gambarotto, L1
Hara, N; Kawachi, M; Kiyokawa, H; Kono, N; Mineo, I; Shimizu, T; Tarui, S; Wang, YL; Yamada, Y1
Edlund, A; Fitzgerald, GA; Nowak, J; Wennmalm, A; Wennmalm, M1
Al-Jurf, AS; Berlinger, WG; Spector, R; Stene, RA1
Kather, H; Waas, W; Wieland, E1
Kamatani, N; Kitamura, M; Kojima, T; Nishina, T; Nishioka, K1
Hadano, S; Ito, A; Ogasawara, M1
Achterberg, PW; De Jong, JW; Stroeve, RJ1
Pimenov, AM; Prokudin, VIu; Sitnikov, VF; Tikhonov, IuV; Toguzov, RT1
Hashimoto, T; Hayakawa, T; Ikeda, T; Jamshidi, J; Masana, Y; Mogami, H; Morimoto, K1
Hara, N; Kono, N; Mineo, I; Nonaka, K; Shimizu, T; Sumi, S; Tarui, S; Yamada, Y1
Kim, HD; Metzler, MH; Moran, JB; Zeidler, RB1
Dale, DC; Hammond, WP; Osborne, WR1
Feldheim, W; Gazo, M1
Flouret, G; Hechter, O1
Matsuda, Y1
Barratt, E; Boorman, KN; Buttery, PJ1
Caen, JP; Jenkins, CS; Pokutecky, J; Vainer, H1
Field, J; March, J; Shanley, J; Turner, WJ1
Delivoria-Papadopoulos, M; Miller, LD; Oski, FA; Pollock, TW; Rosato, EF; Sugerman, HJ1
Karasawa, Y; Shibata, F; Tasaki, I; Yokota, HO1
Caen, JP; Chivot, JJ; Jenkins, CS; Levy-Toledano, S; Michel, H; Rendu, F1
Camakaris, J; Cotton, RG; Danks, DM1
Balinsky, JB1
Buka, MR; Zhagat, RA; Zvirgzda, IK1
Achterberg, PW; de Jong, JW; de Tombe, PP; Harmsen, E1
Fredholm, BB; Lerner, U1
Brown, PR; Nicol, SC; Perrone, P; Sallis, JD1
Holliss, DG; Humphrey, SM; Seelye, RN1
Fredholm, B; Hohlbach, G; Schildberg, FW; Schoenberg, M1
García Puig, J; Gaspar, G; Martínez, ME; Mateos Antón, F; Muñoz Sanz, A; Ortiz Vázquez, J; Posada, I; Ramos, T1
Harkness, RA; Lund, RJ1
De Jong, JW; De Tombe, PP; Harmsen, E1
Chagoya de Sánchez, V; Díaz-Muñoz, M; Glender, W; Hernández-Muñoz, R; Suárez, J; Vidrio, S; Villalobos, R; Yañez, L1
Fawaz, E; Fawaz, G; Manoukian, E; Simaan, J1
Harkness, RA; Hytten, FE; O'Connor, MC; Simmonds, RJ1
Briske-Anderson, M; Duerre, JA1
Calvert, AH; Dady, PJ; Harrap, KR; Muindi, JF; Smith, IE; Smyth, JF; Taylor, GA1
Assenza, SP; Brown, PR1
Fox, IH; Sutton, JR; Toews, CJ; Ward, GR1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
Bory, C; Boulieu, R; Chantin, C1
Higashino, K; Hiroishi, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Yamakita, J; Yamamoto, T1
Hamby, RL; Henderson, GI; Perez, AB; Schenken, RS; Schenker, S; Yang, Y1
Eklund, T; Hillered, L; Wahlberg, J1
Lautt, WW; Li, T; Zhang, YL1
Downs, SM1
Balsom, PD; Hellsten-Westing, Y; Norman, B; Sjödin, B1
Ekblom, B; Hellsten-Westing, Y; Kaijser, L; Sjödin, B1
Abe, T; Hisatome, I; Kato, T; Kosaka, H; Mitani, Y; Miyakoda, H; Ogino, K; Takami, T; Tanaka, Y; Yoshida, A1
Aalto, TK; Raivio, KO1
Grauel, EL; Grune, T; Schmidt, H; Siems, WG1
Gross, GJ; Mei, DA; Nithipatikom, K1
Aguilar-Roblero, R; Chagoya de Sánchez, V; Díaz-Muñoz, M; Drucker-Colín, R; Fernández-Cancino, F; Hernández-Muñoz, R; Oksenberg, A; Rosenthal, L; Suárez, J; Vega-González, A; Vidrio, S; Villalobos, L; Yáñez, L1
Higashino, K; Moriwaki, Y1
Barclay, KD; Buckley, SJ; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK1
Delivoria-Papadopoulos, M; Marro, P; Pastuszko, P; Wilson, DF1
Jayakumar, J; Seymour, AM; Smolenski, RT; Yacoub, MH1
Makarewicz, W; Smolenski, RT; Yacoub, MH; Zych, M1
Gross, GJ; Lasley, RD; Mei, DA; Nithipatikom, K1
Bargossi, AM; Bianchi, GP; Fiorella, PL; Grossi, G; Marchesini, G1
Carey, MF; Snow, RJ; Stathis, CG; Zhao, S1
Dalton, B; McNaughton, L; Tarr, J1
Feng, JD; Yeung, PK1
Klejewski, A; Szcześniak-Chmielecka, A; Urbaniak, T; Zeromska-Cancellaro, M1
Delogu, MR; Desole, MS; Esposito, G; Fresu, L; Miele, M; Migheli, R; Rocchitta, G; Serra, PA1
Al-Awadi, FM; Khan, I1
Hooper, DC; Koprowskil, H; Leist, T; Mikheeva, T; Spitsin, S; Streletz, LJ1
Klandorf, H; Simoyi, MF; Van Dyke, K1
Cheng, J; Hada, T; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T1
Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV1
Blemings, KP; Falkenstein, E; Klandorf, H; Simoyi, MF; Van Dyke, K1
Davydova, SA; Gourine, AV; Hanafy, N; Hu, Q; Kuzmin, AI; Sander, PR; Zaretsky, DV; Zhang, J1
Greeve, I; Lienert, C; Mattle, HP1
Barsky, L; Buckley, S; Warburton, D; Weinberg, K1
Carey, MF; Snow, RJ; Stathis, CG1
Kitagawa, J; Mikami, T1
Toncev, G1
Carey, MF; Garnham, AP; Hayes, A; Snow, RJ; Stathis, CG1
Hatzigeorgiou, AG; Iizasa, H; Kawahara, Y; Nishikura, K; Sethupathy, P; Zinshteyn, B1
Chintala, S; Gobe, GG; Goligorsky, MS; Patschan, D; Patschan, S1
Ciechanowski, K; Domanski, L; Dutkiewicz, G; Jakubowska, K; Myslak, M; Ostrowski, M; Pawlik, A; Rozanski, J; Safranow, K1
Bracht, A; Bracht, F; Broetto-Biazon, AC; Constantin, J; de Sá-Nakanishi, AB; Kelmer-Bracht, AM; Lopez, CH1
Koprowski, H; Spitsin, S1
Casotti, G; Falkenstein, E; Klandorf, H; Moritz, J; Seaman, C; Van Dyke, K1
Hu, P; Li, P; Liang, QL; Luo, GA; Wang, YM; Xia, JF1
Bracht, A; Bracht, F; Bracht, L; Broetto-Biazon, AC; Kelmer-Bracht, AM1
Hooper, DC; Jacobs, D; Koprowski, H; Markowitz, CE; Spitsin, S; Udupa, JK; Zimmerman, V1
Whitmarsh, TE1
Hooper, DC; Koprowski, H; Markowitz, CE; Spitsin, S; Zimmerman, V1
D'hooghe, MB; De Deyn, PP; Gonsette, RE; Guillaume, D; Medaer, R; Michotte, A; Seeldrayers, P; Sindic, C1
Dolegowska, B; Dudzinska, W; Lubkowska, A; Safranow, K1
John, SA; Revin, SB1
Hiratochi, M; Isaji, M; Itoh, F; Kamada, N; Kikuchi, N; Kuramochi, Y; Shimizu, K; Tatani, K1
Carro, MD; Falkenstein, E; Klandorf, H; Radke, W; Settle, T1
Burdett, T; Desjardins, CA; Frosch, MP; McFarland, NR; Schwarzschild, MA1
Bazin, D; Da Costa, A; Daudon, M; Dessombz, A; Laverriere-Loss, A; Metref, S; Moret, C; Preitner, F; Rotman, S; Sandt, C; Thorens, B1
Ahmed, A; Ainslie, M; Antonelle de Marcaida, J; Ascherio, A; Barles, G; Beal, MF; Brocht, AF; Bwala, G; Carter, JH; Carvajal, L; Castillo, R; Constantinescu, R; Cook, M; Cotto, C; Cudkowicz, ME; Curhan, GC; Eaton, K; Ede, P; Encarnacion, E; Espay, AJ; Friedman, JH; Gartner, M; Gauger, L; Goetz, CG; Goudreau, JL; Grasso, DL; Hare, JM; Hooper, DC; Hope-Porche, C; Hung, A; Isaacson, SH; Jaglin, J; James, R; Johnson, J; Kieburtz, KD; Lenehan, R; Logan, R; Macklin, EA; McClurg, L; Murray, M; Niles, L; Oakes, D; Orme, C; Parashos, SA; Rao, J; Ross, T; Rudolph, A; Russell, D; Russell, DS; Saint-Hilaire, MH; Schwarzschild, MA; Sharma, S; Shoulson, I; Stacy, MA; Tennis, MK; Thomas, CA; Thurlow, S; Togasaki, D; Venuto, C; Weber, J1
Bakshi, R; Cipriani, S; Schwarzschild, MA1
Aragon-Martinez, OH; Galicia, O; Isiordia-Espinoza, MA; Martinez-Morales, F1
Li, M; Mei, L; Xie, A; Yang, D; Yuan, J; Yuan, L1
Iseki, K; Kaneko, C; Kobayashi, M; Koizumi, T; Kuwayama, K; Ogura, J; Sasaki, S; Takaya, A; Takeno, R; Tsujimoto, T; Yabe, K; Yamaguchi, H1
Ashizawa, N; Iwanaga, T; Matsumoto, K; Saitoh, K; Taniguchi, T1
Ascherio, A; Bakshi, R; Bhattacharyya, S; Logan, R; Macklin, EA; Schwarzschild, MA1
Cao, L; Hu, P; Jiang, M; Liu, J; Ruan, S; Sun, W; Xu, Y; Zhang, H; Zhang, M1
Ando, R; Iwaki, H; Miyaue, N; Nagai, M; Nishikawa, N; Nomoto, M; Tada, S; Tsujii, T; Yabe, H1
Fukuuchi, T; Iyama, N; Kaneko, K; Yamaoka, N1
Goyal, RN; Moon, JM; Park, DS; Raj, M; Shim, YB1
Banno, Y; Fujii, T; Kakino, K; Kusakabe, T; Lee, JM; Tanaka, M1
Hu, P; Jiang, M; Jin, Y; Kang, L; Liu, J; Zhang, H; Zhang, M1
Dalbeth, N; Gamble, GD; Horne, A; Merriman, TR; Mihov, B; Reid, IR; Stamp, LK; Stewart, A1
Huang, X; Li, ZL; Ma, KL; Tang, DH; Wang, CY; Ye, YS; Yi, HK; Zhang, JW1
Ahmed, A; Ainslie, M; Aldred, J; Ascherio, A; Beck, CA; Bhatti, D; Bixby, M; Blindauer, K; Bodis-Wollner, I; Bolger, P; Boyd, JT; Brodsky, M; Bwala, G; Callahan, KF; Casaceli, C; Chou, K; Christine, C; Ciccarello, J; Cloud, L; Criswell, SR; Crotty, GF; Curhan, GC; Daley, A; de Marcaida, JA; Deik, AF; Dewey, RB; Durphy, J; Espay, AJ; Fang, JY; Fitzgerald, R; Friedman, JH; Gauger, L; Gerald, A; Goetz, C; Goudreau, J; Gunzler, SA; Hauser, RA; Henchcliffe, C; Hinson, V; Houghton, DJ; Houston, E; Hung, A; Hunter, C; James, R; Jimenez-Shahed, J; Kaminski, P; Kamp, C; Keith, K; Klements, D; Kostrzebski, M; Kumar, R; Kurlan, R; LaFaver, K; Lang, A; Langhammer, A; Laroche, A; LeDoux, MS; Leehey, M; LeWitt, PA; Litvan, I; Lungu, C; Macklin, EA; Marek, K; Mari, Z; McGraw, M; McMahon, GM; Mehta, SH; Mestre, T; Morgan, JC; Mosovsky, S; Mozaffarian, D; Oakes, D; Pahwa, R; Park, A; Peterson, C; Poon, C; Pothier, L; Rabin, M; Ratel, AS; Reich, S; Rosenthal, L; Rudolph, A; Russell, D; Saint-Hilaire, M; Schiess, MC; Schneider, RB; Schwarzschild, MA; Scott, B; Serrano, C; Shah, BB; Shill, HA; Shoulson, I; Shprecher, D; Simon, DK; Simuni, T; Soileau, M; Stover, N; Suski, V; Thomas, K; Videnovic, A; Waikar, SS; Waters, C; Zauber, SE; Zhang, L1
Aponte, A; Cockman, ME; Gucek, M; Harris, M; Keeran, K; Kennedy, LM; Murphy, E; Pirooznia, M; Singh, K; Springer, D; Sun, J1
Ascherio, A; Macklin, EA; Schwarzschild, MA1
Frucht, SJ1
Baciu, C; Cypel, M; Hsin, M; Keshavjee, S; Liu, M; Shin, J1
Chan, J; Goetz, CG; Luo, S; Macklin, EA; Oakes, D; Schwarzschild, MA; Simuni, T; Stebbins, GT; Zou, H1
Basile, MS; Bramanti, P; Mazzon, E1
Dalbeth, N; Gamble, GD; Horne, A; Merriman, TR; Mihov, B; Mount, D; Reid, IR; Stamp, LK; Stewart, A1
Berry, JD; Beukenhorst, AL; Chan, J; Chase, M; Connolly, M; Cudkowicz, ME; Dagostino, D; Ferment, V; Gelevski, D; Hall, M; Lieberman, C; Locatelli, E; Macklin, EA; Manousakis, G; Nicholson, K; Onnela, JP; Ostrow, J; Paganoni, S; Pothier, L; Randall, R; Schwarzschild, MA; Sherman, AV; Steinhart, E; Walk, D; Walker, DG; Walker, J; Wills, AM; Yu, H1

Reviews

6 review(s) available for uric acid and inosine

ArticleYear
[Regulation of synthesis of uric acid as the final stage of nitrogen metabolism].
    Saishin igaku. Modern medicine, 1972, Volume: 27, Issue:4

    Topics: Animals; Chickens; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Glycine; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Liver; Nitrogen; Nucleotidases; Phosphorylase Kinase; Rats; Serine; Uremia; Uric Acid; Xanthine Oxidase; Xanthines

1972
[Methods of determining adenosine deaminase (review of the literature)].
    Laboratornoe delo, 1982, Issue:6

    Topics: Adenosine Deaminase; Ammonia; Catalysis; Chromatography, Ion Exchange; Chromatography, Liquid; Chromatography, Thin Layer; Erythrocytes; Hypoxanthine; Hypoxanthines; Inosine; Lymphocytes; Methods; Nucleoside Deaminases; Radioimmunoassay; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Uric Acid; Xanthine; Xanthines

1982
[Pharmacological agents affecting uric acid metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:12

    Topics: Allopurinol; Diuretics; Fructose; Gout; Gout Suppressants; Humans; Inosine; Kidney Diseases; Niacin; Purines; Uric Acid; Xylitol

1996
[Uric acid and multiple sclerosis].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:9

    Topics: Biomarkers; Free Radical Scavengers; Humans; Inosine; Multiple Sclerosis; Reference Values; Uric Acid

2004
Role of uric acid in multiple sclerosis.
    Current topics in microbiology and immunology, 2008, Volume: 318

    Topics: Blood-Brain Barrier; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Female; Free Radicals; Humans; Inosine; Male; Multiple Sclerosis; Treatment Outcome; Uric Acid

2008
Inosine in Neurodegenerative Diseases: From the Bench to the Bedside.
    Molecules (Basel, Switzerland), 2022, Jul-21, Volume: 27, Issue:14

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Humans; Inosine; Multiple Sclerosis; Neurodegenerative Diseases; Parkinson Disease; Quality of Life; Uric Acid

2022

Trials

17 trial(s) available for uric acid and inosine

ArticleYear
Vascular effects of infused adenosine are not mediated by prostacyclin release in humans.
    The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adult; Epinephrine; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Heart Rate; Hemodynamics; Humans; Hypoxanthine; Hypoxanthines; Inosine; Leg; Male; Regional Blood Flow; Uric Acid

1987
Biochemical observations during a trial of inosiplex in senile dementia.
    Journal of the American Geriatrics Society, 1973, Volume: 21, Issue:8

    Topics: Aged; Amino Alcohols; Benzoates; Body Weight; Clinical Trials as Topic; Dementia; Humans; Hypoxanthines; Inosine; Male; Purinones; Time Factors; Uric Acid; Xanthines

1973
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol

1995
Inosine supplementation has no effect on aerobic or anaerobic cycling performance.
    International journal of sport nutrition, 1999, Volume: 9, Issue:4

    Topics: 2,3-Diphosphoglycerate; Analysis of Variance; Bicycling; Dietary Supplements; Double-Blind Method; Exercise; Humans; Inosine; Male; Uric Acid

1999
Inactivation of peroxynitrite in multiple sclerosis patients after oral administration of inosine may suggest possible approaches to therapy of the disease.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2001, Volume: 7, Issue:5

    Topics: Administration, Oral; Adult; Female; Gadolinium; Humans; Inosine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Peroxynitrous Acid; Uric Acid

2001
The influence of allopurinol on urinary purine loss after repeated sprint exercise in man.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:10

    Topics: Adult; Allopurinol; Exercise; Humans; Inosine; Kidney; Male; Purines; Uric Acid

2005
Therapeutic value of serum uric acid levels increasing in the treatment of multiple sclerosis.
    Vojnosanitetski pregled, 2006, Volume: 63, Issue:10

    Topics: Administration, Oral; Adolescent; Adult; Female; Humans; Inosine; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Uric Acid

2006
The treatment of multiple sclerosis with inosine.
    Journal of alternative and complementary medicine (New York, N.Y.), 2009, Volume: 15, Issue:6

    Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Brain; CD4 Lymphocyte Count; Central Nervous System; Cross-Over Studies; Cytokines; Disability Evaluation; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Inosine; Kidney Calculi; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Th1 Cells; Th2 Cells; Tyrosine; Uric Acid; Young Adult

2009
Modulation of serum uric acid levels by inosine in patients with multiple sclerosis does not affect blood pressure.
    Journal of human hypertension, 2010, Volume: 24, Issue:5

    Topics: Administration, Oral; Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Humans; Inosine; Male; Middle Aged; Multiple Sclerosis; Treatment Outcome; Uric Acid

2010
Boosting endogenous neuroprotection in multiple sclerosis: the ASsociation of Inosine and Interferon beta in relapsing- remitting Multiple Sclerosis (ASIIMS) trial.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2010, Volume: 16, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Belgium; Disability Evaluation; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inosine; Interferon beta-1a; Interferon beta-1b; Interferon-beta; Kaplan-Meier Estimate; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neuroprotective Agents; Severity of Illness Index; Time Factors; Treatment Outcome; Uric Acid

2010
The effects of allopurinol, uric acid, and inosine administration on xanthine oxidoreductase activity and uric acid concentrations in broilers.
    Poultry science, 2012, Volume: 91, Issue:11

    Topics: Allopurinol; Animals; Chickens; Enzyme Inhibitors; Female; Inosine; Male; Uric Acid; Xanthine Oxidase

2012
Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial.
    JAMA neurology, 2014, Volume: 71, Issue:2

    Topics: Aged; Biomarkers; Double-Blind Method; Female; Follow-Up Studies; Humans; Inosine; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Uric Acid

2014
One year safety and efficacy of inosine to increase the serum urate level for patients with Parkinson's disease in Japan.
    Journal of the neurological sciences, 2017, Dec-15, Volume: 383

    Topics: Administration, Oral; Aged; Antiparkinson Agents; Dose-Response Relationship, Drug; Female; Humans; Inosine; Japan; Male; Parkinson Disease; Treatment Outcome; Uric Acid

2017
Elevated Urate Levels Do Not Alter Bone Turnover Markers: Randomized Controlled Trial of Inosine Supplementation in Postmenopausal Women.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:9

    Topics: Absorptiometry, Photon; Aged; Bone Density; Bone Remodeling; Collagen Type I; Double-Blind Method; Female; Humans; Hyperuricemia; Inosine; Peptides; Phosphopeptides; Postmenopause; Procollagen; Uric Acid

2021
Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial.
    JAMA, 2021, 09-14, Volume: 326, Issue:10

    Topics: Aged; Biomarkers; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Female; Humans; Inosine; Kidney Calculi; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Treatment Failure; Uric Acid

2021
Effects of elevated serum urate on cardiometabolic and kidney function markers in a randomised clinical trial of inosine supplementation.
    Scientific reports, 2022, 07-28, Volume: 12, Issue:1

    Topics: Biomarkers; Cardiovascular Diseases; Creatinine; Dietary Supplements; Double-Blind Method; Female; Glucose; Humans; Inosine; Kidney; Lipids; Uric Acid

2022
Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis.
    Muscle & nerve, 2023, Volume: 67, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Double-Blind Method; Humans; Inosine; Retrospective Studies; Uric Acid

2023

Other Studies

129 other study(ies) available for uric acid and inosine

ArticleYear
Regulation of hypoxanthine transport in Neurospora crassa.
    Journal of bacteriology, 1976, Volume: 128, Issue:2

    Topics: Biological Transport, Active; Genes; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Inosine Nucleotides; Mutation; Neurospora; Neurospora crassa; Spectrophotometry, Ultraviolet; Uric Acid

1976
Role of purine base excretion in regulation of purine pools.
    Molecular & general genetics : MGG, 1979, May-23, Volume: 173, Issue:1

    Topics: Adenine; Hypoxanthines; Inosine; Neurospora; Neurospora crassa; Purines; Uric Acid; Xanthines

1979
Urid acid accumulated in isolated kidney grafts: an assessment of agonal ischaemia.
    International urology and nephrology, 1979, Volume: 11, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthines; In Vitro Techniques; Inosine; Ischemia; Kidney; Kidney Transplantation; Lactates; Male; Organ Preservation; Rabbits; Uric Acid; Xanthines

1979
Purine nucleoside phosphorylase deficiency associated with selective cellular immunodeficiency.
    The New England journal of medicine, 1977, Mar-24, Volume: 296, Issue:12

    Topics: B-Lymphocytes; Electrophoresis; Female; Humans; Immunoelectrophoresis; Immunologic Deficiency Syndromes; Infant; Inosine; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; T-Lymphocytes; Uric Acid

1977
Partial deficiency of purine nucleoside phosphorylase: studies of purine and pyrimidine metabolism.
    The Journal of laboratory and clinical medicine, 1978, Volume: 91, Issue:5

    Topics: Adenosine Deaminase; Child; Erythrocytes; Guanosine; Humans; Immunologic Deficiency Syndromes; Inosine; Male; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; T-Lymphocytes; Uric Acid

1978
Overproduction of uric acid in hypoxanthine-guanine phosphoribosyltransferase deficiency. Contribution by impaired purine salvage.
    The Journal of clinical investigation, 1979, Volume: 63, Issue:5

    Topics: Adenine; Adolescent; Adult; Aged; Carbon Radioisotopes; Child; Child, Preschool; Fructose; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Middle Aged; Purines; Uric Acid

1979
Distribution of [14C]labeled purines in the mouse. A whole body autoradiographic assessment of purine metabolism in mammals.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1978, Volume: 26, Issue:8

    Topics: Adenosine; Animals; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Erythrocytes; Hypoxanthines; Inosine; Male; Mice; Organ Specificity; Purines; Thymidine; Uric Acid; Uridine; Xanthines

1978
Abnormal purine metabolism and purine overproduction in a patient deficient in purine nucleoside phosphorylase.
    The New England journal of medicine, 1976, Dec-23, Volume: 295, Issue:26

    Topics: Child; Erythrocytes; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Immunologic Deficiency Syndromes; Inosine; Lesch-Nyhan Syndrome; Male; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Purine Nucleotides; Purine-Nucleoside Phosphorylase; Purines; Uric Acid

1976
Species and tissue differences in the catabolism of S-adenosyl-L-homocysteine: a quantitative, chromatographic study.
    Life sciences, 1977, Jan-15, Volume: 20, Issue:2

    Topics: Adenine; Animals; Brain; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; Hypoxanthines; Inosine; Kidney; Liver; Male; Mice; Rats; S-Adenosylhomocysteine; Species Specificity; Uric Acid; Xanthines

1977
Hepatic gluconeogenesis and urate formation from various nucleosides.
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: Allantoin; Animals; Fasting; Gluconeogenesis; Hexosephosphates; Inosine; Kinetics; Liver; Liver Glycogen; Perfusion; Purine Nucleosides; Purine Nucleotides; Purines; Rats; Ribose; Trioses; Uric Acid; Xanthines

1977
Stimulatory effect of intraportal ammonia on plasma uric acid concentration and urinary uric acid excretion in chickens fed a low protein diet.
    The Journal of nutrition, 1977, Volume: 107, Issue:7

    Topics: Ammonia; Animals; Asparagine; Chickens; Glutamine; Inosine; Liver; Male; Protein Deficiency; Quaternary Ammonium Compounds; Uric Acid

1977
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.
    The Biochemical journal, 1976, Sep-15, Volume: 158, Issue:3

    Topics: Adenine; Adenosine Monophosphate; Animals; Chickens; Formates; Glycine; Guanine; Guanine Nucleotides; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Liver; Lymphoid Tissue; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical; Uric Acid

1976
Hypoxanthine as a measurement of hypoxia.
    Pediatric research, 1975, Volume: 9, Issue:4

    Topics: Apgar Score; Fetus; Humans; Hypoxanthines; Hypoxia; Infant, Newborn; Inosine; Respiratory Distress Syndrome, Newborn; Uric Acid

1975
Enzymatic degradation of uric acid by uricase-loaded human erythrocytes.
    The Journal of clinical investigation, 1975, Volume: 56, Issue:3

    Topics: Biological Transport; Erythrocytes; Glycolysis; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Intracellular Fluid; Kinetics; Lactates; Sodium; Time Factors; Urate Oxidase; Uric Acid

1975
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
    Developmental medicine and child neurology, 1991, Volume: 33, Issue:10

    Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines

1991
Simultaneous determination of inosine, hypoxanthine, xanthine, and uric acid and the effect of metal chelators.
    Analytical biochemistry, 1991, May-15, Volume: 195, Issue:1

    Topics: Adenosine Triphosphate; Animals; Chelating Agents; Chromatography; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lung; Male; Perfusion; Purinones; Rats; Rats, Inbred Strains; Reproducibility of Results; Sensitivity and Specificity; Time Factors; Uric Acid; Xanthine; Xanthines

1991
[Metabolism of purine nucleotides in the central nervous system in patients with phosphoribosylpyrophosphate synthetase hyperactivity and neurosensory deafness].
    Neurologia (Barcelona, Spain), 1990, Volume: 5, Issue:1

    Topics: Adult; Brain; Child; Deafness; Female; Genetic Carrier Screening; Gout; Homozygote; Humans; Hypoxanthines; Inosine; Male; Pedigree; Phosphotransferases; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Xanthines

1990
Avian vitreous humor concentrations of inosine, hypoxanthine, xanthine, uric acid, uracil and uridine as influenced by age and sex: their relevance as indicators of ante-mortem hypoxia.
    Forensic science international, 1990, Volume: 47, Issue:2

    Topics: Age Factors; Animals; Chickens; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Postmortem Changes; Sex Factors; Uracil; Uric Acid; Uridine; Vitreous Body; Xanthine; Xanthines

1990
The effect of completely purine-free diet of low sodium content on purine intermediates and end-product.
    European journal of clinical nutrition, 1990, Volume: 44, Issue:9

    Topics: Adult; Erythrocytes; Humans; Hypoxanthines; Inosine; Male; Nucleosides; Nucleotides; Purines; Sodium, Dietary; Uric Acid

1990
Adenosine, inosine, and hypoxanthine/xanthine measured in tissue and plasma by a luminescence method.
    Clinical chemistry, 1990, Volume: 36, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Animals; Dogs; Humans; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Luminol; Pyridazines; Rabbits; Rats; Solutions; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

1990
Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity.
    Advances in experimental medicine and biology, 1989, Volume: 253A

    Topics: Adolescent; Adult; Child; Child, Preschool; Deafness; Female; Humans; Hypoxanthines; Inosine; Male; Pedigree; Phosphotransferases; Purine Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Xanthines

1989
Adenosine, inosine, hypoxanthine, xanthine and uric acid concentrations in the cerebrospinal fluid of unanaesthetized rats.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:3

    Topics: Adenosine; Anesthesia; Animals; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains; Uric Acid; Xanthines

1989
Hypoxanthine and xanthine transport through the blood-brain barrier in hypoxanthine phosphoribosyltransferase (HPRT) deficiency.
    Advances in experimental medicine and biology, 1989, Volume: 253A

    Topics: Allopurinol; Biological Transport; Blood-Brain Barrier; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Uric Acid; Xanthines

1989
Myogenic hyperuricemia: a comparative study between type V and type VII glycogenosis.
    Advances in experimental medicine and biology, 1989, Volume: 253A

    Topics: Adolescent; Adult; Exercise; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Glycogen Storage Disease Type VII; Humans; Hypoxanthines; Incidence; Inosine; Lactates; Male; Middle Aged; Muscles; Purines; Uric Acid

1989
Determination of rat cerebrospinal fluid concentrations of adenosine, inosine, hypoxanthine, xanthine and uric acid by high performance liquid chromatography.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:2

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Hypoxanthines; Inosine; Male; Nucleosides; Rats; Rats, Inbred Strains; Uric Acid; Xanthines

1988
Increased plasma uric acid after exercise in muscle phosphofructokinase deficiency.
    Neurology, 1986, Volume: 36, Issue:1

    Topics: Adult; Ammonia; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Muscular Diseases; Phosphofructokinase-1; Physical Exertion; Uric Acid; Veins

1986
Uptake and metabolism of [3H]adenosine by Aplysia ganglia and by individual neurons.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Animals; Aplysia; Chromatography, High Pressure Liquid; Cyclic AMP; Ganglia; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Neurons; Tissue Distribution; Uric Acid

1986
Potentiation of the chemotherapeutic action of 5'-deoxy-5-fluorouridine in combination with guanosine and related compounds.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:1

    Topics: Animals; Drug Synergism; Floxuridine; Guanine Nucleotides; Guanosine; Guanosine Monophosphate; Inosine; Leukemia P388; Leukemia, Experimental; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred Strains; Uric Acid

1987
Transport and metabolism of adenosine in the perfused guinea-pig placenta.
    The Journal of physiology, 1988, Volume: 405

    Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Female; Guinea Pigs; Hypoxanthine; Hypoxanthines; Inosine; Maternal-Fetal Exchange; Placenta; Pregnancy; Thioinosine; Tritium; Uric Acid

1988
Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1988, Volume: 8, Issue:5

    Topics: Adenosine; Animals; Cerebral Cortex; Coformycin; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides; Uric Acid; Xanthine; Xanthines

1988
Transmural differences in the postischemic recovery of cardiac energy metabolism.
    The American journal of pathology, 1988, Volume: 131, Issue:1

    Topics: Adenine Nucleotides; Animals; Coronary Disease; Energy Metabolism; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Reference Values; Uric Acid; Xanthine; Xanthines

1988
A reexamination of the effects induced by adenosine and its degradation products on rat fat cell lipolysis.
    Biochemical pharmacology, 1988, Sep-01, Volume: 37, Issue:17

    Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lipid Mobilization; Norepinephrine; Rats; Theophylline; Uric Acid

1988
Myogenic hyperuricemia. A common pathophysiologic feature of glycogenosis types III, V, and VII.
    The New England journal of medicine, 1987, Jul-09, Volume: 317, Issue:2

    Topics: Adult; Ammonia; Glycogen Storage Disease; Glycogen Storage Disease Type III; Glycogen Storage Disease Type V; Glycogen Storage Disease Type VII; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Muscles; Physical Exertion; Rest; Uric Acid

1987
Plasma and cerebrospinal fluid nucleosides and oxypurines in acute liver failure.
    The Journal of laboratory and clinical medicine, 1987, Volume: 110, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Guanosine; Hepatectomy; Hypoxanthine; Hypoxanthines; Inosine; Liver; Liver Diseases; Pyrimidine Nucleosides; Rabbits; Uric Acid

1987
Chemiluminescent determination of adenosine, inosine, and hypoxanthine/xanthine.
    Analytical biochemistry, 1987, May-15, Volume: 163, Issue:1

    Topics: Adenosine; Adipose Tissue; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Oxidation-Reduction; Uric Acid; Xanthine; Xanthines

1987
Liquid chromatography with multichannel ultraviolet detection used for studying disorders of purine metabolism.
    Clinical chemistry, 1987, Volume: 33, Issue:11

    Topics: Adenine; Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Oxypurinol; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthine; Xanthines

1987
[Mechanism of exercise-induced hyperuricemia].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1987, Volume: 49, Issue:5

    Topics: Adult; Ammonia; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Physical Exertion; Purines; Uric Acid; Xanthine; Xanthines

1987
Myocardial adenosine cycling rates during normoxia and under conditions of stimulated purine release.
    The Biochemical journal, 1986, Apr-01, Volume: 235, Issue:1

    Topics: Acetates; Acetic Acid; Adenosine; Animals; In Vitro Techniques; Inosine; Male; Myocardium; Oxygen; Purines; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tubercidin; Uric Acid

1986
[Destruction of muscle tissue and purine compound metabolism in hereditary muscular dystrophy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:11

    Topics: Adenine Nucleotides; Animals; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Mice; Muscles; Muscular Dystrophies; Purines; Uric Acid; Xanthine; Xanthines

1986
[Cerebrospinal fluid concentrations of creatinine and purine metabolites determined by high performance liquid chromatography: preliminary report on head injury and stroke patients].
    No shinkei geka. Neurological surgery, 1987, Volume: 15, Issue:1

    Topics: Adenosine; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Craniocerebral Trauma; Creatinine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Uric Acid

1987
Excess purine degradation in exercising muscles of patients with glycogen storage disease types V and VII.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:2

    Topics: Adult; Ammonia; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Glycogen Storage Disease Type VII; Glycolysis; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Models, Biological; Muscles; Physical Exertion; Purines; Uric Acid

1985
The liver is an organ site for the release of inosine metabolized by non-glycolytic pig red cells.
    Biochimica et biophysica acta, 1985, Mar-08, Volume: 838, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Energy Metabolism; Erythrocytes; Glycolysis; Hypoxanthine; Hypoxanthines; Inosine; Liver; Swine; Swine, Miniature; Uric Acid

1985
Human cyclic hematopoiesis is associated with aberrant purine metabolism.
    The Journal of laboratory and clinical medicine, 1985, Volume: 105, Issue:4

    Topics: Adenosine Deaminase; Adult; Agranulocytosis; Child; Chromatography, High Pressure Liquid; Chronic Disease; Female; Guanosine Triphosphate; Hematocrit; Hematopoiesis; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Neutropenia; Nucleosides; Nucleotides; Purines; Pyrimidines; Uric Acid

1985
[Xanthine-oxidoreductase (E.C.1.2.3.2.) activity in riboflavin or thiamine deficient rat liver].
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1971, Volume: 41, Issue:2

    Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Creatinine; Diet; DNA; Evaluation Studies as Topic; Inosine; Liver; Male; Methods; Methylene Blue; NAD; Phosphorus; Proteins; Rats; Riboflavin Deficiency; Stimulation, Chemical; Thiamine Deficiency; Uric Acid; Xanthine Oxidase; Xanthines

1971
Adsorption chromatography of cyclic nucleotides on silica gel and alumina thin-layer sheets.
    Analytical biochemistry, 1974, Volume: 58, Issue:1

    Topics: Adenine Nucleotides; Aluminum; Animals; Carbon Radioisotopes; Cattle; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Evaluation Studies as Topic; Female; Guanine Nucleotides; Hypoxanthines; Inosine; Male; Methods; Phosphorus Radioisotopes; Silicon Dioxide; Testis; Tritium; Uric Acid; Xanthines

1974
Urate synthesis in the perfused chick liver.
    The Biochemical journal, 1974, Volume: 144, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonium Chloride; Animals; Aspartic Acid; Carbon Radioisotopes; Chickens; Glutamine; Glycine; Inosine; Inosine Monophosphate; Insulin; Liver; Oxygen Consumption; Perfusion; Phosphoribosyl Pyrophosphate; Ribonucleosides; Tritium; Uric Acid; Xanthines

1974
Inhibition of adenosine uptake by platelets.
    Nature: New biology, 1972, Oct-18, Volume: 239, Issue:94

    Topics: Adenine; Adenosine; Blood Platelets; Buffers; Carbon Isotopes; Dipyridamole; Drug Synergism; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Uric Acid

1972
Experimentally induced alterations in affinity of hemoglobin for oxygen. II. In vivo effect of inosine, pyruvate, and phosphate on oxygen-hemoglobin affinity in rhesus monkey.
    Blood, 1972, Volume: 39, Issue:4

    Topics: Animals; Calcium; Glycerophosphates; Haplorhini; Hemoglobins; Inosine; Macaca; Nucleosides; Oxygen Consumption; Phosphates; Phosphorus; Potassium; Pyruvates; Sodium; Uric Acid

1972
Comparative effect of intravenously administered nitrogenous compounds on uric acid synthesis in chickens fed a 20 per cent protein diet.
    The Journal of nutrition, 1973, Volume: 103, Issue:8

    Topics: Acetates; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Chickens; Dietary Proteins; Glutamates; Glutamine; Glycine; Injections, Intravenous; Inosine; Lysine; Male; Nitrogen; Quaternary Ammonium Compounds; Sodium; Structure-Activity Relationship; Threonine; Time Factors; Uric Acid

1973
Adenosine metabolism in platelets and plasma.
    Series haematologica (1968), 1973, Volume: 6, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Animals; Anticoagulants; Binding Sites; Blood Cell Count; Blood Platelets; Buffers; Carbon Radioisotopes; Centrifugation, Density Gradient; Depression, Chemical; Dipyridamole; Guinea Pigs; Humans; Hypoxanthines; Inosine; Lithium; Platelet Adhesiveness; Prostaglandins; Rabbits; Rats; Receptors, Drug; Species Specificity; Temperature; Time Factors; Uric Acid

1973
A screening test for urinary purines and pyrimidines and related compounds using auxotrophic mutants of Escherichia coli K12.
    Biochemical medicine, 1970, Volume: 3, Issue:4

    Topics: Adenine; Alanine; Aspartic Acid; Biological Assay; Carbamates; Child; Chromatography, Paper; Cytosine; Escherichia coli; Glycosides; Humans; Imidazoles; Inosine; Mutation; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Purinones; Pyrimidines; Ribose; Thymine; Uracil; Uric Acid

1970
Phylogenetic aspects of purine metabolism.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Jul-15, Volume: 46, Issue:29

    Topics: Allantoin; Ammonia; Amphibians; Animals; Biological Evolution; Birds; Hypoxanthines; Inosine; Invertebrates; Mammals; Nitrogen; Oxygen Consumption; Purines; Reptiles; Urea; Uric Acid; Xanthine Oxidase

1972
Enhanced ATP and GTP synthesis from hypoxanthine or inosine after myocardial ischemia.
    The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 2

    Topics: Adenosine Triphosphate; Animals; Coronary Disease; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Male; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines

1984
Adenine nucleotide levels and adenosine metabolism in cultured calvarial bone.
    Acta physiologica Scandinavica, 1984, Volume: 120, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone and Bones; Cells, Cultured; Deoxyadenosines; Dinoprostone; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Mice; Parathyroid Hormone; Prostaglandins E; Uric Acid

1984
High performance liquid chromatographic profiles of nucleosides, bases and tryptophan in the plasma of the Tasmanian devil and four other marsupial species.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1984, Volume: 79, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Marsupialia; Opossums; Species Specificity; Tryptophan; Uric Acid

1984
Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:12

    Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Contracture; Coronary Disease; Energy Metabolism; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Inosine Monophosphate; Male; Myocardium; Rats; Rats, Inbred Strains; Uric Acid

1984
[Changes of the acid-base status, serum lactate concentration and purine metabolism in reconstructive arterial surgery].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1983, Volume: 54, Issue:11

    Topics: Acid-Base Equilibrium; Adenosine; Aorta, Abdominal; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Middle Aged; Purines; Pyruvates; Pyruvic Acid; Uric Acid; Xanthine; Xanthines

1983
[Degradation of purine nucleotides in hereditary xanthinuria by rapid infusion of fructose: preliminary results].
    Medicina clinica, 1983, Nov-05, Volume: 81, Issue:14

    Topics: Adolescent; Adult; Child; Female; Fructose; Humans; Inosine; Male; Uric Acid; Xanthines

1983
Cerebrospinal fluid concentrations of hypoxanthine, xanthine, uridine and inosine: high concentrations of the ATP metabolite, hypoxanthine, after hypoxia.
    Journal of clinical pathology, 1983, Volume: 36, Issue:1

    Topics: Adult; Asphyxia Neonatorum; Brain Damage, Chronic; Female; Fetal Hypoxia; Humans; Hypoxanthines; Infant, Newborn; Inosine; Postmortem Changes; Pregnancy; Prognosis; Uric Acid; Uridine; Xanthines

1983
Diltiazem administered before or during myocardial ischemia decreases adenine nucleotide catabolism.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Benzazepines; Coronary Circulation; Coronary Disease; Diltiazem; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines

1984
Circadian variations of adenosine level in blood and liver and its possible physiological significance.
    Life sciences, 1983, Sep-12, Volume: 33, Issue:11

    Topics: Adenosine; Animals; Circadian Rhythm; Energy Metabolism; Hypoxanthine; Hypoxanthines; Inosine; Liver; Male; Phosphorylation; Purines; Rats; Rats, Inbred Strains; Uric Acid

1983
Uric acid formation in the dog lung.
    Molecular and cellular biochemistry, 1982, Mar-19, Volume: 43, Issue:2

    Topics: Animals; Dogs; Heart Arrest, Induced; Inosine; Lung; Time Factors; Uric Acid

1982
The measurement of hypoxanthine, xanthine, inosine and uridine in umbilical cord blood and fetal scalp blood samples as a measure of fetal hypoxia.
    British journal of obstetrics and gynaecology, 1981, Volume: 88, Issue:4

    Topics: Female; Fetal Blood; Fetal Hypoxia; Humans; Hypoxanthines; Infant, Newborn; Inosine; Pregnancy; Scalp; Uric Acid; Uridine; Xanthines

1981
Effect of adenosine metabolites on methyltransferase reactions in isolated rat livers.
    Biochimica et biophysica acta, 1981, Dec-04, Volume: 678, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Animals; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Liver; Male; Methyltransferases; Perfusion; Rats; S-Adenosylhomocysteine; Uric Acid

1981
Methotrexate with thymidine, inosine, and allopurinol rescue: a phase I clinical study.
    Cancer treatment reports, 1981, Volume: 65 Suppl 1

    Topics: Adult; Aged; Allopurinol; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypoxanthines; Infusions, Parenteral; Inosine; Male; Methotrexate; Middle Aged; Thymidine; Uric Acid

1981
Comparison of high-performance liquid chromatographic serum profiles of humans and dogs.
    Journal of chromatography, 1980, Feb-08, Volume: 181, Issue:2

    Topics: Animals; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Creatinine; Dogs; Humans; Hypoxanthines; Inosine; Kynurenine; Male; Nucleosides; Purines; Tryptophan; Tyrosine; Uric Acid; Xanthines

1980
Purine metabolism during strenuous muscular exercise in man.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:3

    Topics: Adenine Nucleotides; Adult; Aged; Allopurinol; Blood Chemical Analysis; Humans; Inosine; Male; Middle Aged; Muscles; Physical Exertion; Purinones; Uric Acid

1980
Abnormal purine and pyrimidine metabolism in inherited superactivity of PRPP synthetase.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Adenine Nucleotides; Allopurinol; Child; Erythrocytes; Female; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; NAD; Nuclear Family; Purine-Pyrimidine Metabolism, Inborn Errors; Reference Values; Ribonucleotides; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Uridine; Uridine Diphosphate Glucose; Xanthine; Xanthines

1994
Determination of plasma purine nucleoside phosphorylase activity by high-performance liquid chromatography.
    Analytical biochemistry, 1995, May-01, Volume: 227, Issue:1

    Topics: Adult; Aged; Asthma; Calibration; Chromatography, High Pressure Liquid; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Purine-Nucleoside Phosphorylase; Thiazoles; Uric Acid; Xanthine Oxidase

1995
Transfer of dideoxyinosine across the human isolated placenta.
    British journal of clinical pharmacology, 1994, Volume: 38, Issue:3

    Topics: Antipyrine; Biological Transport; Chromatography, High Pressure Liquid; Didanosine; Female; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Uric Acid; Zidovudine

1994
Comparison of energy metabolism in rat liver grafts during preservation in University of Wisconsin or Euro-Collins solutions.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Energy Metabolism; Glutathione; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Inosine; Insulin; Lactates; Liver; Liver Transplantation; Male; Microdialysis; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Time Factors; Uric Acid; Xanthine; Xanthines

1995
Adenosine metabolism in vivo.
    Proceedings of the Western Pharmacology Society, 1994, Volume: 37

    Topics: Adenosine; Animals; Cats; Chromatography, High Pressure Liquid; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Uric Acid

1994
High performance liquid chromatography analysis of hypoxanthine metabolism in mouse oocyte-cumulus cell complexes: effects of purine metabolic perturbants.
    Biology of reproduction, 1994, Volume: 50, Issue:6

    Topics: Adenylosuccinate Synthase; Alanine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Meiosis; Mercaptopurine; Mice; Mycophenolic Acid; Oocytes; Purine-Nucleoside Phosphorylase; Purines; Uric Acid; Xanthine Oxidase

1994
The effect of high-intensity training on purine metabolism in man.
    Acta physiologica Scandinavica, 1993, Volume: 149, Issue:4

    Topics: Adult; AMP Deaminase; Exercise; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Male; Muscles; Phosphofructokinase-1; Purines; Uric Acid

1993
Exchange of purines in human liver and skeletal muscle with short-term exhaustive exercise.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 2

    Topics: Adult; Humans; Hypoxanthine; Hypoxanthines; Inosine; Liver; Male; Muscles; Oxygen Consumption; Physical Endurance; Physical Exertion; Purines; Time Factors; Uric Acid; Xanthine; Xanthines

1994
Renal hypouricemia with both drug-insensitive secretion and defective reabsorption of urate: a novel type of renal hypouricemia.
    Nephron, 1993, Volume: 64, Issue:3

    Topics: Adult; Creatinine; Drug Resistance; Extracellular Space; Furosemide; Humans; Inosine; Kidney Diseases; Kidney Tubules; Male; Prednisolone; Pyrazinamide; Uric Acid

1993
Mechanisms of adenine nucleotide depletion from endothelial cells exposed to reactive oxygen metabolites.
    Free radical biology & medicine, 1993, Volume: 14, Issue:2

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Inosine; Reactive Oxygen Species; Superoxides; Umbilical Veins; Uric Acid; Xanthine Oxidase

1993
Concentration of purine compounds in the cerebrospinal fluid of infants suffering from sepsis, convulsions and hydrocephalus.
    Journal of perinatal medicine, 1995, Volume: 23, Issue:3

    Topics: Adenine; Bacterial Infections; Chromatography, High Pressure Liquid; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Inosine; Predictive Value of Tests; Purines; Seizures; Uric Acid; Xanthine; Xanthines

1995
Simultaneous determination of adenosine, inosine, hypoxanthine, xanthine, and uric acid in microdialysis samples using microbore column high-performance liquid chromatography with a diode array detector.
    Analytical biochemistry, 1996, Jun-15, Volume: 238, Issue:1

    Topics: Adenosine; Animals; Calibration; Chromatography, High Pressure Liquid; Dogs; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Microdialysis; Myocardial Reperfusion Injury; Sensitivity and Specificity; Time Factors; Uric Acid; Xanthine; Xanthines

1996
Temporal variations of adenosine metabolism in human blood.
    Chronobiology international, 1996, Volume: 13, Issue:3

    Topics: 5'-Nucleotidase; Acclimatization; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylhomocysteinase; Adult; Analysis of Variance; Blood Glucose; Circadian Rhythm; Humans; Hydrolases; Hypoxanthine; Inosine; Lactates; Male; Uric Acid

1996
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:3

    Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Purines; Uric Acid; Xanthine; Xanthines

1997
Response of purine metabolism and cortical oxygen pressure to hypoxia and reoxygenation in newborn piglets.
    Advances in experimental medicine and biology, 1997, Volume: 428

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Hypoxanthine; Hypoxia; Inosine; Oxygen; Partial Pressure; Purines; Swine; Uric Acid; Xanthine

1997
The effects of nucleotide pool on purine production in the postischemic heart.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Adenosine Triphosphate; Animals; Hypoxanthine; Inosine; Kinetics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purine Nucleotides; Purines; Rats; Time Factors; Uric Acid; Xanthine

1998
Different mechanism of myocardial nucleotide breakdown during normothermic and hypothermic ischemia.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Animals; Heart Arrest, Induced; Hypoxanthine; In Vitro Techniques; Inosine; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nucleotides; Rats; Temperature; Time Factors; Uric Acid; Xanthine

1998
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:6

    Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; Hemodynamics; Hypoxanthine; Hypoxia; Inosine; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Ischemia; Potassium Channels; Uric Acid; Xanthine

1998
Can oxypurines plasma levels classify the type of physical exercise?
    The Journal of sports medicine and physical fitness, 1999, Volume: 39, Issue:2

    Topics: Ammonia; Analysis of Variance; Chromatography, High Pressure Liquid; Exercise; Humans; Hypoxanthine; Inosine; Lactic Acid; Muscle Fatigue; Uric Acid; Xanthine

1999
Purine loss after repeated sprint bouts in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:6

    Topics: Adult; Humans; Hypoxanthine; Inosine; Male; Osmolar Concentration; Purines; Running; Uric Acid

1999
A simple high-performance liquid chromatography assay for simultaneous measurement of adenosine, guanosine, and the oxypurine metabolites in plasma.
    Therapeutic drug monitoring, 2000, Volume: 22, Issue:2

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Guanosine; Humans; Hypoxanthine; Inosine; Purines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Uric Acid; Xanthine

2000
Plasma purine turnover metabolites in women with normal pregnancy and pregnancy complicated with induced hypertension as compared to fetal well-being indices.
    Journal of perinatal medicine, 2000, Volume: 28, Issue:5

    Topics: Adult; Apgar Score; Blood Pressure; Diastole; Female; Gestational Age; Heart Rate, Fetal; Humans; Hypertension; Hypoxanthine; Infant, Newborn; Inosine; Pregnancy; Pregnancy Complications, Cardiovascular; Purines; Systole; Uric Acid; Xanthine

2000
Glutathione deficiency potentiates manganese-induced increases in compounds associated with high-energy phosphate degradation in discrete brain areas of young and aged rats.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:6

    Topics: Aging; Animals; Antimetabolites; Ascorbic Acid; Brain; Buthionine Sulfoximine; Dehydroascorbic Acid; Drug Synergism; Energy Metabolism; Glutathione; Hypoxanthine; Inosine; Male; Manganese; Phosphates; Rats; Rats, Wistar; Tissue Distribution; Uric Acid; Xanthine

2000
Blood purine and energy status in rats with colitis.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:2

    Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Energy Metabolism; Hemoglobins; Inosine; Male; Peroxidase; Purines; Rats; Rats, Wistar; Time Factors; Uric Acid

2001
Manipulation of plasma uric acid in broiler chicks and its effect on leukocyte oxidative activity.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:3

    Topics: Animals; Animals, Newborn; Chickens; Diet; Female; Hypoxanthine; Inosine; Kidney; Leukocytes; Liver; Male; Organ Size; Osmolar Concentration; Oxidation-Reduction; Pectoralis Muscles; Uric Acid

2002
Effect of inosine on the plasma concentration of uridine and purine bases.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:4

    Topics: Adult; Carcinoma, Hepatocellular; Creatinine; Dose-Response Relationship, Drug; Humans; Hypoxanthine; Inosine; Kinetics; Liver Neoplasms; Purines; Reference Values; Time Factors; Tumor Cells, Cultured; Uric Acid; Uridine; Xanthine

2002
Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-10, Volume: 99, Issue:25

    Topics: Administration, Oral; Animals; Biotransformation; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inosine; Inosine Monophosphate; Mice; Molsidomine; Monocytes; Multiple Sclerosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Oxonic Acid; Peroxynitrous Acid; Urate Oxidase; Uric Acid; Xanthines

2002
Allantoin, the oxidation product of uric acid is present in chicken and turkey plasma.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2003, Volume: 135, Issue:2

    Topics: Allantoin; Animals; Chickens; Hypoxanthine; Inosine; Male; Oxidation-Reduction; Oxidative Stress; Turkeys; Urate Oxidase; Uric Acid

2003
Interstitial purine metabolites in hearts with LV remodeling.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Hypoxanthine; Inosine; Isoproterenol; Kinetics; Male; Microdialysis; Models, Animal; Purines; Rats; Rats, Wistar; Uric Acid; Ventricular Function, Left; Ventricular Remodeling; Xanthine

2004
In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Cycle; Cells, Cultured; Cytoprotection; DNA Damage; DNA Glycosylases; DNA-Binding Proteins; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Hyperoxia; Inosine; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Uric Acid

2005
Intense exercise induces the degradation of adenine nucleotide and purine nucleotide synthesis via de novo pathway in the rat liver.
    European journal of applied physiology, 2006, Volume: 96, Issue:5

    Topics: Adenine Nucleotides; Allantoin; Animals; Carbon Radioisotopes; Glycine; Hypoxanthine; Inosine; Liver; Male; Nitrogen Isotopes; Physical Exertion; Purine Nucleotides; Rats; Rats, Wistar; Uric Acid

2006
Sprint training reduces urinary purine loss following intense exercise in humans.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2006, Volume: 31, Issue:6

    Topics: Adult; Humans; Hypoxanthine; Inosine; Male; Muscles; Osmolar Concentration; Physical Education and Training; Purines; Running; Time Factors; Uric Acid

2006
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs.
    Science (New York, N.Y.), 2007, Feb-23, Volume: 315, Issue:5815

    Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Base Sequence; Brain; HeLa Cells; Humans; Inosine; Liver; Mice; MicroRNAs; Molecular Sequence Data; Nucleic Acid Conformation; Organ Specificity; Protein Serine-Threonine Kinases; Ribose-Phosphate Pyrophosphokinase; RNA Editing; RNA Interference; RNA-Binding Proteins; Uric Acid

2007
Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:5

    Topics: Adenosine; Animals; Cell Movement; Chronic Disease; Endothelial Cells; Hyperuricemia; Inosine; Ischemia; Ischemic Preconditioning; Kidney; Mice; Mice, Inbred Strains; Oxonic Acid; Stem Cells; Urate Oxidase; Uric Acid

2007
Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function.
    Scandinavian journal of urology and nephrology, 2007, Volume: 41, Issue:2

    Topics: Female; Guanosine; Humans; Hypoxanthine; Inosine; Kidney Transplantation; Male; Middle Aged; Nucleosides; Predictive Value of Tests; Renal Veins; Reperfusion; Uric Acid; Uridine; Xanthine

2007
Transformation products of extracellular NAD(+) in the rat liver: kinetics of formation and metabolic action.
    Molecular and cellular biochemistry, 2008, Volume: 307, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Animals; Glucose; Infusion Pumps; Inosine; Liver; Male; NAD; Niacinamide; Pyruvic Acid; Rats; Rats, Wistar; Time Factors; Uric Acid

2008
Inosine ameliorates the effects of hemin-induced oxidative stress in broilers.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2008, Volume: 151, Issue:4

    Topics: Animals; Animals, Newborn; Chickens; Female; Hemin; Inosine; Kidney; Leukocytes; Male; Oxidative Stress; Uric Acid

2008
Correlations of six related purine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.
    Clinical biochemistry, 2009, Volume: 42, Issue:3

    Topics: Adenosine; Aged; Asian People; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Inosine; Male; Middle Aged; Purines; Uric Acid; Xanthine

2009
Transformation and action of extracellular NAD+ in perfused rat and mouse livers.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Gluconeogenesis; Inosine; Liver; Male; Mice; NAD; Niacinamide; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Rats, Wistar; Uric Acid

2009
The treatment of multiple sclerosis with inosine.
    Journal of alternative and complementary medicine (New York, N.Y.), 2009, Volume: 15, Issue:6

    Topics: Humans; Inosine; Multiple Sclerosis; Uric Acid

2009
Blood uridine concentration may be an indicator of the degradation of pyrimidine nucleotides during physical exercise with increasing intensity.
    Journal of physiology and biochemistry, 2010, Volume: 66, Issue:3

    Topics: Exercise; Exercise Test; Humans; Hypoxanthines; Inosine; Lactic Acid; Male; Muscle, Skeletal; Purines; Pyrimidine Nucleotides; Rest; Uric Acid; Uridine; Young Adult

2010
Selective determination of inosine in the presence of uric acid and hypoxanthine using modified electrode.
    Analytical biochemistry, 2012, Feb-01, Volume: 421, Issue:1

    Topics: Biosensing Techniques; Electrochemical Techniques; Electrodes; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Inosine; Microscopy, Atomic Force; Oxidation-Reduction; Triazoles; Uric Acid

2012
Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides.
    European journal of pharmacology, 2012, Sep-05, Volume: 690, Issue:1-3

    Topics: Animals; Biological Transport; Cebus; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Furans; Gene Expression Regulation; HeLa Cells; Humans; Inosine; Intestinal Absorption; Male; Membrane Transport Proteins; Purine Nucleosides; Rats; Rats, Sprague-Dawley; Renal Tubular Transport, Inborn Errors; RNA, Fungal; Uric Acid; Urinary Calculi

2012
Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders.
    Neuro-degenerative diseases, 2013, Volume: 12, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Brain; Case-Control Studies; Female; Humans; Inosine; Lewy Body Disease; Male; Parkinson Disease; Postmortem Changes; Purines; Regression Analysis; Sex Factors; Signal Transduction; Uric Acid; Xanthine

2013
Urate-induced acute renal failure and chronic inflammation in liver-specific Glut9 knockout mice.
    American journal of physiology. Renal physiology, 2013, Sep-01, Volume: 305, Issue:5

    Topics: Acute Kidney Injury; Animals; Crystallization; Diet, High-Fat; Glucose Transport Proteins, Facilitative; Hydrogen-Ion Concentration; Hyperuricemia; Inflammation; Inosine; Male; Mice; Mice, Knockout; Organic Anion Transporters; Uric Acid; Urine

2013
Protection by inosine in a cellular model of Parkinson's disease.
    Neuroscience, 2014, Aug-22, Volume: 274

    Topics: Animals; Antiparkinson Agents; Astrocytes; Cell Line; Cell Survival; Cells, Cultured; Coculture Techniques; Dopaminergic Neurons; Free Radicals; Hydrogen Peroxide; Inosine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitrites; Oxidative Stress; Parkinsonian Disorders; Protein Carbonylation; Purines; Rats; Uric Acid

2014
A novel method for measuring the ATP-related compounds in human erythrocytes.
    The Tohoku journal of experimental medicine, 2014, Volume: 233, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Erythrocyte Count; Erythrocytes; Homeostasis; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Inosine; Inosine Monophosphate; Sensitivity and Specificity; Uric Acid

2014
Screening and characterization of purine nucleoside degrading lactic acid bacteria isolated from Chinese sauerkraut and evaluation of the serum uric acid lowering effect in hyperuricemic rats.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Bile Acids and Salts; Brassica; Diet; Fermentation; Gastrointestinal Tract; Guanosine; Humans; Hydrogen Peroxide; Hyperuricemia; Inosine; Lactic Acid; Lactobacillaceae; Lactobacillus plantarum; Male; Microbial Sensitivity Tests; Probiotics; Rats; Rats, Wistar; RNA, Ribosomal, 16S; Uric Acid

2014
Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.
    Biochemical pharmacology, 2015, Sep-01, Volume: 97, Issue:1

    Topics: Aging; Allopurinol; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Dimerization; Enzyme Induction; Enzyme Inhibitors; Gout Suppressants; Humans; Hyperuricemia; Hypoxanthine; Ileum; Inosine; Intestinal Elimination; Intestinal Mucosa; Male; Mitochondria; Neoplasm Proteins; Rats, Wistar; Reactive Oxygen Species; Uric Acid; Xanthine Oxidase

2015
Uricosuric agents decrease the plasma urate level in rats by concomitant treatment with topiroxostat, a novel xanthine oxidoreductase inhibitor.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:1

    Topics: Animals; Drug Therapy, Combination; Enzyme Inhibitors; Inosine; Male; Nitriles; Oxonic Acid; Probenecid; Pyridines; Rats; Rats, Wistar; Urate Oxidase; Uric Acid; Uricosuric Agents; Xanthine Dehydrogenase

2016
Oral Inosine Persistently Elevates Plasma antioxidant capacity in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2016, Volume: 31, Issue:3

    Topics: Antioxidants; Disease Progression; Female; Humans; Inosine; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Treatment Outcome; Uric Acid

2016
Hypercrosslinked strong cation-exchange polymers for selective extraction of serum purine metabolites associated with gout.
    Talanta, 2016, May-01, Volume: 151

    Topics: Cation Exchange Resins; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Gout; Humans; Hypoxanthine; Inosine; Microscopy, Electron, Scanning; Polymers; Purines; Reproducibility of Results; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared; Uric Acid; Xanthine

2016
Simultaneous quantification by HPLC of purines in umami soup stock and evaluation of their effects on extracellular and intracellular purine metabolism.
    Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Food; Food Ingredients; Guanosine; Hep G2 Cells; Humans; Hypoxanthine; Inosine; Purines; Uric Acid; Xanthine

2018
Simultaneous detection of ATP metabolites in human plasma and urine based on palladium nanoparticle and poly(bromocresol green) composite sensor.
    Biosensors & bioelectronics, 2019, Feb-01, Volume: 126

    Topics: Adenosine Triphosphate; Biosensing Techniques; Humans; Hypoxanthine; Inosine; Metabolome; Metal Nanoparticles; Nanotubes, Carbon; Palladium; Uric Acid; Xanthine

2019
A defect in purine nucleotide metabolism in the silkworm, Bombyx mori, causes a translucent larval integument and male infertility.
    Insect biochemistry and molecular biology, 2020, Volume: 126

    Topics: Animals; Bombyx; CRISPR-Cas Systems; Infertility, Male; Inosine; Inosine Monophosphate; Integumentary System; Larva; Male; Moths; Mutation; Nitrogen; Nucleotidases; Purine Nucleotides; RNA-Seq; Uric Acid

2020
Improved ultra-high performance liquid chromatographic method for simultaneous determination of five gout-related metabolites in human serum.
    Journal of separation science, 2021, Volume: 44, Issue:5

    Topics: Chromatography, High Pressure Liquid; Creatinine; Gout; Humans; Hypoxanthine; Inosine; Uric Acid; Xanthine

2021
Inosine induces acute hyperuricaemia in rhesus monkey (
    Pharmaceutical biology, 2021, Volume: 59, Issue:1

    Topics: Acute Disease; Allopurinol; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Febuxostat; Hyperuricemia; Imino Furanoses; Inosine; Macaca mulatta; Male; Pyrimidinones; Reproducibility of Results; Uric Acid

2021
Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia- reperfusion injury.
    Cardiovascular research, 2022, 10-21, Volume: 118, Issue:13

    Topics: Animals; beta-Alanine; Carnosine; Carrier Proteins; Chromatography, Liquid; Infarction; Inosine; Iron; Ischemia; Ketoglutaric Acids; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Nuclear Proteins; Nucleotides; Oxygenases; Phosphates; Proline; Proteome; Purine Nucleotides; Pyrimidines; Ribosomal Proteins; Tandem Mass Spectrometry; Uric Acid

2022
Effect of Urate-Elevating Inosine on Progression of Early Parkinson Disease-Reply.
    JAMA, 2022, 01-04, Volume: 327, Issue:1

    Topics: Disease Progression; Humans; Inosine; Parkinson Disease; Uric Acid

2022
Effect of Urate-Elevating Inosine on Progression of Early Parkinson Disease.
    JAMA, 2022, 01-04, Volume: 327, Issue:1

    Topics: Disease Progression; Humans; Inosine; Parkinson Disease; Uric Acid

2022
Altered purine metabolism at reperfusion affects clinical outcome in lung transplantation.
    Thorax, 2023, Volume: 78, Issue:3

    Topics: Humans; Inosine; Lung; Lung Transplantation; Reperfusion; Reperfusion Injury; Uric Acid

2023
Dissecting the Domains of Parkinson's Disease: Insights from Longitudinal Item Response Theory Modeling.
    Movement disorders : official journal of the Movement Disorder Society, 2022, Volume: 37, Issue:9

    Topics: Bayes Theorem; Humans; Inosine; Levodopa; Parkinson Disease; Severity of Illness Index; Tremor; Uric Acid

2022