uric acid and benzbromarone

uric acid has been researched along with benzbromarone in 208 studies

Research

Studies (208)

Timeframe	Studies, this research(%)	All Research%
pre-1990	70 (33.65)	18.7374
1990's	38 (18.27)	18.2507
2000's	24 (11.54)	29.6817
2010's	52 (25.00)	24.3611
2020's	24 (11.54)	2.80

Authors

Authors	Studies
Endou, H; Hosoya, T; Hosoyamada, M; Ichida, K; Kimura, H; Takeda, M; Utsunomiya, Y	1
Ashizawa, N; Iwanaga, T; Kobashi, S; Matsumoto, K; Miyata, S; Uda, J	1
Mertz, DP	5
Didier, M; Olmer, M	1
Fanelli, GM	1
Berg, G; Matzkies, F; Minzlaff, R	1
Flury, W; Montandon, A; Ruch, HR	1
Avery, GS; Brogden, RN; Heel, RC; Speight, TM	1
Arntz, HR; Dreykluft, HR; Leonhardt, H	1
König, HJ	1
Bresnik, W; Kuzmits, R; Müller, MM	1
Barsom, S	1
Giudicelli, C; Masbernard, A; Meunier, J; Ricordel, I; Schermann, JM	1
Kleinschmidt, A; Schräpler, P; Schulz, E	1
Haese, E; Kleinschmidt, A; Schräpler, P	1
Matzkies, F	4
Flügel, M; Geldmacher, J	1
Akaoka, I; Masuda, T; Nishida, Y; Nishizawa, T	1
Bröll, H; Eberl, R; Sochor, H; Tausch, G	1
Enzensberger, W; Greiling, H; Stuhlsatz, HW	1
Fox, IH; Sinclair, DS	2
Bec, Ph; Pujo, JM; Suc, JM	1
Berg, G; Matzkies, F	2
Janzen, D; Kühnhold, O; Mertz, DP; Scheiffele, E	1
Berg, G; Matzkies, F; Neuwirth, R	1
Yu, TF	1
Schräpler, P; Schulz, E	1
Siegenthaler-Zuber, G	1
Inagaki, H; Nakai, T; Shinosaki, T; Yamashita, T; Yonetani, Y	1
Agbedana, EO; Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T	1
Akaoka, I; Fujimori, S; Kaneko, K	1
Empl, H; Gresser, U; Kamilli, I; Zöllner, N	1
Agbedana, OE; Hada, T; Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T	1
Tykarski, A	1
Gresser, U	1
Berg, H	1
Binswanger, U; Hess, B	1
Akiyama, T; Ikegami, M; Imanishi, M; Ishii, T; Kanda, H; Kunikata, S; Kurita, T; Matsuura, T; Nishioka, T; Uemura, T	1
Malý, J; Schück, O	1
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T	2
Goto, H; Ito, A; Mikami, T	1
Hasegawa, J; Hisatome, I; Ishiko, R; Kotake, H; Mashiba, H; Nakamoto, S; Ogino, K; Saito, M	1
Cabo, J; Gomez-Ruiz, MD; Izquierdo, R; Rodilla, F; Sanchez-Beltran, MJ	1
de Vries, JX; Ittensohn, A; Kohlmeier, M; Walter-Sack, I; Weber, E	1
Hasegawa, J; Hisatome, I; Kotake, H; Mashiba, H; Miyamoto, J; Nakamoto, S; Ogino, K; Saito, M	1
Hesse, A; Schneeberger, W; Vahlensieck, W	1
Schoeman, HS; Sommers, DK	1
Malý, J	1
Clavel, JP; Colin, JN; Dietlin, F; Farinotti, R; Fredj, G; Tod, M; Vignon, E	1
Hwang, TJ; Ito, M; Kuroda, Y; Miyao, M; Naito, E; Takeda, E; Toshima, K; Watanabe, T; Yokota, I	1
Eichhorn, R; Mertz, DP	1
Gröbner, W; Löffler, W; Zöllner, N	1
Homma, Y; Kitamura, T; Nishimura, Y	1
Rodnan, GP	1
Diehm, C; Mörl, H; Schöffel, G; Walter, E; Zimmermann, R	1
Chandelier, C; Dupuich, Y; Niquet, G	1
Brzozowska-Jurkowska, AM; Kawenoki-Minc, E	1
Brzozowska-Jurkowska, AM	1
Bluestone, R; Klinenberg, J; Lee, IK	1
Bader, U; Ferber, H; Matzkies, F	1
Scott, WA	1
Schepers, GW	1
Dorn, M	1
Kuroda, M; Takeda, R; Tofuku, Y	1
Sailer, D	1
Giudicelli, CP; Masbernard, A	1
Levinson, DJ; Sorensen, LB	3
Angar, T; Bach, GL; Grosse-Kielisch, C; Jelke, K; Jüttner, A; Krause, G; Neubauer, M	1
Asch, G; Asch, L	1
Danĕková, H; Dzúrik, R; Fedelesová, V; Hlavatá, E	1
Asch, L; Schirardin, H; Weryha, A	1
Bach, D; Hesse, A; Strenge, A; Vahlensieck, W	1
Gathof, BS; Gresser, U; Gross, M	1
Hiroshige, K; Kuroiwa, A; Takasugi, M; Yuu, K	1
Kawai, S; Osawa, G; Yamada, M	1
Bock, HA; Thiel, G; Zürcher, RM	1
Balkarov, IM	1
Posadzy-Małaczyńska, A; Pupek-Musialik, D; Tykarski, A	1
Fujimoto, Y; Hirata, N; Hisatome, I; Kosaka, H; Kotake, H; Mashiba, H; Sato, R; Shigemasa, C; Tanaka, Y; Yoshida, A	1
de Vries, JX; Empl, H; Gresser, U; Ittensohn, A; Walter-Sack, I; Weber, E; Zöllner, N	1
Hiroshige, K; Kuroiwa, A; Soejima, M; Takasugi, M; Yuu, K	1
Groenewoud, G; Hundt, HK; Müller, FO; Schall, R; van der Merwe, JC; van Dyk, M	1
Fujimoto, Y; Hisatome, I; Igawa, O; Kosaka, H; Manabe, I; Ohtahara, A; Ohtahara, K; Sawaguchi, M; Shigemasa, C; Takeda, A; Tanaka, Y; Tsuboi, M; Yoshida, A	1
Higashino, K; Hiroishi, K; Moriwaki, Y; Naito, Y; Nasako, Y; Takahashi, S; Yamakita, J; Yamamoto, T	1
Diezi, J; Guisan, B; Roch-Ramel, F	1
Fujita, K; Hirasaki, S; Koide, N; Ogawa, H; Tsuji, T	1
Goriki, K; Ochiai, M; Okusaki, K; Takahashi, H; Toda, K; Tokunou, H; Uehara, S	1
de Vries, JX; Pfleilschifter, V; Raedsch, R; von Bubnoff, A; Walter-Sack, I	1
Hirai, A; Saito, Y	1
Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T	2
Hamada, N; Hiroe, K; Hisatome, I; Kato, T; Kinugawa, T; Manabe, I; Ogino, K; Ohtahara, A; Sato, R; Shigemasa, C; Shimoyama, M; Takeda, A; Tanaka, Y; Tsuboi, M; Yamamoto, Y; Yoshida, A	1
Grahame, R; Marsh, FP; McBride, MB; Simmonds, HA	1
Fend, F; Gruber, J; König, P; Lhotta, K; Sgonc, R	1
Decaux, G; Hannotier, P; Musch, W; Prospert, F; Soupart, A	1
Alonso-Ruiz, A; Calabozo, M; García-Erauskin, G; Herrero-Beites, A; Perez-Ruiz, F; Ruiz-Lucea, E	1
Chazerain, P; Ziza, JM	1
Furuyama, T; Ikarashi, T; Ito, S; Kurihara, I; Miura, R; Saito, T; Sato, H; Sato, M; Soma, J; Suzuki, T; Tsunoda, K	1
Ito, A; Mikami, T; Yoshino, Y	1
Calabozo, M; García-Erauskin, G; Herrero-Beites, AM; Perez-Ruiz, F; Pijoan, JI	1
Gröbner, W; Walter-Sack, I	1
Arai, M; Fujiwara, K; Hirasawa, H; Kanda, T; Kojima, H; Saisho, H; Yokosuka, O	1
Akkasilpa, S; Deesomchok, U; Hanvivadhanakul, P	1
Calabozo, M; Herrero-Beites, AM; Perez-Ruiz, F; Pijoan, JI; Ruibal, A	1
Hasegawa, Y; Ito, O; Ito, S; Kudo, K; Mitsui, H; Sato, H; Sato, K; Yuda, F	1
Akkasilpa, S; Avihingsanon, Y; Deesomchok, U; Osiri, M	1
Gow, P; Kumar, S; Ng, J	1
Wong, ML	1
Hirayama, M; Iwanaga, T; Kobayashi, D; Maeda, T; Tamai, I	1
Hosoyamada, M; Ichida, K; Shibasaki, T	1
Atxotegi, J; Calabozo, M; Hernando, I; Nolla, JM; Perez-Ruiz, F	1
Caldas, CA; Fuller, R	1
Pascual, E; Sivera, F	1
Brouwers, JR; Houtman, PM; Jansen, TL; Reinders, MK; van Roon, EN	1
Cheng, CH; Fong, WP; Yu, Z	1
Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN	1
Fujimori, S	1
Ohno, I	1
Brouwers, JR; Delsing, J; Haagsma, C; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN	1
Bibert, S; Bonny, O; Firsov, D; Geering, K; Hess, SK; Horisberger, JD; Thorens, B	1
Anker, SD; Doehner, W; Furuse, Y; Hisatome, I; Igawa, O; Ishida, K; Kato, M; Kinugasa, Y; Kinugawa, T; Ogino, K; Osaki, S; Shigemasa, C	1
Bahrudin, U; Hamada, T; Hisatome, I; Hosoyamada, M; Ichida, K; Igawa, O; Iwai, C; Kuwabara, M; Kuwabara, N; Mizuta, E; Nindita, Y; Ninomiya, H; Shigemasa, C; Tsuchihashi, T; Urashima, S; Utami, SB; Yamada, K	1
Gonzalez-Gay, MA; Hernandez-Baldizon, S; Herrero-Beites, AM; Perez-Ruiz, F	1
Mamada, H; Nakanishi, T; Sato, M; Shirasaka, Y; Tamai, I; Wakayama, T	1
Chernichovski, T; Engel, A; Grupper, A; Hillel, O; Schwartz, D; Schwartz, IF	1
Hisatome, I	1
Anzai, N; Endou, H; Enomoto, A; Fujimura, M; Miyazaki, H; Shin, HJ; Takeda, M	1
Anzai, N; Chanluang, S; Endou, H; Fukutomi, T; He, X; Jutabha, P; Miura, D	1
Kriegsmann, J; Lange, U; Müller-Ladner, U; Panzner, I; Tausche, AK	1
Sun, WF; Xu, W; Zhang, XX	1
Johnson, RJ; Mazali, FC; Mazzali, M	1
Fujimori, S; Moromizato, H; Ooyama, H; Ooyama, K	1
Koga, M; Koyama, H; Kurajoh, M; Moriwaki, Y; Shoji, T; Sumida, C; Tsutsumi, Z; Yamamoto, A; Yamamoto, T	1
Dong, L; Huang, X; Pang, M; Wang, S; Zhou, L; Zhu, W	1
Anzai, N; Nakanishi, T; Ohya, K; Shimada, S; Tamai, I	1
Chen, YI; Huang, CS	1
Chen, GL; Li, L; Na, S; Zhu, LR	1
Joo, H; Joo, K; Jung, KH; Kwon, SR; Lim, MJ; Park, W	1
Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R	2
Chen, H; Ji, Z; Jiang, L; Ma, L; Wei, L; Yu, Q; Zhang, Z	1
Akahoshi, Y; Ikeda, M; Shinozuka, K; Tabuchi, M; Uchida, S; Wakuda, H; Yamada, S	1
Dalbeth, N; Robinson, PC	1
Chen, X; Gao, Z; Xu, H; Zhan, L; Zheng, Y; Zhou, X	1
Chuang, VT; Hirata, S; Kadowaki, D; Maruyama, T; Miyamoto, Y; Muraya, N; Narita, Y; Otagiri, M; Sakaguchi, S; Sato, K; Taguchi, K	1
Huang, Y; Zhao, J	1
Hanvivadhanakul, P; Wongdet, R	1
Gui, D; Guo, Y; Jiang, Q; Wang, N	1
Ahn, SO; Horiba, N; Kawabe, Y; Kim, BH; Kim, KH; Kiyokawa, J; Lee, KJ; Nakagawa, T; Ohtomo, S; Tanaka, J; Yamane, M	1
Anzai, N; Hamada, T; Hirota, Y; Hisatome, I; Ikeda, N; Kato, M; Kuwabara, M; Maharani, N; Mishima, M; Miyazaki, S; Mizuta, E; Ninomiya, H; Notsu, T; Ogino, K; Onohara, T; Otani, N; Sugihara, S; Yoshida, A	1
Chen, G; Jia, P	1
Cathro, A; Corkill, M; Dalbeth, N; Frampton, C; Gardner, D; Grainger, R; Haslett, J; Kain, T; Kumar, R; Kumar, S; Metcalfe, S; Porter, D; Stamp, LK; Stebbings, S; Taylor, G; White, D; Wyeth, J	1
Hifumi, A; Kojima, S; Ogawa, H; Soejima, H	1
Arima, H; Hayashi, S; Ishizuka, A; Iwashima, Y; Kawano, Y; Kishida, M; Nakamura, S; Ohta, Y; Yoshihara, F	1
Stamp, LK	1
Chen, X; Su, J; Tian, J; Zhou, Q; Zhou, T; Zhu, J	1
Chiang, SJ; Daimon, M; Ho, Y; Lin, HC; Uang, YS; Wang, CH; Wang, LH	1
Gunic, E; Liu, S; Miner, JN; Tan, PK	1
Kim, JW; Kwak, SG; Park, SH	1
Li, LY; Lin, ZJ; Nie, AZ; Wang, Y; Zhang, B	1
Chiu, HT; Chou, HW; Huang, HC; Kuo, CC; Ting, IW; Tsai, CW; Yeh, HC	1
Cai, W; Liu, W; Liu, Y; Tang, L; Wang, J; Wu, J; Xie, Y; Xu, W; Zhang, S; Zhao, G	1
Bao, H; Cheng, J; Liu, X; Peng, A; Qin, L; Song, Y; Wang, L; Yu, H; Zhou, X	1
Gillen, M; Hall, J; Ito, Y; Liu, S; Shen, Z; Shiramoto, M; Yamamoto, A; Yan, X	1
Abe, A; Anzai, N; Furihata, T; Ito, K; Kitagawara, Y; Mashino, T; Morio, H; Nakamura, S; Ohe, T; Okunushi, K; Sekine, S; Takahashi, K; Umezawa, R; Yasuda, D	1
Chang, HW; Lan, YC; Lin, MH; Lin, YW; Wang, RY	1
Bachettoni, A; Bartoli, M; Facchiano, F; Gutsaeva, DR; Malla, P; Martin, PM; Montemari, A; Powell, FL; Repossi, A; Ripandelli, G; Tawfik, A; Thounaojam, MC	1
Deng, JX; Jie, LG; Qu, Y; Wu, J; Yu, QH; Zhang, YP	1
Araujo, E; Baraf, HSB; Bayat, S; Cavallaro, A; Ellmann, H; Kleyer, A; Lell, M; Manger, B; Rech, J; Schenker, H; Schett, G; Simon, D; Tascilar, K	1
Cheng, X; Cui, L; He, Y; Ji, A; Li, C; Li, H; Liang, N; Ma, L; Sun, M; Sun, R; Sun, W; Wang, C; Wu, X; Xu, T; Xue, X; Yuan, X; Zhang, H	1
Chen, JS; Chiou, MJ; Chung, TT; Hsieh, AH; Kuo, CF; Lan, WC; Luo, SF; Tseng, WY; Wang, LC; Yu, KH	1
Gao, H	1
Kuriyama, S	1
Han, H; Li, X; Tian, J; Yan, Z; Ye, F; Zhang, X	1
Fushimi, M; Hosoya, T; Ohashi, T; Sano, T; Sasaki, T	1
Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T	1
Cao, Y; Chen, Y; Jiang, Y; Li, L; Li, Y; Pang, J; Wu, T; Zhao, Z; Zhou, P	1
Sakaguchi, S	1
Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T	1
Li, Y; Liang, D; Liang, Z; Liu, H; Liu, Y; Su, M; Sun, L; Wang, D; Wei, Y; Yin, S; Zhang, G; Zhang, S; Zhao, J	1
Ashizawa, N; Iwanaga, T; Kobashi, S; Matsumoto, K; Uda, J	1
Becce, F; Budzik, JF; Ducoulombier, V; Lefebvre, A; Pascart, T	1
Lee, YH; Song, GG	1
Chen, JS; Liu, C; Liu, YF; Sun, B; Sun, JY; Wang, CZ; Wang, MM; Wang, MX; Wang, Z; Yang, QL; Zhang, YK	1
Cai, M; Chen, S; Gao, X; Hu, H; Huang, L; Li, X; Liang, D; Liu, Y; Wu, Q; Xiao, C; Xie, Y; Yong, T	1
Chen, Y; Cheng, X; Cui, L; Dalbeth, N; He, Y; Hu, S; Ji, A; Li, C; Li, H; Liu, Z; Lu, J; Ma, L; Qi, H; Ran, Z; Sun, M; Terkeltaub, R; Wang, C; Xue, X; Yan, F; Yu, Q; Yuan, X	1
Cao, Y; Chen, J; Chen, Y; Feng, H; Guo, J; Kuang, P; Liao, H; Lin, C; Liu, J; Luo, J; Pang, J; Wu, T; Yang, Y; Yang, Z; Yuan, L; Zhang, Q; Zhao, Z; Zheng, F	1
Chang, HH; Hsieh, SM; Lin, DP; Pai, HL; Su, YS; Sue, XY	1
Iguchi, T; Ishiguro, C; Kajiyama, K; Kimura, R; Nakazato, Y; Oniyama, Y; Sawada, S; Shida, H; Uyama, Y	1
Ashizawa, N; Chikamatsu, N; Iwanaga, T; Motoki, K; Sakai, M; Taniguchi, T; Yamano, K	1
Hwang, BF; Kuo, YH; Lai, SW; Liao, KF; Liu, CS	2
Kawada, T	1
Gu, J; Han, Z; Ke, J; Lin, H; Pan, J	1
Arima, H; Funakoshi, R; Iseki, K; Ishida, A; Kinjyo, K; Kochi, M; Kohagura, K; Nakamura, T; Ohya, Y; Sakima, A; Satoh, A; Tana, T; Yamazato, M; Zamami, R	1

Reviews

16 review(s) available for uric acid and benzbromarone

Article	Year
Urate excretion. Annual review of medicine, 1977, Volume: 28 Topics: Acetohexamide; Animals; Benzbromarone; Benzofurans; Diuretics; Ethambutol; Halofenate; Humans; Mersalyl; Pan troglodytes; Probenecid; Salicylates; Sulfinpyrazone; Uric Acid; Zoxazolamine	1977
Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. Drugs, 1977, Volume: 14, Issue:5 Topics: Aspirin; Benzbromarone; Benzofurans; Drug Interactions; Fasting; Gout; Humans; Kidney Diseases; Kinetics; Lipid Metabolism; Pyrazinamide; Triglycerides; Uric Acid; Xanthine Oxidase	1977
Treatment of the gout and other forms of crystal-induced arthritis. Bulletin on the rheumatic diseases, 1982, Volume: 32, Issue:5 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Kidney; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1982
[Benzbromarone in the treatment of gout]. Reumatologia, 1980, Volume: 18, Issue:1 Topics: Benzbromarone; Benzofurans; Biological Availability; Chemical Phenomena; Chemistry; Gout; Half-Life; Humans; Time Factors; Uric Acid	1980
[Management of hyperuricemia in diabetes]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl Topics: Allopurinol; Benzbromarone; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Insulin Resistance; Probenecid; Uric Acid; Uricosuric Agents	1997
[Molecular mechanism in biological transport in the kidney: Urate transporter URAT1]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2 Topics: Animals; Benzbromarone; Carrier Proteins; Humans; Hyperuricemia; Kidney Tubules; Organic Anion Transporters; Organic Cation Transport Proteins; Probenecid; RNA, Messenger; Transcription, Genetic; Uric Acid; Uricosuric Agents	2006
[Establishment of therapeutic goal and plan of gout and asymptomatic hyperuricemia]. Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:4 Topics: Allopurinol; Benzbromarone; Cardiovascular Diseases; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Patient Care Planning; Practice Guidelines as Topic; Renal Insufficiency; Uric Acid	2008
[Uricosuric agent]. Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:4 Topics: Allopurinol; Benzbromarone; Gout; Humans; Hyperuricemia; Kidney Tubules, Proximal; Organic Anion Transporters; Organic Cation Transport Proteins; Uric Acid; Uricosuric Agents	2008
[Impact of serum uric acid level on the cardiovascular system as a risk factor]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6 Topics: Adipokines; Benzbromarone; Cardiovascular Diseases; Hyperuricemia; Kidney; Organic Anion Transporters; Organic Cation Transport Proteins; Oxidation-Reduction; Probenecid; Renal Tubular Transport, Inborn Errors; Risk Factors; Uric Acid; Uricosuric Agents; Urinary Calculi	2010
[Gout - regardless of therapeutic options a "forgotten" disease]. Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:33 Topics: Allopurinol; Arthritis, Gouty; Benzbromarone; Combined Modality Therapy; Cytokines; Europe; Febuxostat; Gout; Gout Suppressants; Guideline Adherence; Humans; Inflammasomes; Interleukin-1; Long-Term Care; Probenecid; Signal Transduction; Thiazoles; Uric Acid	2011
Allopurinol for chronic gout. The Cochrane database of systematic reviews, 2014, Oct-14, Issue:10 Topics: Allopurinol; Benzbromarone; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid	2014
Uricosuric medications for chronic gout. The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11 Topics: Adult; Aged; Allopurinol; Benzbromarone; Chronic Disease; Controlled Clinical Trials as Topic; Female; Gout; Humans; Male; Middle Aged; Probenecid; Randomized Controlled Trials as Topic; Uric Acid; Uricosuric Agents	2014
Advances in pharmacotherapy for the treatment of gout. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:4 Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzbromarone; Clinical Trials, Phase III as Topic; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Probenecid; Thiazoles; Urate Oxidase; Uric Acid	2015
Major unanswered questions in the clinical gout field. Current opinion in rheumatology, 2017, Volume: 29, Issue:2 Topics: Allopurinol; Benzbromarone; Colchicine; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Patient Care Planning; Probenecid; Renal Insufficiency, Chronic; Uric Acid; Uricosuric Agents	2017
Dotinurad: a novel selective urate reabsorption inhibitor as a future therapeutic option for hyperuricemia. Clinical and experimental nephrology, 2020, Volume: 24, Issue:Suppl 1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Benzothiazoles; Drug Interactions; Febuxostat; Female; Gout; Humans; Hyperuricemia; Male; Uric Acid; Uricosuric Agents	2020
Comparative efficacy and safety of dotinurad, febuxostat, and benzbromarone in hyperuricemic patients with or without gout: A network meta-analysis of randomized controlled trials. International journal of clinical pharmacology and therapeutics, 2022, Volume: 60, Issue:3 Topics: Benzbromarone; Benzothiazoles; Febuxostat; Gout; Gout Suppressants; Humans; Network Meta-Analysis; Randomized Controlled Trials as Topic; Treatment Outcome; Uric Acid; Uricosuric Agents	2022

Trials

43 trial(s) available for uric acid and benzbromarone

Article	Year
[Hypouricemic effect of benzbromarone especially in kidney failure]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1978, Volume: 54, Issue:9-12 Topics: Adolescent; Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Depression, Chemical; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Uric Acid	1978
[Treatment of hyperuricemia using daily doses of 50 and 25mg of benzbromarone]. Fortschritte der Medizin, 1977, Jul-21, Volume: 95, Issue:27 Topics: Benzbromarone; Clinical Trials as Topic; Drug Evaluation; Gout; Humans; Male; Uric Acid	1977
[Uric acid lowering effects of benzbromarone (Harolan) by increasing uric acid excretion]. Fortschritte der Medizin, 1979, May-03, Volume: 97, Issue:17 Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Humans; Male; Middle Aged; Uric Acid	1979
[Effect of uric acid lowering drugs in low dosage in patients with hyperuricemia and hypertriglyceridemia in a randomized group study]. Fortschritte der Medizin, 1979, Jul-19, Volume: 97, Issue:27 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Humans; Hyperlipidemias; Male; Middle Aged; Triglycerides; Uric Acid	1979
[The uricosuric effect of benzbromaron and probenecid under fasting conditions (author's transl)]. Medizinische Klinik, 1978, Feb-17, Volume: 73, Issue:7 Topics: Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Fasting; Female; Humans; Kidney Tubules; Male; p-Aminohippuric Acid; Probenecid; Uric Acid	1978
[The effect of benzbromarone on fasting-hyperuricemia as a model (author's transl)]. Medizinische Klinik, 1978, Jun-09, Volume: 73, Issue:23 Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Humans; Male; Middle Aged; Obesity; Probenecid; Purines; Uric Acid	1978
[Reducing the risks in the treatment of gout and hyperuricaemia (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1976, Aug-27, Volume: 101, Issue:35 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Drug Combinations; Female; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Uric Acid	1976
[Therapy with alllopurinol and benzbromarone, single and combined. Renal elimination of lithogenous and colloid protective substances (author's transl)]. Medizinische Klinik, 1977, Apr-15, Volume: 72, Issue:15 Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Calcium; Citrates; Creatinine; Glomerular Filtration Rate; Gout; Humans; Magnesium; Male; Middle Aged; Natriuresis; Sodium; Uric Acid	1977
[Effect of benzbromarone in 100mg and 50mg doses on healthy subjects]. Fortschritte der Medizin, 1977, Jul-21, Volume: 95, Issue:27 Topics: Administration, Oral; Analysis of Variance; Benzbromarone; Benzofurans; Humans; Male; Uric Acid	1977
[Pathogenesis and treatment of fast-induced hyperuricemia using benzbromarone]. Die Medizinische Welt, 1976, Mar-19, Volume: 27, Issue:12 Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Gout; Humans; Male; Middle Aged; Starvation; Uric Acid	1976
[Effectiveness and tolerance of long-term uricosuric treatment]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990, Dec-01, Volume: 45, Issue:23 Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Combinations; Female; Gout; Humans; Kidney Calculi; Male; Middle Aged; Uric Acid	1990
Benzbromarone disposition and uricosuric action; evidence for hydroxilation instead of debromination to benzarone. Klinische Wochenschrift, 1988, Feb-15, Volume: 66, Issue:4 Topics: Adult; Benzbromarone; Benzofurans; Humans; Hydroxylation; Inactivation, Metabolic; Male; Protein Binding; Purines; Uric Acid	1988
[Effect of benziodarone and benzbromarone on the uric acid level in the blood and urine and on the incidence of gout attacks]. Reumatologia, 1980, Volume: 18, Issue:3 Topics: Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Gout; Humans; Male; Middle Aged; Uric Acid	1980
Benzbromarone as a long-term uricosuric agent. Advances in experimental medicine and biology, 1980, Volume: 122A Topics: Benzbromarone; Benzofurans; Clinical Trials as Topic; Follow-Up Studies; Gout; Humans; Uric Acid	1980
The action of benzbromarone in relation to age, sex and accompanying diseases. Advances in experimental medicine and biology, 1980, Volume: 122A Topics: Benzbromarone; Benzofurans; Body Height; Body Weight; Clinical Trials as Topic; Female; Follow-Up Studies; Gout; Humans; Male; Uric Acid	1980
Benzbromarone therapy in hyperuricaemia. The Journal of international medical research, 1981, Volume: 9, Issue:1 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Benzbromarone; Benzofurans; Clinical Trials as Topic; Creatinine; Female; Humans; Male; Middle Aged; Uric Acid	1981
Benzbromarone therapy in hyperuricaemia; comparison with allopurinol and probenecid. The Journal of international medical research, 1981, Volume: 9, Issue:6 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Female; Humans; Male; Placebos; Probenecid; Uric Acid	1981
[The effect on uric acid and other laboratory parameters. A long-term study]. ZFA. Zeitschrift fur Allgemeinmedizin, 1982, Feb-20, Volume: 58, Issue:5 Topics: Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Gout; Humans; Uric Acid	1982
[Prevention of urinary calculi by means of a benzbromarone-citrate combination]. Fortschritte der Medizin, 1980, Nov-27, Volume: 98, Issue:44 Topics: Adult; Aged; Benzbromarone; Benzofurans; Circadian Rhythm; Citrates; Drug Combinations; Humans; Hydrogen-Ion Concentration; Middle Aged; Uric Acid; Urinary Calculi	1980
The effect of benzbromarone on allopurinol/oxypurinol kinetics in patients with gout. European journal of clinical pharmacology, 1993, Volume: 44, Issue:1 Topics: Adult; Aged; Allopurinol; Benzbromarone; Gout; Humans; Male; Middle Aged; Oxypurinol; Uric Acid	1993
Effect of allopurinol and benzbromarone on the concentration of uridine in plasma. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Topics: Adult; Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Gout; Gout Suppressants; Humans; Male; Middle Aged; Purines; Pyrimidines; Time Factors; Uric Acid; Uricosuric Agents; Uridine; Xanthine Oxidase	1997
Efficacy of allopurinol and benzbromarone for the control of hyperuricaemia. A pathogenic approach to the treatment of primary chronic gout. Annals of the rheumatic diseases, 1998, Volume: 57, Issue:9 Topics: Adult; Aged; Allopurinol; Benzbromarone; Chronic Disease; Drug Administration Schedule; Gout; Gout Suppressants; Humans; Male; Middle Aged; Prospective Studies; Uric Acid; Uricosuric Agents	1998
Does a relationship exist between the urate pool in the body and lipid peroxidation during exercise? Free radical research, 2000, Volume: 32, Issue:1 Topics: Adult; Allantoin; Ascorbic Acid; Benzbromarone; Case-Control Studies; Exercise; Humans; Inosine Monophosphate; Lactates; Lipid Peroxidation; Male; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Uric Acid; Uricosuric Agents; Vitamin E	2000
Improvement of renal function in patients with chronic gout after proper control of hyperuricemia and gouty bouts. Nephron, 2000, Volume: 86, Issue:3 Topics: Adult; Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Creatinine; Drug Therapy, Combination; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency; Risk Factors; Uric Acid; Uricosuric Agents	2000
Efficacy of benzbromarone compared to allopurinol in lowering serum uric acid level in hyperuricemic patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85 Suppl 1 Topics: Adult; Aged; Allopurinol; Benzbromarone; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gout; Humans; Male; Middle Aged; Probability; Statistics, Nonparametric; Treatment Outcome; Uric Acid; Uricosuric Agents; Urinalysis	2002
Effect of urate-lowering therapy on the velocity of size reduction of tophi in chronic gout. Arthritis and rheumatism, 2002, Volume: 47, Issue:4 Topics: Adult; Aged; Allopurinol; Benzbromarone; Crystallization; Drug Therapy, Combination; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Prospective Studies; Uric Acid	2002
Benzbromarone therapy in management of refractory gout. The New Zealand medical journal, 2005, Jun-24, Volume: 118, Issue:1217 Topics: Adult; Allopurinol; Benzbromarone; Creatinine; Female; Gout; Humans; Incidence; Male; Metabolic Clearance Rate; Middle Aged; New Zealand; Treatment Outcome; Uric Acid	2005
Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients. Clinical rheumatology, 2007, Volume: 26, Issue:9 Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid; Uric Acid; Uricosuric Agents	2007
Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:1 Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Prospective Studies; Treatment Failure; Uric Acid	2009
A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:6 Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Oxypurinol; Patient Compliance; Prospective Studies; Treatment Outcome; Uric Acid; Uricosuric Agents	2009
Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study. Circulation. Heart failure, 2010, Volume: 3, Issue:1 Topics: Aged; Benzbromarone; Double-Blind Method; Female; Heart Failure; Humans; Hyperuricemia; Male; Middle Aged; Treatment Outcome; Up-Regulation; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2010
[Assessment on the clinical efficacy and safety of xiezhuo chubi recipe in treating hyperuricemia]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2011, Volume: 31, Issue:9 Topics: Adolescent; Adult; Aged; Benzbromarone; Drugs, Chinese Herbal; Female; Humans; Hyperuricemia; Male; Middle Aged; Phytotherapy; Treatment Outcome; Uric Acid; Young Adult	2011
Therapeutic strategy for efficient reduction of serum uric acid levels with allopurinol versus benzbromarone in hyperuricemic patients with essential hypertension - A randomized crossover study (terao study). International journal of cardiology, 2016, Dec-01, Volume: 224 Topics: Aged; Aged, 80 and over; Allopurinol; Benzbromarone; Drug Administration Schedule; Drug Monitoring; Enzyme Inhibitors; Essential Hypertension; Female; Humans; Hypertension; Hyperuricemia; Kidney Function Tests; Male; Middle Aged; Organic Anion Transporters; Stroke Volume; Treatment Outcome; Uric Acid; Xanthine Oxidase	2016
Effective uric acid-lowering treatment for hypertensive patients with hyperuricemia. Hypertension research : official journal of the Japanese Society of Hypertension, 2017, Volume: 40, Issue:3 Topics: Aged; Benzbromarone; Cross-Over Studies; Drug Therapy, Combination; Febuxostat; Female; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Treatment Outcome; Uric Acid	2017
Allopurinol, benzbromarone and risk of coronary heart disease in gout patients: A population-based study. International journal of cardiology, 2017, Apr-15, Volume: 233 Topics: Allopurinol; Benzbromarone; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gout; Gout Suppressants; Humans; Incidence; Male; Middle Aged; Population Surveillance; Risk Factors; Taiwan; Treatment Outcome; Uric Acid; Uricosuric Agents	2017
Safety and Efficacy of Benzbromarone and Febuxostat in Hyperuricemia Patients with Chronic Kidney Disease: A Prospective Pilot Study. Clinical and experimental nephrology, 2018, Volume: 22, Issue:6 Topics: Aged; Alpha-Globulins; Benzbromarone; Febuxostat; Female; Glomerular Filtration Rate; Hemoglobins; Humans; Hyperuricemia; Kidney Calculi; Male; Middle Aged; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Uric Acid; Uricosuric Agents	2018
Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study. Rheumatology (Oxford, England), 2018, 09-01, Volume: 57, Issue:9 Topics: Administration, Oral; Adult; Aged; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Time Factors; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Young Adult	2018
Baseline urate level and renal function predict outcomes of urate-lowering therapy using low doses of febuxostat and benzbromarone: a prospective, randomized controlled study in a Chinese primary gout cohort. Arthritis research & therapy, 2019, 09-02, Volume: 21, Issue:1 Topics: Benzbromarone; Biomarkers; China; Dose-Response Relationship, Drug; Febuxostat; Follow-Up Studies; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Kidney; Male; Middle Aged; Prospective Studies; Treatment Outcome; Uric Acid; Uricosuric Agents	2019
Dotinurad versus benzbromarone in Japanese hyperuricemic patient with or without gout: a randomized, double-blind, parallel-group, phase 3 study. Clinical and experimental nephrology, 2020, Volume: 24, Issue:Suppl 1 Topics: Adult; Aged; Benzbromarone; Benzothiazoles; Double-Blind Method; Female; Gout; Humans; Hyperuricemia; Japan; Male; Middle Aged; Treatment Outcome; Uric Acid; Uricosuric Agents	2020
Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. International heart journal, 2020, Sep-29, Volume: 61, Issue:5 Topics: Adiponectin; Aged; Arginine; Benzbromarone; Cross-Over Studies; Endothelium, Vascular; Febuxostat; Female; Gout Suppressants; Humans; Hyperemia; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Treatment Outcome; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2020
Superiority of Low-Dose Benzbromarone to Low-Dose Febuxostat in a Prospective, Randomized Comparative Effectiveness Trial in Gout Patients With Renal Uric Acid Underexcretion. Arthritis & rheumatology (Hoboken, N.J.), 2022, Volume: 74, Issue:12 Topics: Allopurinol; Benzbromarone; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Prospective Studies; Treatment Outcome; Uric Acid	2022
Uric acid-lowering therapy with benzbromarone in hypertension with asymptomatic hyperuricemia: a randomized study focusing left ventricular diastolic function. Current medical research and opinion, 2023, Volume: 39, Issue:7 Topics: Benzbromarone; Heart Failure; Humans; Hypertension; Hyperuricemia; Stroke Volume; Uric Acid	2023
Urate-lowering drugs for chronic kidney disease with asymptomatic hyperuricemia and hypertension: a randomized trial. Journal of hypertension, 2023, 09-01, Volume: 41, Issue:9 Topics: Benzbromarone; Febuxostat; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Renal Insufficiency, Chronic; Treatment Outcome; Uric Acid	2023

Other Studies

149 other study(ies) available for uric acid and benzbromarone

Article	Year
Urate transport via human PAH transporter hOAT1 and its gene structure. Kidney international, 2003, Volume: 63, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Biological Transport; Blotting, Western; Carbon Radioisotopes; Cell Line; Cloning, Molecular; Exons; Female; Gene Library; Gout; Humans; Kidney; Kidney Diseases; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Probenecid; Protein Structure, Tertiary; Pyrazinamide; Sodium Salicylate; Uric Acid; Uricosuric Agents	2003
Discovery of Dotinurad (FYU-981), a New Phenol Derivative with Highly Potent Uric Acid Lowering Activity. ACS medicinal chemistry letters, 2020, Oct-08, Volume: 11, Issue:10 Topics:	2020
[The uric acid-lowering action of benzbromarone effervescent granules and allopurinol. Comparative studies (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1978, Oct-20, Volume: 120, Issue:42 Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Dosage Forms; Female; Humans; Male; Middle Aged; Uric Acid; Uricosuric Agents	1978
[The treatment of hyperuricemia after kidney transplantation]. Schweizerische medizinische Wochenschrift, 1977, Sep-24, Volume: 107, Issue:38 Topics: Allopurinol; Azathioprine; Benzbromarone; Creatinine; Drug Interactions; Female; Humans; Kidney Transplantation; Male; Transplantation, Homologous; Uric Acid; Urinary Calculi	1977
[Therapy of gout]. Fortschritte der Medizin, 1979, Aug-23, Volume: 97, Issue:32 Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Colchicine; Gout; Humans; Immobilization; Indomethacin; Uric Acid	1979
[The effect of benzbromaron in gout patients with limited kidney function]. Fortschritte der Medizin, 1979, Nov-22, Volume: 97, Issue:44 Topics: Adult; Aged; Benzbromarone; Benzofurans; Creatinine; Drug Evaluation; Gout; Humans; Kidney Diseases; Male; Middle Aged; Uric Acid	1979
[Allomaron in hyperuricemia and gout]. ZFA. Zeitschrift fur Allgemeinmedizin, 1979, Aug-31, Volume: 55, Issue:24 Topics: Adolescent; Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Drug Evaluation; Female; Gout; Humans; Male; Middle Aged; Uric Acid	1979
[Comparative study of uric acid concentration in serum and saliva of healthy or hyperuricemic subjects]. Annales de biologie clinique, 1977, Volume: 35, Issue:6 Topics: Benzbromarone; Benzofurans; Humans; Methods; Saliva; Uric Acid	1977
[Effects and side effects of benzbromaron in the initial treatment of hyperuricemia and gout. Results of a field study on 3899 patients]. Fortschritte der Medizin, 1978, Aug-24, Volume: 96, Issue:32 Topics: Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Kidney Calculi; Male; Nausea; Uric Acid	1978
[Gout - a surgical problem]. Handchirurgie, 1978, Volume: 10, Issue:1 Topics: Allopurinol; Benzbromarone; Female; Gout; Hand; Humans; Middle Aged; Patient Care Team; Uric Acid	1978
Treatment of gout with alternate-day hypo-uricaemic drugs. Rheumatology and rehabilitation, 1978, Volume: 17, Issue:3 Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Gout; Humans; Male; Middle Aged; Sulfinpyrazone; Uric Acid	1978
[Long-term therapy with benzbromarone in uric arthritis]. Wiener medizinische Wochenschrift (1946), 1975, Sep-19, Volume: 125, Issue:28 Topics: Adult; Aged; Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Leukopenia; Long-Term Care; Male; Middle Aged; Uric Acid	1975
Protein binding to monosodium urate crystals and its effect on platelet degranulation. Influence of urate on connective tissue metabolism. Advances in experimental medicine and biology, 1977, Volume: 76B Topics: Acetylglucosaminidase; Benzbromarone; Connective Tissue; Glycosaminoglycans; Gout; Heparin; Hyaluronoglucosaminidase; Lysosomes; Models, Biological; Proteoglycans; Solubility; Synovial Fluid; Uric Acid	1977
The pharmacology of the hypouricemic effect of benzbromarone. Advances in experimental medicine and biology, 1977, Volume: 76B Topics: Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Drug Interactions; Glomerular Filtration Rate; Kidney Tubules; Protein Binding; Pyrazinamide; Sulfinpyrazone; Uric Acid; Xanthine Oxidase	1977
[Mechanisms of action of benzbromarone. Study in 3 anephric subjects. Preliminary results in 3 cases]. Semaine des hopitaux. Therapeutique, 1977, Volume: 53, Issue:4 Topics: Adult; Benzbromarone; Benzofurans; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Nephrectomy; Polycystic Kidney Diseases; Proteinuria; Pyelonephritis; Renal Dialysis; Uric Acid	1977
[Isolated or combined drug therapy of hyperuricemia?]. Deutsche medizinische Wochenschrift (1946), 1977, Jul-29, Volume: 102, Issue:30 Topics: Allopurinol; Benzbromarone; Drug Therapy, Combination; Gout; Humans; Uric Acid; Uricosuric Agents	1977
[Action of benzbromarone on the renal excretion of allantoin in normouricemic and hyperuricemic humans (author's transl)]. Klinische Wochenschrift, 1977, Nov-01, Volume: 55, Issue:21 Topics: Adult; Allantoin; Benzbromarone; Benzofurans; Female; Humans; Male; Uric Acid; Uricosuric Agents	1977
[Serum uric acid and uric acid elimination after benzbromarone therapy in patients with gout and hyperuricemia]. Fortschritte der Medizin, 1976, Sep-16, Volume: 94, Issue:26 Topics: Benzbromarone; Benzofurans; Gout; Humans; Uric Acid	1976
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. The Journal of rheumatology, 1976, Volume: 3, Issue:3 Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; Gout; Humans; Hydrochlorothiazide; Kinetics; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid	1976
[Treatment of hyperuricaemia with a combination of allopurinol and benzbromaron (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1976, Oct-22, Volume: 101, Issue:43 Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Gout; Humans; Time Factors; Uric Acid	1976
The pharmacology of hypouricemic effect of benzbromarone. The Journal of rheumatology, 1975, Volume: 2, Issue:4 Topics: Adult; Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Creatinine; Female; Gout; Humans; Male; Middle Aged; Protein Binding; Pyrazinamide; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1975
[Which uric acid value is in need of treatment?]. Schweizerische medizinische Wochenschrift, 1976, Apr-03, Volume: 106, Issue:14 Topics: Allopurinol; Benzbromarone; Citrates; Coronary Disease; Gout; Humans; Hyperlipidemias; Hypertension; Hypoxanthine Phosphoribosyltransferase; Kidney Diseases; Lesch-Nyhan Syndrome; Obesity; Uric Acid	1976
Circadian rhythm of plasma uric acid and handling stress-induced hyperuricemia in conscious cebus monkeys. Japanese journal of pharmacology, 1992, Volume: 58, Issue:4 Topics: Animals; Benzbromarone; Cebus; Circadian Rhythm; Diazepam; Female; Gum Arabic; Handling, Psychological; Male; Probenecid; Stress, Physiological; Uric Acid	1992
[Long lasting normalization of uric acid after combination therapy with 300 mg allopurinol and 60 mg benzbromarone in patients with gout and hyperuricemia]. Medizinische Klinik (Munich, Germany : 1983), 1992, Sep-15, Volume: 87, Issue:9 Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gout; Humans; Male; Uric Acid	1992
Two cases in whom pyrazinamide does not inhibit the uricosuric action of benzbromarone. Nephron, 1992, Volume: 61, Issue:4 Topics: Adult; Benzbromarone; Diabetes Mellitus, Type 2; Drug Interactions; Female; Humans; Kidney; Kidney Diseases; Male; Pyrazinamide; Uric Acid	1992
Changes caused by ethanol intake on metabolism of hypouricemic agents (combination of allopurinol and benzbromarone). Advances in experimental medicine and biology, 1991, Volume: 309A Topics: Adult; Alcohol Drinking; Allopurinol; Benzbromarone; Ethanol; Humans; Male; Middle Aged; Time Factors; Uric Acid	1991
Pharmacokinetics of benzbromarone: evidence for a biliary-intestinal-biliary recirculation. Advances in experimental medicine and biology, 1991, Volume: 309A Topics: Benzbromarone; Bile; Chromatography, High Pressure Liquid; Humans; Intestines; Uric Acid	1991
Analysis of uric acid transport in renal tubules using benzbromarone and pyrazinamide. Advances in experimental medicine and biology, 1991, Volume: 309A Topics: Absorption; Adult; Benzbromarone; Humans; Kidney Tubules; Male; Middle Aged; Models, Biological; Pyrazinamide; Uric Acid	1991
[Uric acid and arterial hypertension. II. Evaluation of uric acid transport in the nephrons in primary arterial hypertension]. Polskie Archiwum Medycyny Wewnetrznej, 1991, Volume: 86, Issue:3 Topics: Adult; Benzbromarone; Biological Transport; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Function Tests; Kidney Glomerulus; Kidney Tubules; Male; Middle Aged; Pyrazinamide; Uric Acid	1991
[Uric acid level in blood donors of southern Germany--almost constant since 1971]. Fortschritte der Medizin, 1991, Jul-30, Volume: 109, Issue:22 Topics: Adult; Arthritis, Gouty; Benzbromarone; Benzimidazoles; Blood Donors; Cross-Sectional Studies; Female; Germany; Gout; Humans; Incidence; Male; Uric Acid; Uricosuric Agents	1991
Acute uric acid nephropathy in two gouty patients with moderate hyperuricemia and high urine acidity. Klinische Wochenschrift, 1990, Sep-03, Volume: 68, Issue:17 Topics: Acute Kidney Injury; Benzbromarone; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Uric Acid	1990
[Clinical studies on hyperuricemia and gout after transplantation]. Hinyokika kiyo. Acta urologica Japonica, 1990, Volume: 36, Issue:8 Topics: Adult; Allopurinol; Analgesics; Benzbromarone; Female; Gout; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Uric Acid	1990
The influence of benzbromarone and its combination with hydrochlorothiazide on renal excretion of uric acid and electrolytes. International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:10 Topics: Administration, Oral; Adult; Benzbromarone; Female; Humans; Hydrochlorothiazide; Male; Metabolic Clearance Rate; Potassium; Sodium; Time Factors; Uric Acid	1990
Analysis of uric acid transport in renal tubules using benzbromarone and pyrazinamide. International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:2 Topics: Benzbromarone; Benzofurans; Glomerular Filtration Rate; Humans; Kidney Tubules; Male; Pyrazinamide; Uric Acid	1990
[Effect of exercise on urate excretion]. Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1989, Volume: 51, Issue:7 Topics: Adult; Benzbromarone; Depression, Chemical; Exercise; Glomerular Filtration Rate; Humans; Kidney; Male; Probenecid; Pyrazinamide; Uric Acid	1989
Cause of persistent hypouricemia in outpatients. Nephron, 1989, Volume: 51, Issue:1 Topics: Benzbromarone; Female; Hematuria; Humans; Male; Outpatients; Patients; Pyrazinamide; Uric Acid	1989
Inhibition of purine catabolism by benzbromarone in isolated rat liver cells. Comparison with allopurinol and probenecid. Biochemical pharmacology, 1988, Oct-01, Volume: 37, Issue:19 Topics: Allopurinol; Animals; Benzbromarone; Benzofurans; In Vitro Techniques; Liver; Male; Probenecid; Purines; Rats; Rats, Inbred Strains; Uric Acid	1988
Renal excretion of purine bases. Effects of probenecid, benzbromarone and pyrazinamide. Nephron, 1988, Volume: 48, Issue:2 Topics: Adult; Benzbromarone; Benzofurans; Biological Transport, Active; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Male; Probenecid; Purines; Pyrazinamide; Uric Acid; Xanthine; Xanthines	1988
Renal hypouricemia due to an isolated renal defect of urate transport. Nephron, 1988, Volume: 49, Issue:1 Topics: Adult; Benzbromarone; Humans; Kidney; Kidney Diseases; Male; Pyrazinamide; Uric Acid	1988
[Effect of an allopurinol/benzbromaron preparation on the composition of urine in a circadian course]. Klinische Wochenschrift, 1987, Mar-02, Volume: 65, Issue:5 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Calcium Oxalate; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Male; Uric Acid	1987
Drug interactions with urate excretion in man. European journal of clinical pharmacology, 1987, Volume: 32, Issue:5 Topics: Adult; Ampicillin; Benzbromarone; Benzofurans; Drug Interactions; Humans; Kidney; Kinetics; Male; Probenecid; Pyrazinamide; Uric Acid	1987
[The effect of benzbromarone and its combination with hydrochlorothiazide on the renal excretion of uric acid and electrolytes]. Casopis lekaru ceskych, 1986, Aug-22, Volume: 125, Issue:34 Topics: Adult; Benzbromarone; Benzofurans; Female; Humans; Hydrochlorothiazide; Kidney; Male; Potassium; Sodium; Uric Acid	1986
Kinetics of allopurinol and oxipurinol after chronic oral administration. Interaction with benzbromarone. European journal of clinical pharmacology, 1986, Volume: 31, Issue:1 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Oxypurinol; Pyrimidines; Uric Acid	1986
Hereditary renal hypouricemia in children. The Journal of pediatrics, 1985, Volume: 107, Issue:1 Topics: Benzbromarone; Child; Child, Preschool; Creatinine; Humans; Kidney Diseases; Kidney Tubules; Metabolic Clearance Rate; Pyrazinamide; Uric Acid	1985
Does benzbromarone in therapeutic doses raise renal excretion of oxipurinol? Klinische Wochenschrift, 1984, Dec-17, Volume: 62, Issue:24 Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Therapy, Combination; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Oxypurinol; Pyrimidines; Uric Acid	1984
[Uric acid-lowering effect of a combination of benzbromarone and allopurinol--studies under standardized dietary conditions]. Arzneimittel-Forschung, 1983, Volume: 33, Issue:12 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Depression, Chemical; Diet; Erythrocytes; Female; Humans; Kidney; Male; Orotic Acid; Time Factors; Uric Acid	1983
[A case of familial renal hypouricemia associated with bladder cancer]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1984, Volume: 75, Issue:2 Topics: Aged; Benzbromarone; Carcinoma, Transitional Cell; Humans; Male; Probenecid; Pyrazinamide; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Bladder Neoplasms	1984
[Pharmacotherapeutical action on arteriosclerotic vascular diseases with benzarone (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1980, Feb-22, Volume: 122, Issue:8 Topics: Arteriosclerosis; Benzbromarone; Benzofurans; Cholesterol; Factor VIII; Humans; Intermittent Claudication; Male; Middle Aged; Plasminogen; Triglycerides; Uric Acid	1980
[Current therapy: combined drug therapy of hyperuricemia, gout and alcohol induced fatty liver]. Fortschritte der Medizin, 1983, May-12, Volume: 101, Issue:18 Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Therapy, Combination; Fatty Liver, Alcoholic; Gout; Humans; Hypoxanthine; Hypoxanthines; Uric Acid; Xanthine; Xanthines	1983
[Variations in fecal elimination of uric acid in 8 patients treated with benzbromarone]. LARC medical, 1983, Volume: 3, Issue:3 Topics: Adult; Benzbromarone; Benzofurans; Feces; Humans; Middle Aged; Uric Acid	1983
[Therapy of hyperuricemia and gout. Effect of a combination therapy of allopurinol with benzbromarone]. Fortschritte der Medizin, 1983, May-26, Volume: 101, Issue:20 Topics: Allopurinol; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Gout; Humans; Uric Acid	1983
Hypouricemia due to renal urate wasting. Two types of tubular transport defect. Nephron, 1982, Volume: 30, Issue:1 Topics: Adult; Benzbromarone; Biological Transport; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney Tubules, Proximal; Middle Aged; Pyrazinamide; Uric Acid	1982
[Treatment of hyperuricemia]. Medizinische Klinik, 1981, Feb-27, Volume: 76, Issue:5 Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Uric Acid	1981
Ten years' experience with benzbromarone in the management of gout and hyperuricaemia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, May-09, Volume: 59, Issue:20 Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Follow-Up Studies; Gout; Humans; Male; Middle Aged; Time Factors; Uric Acid	1981
[Uric acid-induced diseases. 2. Therapy]. Fortschritte der Medizin, 1980, Apr-10, Volume: 98, Issue:14 Topics: Allopurinol; Benzbromarone; Benzothiadiazines; Diuretics; Gout; Humans; Purines; Sodium Chloride Symporter Inhibitors; Uric Acid; Urinary Calculi	1980
Renal handling of uric acid in normal and gouty subject: evidence for a 4-component system. Annals of the rheumatic diseases, 1980, Volume: 39, Issue:2 Topics: Absorption; Benzbromarone; Blood Proteins; Female; Gout; Humans; In Vitro Techniques; Kidney; Kidney Tubules; Male; Models, Biological; Protein Binding; Pyrazinamide; Secretory Rate; Temperature; Uric Acid	1980
Isolated defect in postsecretory reabsorption of uric acid. Annals of the rheumatic diseases, 1980, Volume: 39, Issue:2 Topics: Absorption; Adult; Benzbromarone; Female; Humans; Metabolic Diseases; Pyrazinamide; Uric Acid	1980
[Efficacy and tolerance of a new benzbromarone preparation]. Die Medizinische Welt, 1980, May-23, Volume: 31, Issue:21 Topics: Benzbromarone; Benzofurans; Gout; Humans; Hydrogen-Ion Concentration; Uric Acid; Urine	1980
Determination of tubular secretion of urate in healthy and gouty men. Advances in experimental medicine and biology, 1980, Volume: 122A Topics: Adult; Benzbromarone; Female; Gout; Humans; Kidney Tubules; Male; Reference Values; Uric Acid	1980
[Mechanism of fasting hyperuricemia]. Revue du rhumatisme et des maladies osteo-articulaires, 1980, Volume: 47, Issue:11 Topics: Adolescent; Adult; Aged; Benzbromarone; Fasting; Female; Humans; Kidney; Male; Middle Aged; Nucleic Acids; Uric Acid	1980
[Clinical followup of the uricosuric drug--benzbromaron (author's transl)]. Bratislavske lekarske listy, 1980, Volume: 74, Issue:5 Topics: Benzbromarone; Benzofurans; Humans; Uric Acid	1980
[Erythrocyte uric acid in the non-gouty subject]. Revue du rhumatisme et des maladies osteo-articulaires, 1980, Volume: 47, Issue:12 Topics: Benzbromarone; Erythrocytes; Humans; Obesity; Renal Dialysis; Uric Acid	1980
Benzbromarone and fenofibrate are lipid lowering and uricosuric: a possible key to metabolic syndrome? Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Benzbromarone; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Fenofibrate; Gout; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney; Kinetics; Syndrome; Uric Acid; Uricosuric Agents	1994
Pharmacologic evaluation of the renal handling of uric acid and oxypurines. Nihon Jinzo Gakkai shi, 1994, Volume: 36, Issue:11 Topics: Adult; Benzbromarone; Biological Transport; Humans; Hypoxanthine; Hypoxanthines; Kidney Tubules; Male; Probenecid; Pyrazinamide; Uric Acid; Xanthines	1994
Renal hypouricemia: incomplete combined defect. Nihon Jinzo Gakkai shi, 1994, Volume: 36, Issue:8 Topics: Adult; Benzbromarone; Calcium; Humans; Male; Nephrosis, Lipoid; Probenecid; Pyrazinamide; Uric Acid	1994
Excellent uricosuric efficacy of benzbromarone in cyclosporin-A-treated renal transplant patients: a prospective study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:5 Topics: Benzbromarone; Creatinine; Cyclosporine; Drug Interactions; Female; Graft Survival; Humans; Kidney Function Tests; Kidney Transplantation; Male; Prospective Studies; Uric Acid	1994
[The use of Allomaron in treating hyperuricemia]. Terapevticheskii arkhiv, 1994, Volume: 66, Issue:1 Topics: Adult; Allopurinol; Arthritis, Gouty; Benzbromarone; Creatinine; Drug Combinations; Drug Evaluation; Female; Gout; Humans; Male; Middle Aged; Time Factors; Uric Acid	1994
[Evaluation of uric acid transport in nephrons of patients with calcium nephrolithiasis and hyperuricosuria]. Polskie Archiwum Medycyny Wewnetrznej, 1993, Volume: 90, Issue:1 Topics: Absorption; Adult; Benzbromarone; Calcium; Female; Humans; Kidney Calculi; Male; Middle Aged; Nephrons; Pyrazinamide; Recurrence; Uric Acid	1993
Renal hypouricemia due to enhanced tubular secretion of urate associated with urolithiasis: successful treatment of urolithiasis by alkalization of urine K+, Na(+)-citrate. Nephron, 1993, Volume: 65, Issue:4 Topics: Benzbromarone; Citrates; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Kidney Tubules; Middle Aged; Probenecid; Pyrazinamide; Uric Acid; Urinary Calculi	1993
Benzbromarone hydroxylation in man: defective formation of the 6-hydroxybenzbromarone metabolite. The Clinical investigator, 1993, Volume: 71, Issue:11 Topics: Administration, Oral; Adult; Benzbromarone; Diet; Female; Humans; Hydroxylation; Male; Phenotype; Uric Acid	1993
[A study on uric acid excretion in patients with hypouricemia]. Nihon Jinzo Gakkai shi, 1993, Volume: 35, Issue:7 Topics: Acute Kidney Injury; Benzbromarone; Diabetes Complications; Diabetes Mellitus; Female; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Pyrazinamide; Uric Acid	1993
Renal handling of urate in a patient with familial juvenile gouty nephropathy. Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:7 Topics: Adolescent; Benzbromarone; Female; Genes, Dominant; Gout; Gout Suppressants; Humans; Kidney; Kidney Failure, Chronic; Male; Pedigree; Probenecid; Pyrazinamide; Renal Agents; Uric Acid; Uricosuric Agents	1996
Uric acid transport in fanconi syndrome with marked renal hypouricemia: analysis using pyrazinamide and benzbromarone. Nephron, 1996, Volume: 74, Issue:2 Topics: Adolescent; Benzbromarone; Fanconi Syndrome; Humans; Kidney; Male; Pyrazinamide; Time Factors; Uric Acid; Uricosuric Agents	1996
Effects of uricosuric and antiuricosuric agents on urate transport in human brush-border membrane vesicles. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: Aged; Benzbromarone; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Diuretics; Ethambutol; Humans; Imidazoles; Kidney Cortex; Kidney Neoplasms; Kinetics; Losartan; Microvilli; Middle Aged; Probenecid; Pyrazinamide; Salicylates; Salicylic Acid; Sulfinpyrazone; Tetrazoles; Ticrynafen; Uric Acid; Uricosuric Agents	1997
Two cases of renal hypouricemia with nephrolithiasis. Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:3 Topics: Adult; Benzbromarone; Creatinine; Humans; Kidney Calculi; Kidney Tubules; Male; Middle Aged; Pyrazinamide; Uric Acid; Uricosuric Agents	1997
Gout due to xanthine derivatives. British journal of rheumatology, 1997, Volume: 36, Issue:10 Topics: Allopurinol; Aminophylline; Asthma; Benzbromarone; Bronchodilator Agents; Drug Therapy, Combination; Female; Gout; Humans; Middle Aged; Probenecid; Theophylline; Uric Acid; Uricosuric Agents	1997
Biotransformation and uric acid lowering effect of benzbromarone in patients with liver cirrhosis - evidence for active benzbromarone metabolites? European journal of medical research, 1995, Oct-16, Volume: 1, Issue:1 Topics: Adult; Benzbromarone; Female; Humans; Liver Cirrhosis; Middle Aged; Uric Acid; Uricosuric Agents	1995
Decreased serum concentrations of 1,25(OH)2-vitamin D3 in patients with gout. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:3 Topics: Adult; Allopurinol; Benzbromarone; Calcifediol; Calcitriol; Calcium; Gout; Gout Suppressants; Humans; Male; Middle Aged; Parathyroid Hormone; Phosphates; Reference Values; Uric Acid; Uricosuric Agents	1998
Hematuria in patients with renal hypouricemia. Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Benzbromarone; Creatinine; Female; Hematuria; Humans; Kidney Diseases; Male; Metabolism, Inborn Errors; Middle Aged; Probenecid; Pyrazinamide; Renal Agents; Uric Acid	1998
How should we treat tophaceous gout in patients with allopurinol hypersensitivity? Advances in experimental medicine and biology, 1998, Volume: 431 Topics: Adolescent; Adult; Aged; Allopurinol; Benzbromarone; Creatinine; Drug Hypersensitivity; Gout; Gout Suppressants; Humans; Hypoxanthine Phosphoribosyltransferase; Kidney Failure, Chronic; Male; Middle Aged; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid	1998
Apoptosis of tubular epithelial cells in familial juvenile gouty nephropathy. Nephron, 1998, Volume: 79, Issue:3 Topics: Adult; Apoptosis; Benzbromarone; Biopsy; Biotin; Deoxyuracil Nucleotides; DNA Fragmentation; Family Health; Female; Genes, Dominant; Glomerulosclerosis, Focal Segmental; Gout; Humans; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; Middle Aged; Pedigree; Probenecid; Staining and Labeling; Uremia; Uric Acid; Uricosuric Agents	1998
Restoration of the uricosuric effect of probenecid after triglycylvasopressine administration in a gouty patient. Clinical nephrology, 1998, Volume: 50, Issue:4 Topics: Absorption; Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Benzbromarone; Fludrocortisone; Gout; Humans; Kidney Tubules; Lypressin; Male; Probenecid; Pyrazinamide; Receptors, Vasopressin; Renal Agents; Terlipressin; Uric Acid; Uricosuric Agents	1998
[Gout: physiopathology, diagnosis, course, treatment]. La Revue du praticien, 1998, Sep-01, Volume: 48, Issue:13 Topics: Adult; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Diagnosis, Differential; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Synovial Fluid; Uric Acid; Uricosuric Agents	1998
A case of exercise-induced acute renal failure in a patient with enhanced renal hypouricaemia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:1 Topics: Acute Kidney Injury; Adult; Benzbromarone; Exercise; Humans; Male; Pyrazinamide; Renal Tubular Transport, Inborn Errors; Uric Acid; Uricosuric Agents	2000
[Hyperuricemia and gout--treatment]. Deutsche medizinische Wochenschrift (1946), 2002, Feb-01, Volume: 127, Issue:5 Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug Therapy, Combination; Glucocorticoids; Gout; Gout Suppressants; Humans; Kidney Calculi; Kidney Diseases; Probenecid; Time Factors; Uric Acid; Uricosuric Agents	2002
Fulminant hepatic failure associated with benzbromarone treatment: a case report. Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:5 Topics: Benzbromarone; Female; Humans; Liver Failure; Middle Aged; Uric Acid; Uricosuric Agents	2002
A case of exercise-induced acute renal failure in a patient with idiopathic renal hypouricemia developed during antihypertensive therapy with losartan and trichlormethiazide. Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:6 Topics: Acute Kidney Injury; Antihypertensive Agents; Benzbromarone; Blood Cell Count; Creatinine; Diuretics; Drug Therapy, Combination; Exercise; Humans; Hypertension; Kidney; Kidney Function Tests; Losartan; Male; Martial Arts; Middle Aged; Pyrazinamide; Sodium Chloride Symporter Inhibitors; Trichlormethiazide; Uric Acid	2003
The efficacy of combined low dose of Allopurinol and benzbromarone compared to standard dose of Allopurinol in hyperuricemia. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87, Issue:9 Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Prospective Studies; Treatment Outcome; Uric Acid; Uricosuric Agents	2004
Optimal management of chronic gout: attempting to render the (t)issues crystal-clear. The New Zealand medical journal, 2005, Jun-24, Volume: 118, Issue:1217 Topics: Allopurinol; Anti-Inflammatory Agents; Benzbromarone; Chronic Disease; Colchicine; Drug Hypersensitivity; Gout; Humans; Uric Acid; Uricosuric Agents	2005
Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone. Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:12 Topics: Animals; Benzbromarone; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Humans; Kidney; Metabolic Clearance Rate; Organic Anion Transporters; Organic Cation Transport Proteins; Oxypurinol; Solute Carrier Family 22 Member 5; Symporters; Uric Acid; Uricosuric Agents; Xenopus laevis	2005
Using serum urate levels to determine the period free of gouty symptoms after withdrawal of long-term urate-lowering therapy: a prospective study. Arthritis and rheumatism, 2006, Oct-15, Volume: 55, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Arthritis, Gouty; Benzbromarone; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Gout Suppressants; Humans; Life Style; Middle Aged; Predictive Value of Tests; Prospective Studies; Secondary Prevention; Time Factors; Uric Acid	2006
Excellent response to the clinical treatment of tophaceous gout. Clinical rheumatology, 2007, Volume: 26, Issue:9 Topics: Aged; Allopurinol; Benzbromarone; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Kidney Failure, Chronic; Male; Treatment Outcome; Uric Acid; Uricosuric Agents	2007
Time required for disappearance of urate crystals from synovial fluid after successful hypouricaemic treatment relates to the duration of gout. Annals of the rheumatic diseases, 2007, Volume: 66, Issue:8 Topics: Adult; Aged; Benzbromarone; Chronic Disease; Crystallization; Follow-Up Studies; Gout; Gout Suppressants; Humans; Knee Joint; Male; Metatarsophalangeal Joint; Middle Aged; Statistics, Nonparametric; Synovial Fluid; Time Factors; Treatment Outcome; Uric Acid	2007
Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:6 Topics: Benzbromarone; Cell Line; Flavonoids; Humans; Kidney; Organic Anion Transporters; Organic Cation Transport Proteins; Probenecid; Sulfinpyrazone; Transfection; Uric Acid; Uricosuric Agents	2007
Mouse GLUT9: evidences for a urate uniporter. American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:3 Topics: Animals; Benzbromarone; Biological Transport; Chlorides; Glucose; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 2; Kinetics; Losartan; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Nephrons; Oocytes; Organic Anion Transporters; Phloretin; Protein Isoforms; RNA, Messenger; Sodium; Species Specificity; Uric Acid; Uricosuric Agents; Xenopus laevis	2009
Effect of losartan and benzbromarone on the level of human urate transporter 1 mRNA. Arzneimittel-Forschung, 2010, Volume: 60, Issue:4 Topics: Angiotensin II Type 1 Receptor Blockers; Benzbromarone; Cell Line; Humans; Kidney; Losartan; Organic Anion Transporters; Organic Cation Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uric Acid; Uricosuric Agents	2010
Risk factors associated with renal lithiasis during uricosuric treatment of hyperuricemia in patients with gout. Arthritis care & research, 2010, Volume: 62, Issue:9 Topics: Allopurinol; Benzbromarone; Cohort Studies; Creatinine; Follow-Up Studies; Gout; Humans; Hyperuricemia; Middle Aged; Proportional Hazards Models; Prospective Studies; Renal Colic; Risk Factors; Time Factors; Uric Acid; Uricosuric Agents; Urolithiasis	2010
Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats. Biochimica et biophysica acta, 2011, Volume: 1808, Issue:6 Topics: Animals; Anion Transport Proteins; Benzbromarone; Biological Transport; Epithelial Cells; Female; Humans; Immunohistochemistry; Kidney; Kinetics; Lactates; Male; Microvilli; Oocytes; Pyrazinamide; Rats; Rats, Sprague-Dawley; Rats, Wistar; Uric Acid; Xenopus laevis	2011
Hyperuricemia attenuates aortic nitric oxide generation, through inhibition of arginine transport, in rats. Journal of vascular research, 2011, Volume: 48, Issue:3 Topics: Allopurinol; Animals; Aorta; Arginine; Benzbromarone; Biological Transport; Blood Pressure; Cationic Amino Acid Transporter 1; Disease Models, Animal; Hyperuricemia; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxonic Acid; Phosphorylation; Protein Kinase C-alpha; Rats; Rats, Wistar; Tyrosine; Uric Acid; Uricosuric Agents	2011
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs. Nephrology (Carlton, Vic.), 2011, Volume: 16, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Benzothiazoles; Biological Transport; Captopril; Cells, Cultured; Dogs; Enalapril; Indomethacin; Inhibitory Concentration 50; Organic Anion Transporters; Organic Cation Transport Proteins; Phenylbutazone; Probenecid; Pyridines; Salicylates; Sulfinpyrazone; Uric Acid; Uricosuric Agents	2011
Human urate transporter 1 (hURAT1) mediates the transport of orotate. The journal of physiological sciences : JPS, 2011, Volume: 61, Issue:3 Topics: Animals; Benzbromarone; Biological Transport; Carrier Proteins; Cells, Cultured; HEK293 Cells; Humans; Kidney; Oocytes; Organic Anion Transporters; Organic Cation Transport Proteins; Orotic Acid; Uric Acid; Uricosuric Agents; Xenopus	2011
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. Nephron. Experimental nephrology, 2012, Volume: 120, Issue:1 Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis; Hyperuricemia; Immunohistochemistry; Kidney; Kidney Diseases; Male; Osteopontin; Random Allocation; Rats; Rats, Sprague-Dawley; Uric Acid; Uricosuric Agents; Vascular Endothelial Growth Factor A; Xanthine Oxidase	2012
Efficacy of benzbromarone in hyperuricemic patients associated with chronic kidney disease. Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:12 Topics: Benzbromarone; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Kidney Failure, Chronic; Male; Middle Aged; Treatment Outcome; Uric Acid; Uricosuric Agents	2011
Relationship between serum allantoin and urate in healthy subjects and effects of benzbromarone in gout patients. International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Allantoin; Benzbromarone; Biomarkers; Case-Control Studies; Creatinine; Deoxyguanosine; Dinoprost; Gout; Humans; Hyperuricemia; Japan; Male; Middle Aged; Oxidative Stress; Time Factors; Treatment Outcome; Uric Acid; Uricosuric Agents	2012
Anti-inflammatory and immunomodulatory effects of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats. Life sciences, 2012, Oct-05, Volume: 91, Issue:11-12 Topics: Actins; Allopurinol; Animals; Anti-Inflammatory Agents; Benzbromarone; Chemokine CCL2; Cyclopentane Monoterpenes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Immunologic Factors; Iridoid Glycosides; Kidney; Kidney Diseases; Male; Medicine, Chinese Traditional; Pyrans; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rubiaceae; Transcription Factor RelA; Uric Acid	2012
Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:3 Topics: Animals; Benzbromarone; Cells, Cultured; Dogs; Fluorescent Antibody Technique; Glucose Transport Proteins, Facilitative; Humans; Kidney; Lactic Acid; Madin Darby Canine Kidney Cells; Niacin; Oocytes; Organic Anion Transporters; Organic Cation Transport Proteins; Pyrazinamide; Uric Acid; Uricosuric Agents; Vasodilator Agents; Xenopus laevis	2013
New approach to assess bioequivalence parameters using generalized gamma mixed-effect model (model-based asymptotic bioequivalence test). Statistics in medicine, 2014, Feb-28, Volume: 33, Issue:5 Topics: Algorithms; Benzbromarone; Ciprofloxacin; Computer Simulation; Cross-Over Studies; Humans; Male; Models, Statistical; Monte Carlo Method; Multivariate Analysis; Therapeutic Equivalency; Uric Acid	2014
[Effect of total saponin of Dioscorea on chronic hyperuricemia and expression of URAT1 in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:14 Topics: Animals; Anion Transport Proteins; Benzbromarone; Dioscorea; Gout Suppressants; Hyperuricemia; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Saponins; Uric Acid; Xanthine Oxidase	2013
Prevention of comorbidity and acute attack of gout by uric acid lowering therapy. Journal of Korean medical science, 2014, Volume: 29, Issue:5 Topics: Adult; Allopurinol; Antimetabolites; Benzbromarone; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Retrospective Studies; Thiazoles; Uric Acid; Uricosuric Agents; Urolithiasis	2014
Influence of urate-lowering therapies on renal handling of uric acid. Clinical rheumatology, 2016, Volume: 35, Issue:1 Topics: Adult; Antihypertensive Agents; Benzbromarone; Case-Control Studies; Creatinine; Glomerular Filtration Rate; Gout; Humans; Hypertension; Kidney; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2016
Is hyperuricemia a risk factor for arteriosclerosis? Uric acid and arteriosclerosis in apolipoprotein e-deficient mice. Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:12 Topics: Aging; Allopurinol; Animal Feed; Animals; Apolipoproteins E; Arteriosclerosis; Benzbromarone; Diet; Gene Expression Regulation; Gout Suppressants; Hyperuricemia; Male; Mice; Mice, Knockout; Risk Factors; Uric Acid; Uricosuric Agents	2014
Activation of peripheral KCNQ channels relieves gout pain. Pain, 2015, Volume: 156, Issue:6 Topics: Action Potentials; Animals; Animals, Newborn; Arthritis; Benzbromarone; Cells, Cultured; CHO Cells; Cricetulus; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Hippocampus; Inflammation; KCNQ2 Potassium Channel; Male; Mice; Mice, Inbred Strains; Neurons; Rats; Rats, Sprague-Dawley; Uric Acid; Uricosuric Agents	2015
Direct radical scavenging activity of benzbromarone provides beneficial antioxidant properties for hyperuricemia treatment. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:3 Topics: Antioxidants; Benzbromarone; Cell Line; Endothelial Cells; Free Radical Scavengers; Human Umbilical Vein Endothelial Cells; Humans; Hyperuricemia; Kidney; Oxidative Stress; Reactive Oxygen Species; Superoxides; Uric Acid	2015
Salivary uric acid as a noninvasive biomarker for monitoring the efficacy of urate-lowering therapy in a patient with chronic gouty arthropathy. Clinica chimica acta; international journal of clinical chemistry, 2015, Oct-23, Volume: 450 Topics: Arthritis, Gouty; Benzbromarone; Biomarkers; Chronic Disease; Feasibility Studies; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Saliva; Treatment Outcome; Uric Acid	2015
Outcome of Treatment in Gouty Arthritis Patients: A Retrospective Study. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015, Volume: 98 Suppl 3 Topics: Alcohol Drinking; Allopurinol; Arthritis, Gouty; Benzbromarone; Female; Follow-Up Studies; Gout Suppressants; Humans; Kidney Function Tests; Male; Middle Aged; Retrospective Studies; Risk Factors; Treatment Outcome; Uric Acid; Uricosuric Agents	2015
Chinese Herbal Formulas Si-Wu-Tang and Er-Miao-San Synergistically Ameliorated Hyperuricemia and Renal Impairment in Rats Induced by Adenine and Potassium Oxonate. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 37, Issue:4 Topics: Adenine; Administration, Oral; Animals; Benzbromarone; Creatinine; Drug Synergism; Drugs, Chinese Herbal; Hyperuricemia; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Plant Exudates; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase	2015
Stronger Uricosuric Effects of the Novel Selective URAT1 Inhibitor UR-1102 Lowered Plasma Urate in Tufted Capuchin Monkeys to a Greater Extent than Benzbromarone. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:1 Topics: Animals; Benzbromarone; Cebus; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; HEK293 Cells; Humans; Male; Microsomes, Liver; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Oxazines; Protein Binding; Pyridines; Uric Acid; Uricosuric Agents	2016
Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents. Drug research, 2016, Volume: 66, Issue:5 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzbromarone; Biphenyl Compounds; Cells, Cultured; Glucose Transport Proteins, Facilitative; Human Umbilical Vein Endothelial Cells; Humans; Irbesartan; Losartan; Monocarboxylic Acid Transporters; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Tetrazoles; Uric Acid; Uricosuric Agents	2016
Allopurinol decreases serum uric acid level and intestinal glucose transporter-5 expression in rats with fructose-induced hyperuricemia. Pharmacological reports : PR, 2016, Volume: 68, Issue:4 Topics: Allopurinol; Animals; Benzbromarone; Fructose; Glucose Transporter Type 2; Glucose Transporter Type 5; Hyperuricemia; Intestinal Mucosa; Liver; Male; Rats; Uric Acid; Xanthine Oxidase	2016
The safety and efficacy of benzbromarone in gout in Aotearoa New Zealand. Internal medicine journal, 2016, Volume: 46, Issue:9 Topics: Aged; Allopurinol; Benzbromarone; Comorbidity; Exanthema; Female; Gout; Gout Suppressants; Humans; Kidney Function Tests; Liver Function Tests; Male; Middle Aged; New Zealand; Retrospective Studies; Uric Acid; Uricosuric Agents	2016
A study comparing the safety and efficacy of febuxostat, allopurinol, and benzbromarone in Chinese gout patients: a retrospective cohort study . International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:2 Topics: Adult; Allopurinol; Asian People; Benzbromarone; Biomarkers; China; Drug Dosage Calculations; Febuxostat; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Remission Induction; Retrospective Studies; Time Factors; Treatment Outcome; Uric Acid	2017
Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Scientific reports, 2017, 04-06, Volume: 7, Issue:1 Topics: Adult; Animals; Benzbromarone; Biological Transport; Dose-Response Relationship, Drug; Gout; HEK293 Cells; Humans; Hyperuricemia; Inhibitory Concentration 50; Kinetics; Male; Molecular Targeted Therapy; Mutation; Organic Anion Transporters; Organic Cation Transport Proteins; Protein Binding; Rats; Uric Acid; Uricosuric Agents; Young Adult	2017
Prescription pattern of urate-lowering therapy in Korean gout patients: data from the national health claims database. The Korean journal of internal medicine, 2018, Volume: 33, Issue:1 Topics: Allopurinol; Benzbromarone; Databases, Factual; Febuxostat; Gout; Gout Suppressants; Humans; Republic of Korea; Uric Acid	2018
[Effect of Chinese herb chicory extract on expression of renal transporter Glut9 in rats with hyperuricemia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:5 Topics: Animals; Benzbromarone; Cichorium intybus; Drugs, Chinese Herbal; Hyperuricemia; Kidney; Male; Monosaccharide Transport Proteins; Plant Extracts; Rats; Rats, Sprague-Dawley; Uric Acid	2017
Comparative effectiveness of allopurinol, febuxostat and benzbromarone on renal function in chronic kidney disease patients with hyperuricemia: a 13-year inception cohort study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018, 09-01, Volume: 33, Issue:9 Topics: Aged; Allopurinol; Benzbromarone; Cohort Studies; Disease Progression; Drug Monitoring; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Incidence; Male; Middle Aged; Renal Insufficiency, Chronic; Taiwan; Uric Acid; Uricosuric Agents	2018
Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor. Molecules (Basel, Switzerland), 2018, Jan-27, Volume: 23, Issue:2 Topics: Benzbromarone; Biological Transport, Active; Carbon Radioisotopes; Drug Design; Gene Expression; HEK293 Cells; Humans; Methane; Organic Anion Transporters; Organic Cation Transport Proteins; Structure-Activity Relationship; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents	2018
Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation. Bioorganic & medicinal chemistry letters, 2018, 12-15, Volume: 28, Issue:23-24 Topics: Activation, Metabolic; Animals; Benzbromarone; Chemistry Techniques, Synthetic; HEK293 Cells; Hepatocytes; Humans; Mice; Microsomes, Liver; Mitochondria; Organic Anion Transporters; Organic Cation Transport Proteins; Rats; Uric Acid; Uricosuric Agents	2018
Associations between urate-lowering therapy and the risk of type 2 diabetes mellitus. PloS one, 2019, Volume: 14, Issue:1 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Allopurinol; Benzbromarone; Case-Control Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Prevalence; Proportional Hazards Models; Taiwan; Treatment Outcome; Uric Acid; Young Adult	2019
Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy. Diabetes, 2019, Volume: 68, Issue:5 Topics: Allopurinol; Animals; Benzbromarone; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; Hyperuricemia; Inflammation; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Retina; Risk Factors; Uric Acid; Vitreous Body; Xanthine Oxidase	2019
Efficacy of uric acid-lowering therapy on hypercholesterolemia and hypertriglyceridemia in gouty patients. International journal of rheumatic diseases, 2019, Volume: 22, Issue:8 Topics: Adult; Allopurinol; Benzbromarone; Biomarkers; Cholesterol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hypercholesterolemia; Hypertriglyceridemia; Male; Middle Aged; Retrospective Studies; Time Factors; Treatment Outcome; Triglycerides; Uric Acid; Uricosuric Agents	2019
Effects of Conventional Uric Acid-Lowering Therapy on Monosodium Urate Crystal Deposits. Arthritis & rheumatology (Hoboken, N.J.), 2020, Volume: 72, Issue:1 Topics: Aged; Alcohol Drinking; Allopurinol; Benzbromarone; Diet Therapy; Febuxostat; Female; Foot Joints; Fructose; Gout; Gout Suppressants; Humans; Male; Meat; Middle Aged; Prospective Studies; Purines; Shellfish; Tomography, X-Ray Computed; Uric Acid; Uricosuric Agents	2020
Impact of urate-lowering drugs on the progression and recovery from chronic kidney disease among gout patients. Arthritis research & therapy, 2019, 09-18, Volume: 21, Issue:1 Topics: Allopurinol; Benzbromarone; Disease Progression; Febuxostat; Female; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Incidence; Male; Middle Aged; Recovery of Function; Renal Insufficiency, Chronic; Treatment Outcome; Uric Acid; Uricosuric Agents	2019
Clinical efficacy and safety of benzbromarone in elderly hypertensive patients with hyperuricemia. Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:4(Suppleme Topics: Aged; Benzbromarone; Blood Pressure; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Hyperuricemia; Incidence; Male; Treatment Outcome; Uric Acid; Uricosuric Agents	2019
Urate Transporter URAT1 in Hyperuricemia: New Insights from Hyperuricemic Models. Annals of clinical and laboratory science, 2019, Volume: 49, Issue:6 Topics: Animals; Benzbromarone; Disease Models, Animal; Febuxostat; HEK293 Cells; Humans; Hyperuricemia; Kidney; Male; Mice, Inbred ICR; Organic Anion Transporters; Organic Cation Transport Proteins; Uric Acid	2019
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:3 Topics: Adult; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Benzbromarone; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-18; Interleukin-1beta; Leukocytes, Mononuclear; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Nuclear Factor 45 Protein; Plaque, Atherosclerotic; Reactive Oxygen Species; Receptors, LDL; Urate Oxidase; Uric Acid; Uricosuric Agents; Xanthine Oxidase; Young Adult	2020
Characterizations of the Urate Transporter, GLUT9, and Its Potent Inhibitors by Patch-Clamp Technique. SLAS discovery : advancing life sciences R & D, 2021, Volume: 26, Issue:3 Topics: Animals; Benzbromarone; Biological Transport; Gene Expression; Glucose Transport Proteins, Facilitative; Gout Suppressants; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Mice; Naphthalenes; Patch-Clamp Techniques; Plasmids; Potassium; Probenecid; Propionates; Pyridines; Transgenes; Uric Acid	2021
Repair of Bone Erosion With Effective Urate-Lowering Therapy in a Patient With Tophaceous Gout. Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:2 Topics: Benzbromarone; Bone Resorption; Enzyme Inhibitors; Gout; Humans; Male; Metatarsal Bones; Metatarsophalangeal Joint; Middle Aged; Nitriles; Osteogenesis; Osteophyte; Pyridines; Treatment Outcome; Uric Acid; Uricosuric Agents; Xanthine Oxidase	2021
Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications. Cardiovascular toxicology, 2021, Volume: 21, Issue:3 Topics: Actins; Animals; Apoptosis; Atrial Fibrillation; Atrial Remodeling; bcl-2-Associated X Protein; Benzbromarone; Biomarkers; Caspase 3; Cells, Cultured; Disease Models, Animal; Fibrosis; Heart Atria; Hyperuricemia; Male; Myocytes, Cardiac; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Uric Acid; Uricosuric Agents	2021
Novel monocyclic amide-linked phenol derivatives without mitochondrial toxicity have potent uric acid-lowering activity. Bioorganic & medicinal chemistry letters, 2021, 05-15, Volume: 40 Topics: Amides; Animals; Benzbromarone; Drug Evaluation, Preclinical; Glucose Transport Proteins, Facilitative; Humans; Mitochondria; Phenol; Pyrroles; Sapajus apella; Signal Transduction; Structure-Activity Relationship; Uric Acid; Uricosuric Agents	2021
Drastic monosodium urate crystal dissolution with febuxostat and benzbromarone. Joint bone spine, 2021, Volume: 88, Issue:4 Topics: Allopurinol; Benzbromarone; Febuxostat; Gout; Gout Suppressants; Humans; Solubility; Uric Acid	2021
Synthesis and bioactivity evaluation of novel nuciferine derivatives with antihyperuricemia and nephroprotective effects. Bioorganic chemistry, 2022, Volume: 126 Topics: Animals; Aporphines; Benzbromarone; Hyperuricemia; Mice; Molecular Docking Simulation; Organic Anion Transporters; Phosphatidylinositol 3-Kinases; Uric Acid	2022
Hypouricemic effect of 2,4-dihydroxybenzoic acid methyl ester in hyperuricemic mice through inhibiting XOD and down-regulating URAT1. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153 Topics: Allopurinol; Animals; Benzbromarone; Esters; Hydroxybenzoates; Hyperuricemia; Kidney; Mice; Uric Acid; Xanthine Oxidase	2022
Discovery of novel benzbromarone analogs with improved pharmacokinetics and benign toxicity profiles as antihyperuricemic agents. European journal of medicinal chemistry, 2022, Nov-15, Volume: 242 Topics: Animals; Benzbromarone; Hyperuricemia; Mice; Organic Anion Transporters; Organic Cation Transport Proteins; Uric Acid; Uricosuric Agents	2022
Short-Term Hyperuricemia Leads to Structural Retinal Changes That Can be Reversed by Serum Uric Acid Lowering Agents in Mice. Investigative ophthalmology & visual science, 2022, 09-01, Volume: 63, Issue:10 Topics: Allopurinol; Angiotensin II; Animals; Benzbromarone; Hyperuricemia; Macular Degeneration; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred ICR; Uric Acid	2022
Cardiovascular risk of urate-lowering drugs: A study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan. Clinical and translational science, 2023, Volume: 16, Issue:2 Topics: Allopurinol; Benzbromarone; Cardiovascular Diseases; Febuxostat; Gout; Gout Suppressants; Heart Disease Risk Factors; Humans; Insurance, Health; Japan; Risk Factors; Treatment Outcome; Uric Acid	2023
Uricosuric Agents Affect Plasma and Kidney Concentration of Adefovir via Inhibition of Oat1 and Mrp2 in Rats. Biological & pharmaceutical bulletin, 2023, Volume: 46, Issue:2 Topics: Animals; Benzbromarone; Kidney; Organic Anion Transporters; Probenecid; Rats; Rats, Sprague-Dawley; Uric Acid; Uricosuric Agents	2023
The risk of ischemic cerebrovascular disease associated with benzbromarone use in gout people: A retrospective cohort study in Taiwan. Medicine, 2023, Feb-03, Volume: 102, Issue:5 Topics: Benzbromarone; Cerebrovascular Disorders; Gout; Gout Suppressants; Humans; Retrospective Studies; Taiwan; Uric Acid; Uricosuric Agents	2023
Superiority of low-dose benzbromarone to low-dose febuxostat in gout patients with renal uric acid underexcretion: comment on the article by Yan et al. Arthritis & rheumatology (Hoboken, N.J.), 2023, Volume: 75, Issue:9 Topics: Allopurinol; Benzbromarone; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Treatment Outcome; Uric Acid	2023
Comparison of benzbromarone and allopurinol on the risk of chronic kidney disease in people with asymptomatic hyperuricemia. European journal of internal medicine, 2023, Volume: 113 Topics: Allopurinol; Benzbromarone; Female; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Renal Insufficiency, Chronic; Retrospective Studies; Uric Acid	2023