uric acid and acetylcysteine

uric acid has been researched along with acetylcysteine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.12)18.7374
1990's6 (18.18)18.2507
2000's8 (24.24)29.6817
2010's12 (36.36)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Bravo-Díaz, C; Losada-Barreiro, S1
Salemnick, G; Stöhrer, G1
Birkett, DJ; Lelo, A; Miners, JO1
Burns, JR; Finlayson, B; Gauthier, JF1
Ackermann, D; Alken, P; Frohneberg, D; Weirich, W1
Kondo, H; Niki, E; Takahashi, M1
Hughes, CM; Lewis, SE; McKelvey-Martin, VJ; Thompson, W1
Altindag, ZZ; Fuchs, D; Wachter, H; Wede, I; Widner, B1
Clark, JE; Foresti, R; Green, CJ; Motterlini, R; Sarathchandra, P1
Costa-Bauzá, A; Grases, F; Ramis, M; Villacampa, AI1
Delogu, MR; Desole, MS; Enrico, P; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA1
Cheng, KY; Geller, HM; Goldsmith, NK; Grandison, L; Morris, EJ; Romero, AA; Zhang, AL1
Delogu, MR; Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Rocchitta, G; Serra, PA1
ROBINSON, D; SMITH, JN; WILLIAMS, RT1
Hsu, CC; Lin, CC; Lin, MP; Yin, MC1
John, SA; Kalimuthu, P; Suresh, D1
Ginsburg, I; Kohen, R; Koren, E; Zverev, I1
Kimura, H; Naka, A; Suzuki, T1
Ostapiuk, J; Szyszka, K; Zembron-Lacny, A1
Pfleiderer, W; Suzuki, T; Yamamoto, H1
Aurrekoetxea, I; del Agua, AR; Elorriaga, MA; Guéraud, F; Rodriguez, F; Ruiz-Larrea, MB; Ruiz-Sanz, JI1
Sharma, S; Shrivastava, S; Shukla, S1
Cheng, J; Hisatome, I; Hu, Y; Huang, T; Li, Z; Luo, C; Luo, Y; Yamamoto, T; Yuan, H; Zhang, Y; Zhu, Y1
Atella, GC; Coelho, MG; Cunha, PR; Justo, GA; Laranja, GA; Nogueira, NP; Paes, MC; Rossini, A; Sabino, KC; Saraiva, FM; Sultano, PE1
Lee, CT; Wang, JY; Yu, LE1
Cai, B; Cheng, J; Hisatome, I; Hong, L; Hu, Y; Huang, J; Huang, T; Li, Z; Lian, X; Luo, C; Wen, T; Yamamoto, T; Yuan, H; Zhang, X; Zhang, Y; Zhu, Y; Zhuang, W; Zou, J1
Cheng, J; Hisatome, I; Hong, L; Hu, Y; Li, Z; Luo, C; Wen, T; Yamamoto, T; Yuan, H; Zhang, X; Zhang, Y; Zhu, Y; Zhuang, W; Zou, J1
Chen, Y; Cheng, J; Li, Z; Shen, Y; Wang, W; Zhang, G1
Alberts, BM; Basnayake, K; Bruce, C; Davies, KA; Ghezzi, P; Mullen, LM1
Heidarian, E; Nouri, A1
Aceti, A; Austin, T; Corvaglia, L; Faldella, G; Martini, S1
Cabezas, R; Elsaid, KA; ElSayed, S; Jay, GD; Qadri, M; Schmidt, TA1
Berga, F; Costa-Bauza, A; Grases, F; Julià, F1

Reviews

2 review(s) available for uric acid and acetylcysteine

ArticleYear
Free radicals and polyphenols: The redox chemistry of neurodegenerative diseases.
    European journal of medicinal chemistry, 2017, Jun-16, Volume: 133

    Topics: Animals; Free Radicals; Humans; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Polyphenols; Reactive Oxygen Species

2017
Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives.
    Pediatric research, 2020, Volume: 87, Issue:5

    Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Asphyxia Neonatorum; Biomarkers; Brain Injuries; Clinical Trials as Topic; DNA; Erythropoietin; Free Radicals; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Prostaglandins; Proteins; Uric Acid

2020

Trials

1 trial(s) available for uric acid and acetylcysteine

ArticleYear
Effects of sulphur-containing compounds on plasma redox status in muscle-damaging exercise.
    The Chinese journal of physiology, 2009, Oct-31, Volume: 52, Issue:5

    Topics: Acetylcysteine; Antioxidants; Dose-Response Relationship, Drug; Exercise; Humans; Male; Oxidation-Reduction; Protein Carbonylation; Resistance Training; Sulfhydryl Compounds; Taurine; Thiobarbituric Acid Reactive Substances; Thioctic Acid; Uric Acid; Young Adult

2009

Other Studies

30 other study(ies) available for uric acid and acetylcysteine

ArticleYear
Oxidizing action of purine N-oxide esters.
    Cancer research, 1975, Volume: 35, Issue:1

    Topics: Acetylation; Acetylcysteine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclic N-Oxides; Cysteine; Esters; Guanine; Hydrogen-Ion Concentration; Iodides; Iodine; Mercaptopurine; Methionine; Oxidation-Reduction; Purines; Pyridines; Sulfates; Sulfhydryl Compounds; Tryptophan; Tyrosine; Uric Acid; Xanthines

1975
Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:8

    Topics: Acetylcysteine; Animals; Cimetidine; Cysteine; Cytochrome P-450 Enzyme System; Dithiothreitol; Glutathione; Kinetics; Male; Metyrapone; Microsomes, Liver; Pyridines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theobromine; Uracil; Uric Acid

1990
Dissolution kinetics of uric acid calculi.
    The Journal of urology, 1984, Volume: 131, Issue:4

    Topics: Acetylcysteine; Bicarbonates; Electrolytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Sodium Bicarbonate; Sodium Chloride; Solubility; Tromethamine; Uric Acid; Urinary Calculi

1984
[Practical experiences with antegrade local chemolysis of struvite/apatite, uric acid and cystine calculi in the kidney].
    Der Urologe. Ausg. A, 1984, Volume: 23, Issue:2

    Topics: Acetylcysteine; Apatites; Bicarbonates; Citrates; Combined Modality Therapy; Cystine; Female; Humans; Kidney Calculi; Magnesium; Magnesium Compounds; Male; Middle Aged; Phosphates; Recurrence; Sodium Bicarbonate; Struvite; Therapeutic Irrigation; Uric Acid

1984
Peroxynitrite-induced hemolysis of human erythrocytes and its inhibition by antioxidants.
    FEBS letters, 1997, Aug-18, Volume: 413, Issue:2

    Topics: Acetylcysteine; Albumins; Amidines; Antioxidants; Azoles; Catalase; Chromans; Erythrocytes; Glutathione; Hematocrit; Hemolysis; Humans; Isoindoles; Molsidomine; Nitrates; Organoselenium Compounds; Uric Acid; Vitamin E

1997
The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity.
    Human reproduction (Oxford, England), 1998, Volume: 13, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Separation; DNA; DNA Damage; Humans; In Vitro Techniques; Infertility, Male; Male; Povidone; Reactive Oxygen Species; Reproductive Techniques; Silicon Dioxide; Spermatozoa; Uric Acid; Vitamin E

1998
Inhibition of xanthine oxidase by pterins.
    Free radical research, 1998, Volume: 29, Issue:4

    Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Edetic Acid; Ferric Compounds; Formazans; Hydrogen-Ion Concentration; Nitroblue Tetrazolium; Oxidation-Reduction; Pterins; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Superoxides; Time Factors; Uric Acid; Xanthine; Xanthine Oxidase

1998
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis.
    The Biochemical journal, 1999, May-01, Volume: 339 ( Pt 3)

    Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Apoptosis; Bilirubin; Cattle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; Free Radical Scavengers; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Metalloporphyrins; Nitrates; Protoporphyrins; Thiourea; Time Factors; Uric Acid

1999
Uric acid urolithiasis and crystallization inhibitors.
    Urologia internationalis, 1999, Volume: 62, Issue:4

    Topics: Acetylcysteine; Citric Acid; Crystallization; Glycosaminoglycans; Humans; Mucins; Phytic Acid; Saponins; Sodium Dodecyl Sulfate; Surface-Active Agents; Uric Acid; Urinary Calculi

1999
Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis Solutions; Dopamine; Homovanillic Acid; Infusion Pumps; Levodopa; Male; Manganese; Manganese Compounds; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Wistar; Time Factors; Uric Acid

2000
Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside.
    Journal of neurochemistry, 2001, Volume: 78, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Biological Transport; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytarabine; Dipyridamole; DNA Damage; Embryo, Mammalian; Free Radical Scavengers; Kinetics; Models, Neurological; Neurons; Oxidative Stress; Rats; Uric Acid; Vitamin E

2001
A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Corpus Striatum; Deferoxamine; Dialysis Solutions; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Iron; Male; Metalloporphyrins; Molsidomine; Movement; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Uric Acid

2001
Studies in detoxication. 52. The apparent dissociation constants of some glucuronides, mercapturic acids and related compounds.
    The Biochemical journal, 1953, Volume: 55, Issue:1

    Topics: Acetylcysteine; Glucuronates; Glucuronides; Hippurates; Uric Acid

1953
Effect of five cysteine-containing compounds on three lipogenic enzymes in Balb/cA mice consuming a high saturated fat diet.
    Lipids, 2004, Volume: 39, Issue:9

    Topics: Acetylcysteine; Animals; Blood Glucose; Cysteine; Diet; Dietary Fats; Fatty Acid Synthases; Fatty Acids; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Hyperlipidemias; Insulin; Kidney; Liver; Malate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Myocardium; Uric Acid

2004
Uric acid determination in the presence of ascorbic acid using self-assembled submonolayer of dimercaptothiadiazole-modified gold electrodes.
    Analytical biochemistry, 2006, Oct-15, Volume: 357, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Electrochemistry; Electrodes; Gold; Models, Molecular; Thiadiazoles; Uric Acid

2006
Supplementation with antioxidants fails to increase the total antioxidant capacity of several cell lines in culture.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2008, Volume: 62, Issue:3

    Topics: Acetylcysteine; Antimetabolites; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Chromatography, High Pressure Liquid; Electrochemistry; Ferric Compounds; Free Radical Scavengers; Glutathione; Humans; Keratinocytes; Proteins; Reactive Oxygen Species; Uric Acid

2008
Effects of uric acid on nitrosation of N-acetylcysteine by diethylamine NONOate and N-acetyl-N-nitrosotryptophan.
    Chemical & pharmaceutical bulletin, 2009, Volume: 57, Issue:7

    Topics: Acetylcysteine; Azo Compounds; Diethylamines; Nitrosamines; Nitrosation; Tryptophan; Uric Acid

2009
Nitrosation of N-methyl derivatives of uric acid and their transnitrosation ability to N-acetylcysteine.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:9

    Topics: Acetylcysteine; Nitric Oxide; Nitrosation; Uric Acid

2010
Involvement of G-463A MPO gene polymorphism in the response of postmenopausal women to hormone therapy.
    Menopause (New York, N.Y.), 2011, Volume: 18, Issue:5

    Topics: Acetylcysteine; alpha-Tocopherol; Antioxidants; Estradiol; Female; Hormone Replacement Therapy; Humans; Intercellular Adhesion Molecule-1; Lipids; Malondialdehyde; Middle Aged; Peroxidase; Polymorphism, Genetic; Postmenopause; Progesterone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Uric Acid

2011
Reversal of lead-induced toxicity due to the effect of antioxidants.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2013, Volume: 32, Issue:2

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Brain; Cholesterol; Glutathione; Injections, Intraperitoneal; Kidney; Lead; Lead Poisoning; Liver; Male; Organometallic Compounds; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Uric Acid

2013
High uric acid directly inhibits insulin signalling and induces insulin resistance.
    Biochemical and biophysical research communications, 2014, May-16, Volume: 447, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glucose Intolerance; Hep G2 Cells; Humans; Hyperuricemia; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Uric Acid

2014
Proliferation and differentiation of Trypanosoma cruzi inside its vector have a new trigger: redox status.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Cycle; Cell Proliferation; Heme; Hydrogen Peroxide; Insect Vectors; Oxidation-Reduction; Rhodnius; Trypanosoma cruzi; Uric Acid

2015
Nitroxide antioxidant as a potential strategy to attenuate the oxidative/nitrosative stress induced by hydrogen peroxide plus nitric oxide in cultured neurons.
    Nitric oxide : biology and chemistry, 2016, Apr-01, Volume: 54

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cyclic N-Oxides; Hydrogen Peroxide; L-Lactate Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Thiourea; Uric Acid

2016
High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:3-4

    Topics: Acetylcysteine; AMP-Activated Protein Kinases; Antigens, CD; Antigens, Differentiation, Myelomonocytic; ATP Binding Cassette Transporter, Subfamily G, Member 1; Cell Differentiation; Cell Line; Cyclooxygenase 2; Foam Cells; Humans; Lipoproteins, LDL; Models, Biological; Monocytes; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA; Uric Acid

2016
Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells.
    Molecular and cellular endocrinology, 2017, 03-05, Volume: 443

    Topics: 4-Chloro-7-nitrobenzofurazan; Acetylcysteine; Adenylate Kinase; Animals; Antioxidants; Cell Line; Deoxyglucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Mice; Models, Biological; Muscle Cells; Muscle, Skeletal; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Uric Acid

2017
High Uric Acid Inhibits Cardiomyocyte Viability Through the ERK/P38 Pathway via Oxidative Stress.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:3

    Topics: Acetylcysteine; Animals; Cell Line; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hyperuricemia; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Uric Acid

2018
Secretion of IL-1β From Monocytes in Gout Is Redox Independent.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Acetylcysteine; Antioxidants; Cell Survival; Furans; Gene Expression; Gout; Heterocyclic Compounds, 4 or More Rings; Humans; Hyperuricemia; Indenes; Inflammasomes; Interleukin-1beta; Lipopeptides; Monocytes; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Renal Insufficiency, Chronic; Sulfonamides; Sulfones; Superoxide Dismutase; Thioredoxin Reductase 1; Toll-Like Receptor 2; Uric Acid

2019
Ameliorative effects of N-acetyl cysteine on diclofenac-induced renal injury in male rats based on serum biochemical parameters, oxidative biomarkers, and histopathological study.
    Journal of food biochemistry, 2019, Volume: 43, Issue:8

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Biomarkers; Creatinine; Diclofenac; Humans; Kidney; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Uric Acid

2019
Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents; Female; Free Radical Scavengers; Gout; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Leukocytes, Mononuclear; Male; Mice; Mice, Knockout; Middle Aged; Neutrophils; Phagocytosis; Protein Phosphatase 2; Proteoglycans; Reactive Oxygen Species; Recombinant Proteins; THP-1 Cells; Uric Acid

2021
Effect of theobromine on dissolution of uric acid kidney stones.
    World journal of urology, 2022, Volume: 40, Issue:8

    Topics: Acetylcysteine; Humans; Kidney Calculi; Solubility; Theobromine; Uric Acid

2022