Compounds > urea

urea and zj43

urea has been researched along with zj43 in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's9 (56.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barton, FB; Bukhari, N; Bzdega, T; Kozikowski, AP; Neale, JH; Olszewski, RT; Shamimi-Noori, S; Vicini, S; Wroblewska, B; Wroblewski, JT; Zhou, J1
Grajkowska, E; Hirasawa, S; Kozikowski, A; Neale, JH; Wroblewska, B; Wroblewski, J; Yamamoto, T; Zhou, J1
Kozikowski, A; Lyeth, BG; Neale, JH; Sarva, J; Zhao, X; Zhong, C1
Aoe, T; Kozikowski, A; Neale, JH; Saito, O; Sarva, J; Yamamoto, T1
Aoe, T; Bartolozzi, A; Bzdega, T; Kozikowski, A; Neale, JH; Saito, O; Sarva, J; Wroblewska, B; Yamamoto, T; Zhou, J1
Deutsch, SI; Kozikowski, AP; Krolikowski, KA; Long, K; Mastropaolo, J; Monteiro, AC; Neale, JH; Olszewski, RT; Wegorzewska, MM; Zhou, J1
Kozikowski, A; Neale, JH; Yamamoto, T; Zhou, J1
Adedoyin, MO; Neale, JH; Vicini, S1
Krolikowski, KA; Neale, JH; Olszewski, RT; Profaci, CP1
Feng, JF; Gurkoff, GG; Kopriva, C; Lowe, DA; Lyeth, BG; Neale, JH; Olszewski, RT; Song, M; Sun, S; Van, KC; Xu, M; Yuen, PW; Zhou, J1
Ball, SR; Bzdega, T; Der, EK; Farago, PR; Hark, TJ; Janczura, KJ; Lavin, KM; Lee, JC; Lee, MJ; Madore, JC; Neale, JH; Olszewski, RT; Profaci, CP1
Bacich, DJ; Bzdega, T; Heston, WD; Janczura, KJ; Neale, JH; Olszewski, RT1
Borst, P; de Haas, M; Jansen, RS; Mahakena, S; van de Wetering, K1
Balasubramanian, S; Bzdega, T; Craddock, KE; Der, EK; Hark, TJ; Janczura, KJ; Moussa, C; Neale, JH; O'Rourke, B; Olszewski, RT; Venzor, F1
Ishimura, T; Moffett, JR; Neale, JH; Nonaka, T; Yamada, T; Yamamoto, T; Zuo, D1
Barinka, C; Bím, D; Budesinsky, M; Duvall, B; Ferraris, DV; Hin, N; Kabarriti, G; Motlova, L; Novakova, Z; Rojas, C; Rokob, TA; Rulíšek, L; Slusher, BS; Tsukamoto, R; Tsukamoto, T1

Other Studies

16 other study(ies) available for urea and zj43

ArticleYear
NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR.
    Journal of neurochemistry, 2004, Volume: 89, Issue:4

    Topics: Animals; Behavior, Animal; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Male; Motor Activity; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schizophrenia; Stereotyped Behavior; Urea

2004
Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model.
    The European journal of neuroscience, 2004, Volume: 20, Issue:2

    Topics: Amino Acids; Analgesics; Animals; Behavior, Animal; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamate Carboxypeptidase II; Humans; Immunohistochemistry; Injections, Intravenous; Injections, Spinal; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Protease Inhibitors; Proto-Oncogene Proteins c-fos; Rats; Reaction Time; Sciatic Neuropathy; Urea; Xanthenes

2004
NAAG peptidase inhibitor reduces acute neuronal degeneration and astrocyte damage following lateral fluid percussion TBI in rats.
    Journal of neurotrauma, 2005, Volume: 22, Issue:2

    Topics: Animals; Astrocytes; Brain Injuries; Cell Death; Dose-Response Relationship, Drug; Glutamate Carboxypeptidase II; Male; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Urea

2005
Ketamine and N-acetylaspartylglutamate peptidase inhibitor exert analgesia in bone cancer pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:9

    Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Bone Neoplasms; Dexmedetomidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Mice; Mice, Inbred C3H; Morphine; Pain, Intractable; Protease Inhibitors; Urea

2006
Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats.
    The European journal of neuroscience, 2007, Volume: 25, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrageenan; Cells, Cultured; Cerebellum; Cricetinae; Cricetulus; Drug Interactions; Excitatory Amino Acid Agents; Formaldehyde; Functional Laterality; Glutamate Carboxypeptidase II; Neuralgia; Neurons; Organophosphorus Compounds; Pain Measurement; Pain Threshold; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Glutamate; Transfection; Urea

2007
Phencyclidine and dizocilpine induced behaviors reduced by N-acetylaspartylglutamate peptidase inhibition via metabotropic glutamate receptors.
    Biological psychiatry, 2008, Jan-01, Volume: 63, Issue:1

    Topics: Agonistic Behavior; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamate Carboxypeptidase II; Male; Mice; Phencyclidine; Receptors, Metabotropic Glutamate; Schizophrenia; Stereotyped Behavior; Urea

2008
Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain.
    Molecular pain, 2008, Aug-01, Volume: 4

    Topics: Analgesics; Animals; Dipeptides; Glutamate Carboxypeptidase II; Inflammation Mediators; Injections, Intraventricular; Male; Organophosphorus Compounds; Pain; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Urea

2008
Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model.
    Molecular pain, 2010, Sep-22, Volume: 6

    Topics: Amygdala; Animals; Behavior, Animal; Dipeptides; Disease Models, Animal; Excitatory Postsynaptic Potentials; Formaldehyde; Glutamate Carboxypeptidase II; Hyperalgesia; In Vitro Techniques; Inflammation; Mice; Models, Biological; Neuronal Plasticity; Nociceptors; Pain; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Urea

2010
Group II mGluR agonist LY354740 and NAAG peptidase inhibitor effects on prepulse inhibition in PCP and D-amphetamine models of schizophrenia.
    Psychopharmacology, 2011, Volume: 216, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamate Carboxypeptidase II; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Organophosphorus Compounds; Phencyclidine; Receptors, Metabotropic Glutamate; Reflex, Startle; Schizophrenia; Species Specificity; Urea

2011
Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-02776, in experimental TBI.
    Brain research, 2011, Jun-13, Volume: 1395

    Topics: Animals; Brain Injuries; Disease Models, Animal; Glutamate Carboxypeptidase II; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Neurotransmitter Agents; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Urea

2011
NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia.
    Translational psychiatry, 2012, Jul-31, Volume: 2

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamate Carboxypeptidase II; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recognition, Psychology; Risperidone; Schizophrenia; Soman; Urea

2012
NAAG peptidase inhibitors and deletion of NAAG peptidase gene enhance memory in novel object recognition test.
    European journal of pharmacology, 2013, Feb-15, Volume: 701, Issue:1-3

    Topics: Animals; Exploratory Behavior; Gene Deletion; Gene Knockout Techniques; Glutamate Carboxypeptidase II; Male; Memory; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Protease Inhibitors; Recognition, Psychology; Urea

2013
ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.
    The Journal of biological chemistry, 2015, Dec-18, Volume: 290, Issue:51

    Topics: Animals; Brain; Dipeptides; Humans; Kainic Acid; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nerve Tissue Proteins; Urea

2015
NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication.
    Neurochemical research, 2017, Volume: 42, Issue:9

    Topics: Alcoholic Intoxication; Alzheimer Disease; Animals; Disease Models, Animal; Ethanol; Excitatory Amino Acid Antagonists; Glutamate Carboxypeptidase II; Male; Memory; Memory Disorders; Mice; Mice, 129 Strain; Mice, Knockout; Mice, Transgenic; Motor Activity; Receptors, Metabotropic Glutamate; Urea

2017
A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA.
    Molecular pain, 2017, Volume: 13

    Topics: Analgesics; Animals; Disease Models, Animal; Dopamine beta-Hydroxylase; Excitatory Amino Acid Agents; Formaldehyde; Glutamate Carboxypeptidase II; Glutamic Acid; Locus Coeruleus; Male; Norepinephrine; Organophosphorus Compounds; Pain; Rats; Rats, Sprague-Dawley; Urea

2017
Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
    Bioorganic & medicinal chemistry, 2019, 01-15, Volume: 27, Issue:2

    Topics: Animals; Carbamates; Catalytic Domain; Cell Line; Drosophila; Enzyme Assays; Glutamate Carboxypeptidase II; Humans; Hydrogen Bonding; Models, Molecular; Protease Inhibitors; Protein Binding; Quantum Theory; Stereoisomerism; Urea

2019