urea and unbs 5162

urea has been researched along with unbs 5162 in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (16.67)	29.6817
2010's	5 (83.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bontempi, G; Bruyère, C; Darro, F; De Nève, N; Decaestecker, C; Dehoux, MJ; Dewelle, J; Haibe-Kains, B; Kiss, R; Mahieu, T; Mijatovic, T; Simon, G; van der Aar, E; Van Quaquebeke, E	1
Borad, MJ; Chalasani, P; Kurtin, S; Mahadevan, D; Northfelt, DW; Rensvold, D; Tibes, R; Von Hoff, DD	1
He, D; Zhang, S	1
Gao, Y; Liu, C; Xing, J	1
Cheng, X; Cong, J; Fan, J; Li, H; Li, Z; Shi, X; Xie, J; Yang, L; Zhao, Y	1
Liu, JM; Lv, HZ; Wang, CC; Ye, XY; Zhang, F	1

Trials

1 trial(s) available for urea and unbs 5162

Article	Year
Phase I trial of UNBS5162, a novel naphthalimide in patients with advanced solid tumors or lymphoma. International journal of clinical oncology, 2013, Volume: 18, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Animals; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lymphoma; Male; Maximum Tolerated Dose; Mice; Middle Aged; Naphthalimides; Neoplasm Metastasis; Neoplasm Staging; Rats; Urea	2013

Article

Year

Phase I trial of UNBS5162, a novel naphthalimide in patients with advanced solid tumors or lymphoma.

International journal of clinical oncology, 2013, Volume: 18, Issue:5

Topics: Adult; Aged; Aged, 80 and over; Animals; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lymphoma; Male; Maximum Tolerated Dose; Mice; Middle Aged; Naphthalimides; Neoplasm Metastasis; Neoplasm Staging; Rats; Urea

2013

Other Studies

5 other study(ies) available for urea and unbs 5162

Article	Year
UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:6 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Chemokines, CXC; Disease Models, Animal; Humans; Kinetics; Male; Mice; Naphthalimides; Neoplasm Transplantation; Prostatic Neoplasms; Urea	2008
UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. Molecular medicine reports, 2018, Volume: 17, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Naphthalimides; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction; Urea	2018
UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis. Thoracic cancer, 2018, Volume: 9, Issue:1 Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Naphthalimides; Urea	2018
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway. Molecular medicine reports, 2018, Volume: 18, Issue:3 Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Melanoma; Naphthalimides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Urea	2018
UNBS5162 inhibits colon cancer growth via suppression of PI3K/Akt signaling pathway. Medecine sciences : M/S, 2018, Volume: 34 Focus issue F1 Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Colonic Neoplasms; Down-Regulation; HCT116 Cells; Humans; Naphthalimides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Urea	2018