urea and sc 52151

urea has been researched along with sc 52151 in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bryant, ML; Clare, M; DeCrescenzo, GA; Getman, DP; Heintz, RM; Houseman, KA; Marr, JJ; Mueller, RA; Reed, KL; Talley, JJ	1
Birkmeier, J; Stolzenbach, J; Yang, DC; Yuan, J	1
Bryant, M; Clare, M; DeCrescenzo, G; Dillard, R; Getman, D; Heintz, R; Houseman, K; Lansky, D; Marr, J; Smidt, M	1
Alam, M; Bechtold, CM; Colonno, RJ; Gong, YF; Greytok, JA; Lin, PF; Robinson, BS; Rose, RE; Terry, BJ	1
Corbeil, J; Moutouh, L; Richman, DD	1
Roston, DA; Sun, JJ	1
Bold, G; Capraro, HG; Goutte, G; Klimkait, T; Lazdins, JK; Mestan, J; Walker, MR	1
Salamon, CM; Schoenhard, GL; Snook, SS; Stolzenbach, JC; Yuan, JH	1
Fischl, MA; Flexner, C; Haubrich, R; Holden-Wiltse, J; Karim, A; Meehan, PM; Para, MF; Richman, DD; Yeramian, P	1
Gold, D; Loftus, R	1

Trials

1 trial(s) available for urea and sc 52151

Article	Year
Phase I/II study of the toxicity, pharmacokinetics, and activity of the HIV protease inhibitor SC-52151. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, May-01, Volume: 15, Issue:1 Topics: Adult; CD4 Lymphocyte Count; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; RNA, Viral; Urea	1997

Article

Year

Phase I/II study of the toxicity, pharmacokinetics, and activity of the HIV protease inhibitor SC-52151.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, May-01, Volume: 15, Issue:1

Topics: Adult; CD4 Lymphocyte Count; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; RNA, Viral; Urea

1997

Other Studies

9 other study(ies) available for urea and sc 52151

Article	Year
Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere. Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2 Topics: Antiviral Agents; HIV Protease Inhibitors; Humans; Hydroxyurea; Stereoisomerism; Structure-Activity Relationship; Urea	1993
Determination of protein binding by in vitro charcoal adsorption. Journal of pharmacokinetics and biopharmaceutics, 1995, Volume: 23, Issue:1 Topics: Adsorption; Animals; Blood Proteins; Charcoal; Humans; Protein Binding; Rats; Ultrafiltration; Urea	1995
SC-52151, a novel inhibitor of the human immunodeficiency virus protease. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:10 Topics: Amino Acid Sequence; Animals; Antiviral Agents; Dogs; Drug Synergism; HIV; HIV Protease Inhibitors; Humans; Macaca mulatta; Molecular Sequence Data; Protein Binding; Rats; Rats, Sprague-Dawley; Urea; Zidovudine	1995
Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-20, Volume: 93, Issue:4 Topics: Amino Acid Sequence; Carbamates; Clone Cells; DNA Mutational Analysis; DNA, Recombinant; DNA, Viral; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ethanolamines; HeLa Cells; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Methylurea Compounds; Molecular Sequence Data; Point Mutation; Proviruses; Pyridines; Quinolines; Reassortant Viruses; Recombinant Fusion Proteins; Saquinavir; T-Lymphocytes; Urea; Valine	1996
Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure. Proceedings of the National Academy of Sciences of the United States of America, 1996, Jun-11, Volume: 93, Issue:12 Topics: Amino Acid Sequence; Base Sequence; Cell Line; Drug Resistance, Microbial; Drug Resistance, Multiple; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Serial Passage; Urea; Zidovudine	1996
Supercritical fluid extraction method development for extraction of an experimental HIV protease inhibitor drug from animal feed. Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:4 Topics: Animal Feed; Chromatography, High Pressure Liquid; Food Contamination; HIV Protease Inhibitors; Regression Analysis; Urea	1997
In vitro effect of alpha1-acid glycoprotein on the anti-human immunodeficiency virus (HIV) activity of the protease inhibitor CGP 61755: a comparative study with other relevant HIV protease inhibitors. The Journal of infectious diseases, 1997, Volume: 175, Issue:5 Topics: Anti-HIV Agents; Carbamates; Cell Line; Cells, Cultured; Ethylenes; Furans; HIV Protease Inhibitors; HIV Seronegativity; HIV-1; Humans; Indinavir; Kinetics; Lymphocytes; Orosomucoid; Ritonavir; Saquinavir; Sulfonamides; Urea; Virus Replication	1997
Improvement of bioavailability of the HIV protease inhibitor SC-52151 in the beagle dog by coadministration of the CYP3A4 inhibitor, ketoconazole. Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:5 Topics: Administration, Oral; Animals; Antifungal Agents; Biological Availability; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Synergism; Enzyme Inhibitors; Female; Half-Life; HIV Protease Inhibitors; Injections, Intravenous; Isoenzymes; Ketoconazole; Metabolic Clearance Rate; Urea	1997
Protease inhibitors: where are they now? GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1 Topics: Animals; Blood Proteins; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Industry; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Oligopeptides; Protein Binding; Pyrones; Quinolines; Rats; Saquinavir; Technology, Pharmaceutical; Urea; Warfarin; Zidovudine	1995