urea has been researched along with pyrroles in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (21.43) | 18.7374 |
| 1990's | 3 (4.29) | 18.2507 |
| 2000's | 21 (30.00) | 29.6817 |
| 2010's | 26 (37.14) | 24.3611 |
| 2020's | 5 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Crippen, GM; Ghose, AK | 1 |
| Kurelec, B | 1 |
| DeCaprio, AP; Jackowski, SJ; Regan, KA | 1 |
| Guilford, H; Scott, JE | 1 |
| Ford, EJ | 1 |
| Berliner, LJ | 1 |
| Luck, G; Zimmer, C | 1 |
| Gibson, SL; Goldberg, A; Mackenzie, JC | 1 |
| Guard-Friar, D; MacColl, R | 1 |
| Eisele, LE; MacColl, R; McNaughton, P; Williams, EC | 1 |
| Bellmunt, MJ; Bergua, M; Pamplona, R; Portero-Otín, M; Prat, J | 1 |
| Ebisu, H; Fukuda, Y; Furuta, H; Kusama, Y; Oomori, Y; Terashima, S | 1 |
| Bhargava, A; Bombara, M; Caringal, Y; Dally, R; Dumas, J; Gunn, D; Housley, TJ; Johnson, JS; Kingery-Wood, J; Lee, W; Osterhout, M; Paulsen, H; Ranges, GE; Redman, AM; Renick, J; Scott, WJ; Shrikhande, A; Smith, RA; Swartz, S; Wild, H; Wilhelm, SM; Young, D | 1 |
| Ebisu, H; Fukuda, Y; Furuta, H; Oomori, Y; Seto, S; Terashima, S | 1 |
| Decaux, G | 1 |
| Dineshkumar, TK; Subbulakshmi, C; Thanedar, S; Varshney, U | 1 |
| ASATOOR, AM; MILNE, MD; SIMENHOFF, ML; ZILVA, JF | 1 |
| FINGER, H; FRETZDORFF, AM; SCHNEIDER, F; SEYNSCHE, K; WEITZEL, G | 1 |
| OZOLS, J; STRITTMATTER, P | 1 |
| BUTLER, WL; MILLER, CO; SIEGELMAN, HW | 1 |
| HARDMAN, JK; YANOFSKY, C | 1 |
| BLACK, S; COLMAN, RF | 1 |
| Anderson, BD; Campbell, RM; Li, HY; Wagner, JR; Wang, Y; Yan, L; Yingling, JM | 1 |
| Alley, MC; Gregson, SJ; Hartley, JA; Hollingshead, MG; Howard, PW; Pacula-Cox, CM; Sausville, EA; Thurston, DE; Waud, WR | 1 |
| Böhm, S; Bubenzer, C; Scheer, H; Song, B; Su, P; Zhao, KH; Zhou, M | 1 |
| Bisht, V; Kaneto, K; Takashima, W | 1 |
| Duman, S; Oreopoulos, DG; Sen, S; Sozmen, EY | 1 |
| Aoyama, T; Ishibe, T; Katagiri, T; Nagayama, S; Nakamura, T; Nakamura, Y; Nakayama, T; Nishijo, K; Okamoto, T; Shibata, KR; Shima, Y; Toguchida, J | 1 |
| Teng, CM; Wu, CC | 1 |
| Di Serio, C; Pellerito, S; Tarantini, F | 1 |
| Boyce, S; Carlson, E; Chicchi, GG; Collinson, N; Demartino, J; Devita, RJ; Doss, G; Kurtz, MM; Lin, P; Mills, SG; Moore, S; Morriello, GJ; Rupniak, N; Townson, K; Tsao, KL; Wheeldon, A; Young, JR | 1 |
| An, Y; Borzilleri, RM; Cai, ZW; Chen, XT; Cornelius, LA; Fargnoli, J; Hunt, JT; Kamath, A; Kim, K; Lombardo, LJ; Manne, V; Marathe, P; Sack, JS; Schmidt, RJ; Schroeder, GM; Tokarski, JS; Wei, D; Williams, DK; Zhang, Y | 1 |
| Gerami, P; Guitart, J; Lacouture, ME; Reilly, LM | 1 |
| Baumgardt, I; Butenschön, H; Cao, W; Erden, I; Gärtner, C; Hoarau, C; Ozer, G; Song, J | 1 |
| Chang, YS; Syu, MJ | 1 |
| Ballester, P; Gil-Ramírez, G | 1 |
| Ballard, TE; Cavanagh, J; Mathies, LD; Melander, C; Reyes, S; Richards, JJ; Stowe, SD; Tucker, AT | 1 |
| Allen, J; Almstead, ZY; Courtney, LF; Crist, M; Crosson, CE; Gardyan, M; Gopinathan, S; Gu, KJ; Hamman, BD; Harrison, BA; Key, B; Kimball, SD; Liu, Q; Liu, Y; Mabon, R; McKnight, B; Patel, N; Rawlins, DB; Rice, DS; Voronkov, MV; Whitlock, NA; Wilson, AG; Yates, PW; Zhang, Y; Zhou, J | 1 |
| Hatanaka, M; Onitsuka, K; Sasai, H; Shinohara, T; Takenaka, K; Takizawa, S; Tsujihara, T | 1 |
| Berrendero, F; de Lecea, L; Maldonado, R; Martín-García, E; Plaza-Zabala, A | 1 |
| Chang, CN; Chen, CH; Chen, GS; Chen, YC; Chern, JW; Chou, NT; Chou, SH; Hseu, TH; Hsu, HC; Hu, TL; Huang, CH; Hwang, CS; Khanwelkar, RR; Ko, CH; Lee, O; Lin, HC; Lin, MW; Liu, CP; Shih, YC; Tsai, YJ; Tseng, HW; Tu, CM; Wang, HC; Wang, LM; Yu, CW | 1 |
| Jeong, KS; Juwarker, H | 1 |
| Awazu, Y; Hori, A; Imamura, S; Kamiyama, K; Miki, H; Miyamoto, N; Oguro, Y; Okada, K; Takagi, T | 1 |
| Chan, L; Fagnou, K; Huestis, MP; Stuart, DR | 1 |
| Dydio, P; Jurczak, J; Lichosyt, D | 1 |
| Claramunt, RM; Elguero, J; Farrán, MÁ; García, MÁ; María, DS; Pinilla, E; Torres, MR | 1 |
| Fesenko, AA; Shutalev, AD | 1 |
| Al-Dabbagh, B; Albawardi, A; Alfazari, AS; Almarzooqi, S; Souid, AK | 1 |
| Alizadeh, N; Kalhor, H | 1 |
| Laskar, MJ; Mishra, SK; Puri, N; Srivastava, AK | 1 |
| Couturier, BS; Decaux, G; Gankam Kengne, F; Soupart, A | 1 |
| Butterworth, S; Clayden, J; Tait, MB | 1 |
| Aungier, SR; Cartwright, AJ; Ito, K; Midwood, KS; To, WS | 1 |
| Gui, Y; Li, L; Shi, Z; Singh, P; Walsh, MP; Yin, H; Yu, YN; Zheng, XL; Zhou, YX | 1 |
| Azam, MA; Jubie, S; Thathan, J | 1 |
| Ding, H; Jiang, P; Li, F; Liu, Q; Wang, J; Wang, Q; Xu, Y; Yu, R | 1 |
| Crijns, HJ; De Boer, HC; De Jong, AM; Kamphuisen, PW; Kuiper, M; Lau, DH; Linz, D; Lumeij, S; Maass, AH; Rienstra, M; Schotten, U; Spronk, HM; Ten Cate, H; Van Gelder, IC; van Hunnik, A; van Zonneveld, AJ; Verheule, S; Zeemering, S | 1 |
| Huang, QY; Wang, D; Yang, F; Yang, LL; Yuan, GR; Zhou, L | 1 |
| Fujita, M; Graham, DY; Haruma, K; Ishii, M; Kamada, T; Katsumata, R; Matsumoto, H; Murao, T; Nakato, R; Shiotani, A | 1 |
| Kato, M; Mabe, K; Nakagawa, S; Ono, S; Sakamoto, N | 1 |
| Camurlu, P; Cevik, E; Dervisevic, E; Dervisevic, M; Senel, M; Yildiz, HB | 1 |
| Bakar-Ates, F; Karakas, B; Kilic-Kurt, Z; Kütük, Ö | 1 |
| Álvarez, E; Carmona, AT; Elías-Rodríguez, P; Ide, D; Kato, A; Miyawaki, S; Moreno-Vargas, AJ; Pingitore, V; Robina, I | 1 |
| Abouzid, KAM; Adel, M; Lasheen, DS; Serya, RAT | 1 |
| Blume, C; Laxa, M; Mühlenbruch, M; Ost, J; Peterhänsel, C | 1 |
| George, S; Serrano, C | 1 |
| Dong, Z; Li, J | 1 |
| Botewad, SN; Gaikwad, DK; Girhe, NB; Pawar, PP; Thorat, HN | 1 |
| Serrano, C | 1 |
| Hubbell, GE; Tepe, JJ | 1 |
6 review(s) available for urea and pyrroles
| Article | Year |
|---|---|
Anion-controlled foldamers.
Topics: Anions; Indoles; Polymers; Pyrroles; Triazoles; Urea | 2010 |
Amide- and urea-functionalized pyrroles and benzopyrroles as synthetic, neutral anion receptors.
Topics: Amides; Anions; Crystallography, X-Ray; Molecular Conformation; Pyrroles; Urea | 2011 |
Dual targeting DNA gyrase B (GyrB) and topoisomerse IV (ParE) inhibitors: A review.
Topics: Amino Acid Sequence; Aminopyridines; Anti-Bacterial Agents; Barbiturates; Benzimidazoles; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Indazoles; Isoxazoles; Morpholines; Organophosphates; Oxazolidinones; Prodrugs; Pyrazoles; Pyrroles; Pyrrolidines; Pyrrolidinones; Quinazolinones; Quinolines; Spiro Compounds; Topoisomerase II Inhibitors; Topoisomerase Inhibitors; Urea | 2015 |
Gastrointestinal Stromal Tumor: Challenges and Opportunities for a New Decade.
Topics: Apoptosis; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Molecular Targeted Therapy; Naphthyridines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines; Urea | 2020 |
Urea biosensors: A comprehensive review.
Topics: Biosensing Techniques; Humans; Nanotubes, Carbon; Polymers; Pyrroles; Urea | 2023 |
New treatments in advanced gastrointestinal stromal tumor.
Topics: Antineoplastic Agents; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Naphthyridines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrazoles; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Triazines; Urea | 2021 |
1 trial(s) available for urea and pyrroles
| Article | Year |
|---|---|
Difference in solute excretion during correction of hyponatremic patients with cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone by oral vasopressin V2 receptor antagonist VPA-985.
Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Diuresis; Humans; Hyponatremia; Inappropriate ADH Syndrome; Liver Cirrhosis; Osmolar Concentration; Potassium; Pyrroles; Sodium; Urea; Uric Acid; Water; Water-Electrolyte Balance | 2001 |
63 other study(ies) available for urea and pyrroles
| Article | Year |
|---|---|
Use of physicochemical parameters in distance geometry and related three-dimensional quantitative structure-activity relationships: a demonstration using Escherichia coli dihydrofolate reductase inhibitors.
Topics: Binding Sites; Escherichia coli; Folic Acid Antagonists; Models, Molecular; Protein Conformation; Structure-Activity Relationship | 1985 |
Catabolic path of arginine and NAD regeneration in the parasite Fasciola hepatica.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Radioisotopes; Carboxylic Acids; Cytosol; Dogs; Fasciola hepatica; Glutamates; Ketoglutaric Acids; Mitochondria; NAD; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroles; Pyruvates; Urea | 1975 |
Mechanism of formation and quantitation of imines, pyrroles, and stable nonpyrrole adducts in 2,5-hexanedione-treated protein.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Dithiothreitol; Hexanones; Imines; Ketones; Peptide Hydrolases; Proteins; Pyrroles; Sodium Dodecyl Sulfate; Urea | 1987 |
Alcian blue 8GX. Investigation of structural details using nuclear magnetic resonance and mass spectrometry.
Topics: Coloring Agents; Copper; Deuterium; Dioxins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Nitriles; Pyrroles; Staining and Labeling; Thiourea; Urea | 1972 |
Activity of gamma-glutamyl transpeptidase and other enzymes in the serum of sheep with liver or kidney damage.
Topics: Alcohol Oxidoreductases; Animals; Arginase; Aspartate Aminotransferases; Bilirubin; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Indoles; Intestine, Small; Kidney; Kidney Diseases; Ligation; Liver; Liver Diseases; Male; Mercury Poisoning; Muscles; Mycotoxins; Myocardium; Pancreas; Pyrazines; Pyrroles; Sheep; Sheep Diseases; Urea | 1974 |
Urea denaturation of active-site spin-labeled -chymotrypsin.
Topics: Binding Sites; Chymotrypsin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fluorine; Hydrogen-Ion Concentration; Organophosphorus Compounds; Piperidines; Protein Denaturation; Pyrroles; Urea | 1972 |
Stability and dissociation of the DNA complexes with distamycin A and Netropsin in the presence of organic solvents, urea and high salt concentration.
Topics: Amidines; Animals; Anti-Bacterial Agents; Cattle; Cesium; Chemical Phenomena; Chemistry; Chlorides; Circular Dichroism; Dimethyl Sulfoxide; DNA; Drug Stability; Edetic Acid; Glycols; Guanidines; Hot Temperature; Lithium; Methanol; Nucleic Acid Denaturation; Oligopeptides; Osmolar Concentration; Perchlorates; Pyrroles; Spectrophotometry, Ultraviolet; Thymus Gland; Tromethamine; Urea | 1972 |
The diagnosis of industrial lead poisoning.
Topics: Adult; Blood Cell Count; Blood Pressure Determination; Environmental Exposure; Hematocrit; Humans; Kidney Diseases; Lead; Lead Poisoning; Levulinic Acids; Male; Porphyrins; Pyrroles; Reticulocytes; Urea; Uric Acid | 1968 |
Spectroscopic properties of tetrapyrroles on denatured biliproteins.
Topics: Chemical Phenomena; Chemistry; Mercaptoethanol; Phycocyanin; Phycoerythrin; Pigments, Biological; Protein Denaturation; Pyrroles; Spectrophotometry; Tetrapyrroles; Urea | 1984 |
Chromophore topography and exciton splitting in phycocyanin 645.
Topics: Circular Dichroism; Eukaryota; Light-Harvesting Protein Complexes; Models, Chemical; Peptides; Phycobilins; Phycocyanin; Plant Proteins; Protein Conformation; Pyrroles; Tetrapyrroles; Urea | 1994 |
Glycaemic control and in vivo non-oxidative Maillard reaction: urinary excretion of pyrraline in diabetes patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Child; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus, Type 1; Female; Fructosamine; Glycated Hemoglobin; Humans; Maillard Reaction; Male; Matched-Pair Analysis; Middle Aged; Norleucine; Pyrroles; Regression Analysis; Urea | 1997 |
The novel cyclopropapyrroloindole(CPI) bisalkylators bearing methoxycarbonyl and trifluoromethyl groups.
Topics: Animals; Antineoplastic Agents, Alkylating; Drug Screening Assays, Antitumor; Duocarmycins; HeLa Cells; Humans; Indoles; Inhibitory Concentration 50; Mice; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured; Urea | 1998 |
p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.
Topics: Arthritis; Enzyme Inhibitors; Furans; Humans; Inhibitory Concentration 50; Interleukin-6; Mitogen-Activated Protein Kinases; Molecular Structure; Osteoporosis; p38 Mitogen-Activated Protein Kinases; Pyrroles; Thiophenes; Tumor Cells, Cultured; Urea | 2001 |
Novel seco cyclopropa[c]pyrrolo[3,2-e]indole bisalkylators bearing a 3,3'-arylenebisacryloyl group as a linker.
Topics: Animals; Antineoplastic Agents, Alkylating; Benzylidene Compounds; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Inhibitory Concentration 50; Mice; Mice, Nude; Pyrroles; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured; Urea | 2001 |
An unexpected absence of queuosine modification in the tRNAs of an Escherichia coli B strain.
Topics: Electrophoresis, Polyacrylamide Gel; Escherichia coli; Nucleoside Q; Pentosyltransferases; Pyrimidinones; Pyrroles; RNA, Bacterial; RNA, Transfer, Tyr; Urea | 2002 |
RETENTION OF ALIPHATIC AMINES IN URAEMIA.
Topics: Amines; Ammonia; Blood; Body Fluids; Cerebrospinal Fluid; Chromatography; Dinitrophenols; Geriatrics; Humans; Piperidines; Pyrroles; Urea; Uremia; Urine; Urologic Diseases | 1963 |
[ADDITIONAL CLASSES OF COMPOUNDS INHIBITING TUMORS. I. CYTOSTATIC EFFECTS OF N- AND S-HYDROXYMETHYL COMPOUNDS].
Topics: Amides; Animals; Antineoplastic Agents; Benzimidazoles; Carbohydrate Metabolism; Carcinoma, Ehrlich Tumor; Cytostatic Agents; Formaldehyde; Hydantoins; Imidazoles; Isonicotinic Acids; Mice; Morpholines; Neoplasms, Experimental; Niacin; Niacinamide; Piperazines; Piperidines; Pyrroles; Research; Urea | 1963 |
THE INTERACTION OF PORPHYRINS AND METALLOPORHYRINS WITH APOCYTOCHROME BETA-5.
Topics: Chemical Phenomena; Chemistry; Chromatography; Cobalt; Copper; Cytochromes; Deuterium; Heme; Hydrogen-Ion Concentration; Magnesium; Nickel; Porphyrins; Pyrroles; Research; Spectrophotometry; Trypsin; Urea | 1964 |
DENATURATION OF PHYTOCHROME.
Topics: Benzoates; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Ethylmaleimide; Light; Peptide Hydrolases; Phytochrome; Pigments, Biological; Pyrroles; Research; Retinal Pigments; Spectrophotometry; Trypsin; Urea | 1964 |
STUDIES ON THE ACTIVE SITE OF THE A PROTEIN SUBUNIT OF THE ESCHERICHIA COLI TRYPTOPHAN SYNTHETASE.
Topics: Bacterial Proteins; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Catalysis; Catalytic Domain; Cysteine; Enzyme Inhibitors; Escherichia coli; Ethylmaleimide; Histidine; Hydro-Lyases; Iodoacetates; Kinetics; Light; Methionine; Molecular Biology; Protein Subunits; Pyrroles; Research; Tryptophan Synthase; Urea | 1965 |
ON THE ROLE OF FLAVIN ADENINE DINUCLEOTIDE AND THIOL GROUPS IN THE CATALYTIC MECHANISM OF YEAST GLUTATHIONE REDUCTASE.
Topics: Carbon Isotopes; Catalysis; Electrophoresis; Ethylmaleimide; Flavin-Adenine Dinucleotide; Glutathione Reductase; Mercaptoethanol; Molecular Weight; NADP; Pyrroles; Radiometry; Research; Spectrophotometry; Sulfhydryl Compounds; Sulfites; Ultracentrifugation; Urea | 1965 |
Novel and potent transforming growth factor beta type I receptor kinase domain inhibitor: 7-amino 4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolines.
Topics: Activin Receptors, Type I; Cells, Cultured; Dimerization; Humans; Inhibitory Concentration 50; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyrazoles; Pyrroles; Quinolines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Structure-Activity Relationship; Urea | 2004 |
SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 2: efficacy evaluations.
Topics: Animals; Antineoplastic Agents; Benzodiazepines; Benzodiazepinones; Cell Line, Tumor; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Mice; Mice, Nude; Pyrroles; Rats; Rats, Nude; Urea; Xenograft Model Antitumor Assays | 2004 |
Reconstitution of phycobilisome core-membrane linker, LCM, by autocatalytic chromophore binding to ApcE.
Topics: Apoproteins; Bacterial Proteins; Chromatography, Affinity; Cyanobacteria; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Light-Harvesting Protein Complexes; Phycobilins; Phycobilisomes; Phycocyanin; Plasmids; Polymerase Chain Reaction; Pyrroles; Spectrometry, Fluorescence; Tetrapyrroles; Transformation, Genetic; Urea | 2005 |
An amperometric urea biosensor based on covalent immobilization of urease onto an electrochemically prepared copolymer poly (N-3-aminopropyl pyrrole-co-pyrrole) film.
Topics: Adsorption; Biosensing Techniques; Coated Materials, Biocompatible; Electrochemistry; Electrodes; Enzyme Activation; Enzyme Stability; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Feasibility Studies; Materials Testing; Polymers; Protein Binding; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Solutions; Urea; Urease; Water | 2005 |
Atorvastatin improves peritoneal sclerosis induced by hypertonic PD solution in rats.
Topics: Animals; Atorvastatin; Cholesterol; Glucose; Glucose Solution, Hypertonic; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Microscopy; Peritoneum; Pyrroles; Rats; Rats, Wistar; Sclerosis; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ultrafiltration; Urea; Vascular Endothelial Growth Factor A | 2005 |
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Isoforms; Pyrimidines; Pyrroles; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma, Synovial; Signal Transduction; Urea; Xenograft Model Antitumor Assays | 2005 |
Comparison of the effects of PAR1 antagonists, PAR4 antagonists, and their combinations on thrombin-induced human platelet activation.
Topics: Blood Platelets; Crotalid Venoms; Dose-Response Relationship, Drug; Drug Synergism; Humans; In Vitro Techniques; Indazoles; Oligopeptides; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Pyrroles; Quinazolines; Receptor, PAR-1; Receptors, Thrombin; Thrombin; Urea | 2006 |
Comments on "Blockade of angiogenesis by small molecule antagonists to protease-activated receptor-1: association with endothelial cell growth suppression and induction of apoptosis".
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line; Cell Proliferation; Chick Embryo; Endothelial Cells; Humans; Indazoles; Neovascularization, Physiologic; Pyrroles; Quinazolines; Receptor, PAR-1; Urea | 2008 |
Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists.
Topics: Amides; Bridged Bicyclo Compounds, Heterocyclic; Epoxy Compounds; Humans; Hydroxylation; Methylation; Molecular Structure; Neurokinin-1 Receptor Antagonists; Pyrroles; Receptors, Neurokinin-1; Stereoisomerism; Urea | 2008 |
Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors.
Topics: Aminopyridines; Animals; Humans; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyrroles; Stomach Neoplasms; Structure-Activity Relationship; Urea; Xenograft Model Antitumor Assays | 2008 |
Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib.
Topics: Administration, Topical; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Female; Fluorouracil; Foot Dermatoses; Hand Dermatoses; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Male; Middle Aged; Niacinamide; Nicotinic Acids; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Urea | 2008 |
Photooxygenation of 5-dialkylamino-4-pyrrolin-3-ones. Synthesis of highly functionalized ureas, 2-oxazolidinones, and 2-oxazolinones.
Topics: Acetates; Alkanes; Alkynes; Amidines; Amines; Catalysis; Cyclization; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Hydrogenation; Methanol; Models, Chemical; Oxazoles; Oxazolidinones; Oxygen; Photochemistry; Pyrroles; Solvents; Urea | 2008 |
Ionic effect investigation of a potentiometric sensor for urea and surface morphology observation of entrapped urease/polypyrrole matrix.
Topics: Biosensing Techniques; Carbon; Electrochemistry; Electrodes; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Ions; Paper; Polymers; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Surface Properties; Urea; Urease | 2009 |
Molecular recognition and self-assembly special feature: Self-assembly of dimeric tetraurea calix[4]pyrrole capsules.
Topics: Calixarenes; Dimerization; Hydrogen Bonding; Ketones; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Oxides; Porphyrins; Pyrroles; Thermodynamics; Urea; X-Ray Diffraction | 2009 |
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity.
Topics: Amides; Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Pseudomonas aeruginosa; Pyrroles; Structure-Activity Relationship; Sulfonamides; Thiourea; Urea | 2009 |
Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Glaucoma; Guanidines; In Vitro Techniques; Intraocular Pressure; Lim Kinases; Mice; Nitriles; Ocular Hypertension; Piperazines; Pyrimidines; Pyrroles; Structure-Activity Relationship; Swine; Urea | 2009 |
Enantioselective intramolecular oxidative aminocarbonylation of alkenylureas catalyzed by palladium-spiro bis(isoxazoline) complexes.
Topics: Alkenes; Amination; Catalysis; Isoxazoles; Ligands; Models, Chemical; Organometallic Compounds; Oxidation-Reduction; Palladium; Pyrimidines; Pyrroles; Spiro Compounds; Stereoisomerism; Urea | 2009 |
Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior.
Topics: Animals; Anxiety; Arginine Vasopressin; Behavior, Addictive; Benzoxazoles; Conditioning, Operant; Corticotropin-Releasing Hormone; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthyridines; Neurons; Neuropeptides; Nicotine; Orexin Receptors; Orexins; Paraventricular Hypothalamic Nucleus; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Self Administration; Tobacco Use Disorder; Urea | 2010 |
Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.
Topics: Animals; Aurora Kinases; Binding Sites; Cell Line, Tumor; Computer Simulation; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Indoles; Leukemia, Myeloid; Mice; Oxindoles; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrroles; Receptors, Platelet-Derived Growth Factor; Structure-Activity Relationship; Transplantation, Heterologous; Urea | 2010 |
N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases.
Topics: Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Computer Simulation; Crystallography, X-Ray; Drug Design; Humans; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, TIE-2; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Structure-Activity Relationship; Urea | 2010 |
The vinyl moiety as a handle for regiocontrol in the preparation of unsymmetrical 2,3-aliphatic-substituted indoles and pyrroles.
Topics: Acetamides; Catalysis; Indoles; Oxidation-Reduction; Pyrroles; Rhodium; Stereoisomerism; Urea; Vinyl Compounds | 2011 |
Synthetic hosts for molecular recognition of ureas.
Topics: Biotin; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Conformation; Monte Carlo Method; Pyridines; Pyrroles; Urea | 2011 |
Synthesis of γ-azido-β-ureido ketones and their transformation into functionalized pyrrolines and pyrroles via Staudinger/aza-Wittig reaction.
Topics: Azides; Carboxylic Acids; Ketones; Molecular Structure; Pyrroles; Urea | 2013 |
Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin.
Topics: Adenosine Triphosphate; Animals; Atorvastatin; Caspases; Energy Metabolism; Hepatocytes; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Oxygen; Pyrroles; Urea | 2013 |
Determining urea levels in dialysis human serum by means of headspace solid phase microextraction coupled with ion mobility spectrometry and on the basis of nanostructured polypyrrole film.
Topics: Humans; Membranes, Artificial; Microscopy, Electron, Scanning; Molecular Imprinting; Nanostructures; Polymers; Pyrroles; Solid Phase Microextraction; Spectrum Analysis; Urea; Urease; Water | 2013 |
Microstructural and potential dependence studies of urease-immobilized gold nanoparticles-polypyrrole composite film for urea detection.
Topics: Ascorbic Acid; Dielectric Spectroscopy; Electrochemical Techniques; Electrodes; Enzymes, Immobilized; Glass; Gold; Hydrogen-Ion Concentration; Metal Nanoparticles; Microscopy, Atomic Force; Polymers; Potentiometry; Pyrroles; Recycling; Spectroscopy, Fourier Transform Infrared; Surface Properties; Temperature; Tin Compounds; Urea; Urease | 2014 |
Urea minimizes brain complications following rapid correction of chronic hyponatremia compared with vasopressin antagonist or hypertonic saline.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Astrocytes; Benzamides; Blood-Brain Barrier; Brain Diseases; Chronic Disease; Demyelinating Diseases; Hyponatremia; Male; Microglia; Pyrroles; Rats; Rats, Wistar; Saline Solution, Hypertonic; Urea | 2015 |
2,2- and 2,6-Diarylpiperidines by aryl migration within lithiated urea derivatives of tetrahydropyridines.
Topics: Cyclization; Lithium; Molecular Structure; Piperidines; Pyridines; Pyrroles; Urea | 2015 |
Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells.
Topics: Acetamides; Adalimumab; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dasatinib; Dose-Response Relationship, Drug; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Macrophages; Monocytes; Naphthalenes; Oxazines; Piperidines; Primary Cell Culture; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; RNA, Small Interfering; Signal Transduction; Synovial Membrane; Tumor Necrosis Factor-alpha; Urea | 2015 |
Potential Role of Glycogen Synthase Kinase-3β in Regulation of Myocardin Activity in Human Vascular Smooth Muscle Cells.
Topics: Actins; Calcium-Binding Proteins; Calponins; Cell Differentiation; Cell Line; Gene Expression Regulation; Gene Knockout Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Membrane Proteins; Microfilament Proteins; Muscle Proteins; Myocytes, Smooth Muscle; Nuclear Proteins; Phosphoproteins; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Recombinant Proteins; RNA, Small Interfering; Serine; Thiazoles; Threonine; Trans-Activators; Urea | 2016 |
Aromaticity-Dependent Regioselectivity in Pd(II)-Catalyzed C-H Direct Arylation of Aryl Ureas.
Topics: Catalysis; Combinatorial Chemistry Techniques; Indoles; Molecular Structure; Naphthalenes; Palladium; Pyrroles; Stereoisomerism; Urea | 2015 |
Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation.
Topics: Analysis of Variance; Animals; Antithrombins; Atrial Fibrillation; Cell Proliferation; Dabigatran; Female; Fibrinolytic Agents; Fibroblasts; Fibrosis; Goats; Heart Atria; Indazoles; Mice, Transgenic; Nadroparin; Peptide Hydrolases; Pyrroles; Quinazolines; Rats; Receptors, Thrombin; Thrombin; Thrombophilia; Urea | 2017 |
Suppression of TRPV4 channels ameliorates anti-dipsogenic effects under hypoxia in the subfornical organ of rats.
Topics: Animals; Calcium; Cell Line; Drinking; Gadolinium; HEK293 Cells; Heme Oxygenase (Decyclizing); Humans; Hydrogen-Ion Concentration; Hypoxia; Male; Morpholines; Neurons; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium; Subfornical Organ; Temperature; TRPV Cation Channels; Urea | 2016 |
Helicobacter pylori Eradication with Proton Pump Inhibitors or Potassium-Competitive Acid Blockers: The Effect of Clarithromycin Resistance.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Carbon Isotopes; Clarithromycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer; Polymerase Chain Reaction; Proton Pump Inhibitors; Pyrroles; Retrospective Studies; RNA, Ribosomal, 23S; Sulfonamides; Treatment Outcome; Urea | 2016 |
Vonoprazan improves the efficacy of Helicobacter pylori eradication therapy with a regimen consisting of clarithromycin and metronidazole in patients allergic to penicillin.
Topics: Anti-Bacterial Agents; Breath Tests; Carbon Isotopes; Clarithromycin; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hypersensitivity; Male; Metronidazole; Middle Aged; Pyrroles; Retrospective Studies; Sulfonamides; Treatment Outcome; Urea | 2017 |
Construction of ferrocene modified conducting polymer based amperometric urea biosensor.
Topics: Aniline Compounds; Biosensing Techniques; Electric Conductivity; Electrochemical Techniques; Enzymes, Immobilized; Ferrous Compounds; Humans; Metallocenes; Polymers; Pyrroles; Thiophenes; Urea; Urease | 2017 |
Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrimidines; Pyrroles; Structure-Activity Relationship; Urea | 2018 |
Discovery of a Potent α-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine-(Thio)urea Hybrid Molecules Generated via Click Chemistry.
Topics: alpha-Galactosidase; Click Chemistry; Drug Discovery; Enzyme Inhibitors; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Pyrroles; Structure-Activity Relationship; Urea | 2018 |
Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Human Umbilical Vein Endothelial Cells; Humans; Models, Molecular; Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Urea; Vascular Endothelial Growth Factor Receptor-2 | 2018 |
Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Biosynthetic Pathways; Carbon Dioxide; Citrulline; Gene Expression Regulation, Plant; Genes, Plant; Light; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; RNA, Plant; Stress, Physiological; Sucrose; Urea | 2019 |
[Current status and progress in novel drug research for gastrointestinal stromal tumors].
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Naphthyridines; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Triazines; Urea | 2020 |
Rh(III)-Catalyzed C-H Activation/Annulation of Benzohydroxamates and 2-Imidazolones: Access to Urea-Fused-Dihydroisoquinolone Scaffolds Reminiscent of Pyrrole Alkaloid Natural Products.
Topics: Alkaloids; Alkenes; Biological Products; Catalysis; Cyclization; Imidazoles; Pyrroles; Rhodium; Urea | 2022 |