urea has been researched along with pyrazole in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| FOLEY, HT; GOLD, GL; SHNIDER, BI; UZER, Y | 1 |
| Kirby, GM; Nichols, KD | 1 |
| Chen, Y; Tian, G; Ye, X; Yu, Q; Zhang, Z | 1 |
| Adams, JW; Casper, M; Choi, K; Decaire, M; Dosa, PI; Elwell, K; Jayakumar, H; Lehmann, J; Ramirez, J; Richman, JG; Semple, G; Strah-Pleynet, S; Teegarden, BR; Thomsen, W; Webb, RR; Wong, A; Xiong, Y | 1 |
| Bergman, LW; Daly, T; Ejigiri, I; Kortagere, S; Morrisey, JM; Sinnis, P; Vaidya, AB; Welsh, WJ | 1 |
| Ben-Hassine, M; Braun, A; Crespin, O; Dadji-Faïhun, R; Engel, C; Farjot, G; Güssregen, S; Leger, C; Maniani, K; Monseau, C; Mougenot, C; Mougenot, P; Namane, C; Nicolaï, E; Noah, L; Onofri, B; Pacquet, F; Pascal, C; Philippo, C; Ragot, JL; Van-Pham, T; Venier, O | 1 |
| Brenk, R; Cleghorn, LA; Collie, IT; Frearson, JA; Gilbert, IH; Luksch, T; Mottram, JC; Mpamhanga, C; Norcross, N; Torrie, LS; Walker, RG; Woodland, A; Wyatt, PG | 1 |
| Aoki, T; Arai, T; Hayashi, S; Hirokawa, H; Inoue, H; Kainoh, M; Kawai, H; Koga, Y; Meguro, H; Ohno, M; Oshida, K; Suyama, K | 1 |
| Hatnapure, GD; Kamble, VM; Keche, AP; Rodge, AH; Tale, RH | 1 |
| Guruvayoorappan, C; Kannan, N; Prabhu, VV | 1 |
| Castaldo, C; Comery, TA; Dunlop, J; Genesio, E; Ghiron, C; Haydar, S; Maccari, L; Micco, I; Nencini, A; Turlizzi, E; Zanaletti, R; Zhang, J | 1 |
| Lindsley, CW; Weaver, CD; Wen, W; Wu, W | 1 |
| Boerth, JA; Ellman, JA | 1 |
| El-Dash, Y; Gedawy, EM; Kassab, AE | 1 |
| Brullo, C; Bruno, O; Rapetti, F | 1 |
| Belvedere, R; Brullo, C; Bruno, O; Monti, MC; Morretta, E; Petrella, A; Rapetti, F; Spallarossa, A | 1 |
1 review(s) available for urea and pyrazole
| Article | Year |
|---|---|
Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry.
Topics: Chemistry Techniques, Synthetic; Chemistry, Pharmaceutical; Humans; Pharmaceutical Preparations; Pyrazoles; Structure-Activity Relationship; Urea | 2020 |
15 other study(ies) available for urea and pyrazole
| Article | Year |
|---|---|
PHASE I STUDIES OF PYRAZOLE (NSC-45410).
Topics: Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Blood; Blood Urea Nitrogen; Drug Therapy; Leukopenia; Mice; Pyrazoles; Thrombocytopenia; Toxicology; Urea; Vomiting | 1965 |
Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: identification of potential stimuli of Cyp2a5 induction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bilirubin; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Endoplasmic Reticulum; Enzyme Induction; Gene Expression Regulation; Glucose; Homeostasis; Liver; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Nitrogen; Oligonucleotide Array Sequence Analysis; Pyrazoles; Urea | 2008 |
Influences of nitrification inhibitor 3,4-dimethyl pyrazole phosphate on nitrogen and soil salt-ion leaching.
Topics: Fertilizers; Nitrates; Nitrogen; Pyrazoles; Soil; Urea; Water Pollutants, Chemical; Water Pollution | 2008 |
Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents.
Topics: Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Structure-Activity Relationship; Urea | 2009 |
Structure-based design of novel small-molecule inhibitors of Plasmodium falciparum.
Topics: Antimalarials; Crystallography, X-Ray; Drug Design; Humans; Malaria, Falciparum; Models, Molecular; Nonmuscle Myosin Type IIA; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Pyrazoles; Small Molecule Libraries; Urea | 2010 |
Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11β-hydroxysteroid-dehydrogenase type 1.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Administration, Oral; Animals; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Mice; Pyrazoles; Pyrrolidines; Urea | 2011 |
Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3.
Topics: Binding Sites; CDC2 Protein Kinase; Computer Simulation; Drug Evaluation, Preclinical; Humans; Leishmania; Leishmaniasis; Protein Kinase Inhibitors; Protein Structure, Tertiary; Protozoan Proteins; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Urea | 2011 |
Design and synthesis of novel p38α MAP kinase inhibitors: discovery of pyrazole-benzyl ureas bearing 2-molpholinopyrimidine moiety.
Topics: Administration, Oral; Animals; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Lipopolysaccharides; Liver; Mice; Mitogen-Activated Protein Kinase 14; Naphthalenes; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrazoles; Pyridines; Pyrimidines; Tumor Necrosis Factor-alpha; Urea | 2012 |
Synthesis, anti-inflammatory and antimicrobial evaluation of novel 1-acetyl-3,5-diaryl-4,5-dihydro (1H) pyrazole derivatives bearing urea, thiourea and sulfonamide moieties.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Thiourea; Urea | 2012 |
1,2-Diazole prevents cisplatin-induced nephrotoxicity in experimental rats.
Topics: Animals; Antioxidants; Cisplatin; Creatinine; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Pyrazoles; Rats; Silymarin; Urea; Urine | 2013 |
Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Membrane Permeability; Dogs; Dose-Response Relationship, Drug; Drug Design; Humans; Male; Models, Molecular; Molecular Structure; Pyrazoles; Rats; Rats, Wistar; Structure-Activity Relationship; Urea | 2014 |
Discovery of potent and selective GIRK1/2 modulators via 'molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas.
Topics: Animals; Drug Evaluation, Preclinical; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Microsomes; Phenylurea Compounds; Protein Binding; Pyrazoles; Rats; Structure-Activity Relationship; Urea | 2014 |
A Convergent Synthesis of Functionalized Alkenyl Halides through Cobalt(III)-Catalyzed Three-Component C-H Bond Addition.
Topics: Amides; Catalysis; Cobalt; Hydrocarbons, Halogenated; Molecular Structure; Pyrazoles; Urea | 2017 |
Novel pyrazolopyrimidine urea derivatives: Synthesis, antiproliferative activity, VEGFR-2 inhibition, and effects on the cell cycle profile.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Urea; Vascular Endothelial Growth Factor Receptor-2 | 2020 |
Novel insights on the molecular mechanism of action of the anti-angiogenic pyrazolyl-urea GeGe-3 by functional proteomics.
Topics: Angiogenesis Inhibitors; Binding Sites; Calcium; Calreticulin; Down-Regulation; Focal Adhesion Kinase 1; Human Umbilical Vein Endothelial Cells; Humans; Ionomycin; Molecular Docking Simulation; Proteome; Proteomics; Pyrazoles; Urea | 2021 |