Compounds > urea

urea and pd 166866

urea has been researched along with pd 166866 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's7 (70.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batley, BL; Brown, KJ; Connolly, C; Dahring, TK; Hamby, JM; Lu, GH; Panek, RL1
Barnard, JC; Brady, G; Chassande, O; Harvey, CB; O'Shea, PJ; Samarut, J; Scott, AJ; Stevens, DA; Williams, AJ; Williams, GR1
Barbeito, AG; Barbeito, L; Beckman, JS; Cassina, P; Castellanos, R; Estévez, AG; Pehar, M; Thompson, JA; Vargas, MR1
Aoyama, T; Ishibe, T; Katagiri, T; Nagayama, S; Nakamura, T; Nakamura, Y; Nakayama, T; Nishijo, K; Okamoto, T; Shibata, KR; Shima, Y; Toguchida, J1
Barbeito, L; Beckman, JS; Cassina, P; Pehar, M; Vargas, MR1
Borioni, A; Del Giudice, MR; Delfini, M; Mustazza, C; Piccioni, F; Risuleo, G; Rodomonte, A1
Calandrella, N; Castelli, M; Galati, F; Galati, G; Giuliani, A; Mustazza, C; Risuleo, G; Scarsella, G1
Castelli, M; Ciacciarelli, M; Galati, G; Risuleo, G1
Berger, W; Grusch, M; Hauck, M; Holzmann, K; Kleiter, M; Kreilmeier, T; Marian, B; Reifinger, M; Sampl, S; Schweiger, N; Steinhoff, H; Walter, I1
Chen, Y; Cheng, Z; Jing, Q; Li, G; Li, J; Li, X; Liu, R; Liu, Y; Song, H; Wang, J; Wang, P; Xie, X; Yue, J1

Other Studies

10 other study(ies) available for urea and pd 166866

ArticleYear
In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: 3T3 Cells; Animals; Fibroblast Growth Factors; Humans; In Vitro Techniques; Mice; Neovascularization, Physiologic; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Urea

1998
Thyroid hormone activates fibroblast growth factor receptor-1 in bone.
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:9

    Topics: Animals; Bone and Bones; Fibroblast Growth Factor 2; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphorylation; Phosphotransferases; Pyrimidines; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; Thyroid Gland; Triiodothyronine; Urea

2003
Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
    Journal of neurochemistry, 2005, Volume: 93, Issue:1

    Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspase 3; Cell Count; Cells, Cultured; Coculture Techniques; Embryo, Mammalian; Fibroblast Growth Factor 1; Fluorescent Antibody Technique; Free Radical Scavengers; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Metalloporphyrins; Mice; Mice, Transgenic; Motor Neurons; Nerve Growth Factor; Protein-Tyrosine Kinases; Pyrimidines; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Nerve Growth Factor; RNA, Messenger; Spinal Cord; Superoxide Dismutase; Tyrosine; Urea

2005
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-01, Volume: 11, Issue:7

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Isoforms; Pyrimidines; Pyrroles; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma, Synovial; Signal Transduction; Urea; Xenograft Model Antitumor Assays

2005
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis.
    Journal of neurochemistry, 2006, Volume: 97, Issue:3

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Antioxidants; Astrocytes; Blotting, Western; Cell Count; Cell Survival; Cells, Cultured; Coculture Techniques; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Fibroblast Growth Factor 1; Glial Fibrillary Acidic Protein; Glutathione; Hydroquinones; Methionine; Motor Neurons; Nerve Growth Factor; NF-E2-Related Factor 2; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Propionates; Pyrimidines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Superoxide Dismutase; Transfection; Urea

2006
Metabolic alterations in cultured mouse fibroblasts induced by an inhibitor of the tyrosine kinase receptor Fibroblast Growth Factor Receptor 1.
    Analytical biochemistry, 2007, Aug-01, Volume: 367, Issue:1

    Topics: Amino Acids; Animals; Cell Line; Dimethyl Sulfoxide; Enzyme Inhibitors; Mice; Nuclear Magnetic Resonance, Biomolecular; Nucleotides; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Urea

2007
Reduction of cell proliferation induced by PD166866: an inhibitor of the basic fibroblast growth factor.
    Journal of experimental & clinical cancer research : CR, 2007, Volume: 26, Issue:3

    Topics: Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; Fibroblast Growth Factor 2; Fluorescent Antibody Technique; In Situ Nick-End Labeling; Mice; Proliferating Cell Nuclear Antigen; Pyrimidines; Urea

2007
The synthetic inhibitor of fibroblast growth factor receptor PD166866 controls negatively the growth of tumor cells in culture.
    Journal of experimental & clinical cancer research : CR, 2009, Dec-11, Volume: 28

    Topics: Cell Growth Processes; Cell Line, Tumor; Cell Survival; DNA Damage; HeLa Cells; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Pyrimidines; Receptors, Fibroblast Growth Factor; Urea

2009
Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:9

    Topics: Animals; Cell Line, Tumor; Dogs; Gene Expression Regulation, Neoplastic; Humans; Protein Isoforms; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Sarcoma; Signal Transduction; Urea

2015
FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell.
    Biochemical and biophysical research communications, 2016, 05-20, Volume: 474, Issue:1

    Topics: Animals; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome; Urea

2016