urea has been researched along with oxadiazoles in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (31.58) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Craig, JW; Reed, SE; Tyrrell, DA | 1 |
| Arihara, S; Koike, K; Nakajima, T; Takemoto, T | 1 |
| Amico Roxas, M; Caruso, A; Corsaro, A; Leone, MG; Mazzone, G; Panico, AM; Pignatello, R; Puglisi, G | 1 |
| Dorough, HW | 1 |
| Weber, RO; Zinner, G | 1 |
| Nebel, G; Zinner, G | 1 |
| Bauer, PM; Buga, GM; Fukuto, JM; Ignarro, LJ; Wei, LH | 1 |
| Brown, T; Bunton, D; MacDonald, A; McGrath, JC; Shaw, AM; Tracey, A | 1 |
| Chang, DI; Hwang, SJ; Kim, SH; Koh, SH; Yoo, AR | 1 |
| Ke, S; Li, Z; Qian, X | 1 |
| Chiyo, N; Kusunose, N; Mimoto, T; Nishimura, T; Sawada, N; Shiyama, T; Tanaka, D; Tominaga, Y; Tsuda, Y | 1 |
| D'Anna, F; Frenna, V; Ghelfi, F; Marullo, S; Spinelli, D | 1 |
| Brahma, MK; Deshmukh, NJ; Dixit, A; Doshi, L; Enose, AA; Gangopadhyay, AK; Guha, T; Gupte, A; Jadhav, RD; Kadam, KS; Kandre, S; Nemmani, KV; Potdar, N; Reddy, MM; Sharma, R; Sivaramakrishnan, H; Srinivasan, S; Vishwakarma, RA | 1 |
| Beller, A; Hoenke, C; Isambert, T; Lessel, U; Nosse, B; Wellenzohn, B | 1 |
| Arslan, M; Arslan, O; Celik, F; Gencer, N; Kaya, MO; Yavuz, E | 1 |
| Abdel-Maksoud, MS; El-Gamal, MI; Gamal El-Din, MM; Oh, CH; Yoo, KH | 1 |
| Benetti, E; Chegaev, K; Chiazza, F; Collino, M; Cutrin, JC; Fruttero, R; Lazzarato, L; Rogazzo, M | 1 |
| Jaswal, S; Kumar, S; Monga, V; Rulhania, S | 1 |
| Jiang, S; Tang, H; Wang, K; Wang, L; Wang, T; Ye, K; Zhang, K; Zhang, W; Zhang, X | 1 |
1 review(s) available for urea and oxadiazoles
| Article | Year |
|---|---|
Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors.
Topics: Acetazolamide; Animals; Antineoplastic Agents; Antioxidants; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Indoles; Isatin; Molecular Docking Simulation; Organoselenium Compounds; Oxadiazoles; Protein Binding; Protein Isoforms; Pyrimidines; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes; Urea | 2021 |
1 trial(s) available for urea and oxadiazoles
| Article | Year |
|---|---|
Four compounds active against rhinovirus: comparison in vitro and in volunteers.
Topics: Adolescent; Adult; Antiviral Agents; Cell Line; Clinical Trials as Topic; Female; HeLa Cells; Humans; In Vitro Techniques; Male; Middle Aged; Oxadiazoles; Respiratory Tract Infections; Rhinovirus; Thiazoles; Urea; Virus Diseases | 1976 |
17 other study(ies) available for urea and oxadiazoles
| Article | Year |
|---|---|
[Studies on the constituents of Quisqualis fructus. III. synthesis of quisqualic acid and the related compounds (author's transl)].
Topics: Alanine; Oxadiazoles; Plants, Medicinal; Urea | 1975 |
Synthesis and biological activity of acetamides, arylureas and 2-alkoxyphenyl-6-phenyl-1,3,4-oxa(thia)diazole-[3,2-a]-S- triazin-5,7-diones derived from 2-amino-5-alkoxyphenyl-1,3,4-oxa(thia)diazole.
Topics: Acetamides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Lethal Dose 50; Male; Mice; Oxadiazoles; Rats; Rats, Inbred Strains; Reaction Time; Spectrophotometry, Infrared; Stomach Ulcer; Thiadiazoles; Triazines; Urea | 1987 |
Metabolism of methazole in wheat and onions.
Topics: Carbon Radioisotopes; Chlorobenzenes; Chromatography, Thin Layer; Herbicides; Methanol; Methylurea Compounds; Oxadiazoles; Pesticide Residues; Plants; Solvents; Time Factors; Triticum; Urea | 1974 |
[Syntheses in the series of 3,5-dioxo-1,2,4-oxadiazolidines. 3. 19. On hydroxylamine derivatives].
Topics: Chemical Phenomena; Chemistry; Hydroxylamines; Oxadiazoles; Urea | 1965 |
[Carbonic acid-alkylester-amidoxime (N-hydroxy-O-alkyl-isourea). 42. Hydroxylamine derivatives].
Topics: Carbon Dioxide; Chemistry, Pharmaceutical; Esters; Hydroxylamines; Oxadiazoles; Oximes; Urea | 1970 |
NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
Topics: Animals; Aorta; Arginase; Arginine; Caco-2 Cells; Cell Division; Coculture Techniques; DNA; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Donors; Ornithine; Ornithine Decarboxylase; Oxadiazoles; Polyamines; Putrescine; Quinoxalines; Rats; Spermidine; Spermine; Thymidine; Triazenes; Urea | 1998 |
5-hydroxytryptamine- and U46619-mediated vasoconstriction in bovine pulmonary conventional and supernumerary arteries: effect of endogenous nitric oxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Serotonin; Serotonin Antagonists; Urea; Vasoconstrictor Agents | 2000 |
Inhibition of GSK-3 reduces infarct volume and improves neurobehavioral functions.
Topics: Animals; Behavior, Animal; Blood Glucose; Brain Edema; Calcium-Binding Proteins; Caspase 3; Cerebral Infarction; Cyclooxygenase 2; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glycogen Synthase Kinase 3; Microfilament Proteins; Oxadiazoles; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Thiazoles; Urea | 2008 |
1,3,4-Oxadiazole-3(2H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: synthesis, evaluation, and role of urea moiety.
Topics: Animals; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxadiazoles; Rats; Spectrophotometry, Infrared; Urea | 2008 |
A practical use of ligand efficiency indices out of the fragment-based approach: ligand efficiency-guided lead identification of soluble epoxide hydrolase inhibitors.
Topics: Animals; Databases, Factual; Epoxide Hydrolases; Hep G2 Cells; Humans; Ligands; Molecular Conformation; Oxadiazoles; Protein Binding; Quantitative Structure-Activity Relationship; Solubility; Stereoisomerism; Urea; Young Adult | 2011 |
Acid- and base-catalysis in the mononuclear rearrangement of some (Z)-arylhydrazones of 5-amino-3-benzoyl-1,2,4-oxadiazole in toluene: effect of substituents on the course of reaction.
Topics: Alkalies; Amines; Biological Products; Catalysis; Dioxanes; Hydrazones; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Structure; Oxadiazoles; Piperidines; Structure-Activity Relationship; Temperature; Toluene; Trichloroacetic Acid; Urea; Water | 2011 |
Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Topics: Animals; Chemistry Techniques, Synthetic; Diacylglycerol O-Acyltransferase; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoxazoles; Mice; Oxadiazoles; Solubility; Structure-Activity Relationship; Urea; Water | 2012 |
Identification of new potent GPR119 agonists by combining virtual screening and combinatorial chemistry.
Topics: Cell Line; Combinatorial Chemistry Techniques; Databases, Factual; High-Throughput Screening Assays; Humans; Isoxazoles; Models, Molecular; Oxadiazoles; Receptors, G-Protein-Coupled; Spiro Compounds; Structure-Activity Relationship; Urea | 2012 |
Synthesis and carbonic anhydrase inhibitory properties of tetrazole- and oxadiazole substituted 1,4-dihydropyrimidinone compounds.
Topics: Benzaldehydes; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Enzyme Assays; Humans; Ketones; Oxadiazoles; Pyrimidinones; Sodium Azide; Solutions; Structure-Activity Relationship; Tetrazoles; Urea | 2014 |
Synthesis and broad-spectrum antiproliferative activity of diarylamides and diarylureas possessing 1,3,4-oxadiazole derivatives.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Niacinamide; Oxadiazoles; Phenylurea Compounds; Sorafenib; Structure-Activity Relationship; Urea | 2015 |
A nitric oxide-donor furoxan moiety improves the efficacy of edaravone against early renal dysfunction and injury evoked by ischemia/reperfusion.
Topics: Acetylglucosamine; Acute-Phase Proteins; Animals; Antipyrine; Creatinine; Disease Models, Animal; Edaravone; Free Radical Scavengers; Ischemia; Kidney; Lipid Peroxidation; Lipocalin-2; Lipocalins; Male; Malondialdehyde; Nitric Oxide Donors; Oxadiazoles; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Urea | 2015 |
Design, synthesis, biological evaluation of urea substituted 1,2,5-oxadiazole-3-carboximidamides as novel indoleamine 2,3-dioxygenase-1 (IDO1) inhibitors.
Topics: Animals; Enzyme Inhibitors; HeLa Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Oxadiazoles; Rats; Urea | 2023 |