urea and orotic acid

urea has been researched along with orotic acid in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	98 (77.78)	18.7374
1990's	16 (12.70)	18.2507
2000's	8 (6.35)	29.6817
2010's	3 (2.38)	24.3611
2020's	1 (0.79)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bueno, L	1
Batshaw, M; Brusilow, SW; Valle, DL	1
Decker, K; Nowack, J; Pausch, J; Wilkening, J	1
Gerok, W; Keppler, DO; Pausch, JG	1
Visek, WJ	5
Milner, JA	2
Ha, YH; Milner, JA	1
Böhles, H; Fekl, W; Harms, D; Heid, H; Sitzmann, FC	1
Corbin, JE; Ha, YH; Milner, JA	1
Hatchwell, LC; Milner, JA	2
Milner, JA; Visek, WJ	4
Glasgow, AM	1
Prior, RL	1
Rashid, R	1
Brandt, JT; Fausto, N; Kesner, L	1
Milner, JA; Prior, RL; Visek, WJ	2
Prior, RL; Visek, WJ; Zimber, A	1
Beaudry, MA; Collu, R; Dallairf, L; Ducharme, JR; Leboeuf, G; Letarte, J; Melancon, SB	1
Bordugo, A; Burlina, AB; Dionisi-Vici, C; Ferrari, V; Tuchman, M; Zacchello, F	1
Bödeker, D; Martens, H	1
Brini, CM; Cyr, DM; Egan, SG; Tremblay, GC	1
Hsu, YC; Jeevanandam, M; Ramias, L; Schiller, WR	1
Kukulska, W; Motyl, T; Orzechowski, A; Puchala, R; Siwecka, B	1
Fujiwara, F; Funahashi, S; Hayashi, A; Nakanishi, T; Saiki, K; Shimizu, A	1
Inomata, K; Inoue, Y; Kanemitsu, K; Matsumoto, I; Sano, S; Sasaki, K; Takaoka, O; Yamagata, Y	1
Hjelm, M; Oberholzer, V; Thomas, S; Wilson, J	1
Boedeker, D; Martens, H	1
Daune, G; Gerhart, F; Grauffel, C; Seiler, N	1
Shoemaker, JD; Visek, WJ	2
Azorín, I; Felipo, V; Grisolía, S; Miñana, MD	1
Maswoswe, SM; Tremblay, GC	1
de Silva, LV; Hjelm, M; Oberholzer, VG; Rolles, CJ; Seakins, JW	1
Motyl, T	1
Brusilow, SW; Rajantie, J; Simell, O; Sipilä, I; Valle, DL	1
Kato, T; Mizutani, N; Sano, M	1
Motyl, T; Orzechowski, A; Pierzynowski, S	1
Lin, RC; Snodgrass, PJ	1
Letarte, J; Qureshi, IA; Qureshi, SR; Tuchweber, B; Yousef, I	1
Barej, W; Leontowicz, H; Motyl, T	1
Hjelm, M; Kay, JD; Oberholzer, VG; Seakins, JW	1
Gerok, W; Häussinger, D; Holstege, A; Pausch, J; Rasenack, J	1
Barth, CA; de Vrese, M	1
Morris, JG	1
Goodman, MW; Zieve, L	1
Gushiken, T; Saheki, T; Yoshimura, N	1
Christophe, J; Crokaert, R; Vandermeers-Piret, MC	1
Krooth, RS; Pan, YL; Pinsky, L	1
Gut, J; Santilli, V; Skoda, J; Sorm, F	1
DuBien, LH; Frazier, LE; Getz, GS; Pottenger, LA; Wissler, RW	1
Mandel, HG; Riis, M	1
Milner, JA; Visek, WJ; Wakeling, AE	1
Baker, DH; Easter, RA; Katz, RS	1
Hoogenraad, NJ; Kretchmer, N; Levine, RL	1
Arashima, S; Matsuda, I	1
Prior, RL; Visek, WJ	1
Kamel, MY; Ragaa, RH	1
Buist, NR; Hepburn, CA; Kennaway, NG; Ramberg, DA; Strandholm, JJ	1
Jones, ME	1
Di Girolamo, A; Di Girolamo, M; Gaetani, S; Spadoni, MA	1
Fujisawa, T; Muramatsu, M	1
Heeb, MJ; Sander, EG	1
Hamilton, MG; Pavlovec, A; Petermann, ML	1
Arashima, I	1
Freeman, JM; Levy, HL; Lindenbaum, JE; Sunshine, P	1
Mackenzie, S; MacLeod, P; Scriver, CR	1
Anakura, M; Arashima, S; Matsuda, I; Nambu, H; Takekoshi, Y	1
Hadjiolov, AA	1
Molnár, J	1
Shaposhinkov, VN; Shvachkin, IuP; Vitol, MIa	1
Cook, EA; Hastings, JR; Kirby, KS; Parish, JH	1
Bain, JA; Huguley, CM; Vogler, WR	1
Ishihara, H; Wang, SY	1
Berlinguet, L; Charbonneau, R; Roberge, A	1
Tremblay, GC; Wendler, PA	1
Blanding, JH; Tremblay, GC	1
Cerra, FB; Goodman, MW; Konstantinides, FN; Zieve, L	1
Nagasaki, T	1
Steele, RD	1
Baker, DH; Czarnecki, GL	1
Fico, ME; Milner, JA; Motyl, T	1
Hevia, P; Kari, FW; Ulman, EA; Visek, WJ	1
Fico, ME; Hassan, AS; Milner, JA	1
Blanding, JH; Tremblay, GC; Wendler, PA	1
Letarte, J; Ouellet, R; Qureshi, IA	1
Kubota, K; Murakami, T; Yamashita, F; Yoshida, I; Yoshino, M	1
Auray-Blais, C; Giguère, R; Lemieux, B	1
Altman, RP; Glasgow, AM; Schulman, JD; Stolar, CJ	1
Laberge, C; Lelièvre, M; Letarte, J; Ouellet, R; Qureshi, IA	1
Rajantie, J	1
Gargallo, J; Zimmerman, D	1
Carter, M; Donnel, GN; Koch, R; McLaren, J; Ng, WG; Oizumi, J; Shaw, KN	1
Lambert, M; Qureshi, IA; Rajalakshmi, S; Rao, PM; Sarma, DS; Vasudevan, S	1
Hartman, WJ; Prior, RL; Torre, PM	1
Klahr, S; Reyes, AA	1
Kirchgessner, M; Kreuzer, M; Vertesy, E	1
Donati, MA; Filippi, L; Resti, M; Zammarchi, E	1
Allen, JC; Bonham, JR; Downing, M; Duley, JA; Fairbanks, LD; Fensom, A; Guthrie, P; Land, JM; O'Neill, D; Rittey, C; Sharrard, M; Tanner, MS	1
Lukkarinen, M; Mattila, K; Näntö-Salonen, K; Pulkki, K; Simell, O	1
Cederbaum, SD; Steiner, RD	1
Farriol, M; Fernandez-Bustos, MA; Pita, AM; Riudor, E; Soler, J; Virgili, N; Wakabayashi, Y	1
Cremades, A; Monserrat, F; Peñafiel, R; Ruzafa, C	1
ISHIDATE, M; MIURA, Y; NOGUCHI, T; TAKEYAMA, S	1
AMSTEY, M; BROWN, O; MCCARTY, KS; WOODSON, B	1
COHEN, PP; KIM, S	1
HUFF, JW; LIEBERT, KV; SPICER, DS; WRIGHT, LD	1
Kim, SW; McPherson, RL; Wu, G	1
Erkkola, R; Huoponen, K; Näntö-Salonen, K; Niinikoski, H; Simell, O; Tanner, L	1
Adachi, M; Kanazawa, M; Kobayashi, K; Kubota, M; Kurokawa, K; Murakami, T; Murayama, K; Nagasaka, H; Ogawa, A; Ogawa, E; Takatani, T; Takayanagi, M; Yamamoto, S; Yorifuji, T	1
Bartkowiak, G	1
MITCHELL, HK; NYC, JF	1
Drake, MA; Frankowski, KM; Miracle, RE	1
Azevedo, FA; Briso, ALF; Cintra, LTA; Frascino, SMB; Gallinari, MO; Gonçalves, RS; Rahal, V; Santos, PHD	1
Hall, PL; Wilcox, WR; Wittenauer, AL	1

Reviews

8 review(s) available for urea and orotic acid

Article	Year
Ammonia metabolism, urea cycle capacity and their biochemical assessment. Nutrition reviews, 1979, Volume: 37, Issue:9 Topics: Amino Acids; Ammonia; Animals; Arginine; Brain; Citric Acid Cycle; Humans; Nutritional Requirements; Ornithine; Orotic Acid; Polyamines; Quaternary Ammonium Compounds; Urea	1979
Orotic acid, arginine, and hepatotoxicity. Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2 Topics: Adult; Alcoholism; Ammonia; Animals; Arginine; Dietary Fats; Dietary Proteins; Ethanol; Fasting; Ferrets; Food; Humans; Liver; Liver Diseases, Alcoholic; Liver Regeneration; Male; Models, Biological; Orotic Acid; Rats; Reye Syndrome; Urea	1986
A review: biological and clinical aspects of pyrimidine metabolism. Pediatric research, 1974, Volume: 8, Issue:7 Topics: Ammonia; Animals; Cats; Cell Transformation, Neoplastic; Cytidine; Glucose; Humans; Isoproterenol; Lectins; Lipid Metabolism; Liver Regeneration; Lymphocyte Activation; Mice; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidine Nucleotides; Rats; Salivary Glands; Thymine; Uracil Nucleotides; Urea; Uridine; Uridine Diphosphate Sugars	1974
Regulation of pyrimidine and arginine biosynthesis in mammals. Advances in enzyme regulation, 1970, Volume: 9 Topics: Amidohydrolases; Animals; Arginine; Aspartic Acid; Bacillus; Basidiomycota; Carbamates; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Enzyme Induction; Enzyme Repression; Escherichia coli; Feedback; Humans; Ligases; Lyases; Mice; Neurospora; Nucleotides; Ornithine Carbamoyltransferase; Orotic Acid; Oxidoreductases; Pentosyltransferases; Phosphotransferases; Pseudomonas; Pyrimidines; Saccharomyces; Transferases; Uracil; Urea	1970
Ammonia: its effects on biological systems, metabolic hormones, and reproduction. Journal of dairy science, 1984, Volume: 67, Issue:3 Topics: Ammonia; Animals; Cats; Cattle; Chickens; Cricetinae; Dietary Proteins; Dogs; Estrus; Female; Guinea Pigs; Hormones; Horses; Humans; Inactivation, Metabolic; Insulin; Liver; Luteinizing Hormone; Mice; Orotic Acid; Pregnancy; Progesterone; Rabbits; Rats; Reproduction; Sheep; Species Specificity; Urea	1984
An update of concepts of essential amino acids. Annual review of nutrition, 1984, Volume: 4 Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Ammonia; Animals; Arginine; Atrophy; Child; Choroid; Dietary Proteins; Female; Glucose Tolerance Test; Growth; Histidine; Humans; Insulin; Kidney Failure, Chronic; Male; Middle Aged; Nitrogen; Nutritional Requirements; Orotic Acid; Pregnancy; Retinal Diseases; Reye Syndrome; Urea; Uveal Diseases; Wounds and Injuries	1984
Orotic aciduria and species specificity. Nutrition reviews, 1984, Volume: 42, Issue:8 Topics: Ammonia; Animals; Arginine; Cats; Cattle; Dogs; Humans; Lipids; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Rats; Species Specificity; Swine; Urea	1984
Laboratory evaluation of urea cycle disorders. The Journal of pediatrics, 2001, Volume: 138, Issue:1 Suppl Topics: Algorithms; Amino Acid Metabolism, Inborn Errors; Citrulline; DNA Mutational Analysis; Humans; Hyperammonemia; Orotic Acid; Urea	2001

Trials

2 trial(s) available for urea and orotic acid

Article	Year
Effects of arginine treatment on nutrition, growth and urea cycle function in seven Japanese boys with late-onset ornithine transcarbamylase deficiency. European journal of pediatrics, 2006, Volume: 165, Issue:9 Topics: Age of Onset; Amino Acids; Ammonia; Analysis of Variance; Arginine; Biomarkers; Blood Proteins; Body Height; Body Weight; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Diet, Protein-Restricted; Growth; Growth Hormone; Humans; Hyperammonemia; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Japan; Male; Nutritional Physiological Phenomena; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Thyrotropin; Time Factors; Treatment Outcome; Triglycerides; Urea	2006
Neurosensory analysis of tooth sensitivity during at-home dental bleaching: a randomized clinical trial. Journal of applied oral science : revista FOB, 2018, Volume: 26 Topics: Adolescent; Adult; Analysis of Variance; Carbamide Peroxide; Dentin Sensitivity; Female; Humans; Male; Orotic Acid; Pain Measurement; Pain Threshold; Peroxides; Severity of Illness Index; Time Factors; Tooth Bleaching; Tooth Bleaching Agents; Treatment Outcome; Urea; Visual Analog Scale; Young Adult	2018

Article

Year

Effects of arginine treatment on nutrition, growth and urea cycle function in seven Japanese boys with late-onset ornithine transcarbamylase deficiency.

European journal of pediatrics, 2006, Volume: 165, Issue:9

Topics: Age of Onset; Amino Acids; Ammonia; Analysis of Variance; Arginine; Biomarkers; Blood Proteins; Body Height; Body Weight; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Diet, Protein-Restricted; Growth; Growth Hormone; Humans; Hyperammonemia; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Japan; Male; Nutritional Physiological Phenomena; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Thyrotropin; Time Factors; Treatment Outcome; Triglycerides; Urea

2006

Neurosensory analysis of tooth sensitivity during at-home dental bleaching: a randomized clinical trial.

Journal of applied oral science : revista FOB, 2018, Volume: 26

Topics: Adolescent; Adult; Analysis of Variance; Carbamide Peroxide; Dentin Sensitivity; Female; Humans; Male; Orotic Acid; Pain Measurement; Pain Threshold; Peroxides; Severity of Illness Index; Time Factors; Tooth Bleaching; Tooth Bleaching Agents; Treatment Outcome; Urea; Visual Analog Scale; Young Adult

2018

Other Studies

116 other study(ies) available for urea and orotic acid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Orotic acid and non-protein nitrogen overload in sheep. Annales de recherches veterinaires. Annals of veterinary research, 1979, Volume: 10, Issue:1 Topics: Acetates; Ammonia; Animals; Eating; Female; Gastrointestinal Motility; Hydrogen-Ion Concentration; Nitrogen; Orotic Acid; Rumen; Sheep; Urea	1979
New pathways of nitrogen excretion in inborn errors of urea synthesis. Lancet (London, England), 1979, Sep-01, Volume: 2, Issue:8140 Topics: Arginine; Argininosuccinate Synthase; Argininosuccinic Aciduria; Citrulline; Dietary Proteins; Hippurates; Humans; Infant; Metabolism, Inborn Errors; Nitrogen; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phenylacetates; Urea	1979
Control of pyrimidine biosynthesis in the perfused liver. Feedback inhibition of glutamine-dependent carbamoyl phosphate synthetase. European journal of biochemistry, 1975, May-06, Volume: 53, Issue:2 Topics: Adenosine Triphosphate; Animals; Bicarbonates; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Female; Galactosamine; Kinetics; Liver; Orotic Acid; Oxaloacetates; Perfusion; Phosphotransferases; Pyrimidines; Rats; Time Factors; Uracil Nucleotides; Urea; Uridine Diphosphate Glucose	1975
Increased de novo pyrimidine nucleotide synthesis in liver induced by ammonium ions in amounts surpassing the urea cycle capacity. European journal of biochemistry, 1977, Jun-01, Volume: 76, Issue:1 Topics: Animals; Azauridine; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Hepatocellular; Cytosine Nucleotides; Dose-Response Relationship, Drug; Female; Liver; Liver Neoplasms; Mitochondria, Liver; Models, Biological; Ornithine; Orotic Acid; Pyrimidine Nucleotides; Quaternary Ammonium Compounds; Rats; Uracil Nucleotides; Urea; Uridine Diphosphate Glucose	1977
Mechanism for fatty liver induction in rats fed arginine deficient diets. The Journal of nutrition, 1979, Volume: 109, Issue:4 Topics: Adenine; Animals; Arginine; Body Weight; Cholesterol; Citrates; Fatty Liver; Female; Guanine; Lipid Metabolism; Male; Orotic Acid; Phospholipids; Rats; Triglycerides; Urea	1979
Urea cycle operation in the arginine deficient rat. Biochemical medicine, 1979, Volume: 22, Issue:2 Topics: Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Citrulline; Liver; Male; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Urea	1979
Protein load in argininosuccinic aciduria: thoughts on its biochemical implications. Zeitschrift fur Ernahrungswissenschaft, 1978, Volume: 17, Issue:2 Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Argininosuccinic Acid; Argininosuccinic Aciduria; Dietary Proteins; Female; Humans; Milk Proteins; Orotic Acid; Urea	1978
Arginine requirements in immature dogs. The Journal of nutrition, 1978, Volume: 108, Issue:2 Topics: Amino Acids; Ammonia; Animals; Arginine; Citrates; Dogs; Hyperglycemia; Nutritional Requirements; Orotic Acid; Sialorrhea; Tremor; Urea	1978
Amino acid induced orotic aciduria. The Journal of nutrition, 1978, Volume: 108, Issue:4 Topics: Amino Acids; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Fasting; Male; Ornithine; Orotic Acid; Quaternary Ammonium Compounds; Rats; Urea; Urease	1978
Orotic aciduria in the female rat and its relation to dietary arginine. The Journal of nutrition, 1978, Volume: 108, Issue:8 Topics: Aging; Ammonia; Animals; Arginine; Birth Weight; Body Weight; Citrates; Female; Litter Size; Orotic Acid; Pregnancy; Pregnancy Complications; Rats; Species Specificity; Urea	1978
Factors affecting amino acid induced orotic aciduria in rats. The Journal of nutrition, 1978, Volume: 108, Issue:12 Topics: Ammonia; Animals; Dietary Proteins; Digestion; Glycine; Male; Nitrogen; Orotic Acid; Rats; Starvation; Urea	1978
Potential hazard of therapy for Reye's syndrome with urea cycle intermediates. Pediatrics, 1977, Volume: 60, Issue:4 Topics: Ammonia; Humans; Ornithine; Orotic Acid; Reye Syndrome; Urea	1977
Effects of dietary soy or urea nitrogen and feeding frequency on nitrogen metabolism, glucose metabolism and urinary metabolite excretion in sheep. Journal of animal science, 1976, Volume: 42, Issue:1 Topics: Animal Feed; Animals; Blood Glucose; Citrates; Creatinine; Glycine max; Male; Nitrogen; Orotic Acid; Sheep; Time Factors; Urea	1976
Acid-soluble purine and pyrimidine derivatives in cow's milk produced on normal feed and almost protein-free-feed with urea as the main nitrogen source. Die Nahrung, 1976, Volume: 20, Issue:10 Topics: Animal Feed; Animals; Cattle; Cytosine Nucleotides; Dietary Proteins; Female; Lactation; Milk; Nucleotides; Orotic Acid; Pregnancy; Protein Deficiency; Purines; Pyrimidines; Urea; Uric Acid	1976
Possible interactions between the urea cycle and synthesis of pyrimidines and polyamines in regenerating liver. Cancer research, 1975, Volume: 35, Issue:2 Topics: Adrenalectomy; Ammonia; Animals; Bicarbonates; Carbon Radioisotopes; Carboxy-Lyases; Hepatectomy; Liver; Liver Regeneration; Male; Ornithine; Orotic Acid; Polyamines; Pyrimidines; Rats; Urea; Urease	1975
Urea, citrate and orotate excretion in growing rats fed amino acid-deficient diets. The Journal of nutrition, 1975, Volume: 105, Issue:2 Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Arginine; Citrates; Deficiency Diseases; Lysine; Male; Orotic Acid; Rats; Urea	1975
Citric, orotic, and other organic acids in rats injected with active or inactive urease. The American journal of physiology, 1975, Volume: 228, Issue:3 Topics: Acetates; Ammonia; Animals; Arginine; Blood Glucose; Citrates; Formates; Ketoglutaric Acids; Lactates; Malates; Male; Orotic Acid; Pyruvates; Rats; Succinates; Time Factors; Urea; Urease	1975
Urinary metabolites characteristic of urea-cycle amino acid deficiency. Metabolism: clinical and experimental, 1975, Volume: 24, Issue:5 Topics: Amino Acids; Amino Acids, Essential; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Biotransformation; Body Weight; Carbamyl Phosphate; Citrates; Citrulline; Deficiency Diseases; Diet; Male; Nitrogen; Ornithine; Orotic Acid; Pyrimidines; Rats; Urea	1975
Arginine deficiency and orotic aciduria in mammals. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:2 Topics: Animals; Arginine; Cricetinae; Diet; Dogs; Guinea Pigs; Mice; Orotic Acid; Rabbits; Rats; Species Specificity; Urea	1975
[Chronic hyperammonemia with orotic aciduria: evidence of pyrimidine pathway stimulation (author's transl)]. Diabete & metabolisme, 1975, Volume: 1 Topics: Alanine; Amino Acids; Ammonia; Child, Preschool; Dietary Proteins; Erythrocytes; Growth Disorders; Humans; Intellectual Disability; Leukocytes; Ornithine; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Seizures; Syndrome; Urea	1975
Allopurinol challenge test in children. Journal of inherited metabolic disease, 1992, Volume: 15, Issue:5 Topics: Adolescent; Aging; Allopurinol; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea; Uridine	1992
Nitrogen-stimulated orotic acid synthesis and nucleotide imbalance. Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl Topics: Ammonia; Animals; Carbamyl Phosphate; Cattle; Humans; Liver Neoplasms; Milk; Orotic Acid; Pyrimidines; Rats; Triglycerides; Urea	1992
Elevated urinary excretion of orotic acid in sheep caused by intraruminal infusion of sodium propionate. Comparative biochemistry and physiology. B, Comparative biochemistry, 1992, Volume: 102, Issue:2 Topics: Animals; Infusions, Parenteral; Nitrogen; Orotic Acid; Propionates; Rumen; Sheep; Sodium Chloride; Urea	1992
On the mechanism of inhibition of gluconeogenesis and ureagenesis by sodium benzoate. Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3 Topics: Acetyl Coenzyme A; Adenine Nucleotides; Animals; Aspartic Acid; Benzoates; Benzoic Acid; Bicarbonates; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Enzyme Activation; Gluconeogenesis; Glutamates; Glutamic Acid; Kinetics; Liver; Male; Mitochondria, Liver; Orotic Acid; Pyruvate Carboxylase; Rats; Sodium; Sodium Bicarbonate; Urea	1991
Mild orotic aciduria and uricosuria in severe trauma victims. The American journal of clinical nutrition, 1991, Volume: 53, Issue:5 Topics: Adult; Amino Acids; Creatinine; Enteral Nutrition; Female; Fluid Therapy; Glucose; Humans; Male; Middle Aged; Multiple Trauma; Nitrogen; Orotic Acid; Parenteral Nutrition; Purines; Pyrimidines; Trauma Severity Indices; Urea; Uric Acid	1991
Urinary excretion of purines in sheep with experimental orotic aciduria. Zentralblatt fur Veterinarmedizin. Reihe A, 1991, Volume: 38, Issue:3 Topics: Allantoin; Animals; Female; Hypoxanthine; Hypoxanthines; Orotic Acid; Purines; Sheep; Sheep Diseases; Urea; Uric Acid	1991
Quantitative analysis of urinary pyroglutamic acid in patients with hyperammonemia. Clinica chimica acta; international journal of clinical chemistry, 1991, Mar-29, Volume: 197, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Amino Acid Metabolism, Inborn Errors; Ammonia; Carbamoyl-Phosphate Synthase (Ammonia); Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Infant; Infant, Newborn; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Pyrrolidonecarboxylic Acid; Urea	1991
Prebiotic synthesis of orotic acid parallel to the biosynthetic pathway. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1990, Volume: 20, Issue:5 Topics: Aspartic Acid; Kinetics; Molecular Structure; Orotic Acid; Urea	1990
The urea cycle in the Rett syndrome. Brain & development, 1990, Volume: 12, Issue:1 Topics: Adult; Ammonia; Child; Child, Preschool; Female; Humans; Middle Aged; Orotic Acid; Rett Syndrome; Urea	1990
Urinary orotic acid excretion in sheep: effects of nitrogen, glucose and arginine. The Journal of nutrition, 1990, Volume: 120, Issue:9 Topics: Abomasum; Ammonia; Animals; Arginine; Aspartate Aminotransferases; Bilirubin; Energy Intake; Feces; Glucose; Male; Nitrogen; Orotic Acid; Rumen; Sheep; Urea	1990
Ornithine aminotransferase activity, liver ornithine concentration and acute ammonia intoxication. Life sciences, 1989, Volume: 45, Issue:11 Topics: Acetates; Administration, Oral; Ammonia; Animals; Arginine; Creatinine; Eflornithine; Female; Injections, Intraperitoneal; Liver; Mice; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Transaminases; Urea	1989
Orotic acid overproduction in experimental cirrhosis of rats. Experimental and molecular pathology, 1989, Volume: 50, Issue:3 Topics: Ammonia; Animals; Carbon Tetrachloride; Liver; Liver Cirrhosis, Experimental; Male; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1989
A simple animal model of hyperammonemia. Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:3 Topics: Acetates; Ammonia; Animals; Citrulline; Disease Models, Animal; Glutamate Dehydrogenase; Liver; Male; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1989
Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats. The Journal of nutrition, 1989, Volume: 119, Issue:2 Topics: Ammonium Chloride; Animals; Benzoates; Choline Deficiency; Diet; Fatty Liver; Gluconeogenesis; Hippurates; Inositol; Liver; Obesity; Ornithine; Orotic Acid; Pyrimidines; Rats; Rats, Inbred Strains; Rats, Zucker; Urea	1989
Evidence of inherited urea cycle defect in a case of fatal valproate toxicity. British medical journal (Clinical research ed.), 1986, Jan-04, Volume: 292, Issue:6512 Topics: Adult; Ammonia; Child; Child, Preschool; Female; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Orotic Acid; Urea; Valproic Acid	1986
The urinary excretion of orotic acid and urea in dairy cows in early lactation. Zentralblatt fur Veterinarmedizin. Reihe A, 1986, Volume: 33, Issue:3 Topics: Animals; Cattle; Female; Lactation; Orotic Acid; Pregnancy; Urea	1986
Waste nitrogen excretion via amino acid acylation: benzoate and phenylacetate in lysinuric protein intolerance. Pediatric research, 1986, Volume: 20, Issue:11 Topics: Acylation; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Benzoates; Benzoic Acid; Child; Child, Preschool; Creatinine; Glutamine; Hippurates; Humans; Lysine; Nitrogen; Orotic Acid; Phenylacetates; Urea	1986
Inhibitory effect of intravenous lysine infusion on urea cycle metabolism. European journal of pediatrics, 1987, Volume: 146, Issue:1 Topics: Adolescent; Amino Acids; Ammonia; Child; Citric Acid Cycle; Citrulline; Depression, Chemical; Female; Humans; Infusions, Intravenous; Lysine; Male; Orotic Acid; Putrescine; Urea	1987
The relationship between urea and pyrimidine de novo synthesis in ruminant liver. Quarterly journal of experimental physiology (Cambridge, England), 1988, Volume: 73, Issue:1 Topics: Amino Acids; Ammonia; Animals; Biological Transport; Female; Liver; Orotic Acid; Pyrimidines; Sheep; Urea	1988
Differing effects of arginine deficiency on the urea cycle enzymes of rat liver, cultured hepatocytes and hepatoma cells. The Journal of nutrition, 1987, Volume: 117, Issue:11 Topics: Ammonium Chloride; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Urea; Uridine; Valine	1987
The role of hepatic ornithine transcarbamylase deficiency in the orotic aciduria of pregnant mice. European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 22, Issue:3 Topics: Animals; Creatinine; Fatty Liver; Female; Genotype; Liver; Mice; Mice, Mutant Strains; Mitochondria, Liver; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Pregnancy; Pregnancy, Animal; Time Factors; Urea	1986
The orotic acid concentration in the blood, milk, and urine of dairy cows fed with urea supplemented diet. Archiv fur Tierernahrung, 1986, Volume: 36, Issue:6 Topics: Animal Feed; Animals; Cattle; Female; Food, Fortified; Lactation; Milk; Orotic Acid; Pregnancy; Time Factors; Urea	1986
Effect of partial ornithine carbamoyltransferase deficiency on urea synthesis and related biochemical events. Clinical science (London, England : 1979), 1987, Volume: 72, Issue:2 Topics: Alanine; Ammonia; Child; Female; Humans; Kinetics; Male; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea	1987
The glutamine analog acivicin as antipyrimidine. Studies on the interrelationship between pyrimidine and urea synthesis in liver. Advances in enzyme regulation, 1985, Volume: 24 Topics: Animals; Antibiotics, Antineoplastic; Carbamyl Phosphate; Cytosol; Female; Isoxazoles; Liver; Mitochondria, Liver; Orotic Acid; Oxazoles; Pyrimidines; Rats; Rats, Inbred Strains; Urea	1985
Arginine and disease states. The Journal of nutrition, 1985, Volume: 115, Issue:4 Topics: Ammonia; Animals; Arginine; Blood Glucose; Humans; Insulin; Lipid Metabolism; Liver Diseases; Male; Nutritional Requirements; Orotic Acid; Retinal Degeneration; Reye Syndrome; Spermatogenesis; Urea	1985
Influence of lysine on urea cycle activity and orotate formation in the isolated perfused rat liver. Biological chemistry Hoppe-Seyler, 1985, Volume: 366, Issue:5 Topics: Ammonia; Animals; In Vitro Techniques; Kinetics; Liver; Lysine; Male; Ornithine; Orotic Acid; Perfusion; Rats; Rats, Inbred Strains; Urea	1985
Metabolic aberrations associated with arginine deficiency. The Journal of nutrition, 1985, Volume: 115, Issue:4 Topics: Ammonia; Animals; Arginine; Citrates; Citric Acid; Diet; Humans; Lipid Metabolism; Liver; Orotic Acid; Purines; Pyrimidines; Urea	1985
Nutritional and metabolic responses to arginine deficiency in carnivores. The Journal of nutrition, 1985, Volume: 115, Issue:4 Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Carnivora; Cats; Citrulline; Dogs; Glutamine; Intestinal Mucosa; Kidney; Liver; Muscles; Nutritional Requirements; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Rats; Species Specificity; Urea	1985
Carbamoyl-phosphate synthetase I activity and ureagenesis in regenerating liver of the normal rat. The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1 Topics: Ammonia; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Ligases; Liver; Liver Regeneration; Male; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1985
Transient hyperammonemia during aging in ornithine transcarbamylase-deficient, sparse-fur mice. Biochemistry international, 1985, Volume: 11, Issue:5 Topics: Aging; Ammonia; Animals; Body Weight; Disease Models, Animal; Hair; Liver; Mice; Mice, Mutant Strains; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea	1985
[Catabolism of uracil in Torulopsis utilis]. Archives internationales de physiologie et de biochimie, 1964, Volume: 72, Issue:2 Topics: Barbiturates; Chromatography; In Vitro Techniques; Mitosporic Fungi; Orotic Acid; Propionates; Uracil; Urea	1964
Studies of the orotidine 5'-monophosphate decarboxylase activity of crude extracts of human cells. Biochemical genetics, 1973, Volume: 8, Issue:2 Topics: Barbiturates; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromosome Aberrations; Chromosome Disorders; Diploidy; Fibroblasts; Humans; Hydrogen-Ion Concentration; Kinetics; Mathematics; Mutation; Neurospora crassa; Orotic Acid; Phosphates; Proteins; Urea	1973
Dihydro-5-azaorotic acid, the first specific inhibitor of dihydro-orotate dehydrogenase. Biochimica et biophysica acta, 1968, Feb-26, Volume: 155, Issue:2 Topics: Acids; Animals; Carbon Isotopes; Carboxy-Lyases; Diphosphates; Glucosyltransferases; In Vitro Techniques; Liver; Mice; NAD; Nucleosides; Nucleotides; Orotic Acid; Oxidoreductases; Succinates; Triazines; Uracil; Urea	1968
Carbohydrate composition of lipoprotein apoproteins isolated from rat plasma and from the livers of rats fed orotic acid. Biochemical and biophysical research communications, 1973, Sep-18, Volume: 54, Issue:2 Topics: Animals; Apoproteins; Chromatography, Gas; Chromatography, Gel; Electrophoresis, Disc; Galactose; Glucosamine; Glucose; Lipoproteins, VLDL; Liposomes; Liver; Male; Mannose; Neuraminic Acids; Orotic Acid; Rats; Ultracentrifugation; Urea	1973
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus. Biochemical pharmacology, 1970, Volume: 19, Issue:6 Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea	1970
Effect of arginine deficiency on growth and intermediary metabolism in rats. The Journal of nutrition, 1974, Volume: 104, Issue:12 Topics: Amino Acids; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Citrates; Creatinine; Deficiency Diseases; Diet; Male; Nitrogen; Orotic Acid; Rats; Time Factors; Urea; Urine	1974
Arginine: a dispensable amino acid for postpubertal growth and pregnancy of swine. Journal of animal science, 1974, Volume: 39, Issue:6 Topics: Amino Acids; Animal Feed; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Citrates; Feces; Female; Hemoglobins; Nitrogen; Nutritional Requirements; Orotic Acid; Pregnancy; Pregnancy, Animal; Swine; Urea	1974
Orotate, citrate, and urea excretion in rats fed various levels of arginine. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 147, Issue:3 Topics: Ammonia; Ammonium Chloride; Animals; Arginine; Citrates; Diet; Male; Orotic Acid; Rats; Sodium Chloride; Urea	1974
Orotic aciduria and arginine deficiency. Nature, 1973, Sep-28, Volume: 245, Issue:5422 Topics: Ammonia; Animals; Arginine; Deficiency Diseases; Orotic Acid; Rats; Urea	1973
A case of carbamyl phosphate synthetase deficiency. The Tohoku journal of experimental medicine, 1972, Volume: 107, Issue:2 Topics: Amino Acids; Carbamates; DNA; Female; Glucose Tolerance Test; Humans; Infant; Liver; Metabolism, Inborn Errors; Orotic Acid; Phosphotransferases; RNA; Urea	1972
Effects of urea in rats deprived of arginine. The Journal of nutrition, 1973, Volume: 103, Issue:8 Topics: Aconitic Acid; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Carbohydrate Metabolism; Carboxylic Acids; Citrates; Citric Acid Cycle; Deficiency Diseases; Isocitrates; Ketoglutaric Acids; Lactates; Liver; Male; Nitrogen; Organ Size; Orotic Acid; Pyrimidine Nucleotides; Rats; Stereoisomerism; Succinates; Urea	1973
Constitutive synthesis of urease in Aerobacter aerogenese PRL-R3. The effect of different nitrogenous compounds on its inhibition and formation. Acta biologica et medica Germanica, 1973, Volume: 30, Issue:4 Topics: Allantoin; Alloxan; Ammonium Sulfate; Barbiturates; Cell Membrane Permeability; Enterobacter; Enzyme Induction; Enzyme Repression; Orotic Acid; Uracil; Urea; Urease; Xanthines	1973
Citrullinemia: investigation and treatment over a four-year period. The Journal of pediatrics, 1974, Volume: 85, Issue:2 Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginine; Child, Preschool; Citrulline; Dietary Proteins; Dipeptides; Female; Fibroblasts; Follow-Up Studies; Guanidines; Humans; Infant; Infant, Newborn; Orotic Acid; Peptide Synthases; Urea; Uric Acid	1974
Characterization of ribonucleic acid with template activity in rat liver cytoplasm. European journal of biochemistry, 1967, Volume: 1, Issue:2 Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Edetic Acid; Liver; Neomycin; Orotic Acid; Rats; RNA; Templates, Genetic; Urea; Valine	1967
Studies on the sedimentation properties of nuclear, nuclelar and extranucleolar nuclear RNA. Biochimica et biophysica acta, 1968, Nov-20, Volume: 169, Issue:1 Topics: Amylases; Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Deoxyribonucleases; Edetic Acid; Hydrogen-Ion Concentration; Liver; Molecular Weight; Orotic Acid; Peptide Hydrolases; Rats; RNA; Sulfones; Thiophenes; Tritium; Urea	1968
Purification and properties of dihydroorotase from Escherichia coli B. Biochimica et biophysica acta, 1971, Feb-10, Volume: 227, Issue:2 Topics: Alkylating Agents; Amidohydrolases; Amino Acids; Arsenic; Buffers; Carbamates; Chromatography, Gel; Cobalt; Edetic Acid; Electrophoresis; Enzyme Activation; Escherichia coli; Glutamates; Glycine; Iodoacetates; Mercury; Molecular Weight; Nitrobenzenes; Organometallic Compounds; Orotic Acid; Phenylacetates; Phosphates; Serine; Silver Nitrate; Succinates; Sulfhydryl Compounds; Sulfonic Acids; Urea; Zinc	1971
Molecular weight, buoyant density, and composition of active subunits of rat liver ribosomes. Biochemistry, 1971, Aug-31, Volume: 10, Issue:18 Topics: Animals; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Dialysis; Dithiothreitol; Edetic Acid; Formaldehyde; Liver; Macromolecular Substances; Magnesium; Male; Molecular Weight; Orotic Acid; Phosphates; Potassium; Potassium Chloride; Proteins; Rats; Ribosomes; RNA; RNA, Ribosomal; Time Factors; Tritium; Urea	1971
[Hyperammonemia--congenital abnormality of the urea cycle]. Saishin igaku. Modern medicine, 1972, Volume: 27, Issue:4 Topics: Amino Acids; Ammonia; Animals; Arginase; Carbamates; DNA; Female; Humans; Infant; Kinetics; Ligases; Liver; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase; Orotic Acid; Phosphotransferases; Rats; RNA; Urea	1972
Hyperammonemia due to a defect in hepatic ornithine transcarbamylase. Pediatrics, 1972, Volume: 50, Issue:1 Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Central Nervous System Diseases; Child; Child Behavior Disorders; Citrates; Coma; Diet Therapy; Dietary Proteins; Female; Gastrointestinal Diseases; Guanidines; Humans; Liver; Male; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Succinates; Urea	1972
Partial ornithine carbamyl transferase deficiency: an inborn error of the urea cycle presenting as orotic aciduria in a male infant. Canadian Medical Association journal, 1972, Sep-09, Volume: 107, Issue:5 Topics: Ammonia; Chromatography, Gas; Coma; Humans; Infant; Infusions, Parenteral; Liver; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase; Orotic Acid; Spectrophotometry, Ultraviolet; Urea; Vomiting	1972
Hyperammonemia due to a mutant enzyme of ornithine transcarbamylase. Pediatrics, 1971, Volume: 48, Issue:4 Topics: Amino Acids; Ammonia; Animals; Autopsy; Clinical Enzyme Tests; Culture Techniques; Female; Humans; Infant; Liver; Metabolism, Inborn Errors; Mutation; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Phosphotransferases; Rats; Threonine; Urea	1971
Studies on the turnover and messenger activity of rat-liver ribonucleic acids. Biochimica et biophysica acta, 1966, Jun-22, Volume: 119, Issue:3 Topics: Animals; Escherichia coli; Hot Temperature; In Vitro Techniques; Liver; Orotic Acid; Rats; Ribosomes; RNA, Messenger; Ultracentrifugation; Urea	1966
Protein composition of the messenger RNA-containing ribonucleoprotein of the nucleus. Acta biochimica et biophysica; Academiae Scientiarum Hungaricae, 1969, Volume: 4, Issue:1 Topics: Animals; Carbon Isotopes; Cattle; Cell Nucleus; Centrifugation, Density Gradient; Electrophoresis, Disc; Isotope Labeling; Liver; Nucleoproteins; Orotic Acid; Pancreas; Proteins; Rats; Ribonucleases; Ribosomes; RNA, Messenger; Time Factors; Urea	1969
[New route of catabolism of orotic acid in microorganisms]. Doklady Akademii nauk SSSR, 1967, Jun-11, Volume: 174, Issue:5 Topics: Barbiturates; Carbon Isotopes; Mycobacterium; Orotic Acid; Polarography; Uracil; Urea	1967
Sedimentation of rapidly labelled RNA from rat liver in different gradients. Biochimica et biophysica acta, 1968, Feb-26, Volume: 155, Issue:2 Topics: Animals; Centrifugation, Density Gradient; Chloral Hydrate; Chlorine; Liver; Orotic Acid; Radioisotopes; Rats; RNA; Sucrose; Sulfones; Tritium; Urea	1968
In vivo effect of hydroxyurea on orotic acid synthesis. Cancer research, 1966, Volume: 26, Issue:9 Topics: Adult; Aged; Antimetabolites; DNA; Humans; Leukemia; Melanoma; Middle Aged; Nucleosides; Orotic Acid; RNA; Urea	1966
Photochemistry of 5-bromouracil in aqueous solution. Biochemistry, 1966, Volume: 5, Issue:7 Topics: Allantoin; Ammonia; Barbiturates; Chemical Phenomena; Chemistry; Orotic Acid; Oxalates; Radiation Effects; Solutions; Ultraviolet Rays; Uracil; Urea	1966
Variation of the enzymes of the urea cycle and aspartate transcarbamylase in liver of pregnant rats. Canadian journal of biochemistry, 1967, Volume: 45, Issue:9 Topics: Animals; Arginase; Female; Ligases; Liver; Lyases; Male; Ornithine Carbamoyltransferase; Orotic Acid; Phosphotransferases; Pregnancy; Rats; Sex Factors; Transferases; Urea	1967
Quantitative isolation of radiolabeled metabolites without chromatography: measurements of the biosynthesis of purines, pyrimidines, and urea in isolated hepatocytes. Analytical biochemistry, 1980, Nov-01, Volume: 108, Issue:2 Topics: Adenine Nucleotides; Animals; Bicarbonates; Carbon Radioisotopes; Cells, Cultured; Crystallization; Isotope Labeling; Liver; Male; Orotic Acid; Rats; Sodium Bicarbonate; Uracil Nucleotides; Urea	1980
Ammonia detoxification in the fatty liver. Biochemical and biophysical research communications, 1982, Aug-31, Volume: 107, Issue:4 Topics: Acetates; Ammonium Chloride; Animals; Bicarbonates; Fatty Liver; In Vitro Techniques; Liver; Male; Orotic Acid; Rats; Rats, Inbred Strains; Sodium Bicarbonate; Urea	1982
Mechanism of arginine protection against ammonia intoxication in the rat. The American journal of physiology, 1984, Volume: 247, Issue:3 Pt 1 Topics: Acetyltransferases; Amino-Acid N-Acetyltransferase; Ammonia; Animals; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Citrulline; Male; Mitochondria, Liver; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1984
[Ammonia metabolism during perinatal period--ontogenesis of enzymes in pyrimidine biosynthesis and urea cycle system]. Nihon Sanka Fujinka Gakkai zasshi, 1984, Volume: 36, Issue:12 Topics: Aging; Ammonia; Animals; Animals, Newborn; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Female; Fetus; Liver; Orotic Acid; Pregnancy; Pyrimidines; Rats; Rats, Inbred Strains; Urea	1984
Hyperammonemia and orotic aciduria in portacaval-shunted rats. The Journal of nutrition, 1984, Volume: 114, Issue:1 Topics: Ammonia; Ammonium Chloride; Animals; Arginine; Benzoates; Benzoic Acid; Liver; Liver Diseases; Male; Nitrogen; Organ Size; Orotic Acid; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Spleen; Urea	1984
Urea cycle function in the dog with emphasis on the role of arginine. The Journal of nutrition, 1984, Volume: 114, Issue:3 Topics: Age Factors; Ammonia; Animals; Arginine; Blood Glucose; Citrulline; Dogs; Ornithine; Orotic Acid; Urea; Vomiting	1984
Species comparison of the influence of ammonia on orotic acid and urea biosynthesis in liver. The Journal of nutrition, 1984, Volume: 114, Issue:3 Topics: Ammonia; Animals; Arginine; Cattle; Female; Liver; Male; Mice; Mice, Inbred ICR; Orotic Acid; Pyrimidines; Rats; Rats, Inbred Strains; Sheep; Species Specificity; Swine; Urea; Valine	1984
Orotic aciduria caused by feeding excess lysine to growing rats. The Journal of nutrition, 1981, Volume: 111, Issue:10 Topics: Ammonia; Animals; Arginine; Body Weight; Creatinine; Eating; Lysine; Male; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1981
The influence of excess lysine on urea cycle operation and pyrimidine biosynthesis. The Journal of nutrition, 1982, Volume: 112, Issue:10 Topics: Amino Acids; Ammonium Chloride; Animals; Arginase; Arginine; Dose-Response Relationship, Drug; Liver; Lysine; Orotic Acid; Rats; Rats, Inbred Strains; Urea	1982
Interaction between the urea cycle and the orotate pathway: studies with isolated hepatocytes. Archives of biochemistry and biophysics, 1983, Jul-01, Volume: 224, Issue:1 Topics: Ammonia; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Catalysis; In Vitro Techniques; Ligases; Liver; Male; Ornithine; Orotic Acid; Pyrimidines; Rats; Rats, Inbred Strains; Urea	1983
Activity of orotate metabolizing enzyme complex and various urea-cycle enzymes in mutant mice with ornithine transcarbamylase deficiency. Experientia, 1982, Mar-15, Volume: 38, Issue:3 Topics: Animals; Mice; Mice, Mutant Strains; Multienzyme Complexes; Ornithine Carbamoyltransferase Deficiency Disease; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Urea	1982
Argininemia: report of a new case and mechanisms of orotic aciduria and hyperammonemia. Advances in experimental medicine and biology, 1982, Volume: 153 Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child, Preschool; Female; Humans; Hyperargininemia; Ornithine; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Urea	1982
Comparison between amino acids and orotic acid analysis in the detection of urea cycle disorders in the Quebec Urinary Screening Program. Advances in experimental medicine and biology, 1982, Volume: 153 Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Chromatography, Thin Layer; Humans; Infant, Newborn; Mass Screening; Orotic Acid; Quebec; Urea	1982
Ammonia metabolism in dogs with portacaval shunts. Journal of pediatric surgery, 1982, Volume: 17, Issue:5 Topics: Ammonia; Animals; Arginine; Body Weight; Citrulline; Dogs; Female; Liver; Nitrogen; Organ Size; Orotic Acid; Portacaval Shunt, Surgical; Urea	1982
Ammonia metabolism in a family affected by hyperargininemia. Diabete & metabolisme, 1981, Volume: 7, Issue:1 Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Arginase; Arginine; Blood Urea Nitrogen; Erythrocytes; Female; Humans; Orotic Acid; Urea	1981
Orotic aciduria in lysinuric protein intolerance: dependence on the urea cycle intermediates. Pediatric research, 1981, Volume: 15, Issue:2 Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Carbamyl Phosphate; Child; Child, Preschool; Female; Heterozygote; Homozygote; Humans; Infant; Male; Orotic Acid; Proteins; Rats; Urea	1981
Effect of casein and starch infusion in the large intestine on nitrogen metabolism of growing swine. The Journal of nutrition, 1981, Volume: 111, Issue:8 Topics: Animals; Caseins; Digestion; Enterobacteriaceae; Feces; Female; Fermentation; Intestine, Large; Nitrogen; Orotic Acid; Protein Biosynthesis; Sheep; Starch; Swine; Urea	1981
Carrier detection of urea cycle disorders. Pediatrics, 1981, Volume: 68, Issue:3 Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Argininosuccinate Synthase; Citrulline; Female; Genetic Carrier Screening; Humans; Infant, Newborn; Male; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Pedigree; Pregnancy; Prenatal Diagnosis; Urea	1981
Nucleotide pool imbalances in the livers of patients with urea cycle disorders associated with increased levels of orotic aciduria. Biochemistry and molecular biology international, 1995, Volume: 35, Issue:3 Topics: Adenine Nucleotides; Carbamoyl-Phosphate Synthase (Ammonia); Humans; Liver; Metabolism, Inborn Errors; Nucleotides; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Tyrosine; Uracil Nucleotides; Urea	1995
Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline. The Journal of nutrition, 1994, Volume: 124, Issue:10 Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood Flow Velocity; Body Weight; Citrulline; Creatinine; Diet; Food; Glutamic Acid; Glutamine; Male; Ornithine; Orotic Acid; Proline; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Urea	1994
Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1994, Volume: 206, Issue:2 Topics: Animals; Arginine; Body Weight; Creatinine; Dietary Proteins; Female; Hypertrophy; Kidney; Organ Size; Orotic Acid; Rats; Rats, Sprague-Dawley; Urea	1994
Response of renal orotic acid and creatinine to treatments affecting metabolic protein supply of ruminants. Archiv fur Tierernahrung, 1995, Volume: 48, Issue:1-2 Topics: Allantoin; Animal Feed; Animals; Creatinine; Dietary Proteins; Kidney; Lysine; Male; Orotic Acid; Rumen; Ruminants; Sheep; Urea	1995
Cryptogenic hepatitis masking the diagnosis of ornithine transcarbamylase deficiency. Journal of pediatric gastroenterology and nutrition, 1996, Volume: 22, Issue:4 Topics: Absorption; Ammonia; Arginine; Child, Preschool; Citrulline; Diagnosis, Differential; Dietary Proteins; Female; Glutamine; Hepatitis; Humans; Infant; Lysine; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea	1996
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease. Journal of inherited metabolic disease, 1999, Volume: 22, Issue:2 Topics: Allopurinol; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolic Diseases; Mitochondria; Muscles; Orotic Acid; Predictive Value of Tests; Sensitivity and Specificity; Urea; Uridine	1999
Effect of lysine infusion on urea cycle in lysinuric protein intolerance. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:5 Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Basic; Amino Acids; Ammonia; Carrier Proteins; Female; Humans; Lysine; Male; Membrane Proteins; Middle Aged; Mutation; Orotic Acid; Urea	2000
Plasma urea-cycle-related amino acids, ammonium levels, and urinary orotic acid excretion in short-bowel patients managed with an oral diet. Clinical nutrition (Edinburgh, Scotland), 2003, Volume: 22, Issue:1 Topics: Adult; Aged; Amino Acids; Female; Humans; Male; Middle Aged; Orotic Acid; Quaternary Ammonium Compounds; Short Bowel Syndrome; Urea	2003
Influence of dietary arginine on sexual dimorphism of arginine metabolism in mice. The Journal of nutritional biochemistry, 2003, Volume: 14, Issue:6 Topics: Animals; Arginase; Arginine; Citrulline; Creatinine; Diet; Female; Kidney; Male; Mice; Muscle, Skeletal; Nitric Oxide Synthase; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Putrescine; Sex Characteristics; Urea	2003
Synthesis of ureido[14C] succinic acid and orotic[2-14C] acid from urea [14C]. Pharmaceutical bulletin, 1956, Volume: 4, Issue:6 Topics: Orotic Acid; Succinates; Succinic Acid; Urea	1956
ARGININE AS A PRECURSOR OF PYRIMIDINES IN STRAIN L-929 FIBROBLASTS INFECTED WITH PLEUROPNEUMONIA-LIKE ORGANISMS. The Journal of biological chemistry, 1964, Volume: 239 Topics: Arginase; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Connective Tissue; Fibroblasts; Glutamine; Ligases; Metabolism; Mycoplasma; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Phosphates; Phosphotransferases; Proline; Proteins; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Uracil; Urea; Ureohydrolases	1964
TRANSCARBAMYLASE ACTIVITY IN FETAL LIVER AND IN LIVER OF PARTIALLY HEPATECTOMIZED PARABIOTIC RATS. Archives of biochemistry and biophysics, 1965, Volume: 109 Topics: Cell Division; Enzyme Precursors; Erythrocyte Count; Fetus; Guinea Pigs; Hepatectomy; Ligases; Liver; Liver Diseases; Liver Regeneration; Nucleosides; Ornithine; Ornithine Carbamoyltransferase; Orotic Acid; Parabiosis; Pyrimidines; Rats; Research; Transferases; Uracil; Urea; Uridine	1965
Study of ureidosuccinic acid and related compounds in pyrimidine synthesis by Lactobacillus bulgaricus 09. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 79, Issue:4 Topics: Aspartic Acid; Lactobacillus; Orotic Acid; Pyrimidines; Urea	1952
Dietary arginine supplementation enhances the growth of milk-fed young pigs. The Journal of nutrition, 2004, Volume: 134, Issue:3 Topics: Amino Acids; Amino Acids, Essential; Ammonia; Animals; Animals, Newborn; Arginine; Blood Glucose; Body Weight; Dietary Supplements; Growth Hormone; Insulin; Milk; Orotic Acid; Swine; Urea	2004
Hazards associated with pregnancies and deliveries in lysinuric protein intolerance. Metabolism: clinical and experimental, 2006, Volume: 55, Issue:2 Topics: Adult; Amino Acid Transport Disorders, Inborn; Amino Acids, Diamino; Blood Pressure; Female; Hemoglobins; Humans; Infant, Newborn; Orotic Acid; Pregnancy; Pregnancy Complications; Toxemia; Urea	2006
Differentiation of 2-alkylthioorotic acids, methyl and ethyl 2-alkylthioorotates and hydrazides of 2-alkylthioorotic acids by using electron ionization mass spectra. European journal of mass spectrometry (Chichester, England), 2008, Volume: 14, Issue:1 Topics: Esters; Humans; Hydrazines; Isomerism; Orotic Acid; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds; Uracil; Urea; Vitamins	2008
Intermediates in the synthesis of orotic acid from oxalacetic ester and urea. Journal of the American Chemical Society, 1947, Volume: 69, Issue:3 Topics: Esters; Orotic Acid; Oxaloacetates; Oxaloacetic Acid; Urea	1947
The role of sodium in the salty taste of permeate. Journal of dairy science, 2014, Volume: 97, Issue:9 Topics: Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Citric Acid; Cytidine Monophosphate; Gas Chromatography-Mass Spectrometry; Guanosine Monophosphate; Hippurates; Inosine Monophosphate; Lactic Acid; Lactose; Milk; Orotic Acid; Potassium Chloride; Sodium Chloride; Taste; Urea; Uric Acid; Uridine Monophosphate; Volatile Organic Compounds	2014
Proximal urea cycle defects are challenging to detect with newborn screening: Results of a prospective pilot study using post-analytical tools. American journal of medical genetics. Part C, Seminars in medical genetics, 2022, Volume: 190, Issue:2 Topics: Amino Acids; Ammonia; Glutamine; Humans; Infant, Newborn; Lysine; Neonatal Screening; Orotic Acid; Pilot Projects; Prospective Studies; Urea	2022