urea and n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea

urea has been researched along with n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	5 (100.00)	2.80

Authors

Authors	Studies
Chugh, R; Fassnacht, M; Habra, MA; Ijzerman, MM; Jafarinasabian, P; Kebebew, E; Kroiss, M; Lin, VH; Mohideen, P; Naing, A; Schneider, BJ; Smith, DC	1
Hassan, A; Li, X; Long, T; Qi, X; Sun, Y	1
Auchus, RJ; Chang, AY; El-Maouche, D; Joyal, EG; Lin, VH; Merke, DP; Mohideen, P; Plaunt, MR; Turcu, AF; Vogiatzi, MG; Weintraub, L	1
Speiser, PW	1
Chalmers, P; Chen, X; Cioccoloni, G; Hughes, TA; Kiew, Y; Luo, X; Mwarzi, R; Poirot, M; Røberg-Larsen, H; Thorne, JL; Websdale, A; Wu, R; Xu, M; Zulyniak, MA	1

Reviews

1 review(s) available for urea and n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea

Article	Year
Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: A systematic review and meta-analysis of preclinical models. Biochemical pharmacology, 2022, Volume: 196 Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Cholesterol; Clinical Trials as Topic; Esterification; Humans; Organic Anion Transporters; Tumor Burden; Urea; Xenograft Model Antitumor Assays	2022

Article

Year

Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: A systematic review and meta-analysis of preclinical models.

Biochemical pharmacology, 2022, Volume: 196

Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Cholesterol; Clinical Trials as Topic; Esterification; Humans; Organic Anion Transporters; Tumor Burden; Urea; Xenograft Model Antitumor Assays

2022

Trials

2 trial(s) available for urea and n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea

Article	Year
A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma. Investigational new drugs, 2020, Volume: 38, Issue:5 Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Female; Humans; Male; Middle Aged; Sterol O-Acyltransferase; Tablets; Urea	2020
A Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia. The Journal of clinical endocrinology and metabolism, 2020, 08-01, Volume: 105, Issue:8 Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Biomarkers; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans; Middle Aged; Treatment Outcome; Urea; Young Adult	2020

Article

Year

A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma.

Investigational new drugs, 2020, Volume: 38, Issue:5

Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Female; Humans; Male; Middle Aged; Sterol O-Acyltransferase; Tablets; Urea

2020

A Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia.

The Journal of clinical endocrinology and metabolism, 2020, 08-01, Volume: 105, Issue:8

Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Biomarkers; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans; Middle Aged; Treatment Outcome; Urea; Young Adult

2020

Other Studies

2 other study(ies) available for urea and n-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea

Article	Year
Structure of nevanimibe-bound tetrameric human ACAT1. Nature, 2020, Volume: 581, Issue:7808 Topics: Cholesterol; Cryoelectron Microscopy; Histidine; Holoenzymes; Humans; Ligands; Models, Molecular; Protein Multimerization; Static Electricity; Sterol O-Acyltransferase; Urea	2020
Invited Commentary: A Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia. The Journal of clinical endocrinology and metabolism, 2020, 10-01, Volume: 105, Issue:10 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Humans; Urea	2020