urea has been researched along with n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Baxter, GS; Forbes, IT; Holland, V; Jones, GE; Murphy, OE | 1 |
| Bubar, MJ; Cunningham, KA; Filip, M | 1 |
| Distad, M; Farrugia, G; Gibbons, SJ; Ou, Y; Roeder, JL; Strege, PR; Szurszewski, JH; Wouters, MM | 1 |
| Dergacheva, O; Gorini, C; Griffioen, KJ; Kamendi, H; Mendelowitz, D; Wang, X | 1 |
| Cai, L; Hertz, L; Li, B; Nu, W; Peng, L; Zhang, H; Zhang, S | 1 |
| Hertz, L; Li, B; Li, M; Peng, L; Zhang, S | 1 |
| Furness, JB; Gale, JD; Himaki, D; Kawai, M; Kurebayashi, Y; Nagao, K; Ohashi-Doi, K | 1 |
| Bai, CF; Cao, W; Guo, HJ; Liu, JC; Liu, SB; Yang, Q; Yi, DH; Zhang, XN; Zhao, MG; Zhao, R | 1 |
| Burt, AD; Douglass, A; Ebrahimkhani, MR; Ellis, E; Jaffré, F; Lakey, AF; Mann, DA; Mann, J; Maroteaux, L; Moles, A; Murphy, LB; Oakley, F; Perugorria, MJ; White, SA; Wright, MC | 1 |
| Hutcheson, JD; Merryman, WD; Ryzhova, LM; Setola, V | 1 |
| Hattori, T; Muto, S; Nahata, M; Nakagawa, K; Ohnishi, S; Sadakane, C; Saegusa, Y; Sakamoto, N; Takeda, H; Yamada, C | 1 |
| Bloodworth, NC; Carrier, EJ; Chen, P; Gladson, S; Hutcheson, JD; Merryman, WD; Ryzhova, LM; Schroer, AK; Shay, S; West, JD | 1 |
| Bravo Sagua, R; Busso, D; Cárdenas, C; Cataldo, LR; Cortés, VA; Galgani, JE; Jaña, F; Llanos, P; Mizgier, ML; Olmos, P; Santos, JL | 1 |
| Distler, JHW; Ensminger, SM; Gocht, A; Heim, C; Ramsperger-Gleixner, M; Spriewald, B; Weyand, M | 1 |
| Gong, Z; Yan, C; Yang, Q | 1 |
| Agarwal, V; Chaturvedi, S; Misra, DP; Prasad, N; Rai, MK; Rastogi, K; Singh, H | 1 |
| Huo, FQ; Jia, H; Liu, H; Tang, JS; Wang, YY; Xu, WJ; Zhao, Y | 1 |
17 other study(ies) available for urea and n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea
| Article | Year |
|---|---|
N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea: a novel, high-affinity 5-HT2B receptor antagonist.
Topics: Animals; Humans; Indoles; Rats; Receptors, Serotonin; Serotonin Antagonists; Urea | 1995 |
Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluorobenzenes; Indoles; Male; Naphthyridines; Phenols; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists; Stimulation, Chemical; Urea | 2006 |
Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors.
Topics: Animals; Cell Proliferation; Cell Survival; Coculture Techniques; Indoles; Jejunum; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Myocytes, Smooth Muscle; Receptor, Serotonin, 5-HT2B; Ritanserin; RNA, Messenger; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Thiophenes; Urea | 2007 |
5-HT(2) receptor subtypes mediate different long-term changes in GABAergic activity to parasympathetic cardiac vagal neurons in the nucleus ambiguus.
Topics: Animals; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Heart; Hypoglossal Nerve; Indoles; Ketanserin; Medulla Oblongata; Neurons; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Urea; Vagus Nerve | 2007 |
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Astrocytes; Butadienes; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Fluoxetine; Gene Expression; Indoles; Maleimides; Mice; Nitriles; Phosphorylation; Piperidines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Quinazolines; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Signal Transduction; Substrate Specificity; Transcriptional Activation; Tyrphostins; Up-Regulation; Urea | 2008 |
Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Gene Expression Regulation; Indoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phospholipases A2; Phosphorylation; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Time Factors; Urea | 2009 |
A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats.
Topics: Analysis of Variance; Animals; Colon; Dose-Response Relationship, Drug; Hypersensitivity; Indoles; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Pain Measurement; Pain Threshold; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Restraint, Physical; Serotonin 5-HT2 Receptor Antagonists; Statistics, Nonparametric; Stress, Physiological; Trinitrobenzenesulfonic Acid; Urea | 2010 |
Role of 5-HT 2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calcium Channels, L-Type; Cardiomegaly; Cardiomyopathies; Caspase 3; Down-Regulation; Indoles; Myocytes, Cardiac; Naphthyridines; Norepinephrine; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Up-Regulation; Urea | 2010 |
Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chronic Disease; Electrophoresis, Polyacrylamide Gel; Hepatic Stellate Cells; Hepatocytes; Immunohistochemistry; Indoles; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Transforming Growth Factor beta1; Urea; Wound Healing | 2011 |
5-HT(2B) antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation.
Topics: Actins; Animals; Aortic Diseases; Aortic Valve; Calcinosis; Cell Differentiation; Cells, Cultured; Gene Expression; Indoles; Microfilament Proteins; Muscle Proteins; Myofibroblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Transport; Pyridines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Smad3 Protein; src-Family Kinases; Sus scrofa; Transcriptional Activation; Transforming Growth Factor beta1; Urea | 2012 |
Rikkunshito, a Japanese kampo medicine, ameliorates decreased feeding behavior via ghrelin and serotonin 2B receptor signaling in a novelty stress murine model.
Topics: Animals; Behavior, Animal; Chalcones; Drugs, Chinese Herbal; Eating; Enzyme Inhibitors; Feeding Behavior; Ghrelin; Humans; Indoles; Male; Medicine, Kampo; Mice; Quinolines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological; Urea | 2013 |
Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension.
Topics: Animals; Bone Morphogenetic Protein Receptors, Type II; Cell Movement; Cytoskeletal Proteins; Gene Expression Profiling; Gene Expression Regulation; Hypertension, Pulmonary; Indoles; Lung; Mice; Mice, Transgenic; Muscle Contraction; Muscle Proteins; Mutation; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Phosphorylation; Protein Transport; Receptor, Serotonin, 5-HT2B; Serotonin Antagonists; Signal Transduction; src-Family Kinases; Urea; Vascular Stiffness | 2016 |
Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Gene Expression Regulation; Glucose; Humans; Indoles; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mitochondria; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Receptors, Serotonin; Serotonin; Thiophenes; Urea | 2017 |
Effects of different serotonin receptor subtype antagonists on the development of cardiac allograft vasculopathy in murine aortic allografts.
Topics: Animals; Aorta; Cell Proliferation; Female; Graft Rejection; Heart Transplantation; Humans; Indoles; Lisuride; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Animal; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Succinates; Transendothelial and Transepithelial Migration; Transplantation, Homologous; Urea | 2018 |
Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish.
Topics: Animals; Animals, Genetically Modified; Hepatic Stellate Cells; Hepatocytes; Indoles; Liver; Liver Neoplasms; Macrophages; Neutrophils; Proto-Oncogene Proteins p21(ras); Receptor, Serotonin, 5-HT2B; Serotonin; Signal Transduction; Transforming Growth Factor beta1; Tumor Microenvironment; Up-Regulation; Urea; Zebrafish; Zebrafish Proteins | 2018 |
5-HT
Topics: Adult; Cells, Cultured; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Indoles; Lisuride; Phenotype; Phosphorylation; Receptor, Serotonin, 5-HT2B; Scleroderma, Systemic; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Skin; STAT3 Transcription Factor; Transforming Growth Factor beta1; Urea | 2018 |
Involvement of 5-HT2A, 5-HT2B and 5-HT2C receptors in mediating the ventrolateral orbital cortex-induced antiallodynia in a rat model of neuropathic pain.
Topics: Animals; Hyperalgesia; Indoles; Male; Neuralgia; Prefrontal Cortex; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Spiro Compounds; Sulfonamides; Urea | 2020 |