urea has been researched along with morphine in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (29.51) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (9.84) | 29.6817 |
| 2010's | 28 (45.90) | 24.3611 |
| 2020's | 9 (14.75) | 2.80 |
| Authors | Studies |
|---|---|
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Nordal, A; Paulsen, BS; Wold, JK | 1 |
| Fujimoto, JM; Peterson, RE | 3 |
| Chapman, AG | 1 |
| Doetsch, RN; Smith, JL | 1 |
| Apte, BK; Chaudhury, RR | 1 |
| Ducellier, G; Helie, J; Michelier, Y | 1 |
| Adamson, RH; Ben, M; Dixon, RL; Rall, DP | 1 |
| Smith, CM | 1 |
| Koe, BK; Weissman, A | 1 |
| Marchand, C | 1 |
| Denis, G; Marchand, C | 1 |
| Wong, SC; Yeung, DC | 1 |
| Lee, MA; Leng, ME; Tiernan, EJ | 1 |
| ZINNITZ, F | 1 |
| Hashimoto, S; Khotib, J; Miyatake, M; Nagumo, Y; Nakamachi, T; Narita, M; Sakurai, T; Shioda, S; Suzuki, T; Yanagisawa, M | 1 |
| Aoe, T; Kozikowski, A; Neale, JH; Saito, O; Sarva, J; Yamamoto, T | 1 |
| Dileone, RJ; Sarhan, M; Sharf, R | 1 |
| Kirouac, GJ; Li, S; Li, Y; Sui, N | 1 |
| DiLeone, RJ; Guarnieri, DJ; Sharf, R; Taylor, JR | 1 |
| Azizi, H; Mirnajafi-Zadeh, J; Rohampour, K; Semnanian, S | 1 |
| Hammock, BD; Inceoglu, B; Jones, PD; Liu, JY; Morisseau, C; Rose, TE; Sanborn, JR | 1 |
| Chen, X; Kirouac, GJ; Li, S; Li, Y; Qi, K; Sui, N; Wang, H | 1 |
| Azizi, H; Fathollahi, Y; Ranjbar-Slamloo, Y; Semnanian, S | 1 |
| Dehpour, AR; Esmaeili, B; Ghaffarpour, M; Javadi-Paydar, M; Mirbaha, H; Motiei-Langroudi, R; Tabaeizadeh, M; Tahsili-Fahadan, P | 1 |
| Azhdari-Zarmehri, H; Erami, E; Ghasemi-Dashkhasan, E; Haghparast, A; Rahmani, A; Semnanian, S | 1 |
| Azhdari-Zarmehri, H; Esmaeili, MH; Haghdoost-Yazdi, H; Sofiabadi, M | 1 |
| Fatahi, Z; Haghparast, A; Sarihi, A; Zarepour, L | 1 |
| Azizi, H; Javan, M; Mirnajafi-Zadeh, J; Mousavi, Y; Semnanian, S | 1 |
| Azizi, H; Ghaemi-Jandabi, M; Semnanian, S | 1 |
| Kumei, S; Miyagishi, S; Nozu, T; Ohhira, M; Okumura, T; Takakusaki, K | 1 |
| Cui, Y; Guo, SJ; Huang, ZZ; Jiang, JX; Liu, H; Xin, WJ; Zhang, XQ | 1 |
| Alijanpour, S; Tirgar, F; Zarrindast, MR | 1 |
| Ebrahimian, F; Haghparast, A; Naghavi, FS; Sadeghzadeh, F; Taslimi, Z; Yazdi, F | 1 |
| Azizi, H; Davoudi, M; Mirnajafi-Zadeh, J; Semnanian, S | 1 |
| Abdollahi, H; Azizi, H; Ghaemi-Jandabi, M; Semnanian, S | 1 |
| Farahmandfar, M; Kadivar, M; Rastipisheh, S | 1 |
| Azizi, H; Hooshmand, B; Javan, M; Semnanian, S | 1 |
| Doostmohammadi, J; Hooshmandi, M; Hosseinmardi, N; Janahmadi, M; Khakpai, F; Rohampour, K | 1 |
| Farahimanesh, S; Haghparast, A; Zarrabian, S | 1 |
| Bartram, S; Carlini, CR; Hasabe, M; Hedrich, R; Kerth, G; Ligabue-Braun, R; Mithöfer, A; Schöner, CR; Schöner, MG; Witte, CP; Yilamujiang, A; Zhu, A | 1 |
| Haghparast, A; Karimi-Haghighi, S; Mousavi, Z; Sahafzadeh, M | 1 |
| Farahimanesh, S; Haghparast, A; Karimi, S | 1 |
| Baranowska-Bosiacka, I; Gutowska, I; Kotlińska, J; Listos, J; Listos, P; Talarek, S; Tarnowski, M; Łupina, M | 1 |
| Assar, N; Haghparast, A; Mahmoudi, D; Mousavi, Z; Zarrabian, S | 1 |
| Benyhe, S; Bojarski, AJ; Buda, S; Bugno, R; Golembiowska, K; Kudla, L; Makuch, W; Przewlocka, B; Przewlocki, R; Skupio, U; Solecki, W; Wiktorowska, L; Wojtas, A; Zádor, F | 1 |
| Haghparast, A; Jamali, S; Motamedi, F; RayatSanati, K; Shirazy, M | 1 |
| Huang, T; Li, J; Zhao, Z | 1 |
| Gholami, M; Joghataei, MT; Komaki, A; Kourosh-Arami, M; Lavaie, M; Najafi, Z | 1 |
| Assar, N; Azizi, P; Haghparast, A; Katebi, SN; Mahmoudi, D; Mousavi, Z | 1 |
| Bojarski, AJ; Bugno, R; Kudla, L; Podlewska, S; Przewlocki, R | 1 |
| Bong, D; Floyd, C; Liao, S; Pino, MJ; Tan, K; Wu, C | 1 |
| Aghajani, N; Azizi, H; Pourhamzeh, M; Semnanian, S | 1 |
| Haghparast, A; Hassanlou, AA; Jamali, S; RayatSanati, K | 1 |
| Haghparast, A; Jamali, S; Zarrabian, S | 1 |
| Fennefrohn, B | 1 |
| Goleski-Reilly, C; Rule, AH | 1 |
| Kittrich, M | 1 |
1 review(s) available for urea and morphine
| Article | Year |
|---|---|
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; Flurazepam; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Light; Morphine; Muscimol; Myoclonus; Serotonin; Urea; Valproic Acid | 1986 |
60 other study(ies) available for urea and morphine
| Article | Year |
|---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Precursor incorporation experiments in Papaver alkaloid biosynthesis. II. Papaver somniferum L.
Topics: Codeine; Glycine; Morphine; Papaver; Phenylalanine; Plants, Medicinal; Thebaine; Urea | 1977 |
A study of absorption of compounds from the rat biliary tree by retrograde intrabiliary injection (RII).
Topics: Absorption; Aminohippuric Acids; Animals; Biliary Tract; Carbon Radioisotopes; Erythritol; Injections; Inulin; Male; Mannitol; Methanol; Morphine; Ouabain; Pharmaceutical Preparations; Procainamide; Rats; Sulfobromophthalein; Tetraethylammonium Compounds; Tritium; Urea | 1975 |
Increased "bile duct-pancreatic fluid" flow in rats pretreated with carbon tetrachloride.
Topics: Animals; Bile; Bile Ducts; Carbon Tetrachloride; Common Bile Duct; Inulin; Male; Morphine; Ouabain; Pancreatic Juice; Rats; Stimulation, Chemical; Urea | 1976 |
Motility in Pseudomonas fluorescens with special reference to survival advantage and negative chemotaxis.
Topics: Acetylcholine; Amobarbital; Chemotaxis; Chloramphenicol; Cocaine; Culture Media; Dicumarol; Dimethyl Sulfoxide; Flagella; Indoleacetic Acids; Locomotion; Microscopy, Phase-Contrast; Morphine; Phenols; Phenylalanine; Physostigmine; Pseudomonas; Pyridinium Compounds; Quinacrine; Strychnine; Surface-Active Agents; Urea | 1968 |
An isolated guinea pig kidney perfusion preparation for studying the effect of pharmacologically active substances.
Topics: Aldosterone; Angiotensin II; Animals; Diuresis; Epinephrine; Guanethidine; Guinea Pigs; Histamine; Hydrochlorothiazide; In Vitro Techniques; Kidney; Morphine; Norepinephrine; Organomercury Compounds; Perfusion; Regional Blood Flow; Reserpine; Serotonin; Urea; Vasopressins; Yohimbine | 1966 |
[Practical advice on the procedure to follow during intravenous cholangiography].
Topics: Biliary Tract Diseases; Cholangiography; Cholecystectomy; Cholecystography; Cholelithiasis; Contrast Media; Diet; Diuresis; Heart Diseases; Humans; Injections, Intravenous; Iodine; Jaundice; Kidney Failure, Chronic; Liver Function Tests; Methods; Morphine; Perfusion; Tomography; Urea | 1969 |
Retrograde intrabiliary injection: absorption of water and other compounds from the rat biliary tree.
Topics: Absorption; Animals; Bile; Biliary Tract; Carbon Isotopes; Erythritol; Injections; Inulin; Male; Mannitol; Methods; Morphine; Rats; Sulfobromophthalein; Tritium; Urea; Water | 1973 |
Toxicity and pharmacology of an unusual solvent-tetramethylurea.
Topics: Analgesics; Animals; Anticonvulsants; Antineoplastic Agents; Avoidance Learning; Cardiovascular System; Chlorpromazine; Haplorhini; Mice; Morphine; Solvents; Urea | 1966 |
The release of acetylcholine from rabbit hippocampus.
Topics: Acetylcholine; Animals; Carbon Isotopes; Electric Stimulation; Hippocampus; Morphine; Pentylenetetrazole; Rabbits; Urea | 1972 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
The diuretic and antidiuretic effect of morphine sulphate in rats.
Topics: Animals; Calcium; Diuresis; Female; Morphine; Potassium; Rats; Sodium; Urea; Urine; Water-Electrolyte Balance | 1970 |
Diuretic effect of chronic morphine treatment in rats.
Topics: Animals; Blood; Carbon Dioxide; Diuresis; Hydrogen-Ion Concentration; Kidney Concentrating Ability; Male; Morphine; Nalorphine; Natriuresis; Osmolar Concentration; Potassium; Rats; Urea; Urine; Vasopressins; Water-Electrolyte Balance | 1968 |
Effect of morphine on gluconeogenesis and ureogenesis in rat liver.
Topics: Amino Acids; Animals; Argininosuccinate Synthase; Bicarbonates; Carbamoyl-Phosphate Synthase (Ammonia); Gluconeogenesis; Glucose; Liver; Male; Morphine; Pyruvates; Rats; Urea | 1981 |
Retrospective study of the use of hydromorphone in palliative care patients with normal and abnormal urea and creatinine.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Creatinine; Female; Humans; Hydromorphone; Kidney; Male; Middle Aged; Morphine; Palliative Care; Retrospective Studies; Treatment Outcome; Urea | 2001 |
[The guaiacol-glycerin-ether effect ("Neuroton") in the Siamese fighting fish (Betta splendens) under the influence of adrenaline, acetylcholine, urea, saponin and morphine].
Topics: Acetylcholine; Animals; Epinephrine; Ether; Ethers; Fishes; Glycerol; Guaiacol; Leadership; Morphine; Muscle Relaxants, Central; Perciformes; Saponins; Urea | 1960 |
Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine.
Topics: Animals; Benzoxazoles; Conditioning, Operant; Desipramine; Dopamine; Female; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Intracellular Signaling Peptides and Proteins; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Microdialysis; Microinjections; Morphine; Motor Activity; Naphthyridines; Neuropeptides; Nucleus Accumbens; Orexins; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; RNA, Messenger; Tyrosine 3-Monooxygenase; Urea; Ventral Tegmental Area | 2006 |
Ketamine and N-acetylaspartylglutamate peptidase inhibitor exert analgesia in bone cancer pain.
Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Bone Neoplasms; Dexmedetomidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Mice; Mice, Inbred C3H; Morphine; Pain, Intractable; Protease Inhibitors; Urea | 2006 |
Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell.
Topics: Analysis of Variance; Animals; Benzoxazoles; Intracellular Signaling Peptides and Proteins; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naphthyridines; Narcotic Antagonists; Narcotics; Neuropeptides; Nucleus Accumbens; Orexins; Proto-Oncogene Proteins c-fos; Stilbamidines; Substance Withdrawal Syndrome; Urea; Ventral Tegmental Area | 2008 |
Orexin-A acts on the paraventricular nucleus of the midline thalamus to inhibit locomotor activity in rats.
Topics: Animals; Arousal; Behavior, Animal; Benzoxazoles; Grooming; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Midline Thalamic Nuclei; Morphine; Motor Activity; Naphthyridines; Narcotics; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sympathomimetics; Urea | 2009 |
Orexin mediates morphine place preference, but not morphine-induced hyperactivity or sensitization.
Topics: Animals; Benzoxazoles; Central Nervous System Agents; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Mutation; Naphthyridines; Narcotics; Neuropeptides; Orexin Receptors; Orexins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Space Perception; Time Factors; Urea | 2010 |
Antagonism of orexin type 1 receptors in the locus coeruleus attenuates signs of naloxone-precipitated morphine withdrawal in rats.
Topics: Animals; Benzoxazoles; Injections, Intraventricular; Locus Coeruleus; Male; Morphine; Morphine Dependence; Naloxone; Naphthyridines; Narcotic Antagonists; Narcotics; Orexin Receptors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance Withdrawal Syndrome; Urea | 2010 |
1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain.
Topics: Adamantane; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Epoxide Hydrolases; Humans; Male; Mice; Morphine; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Solubility; Structure-Activity Relationship; Urea | 2010 |
Orexins in the midline thalamus are involved in the expression of conditioned place aversion to morphine withdrawal.
Topics: Animals; Avoidance Learning; Benzoxazoles; Conditioning, Classical; Disease Models, Animal; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Midline Thalamic Nuclei; Morphine; Naloxone; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance Withdrawal Syndrome; Urea | 2011 |
Orexin receptor type-1 antagonist SB-334867 inhibits the development of morphine analgesic tolerance in rats.
Topics: Analgesics, Opioid; Animals; Benzoxazoles; Drug Tolerance; Male; Morphine; Naphthyridines; Nociception; Orexin Receptors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Urea | 2012 |
The differential effects of OX1R and OX2R selective antagonists on morphine conditioned place preference in naïve versus morphine-dependent mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Antigens, Surface; Benzoxazoles; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Isoquinolines; Male; Mice; Morphine; Morphine Dependence; Naphthyridines; Orexin Receptors; Pyridines; Receptors, Cell Surface; Receptors, Neuropeptide; Urea | 2013 |
Blockade of orexin receptor 1 attenuates the development of morphine tolerance and physical dependence in rats.
Topics: Animals; Benzoxazoles; Drug Tolerance; Male; Morphine; Naphthyridines; Opioid-Related Disorders; Orexin Receptors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Urea | 2012 |
Orexin receptor type-1 antagonist SB-334867 decreases morphine-induced antinociceptive effect in formalin test.
Topics: Analgesics; Animals; Benzoxazoles; Injections, Intraventricular; Morphine; Naphthyridines; Orexin Receptor Antagonists; Pain Measurement; Rats; Receptors, Neuropeptide; Urea | 2013 |
Blockade of orexin-1 receptors in the ventral tegmental area could attenuate the lateral hypothalamic stimulation-induced potentiation of rewarding properties of morphine.
Topics: Animals; Benzoxazoles; Carbachol; Cholinergic Agonists; Conditioning, Psychological; Hypothalamic Area, Lateral; Male; Morphine; Motor Activity; Naphthyridines; Narcotics; Orexin Receptor Antagonists; Rats; Rats, Wistar; Reward; Urea; Ventral Tegmental Area | 2014 |
Blockade of orexin type-1 receptors in locus coeruleus nucleus attenuates the development of morphine dependency in rats.
Topics: Animals; Benzoxazoles; Locus Coeruleus; Male; Morphine; Morphine Dependence; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Urea | 2014 |
Blockade of orexin type 1 receptors inhibits the development of morphine tolerance in lateral paragigantocellularis nucleus: an electrophysiological approach.
Topics: Animals; Benzoxazoles; Drug Tolerance; Male; Medulla Oblongata; Morphine; Naphthyridines; Neurons; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Urea | 2014 |
Antinociceptive action against colonic distension by brain orexin in conscious rats.
Topics: Analgesics; Animals; Benzoxazoles; Brain; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Electrodes, Implanted; Intracellular Signaling Peptides and Proteins; Male; Morphine; Naphthyridines; Neuropeptides; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pain Threshold; Physical Stimulation; Rats, Sprague-Dawley; Urea; Visceral Pain | 2015 |
Orexin A-mediated AKT signaling in the dentate gyrus contributes to the acquisition, expression and reinstatement of morphine-induced conditioned place preference.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzoxazoles; Choice Behavior; Conditioning, Psychological; Dentate Gyrus; Disease Models, Animal; Hypothalamic Area, Lateral; Male; Morphine; Naphthyridines; Opioid-Related Disorders; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Urea | 2016 |
Role of dorsal hippocampal orexin-1 receptors in memory restoration induced by morphine sensitization phenomenon.
Topics: Amnesia; Animals; Behavior, Animal; Benzoxazoles; CA1 Region, Hippocampal; Central Nervous System Sensitization; Male; Maze Learning; Morphine; Naphthyridines; Narcotics; Orexin Receptors; Rats; Rats, Wistar; Receptors, Neuropeptide; Spatial Memory; Urea | 2016 |
Differential roles of orexin receptors within the dentate gyrus in stress- and drug priming-induced reinstatement of conditioned place preference in rats.
Topics: Analgesics, Opioid; Animals; Benzoxazoles; Conditioning, Operant; Conditioning, Psychological; Dentate Gyrus; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Isoquinolines; Male; Morphine; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Pyridines; Rats; Rats, Wistar; Reward; Stress, Psychological; Swimming; Time Factors; Urea | 2016 |
The blockade of GABAA receptors attenuates the inhibitory effect of orexin type 1 receptors antagonist on morphine withdrawal syndrome in rats.
Topics: Animals; Benzoxazoles; Bicuculline; GABA-A Receptor Antagonists; Locus Coeruleus; Male; Microinjections; Morphine; Naloxone; Naphthyridines; Narcotic Antagonists; Orexin Receptor Antagonists; Orexin Receptors; Rats, Wistar; Substance Withdrawal Syndrome; Urea | 2016 |
The role of orexin type-1 receptors in the development of morphine tolerance in locus coeruleus neurons: An electrophysiological perspective.
Topics: Action Potentials; Animals; Benzoxazoles; Drug Tolerance; Locus Coeruleus; Male; Morphine; Naphthyridines; Neurons; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Urea | 2016 |
Blockade of dorsal hippocampal orexin-1 receptors impaired morphine-induced state-dependent learning.
Topics: Animals; Avoidance Learning; Benzoxazoles; Hippocampus; Male; Memory; Mice; Morphine; Motor Activity; Naphthyridines; Narcotics; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Urea | 2016 |
Intra-LC microinjection of orexin type-1 receptor antagonist SB-334867 attenuates the expression of glutamate-induced opiate withdrawal like signs during the active phase in rats.
Topics: Animals; Benzoxazoles; Disease Models, Animal; Glutamic Acid; Locus Coeruleus; Male; Microinjections; Morphine; Naphthyridines; Orexin Receptor Antagonists; Orexins; Rats, Wistar; Substance Withdrawal Syndrome; Urea | 2017 |
Antagonism of orexin type-1 receptors (OX1Rs) attenuates naloxone-precipitated morphine withdrawal syndrome in rat dorsal hippocampus.
Topics: Animals; Benzoxazoles; Hippocampus; Male; Microinjections; Morphine; Naloxone; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Urea | 2017 |
Role of orexin receptors in the ventral tegmental area on acquisition and expression of morphine-induced conditioned place preference in the rats.
Topics: Animals; Benzoxazoles; Conditioning, Operant; Isoquinolines; Male; Morphine; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Pyridines; Rats; Rats, Wistar; Reward; Urea; Ventral Tegmental Area | 2017 |
Coprophagous features in carnivorous Nepenthes plants: a task for ureases.
Topics: Cloning, Molecular; Gene Expression; Isotopes; Magnoliopsida; Nitrogen; Organic Chemicals; Phylogeny; Tandem Mass Spectrometry; Urea; Urease | 2017 |
Role of the orexin receptors within the nucleus accumbens in the drug priming-induced reinstatement of morphine seeking in the food deprived rats.
Topics: Animals; Benzoxazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Food Deprivation; Isoquinolines; Male; Morphine; Morphine Dependence; Naphthyridines; Narcotics; Nucleus Accumbens; Orexin Receptor Antagonists; Orexin Receptors; Pyridines; Rats, Wistar; Urea | 2018 |
Role of orexin-1 receptors in the dorsal hippocampus (CA1 region) in expression and extinction of the morphine-induced conditioned place preference in the rats.
Topics: Animals; Behavior, Animal; Benzoxazoles; CA1 Region, Hippocampal; Gene Expression Regulation; Male; Morphine; Naphthyridines; Orexin Receptors; Rats; Rats, Wistar; Urea | 2018 |
SB-334867 (an Orexin-1 Receptor Antagonist) Effects on Morphine-Induced Sensitization in Mice-a View on Receptor Mechanisms.
Topics: Animals; Astrocytes; Benzoxazoles; Brain; Male; Mice; Microglia; Morphine; Motor Activity; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Receptor, Adenosine A1; Receptor, Adenosine A2A; RNA, Messenger; Urea | 2018 |
Role of orexin-1 and -2 receptors within the nucleus accumbens in the acquisition of sensitization to morphine in rats.
Topics: Animals; Benzoxazoles; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; Drug Interactions; Drug Tolerance; Isoquinolines; Male; Morphine; Morphine Dependence; Naphthyridines; Nucleus Accumbens; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pyridines; Rats; Rats, Wistar; Reward; Urea | 2019 |
Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Injections, Intravenous; Injections, Spinal; Locomotion; Male; Mice; Mice, Inbred C57BL; Morphine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Structure-Activity Relationship; Thiophenes; Urea | 2019 |
Role of orexinergic receptors in the dentate gyrus of the hippocampus in the acquisition and expression of morphine-induced conditioned place preference in rats.
Topics: Animals; Behavior, Animal; Benzoxazoles; Conditioning, Classical; Dentate Gyrus; Isoquinolines; Male; Morphine; Naphthyridines; Narcotics; Orexin Receptor Antagonists; Orexin Receptors; Pyridines; Rats; Rats, Wistar; Reward; Urea | 2020 |
Molecular Dynamics Simulations to Investigate How PZM21 Affects the Conformational State of the μ-Opioid Receptor Upon Activation.
Topics: Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Ligands; Molecular Dynamics Simulation; Morphine; Pain; Receptors, Opioid, mu; Spiro Compounds; Thiophenes; Urea | 2020 |
Persistent effects of the orexin-1 receptor antagonist SB-334867 on naloxone precipitated morphine withdrawal symptoms and nociceptive behaviors in morphine dependent rats.
Topics: Animals; Behavior, Animal; Benzoxazoles; Disease Models, Animal; Morphine; Morphine Dependence; Naloxone; Naphthyridines; Narcotic Antagonists; Narcotics; Nociceptive Pain; Orexin Receptor Antagonists; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Urea | 2022 |
The orexin receptors in the ventral tegmental area are involved in the development of sensitization to expression of morphine-induced preference in rats.
Topics: Animals; Benzoxazoles; Brain; Carbachol; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; Drug-Seeking Behavior; Hypothalamic Area, Lateral; Isoquinolines; Male; Morphine; Naphthyridines; Nucleus Accumbens; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pyridines; Rats; Rats, Wistar; Reward; Urea; Ventral Tegmental Area | 2020 |
Molecular Modeling of µ Opioid Receptor Ligands with Various Functional Properties: PZM21, SR-17018, Morphine, and Fentanyl-Simulated Interaction Patterns Confronted with Experimental Data.
Topics: Animals; Fentanyl; Humans; Molecular Dynamics Simulation; Morphine; Receptors, Opioid; Thiophenes; Urea | 2020 |
Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation.
Topics: Allosteric Regulation; Animals; Aspartic Acid; Cluster Analysis; Conserved Sequence; Crystallization; Humans; Ligands; Mice; Molecular Dynamics Simulation; Morphine; Principal Component Analysis; Protein Conformation; Receptors, Opioid, mu; Signal Transduction; Structural Homology, Protein; Thiophenes; Tyrosine; Urea; Water | 2021 |
Central blockade of orexin type 1 receptors reduces naloxone induced activation of locus coeruleus neurons in morphine dependent rats.
Topics: Action Potentials; Analgesics, Opioid; Animals; Benzoxazoles; Injections, Intraperitoneal; Injections, Intraventricular; Locus Coeruleus; Male; Morphine; Morphine Dependence; Naloxone; Naphthyridines; Narcotic Antagonists; Neurons; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Urea | 2021 |
Blockade of orexin receptors in the hippocampal dentate gyrus reduced the extinction latency of morphine-induced place preference in male rats.
Topics: Animals; Benzoxazoles; Conditioning, Operant; Dentate Gyrus; Drug-Seeking Behavior; Extinction, Psychological; Isoquinolines; Male; Morphine; Naphthyridines; Narcotics; Orexin Receptor Antagonists; Pyridines; Rats; Rats, Wistar; Urea | 2021 |
Similar role of mPFC orexin-1 receptors in the acquisition and expression of morphine- and food-induced conditioned place preference in male rats.
Topics: Animals; Benzoxazoles; Conditioning, Operant; Drug-Seeking Behavior; Food; Male; Morphine; Morphine Dependence; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Prefrontal Cortex; Rats; Rats, Wistar; Reward; Urea | 2021 |
[Examinations of the amniotic fluid in the last weeks of pregnancy. II. Determination of glucose, uric acid, urea nitrogen, lactate dehydrogenase (LDH) and glutamic-oxaloacetic transaminase (GOT)].
Topics: Albumins; Amniotic Fluid; Apgar Score; Aspartate Aminotransferases; Bilirubin; Calcium; Cholesterol; Female; Fetal Death; Gestational Age; Glucose; Humans; L-Lactate Dehydrogenase; Meconium; Nitrogen; Parity; Phosphorus; Placenta Diseases; Pregnancy; Pregnancy Trimester, Third; Urea; Uric Acid | 1974 |
Carcinoembryonic antigen (CEA): separation of CEA-reacting molecules from tumor, fetal gut, meconium and normal colon.
Topics: Antigens, Neoplasm; Carcinoembryonic Antigen; Colon; Colonic Neoplasms; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Isoelectric Focusing; Meconium; Methods; Neoplasm Proteins; Proteins; Radioimmunoassay; Sodium Chloride; Temperature; Time Factors; Tissue Extracts; Urea | 1973 |
Our own experiences with the research on the amniotic fluid.
Topics: Amniotic Fluid; Creatinine; Female; Humans; Infant, Newborn; Labor, Obstetric; Maternal-Fetal Exchange; Meconium; Osmolar Concentration; Pregnancy; Urea; Water-Electrolyte Balance | 1971 |