urea has been researched along with mdl 100907 in 37 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (5.41) | 18.2507 |
2000's | 6 (16.22) | 29.6817 |
2010's | 24 (64.86) | 24.3611 |
2020's | 5 (13.51) | 2.80 |
Authors | Studies |
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Fuller, RW; Hemrick-Luecke, SK | 1 |
Marcoli, M; Maura, G; Raiteri, M; Tortarolo, M | 1 |
Ashby, CR; Katsumori, H; Minabe, Y; Watanabe, K | 1 |
Pitsikas, N; Sakellaridis, N | 1 |
Andersson, CM; Brann, MR; Burstein, ES; Davis, RE; Del Tredici, AL; Gardell, LR; Geyer, MA; Harvey, SC; Lameh, J; Makhay, M; Ott, TR; Piu, F; Powell, SB; Schiffer, HH; Schlienger, N; Son, TY; Thygesen, MB; Tolf, BR; Uldam, AK; Vanover, KE; Veinbergs, I; Weiner, DM | 1 |
Ashby, CR; Blackburn, TP; Suzuki, K | 1 |
Cai, L; Hertz, L; Li, B; Nu, W; Peng, L; Zhang, H; Zhang, S | 1 |
Hertz, L; Li, B; Li, M; Peng, L; Zhang, S | 1 |
Furness, JB; Gale, JD; Himaki, D; Kawai, M; Kurebayashi, Y; Nagao, K; Ohashi-Doi, K | 1 |
Horiguchi, M; Huang, M; Li, Z; Meltzer, HY; Neill, JC; Shahid, M; Snigdha, S | 1 |
Bai, CF; Cao, W; Guo, HJ; Liu, JC; Liu, SB; Yang, Q; Yi, DH; Zhang, XN; Zhao, MG; Zhao, R | 1 |
Ancoli-Israel, S; Davis, RE; van Kammen, DP; Vanover, KE; Weiner, DM | 1 |
Arnt, J; Ebdrup, BH; Glenthøj, B; Rasmussen, H | 1 |
Bonhaus, DW; McFarland, K; Price, DL | 2 |
Burt, AD; Douglass, A; Ebrahimkhani, MR; Ellis, E; Jaffré, F; Lakey, AF; Mann, DA; Mann, J; Maroteaux, L; Moles, A; Murphy, LB; Oakley, F; Perugorria, MJ; White, SA; Wright, MC | 1 |
Klodt, PM; Kudrin, VS; Narkevich, VB; Raevskiĭ, KS | 1 |
Hutcheson, JD; Merryman, WD; Ryzhova, LM; Setola, V | 1 |
Hattori, T; Muto, S; Nahata, M; Nakagawa, K; Ohnishi, S; Sadakane, C; Saegusa, Y; Sakamoto, N; Takeda, H; Yamada, C | 1 |
Meltzer, HY; Roth, BL | 1 |
Banks, ML | 1 |
Chi-Burris, K; Citrome, L; Demos, G; Norton, JC | 1 |
Ondo, WG; Panchal, SC | 1 |
Distler, JHW; Ensminger, SM; Gocht, A; Heim, C; Ramsperger-Gleixner, M; Spriewald, B; Weyand, M | 1 |
Agarwal, V; Chaturvedi, S; Misra, DP; Prasad, N; Rai, MK; Rastogi, K; Singh, H | 1 |
Jalal, B | 1 |
Ballard, C; Cummings, J; Foff, E; Norton, J; Owen, R; Stankovic, S; Tariot, P; Youakim, J | 1 |
Ballard, C; Coate, B; Stankovic, S; Youakim, JM | 1 |
Adler, CH; Alva, G; Black, KJ; Cooney, JW; Isaacson, S; Kremens, D; Menza, MA; Meyer, JM; Morrissette, DA; Nasrallah, H; Pahwa, R; Patkar, AA; Simuni, T; Stacy, M; Stahl, SM | 1 |
Canal, C; de la Cruz, J | 1 |
Fedora, R; Morton, R; Nasrallah, HA | 1 |
Boren, CB; Boren, RA | 1 |
Coate, B; Isaacson, SH; Norton, J; Stankovic, S | 1 |
Abler, V; Aldred, JL; Alva, G; Cantillon, M; Coate, B; DeKarske, D; Jacobi, L; Norton, JC; Nunez, R | 1 |
Dirks, B; Fava, M; Freeman, MP; Jha, MK; Liu, K; Papakostas, GI; Shelton, RC; Stankovic, S; Thase, ME; Trivedi, MH | 1 |
Atanasovski, D; Eriksson, E; Hagsäter, SM; Näslund, J; Pettersson, C; Pettersson, R | 1 |
Abbs, B; Arango, C; Bugarski-Kirola, D; Fava, M; Liu, IY; Nasrallah, H; Stankovic, S | 1 |
7 review(s) available for urea and mdl 100907
Article | Year |
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Serotonin 2A receptor antagonists for treatment of schizophrenia.
Topics: Antipsychotic Agents; Brain; Fluorobenzenes; Humans; Phenols; Piperidines; Positron-Emission Tomography; Receptor, Serotonin, 5-HT2A; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Urea | 2011 |
Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs.
Topics: Benzazepines; Diabetes Mellitus, Type 2; Heart Valve Diseases; Humans; Molecular Structure; Obesity; Parkinson Disease; Piperidines; Receptors, Serotonin; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Urea | 2013 |
Pimavanserin for the treatment of Parkinson's disease psychosis: number needed to treat, number needed to harm, and likelihood to be helped or harmed.
Topics: Clinical Trials as Topic; Humans; Numbers Needed To Treat; Parkinson Disease; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Urea | 2018 |
Treating Hallucinations and Delusions Associated With Parkinson's Disease Psychosis.
Topics: Antipsychotic Agents; Delusions; Hallucinations; Humans; Parkinson Disease; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Urea | 2018 |
The neuropharmacology of sleep paralysis hallucinations: serotonin 2A activation and a novel therapeutic drug.
Topics: Animals; Dopamine; Hallucinations; Hallucinogens; Humans; Lysergic Acid Diethylamide; Neuropharmacology; Piperidines; Psilocybin; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sleep; Sleep Paralysis; Urea | 2018 |
Pimavanserin: Potential Treatment For Dementia-Related Psychosis.
Topics: Alzheimer Disease; Clinical Trials as Topic; Dementia; Humans; Mental Status and Dementia Tests; Parkinson Disease; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Severity of Illness Index; Treatment Outcome; Urea | 2018 |
Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus.
Topics: Antiparkinson Agents; Antipsychotic Agents; Consensus; Drug Substitution; Humans; Off-Label Use; Parkinson Disease; Piperidines; Practice Guidelines as Topic; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Urea | 2018 |
6 trial(s) available for urea and mdl 100907
Article | Year |
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Pimavanserin tartrate, a 5-HT(2A) receptor inverse agonist, increases slow wave sleep as measured by polysomnography in healthy adult volunteers.
Topics: Adult; Aged; Double-Blind Method; Female; Human Experimentation; Humans; Male; Middle Aged; Patient Compliance; Piperidines; Placebo Effect; Polysomnography; Serotonin 5-HT2 Receptor Antagonists; Sleep; Urea | 2011 |
Pimavanserin in Alzheimer's Disease Psychosis: Efficacy in Patients with More Pronounced Psychotic Symptoms.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Nursing Homes; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome; Urea | 2019 |
Blinded SAPS-PD Assessment After 10 Weeks of Pimavanserin Treatment for Parkinson's Disease Psychosis.
Topics: Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Parkinson Disease; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Urea | 2020 |
An Open-Label, 8-Week Study of Safety and Efficacy of Pimavanserin Treatment in Adults with Parkinson's Disease and Depression.
Topics: Aged; Depression; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Parkinson Disease; Piperidines; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Serotonin and Noradrenaline Reuptake Inhibitors; Urea | 2020 |
Effect of Adjunctive Pimavanserin on Sleep/Wakefulness in Patients With Major Depressive Disorder: Secondary Analysis From CLARITY.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Middle Aged; Piperidines; Serotonin 5-HT2 Receptor Antagonists; Sleep Wake Disorders; Treatment Outcome; Urea; Young Adult | 2020 |
Pimavanserin for negative symptoms of schizophrenia: results from the ADVANCE phase 2 randomised, placebo-controlled trial in North America and Europe.
Topics: Adolescent; Adult; Double-Blind Method; Europe; Female; Humans; Male; Middle Aged; North America; Outcome Assessment, Health Care; Piperidines; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Urea; Young Adult | 2022 |
24 other study(ies) available for urea and mdl 100907
Article | Year |
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Involvement of 5-HT2A receptors in the elevation of rat serum corticosterone concentrations by quipazine and MK-212.
Topics: Animals; Corticosterone; Fluorobenzenes; Indoles; Male; Piperidines; Pyrazines; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Urea | 1996 |
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum: involvement of 5-hydroxytryptamine2C receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebellum; Cyclic GMP; Excitatory Amino Acid Agonists; Fluorobenzenes; Indoles; Male; N-Methylaspartate; Nitric Oxide; Organ Culture Techniques; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Urea; Yohimbine | 1997 |
The effect of the acute administration of various selective 5-HT receptor antagonists on focal hippocampal seizures in freely-moving rats.
Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Fluorobenzenes; Granisetron; Hippocampus; Indoles; Locomotion; Male; Piperazines; Piperidines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Seizures; Serotonin Antagonists; Severity of Illness Index; Urea | 2000 |
The 5-HT2C receptor antagonist RO 60-0491 counteracts rats' retention deficits in a recognition memory task.
Topics: Animals; Behavior, Animal; Discrimination, Psychological; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Motor Activity; Naphthalenes; Rats; Rats, Wistar; Recognition, Psychology; Retention, Psychology; Serotonin 5-HT2 Receptor Antagonists; Urea | 2005 |
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
Topics: Animals; Behavior, Animal; Biological Availability; Cloning, Molecular; Humans; Male; Mice; NIH 3T3 Cells; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Urea | 2006 |
The acute and chronic administration of the 5-HT(2B/2C) receptor antagonist SB-200646A significantly alters the activity of spontaneously active midbrain dopamine neurons in the rat: An in vivo extracellular single cell study.
Topics: Action Potentials; Animals; Dopamine; Electrophysiology; Indoles; Male; Mesencephalon; Neurons; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Time Factors; Urea | 2006 |
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Astrocytes; Butadienes; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Fluoxetine; Gene Expression; Indoles; Maleimides; Mice; Nitriles; Phosphorylation; Piperidines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Quinazolines; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Signal Transduction; Substrate Specificity; Transcriptional Activation; Tyrphostins; Up-Regulation; Urea | 2008 |
Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Gene Expression Regulation; Indoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phospholipases A2; Phosphorylation; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Time Factors; Urea | 2009 |
A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats.
Topics: Analysis of Variance; Animals; Colon; Dose-Response Relationship, Drug; Hypersensitivity; Indoles; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Pain Measurement; Pain Threshold; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Restraint, Physical; Serotonin 5-HT2 Receptor Antagonists; Statistics, Nonparametric; Stress, Physiological; Trinitrobenzenesulfonic Acid; Urea | 2010 |
Attenuation of phencyclidine-induced object recognition deficits by the combination of atypical antipsychotic drugs and pimavanserin (ACP 103), a 5-hydroxytryptamine(2A) receptor inverse agonist.
Topics: Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Drug Interactions; Drug Inverse Agonism; Female; Fluorobenzenes; Phencyclidine; Piperidines; Random Allocation; Rats; Rats, Long-Evans; Recognition, Psychology; Serotonin 5-HT2 Receptor Antagonists; Urea | 2010 |
Role of 5-HT 2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calcium Channels, L-Type; Cardiomegaly; Cardiomyopathies; Caspase 3; Down-Regulation; Indoles; Myocytes, Cardiac; Naphthyridines; Norepinephrine; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Up-Regulation; Urea | 2010 |
Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; Dyskinesias; Fenfluramine; Fluorobenzenes; Hyperkinesis; Male; Motor Activity; Oxidopamine; Parkinson Disease; Piperidines; Psychotic Disorders; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Sensory Gating; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Serotonin Receptor Agonists; Substantia Nigra; Tyrosine 3-Monooxygenase; Urea | 2011 |
Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chronic Disease; Electrophoresis, Polyacrylamide Gel; Hepatic Stellate Cells; Hepatocytes; Immunohistochemistry; Indoles; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Transforming Growth Factor beta1; Urea; Wound Healing | 2011 |
[Possible role of serotonin 5-HT2 receptors in mechanism of afobazole anxiolytic action: neurochemical study of inter-line differences in mice].
Topics: Animals; Anti-Anxiety Agents; Benzimidazoles; Biogenic Monoamines; Brain Chemistry; Drug Synergism; Indoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morpholines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Antagonists; Species Specificity; Urea | 2011 |
Pimavanserin, a 5-HT2A receptor inverse agonist, reverses psychosis-like behaviors in a rodent model of Alzheimer's disease.
Topics: Alzheimer Disease; Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Drug Inverse Agonism; Male; Mice; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Urea | 2012 |
5-HT(2B) antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation.
Topics: Actins; Animals; Aortic Diseases; Aortic Valve; Calcinosis; Cell Differentiation; Cells, Cultured; Gene Expression; Indoles; Microfilament Proteins; Muscle Proteins; Myofibroblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Transport; Pyridines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Smad3 Protein; src-Family Kinases; Sus scrofa; Transcriptional Activation; Transforming Growth Factor beta1; Urea | 2012 |
Rikkunshito, a Japanese kampo medicine, ameliorates decreased feeding behavior via ghrelin and serotonin 2B receptor signaling in a novelty stress murine model.
Topics: Animals; Behavior, Animal; Chalcones; Drugs, Chinese Herbal; Eating; Enzyme Inhibitors; Feeding Behavior; Ghrelin; Humans; Indoles; Male; Medicine, Kampo; Mice; Quinolines; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological; Urea | 2013 |
Effects of 7-day repeated treatment with the 5-HT2A inverse agonist/antagonist pimavanserin on methamphetamine vs. food choice in male rhesus monkeys.
Topics: Animals; Choice Behavior; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Inverse Agonism; Feeding Behavior; Food; Macaca mulatta; Male; Methamphetamine; Piperidines; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome; Urea | 2016 |
Effects of different serotonin receptor subtype antagonists on the development of cardiac allograft vasculopathy in murine aortic allografts.
Topics: Animals; Aorta; Cell Proliferation; Female; Graft Rejection; Heart Transplantation; Humans; Indoles; Lisuride; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Animal; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Succinates; Transendothelial and Transepithelial Migration; Transplantation, Homologous; Urea | 2018 |
5-HT
Topics: Adult; Cells, Cultured; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Indoles; Lisuride; Phenotype; Phosphorylation; Receptor, Serotonin, 5-HT2B; Scleroderma, Systemic; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Skin; STAT3 Transcription Factor; Transforming Growth Factor beta1; Urea | 2018 |
Can pimavanserin help patients with Parkinson disease psychosis?
Topics: Antipsychotic Agents; Humans; Parkinson Disease; Piperidines; Psychotic Disorders; Serotonin 5-HT2 Receptor Antagonists; Urea | 2019 |
Successful treatment of clozapine-nonresponsive refractory hallucinations and delusions with pimavanserin, a serotonin 5HT-2A receptor inverse agonist.
Topics: Adult; Aged; Antipsychotic Agents; Clozapine; Delusions; Drug Resistance; Female; Hallucinations; Humans; Male; Middle Aged; Piperidines; Psychotic Disorders; Retrospective Studies; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Urea; Young Adult | 2019 |
Charles Bonnet Syndrome Treated With Pimavanserin.
Topics: Aged, 80 and over; Charles Bonnet Syndrome; Humans; Male; Piperidines; Serotonin 5-HT2 Receptor Antagonists; Urea | 2019 |
A Complex Impact of Systemically Administered 5-HT2A Receptor Ligands on Conditioned Fear.
Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds; Conditioning, Classical; Fear; Fluorobenzenes; Ligands; Male; Methylamines; Piperidines; Psilocybin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Urea | 2021 |