urea and fluorouracil

urea has been researched along with fluorouracil in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199026 (50.00)18.7374
1990's7 (13.46)18.2507
2000's3 (5.77)29.6817
2010's11 (21.15)24.3611
2020's5 (9.62)2.80

Authors

AuthorsStudies
Levin, VA1
Fujiwara, H; Kai, J; Masuda, T; Nakamura, K; Ueda, I1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cargnin, S; Genazzani, AA; Massarotti, A; Pirali, T; Serafini, M1
James, LJ; Pardee, AB1
Wohlrab, W2
Carson, JA; Gormican, A1
Hagihara, Y; Igarashi, I; Ouchi, T; Takahashi, K; Takano, Y1
Bachert, P; Port, RE; Semmler, W1
Croisy, A; Guerquin-Kern, JL; Leteurtre, F; Lhoste, JM1
Armand, JP; Bernadou, J; Béteille, JP; Bon, M; Lopez, A; Malet-Martino, MC; Martino, R1
Bon, M; Cabanac, S; Dimicoli, JL; Malet-Martino, MC; Martino, R; Nedelec, JF1
Armand, JP; Bernadou, J; Lopez, A; Malet-Martino, MC; Martino, R1
Hahn, RG; Moertel, CG; Reitemeier, RJ1
Shapiro, WR2
Hoshino, T; Wilson, CB1
Boyd, TH; Cox, BJ; Komp, DM; Lyles, RL; Stoner, GE1
Bowie, M; Mountain, IM; Stock, CC; Teller, MN1
Burns, BC; Rutledge, F; Smith, JP; Soffar, S1
Hunt, DE; Pittillo, RF1
Falkson, G; Falkson, HC; van der Merwe, AM; van Dyk, JJ; van Eden, EB1
Hahn, RG; Moertel, CG; Reitemeier, RJ; Schutt, AJ1
Ambre, JJ; Fischer, LJ1
Gorgun, B; Watne, AL1
Bowie, M; Stock, CC; Teller, MN1
Dwyer, MR; Smillie, RM1
Andrean, BA; De Kloet, SR; Hendricks, DV1
Coffey, JJ1
Milner, JA; Sundaram, SG1
Kobayashi, S; Kumai, T; Nakura, H; Tanaka, M; Tateishi, T; Watanabe, M1
Götz, A; Hohenleutner, U; Kopera, D; Landthaler, M; Wach, F1
DUSCHINSKY, R; GABRIEL, T; GORDON, MP; LOZERON, HA; TAUTZ, W1
Alves, AP; Bezerra, DP; Costa-Lotufo, LV; de Alencar, NM; de Castro, FO; de Moraes, MO; Elmiro, FJ; Lima, MA; Lima, MW; Mesquita, RO; Pessoa, C; Silveira, ER1
Gerami, P; Guitart, J; Lacouture, ME; Reilly, LM1
Berenberg, JL; Christian, D; Delaune, R; Loprinzi, CL; Menon, SP; Pajon, ER; Qin, R; Rowland, KM; Satele, DV; Thomas, S; Wolf, SL1
Amidon, GL; Provoda, CJ; Tsume, Y1
Zhang, L; Zhou, J1
Al-Batran, SE; Bolz, G; Gencer, D; Hegewisch-Becker, S; Hofheinz, RD; Kronawitter, U; Loeffler, LM; Potenberg, J; Schneeweiss, A; Schulz, H; Stahl, M; Tauchert, F1
Cameron, A; Charles, BG; Duley, JA; George, R; Harris, M; Helsby, N; Mead, S; Ni, M; Norris, RL; Shannon, C; Sheffield, L; van Kuilenburg, AB1
Burkholder, I; Hofheinz, RD; Schneeweiss, A1
Chiba, T; Ishiki, H; Iwase, S; Kinkawa, J; Shimada, N; Tojo, A; Watanabe, A1
Dai, G; Duan, Y; Shi, LH; Sun, ZP; Wang, XJ; Xu, WF; Zhang, J; Zhang, XR1
Bano, N; Ikram, R1
Al-Aqbi, SS; Alexandrou, C; Andreadi, C; Blades, M; Boyle, W; Brown, K; Cheng, PN; Higgins, JA; Howells, LM; Karmokar, A; Luo, JL; Moore, DA; Murray, GI; Rufini, A; Thomas, A; Viskaduraki, M1
Huang, H; Liao, J1
Boige, V; Boilève, A; Chouchana, L; Ducreux, M; Gaboriau, L; Hillaire-Buys, D; Hollebecque, A; Jozwiak, M; Lillo-Le Louët, A; Malka, D; Thomas, L1
Abdelmeniem, IM; El Eryan, IM; Fouda, I; Nofal, A; Omar, SS1
Andersen, F; Bjerring, P; Haedersdal, M; Lerche, CM; Pihl, C1

Reviews

3 review(s) available for urea and fluorouracil

ArticleYear
Essential Medicinal Chemistry of Essential Medicines.
    Journal of medicinal chemistry, 2020, 09-24, Volume: 63, Issue:18

    Topics: Administration, Oral; Chemistry, Pharmaceutical; Drugs, Essential; Formularies as Topic; Humans; Injections; Molecular Structure; Stereoisomerism; World Health Organization

2020
[Porokeratosis Mibelli gigantea: case report and literature review].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:6

    Topics: Acitretin; Aged; Calcitriol; Dermatologic Agents; Drug Combinations; Female; Fluorouracil; Humans; Porokeratosis; Tretinoin; Urea; Vitamin A

1999
Improving the efficacy of photodynamic therapy for actinic keratosis: A comprehensive review of pharmacological pretreatment strategies.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 43

    Topics: Aminolevulinic Acid; Diclofenac; Fluorouracil; Humans; Keratosis, Actinic; Photochemotherapy; Photosensitizing Agents; Retinoids; Salicylic Acid; Treatment Outcome; Urea; Vitamin D

2023

Trials

4 trial(s) available for urea and fluorouracil

ArticleYear
Placebo-controlled trial to determine the effectiveness of a urea/lactic acid-based topical keratolytic agent for prevention of capecitabine-induced hand-foot syndrome: North Central Cancer Treatment Group Study N05C5.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-10, Volume: 28, Issue:35

    Topics: Administration, Topical; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Double-Blind Method; Drug Combinations; Female; Fluorouracil; Foot Dermatoses; Hand Dermatoses; Humans; Keratolytic Agents; Lactic Acid; Male; Middle Aged; Neoplasms; Syndrome; Urea

2010
Mapisal Versus Urea Cream as Prophylaxis for Capecitabine-Associated Hand-Foot Syndrome: A Randomized Phase III Trial of the AIO Quality of Life Working Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Aug-01, Volume: 33, Issue:22

    Topics: Administration, Cutaneous; Adult; Aged; Antimetabolites, Antineoplastic; Antioxidants; Breast Neoplasms; Capecitabine; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Neoplasms; Germany; Hand-Foot Syndrome; Humans; Incidence; Keratolytic Agents; Male; Middle Aged; Ointments; Primary Prevention; Quality of Life; Severity of Illness Index; Skin Cream; Surveys and Questionnaires; Time Factors; Treatment Failure; Urea

2015
Towards a test to predict 5-fluorouracil toxicity: Pharmacokinetic data for thymine and two sequential metabolites following oral thymine administration to healthy adult males.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Jan-01, Volume: 81

    Topics: Adult; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Male; Middle Aged; Models, Biological; Saliva; Thymine; Urea

2016
Topical calcipotriol combined with urea 20% versus intralesional injection of triamcinolone acetonide, 5-fluorouracil, and methotrexate in the treatment of nail psoriasis: A comparative study.
    Dermatologic therapy, 2022, Volume: 35, Issue:9

    Topics: Calcitriol; Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Methotrexate; Nail Diseases; Psoriasis; Treatment Outcome; Triamcinolone Acetonide; Urea

2022

Other Studies

45 other study(ies) available for urea and fluorouracil

ArticleYear
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Blood-Brain Barrier; Chromatography, Gel; Hydrogen Bonding; Micelles; Permeability; Solubility; Thermodynamics

1996
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Selective killing of transformed baby hamster kidney (BHK) cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:12

    Topics: Antibiotics, Antineoplastic; Caffeine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cyclohexanones; Cycloheximide; Fluorouracil; Piperidones; Polyomavirus; Puromycin; Urea

1975
[Effect of urea on the mechanism of percutaneous permeation].
    Dermatologica, 1979, Volume: 159, Issue:6

    Topics: Animals; Autoradiography; Drug Therapy, Combination; Epidermis; Fluorouracil; Guinea Pigs; Skin Absorption; Skin Diseases; Sodium Chloride; Urea

1979
Taste acuity and food attitudes of selected patients with cancer.
    Journal of the American Dietetic Association, 1977, Volume: 70, Issue:4

    Topics: Adult; Aged; Attitude to Health; Breast Neoplasms; Colonic Neoplasms; Diet; Female; Fluorouracil; Food Preferences; Humans; Hydrochloric Acid; Male; Middle Aged; Sodium Chloride; Sucrose; Taste; Taste Threshold; Urea

1977
[Therapeutical action of urea on the skin (author's transl)].
    Dermatologica, 1977, Volume: 155, Issue:2

    Topics: Animals; Cell Division; DNA; Fluorouracil; Guinea Pigs; Skin; Time Factors; Urea

1977
Synthesis and antitumor activity of poly(ethylene glycol)s linked to 5-fluorouracil via a urethane or urea bond.
    Drug design and discovery, 1992, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Female; Fluorouracil; Leukemia P388; Mice; Polyethylene Glycols; Urea; Urethane

1992
Kinetic modeling of in vivo--nuclear magnetic resonance spectroscopy data: 5-fluorouracil in liver and liver tumors.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:5

    Topics: Adult; Aged; beta-Alanine; Female; Fluorine; Fluorouracil; Humans; Least-Squares Analysis; Liver; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Middle Aged; Urea

1991
pH dependence of 5-fluorouracil uptake observed by in vivo 31P and 19F nuclear magnetic resonance spectroscopy.
    Cancer research, 1991, Oct-15, Volume: 51, Issue:20

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta-Alanine; Fibrosarcoma; Fluorine; Fluorouracil; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Phosphorus; Rats; Rats, Inbred Strains; Urea

1991
Evidence for the importance of 5'-deoxy-5-fluorouridine catabolism in humans from 19F nuclear magnetic resonance spectrometry.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 2

    Topics: Aged; Antineoplastic Agents; beta-Alanine; Female; Floxuridine; Fluorouracil; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Urea

1986
Direct 19F NMR spectroscopic observation of 5-fluorouracil metabolism in the isolated perfused mouse liver model.
    NMR in biomedicine, 1988, Volume: 1, Issue:3

    Topics: Animals; beta-Alanine; Fluorouracil; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Mice; Urea

1988
Complete urinary excretion profile of 5-fluorouracil during a six-day chemotherapeutic schedule, as resolved by 19F nuclear magnetic resonance.
    Clinical chemistry, 1985, Volume: 31, Issue:6

    Topics: beta-Alanine; Fluorine; Fluorouracil; Humans; Magnetic Resonance Spectroscopy; Radioisotopes; Urea

1985
Combination chemotherapy in gastrointestinal cancer.
    Cancer research, 1970, Volume: 30, Issue:5

    Topics: Adenocarcinoma; Adult; Alopecia; Appendiceal Neoplasms; Diarrhea; Drug Eruptions; Fluorouracil; Gallbladder Neoplasms; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Leukopenia; Liver Neoplasms; Mitomycins; Nausea; Nitroso Compounds; Pancreatic Neoplasms; Stomach Neoplasms; Stomatitis; Thrombocytopenia; Urea; Vomiting

1970
Studies on the chemotherapy of experimental brain tumors: evaluation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, vincristine, and 5-fluorouracil.
    Journal of the National Cancer Institute, 1971, Volume: 46, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cyclophosphamide; Disease Models, Animal; Ependymoma; Evaluation Studies as Topic; Fluorouracil; Glioma; Injections, Intraperitoneal; Male; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Plicamycin; Urea; Vincristine

1971
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
    Journal of neurosurgery, 1969, Volume: 31, Issue:6

    Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Fluorouracil; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Spinal; Mechlorethamine; Methotrexate; Nitroso Compounds; Thiotepa; Time Factors; Urea; Vincristine

1969
Chemotherapy and immunity to cancer.
    Clinical bulletin, 1974, Volume: 4, Issue:4

    Topics: Allyl Compounds; Aniline Compounds; Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Immunity; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasms; Urea

1974
The effect of cancer chemotherapeutic agents on fibrin formation and stabilization in vitro.
    Pediatric research, 1974, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Asparaginase; Blood Coagulation Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Electric Conductivity; Factor XIII; Fibrin; Fibrinolysis; Fluorouracil; Humans; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Mechlorethamine; Methotrexate; Microscopy, Electron; Nitrogen Mustard Compounds; Solubility; Triazenes; Urea; Vinblastine; Vincristine

1974
Combination chemotherapy of advanced murine myeloma and subsequent resistance to tumor cell challenge.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:3

    Topics: Allyl Compounds; Aniline Compounds; Animals; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Graft Rejection; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Nitrogen Mustard Compounds; Plasmacytoma; Transplantation, Homologous; Urea

1974
Systemic chemotherapy for carcinoma of the cervix.
    American journal of obstetrics and gynecology, 1967, Mar-15, Volume: 97, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms

1967
Killing of cells in bacterial colonies.
    Applied microbiology, 1967, Volume: 15, Issue:2

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Azaserine; Chloramphenicol; Enterococcus faecalis; Escherichia coli; Fluorouracil; Kinetics; Methotrexate; Nitroso Compounds; Penicillin G; Urea

1967
5-Fluorouracil (5-Fu; NSC-19893), 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388), vincristine (NSC-67574), and 1,3-bis(2-chloroethyl)-2-nitrosourea (BCNU; NSC-409962) given concomitantly in the treatment of solid tumors in man.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:1

    Topics: Adult; Aged; Alkylating Agents; Amides; Carmustine; Drug Combinations; Female; Fluorouracil; Humans; Imidazoles; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nitroso Compounds; Triazenes; Urea; Vincristine

1972
Sequential 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) and 5-fluorouracil (NSC 19893) therapy of gastrointestinal cancer.
    Cancer research, 1972, Volume: 32, Issue:6

    Topics: Cyclohexanes; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leukopenia; Nitroso Compounds; Nitrosourea Compounds; Time Factors; Urea; Vomiting

1972
The effect of prednisolone and other factors on the catabolism of 5-fluorouracil in rats.
    The Journal of laboratory and clinical medicine, 1971, Volume: 78, Issue:3

    Topics: Animals; Autoradiography; Carbon Dioxide; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Ion Exchange; Drug Interactions; Fluorine; Fluorouracil; Male; Phenobarbital; Prednisolone; Propionates; Rats; Urea

1971
Skin homograft survival in cancer chemotherapy patients.
    Cancer, 1966, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Carbamates; Female; Fluorouracil; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasms; Skin Transplantation; Transplantation, Homologous; Urea

1966
Plasma cell tumors in experimental chemotherapy: consequence of dose variation on host survival and paraprotein synthesis.
    Journal of the National Cancer Institute, 1970, Volume: 45, Issue:6

    Topics: Aniline Compounds; Animals; Blood Protein Disorders; Blood Protein Electrophoresis; Bloodletting; Cyclophosphamide; Fluorouracil; Mice; Neoplasm Transplantation; Nitrogen Mustard Compounds; Plasmacytoma; Serum Globulins; Urea

1970
A light-induced beta-1,3-glucan breakdown associated with the differentiation of chloroplasts in Euglena gracilis.
    Biochimica et biophysica acta, 1970, Sep-01, Volume: 216, Issue:2

    Topics: Animals; Cell Differentiation; Chloramphenicol; Chloroplasts; Cycloheximide; Darkness; Euglena; Fluorouracil; Glucose; Glucosyltransferases; Glycoside Hydrolases; Light; Photosynthesis; Polysaccharides; Radiation Effects; Urea

1970
Further studies on chemotherapy of experimental brain tumors.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Ependymoma; Fluorouracil; Glioma; Mice; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Prognosis; Urea; Vincristine

1970
Effects of cycloheximide and 5-fluorouracil on formation of low-molecular-weight ribonucleic acid in yeast.
    Journal of bacteriology, 1969, Volume: 97, Issue:2

    Topics: Adenine; Carbon Isotopes; Chromatography; Chromatography, Gel; Cycloheximide; Fluorouracil; Leucine; Methionine; Nucleic Acid Denaturation; Nucleotides; Phosphates; Phosphorus Isotopes; Ribosomes; RNA; RNA, Transfer; Saccharomyces; Urea

1969
Inducible synthesis of bacterial luciferase: specificity and kinetics of induction.
    Journal of bacteriology, 1967, Volume: 94, Issue:5

    Topics: Amines; Amino Acids; Ammonium Chloride; Arginine; Azo Compounds; Bacteria; Bacterial Proteins; Carbamates; Carbon Isotopes; Chloramphenicol; Enzyme Induction; Fluorine; Fluorouracil; Guanidines; Kinetics; Light; Luciferases; Marine Biology; Nitrates; Phenylalanine; Propylamines; Puromycin; RNA, Messenger; Urea

1967
Diallyl disulfide suppresses the growth of human colon tumor cell xenografts in athymic nude mice.
    The Journal of nutrition, 1996, Volume: 126, Issue:5

    Topics: Administration, Oral; Allyl Compounds; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Division; Colonic Neoplasms; Disulfides; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Injections, Intraperitoneal; Leukocytes; Mice; Mice, Nude; Neoplasm Transplantation; Plant Oils; Transplantation, Heterologous; Tumor Cells, Cultured; Urea

1996
Sex- or age-related differences were not detected in the activity of dihydropyrimidine dehydrogenase from rat liver.
    Pharmacological research, 1997, Volume: 35, Issue:2

    Topics: Aging; Animals; Body Weight; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Liver; Male; Organ Size; Oxidoreductases; Rats; Rats, Sprague-Dawley; Sex Factors; Urea

1997
THE PHOTOCHEMISTRY OF 5-FLUOROURACIL.
    Biochemistry, 1964, Volume: 3

    Topics: Aldehydes; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Crystallization; Fluorouracil; Photochemistry; Radiometry; Research; Spectrum Analysis; Ultraviolet Rays; Urea

1964
In vitro and in vivo antitumor effect of 5-FU combined with piplartine and piperine.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:2

    Topics: Alanine Transaminase; Alkaloids; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Benzodioxoles; Cell Proliferation; Dose-Response Relationship, Drug; Female; Fluorouracil; HL-60 Cells; Humans; Inhibitory Concentration 50; Kidney; Leukopenia; Liver; Mice; Piperidines; Piperidones; Polyunsaturated Alkamides; Sarcoma 180; Urea

2008
Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:11

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Female; Fluorouracil; Foot Dermatoses; Hand Dermatoses; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Male; Middle Aged; Niacinamide; Nicotinic Acids; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib; Urea

2008
The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Apr-15, Volume: 879, Issue:13-14

    Topics: Analysis of Variance; Antimetabolites, Antineoplastic; beta-Alanine; Cell Extracts; Cell Line, Tumor; Chromatography, High Pressure Liquid; Floxuridine; Fluorouracil; Humans; Linear Models; Mass Spectrometry; Reproducibility of Results; Uracil; Urea

2011
Structure and properties of β-cyclodextrin/cellulose hydrogels prepared in NaOH/urea aqueous solution.
    Carbohydrate polymers, 2013, Apr-15, Volume: 94, Issue:1

    Topics: Antimetabolites, Antineoplastic; beta-Cyclodextrins; Cellulose; Drug Carriers; Fluorouracil; Gossypium; Hydrogels; Kinetics; Plant Extracts; Serum Albumin, Bovine; Sodium Hydroxide; Solutions; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Surface Properties; Urea

2013
Reply to S. Iwase et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Feb-01, Volume: 34, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antioxidants; Deoxycytidine; Female; Fluorouracil; Hand-Foot Syndrome; Humans; Keratolytic Agents; Male; Primary Prevention; Quality of Life; Urea

2016
Mapisal Versus Urea Cream as Prophylaxis for Capecitabine-Associated Hand-Foot Syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Feb-01, Volume: 34, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antioxidants; Deoxycytidine; Female; Fluorouracil; Hand-Foot Syndrome; Humans; Keratolytic Agents; Male; Primary Prevention; Quality of Life; Urea

2016
Aminopeptidase N inhibitor 4cc synergizes antitumor effects of 5-fluorouracil on human liver cancer cells through ROS-dependent CD13 inhibition.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 76

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 Antigens; Cell Line, Tumor; Drug Synergism; Female; Fluorouracil; Humans; Hydroxamic Acids; Leucine; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Urea; Xenograft Model Antitumor Assays

2015
Histopathological and biochemical assessment of kidney damage in albino wistar rats treated with cytotoxic platinum compounds in combination with 5-FU.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cisplatin; Creatinine; Fluorouracil; Kidney; Kidney Diseases; Oxaliplatin; Rats, Wistar; Urea

2017
Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
    Scientific reports, 2018, 08-14, Volume: 8, Issue:1

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Arginase; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Colon; Colorectal Neoplasms; Drug Interactions; Drug Synergism; Feasibility Studies; Female; Fluorouracil; Follow-Up Studies; Humans; Hydrolases; Inhibitory Concentration 50; Kaplan-Meier Estimate; Male; Mice; Ornithine Carbamoyltransferase; Oxaliplatin; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Treatment Outcome; Urea; Xenograft Model Antitumor Assays

2018
A fungal chitin derived from Hericium erinaceus residue: Dissolution, gelation and characterization.
    International journal of biological macromolecules, 2020, Jun-01, Volume: 152

    Topics: Biocompatible Materials; Butadienes; Chitin; Drug Delivery Systems; Elastomers; Fluorouracil; Hericium; Hydrogels; Kinetics; Sodium Hydroxide; Solubility; Solvents; Styrenes; Urea; Water

2020
5-Fluorouracil-induced hyperammonaemic encephalopathy: A French national survey.
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 129

    Topics: Aged; Ammonia; Antimetabolites, Antineoplastic; Brain Diseases; Citric Acid Cycle; Dose-Response Relationship, Drug; Female; Fluorouracil; France; Humans; Hyperammonemia; Incidence; Male; Middle Aged; Neoplasms; Pharmacovigilance; Retrospective Studies; Treatment Outcome; Urea

2020