urea has been researched along with dmp 450 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bacheler, LT; De Lucca, GV; Jacobs, K; Jadhav, PK; Kaltenbach, RF; Klabe, RM; Meyer, DT; Nugiel, DA; Patel, M; Rayner, MM; Seitz, SP; Smyser, TE; Worley, T | 1 |
| Grubb, MF; Krauthauser, CL; Robinson, CA; Shum, L; White, SJ | 1 |
| Aldrich, PE; Bacheler, LT; Chang, CH; Erickson-Viitanen, S; Eyermann, CJ; Garber, S; Grubb, M; Hodge, CN; Jackson, DA; Jadhav, PK; Korant, B; Lam, PY; Maurin, MB; Meek, JL; Otto, MJ; Rayner, MM; Reid, C; Sharpe, TR; Shum, L; Winslow, DL | 1 |
| Ala, PJ; Chang, CH; DeLoskey, RJ; Duke, JL; Hodge, CN; Huston, EE; Klabe, RM; Korant, BD; Lam, PY; McCabe, DD; Rizzo, CJ | 1 |
| Cordova, B; Jackson, DA; Rayner, MM | 1 |
| Ala, PJ; Chang, CH; DeLoskey, RJ; Duke, JL; Eyermann, CJ; Hodge, CN; Huston, EE; Jadhav, PK; Lam, PY; Lewandowski, FA; McCabe, DD; Schadt, MC; Weber, PC | 1 |
| Bacheler, LT; Cordova, B; De Lucca, GV; Erickson-Viitanen, S; Garber, S; Kim, UT; Klabe, RM; Ko, SS; Lam, GN; Liang, J; Logue, KA; Trainor, GL; Wright, MR | 1 |
| Aungst, BJ; De Lucca, GV; Erickson-Viitanen, S; Jadhav, PK; Lam, PY; Waltermire, RE | 1 |
| Bacheler, LT; Cordova, BC; Erickson-Viitanen, S; Klabe, RM; Patel, M; Rayner, MM; Seitz, SP | 1 |
| Maurin, MB; Vickery, RD | 1 |
| Aungst, BJ; Bulgarelli, JP; Nguyen, NH; Oates-Lenz, K | 1 |
| Hylton, KG; Main, AD; McElwee-White, L | 1 |
| Sussman, F; Vilar, S; Villaverde, MC | 1 |
| Li, P; Wang, H; Wang, S; Yan, H | 1 |
1 review(s) available for urea and dmp 450
| Article | Year |
|---|---|
De novo design and discovery of cyclic HIV protease inhibitors capable of displacing the active-site structural water molecule.
Topics: Animals; Azepines; Binding Sites; Drug Design; HIV Protease; HIV Protease Inhibitors; Humans; Molecular Conformation; Urea | 1998 |
13 other study(ies) available for urea and dmp 450
| Article | Year |
|---|---|
Preparation and structure-activity relationship of novel P1/P1'-substituted cyclic urea-based human immunodeficiency virus type-1 protease inhibitors.
Topics: Azepines; Binding Sites; Cell Line; Cell Survival; Crystallography, X-Ray; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Structure; Protein Binding; Structure-Activity Relationship; Urea | 1996 |
Determination of a HIV protease inhibitor (DMP 450) in animal and human plasma by solid-phase extraction and high-performance liquid chromatography.
Topics: Acetonitriles; Animals; Azepines; Chromatography, High Pressure Liquid; Dogs; Haplorhini; HIV Protease Inhibitors; Humans; Hydrogen-Ion Concentration; Methanol; Pan troglodytes; Phosphates; Potassium Compounds; Rats; Sensitivity and Specificity; Urea | 1996 |
Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450.
Topics: Administration, Oral; Animals; Azepines; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Humans; Infusions, Intravenous; Mice; Microscopy, Electron; Solubility; Urea; Virus Replication | 1996 |
Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
Topics: Azepines; Binding Sites; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; Kinetics; Molecular Sequence Data; Mutagenesis, Insertional; Protein Conformation; Structure-Activity Relationship; Urea | 1997 |
Population dynamics studies of wild-type and drug-resistant mutant HIV in mixed infections.
Topics: Alkynes; Azepines; Benzoxazines; Cyclopropanes; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Microbial Sensitivity Tests; Oxazines; Population Dynamics; Reverse Transcriptase Inhibitors; Time Factors; Urea; Viral Plaque Assay | 1997 |
Molecular recognition of cyclic urea HIV-1 protease inhibitors.
Topics: Anti-HIV Agents; Azepines; HIV Protease; HIV Protease Inhibitors; HIV-1; Hydrogen Bonding; Molecular Conformation; Urea | 1998 |
Nonsymmetric P2/P2' cyclic urea HIV protease inhibitors. Structure-activity relationship, bioavailability, and resistance profile of monoindazole-substituted P2 analogues.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Azepines; Biological Availability; Cell Line; Chromatography, High Pressure Liquid; Dogs; Drug Design; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Indazoles; Mutation; Ritonavir; RNA, Viral; Structure-Activity Relationship; Transcription, Genetic; Urea | 1998 |
The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: modifications of the P1/P1' residues.
Topics: Antiviral Agents; Azepines; HIV; HIV Protease; HIV Protease Inhibitors; Indicators and Reagents; Kinetics; Molecular Structure; Structure-Activity Relationship; Urea | 1998 |
Utility of microcalorimetry in the characterization of the browning reaction.
Topics: Azepines; Calorimetry; Chromatography, High Pressure Liquid; HIV Protease Inhibitors; Hot Temperature; Lactose; Temperature; Urea | 1999 |
The influence of donor and reservoir additives on Caco-2 permeability and secretory transport of HIV protease inhibitors and other lipophilic compounds.
Topics: Acetamides; Albumins; Azepines; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Furans; HIV Protease Inhibitors; Humans; Indinavir; Intestinal Absorption; Nelfinavir; Ritonavir; Solvents; Structure-Activity Relationship; Sulfonamides; Urea | 2000 |
Catalytic carbonylation of functionalized diamines: application to the core structure of DMP 323 and DMP 450.
Topics: Azepines; Carbon Compounds, Inorganic; Catalysis; Diamines; HIV Protease Inhibitors; Molecular Structure; Tungsten; Urea | 2003 |
Inhibitor docking screened by the modified SAFE_p scoring function: application to cyclic urea HIV-1 PR inhibitors.
Topics: Algorithms; Amino Acids; Azepines; Binding Sites; Computer Simulation; HIV Protease; HIV Protease Inhibitors; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Structure; Protein Binding; Static Electricity; Thermodynamics; Urea | 2007 |
Synthesis and Biological Evaluation of 3,9-Dioxatetraasteranes as C
Topics: Azepines; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship; Urea; Urease | 2019 |