urea has been researched along with cyclosporine in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.23) | 18.7374 |
| 1990's | 31 (38.27) | 18.2507 |
| 2000's | 26 (32.10) | 29.6817 |
| 2010's | 21 (25.93) | 24.3611 |
| 2020's | 2 (2.47) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Avdeef, A; Tam, KY | 1 |
| Dhawan, IK; Hayes, K; Masri, MA; Pingle, A; Shakuntala, V | 1 |
| Bilo, HJ; Donker, AJ; Homan van der Heide, JJ; Sluiter, WJ; Tegzess, AM; Wilmink, JM | 1 |
| Daar, AS; Masri, MA; Naiem, M; Pingle, S | 1 |
| Anveden-Hertzberg, L; Sonnino, RE | 1 |
| Badalamenti, S; Como, G; Finazzi, S; Galmarini, D; Graziani, G; Lorenzano, E; Paone, G; Rimola, A; Sacchetta, AC; Salerno, F | 1 |
| Ezeamuzie, CI; Islam, SI; Khaleel, MH; Masuda, QN; Shaheen, FA; Sheikh, IA | 1 |
| Bernstein, K; Cattran, DC; Churchill, DN; Clark, WF; Greenwood, C; Lavoie, S; Morrin, PA; Ritchie, S | 1 |
| Braquet, P; Claude, JR; Dutertre-Catella, H; Martin, C; Massicot, F; Warnet, JM | 1 |
| Albanese, MC; Albertini, A; Baraldo, M; Furlanut, M; Pea, F; Puricelli, C | 1 |
| Duncan, S; Levy, GA; Liu, WT; Pang, H; Skorecki, K; Wong, PY | 1 |
| Lewin, E; Olgaard, K | 1 |
| Adams, KE; Brown, PA; Heys, SD; Whiting, PH | 1 |
| Jeffery, JJ; Penner, SB; Smyth, DD | 1 |
| Bilik, R; Hu, X; Superina, RA | 1 |
| Corey, HE; Greenstein, SM; Greifer, I; Spitzer, A; Tellis, V | 1 |
| Fernandes, MH; Pestana, M; Pinto-do-O, PC; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Dittmann, J; Kleinkauf, H; Lawen, A; Vaillant, F | 1 |
| Miotto, G; Pizzo, P; Rizzuto, R; Siliprandi, N; Venerando, R | 1 |
| Bryer, HP; Buchinsky, FJ; Epstein, S; Jee, WS; Ma, Y; Mann, GN; Romero, DF; Rucinski, B | 1 |
| Korn, A; Offermann, G | 1 |
| al Khader, A; al Sulaiman, M; Kishore, PN; Morais, C; Tariq, M | 1 |
| Hayashi, K; Nagamatsu, T; Oka, T; Suzuki, Y | 1 |
| Bencko, V; Farghali, H; Hynie, S; Kameníková, L | 1 |
| Aguilar, M; Andujar, M; Arrebola, F; del Moral, RG; García-Chicano, MJ; Gómez-Morales, M; Guillén, M; Masseroli, M; Nogales, FF; O'Valle, F; Olmo, A; Ramírez, C | 1 |
| Aziz, T; Campbell, C; Deiraniya, A; el-Gamel, A; Keevil, B; Martyszczuk, R; Rahman, A; Yonan, N | 1 |
| Brancato, T; De Vincenzo, A; Genovese, E; Migliaro, F; Pecoraro, C; Silvestre, C; Vajro, P | 1 |
| Brunton, C; Burns, A; Davenport, A; Fernando, ON; Fernando, RL; Moorhead, JF; Powis, SH; Psimenou, E; Sweny, P; Turakhia, G; Varghese, Z | 1 |
| Owunwanne, A; Shihab-Eldeen, A; Yacoub, T; Ziada, G | 1 |
| Kumar, KV; Naidu, MU; Prayag, A; Ratnakar, KS; Shifow, AA | 2 |
| Fernando, ON; Fernando, RL; Moorhead, JF; Powis, SH; Psimenou, E; Sweny, P; Turakhia, G; Varghese, Z | 1 |
| Alvárez-Cienfuegos, J; Girala, M; Gómez-Manero, N; Herrero, JI; Pardo, F; Prieto, J; Quiroga, J; Sangro, B | 1 |
| Bellotti, N; Campana, C; Dal Canton, A; Esposito, C; Fasoli, G; Fornoni, A; Gavazzi, A; Klersy, C; Rampino, T; Semeraro, L; Viganò, M | 1 |
| Bohdanecká, M; Chadimová, M; Dobesová, Z; Glagolicová, A; Kazdová, L; Kunes, J; Schück, O; Sedivý, J; Skibová, J; Stuchlík, M; Veselá, J | 1 |
| Angelini, A; Caforio, AL; Casarotto, D; Dalla Volta, S; Feltrin, G; Gambino, A; Marchini, F; Pompei, E; Testolin, L; Tona, F | 1 |
| Mális, F; Raffayová, H; Rovenský, J | 1 |
| Enomoto, N; Ikejima, K; Kolinsky, M; Li, X; Raleigh, JA; Thurman, RG; von Frankenberg, M; Yamashina, S; Zhong, Z | 1 |
| Canová, N; Farghali, H; Gaier, N; Kmonicková, E; Lincová, D; Masek, K; Strestíková, P | 1 |
| Abdelhadi, M; Ericzon, BG; Hultenby, K; Nordenström, J; Reinholt, FP; Sjöden, G | 1 |
| Al-Majed, A; Al-Rikabi, A; Daba, MH; Gado, A; Mansour, M | 1 |
| Dietz, A; Geiger, H; Gossmann, J; Kachel, HG; Kramer, W; Mondorf, U; Scheuermann, EH | 1 |
| Canová, N; Farghali, H; Gaier, N; Kameníková, L; Kmoníèková, E; Lincová, D; Vítek, L | 1 |
| Afify, EA; El-Mas, MM; Mohy El-Din, MM; Omar, AG; Sharabi, FM | 1 |
| Castro, I; Lima, EQ; Machado, MM; Massarollo, PC; Mies, S; Yu, L; Zanetta, DM | 1 |
| Czajkowski, K; Grymowicz, M; Malinowska-Polubiec, A; Romejko, E; Sieńko, J; Smolarczyk, R; Wójcicka-Bentyn, J | 1 |
| Honsova, E; Kocik, M; Kriz, J; Kudla, M; Mergental, H; Pantoflicek, T; Ryska, M; Saudek, F; Tcherentsova, K | 1 |
| Canová, N; Farghali, H; Kmonícková, E; Lincová, D; Vítek, L | 1 |
| Hiramoto, K; Inoue, M; Kashiwagi, A; Nishikawa, M; Sato, EF; Utsumi, K | 1 |
| Baikova, VN; Berezov, TT; Denisova, NA; Pletneva, TV | 1 |
| Clemente, R; de Gómez Dumm Nelva, T; Georgina, L; Gisela, C; Lausada, N | 1 |
| Budar-Fernandez, LF; Estrada-Oros, J; Martínez-Mier, G; Méndez-López, MT; Méndez-Machado, GF; Soto-González, JI; Viñas Dozal, JC | 1 |
| Câmara, NO; Cenedeze, MA; de Paula, CB; dos Reis, MA; Feitoza, CQ; Gonçalves, GM; Macusso, GD; Pacheco-Silva, A; Pinheiro, HS; Teixeira, Vde P | 1 |
| Coakley, JC; Earl, JW; McLachlan, AJ; Nath, CE; Shaw, PJ | 1 |
| Ateşşahin, A; Ceribaşi, AO; Yilmaz, S | 1 |
| Cologna, AJ; Lima, LV; Martins, AC; Reis, RB; Rodrigues, AA; Suaid, HJ; Tirapelli, LF; Tucci, S | 1 |
| Argani, H; Foroughimoghaddam, H; Ghorbanihaghjo, A; Mesgari, M; Rashtchizadeh, N; Safa, J | 1 |
| Ardalan, M; Azar, SA; Badrogli, N; Bahluli, A; Jahannavard, N; Khosroshahi, HT; Oskuii, R | 1 |
| Malyszko, J; Malyszko, JS; Mysliwiec, M | 1 |
| Attia, A; Chibbar, R; Elbarbry, F; Marfleet, T; Ragheb, A; Shoker, A | 1 |
| Alfano, L; Ciarcia, R; Damiano, S; Fiorito, F; Florio, S; Giordano, A; Granato, G; Iovane, V; Mastellone, V; Pagnini, F; Valenti, F | 1 |
| Abdollahifard, S; Bohlouli, A; Hashemi, B; Nezami, N; Zomorrodi, A | 1 |
| Abdel-latif, RG; El-Moselhy, MA; Khalifa, MA; Morsy, MA | 1 |
| Amiot, BP; Glorioso, J; Liu, H; Mao, S; Nyberg, SL; Rinaldo, P; Rodysil, B; Yu, Y | 1 |
| Balligand, JL; Bauersachs, J; Clerk, A; De Windt, L; Heymans, S; Hilfiker-Kleiner, D; Hirsch, E; Iaccarino, G; Knöll, R; Leite-Moreira, AF; Lourenço, AP; Mayr, M; Tarone, G; Thum, T; Tocchetti, CG | 1 |
| Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I | 1 |
| Ahmed, GO; Farag, MM; Kazem, AH; Shehata, RR | 1 |
| Augeul, L; Juillard, L; Laville, M; Lemoine, S; Ovize, M; Pillot, B; Rayberin, M; Rognant, N; Varennes, A | 1 |
| Alves, R; Carvalho, E; Nunes, S; Reis, F; Rocha-Pereira, P; Sereno, J; Teixeira, F; Vala, H | 1 |
| Annaert, P; Bachellier, P; Baze, A; Heyd, B; Oorts, M; Richert, L; Zacharias, T | 1 |
| Orchard, D; Yee, J | 1 |
| Elkamhawy, A; Hassan, AHE; Lee, J; Moon, B; Pae, AN; Park, BG; Park, HM; Park, JE; Ra, H; Roh, EJ | 1 |
| Borges, FT; Caires, A; Castino, B; Fernandes, GS; Fernandes, SM; Fonseca, CD; Leme, AM; Pessoa, EA; Schor, N; Vattimo, MF | 1 |
| Ain-Shoka, AA; Amin, NE; Aziz, MM; Eid, NI; Nada, AS | 1 |
| Abbasi, MM; Argani, H; Dastmalchi, S; Ghasemi, B; Ghazizadeh, T; Ghorbanihaghjo, A; Karimi, P; Raeisi, S; Seifi, M | 1 |
| Polley, S; Sau, S; Seal, S | 1 |
| Can, C; Çavuşoğlu, T; Çelenk, FG; Coşkunsever, D; Duman, S; Olukman, M; Sözmen, E; Ülker, S; Uyanikgil, Y | 1 |
| Domingues, MAC; Módolo, NSP; Oliveira, ACC; Schwingel, PA | 1 |
| André, C; Bennis, Y; Bodeau, S; Choukroun, G; Kamel, S; Lemaire-Hurtel, AS; Liabeuf, S; Masmoudi, K | 1 |
| Ghafil, FA; Hadi, NR; Kadhim, SAA; Majeed, S; Qassam, H | 1 |
4 review(s) available for urea and cyclosporine
| Article | Year |
|---|---|
Treatment with cyclosporin in patients with psoriatic arthritis: results of clinical assessment.
Topics: Adult; Arthritis, Psoriatic; Cholesterol; Creatinine; Cyclosporine; Dermatologic Agents; Drug Monitoring; Humans; Male; Middle Aged; Urea | 2000 |
Free radical theory of apoptosis and metamorphosis.
Topics: Animals; Apoptosis; Calcium; Carnitine; Catalase; Cell Survival; Cyclosporine; DNA; Enzyme Inhibitors; Free Radicals; Humans; Metamorphosis, Biological; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Oxygen; Ranidae; Reactive Oxygen Species; Time Factors; Urea | 2004 |
Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.
Topics: Cell Survival; Cyclosporine; Drugs, Investigational; Heart Failure; Humans; Hypertrophy, Left Ventricular; Myocardial Contraction; Myocytes, Cardiac; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Translational Research, Biomedical; Urea; Ventricular Remodeling | 2014 |
Monitoring recommendations for oral azathioprine, methotrexate and cyclosporin in a paediatric dermatology clinic and literature review.
Topics: Administration, Oral; Adolescent; Azathioprine; Blood Cell Count; Child; Child, Preschool; Creatinine; Cyclosporine; Drug Monitoring; Electrolytes; Female; Humans; Immunoglobulin E; Immunosuppressive Agents; Liver Function Tests; Male; Methotrexate; Methyltransferases; Retrospective Studies; Skin Diseases; Urea | 2018 |
8 trial(s) available for urea and cyclosporine
| Article | Year |
|---|---|
The effects of dietary supplementation with fish oil on renal function and the course of early postoperative rejection episodes in cyclosporine-treated renal transplant recipients.
Topics: Creatinine; Cyclosporine; Diet; Double-Blind Method; Female; Fish Oils; Graft Rejection; Histocompatibility; Humans; Immunosuppression Therapy; Kidney; Kidney Transplantation; Male; Prospective Studies; Urea | 1992 |
Renal effects of dietary supplementation with fish oil in cyclosporine-treated liver transplant recipients.
Topics: Adolescent; Adult; Cyclosporine; Dietary Fats, Unsaturated; Double-Blind Method; Fatty Acids; Female; Fish Oils; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Placebos; Prospective Studies; Renal Plasma Flow, Effective; Thromboxane B2; Urea | 1995 |
The impact of long-term cyclosporin-A therapy on hematological and biochemical profile in renal transplant patients.
Topics: Adult; Azathioprine; Biomarkers; Cyclosporine; Drug Therapy, Combination; Female; Fluorescence Polarization; Hematocrit; Hemoglobins; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Prednisolone; Treatment Outcome; Urea; Uric Acid | 1995 |
A controlled trial of cyclosporine in patients with progressive membranous nephropathy. Canadian Glomerulonephritis Study Group.
Topics: Adult; Aged; Creatinine; Cyclosporine; Female; Follow-Up Studies; Glomerulonephritis, Membranous; Humans; Male; Middle Aged; Prospective Studies; Proteinuria; Risk Factors; Urea | 1995 |
Safety and tolerability of CyA microemulsion formulation (Sandimmun Neoral) in stable renal transplant patients after 24 months of treatment. German Neoral Study Group.
Topics: Administration, Oral; Creatinine; Cyclosporine; Double-Blind Method; Emulsions; Gingiva; Humans; Hyperplasia; Immunosuppressive Agents; Kidney Transplantation; Time Factors; Urea | 1996 |
Treatment with cyclosporin in patients with psoriatic arthritis: results of clinical assessment.
Topics: Adult; Arthritis, Psoriatic; Cholesterol; Creatinine; Cyclosporine; Dermatologic Agents; Drug Monitoring; Humans; Male; Middle Aged; Urea | 2000 |
A randomized prospective double-blind placebo-controlled study of gallopamil, calcium antagonist of the verapamil type, in stable cyclosporine-treated renal transplant recipients.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Creatinine; Cyclosporine; Double-Blind Method; Gallopamil; Humans; Immunosuppressive Agents; Kidney Transplantation; Placebos; Prospective Studies; Urea; Uric Acid; Verapamil | 2002 |
Amphotericin B dose optimization in children with malignant diseases.
Topics: Adolescent; Amphotericin B; Antifungal Agents; Body Weight; Child; Child, Preschool; Computer Simulation; Creatinine; Cyclosporine; Deoxycholic Acid; Drug Combinations; gamma-Glutamyltransferase; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Microbial Sensitivity Tests; Models, Biological; Mycoses; Neoplasms; Risk Factors; Urea | 2007 |
70 other study(ies) available for urea and cyclosporine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Safe use of acyclovir (Zovirax) in renal transplant patients on cyclosporine A therapy: case reports.
Topics: Acyclovir; Adult; Chickenpox; Child; Creatinine; Cyclosporine; Drug Interactions; Herpes Zoster; Humans; Kidney Transplantation; Urea | 1992 |
Cyclosporine A versus cyclosporine G: a comparative study of survival, hepatotoxicity, nephrotoxicity, and splenic atrophy in BALB/c mice.
Topics: Animals; Behavior, Animal; Cyclosporine; Cyclosporins; Kidney; Liver; Mice; Mice, Inbred BALB C; Spleen; Urea | 1988 |
Impaired survival and growth in immunosuppressed young rats with lethal short gut syndrome and a small bowel transplant: an effect of cyclosporine.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cecum; Creatinine; Cyclosporine; Growth; Immunocompromised Host; Intestine, Small; Jejunum; Laparotomy; Male; Rats; Rats, Inbred BN; Rats, Inbred Lew; Serum Albumin; Short Bowel Syndrome; Survival Rate; Transplantation, Homologous; Transplantation, Isogeneic; Triglycerides; Urea | 1995 |
Protection against cyclosporin-induced nephrotoxicity: 1. Effect of a PAF antagonist, BN50726.
Topics: Animals; Azepines; Creatinine; Cyclosporine; Drug Interactions; Glutathione; Kidney Cortex; Kidney Diseases; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thienopyridines; Urea | 1994 |
Effect of fluctuations of blood cyclosporine concentrations on renal function.
Topics: Creatinine; Cyclosporine; Follow-Up Studies; Heart Transplantation; Humans; Kidney; Predictive Value of Tests; Time Factors; Urea | 1994 |
Isolation and identification of two cyclosporine aldehydic metabolites from the bile of a liver transplant recipient during an acute nephrotoxic episode.
Topics: Animals; Aspartate Aminotransferases; Bile; Cell Line; Creatinine; Cyclosporine; Cyclosporins; Humans; Kidney Function Tests; Liver Transplantation; Male; Mice; Middle Aged; Molecular Structure; Rats; Swine; Urea | 1994 |
The in vivo effect of a new, in vitro, extremely potent vitamin D3 analog KH1060 on the suppression of renal allograft rejection in the rat.
Topics: Animals; Calcitriol; Calcium; Cholecalciferol; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Graft Rejection; Graft Survival; Immunosuppressive Agents; In Vitro Techniques; Injections, Intraperitoneal; Kidney; Kidney Transplantation; Rats; Rats, Inbred Lew; Transplantation, Homologous; Urea | 1994 |
Alleviation of experimental cyclosporin A nephrotoxicity by low dose aspirin in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Creatinine; Cyclosporine; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Thromboxane A2; Urea | 1993 |
Cyclosporine-induced nephrotoxicity in the rat. The effect of alpha 1-adrenoceptor blockade with prazosin.
Topics: Animals; Body Weight; Cyclosporine; Kidney; Kidney Transplantation; Male; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sodium; Sympathetic Nervous System; Urea | 1993 |
Long-term effect of cyclosporine on renal function in children after liver transplantation.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Creatinine; Cyclosporine; Humans; Infant; Kidney; Kidney Function Tests; Liver Transplantation; Muromonab-CD3; Retrospective Studies; Urea | 1993 |
The fractional excretion of urea: a new diagnostic test for acute renal allograft rejection.
Topics: Acute Disease; Adolescent; Adult; Bacterial Infections; Child; Child, Preschool; Cyclosporine; Diagnosis, Differential; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Sodium; Transplantation, Homologous; Urea; Virus Diseases | 1993 |
Assessment of renal dopaminergic system activity during cyclosporine A administration in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Catechol O-Methyltransferase; Creatinine; Cyclosporine; Dopamine; Homovanillic Acid; In Vitro Techniques; Injections, Subcutaneous; Kidney Cortex; Kidney Tubules; Levodopa; Male; Monoamine Oxidase; Potassium; Rats; Rats, Wistar; Sodium; Urea | 1995 |
Reversible denaturation of cyclosporin synthetase by urea.
Topics: Cyclosporine; Fungi; Multienzyme Complexes; Peptide Synthases; Peptides, Cyclic; Piperazines; Protein Conformation; Protein Denaturation; Protein Folding; Urea | 1996 |
Mitochondrial alterations induced by aspirin in rat hepatocytes expressing mitochondrially targeted green fluorescent protein (mtGFP).
Topics: Animals; Aspirin; Cell Survival; Cells, Cultured; Cyclosporine; Fluorescent Dyes; Green Fluorescent Proteins; Luminescent Proteins; Male; Mitochondria, Liver; Rats; Rats, Wistar; Rhodamine 123; Rhodamines; Transfection; Urea | 1996 |
T lymphocytes play a critical role in the development of cyclosporin A-induced osteopenia.
Topics: Animals; Blood Glucose; Bone and Bones; Bone Diseases, Metabolic; Calcitriol; Calcium; Creatinine; Cyclosporine; Immunosuppressive Agents; Male; Osteocalcin; Parathyroid Hormone; Rats; Rats, Nude; Rats, Sprague-Dawley; T-Lymphocytes; Urea | 1996 |
Quinacrine attenuates cyclosporine-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Cyclosporine; Electrolytes; Free Radicals; Glutathione; Kidney; Kidney Diseases; Male; Malondialdehyde; Quinacrine; Rats; Rats, Wistar; Urea; Vitamin E | 1996 |
Modulation of anti-glomerular basement membrane nephritis in rats by ONO-1301, a non-prostanoid prostaglandin I2 mimetic compound with inhibitory activity against thromboxane A2 synthase.
Topics: Animals; Basement Membrane; Cells, Cultured; Cholesterol; Complement C3; Cyclic AMP; Cyclosporine; Endothelium, Vascular; Glomerulonephritis; Humans; Immunoglobulin G; Immunosuppressive Agents; Integrin alpha4beta1; Integrin beta1; Integrins; Kidney Glomerulus; Male; Proteinuria; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lymphocyte Homing; Thromboxane-A Synthase; Tumor Necrosis Factor-alpha; Umbilical Veins; Urea; Vascular Cell Adhesion Molecule-1 | 1997 |
Response of immobilized hepatocytes in a perfusion system to anoxia/reoxygenation: effect of cyclosporine A pretreatment.
Topics: Animals; Cell Hypoxia; Cell Membrane; Cells, Cultured; Cells, Immobilized; Cyclosporine; Immunosuppressive Agents; L-Lactate Dehydrogenase; Liver; Male; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Urea | 1996 |
Chronic cyclosporin A nephrotoxicity, P-glycoprotein overexpression, and relationships with intrarenal angiotensin II deposits.
Topics: Angiotensin II; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Chronic Disease; Creatinine; Cyclosporine; Gene Expression Regulation; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Urea | 1997 |
Clinical impact of Neoral in heart transplantation.
Topics: Administration, Oral; Adolescent; Adult; Aged; Azathioprine; Creatinine; Cyclosporine; Drug Therapy, Combination; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Function Tests; Middle Aged; Prednisolone; Urea | 1998 |
Monitoring of renal function in children before and after liver transplantation.
Topics: Analysis of Variance; Blood Pressure; Child, Preschool; Creatinine; Cyclosporine; Electrolytes; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Function Tests; Liver Transplantation; Longitudinal Studies; Male; Monitoring, Physiologic; Prednisone; Time Factors; Urea | 1998 |
Oxidizability of low-density lipoproteins from Neoral and tacrolimus-treated renal transplant patients.
Topics: Adrenal Cortex Hormones; Antioxidants; Azathioprine; Cholesterol; Creatine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Kinetics; Lipoproteins, LDL; Male; Middle Aged; Tacrolimus; Triglycerides; Urea | 1998 |
The use of radiopharmaceuticals as an effective toxicologic technique for studying nephrotoxicity of drugs: cyclosporine-A.
Topics: Animals; Autoradiography; Creatinine; Cyclosporine; Kidney Diseases; Rabbits; Radioisotope Renography; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Technetium Tc 99m Mertiatide; Urea | 1998 |
Melatonin: an antioxidant protects against cyclosporine-induced nephrotoxicity.
Topics: Animals; Antioxidants; Calcinosis; Creatinine; Cyclosporine; Kidney Diseases; Lithium; Male; Malondialdehyde; Melatonin; Nephrons; Rats; Rats, Wistar; Urea | 1999 |
Calcineurin inhibitors enhance low-density lipoprotein oxidation in transplant patients.
Topics: Adult; Ascorbic Acid; Calcineurin Inhibitors; Cholesterol; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Tacrolimus; Time Factors; Triglycerides; Urea; Vitamin E | 1999 |
Conversion of liver transplant recipients on cyclosporine with renal impairment to mycophenolate mofetil.
Topics: Aged; Azathioprine; Biopsy; Blood Pressure; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocorticoids; Graft Rejection; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Lipids; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Prednisone; Renal Insufficiency; Retrospective Studies; Tacrolimus; Treatment Outcome; Urea | 1999 |
Risk factors for chronic renal dysfunction in cardiac allograft recipients.
Topics: Adolescent; Adult; Aged; Creatinine; Cyclosporine; Female; Heart Transplantation; Humans; Hyperlipidemias; Immunosuppressive Agents; Kidney Failure, Chronic; Male; Middle Aged; Retrospective Studies; Risk Factors; Urea | 2000 |
Nephrotoxicity of cyclosporin A in hereditary hypertriglyceridemic rats.
Topics: Animals; Creatine; Cyclosporine; Fatty Acids, Omega-3; Hypertriglyceridemia; Immunosuppressive Agents; Kidney; Male; Osmolar Concentration; Potassium; Proteinuria; Rats; Rats, Mutant Strains; Rats, Wistar; Sodium; Triglycerides; Urea; Vitamin E | 1999 |
Sulfinpyrazone reduces cyclosporine levels: a new drug interaction in heart transplant recipients.
Topics: Allopurinol; Creatinine; Cyclosporine; Drug Interactions; Female; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Risk Factors; Sulfinpyrazone; Urea; Uric Acid; Uricosuric Agents | 2000 |
Effect of pentoxifylline on cyclosporine-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Male; Pentoxifylline; Rats; Rats, Wistar; Urea; Vasodilator Agents | 2000 |
Cyclosporin A causes a hypermetabolic state and hypoxia in the liver: prevention by dietary glycine.
Topics: Animals; Body Weight; Calcium; Chemical and Drug Induced Liver Injury; Cyclosporine; Dietary Supplements; Dinoprostone; Eating; Glycine; Hypoxia; Immunosuppressive Agents; Kupffer Cells; Liver Diseases; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Urea | 2001 |
Inhibition of endotoxemia-induced nitric oxide synthase expression by cyclosporin A enhances hepatocyte injury in rats: amelioration by NO donors.
Topics: Alanine Transaminase; Animals; Cell Separation; Cells, Immobilized; Chromatography, Agarose; Cold Temperature; Culture Media; Cyclosporine; Endotoxemia; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepatocytes; Immunosuppressive Agents; Lipid Peroxidation; Male; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Urea | 2002 |
Structural skeletal impairment induced by immunosuppressive therapy in rats: cyclosporine A vs tacrolimus.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone and Bones; Bone Density; Calcium; Creatinine; Cyclosporine; Epiphyses; Growth Plate; Immunosuppressive Agents; Male; Organ Size; Parathyroid Hormone; Phosphates; Rats; Rats, Sprague-Dawley; Tacrolimus; Urea | 2002 |
Protective effect of L-arginine against nephrotoxicity induced by cyclosporine in normal rats.
Topics: Animals; Arginine; Creatinine; Cyclosporine; Enzyme Inhibitors; Glutathione Peroxidase; Guanidines; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Tubules; Male; Nephritis, Interstitial; Nitric Oxide Synthase; Rats; Rats, Inbred Strains; Urea | 2002 |
Urea synthesis and cyclosporin a biotransformation in a laboratory scale hepatocyte bioreactor model.
Topics: Animals; Bioreactors; Biotransformation; Cyclosporine; Hepatocytes; Male; Models, Biological; Rats; Rats, Wistar; Urea | 2002 |
Testosterone depletion contributes to cyclosporine-induced chronic impairment of acetylcholine renovascular relaxations.
Topics: Acetylcholine; Animals; Creatinine; Cyclosporine; Drug Interactions; Endothelium, Vascular; Female; Kidney; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Orchiectomy; Perfusion; Phenylephrine; Rats; Rats, Inbred Strains; Rats, Wistar; Renal Artery; Testosterone; Urea | 2003 |
Risk factors for development of acute renal failure after liver transplantation.
Topics: Acute Kidney Injury; Adult; Bilirubin; Biomarkers; Blood Transfusion; Brazil; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Hypotension; Immunosuppressive Agents; Kidney; Liver Failure; Liver Transplantation; Male; Middle Aged; Oliguria; Postoperative Complications; Potassium; Renal Dialysis; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Failure; Urea | 2003 |
Renal function and lipid metabolism in pregnant renal transplant recipients.
Topics: Acidosis; Adult; Azathioprine; Chlorides; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Lipids; Phospholipids; Prednisone; Pregnancy; Pregnancy Complications; Proteinuria; Triglycerides; Urea; Uric Acid | 2004 |
Gemcitabine does not prevent acute rejection of the transplanted liver in rats.
Topics: Acute Disease; Animals; Creatinine; Cyclosporine; Deoxycytidine; Gemcitabine; Graft Rejection; Immunosuppressive Agents; Liver; Liver Transplantation; Male; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Treatment Failure; Urea | 2005 |
Evaluation of a flat membrane hepatocyte bioreactor for pharmacotoxicological applications: evidence that inhibition of spontaneously produced nitric oxide improves cell functionality.
Topics: Analysis of Variance; Animal Use Alternatives; Animals; Bioreactors; Biotransformation; Chromatography, High Pressure Liquid; Cyclosporine; Evaluation Studies as Topic; Hepatocytes; Membranes; Nitric Oxide; Rats; Time Factors; Toxicity Tests; Urea | 2004 |
Kinetic characteristics of biochemical parameters during consupren therapy after allogenic transplantation of the kidney.
Topics: Adolescent; Adult; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Kinetics; Male; Middle Aged; Transplantation, Homologous; Urea | 2004 |
Effect of different immunosuppressive therapies on the lipid pattern in kidney-transplanted rats.
Topics: Animals; Cholesterol; Creatinine; Cyclosporine; Erythrocyte Membrane; Hyperlipidemias; Immunosuppressive Agents; Kidney; Kidney Transplantation; Lipid Metabolism; Lipids; Male; Membrane Lipids; Methylprednisolone; Microsomes, Liver; Rats; Rats, Wistar; Sirolimus; Testis; Triglycerides; Urea | 2005 |
Conversion from calcineurin inhibitor to sirolimus for renal function deterioration in kidney allograft recipients.
Topics: Adult; Calcineurin Inhibitors; Calcium; Creatinine; Cyclosporine; Enzyme Inhibitors; Female; Graft Rejection; Graft Survival; Hemoglobins; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Monitoring, Physiologic; Potassium; Retrospective Studies; Sirolimus; Transplantation, Homologous; Treatment Outcome; Urea | 2006 |
Heme oxygenase 1 and renal ischemia and reperfusion injury: the impact of immunosuppressive drug.
Topics: Animals; Creatinine; Cyclosporine; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Immunosuppressive Agents; Kidney; Male; Mice; Mice, Inbred C57BL; Protoporphyrins; Reperfusion Injury; Urea | 2006 |
Lycopene, a carotenoid, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Calcium; Carotenoids; Catalase; Creatinine; Cyclosporine; Glutathione; Glutathione Peroxidase; Immunosuppressive Agents; Lycopene; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium; Thiobarbituric Acid Reactive Substances; Urea | 2007 |
Cyclosporine action on kidneys of rats submitted to normothermic ischaemia and reperfusion.
Topics: Animals; Biomarkers; Creatinine; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Nephrectomy; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Urea | 2008 |
Effect of isoproterenol on cyclosporine-induced nephrotoxicity in rat.
Topics: Animals; Antioxidants; Creatinine; Cyclosporine; Isoproterenol; Kidney; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Urea | 2008 |
Safety of low-dose cyclosporine therapy before transplantation in kidney allograft recipients.
Topics: Adult; Case-Control Studies; Creatinine; Cyclosporine; Diuresis; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Male; Postoperative Period; Preoperative Care; Safety; Transplantation, Homologous; Urea | 2009 |
A possible role of hepcidin in the pathogenesis of anemia among kidney allograft recipients.
Topics: Analysis of Variance; Anemia; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cholesterol; Creatinine; Cross-Sectional Studies; Cyclosporine; Drug Therapy, Combination; Erythrocyte Count; Glomerular Filtration Rate; Hematocrit; Hepcidins; Humans; Immunosuppressive Agents; Kidney Transplantation; Postoperative Complications; Prednisone; Regression Analysis; Tacrolimus; Transplantation, Homologous; Triglycerides; Urea | 2009 |
Cyclosporine-induced changes in drug metabolizing enzymes in hyperlipemic rabbit kidneys could explain its toxicity.
Topics: Animals; Antioxidants; Cholesterol, Dietary; Creatinine; Cyclosporine; Cytochrome P-450 CYP2E1; Female; Glutathione; Hyperlipidemias; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Lipids; Oxidative Stress; Rabbits; Reactive Oxygen Species; Urea | 2010 |
Hydrocortisone attenuates cyclosporin A-induced nephrotoxicity in rats.
Topics: Animals; Apoptosis; Blood Pressure; Catalase; Cholesterol; Creatinine; Cyclosporine; Glutathione Peroxidase; Hydrocortisone; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Male; Rats; Rats, Wistar; Superoxide Dismutase; Urea | 2012 |
Effect of lymph leakage on renal allograft outcome from living donors.
Topics: Adult; Case-Control Studies; Creatinine; Cyclosporine; Female; Humans; Kidney Transplantation; Length of Stay; Living Donors; Lymph; Male; Middle Aged; Prognosis; Transplantation, Homologous; Urea | 2012 |
Sildenafil protects against nitric oxide deficiency-related nephrotoxicity in cyclosporine A treated rats.
Topics: Albuminuria; Animals; Catalase; Creatinine; Cyclosporine; Glutathione; Immunosuppressive Agents; Kidney Diseases; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Phosphodiesterase 5 Inhibitors; Piperazines; Protective Agents; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Urea | 2013 |
Cold storage of rat hepatocyte spheroids.
Topics: Adenosine; Albumins; Allopurinol; Ammonia; Animals; Cell Survival; Cold Temperature; Culture Media, Serum-Free; Cyclosporine; Cytochrome P-450 Enzyme System; Deferoxamine; Glutathione; Hepatocytes; Insulin; Organ Preservation Solutions; Raffinose; Rats; Spheroids, Cellular; Time Factors; Urea | 2014 |
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid | 2014 |
Thymoquinone improves the kidney and liver changes induced by chronic cyclosporine A treatment and acute renal ischaemia/reperfusion in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Benzoquinones; Creatinine; Cyclosporine; Glutathione; Kidney; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Reperfusion Injury; Superoxide Dismutase; Urea | 2015 |
Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition.
Topics: Animals; Apoptosis; Biomarkers; Creatinine; Cyclosporine; Cytoprotection; Immunosuppressive Agents; Ischemic Postconditioning; Kidney; Kidney Transplantation; Male; Mice, Inbred BALB C; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Animal; Nephrectomy; Oxidative Phosphorylation; Reperfusion Injury; Time Factors; Urea | 2015 |
Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat.
Topics: Acute-Phase Proteins; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cell Adhesion Molecules; Cholesterol; Connective Tissue Growth Factor; Creatinine; Cyclosporine; Glomerular Filtration Rate; Heart Rate; Kidney; Kidney Diseases; Lipid Peroxidation; Lipocalin-2; Lipocalins; Male; NF-kappa B; Proto-Oncogene Proteins; Rats; Rats, Wistar; Sirolimus; TOR Serine-Threonine Kinases; Triglycerides; Urea | 2015 |
Drug-induced cholestasis risk assessment in sandwich-cultured human hepatocytes.
Topics: Bile Acids and Salts; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholestasis; Cyclosporine; Hepatocytes; Humans; Risk Assessment; Urea | 2016 |
Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Drug Discovery; Hippocampus; Immunosuppressive Agents; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Molecular Docking Simulation; Neurons; Piperazines; Protein Conformation; Urea | 2017 |
Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats.
Topics: Acute Kidney Injury; Animals; Bosentan; Creatinine; Cyclosporine; Endothelin A Receptor Antagonists; Hemodynamics; Immunoblotting; Immunohistochemistry; Immunosuppressive Agents; Kidney; Male; Oxidative Stress; Protective Agents; Pyrimidines; Rats, Inbred SHR; Rats, Wistar; Reproducibility of Results; Sulfonamides; Treatment Outcome; Urea | 2017 |
Possible protective effect of the algae spirulina against nephrotoxicity induced by cyclosporine A and/or gamma radiation in rats.
Topics: Animals; Creatinine; Cyclosporine; Gamma Rays; Glutathione; Immunosuppressive Agents; Kidney; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Spirulina; Thiobarbituric Acid Reactive Substances; Urea | 2018 |
Oxidative stress-induced renal telomere shortening as a mechanism of cyclosporine-induced nephrotoxicity.
Topics: Aging; Animals; Biomarkers; Body Weight; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Male; Oxidative Stress; Rats, Wistar; Telomerase; Telomere Shortening; Urea | 2018 |
A staphylococcal cyclophilin carries a single domain and unfolds via the formation of an intermediate that preserves cyclosporin A binding activity.
Topics: Bacterial Proteins; Cyclophilins; Cyclosporine; Protein Binding; Protein Domains; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteolysis; Staphylococcus aureus; Urea | 2019 |
Urotensin receptor antagonist palosuran attenuates cyclosporine-a-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Models, Animal; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Urea; Urotensins | 2019 |
Effects of cyclosporine on ischemia-reperfusion injuries in rat kidneys. An experimental model.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion Injury; Sodium; Urea | 2019 |
Potential interactions between uraemic toxins and drugs: an application in kidney transplant recipients treated with calcineurin inhibitors.
Topics: Aged; Calcineurin Inhibitors; Cross-Sectional Studies; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Tacrolimus; Transplant Recipients; Urea; Uremic Toxins | 2022 |
Nephroprotective effects of Candesartan Cilexetil against Cyclosporine A-induced nephrotoxicity in a rat model.
Topics: Animals; Catalase; Creatinine; Cyclosporine; Immunosuppressive Agents; Interleukin-2; Kidney; Kidney Diseases; Oxidative Stress; Rats; Rats, Wistar; Renal Insufficiency; Superoxide Dismutase; Urea | 2022 |