urea has been researched along with benzofurans in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.25) | 18.7374 |
| 1990's | 11 (34.38) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 6 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, RM; Beerman, TA; Meegan, RL; Woynarowski, JM; Zsido, TJ | 1 |
| Gibson, NW; Lee, CS | 1 |
| Boine, L | 1 |
| Dawber, RP | 1 |
| Adams, JL; Breton, JJ; Chabot-Fletcher, MC; Griswold, DE; Hay, DW; Kagey-Sobotka, A; Marshall, LA; Sarau, HM; Underwood, DC; Winkler, JD | 1 |
| Ames, MM; Reid, JM; Walker, DL | 1 |
| Gibson, NW; Lee, CS; Pfeifer, GP | 1 |
| Angioli, R; Averette, H; Hightower, RD; Nguyen, H; Perras, J; Sevin, BU; Untch, M | 1 |
| Adams, JL; Breton, JJ; Brian, WR; Chabot-Fletcher, M; Garigipati, RS; Garver, E; Griswold, DE; Newton, JF; Schmidt, SJ; Sorenson, M; Tyrrell, KA; Tzimas, M; Webb, EF; Yodis, LA | 1 |
| Kearney, AS; McLoughlin, M; Palepu, NR | 1 |
| Von Hoff, DD | 1 |
| Cerna, C; Gomez, L; Hidalgo, M; Izbicka, E; Rowinsky, EK; Von Hoff, DD; Weitman, SD | 1 |
| Chung, KF; Hisada, T; Nasuhara, Y; Salmon, M | 1 |
| Johnson, CM; Posobiec, LM; Rendemonti, JE; Rumberger, DF; Solomon, HM; Wier, PJ | 1 |
| Arnett, B; Napier, C; Trevino, AV; Woynarowski, JM | 1 |
| O'Donnell, EK; Schultz, BD; Sedlacek, RL; Singh, AK | 1 |
| Koba, M; Konopa, J; Skladanowski, A | 1 |
| Asikainen, A; Kilpinen, P; Mueller, C; Ruokojärvi, P; Ruuskanen, J; Tuppurainen, K; Yli-Keturi, N | 1 |
| Kilpinen, P; Mueller, C; Ruokojärvi, P; Ruuskanen, J; Tuppurainen, K | 1 |
| Horiuchi, S; Miyazaki, A | 1 |
| Woynarowski, JM | 1 |
| Babiuk, RP; Clugston, R; Greer, JJ; Mey, J; Zhang, W | 1 |
| Beerman, T; Cao, PR; McHugh, MM; Melendy, T | 1 |
| Bai, S; Goodrich, DW | 1 |
| Kaldis, SP; Palladas, A; Sakellaropoulos, GP; Skodras, G | 1 |
| Ginsburg, H; Krugliak, M; Woynarowski, JM | 1 |
| Anderson, JT; Ayral-Kaloustian, S; Brooijmans, N; Das, S; Hollander, I; Lucas, J; Mallon, R; Nguyen, T; Venkatesan, AM; Yu, K; Zhang, N | 1 |
| Aiyar, N; Burns-Kurtis, CL; Davenport, EA; Erhardt, JA; Kallal, LA; Marino, JP; Morrow, DM; Senadhi, S; Thalji, RK | 1 |
| Kantevari, S; Sridhar, B; Sriram, D; Yempala, T; Yogeeswari, P | 1 |
| Chen, T; Hu, YJ; Li, XD; Qi, ZF; Yan, M | 1 |
| Li, X; Qi, Z; Ren, J; Xu, Z; Yan, M; Yang, J | 1 |
| Basile, L; Gazioglu, I; Ginex, T; Guccione, S; Kucukislamoglu, M; Kurt, BZ; Sonmez, F | 1 |
3 review(s) available for urea and benzofurans
| Article | Year |
|---|---|
Promising new agents for treatment of patients with colorectal cancer.
Topics: Adenoviridae; Antineoplastic Agents; Benzofurans; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Duocarmycins; Enzyme Inhibitors; Humans; Indoles; Phenylurea Compounds; Sesquiterpenes; Thymidylate Synthase; Tumor Cells, Cultured; Urea | 1998 |
[ACAT inhibitors].
Topics: Anilides; Animals; Arteriosclerosis; Benzofurans; Cholesterol Esters; Cyclohexanes; Dioxanes; Endothelium, Vascular; Humans; Hyperlipidemias; Imidazoles; Intestine, Small; Liver; Organ Specificity; Phenylurea Compounds; Sterol O-Acyltransferase; Urea | 2001 |
Targeting critical regions in genomic DNA with AT-specific anticancer drugs.
Topics: Antineoplastic Agents; Base Sequence; Benzofurans; Binding Sites; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA Damage; DNA, Neoplasm; Drug Design; Duocarmycins; Genome, Human; Humans; Indoles; Nitrogen Mustard Compounds; Tandem Repeat Sequences; Tumor Cells, Cultured; Urea | 2002 |
1 trial(s) available for urea and benzofurans
| Article | Year |
|---|---|
[Benziodarone in hyperuricemia due to renal insufficiency].
Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Benzofurans; Clinical Trials as Topic; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Metabolic Clearance Rate; Middle Aged; Urea; Uric Acid | 1973 |
28 other study(ies) available for urea and benzofurans
| Article | Year |
|---|---|
Resistance of CHO cells expressing P-glycoprotein to cyclopropylpyrroloindole (CPI) alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzofurans; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Drug Resistance; Duocarmycins; Indoles; Leucomycins; Membrane Glycoproteins; Urea | 1992 |
DNA damage and differential cytotoxicity produced in human carcinoma cells by CC-1065 analogues, U-73,975 and U-77,779.
Topics: Antibiotics, Antineoplastic; Benzofurans; Carcinoma; Cell Death; Colonic Neoplasms; Cross-Linking Reagents; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Dose-Response Relationship, Drug; Duocarmycins; Humans; Indoles; Leucomycins; Lung Neoplasms; Plasmids; Tumor Cells, Cultured; Urea | 1991 |
Oral trisoralen therapy in vitiligo.
Topics: Administration, Oral; Adult; Benzofurans; Blood Cell Count; Female; Humans; Liver Function Tests; Male; Middle Aged; Pigmentation; Sunlight; Ultraviolet Therapy; Urea; Vitiligo | 1970 |
Pharmacological characterization of SB 202235, a potent and selective 5-lipoxygenase inhibitor: effects in models of allergic asthma.
Topics: Animals; Antigens; Asthma; Benzofurans; Bronchoconstriction; Disease Models, Animal; Eosinophils; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Trachea; Urea | 1995 |
Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Cyclohexenes; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Urea | 1994 |
Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction.
Topics: Alkylating Agents; Base Sequence; Benzofurans; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA; Duocarmycins; Genes, p53; Humans; Indoles; Molecular Sequence Data; Phosphoglycerate Kinase; Polymerase Chain Reaction; Tumor Cells, Cultured; Urea | 1994 |
In vitro evaluation of the novel chemotherapeutic agents U-73,975, U-77,779, and U-80,244 in gynecologic cancer cell lines.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Benzofurans; Cisplatin; Cyclohexanecarboxylic Acids; Cyclohexenes; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Duocarmycins; Endometrial Neoplasms; Female; Humans; In Vitro Techniques; Indoles; Ovarian Neoplasms; Tumor Cells, Cultured; Urea; Uterine Cervical Neoplasms | 1993 |
Bicyclic N-hydroxyurea inhibitors of 5-lipoxygenase: pharmacodynamic, pharmacokinetic, and in vitro metabolic studies characterizing N-hydroxy-N-(2,3-dihydro-6-(phenylmethoxy)-3-benzofuranyl)urea.
Topics: Animals; Benzofurans; Chromatography, High Pressure Liquid; Dogs; Humans; Lipoxygenase Inhibitors; Macaca fascicularis; Magnetic Resonance Spectroscopy; Male; Mice; Stereoisomerism; Urea | 1996 |
Aqueous stability of SB 210661: kinetics and primary degradation mechanisms of an N-hydroxyurea-containing 5-lipoxygenase inhibitor.
Topics: Benzofurans; Drug Stability; Hydrogen-Ion Concentration; Hydroxyurea; Kinetics; Lipoxygenase Inhibitors; Urea; Water | 1998 |
Comparative activity of the cyclopropylpyrroloindole compounds adozelesin, bizelesin and carzelesin in a human tumor colony-forming assay.
Topics: Antineoplastic Agents; Benzofurans; Cyclohexanecarboxylic Acids; Cyclohexenes; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Tumor Cells, Cultured; Urea | 1999 |
Cysteinyl-leukotrienes partly mediate eotaxin-induced bronchial hyperresponsiveness and eosinophilia in IL-5 transgenic mice.
Topics: Acetylcholine; Airway Resistance; Animals; Benzofurans; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Chromones; Cysteine; Cytokines; Eosinophilia; Eosinophils; Interleukin-5; Leukocyte Count; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Mice; Mice, Inbred CBA; Mice, Transgenic; Urea | 1999 |
Benzofuranyl ureas with potent cardiovascular teratogenicity in rats.
Topics: Abnormalities, Drug-Induced; Animals; Aorta, Thoracic; Benzofurans; Cardiovascular System; Cryptorchidism; Embryo Implantation; Enzyme Inhibitors; Esophagus; Female; Fetal Weight; Fetus; Hernia, Diaphragmatic; Lipoxygenase Inhibitors; Male; Maternal-Fetal Exchange; Pregnancy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Subclavian Artery; Teratogens; Thymus Gland; Urea; Uterus | 2000 |
Region-specific DNA damage by AT-specific DNA-reactive drugs is predicted by drug binding specificity.
Topics: Alu Elements; Antineoplastic Agents, Alkylating; Apolipoproteins B; AT Rich Sequence; Benzofurans; Binding Sites; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA; DNA Adducts; DNA Damage; DNA, Mitochondrial; Duocarmycins; Genome, Human; Globins; Humans; Hypoxanthine Phosphoribosyltransferase; Indoles; Nuclear Matrix; Polymerase Chain Reaction; Proto-Oncogene Proteins c-myc; Replication Origin; Tumor Cells, Cultured; Urea | 2000 |
Inhibition of enterotoxin-induced porcine colonic secretion by diarylsulfonylureas in vitro.
Topics: Amiloride; Animals; Anions; Antineoplastic Agents; Benzofurans; Biological Transport; Bumetanide; Cadmium Chloride; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Diuretics; Enterotoxins; In Vitro Techniques; Intestinal Mucosa; Phenylurea Compounds; Stilbenes; Sulfonylurea Compounds; Swine; Tetrodotoxin; Urea; Vasoactive Intestinal Peptide | 2000 |
Does the antitumor cyclopropylpyrroloindole antibiotic CC-1065 cross-link DNA in tumor cells?
Topics: Antibiotics, Antineoplastic; Benzofurans; Cell Division; Cross-Linking Reagents; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA; DNA, Neoplasm; Duocarmycins; HeLa Cells; Humans; Indoles; Leucomycins; Urea | 2001 |
Urea as a PCDD/F inhibitor in municipal waste incineration.
Topics: Benzofurans; Equipment Design; Incineration; Kinetics; Polychlorinated Dibenzodioxins; Refuse Disposal; Soil Pollutants; Urea | 2001 |
PCDD/F reduction in incinerator flue gas by adding urea to RDF feedstock.
Topics: Air Pollutants; Air Pollution; Benzofurans; Chlorophenols; Environmental Pollutants; Incineration; Polychlorinated Dibenzodioxins; Polymers; Refuse Disposal; Soil Pollutants; Urea; Waste Products | 2001 |
Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents.
Topics: Aldehyde Oxidoreductases; Animals; Animals, Newborn; Benzofurans; Diaphragm; Disease Models, Animal; Enzyme Inhibitors; Female; Hernia, Diaphragmatic; Pregnancy; Rats; Rats, Sprague-Dawley; Retinal Dehydrogenase; Urea | 2003 |
The DNA minor groove-alkylating cyclopropylpyrroloindole drugs adozelesin and bizelesin induce different DNA damage response pathways in human colon carcinoma HCT116 cells.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Benzofurans; Cell Cycle; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Duocarmycins; Humans; Indoles; Signal Transduction; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Urea | 2003 |
Different DNA lesions trigger distinct cell death responses in HCT116 colon carcinoma cells.
Topics: Aminoglycosides; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Benzofurans; Cell Cycle; Cell Death; Cell Proliferation; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Dose-Response Relationship, Drug; Duocarmycins; Enediynes; HCT116 Cells; Humans; Indoles; Inhibitory Concentration 50; Urea | 2004 |
Cleaner co-combustion of lignite-biomass-waste blends by utilising inhibiting compounds of toxic emissions.
Topics: Air Pollutants; Air Pollution; Benzofurans; Biomass; Cities; Coal; Incineration; Polychlorinated Dibenzodioxins; Urea; Waste Management | 2007 |
Pharmacogenomic analyses of targeting the AT-rich malaria parasite genome with AT-specific alkylating drugs.
Topics: Alkylating Agents; Animals; Antimalarials; Base Composition; Benzofurans; Binding Sites; Centromere; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA, Protozoan; Duocarmycins; Genomic Islands; Humans; Indoles; Inhibitory Concentration 50; Molecular Structure; Parasitic Sensitivity Tests; Pharmacogenetics; Plasmodium falciparum; Sensitivity and Specificity; Urea | 2007 |
5-ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-alpha and mTOR for the treatment of breast cancer.
Topics: Animals; Benzofurans; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Microsomes; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Tumor Burden; Urea | 2010 |
Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists.
Topics: Benzofurans; Platelet Activation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Urea | 2010 |
Synthesis and antitubercular evaluation of amidoalkyl dibenzofuranols and 1H-benzo[2,3]benzofuro[4,5-e][1,3]oxazin-3(2H)-ones.
Topics: Antitubercular Agents; Benzofurans; Catalysis; Cyclization; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazines; Phosphoric Acids; Polymers; Silicon Dioxide; Temperature; Urea | 2011 |
[Inhibition of chlorobenzene formation via various routes during waste incineration by ammonium sulfate and urea].
Topics: Ammonium Sulfate; Benzofurans; Chlorobenzenes; Coal Ash; Dioxins; Hexachlorobenzene; Incineration; Polymers; Urea | 2014 |
Effect of ammonium sulfate and urea on PCDD/F formation from active carbon and possible mechanism of inhibition.
Topics: Ammonium Sulfate; Benzofurans; Carbon; Dibenzofurans, Polychlorinated; Polychlorinated Dibenzodioxins; Urea | 2014 |
Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzofurans; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles; Torpedo; Urea | 2015 |