urea and alpha-synuclein

urea has been researched along with alpha-synuclein in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's8 (53.33)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Hong, S; Kang, T; Kim, HJ; Moon, J; Oh, S; Paik, SR; Yi, J1
Kamitani, T; Kito, K; Mori, F; Takahashi, H; Tanaka, T; Tanji, K; Wakabayashi, K1
Ahmad, MF; Ramakrishna, T; Raman, B; Rao, ChM1
Cernocká, H; Kurzątkowska, K; Ostatná, V; Paleček, E1
Deniz, AA; Ferreon, AC; Gambin, Y; Moosa, MM1
Buehl, CJ; Deng, X; Hovde, S; Kuo, MH; Liu, M; McAndrew, MJ; Xu, X1
Basak, S; Chattopadhyay, K; Prasad, GV; Varkey, J1
Bergström, AL; Boas, U; Heegaard, PM; Larsen, HM; Laumann, K1
de Oliveira, GAP; Silva, JL1
Aarsland, D; Ballard, C; Ffytche, D; Velayudhan, L1
Andreasen, M; Barker, RA; Fazal, SV; Fragniere, AMC; Scott, K; Stott, SRW1
Alijanvand, SH; Burdukiewicz, M; Christensen, LFB; Dueholm, MS; Herbst, FA; Kjeldal, H; Otzen, DE1
Abadi, AH; Abdel-Halim, M; AlNajjar, YT; Becker, W; ElHady, AK; Engel, M; Gabr, M; Salah, M; Wilms, G1
Abadi, AH; Abdel-Halim, M; Aboushady, Y; Becker, W; ElHady, AK; Engel, M; Gabr, M; Salah, M; Wilms, G1
Adlard, PA; Barnham, KJ; Billings, JL; Cherny, RA; Finkelstein, DI; Saleh, E; Shukla, JJ; Stefanova, N1

Reviews

1 review(s) available for urea and alpha-synuclein

ArticleYear
New Therapeutic Strategies for Lewy Body Dementias.
    Current neurology and neuroscience reports, 2017, Volume: 17, Issue:9

    Topics: alpha-Synuclein; Cholinesterase Inhibitors; Disease Management; Genetic Therapy; Humans; Lewy Body Disease; Parkinson Disease; Piperidines; Stem Cell Transplantation; Urea

2017

Other Studies

14 other study(ies) available for urea and alpha-synuclein

ArticleYear
Characterization of surface-confined alpha-synuclein by surface plasmon resonance measurements.
    Langmuir : the ACS journal of surfaces and colloids, 2006, Jan-03, Volume: 22, Issue:1

    Topics: alpha-Synuclein; Coated Materials, Biocompatible; Protein Denaturation; Recombinant Proteins; Surface Plasmon Resonance; Thermodynamics; Urea

2006
NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1.
    The American journal of pathology, 2006, Volume: 169, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; alpha-Synuclein; Binding Sites; Brain; Carrier Proteins; Cells, Cultured; Down-Regulation; Gene Expression Profiling; Guanidine; Humans; Lewy Bodies; NEDD8 Protein; Nerve Tissue Proteins; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Protein Transport; RNA Interference; RNA, Messenger; Sodium Dodecyl Sulfate; Solubility; Solutions; Transcription Factors; Ubiquitins; Urea; Yeasts

2006
Effect of phosphorylation on alpha B-crystallin: differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant.
    Journal of molecular biology, 2008, Jan-25, Volume: 375, Issue:4

    Topics: alpha-Crystallin B Chain; alpha-Synuclein; Amino Acid Substitution; Amyloid; Aspartic Acid; Citrate (si)-Synthase; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Heat-Shock Proteins, Small; Hot Temperature; Humans; Insulin; Molecular Chaperones; Phosphorylation; Protein Denaturation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Sodium Dodecyl Sulfate; Surface-Active Agents; Urea

2008
Native and denatured forms of proteins can be discriminated at edge plane carbon electrodes.
    Analytica chimica acta, 2012, Jul-20, Volume: 735

    Topics: alpha-Synuclein; Animals; Cattle; Chickens; Electrochemical Techniques; Electrodes; Fructose-Bisphosphate Aldolase; Graphite; Humans; Protein Denaturation; Proteins; Serum Albumin; Tryptophan; Tyrosine; Urea

2012
Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-30, Volume: 109, Issue:44

    Topics: alpha-Synuclein; Fluorescence Resonance Energy Transfer; Methylamines; Molecular Chaperones; Protein Conformation; Urea

2012
Resolving acetylated and phosphorylated proteins by neutral urea Triton-polyacrylamide gel electrophoresis: NUT-PAGE.
    BioTechniques, 2014, Volume: 57, Issue:2

    Topics: Acetylation; alpha-Synuclein; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Histones; Humans; Hydrogen-Ion Concentration; Octoxynol; Phosphorylation; Protein Processing, Post-Translational; Urea

2014
Early sodium dodecyl sulfate induced collapse of α-synuclein correlates with its amyloid formation.
    ACS chemical neuroscience, 2015, Feb-18, Volume: 6, Issue:2

    Topics: alpha-Synuclein; Amyloid; Benzothiazoles; Circular Dichroism; Entropy; Escherichia coli; Fluorescence Resonance Energy Transfer; Glycerol; Microscopy, Electron, Transmission; Mutation; Protein Structure, Secondary; Recombinant Proteins; Sodium Dodecyl Sulfate; Solutions; Solvents; Spectrometry, Fluorescence; Thiazoles; Urea

2015
Urea and thiourea modified polypropyleneimine dendrimers clear intracellular α-synuclein aggregates in a human cell line.
    Biomacromolecules, 2015, Jan-12, Volume: 16, Issue:1

    Topics: alpha-Synuclein; Cell Line; Cell Line, Tumor; Dendrimers; Humans; Intracellular Membranes; Polypropylenes; Thiourea; Urea

2015
The push-and-pull hypothesis in protein unfolding, misfolding and aggregation.
    Biophysical chemistry, 2017, Volume: 231

    Topics: alpha-Synuclein; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protein Unfolding; Proteins; Scattering, Small Angle; Urea; X-Ray Diffraction

2017
Hyperosmotic stress induces cell-dependent aggregation of α-synuclein.
    Scientific reports, 2019, 02-19, Volume: 9, Issue:1

    Topics: alpha-Synuclein; Animals; Benzothiazoles; Blotting, Western; Cell Death; Cell Line; Cell Survival; Electrophoresis, Polyacrylamide Gel; HEK293 Cells; Hot Temperature; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Mice; Osmolar Concentration; Parkinson Disease; Sodium Chloride; Sodium Dodecyl Sulfate; Urea

2019
Identification of amyloidogenic proteins in the microbiomes of a rat Parkinson's disease model and wild-type rats.
    Protein science : a publication of the Protein Society, 2021, Volume: 30, Issue:9

    Topics: alpha-Synuclein; Amino Acid Sequence; Amyloid; Amyloidogenic Proteins; Animals; Bacterial Proteins; Benzothiazoles; Biofilms; Disease Models, Animal; Endopeptidase K; Feces; Female; Formates; Gastrointestinal Microbiome; Humans; Hydrogen-Ion Concentration; Microbial Consortia; Parkinson Disease; Protein Aggregates; Rats; Rats, Transgenic; Urea

2021
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.
    European journal of medicinal chemistry, 2022, Jan-05, Volume: 227

    Topics: alpha-Synuclein; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Dyrk Kinases; HEK293 Cells; Humans; Molecular Structure; Neuroprotective Agents; Protein Aggregates; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship; Thiazoles; Urea

2022
Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases.
    ACS chemical neuroscience, 2021, 11-17, Volume: 12, Issue:22

    Topics: alpha-Synuclein; Humans; Neurodegenerative Diseases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; tau Proteins; Urea

2021
The Compound ATH434 Prevents Alpha-Synuclein Toxicity in a Murine Model of Multiple System Atrophy.
    Journal of Parkinson's disease, 2022, Volume: 12, Issue:1

    Topics: alpha-Synuclein; Animals; Disease Models, Animal; Humans; Iron; Mice; Mice, Transgenic; Multiple System Atrophy; Parkinson Disease; Urea

2022